Areca-nut-flavored product

Abstract

The invention provides a betel nut flavored product. The betel nut flavored product comprises arecoline salt. According to the present invention, the arecoline salt is applied to the product, such that the user can ingest the arecoline during the smoking, the effect similar to the areca-nut chewing effect is produced, and the irritation is low.

Description

[0001] This divisional application is a divisional application of a Chinese patent application with the application number 202010587899.7, the application date of June 24, 2020, and the invention title of "Areca-flavored products". Technical Field

[0002] This application belongs to the technical field of chemical synthesis and relates to an areca-flavored product. Background Art

[0003] Arecoline, with the chemical name "methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate", is an oily liquid and has a cholinomimetic effect. Arecoline is a compound with great application value, and its preparation methods and applications have always attracted people's attention.

[0004] However, arecoline has unstable properties, and there are currently no commercial products available. It is impossible to determine the conversion rate of arecoline, let alone whether it can enable smokers to achieve the effect of chewing areca nuts; in addition, the application of arecoline salts in products has not been found yet. Summary of the Invention

[0005] This application provides an areca-flavored product, and the product contains arecoline salts.

[0006] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a coordinating acid.

[0007] In some embodiments, the coordinating acid of the arecoline salt is selected from at least one of the following:

[0008] Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0009] In some embodiments, the molar ratio of the arecoline to the coordinating acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, and more preferably 0 < n ≤ 2.

[0010] In some embodiments, the article is an aerosol-forming substrate for being atomized to generate an aerosol for inhalation.

[0011] In some embodiments, the aerosol-forming matrix is ​​in a liquid phase, and is used to be atomized by any one of a heated atomization device, an ultrasonic atomization device, an air compression atomization device, and a press-type spray device to generate an aerosol.

[0012] In some embodiments, the aerosol-generating substrate is a solid phase configured to generate an aerosol for inhalation when heated below the ignition point.

[0013] In some embodiments, the article is a popping bead for use in an aerosol-generating article.

[0014] In some embodiments, the article is chewing gum.

[0015] In some embodiments, the product is a beverage.

[0016] The present application uses arecoline salt in the product, and the user can ingest arecoline when smoking it, and produce a similar effect to chewing betel nut, but with lower irritation. DETAILED DESCRIPTION

[0017] The present application will be further described in conjunction with the following examples.

[0018] Implementation method 1:

[0019] Embodiment 1 of the present application provides a use of an arecoline salt in preparing an aerosol-forming matrix.

[0020] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a complexing acid.

[0021] In some embodiments, the complexing acid of the arecoline salt is selected from at least one of the following:

[0022] Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine (methionine), phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0023] In some embodiments, the molar ratio of arecoline to the complex acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0024] In some embodiments, when preparing the aerosol-forming substrate, based on the total mass of the aerosol-forming substrate, the mass percentage of the arecoline salt is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, more preferably 2% - 10%, more preferably 2% - 5%, more preferably 2% - 4%.

[0025] In some embodiments, when preparing the aerosol-forming substrate, the substances added to the arecoline salt include a solvent.

[0026] In some embodiments, the solvent is selected from at least one of the following:

[0027] 1,2 - propylene glycol, 1,3 - propylene glycol, glycerol, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol dimethyl ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, sweet orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, salad oil.

[0028] In some embodiments, the solvent includes glycerol, and the mass percentage of the glycerol is 0 - 90%.

[0029] In some embodiments, the solvent includes propylene glycol, and the mass percentage of the propylene glycol is 9% - 99.8%.

[0030] In some embodiments, the substances added to the arecoline salt further include a flavoring agent.

[0031] In some embodiments, the flavoring agent is selected from at least one of the following:

[0032] Nerol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, alpha-terpineol, citronellol, beta-phenylethanol, linalool oxide, geraniol, isopentanol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, valeric acid, hexanoic acid, edible acetic acid, octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isopentyl acetate, amyl formate, geranyl formate, Butyl formate, benzyl formate, leaf formate, γ-decanolide, γ-nonanolide, γ-octanolactone, γ-heptanolide, γ-undecalactone, γ-dodecalactone, benzaldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropionaldehyde, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans, trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3 (5 or 6)-dimethylpyrazine 、2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-acetylpyrazine, acetophenone, beta-ionone, Damascena 2 (Firmenich), diacetyl, methyl ionone, acetoin (acetyl methyl alcohol), acetoin (acetyl methyl alcohol), methyl heptenone, vanillin, ethyl vanillin, dihydrocoumarin, raspberry ketone, anisole, methyl cedar ether, methyl-2-methyl-3-furanyl disulfide, wintergreen oil, clove bud oil, ten times sweet orange oil, rosewood oil, Geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, vanillin, Turu extract, Peruvian extract, oak extract, espresso supercritical extraction extract (water soluble), cocoa extract, coffee tincture, Angelica dahurica tincture, pandan extract, vanilla extract, iris oil or extract, jasmine extract, tree moss extract (amber fragrance), tamarind extract, Zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco absolute oil A, flue-cured tobacco butt fragrance extract, sun-dried tobacco butt fragrance extract.

[0033] It should be noted that the fragrances are not limited to the substances listed above, and any fragrances that comply with FEMA codes and CAS codes can be used.

[0034] In some embodiments, the subject added to the arecoline salt does not contain nicotine and / or nicotine salt.

[0035] Implementation method 2:

[0036] Embodiment 2 of the present application provides an aerosol-forming substrate, wherein the aerosol-forming substrate comprises:

[0037] Arecoline salt;

[0038] Solvents;

[0039] Optionally, flavoring agent.

[0040] Preferably, based on the total mass of the aerosol-forming matrix, the mass percentage of the arecoline salt is 0.2% to 15%, preferably 1% to 15%, more preferably 2% to 15%, more preferably 2% to 12%, more preferably 2% to 10%, more preferably 2% to 8%, more preferably 2% to 5%, more preferably 2% to 4%, more preferably 2% to 3%, and more preferably 3% to 4%.

