Omnibearing repairing composition with high content of shea butter for skin care as well as preparation method and application of comprehensive repairing composition

The brick wall structure of the stratum corneum is repaired through a high-level shea butter comprehensive repair composition, which solves the problem that existing skin care products are difficult to effectively repair the skin barrier, and achieves the effect of enhancing the skin barrier function, reducing external stimulation, and promoting skin healing.

CN119970567AActive Publication Date: 2025-05-13MENTHOLATUM (CHINA) PHARM CO LTD
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Patent Information

Application Number
CN202510319706.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-18
Publication Date
2025-05-13
Estimated Expiration
2045-03-18

AI Technical Summary

Technical Problem

Existing skin care products are difficult to fundamentally solve the problems of sensitive skin and cannot effectively repair the skin barrier, resulting in the skin being susceptible to external irritation and causing problems such as redness, fever, and itching.

Method used

The comprehensive repair composition of high-content shea butter is adopted, including avocado resin, avocado fruit oil, ceramide, phytosterol oleate, lactic acid fermentation products, amino acids and red mycolytic alcohol, is used to form a bionic sebum film through compounding, repair the brick wall structure of the stratum corneum and enhance the skin barrier function.

Benefits of technology

Effectively repair sensitive and inflammatory skin, enhance skin barrier function, reduce external substances to the skin, maintain skin moisture, prevent moisture from evaporating, resist external irritation and damage, and promote skin healing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of cosmetics, and particularly discloses a high-content shea butter comprehensive repairing composition for skin care and a preparation method and application thereof. The high-content shea butter comprehensive repairing composition for skin care provided by the invention can repair and strengthen four barrier functions of skin, resist invasion of external physical, chemical, biological and other harmful factors, and protect the body from being damaged. The composition can also increase the moisture content of the skin, reduce the irritation of external substances to the skin and enable the skin to be in the best health state at any time.
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Description

Technical Field

[0001] The present application relates to the technical field of cosmetics, and in particular to a high-content shea butter all-round repairing composition for skin care, and a preparation method and application thereof. Background Art

[0002] Human skin refers to the tissue covering the surface of the human body and directly contacting the external environment. It has the functions of protection, sensation, secretion, excretion, and respiration. The skin is composed of the epidermis and dermis tightly combined. Among them, the epidermis is composed of stratum corneum, clear layer, granular layer and germinal layer from shallow to deep. The stratum corneum is composed of multiple layers of keratinized epithelial cells (nuclei and organelles disappear, and the cell membrane is thicker). It is lifeless and impermeable. It has the functions of preventing the outflow of tissue fluid, anti-friction and anti-infection. The cells of the germinal layer continue to proliferate and gradually migrate outward to replenish the stratum corneum that is constantly falling off. The germinal layer contains a kind of melanocyte that can produce melanin. The color of the skin is related to the amount of melanin. The dermis is composed of dense connective tissue, which is composed of the papillary layer and the reticular layer from shallow to deep, with no obvious boundary between the two layers. The thickness of the dermis is about 0.07-0.12 mm; the dermis of the palms and soles is thicker, about 1.4 mm; the eyelids and eardrums are thinner, about 0.05 mm. The papillary layer is connected to the germinal layer of the epidermis, which contains abundant capillaries, lymphatic vessels, nerve endings, tactile corpuscles and other receptors. The reticular layer is connected to the subcutaneous tissue, which contains abundant collagen fibers, elastic fibers and reticular fibers, which are interwoven into a network, making the skin more elastic and tough. The reticular layer also contains abundant blood vessels, lymphatic vessels and nerve endings.

[0003] The skin is also the human body's nervous, endocrine and immune organs, and a healthy "skin barrier" protects the skin while maintaining the homeostasis of the nervous, endocrine and immune systems. It is indispensable for achieving human health and is the basis for healthy skin, beautiful skin and a healthy body. The skin barrier is an important structure to protect the human body. It can resist the invasion of microbial antigens on the skin and resist damage to the skin by ultraviolet rays. Internally, it can lock in skin moisture, prevent moisture from being lost from the epidermis, and maintain skin moisture and proper lipids. Once the skin barrier is damaged, it is easy to cause dryness and desquamation of the skin, and even sensitivity. At the same time, it can induce the occurrence of some inflammatory skin diseases, such as atopic dermatitis, psoriasis, chronic actinic dermatitis, etc. Therefore, it is very important to protect the skin barrier.

[0004] Epidermal barrier function usually refers to the function of the epidermis to prevent excessive water from entering and leaving the body. More and more evidence shows that reduced epidermal permeability barrier function can increase the production of inflammatory cytokines in the epidermis and dermis, Langerhans cells, and mast cells in the dermal tissue. Dermatitis is more likely to occur after skin irritation. At the same time, damage to the epidermal permeability barrier function promotes bacterial colonization of the skin, and reduced epidermal permeability barrier function is at least related to the occurrence and development of atopic dermatitis and psoriasis. Using safe skin care products that have all-round improvement of epidermal function can help prevent and treat certain skin and systemic diseases and related mental disorders.

[0005] At present, there are many factors that cause skin barrier damage. In addition to disease factors, environmental factors cannot be ignored. Studies have shown that unhealthy lifestyles and environmental exposures, such as long-term contact with irritants (such as detergents), working in humid environments, and active or passive smoking, can cause abnormal skin lipid metabolism and ultimately lead to impaired skin barrier function.

[0006] The skin barrier includes a microbial barrier (refers to the various microorganisms present on the skin surface forming a micro-ecosystem to resist the invasion of pathogens and enhance skin immunity), a chemical barrier (the pH value on the skin surface is about 4-6, forming an "acidic barrier", mainly composed of acidic substances such as fatty acids and lactic acid, hydrolases and antimicrobial peptides), a physical barrier (keratinized cells and intercellular lipids in the stratum corneum form a brick wall structure, and cells adhere together through cell connections to form a "protective wall") and an immune barrier (Langerhans cells in the epidermis act as "guards" and "sentinels", removing foreign matter and awakening the immune system of the skin). Damage to the skin barrier can induce / aggravate skin problems, such as skin sensitivity symptoms and even skin diseases; and skin diseases, such as skin inflammation, acne, etc., can in turn lead to damage to the skin barrier.

[0007] Sensitive skin is a problematic skin. The characteristics of sensitive skin are: the skin looks thinner and is prone to allergies. There are obvious red blood streaks on the face (dilated capillaries). The skin easily turns red. Generally, the skin turns red and hot when the temperature changes, whether it is too cold or too hot. The skin is easily irritated by environmental factors, seasonal changes and facial care products. It is usually attributed to genetic factors, but more often it is due to the use of hormone cosmetics, which leads to sensitive skin and may be accompanied by skin sensitivity all over the body.

[0008] In addition to genetic factors, the fundamental cause of sensitive skin is that the skin's immunity is reduced due to damage to skin cells, the stratum corneum becomes thinner, and the skin's moisture level is insufficient, which ultimately leads to the skin's barrier function being too weak to resist external stimuli. Then, the skin's nerve fibers are often stimulated by the outside world and become too excited, which easily leads to redness, fever, itching, tingling, rashes and other discomforts.

[0009] At present, for sensitive skin, most skin care products on the market are mainly based on oil moisturizing and hydrating, and use some soothing ingredients, which can objectively relieve skin dryness and inflammation. However, this combination is only a temporary solution and cannot fundamentally solve the problem of sensitive skin. Summary of the invention

[0010] The purpose of the present application is to overcome the deficiencies of the above-mentioned prior art and provide a high-content shea butter all-round repair composition for skin care and its preparation method and application. In view of the decrease in skin immunity due to skin cell damage, the thinning of the stratum corneum leads to insufficient skin moisturization, and ultimately leads to the skin's barrier function being too weak to resist external stimuli, thereby easily causing redness, fever, itching, stinging, rashes and other problems. The high-content shea butter all-round repair composition provided by the present application helps to repair the skin barrier (microbial barrier, chemical barrier, physical barrier and immune barrier) from the root in an all-round way, protects the skin while maintaining the homeostasis of the neuro-endocrine-immune system, and achieves human skin health.

[0011] To achieve the above purpose, the technical solution adopted by this application is:

[0012] The present application provides a high-content shea butter all-round repairing composition for skin care, the composition comprising the following components in percentage by mass:

[0013] Avocado fat 10-30%, avocado oil 0.01-6.99%, avocado fat unsaponifiable matter 0.001-1%, ceramide 0.001-1%, phytosterol oleate 0.01-3%, lactobacillus fermentation product 0.001-1%, amino acid 0.003-7% and bisabolol 0.01-1%.

[0014] The present application adopts avocado butter, avocado oil, avocado butter unsaponifiable matter, ceramide, phytosterol oleate, lactobacillus fermentation product, amino acid and bisabolol to obtain the high-content shea butter allergic repair composition of the present application. The composition does not add artificial synthetic pigments and does not contain 26 kinds of fragrance allergens. The composition can maintain skin moisture, repair the stratum corneum, and maintain the skin barrier function. The brick wall structure of the skin is attached with a sebum film on the surface, which together form a natural protective barrier for the human body, effectively reducing the irritation and impact of the product on sensitive skin. It is gentle and non-irritating, maintains skin moisture, prevents moisture evaporation, and resists external irritation and damage, which is the function of the skin barrier, effectively repairs sensitive skin and inflamed skin, and is suitable for people with all skin types.

[0015] In addition, the composition of the present application can help repair the four major skin barriers (microbial barrier, chemical barrier, physical barrier and immune barrier) in an all-round way, repair the skin barrier from the root, protect the skin while maintaining the homeostasis of the neuro-endocrine-immune systems, and achieve human skin health.

[0016] Among them, avocado tree fat and avocado tree oil are called shea butter. The composition contains more than 10% natural shea butter. Shea butter is closest to the various indicators of human sebum secretion. Shea butter is rich in unsaponifiable matter with anti-inflammatory and repairing properties, and has moisturizing fatty acid triglycerides. It has deep moisturizing and repairing effects on the skin, making the skin absorb more completely the effective ingredients, not only preventing dryness and cracking, but also further restoring and maintaining the natural elasticity of the skin. It has deep moisturizing effects, can promote epidermal cell regeneration, and give the skin nutrition. It can also form a protective barrier on the skin to protect the skin from external irritation and damage.