[0041] Preferably, the complexing acid of the arecoline salt comprises at least one of the following:

[0042] Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, benzoic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine (methionine), phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0043] Preferably, the arecoline salt is arecoline hydrobromide and / or arecoline benzoate.

[0044] Preferably, the arecoline salt is obtained by neutralizing arecoline extracted from betel nut with the complex acid.

[0045] Preferably, the arecoline salt is arecoline hydrobromide or arecoline benzoate, and the preparation method is: using ethyl acetate as an extractant to extract arecoline from areca nut, adjusting the pH value of the extract to 7.5-8.5, taking the ethyl acetate layer, and then adding hydrobromic acid or benzoic acid to generate arecoline salt crystals, and the arecoline salt crystals are recrystallized to obtain arecoline hydrobromide or arecoline benzoate.

[0046] Preferably, the solvent comprises at least one of the following:

[0047] Propylene glycol, glycerin, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric glyceride, isopropyl alcohol, palm oil, peanut oil, corn oil, salad oil.

[0048] Preferably, the solvent includes glycerol, and the mass percentage of glycerol in the aerosol-forming matrix is ​​0% to 90%, preferably 0% to 80%, more preferably 0% to 70%, more preferably 0% to 60%, more preferably 10% to 60%, more preferably 20% to 60%, more preferably 30% to 60%, more preferably 40% to 60%, and more preferably 50% to 60%.

[0049] Preferably, the solvent includes propylene glycol, and the mass percentage of propylene glycol in the aerosol-forming matrix is ​​9% to 99.8%, preferably 9% to 90%, more preferably 9% to 80%, more preferably 9% to 70%, more preferably 9% to 60%, more preferably 9% to 50%, more preferably 20% to 50%, more preferably 30% to 50%, and more preferably 35% to 45%.

[0050] Preferably, the aerosol-forming substrate comprises a flavoring agent, and the flavoring agent is selected from at least one of the following:

[0051] Nerol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, alpha-terpineol, citronellol, beta-phenylethanol, linalool oxide, geraniol, isopentanol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, valeric acid, hexanoic acid, edible acetic acid, octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isopentyl acetate, amyl formate, geranyl formate, Butyl formate, benzyl formate, leaf formate, γ-decanolide, γ-nonanolide, γ-octanolactone, γ-heptanolide, γ-undecalactone, γ-dodecalactone, benzaldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropionaldehyde, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans, trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3 (5 or 6)-dimethylpyrazine 、2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-acetylpyrazine, acetophenone, beta-ionone, Damascena 2 (Firmenich), diacetyl, methyl ionone, acetoin (acetyl methyl alcohol), acetoin (acetyl methyl alcohol), methyl heptenone, vanillin, ethyl vanillin, dihydrocoumarin, raspberry ketone, anisole, methyl cedar ether, methyl-2-methyl-3-furanyl disulfide, wintergreen oil, clove bud oil, ten times sweet orange oil, rosewood oil, Geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, vanillin, Turu extract, Peruvian extract, oak extract, espresso supercritical extraction extract (water soluble), cocoa extract, coffee tincture, Angelica dahurica tincture, pandan extract, vanilla extract, iris oil or extract, jasmine extract, tree moss extract (amber fragrance), tamarind extract, Zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco absolute oil A, flue-cured tobacco butt fragrance extract, sun-dried tobacco butt fragrance extract.

[0052] It should be noted that the fragrances are not limited to the substances listed above, and any fragrances that comply with FEMA codes and CAS codes can be used.

[0053] Experimental test method:

[0054] The arecoline salt is selected from arecoline hydrobromide. The solvent is selected from a mixture of glycerol and propylene glycol in a mass ratio of 1:1.

[0055] The smoke machine was used to smoke according to international standards, and the aerosol atomized from the aerosol-forming matrix was collected with a Cambridge filter. The mass of the hydrobromide of arecoline in the aerosol was tested as m1. The mass of the hydrobromide of arecoline in the remaining aerosol-forming matrix was tested as m2, and the mass of the total hydrobromide of arecoline in the aerosol-forming matrix was m0. The conversion rate k=m1 / (m0-m2) was calculated.

[0056] Among them, the international standards involved can be referred to:

[0057] CORESTA RECOMMENDED METHOD N°81, Afnor standardization XP D90-300-3, International Standard ISO 20768:2018and PD CEN / TR 17236:2018.

[0058] The parameters for smoking electronic cigarettes are as follows:

[0059] Puff Duration 3.0s±0.1s Puff Volume 55mL±0.3mL Puff Frequency 30s±0.5s Puff of Each Group 20 Group Interval Time 300s±120s Maximum Flow 18.5mL / s±0.1mL / s Pressure Drop <50hPa Group 5 Total Number of Puffs 100 Total Duration of Vaporization 300s

[0060] Smoking experience test:

[0061] After the aerosol-forming matrix is ​​atomized, the puffing experience of the aerosol-forming matrix can be evaluated from two aspects: the first aspect is the satisfaction of the puffer after absorbing the arecoline salt after puffing; the second aspect is the discomfort of the puffer after consuming too much arecoline salt. Through the puffing evaluation of multiple people and the comprehensive experience of the two aspects, different aerosol-forming matrices are scored from 0 to 5 points to obtain an embodiment with a better puffing experience.

[0062] Experimental test results:

[0063]

[0064] It can be seen from the above experimental test results that as the content of arecoline hydrobromide in the aerosol-forming matrix increases, the conversion rate tends to decrease. When the content of arecoline hydrobromide in the aerosol-forming matrix reaches 15%, the conversion rate is still higher than 50%. In addition, after the aerosol-forming matrix with different arecoline hydrobromide contents is atomized into an aerosol, the content of arecoline salt in the aerosol is different, and the experience of the smoker is different. When the content of arecoline salt in the aerosol-forming matrix is ​​lower than 0.2%, the smoker does not feel the satisfaction brought by the intake of arecoline; as the content increases, the satisfaction increases; after exceeding 5%, the discomfort brought by the intake of arecoline salt begins to appear, and under experimental conditions, it gradually appears with the increase of content; after exceeding 15%, the discomfort is unacceptable.