[0017] The composition of the present application contains lactobacillus fermentation products, which are inactivated lactobacilli, retain the complete cell wall structure of the bacteria, regulate the microecological biological flora, can stimulate the skin to produce antimicrobial peptides, enhance the skin's ability to resist external irritants, and enhance the skin's resistance to pathogenic bacteria.

[0018] The present application adopts a compound of liquid shea butter, plant sterol esters and ceramides to form a bionic sebum film, which fills the "mortar" inside the classic skin brick wall structure of the stratum corneum, plays a physical barrier repair role, thereby enhancing the keratinized cells and intercellular lipids in the stratum corneum to form a brick wall structure. The cells adhere together through cell connections to form a solid "protective wall", which effectively blocks the invasion of harmful external substances and prevents excessive loss of water and nutrients in the body.

[0019] The composition of the present application contains amino acid ingredients. Amino acid is one of the natural moisturizing factors in the skin and is also a basic component of protein. The moisturizer made of amino acid has excellent continuous moisturizing ability, helps to enhance the skin's water retention, prevents the skin from losing water too quickly, and maintains a healthy chemical skin barrier function. By using the above concentration of amino acids, the repair composition can achieve a better moisturizing effect, and the formula cost will not be too high, which is more conducive to the commercialization and marketization of the product.

[0020] The ingredient bisabolol inhibits inflammation internally, enhances the skin's self-immunity ability externally, soothes the skin, reduces inflammatory response, repairs the skin's immune system, and promotes skin repair and healing; the above concentration of bisabolol can show excellent anti-inflammatory and soothing effects.

[0021] The bisabolol and unsaponifiable matter of avocado tree butter in the composition of the present application inhibit inflammation internally, enhance the self-immunity ability externally, soothe the skin, reduce inflammatory response, repair the skin's immune system, and promote skin repair and healing.

[0022] As a preferred embodiment of the high-content shea butter all-round repair composition for skin care described in the present application, the amino acids include 0.001-4% glycine, 0.001-2% serine and 0.001-1% alanine.

[0023] Amino acid is one of the natural moisturizing factors in the skin and is also the basic component of protein. The natural moisturizing factor amino acid components glycine, serine and alanine help enhance the skin's water retention capacity, prevent the skin from losing water too quickly, and maintain a healthy chemical skin barrier function.

[0024] In the skin chemical barrier, filaggrin plays an important role in enhancing the skin barrier function and moisturizing. In the granular layer, in the late stage of keratinocyte differentiation, inactive / insoluble filaggrin precursors are formed. Proteases, such as kallikrein, break it down into free filamentous filaggrin monomers. The role of filaggrin monomers in the stratum corneum: directly bind to keratin, polymerize into keratin bundles, and form the cytoskeleton, the supporting structure of the stratum corneum. It is then degraded into free amino acids and derivatives, such as urocanic acid (UCA) and pyrrolidone carboxylic acid (PCA), namely natural moisturizing factor (NMF).

[0025] As a preferred embodiment of the high-content shea butter all-round repair composition for skin care described in the present application, the composition includes the following components in percentage by mass:

[0026] Avocado fat 10-20%, avocado oil 1-6%, avocado fat unsaponifiable matter 0.1-0.8%, ceramide 0.01-0.5%, phytosterol oleate 0.1-2%, lactobacillus fermentation product 0.05-0.8%, glycine 0.01-2%, serine 0.01-1%, alanine 0.01-0.8% and bisabolol 0.1-0.8%.

[0027] The present application adopts the components in the above-mentioned preferred range, which can better repair and strengthen the four major barrier functions of the skin, resist the invasion of external physical, chemical, biological and other harmful factors, and protect the body from damage.

[0028] The present application adopts the shea butter ingredient with the above-mentioned mass percentage, which is mild and non-irritating, has good air permeability, can be quickly absorbed by the skin, not only has deep moisturizing and high-efficiency moisturizing effects, but also can effectively repair various wounds, dryness, peeling, whitening and sensitivity caused by sunburn and frostbite on the skin; at the same time, the unsaponifiable matter of avocado tree fat also has anti-inflammatory and antioxidant effects, inhibits skin inflammation, enhances self-immunity ability, soothes the skin, promotes skin healing, and anti-aging.

[0029] Preferably, the composition comprises the following components in percentage by mass:

[0030] Avocado butter 15%, avocado oil 5%, avocado butter unsaponifiables 0.5%, ceramide 0.2%, phytosteryl oleate 0.5%, lactobacillus fermentation product 0.5%, glycine 0.5%, serine 0.5%, alanine 0.5% and bisabolol 0.5%.

[0031] When the repair composition adopts the components in the above preferred concentrations, it can better and more effectively repair the four major skin barriers, increase the skin's moisture content and strengthen the skin's barrier function, reduce the stimulation of external substances to the skin, and keep the skin in the best health state at all times.