[0065] Implementation method three:

[0066] Embodiment 3 of the present application provides an aerosol generating system, including an atomizing device and the aerosol forming substrate described in embodiment 2;

[0067] The atomizing device is configured to atomize the aerosol-forming substrate to form an aerosol.

[0068] In some embodiments, the atomization device is a heated atomization device.

[0069] In some embodiments, the nebulization device is an ultrasonic nebulization device.

[0070] In some embodiments, the aerosol-forming base comprises arecoline salt, glycerol and propylene glycol.

[0071] In some embodiments, the oscillation frequency of the ultrasonic atomization device is greater than 1 MHz.

[0072] In some embodiments, the atomization device is an air compression atomization device or a press-type spray device.

[0073] In some embodiments, the aerosol-forming base comprises arecoline salt, ethanol and water.

[0074] Implementation method 4:

[0075] Embodiment 4 of the present application provides a use of an arecoline salt in the manufacture of an aerosol-generating product.

[0076] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a complexing acid.

[0077] In some embodiments, the complexing acid of the arecoline salt is selected from at least one of the following:

[0078] Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine (methionine), phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0079] In some embodiments, the molar ratio of arecoline to the complex acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0080] In some embodiments, when manufacturing the aerosol-generating article, based on the total mass of the raw materials of the aerosol-generating article, the mass percentage of the arecoline salt is 0.2% to 15%, preferably 1% to 15%, more preferably 2% to 15%, more preferably 2% to 10%, more preferably 2% to 5%, more preferably 2% to 4%, and even more preferably 3% to 4%.

[0081] In some embodiments, when manufacturing the aerosol-generating article, the substances added to the arecoline salt include: aerosolizing agents, binders, and plant fibers.

[0082] In some embodiments, when manufacturing the aerosol-generating article, based on the total mass of the raw materials of the aerosol-generating article, the mass percentage of the aerosolizing agent is 5% to 30%, preferably 10% to 30%, more preferably 10% to 25%, more preferably 15% to 25%.

[0083] In some embodiments, the aerosolizing agent is selected from at least one of the following:

[0084] 1,2-propanediol, 1,3-propanediol, glycerol, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol dimethyl ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, sweet orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, salad oil.

[0085] In some embodiments, when manufacturing the aerosol-generating article, based on the total mass of the raw materials of the aerosol-generating article, the mass percentage of the binder is 1% to 20%, preferably 1% to 15%, more preferably 1% to 10%, more preferably 3% to 10%, more preferably 5% to 10%.

[0086] In some embodiments, the binder is selected from at least one of the following:

[0087] Carboxymethyl cellulose, hydroxypropyl methyl cellulose, polyvinyl alcohol, rosin, xanthan gum, gum arabic, guar gum, chitosan, pectin, locust bean gum, starch, sodium alginate, shellac.

[0088] In some embodiments, when manufacturing the aerosol generating product, the mass percentage of the plant fiber is 40% to 80%, preferably 40% to 70%, more preferably 50% to 70%, more preferably 50% to 65%, and more preferably 50% to 60%, based on the total mass of the raw materials of the aerosol generating product.

[0089] In some embodiments, the plant fiber is selected from at least one of the following:

[0090] Betel nut fiber, wood pulp fiber, hemp pulp fiber, cotton pulp fiber, bagasse pulp fiber, bamboo pulp fiber, coconut pulp fiber.

[0091] In some embodiments, the subject added to the arecoline salt further includes a flavoring agent.

[0092] In some embodiments, the flavoring agent is selected from at least one of the following:

[0093] Nerol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, alpha-terpineol, citronellol, beta-phenylethanol, linalool oxide, geraniol, isopentanol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, valeric acid, hexanoic acid, edible acetic acid, octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isopentyl acetate, amyl formate, geranyl formate, Butyl formate, benzyl formate, leaf formate, γ-decanolide, γ-nonanolide, γ-octanolactone, γ-heptanolide, γ-undecalactone, γ-dodecalactone, benzaldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropionaldehyde, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans, trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3 (5 or 6)-dimethylpyrazine 、2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-acetylpyrazine, acetophenone, beta-ionone, Damascena 2 (Firmenich), diacetyl, methyl ionone, acetoin (acetyl methyl alcohol), acetoin (acetyl methyl alcohol), methyl heptenone, vanillin, ethyl vanillin, dihydrocoumarin, raspberry ketone, anisole, methyl cedar ether, methyl-2-methyl-3-furanyl disulfide, wintergreen oil, clove bud oil, ten times sweet orange oil, rosewood oil, Geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, vanillin, Turu extract, Peruvian extract, oak extract, espresso supercritical extraction extract (water soluble), cocoa extract, coffee tincture, Angelica dahurica tincture, pandan extract, vanilla extract, iris oil or extract, jasmine extract, tree moss extract (amber fragrance), tamarind extract, Zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco absolute oil A, flue-cured tobacco butt fragrance extract, sun-dried tobacco butt fragrance extract.

[0094] It should be noted that the fragrances are not limited to the substances listed above, and any fragrances that comply with FEMA codes and CAS codes can be used.

[0095] In some embodiments, the subject added to the arecoline salt does not contain tobacco components.

[0096] In some embodiments, the method of manufacturing the aerosol-generating article comprises one of a papermaking process, a dry papermaking process, a thick pulp process, and a roller pressing process.

[0097] Implementation method five:

[0098] Embodiment 5 of the present application provides an aerosol generating article, the raw materials of which include arecoline salt, aerosolizing agent, binder and plant fiber.

[0099] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a coordinating acid.

[0100] In some embodiments, the coordinating acid of the arecoline salt is selected from at least one of the following:

[0101] formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0102] In some embodiments, the molar ratio of the arecoline to the coordinating acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0103] In some embodiments, based on the total mass of the raw materials, the mass percentage of the arecoline salt is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, more preferably 2% - 10%, more preferably 2% - 5%, more preferably 2% - 4%, and even more preferably 3% - 4%.

[0104] In some embodiments, based on the total mass of the raw materials, the mass percentage of the aerosolizing agent is 5% - 30%, preferably 10% - 30%, more preferably 10% - 25%, more preferably 15% - 25%.

[0105] In some embodiments, the aerosolizing agent is selected from at least one of the following:

[0106] 1,2-propanediol, 1,3-propanediol, glycerol, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol dimethyl ether, ethanol, water, triethyl citrate, triacetin, caprylic capric triglyceride, isopropanol, sweet orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, salad oil.

[0107] In some embodiments, based on the total mass of the raw materials, the mass percentage of the binder is 1% to 20%, preferably 1% to 15%, more preferably 1% to 10%, more preferably 3% to 10%, more preferably 5% to 10%.

[0108] In some embodiments, the binder is selected from at least one of the following:

[0109] Carboxymethyl cellulose, hydroxypropyl methyl cellulose, polyvinyl alcohol, rosin, xanthan gum, gum arabic, guar gum, chitosan, pectin, locust bean gum, starch, sodium alginate, shellac.

[0110] In some embodiments, based on the total mass of the raw material, the mass percentage of the plant fiber is 40% to 80%, preferably 40% to 70%, more preferably 50% to 70%, more preferably 50% to 65%, and more preferably 50% to 60%.

[0111] In some embodiments, the plant fiber is selected from at least one of the following:

[0112] Betel nut fiber, wood pulp fiber, hemp pulp fiber, cotton pulp fiber, bagasse pulp fiber, bamboo pulp fiber, coconut pulp fiber.

[0113] In some embodiments, the raw material further includes a flavoring agent.

[0114] In some embodiments, the flavoring agent is selected from at least one of the following:

[0115] Nerol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, alpha-terpineol, citronellol, beta-phenylethanol, linalool oxide, geraniol, isopentanol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, valeric acid, hexanoic acid, edible acetic acid, octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isopentyl acetate, amyl formate, geranyl formate, Butyl formate, benzyl formate, leaf formate, γ-decanolide, γ-nonanolide, γ-octanolactone, γ-heptanolide, γ-undecalactone, γ-dodecalactone, benzaldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropionaldehyde, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans, trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3 (5 or 6)-dimethylpyrazine 、2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-acetylpyrazine, acetophenone, beta-ionone, Damascena 2 (Firmenich), diacetyl, methyl ionone, acetoin (acetyl methyl alcohol), acetoin (acetyl methyl alcohol), methyl heptenone, vanillin, ethyl vanillin, dihydrocoumarin, raspberry ketone, anisole, methyl cedar ether, methyl-2-methyl-3-furanyl disulfide, wintergreen oil, clove bud oil, ten times sweet orange oil, rosewood oil, Geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, vanillin, Turu extract, Peruvian extract, oak extract, espresso supercritical extraction extract (water soluble), cocoa extract, coffee tincture, Angelica dahurica tincture, pandan extract, vanilla extract, iris oil or extract, jasmine extract, tree moss extract (amber fragrance), tamarind extract, Zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco absolute oil A, flue-cured tobacco butt fragrance extract, sun-dried tobacco butt fragrance extract.

[0116] It should be noted that the fragrances are not limited to the substances listed above, and any fragrances that comply with FEMA codes and CAS codes can be used.

[0117] In some embodiments, the feedstock contains no tobacco components.

[0118] Embodiment 1:

[0119] Prepare heat-not-burn cigarettes as follows:

[0120] Step 1: Prepare the sheet substrate. Select the solid residue of betel nut extract, soak it in water at a temperature of 60 to 80°C for 0.5 to 2 hours, filter it, and then beat the filtered solid to obtain a slurry, weigh 50 to 70 parts of the slurry and 3 to 10 parts of a solid binder by weight, mix them evenly, send the mixed slurry to a papermaking machine for papermaking and forming, and dry it to a moisture content of about 10 to 15% to obtain a sheet substrate;

[0121] The solid binder may be one or more of carboxymethyl cellulose, hydroxypropyl methyl cellulose, polyvinyl alcohol, rosin, xanthan gum, gum arabic, guar gum, chitosan, pectin, locust bean gum, starch, sodium alginate, and shellac.

[0122] Step 2: Prepare a coating liquid. Weigh 1 to 50 parts of arecoline salt, 2 to 20 parts of spices, and 40 to 80 parts of atomizers by weight, mix them evenly, and obtain a coating liquid;

[0123] Among them, the atomizer is a mixture of glycerin and propylene glycol, and the mixing ratio is 3 to 5:1.

[0124] Step 3: coating the thin slice base. Weigh the coating liquid obtained in step 2 according to 25% to 40% of the weight of the thin slice base obtained in step 1, spray the coating liquid onto the thin slice base, and let it stand for 40 to 60 hours under constant temperature and humidity conditions to obtain a plant thin slice containing arecoline salt;

[0125] Step 4: preparing a heat-not-burn cigarette. The plant slices obtained in step 3 are made into cigarette sticks according to the size, and the cigarette sticks are connected to the filter tip to obtain a heat-not-burn cigarette containing arecoline salt.

[0126] The heat-not-burn cigarette prepared by the above preparation method was heated by an aerosol generating device (the heating method adopts resistance heating), and the temperature of the surface of the heating element in the working state was tested by an infrared thermal imager. The test results are shown in the following table

[0127]

[0128] From the test results, it can be seen that the arecoline salt in the cigarette can be atomized and generate an inhalable aerosol between 150℃ and 250℃.

[0129] Smoking and sensory quality evaluation were performed compared with ordinary heat-not-burn cigarettes: the heat-not-burn cigarettes prepared by the above preparation method can absorb arecoline and produce a similar effect to chewing betel nut, with lower irritation.