[0032] According to the product stability experiment, when the shea butter content in the composition exceeds the above concentration range, many problems will occur, such as: the product is not formed, the product has poor absorption, the paste becomes coarse, the odor is abnormal, etc. When the concentration of phytosterol oleate added in the composition exceeds the above concentration range, it is not conducive to the formation of stable bionic sebum, and problems such as product discoloration and abnormal odor are likely to occur.

[0033] Since ceramide has very poor solubility, it is not only insoluble in water, but also soluble in only a very small amount of oil. It is difficult to play a skin care role if it is not well soluble. When the amount added to the formula exceeds the above concentration range, it is difficult to dissolve in the formula, resulting in precipitation during the placement process after emulsification.

[0034] The present application also provides a method for preparing the above-mentioned high-content shea butter all-round repairing composition for skin care, comprising the following steps:

[0035] Avocado butter, avocado oil, avocado butter unsaponifiable matter, ceramide, phytosteryl oleate, lactobacillus fermentation product, amino acid and bisabolol are mixed to obtain a high-content shea butter all-round repairing composition.

[0036] The present application also provides the use of the above-mentioned high-content shea butter all-round repair composition for skin care in the preparation of skin care products.

[0037] As a preferred embodiment of the application described in the present application, the skin care product includes at least one of cream, lotion, essence and gel.

[0038] The present application also provides a skin care product, which includes the high-content shea butter all-round repairing composition for skin care.

[0039] The skin care product provided by the present application contains a high-content shea butter all-round repair composition, has a refreshing feel and can be quickly absorbed by the skin. It not only has a deep moisturizing and high-efficiency moisturizing effect, but also has a repairing effect on skin problems such as dryness and peeling. At the same time, it has a variety of nutrients and antioxidant ingredients required by the skin, improves the epidermal barrier capacity, effectively resists skin aging problems, effectively alleviates skin problems under environmental pressure, improves local microcirculation of the lips, restores normal metabolism, and makes the skin fuller, smoother, more contoured, hydrated and rosy.

[0040] As a preferred embodiment of the skin care product described in the present application, the addition amount of the high-content shea butter all-round repair composition for skin care is 10-35%.

[0041] As a preferred embodiment of the skin care product described in the present application, the skin care product includes at least one of a cream, a body milk, an emulsion, an essence and a gel.

[0042] Preferably, the cream comprises a hand cream or a face cream.

[0043] The preparation of the skin care products described in this application is not limited to product specifications and forms, for example, but not limited to, it can be made into product dosage forms such as creams, body lotions, emulsions, essences, gels, etc.

[0044] This application is based on a high-content shea butter all-round repairing composition, and prepares skin care products with four major skin barrier functions of moisturizing, anti-inflammatory and skin repair by adding other auxiliary materials, including hand creams, face creams, body milks, lotions and other skin care dosage forms.

[0045] As a preferred embodiment of the skin care product described in the present application, the skin care product also includes at least one of 0.5-10% moisturizer, 0.1-0.5% thickener, 0.01-0.4% pH adjuster, 1-10% oil, 0.5-3% surfactant, 0.5-3% fatty alcohol, 0.1-1.0% preservative, and 0.01-0.1% antioxidant.

[0046] As a preferred embodiment of the skin care product described in the present application, the moisturizer includes a polyol (e.g., concentrated glycerin);

[0047] The thickener comprises at least one of xanthan gum, cellulose gum, carbomer and sodium polyacrylate;

[0048] The surfactant includes a nonionic or amphoteric surfactant; the surfactant includes at least one of glyceryl stearate / PEG-100 stearate and polysorbate-60;

[0049] The oil agent includes triethylhexanoin and / or dimethicone.

[0050] The preservative comprises at least one of phenoxyethanol, chlorphenesin, 1,2-hexanediol and chlorphenesin;

[0051] The antioxidant includes at least one of butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and tocopherol.

[0052] The present application also provides a method for preparing the above-mentioned skin care product, comprising the following steps:

[0053] S1, mixing purified water, a thickener and a humectant to obtain an aqueous phase;

[0054] S2, mixing the surfactant, the oil, the avocado fat, the avocado oil, the avocado fat unsaponifiable matter, the phytosteryl oleate, the ceramide, the bisabolol and the antioxidant, heating and stirring to obtain an oil phase;

[0055] S3, adding the oil phase in step S2 to the water phase in step S1 for homogenization and emulsification, and then adding a pH adjuster, a lactobacillus fermentation product, an amino acid and a preservative, mixing and stirring evenly to obtain a skin care product.

[0056] As a preferred embodiment of the method for preparing the skin care product of the present application, in step S2, the heating temperature is 75-85°C;

[0057] In step S3, the homogenization time is 10 to 15 minutes.

[0058] Compared with the prior art, this application has the following beneficial effects:

[0059] The present application provides a high-content shea butter all-round repair composition for skin care, and its preparation method and application. The present application adopts avocado tree fat, avocado tree oil, avocado tree fat unsaponifiable matter, ceramide, phytosterol oleate, lactobacillus fermentation product, amino acid and bisabolol compound, which can repair and strengthen the four major barrier functions of the skin, resist the invasion of external physical, chemical, biological and other harmful factors, and protect the body from damage. The composition can also increase the moisture content of the skin, reduce the stimulation of external substances to the skin, and keep the skin in the best health state at any time.