[0130] Implementation method six:

[0131] Embodiment 6 of the present application provides a use of arecoline salt in preparing a liquid composition for a bursting bead; wherein, the bursting bead includes a fragile shell and the liquid composition, and the liquid composition is disposed within the fragile shell.

[0132] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a coordinating acid.

[0133] In some embodiments, the coordinating acid of the arecoline salt is selected from at least one of the following:

[0134] Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0135] In some embodiments, the molar ratio of the arecoline to the coordinating acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0136] In some embodiments, based on the total mass of the liquid composition, the mass percentage of the arecoline salt is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, more preferably 2% - 10%, more preferably 2% - 5%, more preferably 2% - 4%, and most preferably 3% - 4%.

[0137] In some embodiments, when preparing the liquid composition, the substances added to the arecoline salt include an aerosolizing agent.

[0138] In some embodiments, based on the total mass of the liquid composition, the mass percentage of the aerosolizing agent is 5% - 30%, preferably 10% - 30%, more preferably 10% - 25%, more preferably 15% - 25%.

[0139] In some embodiments, the aerosolizing agent is selected from at least one of the following:

[0140] 1,2-Propanediol, 1,3-Propanediol, Glycerin, Macrogol 200, Macrogol 400, Dipropylene Glycol Ether, Ethanol, Water, Triethyl Citrate, Triacetin, Caprylic / Decaned Glyceryl, Isopropyl Alcohol, Orange Oil, Lemon Oil, Peppermint Oil, Palm Oil, Peanut Oil, Corn Oil, Salad Oil.

[0141] In some embodiments, the subject added to the arecoline salt further includes a flavoring agent.

[0142] In some embodiments, the flavoring agent is selected from at least one of the following:

[0143] Nerol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, alpha-terpineol, citronellol, beta-phenylethanol, linalool oxide, geraniol, isopentanol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, valeric acid, hexanoic acid, edible acetic acid, octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isopentyl acetate, amyl formate, geranyl formate, Butyl formate, benzyl formate, leaf formate, γ-decanolide, γ-nonanolide, γ-octanolactone, γ-heptanolide, γ-undecalactone, γ-dodecalactone, benzaldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropionaldehyde, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans, trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3 (5 or 6)-dimethylpyrazine 、2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-acetylpyrazine, acetophenone, beta-ionone, Damascena 2 (Firmenich), diacetyl, methyl ionone, acetoin (acetyl methyl alcohol), acetoin (acetyl methyl alcohol), methyl heptenone, vanillin, ethyl vanillin, dihydrocoumarin, raspberry ketone, anisole, methyl cedar ether, methyl-2-methyl-3-furanyl disulfide, wintergreen oil, clove bud oil, ten times sweet orange oil, rosewood oil, Geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, vanillin, Turu extract, Peruvian extract, oak extract, espresso supercritical extraction extract (water soluble), cocoa extract, coffee tincture, Angelica dahurica tincture, pandan extract, vanilla extract, iris oil or extract, jasmine extract, tree moss extract (amber fragrance), tamarind extract, Zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco absolute oil A, flue-cured tobacco butt fragrance extract, sun-dried tobacco butt fragrance extract.

[0144] It should be noted that the fragrances are not limited to the substances listed above, and any fragrances that comply with FEMA codes and CAS codes can be used.

[0145] In some embodiments, the object added to the arecoline salt does not contain nicotine and / or nicotine salts.

[0146] In some embodiments, the bursting beads are implanted in the aerosol-generating article.

[0147] In some embodiments, the raw materials of the aerosol-generating article do not contain tobacco components.

[0148] Implementation method seven:

[0149] Embodiment VII of the present application provides a bursting bead, comprising a frangible shell and a liquid composition, the liquid composition being disposed within the frangible shell;

[0150] Wherein, the liquid composition comprises an arecoline salt and an aerosolizing agent.

[0151] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a coordinating acid.

[0152] In some embodiments, the coordinating acid of the arecoline salt is selected from at least one of the following:

[0153] Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0154] In some embodiments, the molar ratio of the arecoline to the coordinating acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0155] In some embodiments, based on the total mass of the liquid composition, the mass percentage of the arecoline salt is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, more preferably 2% - 10%, more preferably 2% - 5%, more preferably 2% - 4%, and most preferably 3% - 4%.

[0156] In some embodiments, the mass percentage of the atomizer is 5% to 30%, preferably 10% to 30%, more preferably 10% to 25%, and more preferably 15% to 25%, based on the total mass of the liquid composition.

[0157] In some embodiments, the aerosolizing agent is selected from at least one of the following:

[0158] 1,2-Propanediol, 1,3-Propanediol, Glycerin, Macrogol 200, Macrogol 400, Dipropylene Glycol Ether, Ethanol, Water, Triethyl Citrate, Triacetin, Caprylic / Decaned Glyceryl, Isopropyl Alcohol, Orange Oil, Lemon Oil, Peppermint Oil, Palm Oil, Peanut Oil, Corn Oil, Salad Oil.

[0159] In some embodiments, the liquid composition further comprises a flavoring agent.

[0160] In some embodiments, the flavoring agent is selected from at least one of the following:

[0161] Nerol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, alpha-terpineol, citronellol, beta-phenylethanol, linalool oxide, geraniol, isopentanol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, valeric acid, hexanoic acid, edible acetic acid, octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isopentyl acetate, amyl formate, geranyl formate, Butyl formate, benzyl formate, leaf formate, γ-decanolide, γ-nonanolide, γ-octanolactone, γ-heptanolide, γ-undecalactone, γ-dodecalactone, benzaldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropionaldehyde, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans, trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3 (5 or 6)-dimethylpyrazine 、2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-acetylpyrazine, acetophenone, beta-ionone, Damascena 2 (Firmenich), diacetyl, methyl ionone, acetoin (acetyl methyl alcohol), acetoin (acetyl methyl alcohol), methyl heptenone, vanillin, ethyl vanillin, dihydrocoumarin, raspberry ketone, anisole, methyl cedar ether, methyl-2-methyl-3-furanyl disulfide, wintergreen oil, clove bud oil, ten times sweet orange oil, rosewood oil, Geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, vanillin, Turu extract, Peruvian extract, oak extract, espresso supercritical extraction extract (water soluble), cocoa extract, coffee tincture, Angelica dahurica tincture, pandan extract, vanilla extract, iris oil or extract, jasmine extract, tree moss extract (amber fragrance), tamarind extract, Zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco absolute oil A, flue-cured tobacco butt fragrance extract, sun-dried tobacco butt fragrance extract.

[0162] It should be noted that the fragrances are not limited to the substances listed above, and any fragrances that comply with FEMA codes and CAS codes can be used.

[0163] In some embodiments, the liquid composition does not contain nicotine and / or nicotine salts.

[0164] Implementation method eight:

[0165] Embodiment 8 of the present application provides an aerosol generating product, including the bursting beads described in embodiment 7.

[0166] In some embodiments, the feedstock of the aerosol-generating article does not contain tobacco components.

[0167] In this embodiment, the aerosol generating product can be prepared by papermaking, dry papermaking, thick slurry method, and roller pressing method. Specifically, the raw materials and preparation steps of the aerosol generating product can refer to the contents described in the above embodiments.

[0168] The bursting beads can be implanted into the filter segment (not limited to this position) of the heat-not-burn cigarette by means of filter rod embedding technology (not limited to this technology). When in use, the smoker can squeeze the bursting beads to ingest substances such as arecoline.

[0169] It should be noted that, in this embodiment, there are no special restrictions on the composition of the fragile shell and its preparation process, as well as the preparation process of the explosive beads, and the techniques familiar to those skilled in the art can be used.

[0170] Embodiment 1:

[0171] The liquid composition in the popping beads was prepared according to the following formula:

[0172] Arecoline salt 10wt%, caprylic decanoic acid glyceride 80wt%, menthol 10wt%.

[0173] Preparation method: weigh the weight of arecoline salt as in the above formula, add caprylic decanoic acid glyceride and menthol under stirring, and mix well to prepare the product.

[0174] The bursting beads containing Example 1 were implanted into heat-not-burn cigarettes, and smoked and the sensory quality was evaluated compared with heat-not-burn cigarettes without bursting beads: the heat-not-burn cigarettes containing the bursting beads of Example 1 were able to take in arecoline and produce a similar effect to chewing betel nut, with lower irritation.

[0175] Implementation method nine:

[0176] Embodiment 9 of the present application provides a use of an arecoline salt in the manufacture of chewing gum.

[0177] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a complexing acid.

[0178] In some embodiments, the complexing acid of the arecoline salt is selected from at least one of the following:

[0179] Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0180] In some embodiments, the molar ratio of arecoline to the complex acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0181] In some embodiments, when manufacturing the chewing gum, based on the total mass of the raw materials of the chewing gum, the mass percentage of the arecoline salt is 0.02% - 2%, preferably 0.02% - 1.6%, more preferably 0.02% - 1.2%, more preferably 0.02% - 1%, more preferably 0.1% - 1%, more preferably 0.2% - 1%, more preferably 0.4% - 1%.

[0182] In some embodiments, when manufacturing the chewing gum, the objects added to the arecoline salt include gum base.

[0183] In some embodiments, when manufacturing the chewing gum, based on the total mass of the raw materials of the chewing gum, the mass percentage of the gum base is 20% - 75%, preferably 20% - 70%, more preferably 20% - 60%, more preferably 20% - 50%, more preferably 25% - 50%, more preferably 30% - 50%, more preferably 35% - 50%, more preferably 35% - 45%.

[0184] In some embodiments, the objects added to the arecoline salt further include sweeteners.

[0185] In some embodiments, the sweetener is selected from at least one of the following:

[0186] White granulated sugar, rock sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame potassium, sucralose, stevioside, neotame.

[0187] In some embodiments, when manufacturing the chewing gum, the mass percentage of the sweetener is 20% to 75%, preferably 20% to 70%, more preferably 20% to 60%, more preferably 20% to 50%, more preferably 25% to 50%, more preferably 25% to 40%, more preferably 25% to 35%, more preferably 30% to 35%, based on the total mass of the raw materials of the chewing gum.

[0188] In some embodiments, the objects added to the arecoline salt also include filler materials.

[0189] In some embodiments, the filler material is selected from at least one of the following:

[0190] Sodium carbonate, sodium bicarbonate, potassium carbonate, calcium carbonate, dicalcium phosphate, sodium dihydrogen phosphate.

[0191] In some embodiments, when manufacturing the chewing gum, the mass percentage of the filler material is 0.03% to 23%, preferably 0.03% to 20%, more preferably 0.03% to 15%, more preferably 0.03% to 10%, more preferably 0.5% to 10%, more preferably 1% to 10%, more preferably 1.5% to 10%, more preferably 2% to 8%, more preferably 2% to 6%, based on the total mass of the raw materials of the chewing gum.

[0192] In some embodiments, the subject added to the arecoline salt further includes a flavoring agent.

[0193] In some embodiments, the flavoring agent is selected from at least one of the following:

[0194] Mint, spearmint, cinnamon, borneol, essence.

[0195] Implementation method ten:

[0196] Embodiment 10 of the present application provides a chewing gum, the raw materials of which include arecoline salt and gum base.

[0197] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a complexing acid.

[0198] In some embodiments, the complexing acid of the arecoline salt is selected from at least one of the following:

[0199] Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0200] In some embodiments, the molar ratio of the arecoline to the complex acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0201] In some embodiments, based on the total mass of the raw materials, the mass percentage of the arecoline salt is 0.02% - 2%, preferably 0.02% - 1.6%, more preferably 0.02% - 1.2%, more preferably 0.02% - 1%, more preferably 0.1% - 1%, more preferably 0.2% - 1%, more preferably 0.4% - 1%.