[0060] Among them, the present application adopts a compound of liquid shea butter, plant sterol esters and ceramides to form a bionic sebum film, which fills the "mortar" inside the classic skin brick wall structure of the stratum corneum, plays a physical barrier repair role, thereby enhancing the keratinized cells and intercellular lipids in the stratum corneum to form a brick wall structure. The cells adhere together through cell connections to form a solid "protective wall", which effectively blocks the invasion of harmful external substances and prevents excessive loss of water and nutrients in the body.

[0061] The composition of the present application contains lactobacillus fermentation products, which are inactivated lactobacilli, retain the complete cell wall structure of the bacteria, regulate the microecological biological flora, can stimulate the skin to produce antimicrobial peptides, enhance the skin's ability to resist external irritants, and enhance the skin's resistance to pathogenic bacteria.

[0062] The bisabolol and unsaponifiable matter of avocado tree butter in the composition of the present application inhibit inflammation internally, enhance the self-immunity ability externally, soothe the skin, reduce inflammatory response, repair the skin's immune system, and promote skin repair and healing. BRIEF DESCRIPTION OF THE DRAWINGS

[0063] Figure 1 This is a graph showing the effects of different repair compositions on skin moisturizing properties in Experimental Example 1;

[0064] Figure 2 The diagram shows the enhancement results of the skin barrier of the cream formula containing the repair composition component of ceramide NP and phytosterol oleate (Example 10) and the cream formula without the repair composition component of ceramide NP and phytosterol oleate (Comparative Example 19) in Experimental Example 3;

[0065] Figure 3 The results of the cream formula containing the repair composition component of the lactobacillus fermentation product (Example 10) and the cream formula without the repair composition component of the lactobacillus fermentation product (Comparative Example 20) in Experimental Example 3 on skin inflammation are shown;

[0066] Figure 4 This is a graph showing the effects of the facial creams prepared in Example 10 and Comparative Example 21 in Experimental Example 3 on skin moisturizing and barrier function;

[0067] Figure 5 This is a result diagram showing the effects of the facial creams of Example 10 and Comparative Example 22 on skin repair in Experimental Example 3;

[0068] Figure 6 This is a graph showing the effect of different concentrations of the repair composition of lactobacillus fermentation product (Example 1, Comparative Example 15) on the relative abundance of Staphylococcus aureus on the skin surface in Experimental Example 3;

[0069] Figure 7The results of the redness fading test using the repair compositions of different concentrations of bisabolol (Example 1, Example 5, Comparative Example 16) in Experimental Example 3;

[0070] Figure 8 This is a graph showing the skin moisturizing test results of the repair compositions of Example 5 and Comparative Example 17 in Test Example 3;

[0071] Fig. 9 This is a graph showing the skin smoothness results of the repair compositions of Example 5 and Comparative Example 17 in Test Example 3;

[0072] Fig.10 This is a graph showing the results of the inhibition of inflammatory enzymes by the repair compositions of Example 5 and Comparative Example 17 in Experimental Example 3;

[0073] Fig.11 This is a graph showing the moisturizing effect of the facial cream product of Example 10 and the facial cream of the blank control group (not containing the repairing composition) for 48 hours in Test Example 3;

[0074] Fig.12 This is the result of the intercellular lipid film length after SDS damage treatment. DETAILED DESCRIPTION

[0075] In order to better illustrate the purpose, technical solutions and advantages of the present application, the present application will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0076] In the following examples and comparative examples, the experimental methods used are conventional methods unless otherwise specified, and the materials, reagents, etc. used are all commercially available unless otherwise specified, and the components and raw materials used in each parallel experiment are of the same type.

[0077] The component information of the high-content shea butter all-round repair composition provided in the following examples and comparative examples is shown in Table 1 (the following components can all be purchased from the chemical or pharmaceutical market).

[0078] Table 1

[0079]

[0080]

[0081] Embodiments 1 to 5: A high-content shea butter all-round repairing composition for skin care

[0082] Examples 1 to 5 provide a high-content shea butter all-round repairing composition for skin care, and the formula thereof is shown in Table 1 (mass percentage content).

[0083] The preparation method of the high-content shea butter all-round repairing composition for skin care comprises the following steps:

[0084] Avocado butter, avocado oil, avocado butter unsaponifiable matter, ceramide, phytosteryl oleate, lactobacillus fermentation product, amino acid and bisabolol are mixed to obtain a high-content shea butter all-round repairing composition.

[0085] Table 1

[0086]

[0087] Comparative Examples 1 to 17

[0088] Comparative Examples 1 to 17 provide a high-content shea butter all-round repairing composition for skin care, and the formula thereof is shown in Table 2 (mass percentage).

[0089] The preparation methods of the high-content shea butter all-round repairing compositions provided in Comparative Examples 1 to 17 are similar to those of the repairing compositions of Examples 1 to 5.

[0090] Table 2

[0091]

[0092] Embodiments 6 to 10: A moisturizing and repairing facial cream and a preparation method thereof

[0093] The formulas of the moisturizing repairing creams provided in Examples 6 to 10 are shown in Table 3.

[0094] The moisturizing and repairing facial creams provided in Examples 6 to 10 respectively use the repairing compositions prepared in Examples 1 to 5.

[0095] The preparation method of the moisturizing and repairing facial cream provided in this embodiment comprises the following steps:

[0096] 1. Instrument disinfection: First, wash the instruments including the reactor with 80℃-100℃ sterile water, then rinse with 75% disinfectant alcohol, and blow dry with cold air;

[0097] 2. Water phase preparation: Add the formulated amount of purified water, disodium EDTA, carbomer, and concentrated glycerin to the reactor, start stirring, stir to ensure uniform dispersion without particles, heat to 75-85°C, and keep warm;

[0098] 3. Oil phase preparation: Add the formulated amount of surfactant (glyceryl stearate / PEG-100 stearate and polysorbate-60, mass ratio is 1:1), oil (polydimethylsiloxane), cetyl alcohol, shea butter, phytosteryl oleate, ceramide, bisabolol and antioxidant (butylated hydroxytoluene) in the repair composition to the side reaction kettle, start heating, start stirring, heat to 75-85°C, and ensure that it is completely dissolved into a transparent liquid;

[0099] 4. Adding materials: Start stirring and heat preservation of the reactor, slowly pump the oil phase from the secondary reactor into the reactor, and start high-speed homogenization and emulsification. After the oil phase is completely added, keep warm and homogenize for 10 to 15 minutes to ensure complete and uniform emulsification. Stop homogenization, maintain stirring and start cooling to 55°C, add pH regulator, continue stirring and start cooling to 40°C, add other ingredients in the repair composition, lactobacillus fermentation product, arginine, serine and alanine, preservatives (phenoxyethanol / ethylhexylglycerin, ratio of 9:1) and essence, and stir to ensure uniform mixing;

[0100] 5. Cool down to room temperature and the mixing is completed;

[0101] 6. Quality inspection and filling: After cooling to room temperature, check and fill after passing the inspection to obtain the moisturizing and repairing facial cream.

[0102] Table 3

[0103]

[0104] Comparative Examples 18 to 34

[0105] Compared with Example 10, Comparative Examples 18 to 34 provide a moisturizing repairing facial cream, the difference being that the repairing composition is different, and the remaining contents and preparation methods are the same as those of Example 6.

[0106] Compared with Example 6, Comparative Examples 18 to 34 respectively use the repair compositions of Comparative Examples 1 to 17.

[0107] Embodiments 11 to 15: A moisturizing and repairing hand cream and its preparation method

[0108] The formulas of the moisturizing and repairing hand creams provided in Examples 11 to 15 are shown in Table 4.

[0109] The moisturizing and repairing hand creams provided in Examples 11 to 15 respectively use the repairing compositions prepared in Examples 1 to 5.

[0110] The preparation method of the moisturizing and repairing hand cream provided in this embodiment comprises the following steps:

[0111] 1. Instrument disinfection: First, wash the instruments including the reactor with 80℃-100℃ sterile water, then rinse with 75% disinfectant alcohol, and blow dry with cold air;

[0112] 2. Water phase preparation: Add the formulated amount of purified water, disodium EDTA, thickener carbomer, and concentrated glycerin to the reactor, start stirring, stir to ensure uniform dispersion without particles, heat to 75-85°C, and keep warm;

[0113] 3. Oil phase preparation: Add the formulated amount of surfactant (glyceryl stearate / PEG-100 stearate and polysorbate-60, mass ratio is 1:1), oil (glyceryl tri(ethylhexanoate) ester and polydimethylsiloxane), higher fatty alcohol (cetyl alcohol), shea butter, phytosteryl oleate, ceramide, bisabolol and antioxidant (butylated hydroxytoluene) in the repair composition to the side reaction kettle, start heating, start stirring, heat to 75-85°C, and ensure that it is completely dissolved into a transparent liquid;

[0114] 4. Adding materials: Start stirring and heat preservation of the reactor, slowly pump the oil phase from the secondary reactor into the reactor, and start high-speed homogenization and emulsification. After the oil phase is completely added, keep warm and homogenize for 10 to 15 minutes to ensure complete and uniform emulsification. Stop homogenization, maintain stirring and start cooling to 55°C, add pH regulator (triethanolamine), continue stirring and start cooling to 40°C, add other ingredients in the repair composition, lactobacillus fermentation product, arginine, serine and alanine, preservative (phenoxyethanol / ethylhexylglycerin, ratio of 9:1) and essence, and stir to ensure uniform mixing;

[0115] 5. Cool down to room temperature and the mixing is completed;

[0116] 6. Quality inspection and filling: After cooling to room temperature, check and fill after passing the inspection to obtain the moisturizing and repairing hand cream.

[0117] Table 4

[0118]

[0119]

[0120] Comparative Examples 35 to 43

[0121] Compared with Example 11, Comparative Examples 35 to 43 provide a moisturizing repairing hand cream, the difference being that the repairing composition is different, and the remaining contents and preparation methods are the same as those of Example 7.