[0202] In some embodiments, based on the total mass of the raw materials, the mass percentage of the gum base is 20% - 75%, preferably 20% - 70%, more preferably 20% - 60%, more preferably 20% - 50%, more preferably 25% - 50%, more preferably 30% - 50%, more preferably 35% - 50%, more preferably 35% - 45%.

[0203] In some embodiments, the raw materials further include a sweetening agent.

[0204] In some embodiments, the sweetening agent is selected from at least one of the following:

[0205] White granulated sugar, rock sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame potassium, sucralose, stevioside, neotame.

[0206] In some embodiments, based on the total mass of the raw materials, the mass percentage of the sweetener is 20% to 75%, preferably 20% to 70%, more preferably 20% to 60%, more preferably 20% to 50%, more preferably 25% to 50%, more preferably 25% to 40%, more preferably 25% to 35%, more preferably 30% to 35%.

[0207] In some embodiments, the feedstock further includes filler material.

[0208] In some embodiments, the filler material is selected from at least one of the following:

[0209] Sodium carbonate, sodium bicarbonate, potassium carbonate, calcium carbonate, dicalcium phosphate, sodium dihydrogen phosphate.

[0210] In some embodiments, based on the total mass of the raw materials, the mass percentage of the filler material is 0.03% to 23%, preferably 0.03% to 20%, further preferably 0.03% to 15%, further preferably 0.03% to 10%, further preferably 0.5% to 10%, further preferably 1% to 10%, further preferably 1.5% to 10%, further preferably 2% to 8%, further preferably 2% to 6%.

[0211] In some embodiments, the raw material further includes a flavoring agent.

[0212] In some embodiments, the flavoring agent is selected from at least one of the following:

[0213] Mint, spearmint, cinnamon, borneol, essence.

[0214] Embodiment 1:

[0215] Prepare chewing gum according to the following recipe:

[0216] Gum base 54wt%, powdered sugar 23wt%, glucose syrup 14wt%, potassium carbonate 4wt%, mint flavoring 3wt%, menthol 1wt%, arecoline salt 1wt%.

[0217] Preparation method: Heat the gum base to 70-105°C, put it into a blender and stir, add powdered sugar, and let the temperature drop to 60-80°C, then add buffer, additives, glucose syrup, and arecoline salt, and finally roll it into sheets and shape it into a finished product.

[0218] Embodiment 2:

[0219] Xylitol chewing gum was prepared according to the following formula:

[0220] Gum base 54 wt%, xylitol 23 wt%, non-sucrose 14 wt%, potassium carbonate 4 wt%, mint flavoring 3 wt%, menthol 1 wt%, arecoline salt 1 wt%.

[0221] Preparation method: Heat the gum base to 70 - 105 °C, put it into a blender and stir, add xylitol and non-sucrose, and let the temperature drop to 60 - 80 °C, then add buffer pairs, additives, arecoline salt, and finally roll into tablets to form the finished product.

[0222] For the chewing gum prepared by the above preparation method, conduct eating and sensory quality evaluations with ordinary chewing gum: The chewing gum prepared by the above preparation method can produce a similar effect to chewing areca, has low irritation, and a good taste. Since this chewing gum does not contain lime powder and cellulose, it avoids the problems of oral mucosal abrasion, irritation, and induction of oral diseases when chewing areca.

[0223] Implementation method eleven:

[0224] Embodiment XI of the present application provides a use of arecoline salt in the preparation of beverages.

[0225] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a complex acid.

[0226] In some embodiments, the complex acid of the arecoline salt is selected from at least one of the following:

[0227] Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0228] In some embodiments, the molar ratio of the arecoline to the complex acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0229] In some embodiments, when preparing the beverage, the mass percentage of the arecoline salt is 0.01% to 0.5%, preferably 0.01% to 0.4%, more preferably 0.01% to 0.3%, more preferably 0.01% to 0.2%, and more preferably 0.05% to 0.2%, based on the total mass of the beverage.

[0230] In some embodiments, when preparing the beverage, the object added to the arecoline salt includes water.

[0231] In some embodiments, when preparing the beverage, the mass percentage of the water is 75% to 90% based on the total mass of the beverage.

[0232] In some embodiments, when preparing the beverage, the object added to the arecoline salt also includes a functional ingredient.

[0233] In some embodiments, the functional ingredient is selected from at least one of the following:

[0234] Monk fruit concentrated juice, natural menthol, licorice concentrated juice, honeysuckle concentrated juice, chrysanthemum extract, kudzu root extract, loquat puree.

[0235] In some embodiments, the mass percentage of the functional ingredient is 0.5% to 2% based on the total mass of the beverage.

[0236] In some embodiments, when preparing the beverage, the object added to the arecoline salt also includes an acidity regulator.

[0237] In some embodiments, the acidity regulator is selected from at least one of the following:

[0238] Tartaric acid, malic acid, citric acid, sodium citrate.

[0239] In some embodiments, when preparing the beverage, the mass percentage of the acidity regulator is 0.1% to 5% based on the total mass of the beverage.

[0240] In some embodiments, when preparing the beverage, the subject added to the arecoline salt also includes a sweetener.

[0241] In some embodiments, the sweetener is selected from at least one of the following:

[0242] White sugar, rock sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame potassium, sucralose, stevioside, neotame.

[0243] In some embodiments, when preparing the beverage, the mass percentage of the sweetener is 0.5% to 5% based on the total mass of the beverage.

[0244] In some embodiments, when preparing the beverage, the subject added to the arecoline salt also includes an antioxidant.

[0245] In some embodiments, the antioxidant is selected from at least one of the following:

[0246] Ascorbic acid, sodium erythorbate, vitamin C, vitamin E.

[0247] In some embodiments, when preparing the beverage, the weight percentage of the antioxidant is 0.05% to 0.15% based on the total weight of the beverage.

[0248] In some embodiments, when preparing the beverage, the subject added to the arecoline salt also includes a preservative.

[0249] In some embodiments, the preservative is selected from at least one of the following:

[0250] Sodium benzoate, sodium sorbate, potassium sorbate.