[0122] Compared with Example 11, Comparative Examples 35 to 43 respectively use the repair compositions of Comparative Examples 6 to 14.

[0123] Embodiments 16 to 20: A moisturizing and repairing body lotion and its preparation method

[0124] The formulas of the moisturizing and repairing body lotions provided in Examples 16 to 20 are shown in Table 5.

[0125] The moisturizing and repairing body lotions provided in Examples 16 to 20 respectively use the repairing compositions prepared in Examples 1 to 5.

[0126] The method for preparing the moisturizing and repairing body lotion provided in the embodiment comprises the following steps:

[0127] 1. Instrument disinfection: First, wash the instruments including the reactor with 80℃-100℃ sterile water, then rinse with 75% disinfectant alcohol and blow dry with cold air;

[0128] 2. Water phase preparation: Add the formulated amount of purified water, disodium EDTA, carbomer, and concentrated glycerin to the reactor, start stirring, stir to ensure uniform dispersion without particles, heat to 75-85°C, and keep warm;

[0129] 3. Oil phase preparation: Add the formulated amount of surfactant (glyceryl stearate / PEG-100 stearate and polysorbate-60, mass ratio is 1:1), oil agent (polydimethylsiloxane), shea butter, phytosteryl oleate, ceramide, bisabolol and antioxidant (butylated hydroxytoluene) in the repair composition to the side reaction kettle, start heating, start stirring, heat to 75-85°C, and ensure that it is completely dissolved into a transparent liquid;

[0130] 4. Adding materials: Start stirring and heat preservation of the reactor, slowly pump the oil phase from the secondary reactor into the reactor, and start high-speed homogenization and emulsification. After the oil phase is completely added, keep warm and homogenize for 10 to 15 minutes to ensure complete and uniform emulsification. Stop homogenization, maintain stirring and start cooling to 55°C, add pH regulator (triethanolamine), continue stirring and start cooling to 40°C, add other ingredients in the repair composition, lactobacillus fermentation product, arginine, serine and alanine, preservatives (phenoxyethanol / ethylhexylglycerin) and essence, and stir to ensure uniform mixing;

[0131] 5. Cool down to room temperature and the mixing is completed;

[0132] 6. Quality inspection and filling: After cooling to room temperature, check and fill after passing the inspection to obtain the moisturizing and repairing body lotion.

[0133] Table 5

[0134]

[0135]

[0136] Comparative Examples 44 to 52

[0137] Compared with Example 17, Comparative Examples 44 to 52 provide a moisturizing and repairing body lotion, the difference being that the repairing composition is different, and the remaining contents and preparation methods are the same as those of Example 8.

[0138] Compared with Example 17, Comparative Examples 44 to 52 respectively use the repair compositions of Comparative Examples 6 to 14.

[0139] Experimental Example 1: Effects of different repair compositions on skin moisturizing properties

[0140] After applying the repair composition (Examples 1-5, Comparative Examples 1-5, Comparative Examples 15-17) to the test area of ​​the test subject, the transepidermal water loss and skin moisture retention of the area were measured every hour for a total of 4 hours. Background measurements were taken before and after cleaning with alcohol. The Courage+Khazaka MPA5 system equipped with a Tewameter 300 and CorneometerCM 825 probe was used for evaluation. The data was read when the signal was stable and the average of at least 20 readings was used as the measurement value. The results are shown in Table 6.

[0141] Test process:

[0142] 1. Test site: hand skin;

[0143] 2. Test time: 4 hours;

[0144] 3. Before and after using alcohol to cleanse the test product, take an appropriate amount on the palm of your hand and gently pat the skin until it is completely absorbed;

[0145] 4. Experimental participants: 20 females, aged 20-55 years old;

[0146] 5. Test process: 1) One week before the test, the subjects stop using the composition with moisturizing effect on the test area; 2) The subjects sign the informed consent after listening to the test instructions on site; 3) The subjects visit the laboratory, clean their faces with clean water, and dry them with dandruff-free absorbent paper towels, and sit in a constant temperature and humidity room for 30 minutes. They are not allowed to drink water or beverages during this period, and the subjects must remain relaxed; 4) Test: After applying the repair composition, the transepidermal water loss and skin moisturizing degree of the area are measured every hour for a total of 4 hours; 5) Organize the data and issue a report.

[0147] As expected, the TEWL of the test area that was scrubbed with alcohol increased immediately. The TEWL of the area that was treated with the shea butter repair composition returned to its initial value about 2 hours after application. After 3 to 4 hours, the moisture barrier was further enhanced and the TEWL decreased further.

[0148] In contrast, the repair composition without shea butter (Comparative Example 1) did not show the phenomenon of rapid recovery of transepidermal water loss as shea butter did.

[0149] The use of a repair composition containing shea butter (Example 5) can improve the moisture retention of the skin, as shown in the measurement results after 1 hour of use, and its moisturizing effect is long-lasting during the 4-hour test period. The composition without shea butter has a poorer effect on improving the moisture measurement value (such as Figure 1). The results of these two different tests show that the moisturizing and humectant properties of the shea butter repair composition decreased to varying degrees when shea butter was missing.