[0251] In some embodiments, when preparing the beverage, the mass percentage of the preservative is 0.01% to 0.05% based on the total mass of the beverage.

[0252] In some embodiments, when preparing the beverage, the object added to the arecoline salt also includes edible flavoring.

[0253] In some embodiments, when preparing the beverage, the mass percentage of the edible flavor is 0.5% to 5% based on the total mass of the beverage.

[0254] Implementation method 12:

[0255] Embodiment 12 of the present application provides a beverage, the raw materials of which include arecoline salt and water.

[0256] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a complexing acid.

[0257] In some embodiments, the complexing acid of the arecoline salt is selected from at least one of the following:

[0258] Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0259] In some embodiments, the molar ratio of arecoline to the complex acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, and more preferably 0 < n ≤ 2.

[0260] In some embodiments, based on the total mass of the beverage, the mass percentage of the arecoline salt is 0.01% - 0.5%, preferably 0.01% - 0.4%, more preferably 0.01% - 0.3%, more preferably 0.01% - 0.2%, and more preferably 0.05% - 0.2%.

[0261] In some embodiments, based on the total mass of the beverage, the mass percentage of water is 75% - 90%.

[0262] In some embodiments, the raw materials further include functional ingredients.

[0263] In some embodiments, the functional ingredients are selected from at least one of the following:

[0264] Momordica grosvenori concentrated juice, natural menthol, Glycyrrhiza uralensis concentrated juice, Lonicera japonica concentrated juice, Chrysanthemi flos extract, Puerariae radix extract, Eriobotryae japonicae raw pulp.

[0265] In some embodiments, the mass percentage of the functional ingredients is 0.5% - 2%.

[0266] In some embodiments, the raw materials further include acid regulators.

[0267] In some embodiments, the acid regulators are selected from at least one of the following:

[0268] Tartaric acid, malic acid, citric acid, sodium citrate.

[0269] In some embodiments, the mass percentage of the acid regulators is 0.1% - 5%.

[0270] In some embodiments, the raw material further includes a sweetener.

[0271] In some embodiments, the sweetener is selected from at least one of the following:

[0272] White sugar, rock sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame potassium, sucralose, stevioside, neotame.

[0273] In some embodiments, the mass percentage of the sweetener is 0.5% to 5%.

[0274] In some embodiments, the feedstock further includes an antioxidant.

[0275] In some embodiments, the antioxidant is selected from at least one of the following:

[0276] Ascorbic acid, sodium erythorbate, vitamin C, vitamin E.

[0277] In some embodiments, the weight percentage of the antioxidant is 0.05% to 0.15%.

[0278] In some embodiments, the raw material further comprises a preservative.

[0279] In some embodiments, the preservative is selected from at least one of the following:

[0280] Sodium benzoate, sodium sorbate, potassium sorbate.

[0281] In some embodiments, the mass percentage of the preservative is 0.01% to 0.05%.

[0282] In some embodiments, the raw material further includes food flavoring.

[0283] In some embodiments, the mass percentage of the edible flavor is 0.5% to 5%.

[0284] Embodiment 1:

[0285] Prepare the drink according to the following recipe:

[0286] Arecoline salt 0.1wt%, water 88wt%, honeysuckle concentrated juice 1wt%, liquorice concentrated juice 1wt%, citric acid 2wt%, sodium citrate 2wt%, stevioside 3wt%, vitamin C 0.05wt%, sodium sorbate 0.05wt%, edible flavor 2.8wt%.

[0287] Preparation method: fully mix arecoline salt with water, honeysuckle concentrated juice, licorice concentrated juice, citric acid, sodium citrate, stevioside, vitamin C, sodium sorbate and edible flavor to prepare a beverage.

[0288] The beverage prepared by the above preparation method retains various nutrients in honeysuckle and licorice that are beneficial to the human body. The beverage is rich in ingredients such as arecoline and areca nut polyphenols. The beverage has a good taste and has various functions such as tonifying the spleen and replenishing qi, clearing away heat and detoxifying, removing phlegm and relieving cough, and relieving acute pain.

[0289] This written description uses examples to disclose the present invention, including the best mode, and also enables those skilled in the art to make and use the application. The patentable scope of the present application is defined by the claims, and may include other examples that occur to those skilled in the art. Such other examples are intended to be within the scope of the claims if they have structural elements that are not different from the literal language of the claims, or if they include equivalent structural elements that are not substantially different from the literal language of the claims. All references referenced herein are incorporated herein by reference to the extent that they will not cause inconsistency.

Claims

1. A betel nut flavored product, characterized in that: The product is a liquid-phase aerosol-forming matrix used for being atomized to generate an aerosol for inhalation; the product contains arecoline salt, which includes arecoline hydrobromide salt or arecoline benzoate salt; wherein the content of the arecoline salt in the product is between 2% and 10%.

2. The product according to claim 1, characterized in that The arecoline hydrobromide salt is obtained by neutralizing arecoline with hydrobromic acid, and the arecoline benzoate salt is obtained by neutralizing arecoline with benzoic acid.

3. The product according to claim 1, characterized in that The complexing acid of the arecoline salt also includes at least one of the following: Formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, glycine, alanine, valine, leucine, isoleucine, methionine (methionine), phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

4. The product according to any one of claims 1 to 3, characterized in that The molar ratio of the arecoline to the complex acid is n; wherein the value range of n is 0 <n≤10。 5. The product according to claim 4, characterized in that The value range of n is 0 <n≤8。 6. The product according to claim 5, characterized in that The value range of n is 0 <n≤6。 7. The product according to claim 6, characterized in that The value range of n is 0 <n≤5。 8. The product according to claim 7, characterized in that The value range of n is 0 <n≤3。 9. The product according to claim 8, characterized in that The value range of n is 0 <n≤2。 10. The article according to claim 1, characterized in that The liquid phase aerosol-forming matrix is ​​used to be atomized by any one of a heating atomization device, an ultrasonic atomization device, an air compression atomization device, and a press-type spray device to generate an aerosol.

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