[0150] Table 6 Moisture Test

[0151]

[0152] Experimental Example 2: Effects of different repair compositions on skin barrier function

[0153] Test instrument: Vapometer transepidermal water loss measuring instrument (produced by Delfin Technologies). Read the data when the signal is stable, and take the average value of at least 20 readings as the measured value.

[0154] 1. Experimental test: Test the effects of the repair compositions of Examples 1 to 5 and Comparative Examples 1 to 5 and Comparative Examples 15 to 17 on the skin barrier function.

[0155] Test process:

[0156] 1. Test site: facial skin;

[0157] 2. Test time: 0 hours, 4 hours;

[0158] 3. Use of test product: Clean hands with water and dry with a non-chip absorbent paper towel. Apply an appropriate amount on the palm of your hand and gently pat the skin until it is completely absorbed;

[0159] 4. Experimental participants: 20 females, aged 20-55 years old;

[0160] 5. Test process:

[0161] 1) One week before the test, the test subject stopped using the repair composition with moisturizing effect on the test area;

[0162] 2) The subjects signed the informed consent form after listening to the trial description on site;

[0163] 3) When the subjects come to the laboratory, they clean their faces with clean water and dry them with a dandruff-free absorbent paper towel. They sit in a constant temperature and humidity room for 30 minutes without drinking water or beverages and must remain relaxed.

[0164] 4) Test: Clean the face with clean water and dry it with a non-chip absorbent paper towel. After applying the repair composition,

[0165] The skin TEWL value of the skin at this time is measured by an instrument as the comparison data of T0, and then the repair composition is applied; after 4 hours, the transepidermal water loss of the area is measured as the T4 data;

[0166] 5) Organize data and issue reports.

[0167] The results are shown in Table 7.

[0168] Table 7

[0169]

[0170] Test Example 3: Effects of Products Containing Different Repair Compositions on Skin

[0171] 1. In this experiment, a cream formula containing a repair composition component of ceramide NP and phytosterol oleate (Example 10) and a cream formula containing no repair composition component of ceramide NP and phytosterol oleate (Comparative Example 19) were compared to test the enhancement effect on the skin barrier.

[0172] The results showed that the use of the cream containing the repair composition of ceramide NP and phytosteryl oleate for 6 days increased the epidermal thickness by more than 50% compared with the cream without the repair composition of ceramide NP and phytosteryl oleate. Figure 2 shown.

[0173] 2. This experiment also compared the repair composition ingredients of the cream formula containing lactobacillus fermentation products (Example 10) and the repair composition ingredients of the cream formula without lactobacillus fermentation products (Comparative Example 20), and compared the effects on skin inflammation.

[0174] Lactobacillus fermentation products are inactivated lactobacilli that retain the complete cell wall structure of the bacteria. They can regulate the microecological flora, stimulate the skin to produce antimicrobial peptides, enhance the skin's microecological barrier function, and reduce skin inflammation.

[0175] The results showed that the skin inflammatory factor IL-8 (produced by IL-1α or Staphylococcus aureus) was reduced by 45% when the cream containing the repair composition of lactobacillus fermentation products was used compared with the cream without the repair composition of lactobacillus fermentation products. Figure 3 shown.

[0176] 3. This experiment also compares the effects of the creams prepared in Example 10 and Comparative Example 21 on the skin's moisturizing and barrier functions. The repair composition containing glycine, serine and alanine (Example 10) can stimulate the production of filaggrin and enhance the skin's moisturizing and barrier functions, such as Figure 4 shown.

[0177] 4. This experiment also compared the effects of the creams of Example 10 and Comparative Example 22 on skin repair.

[0178] Redness Removal and Soothing Test:

[0179] Instrument: VISIA CR (Canfield Scientific)

[0180] Samples: A1 (repairing composition cream, Example 6); A2 (repairing composition cream without bisabolol, Comparative Example 22);

[0181] Methods: 30 subjects used two samples twice a day using the half-face control method, with sample A1 and sample A2 used on the left and right halves of the face, once in the morning and once in the evening. VISIA CR was used to take high-resolution frontal images before use and 0.5h, 1h, 3h, 24h, 3 days, and 7 days after use, and IPP software was used to analyze the erythema.

[0182] The results show that the repair composition containing bisabolol can effectively reduce facial erythema and soothe sensitive skin, and the effect is significantly better than the repair composition without bisabolol. Figure 5 shown.

[0183] 5. This experiment also compared the effects of repair compositions containing different concentrations of lactobacillus fermentation products (Example 1, Comparative Example 15) on the relative abundance of Staphylococcus aureus on the skin surface.

[0184] Lactobacillus fermentation products, by regulating the microecological flora, stimulate the skin to produce antimicrobial peptides, enhance the microecological barrier function of the skin, thereby enhancing the skin's ability to resist external stimuli and enhance the skin's resistance to pathogens. However, the biological flora of human skin is relatively balanced. Only when probiotics and harmful bacteria are in a balanced state can it be beneficial to skin health. If probiotics or harmful bacteria are too strong, they will break the microecological balance of the skin, thereby causing an imbalance in the microecological barrier. Through testing, the skin care effect of 0.1-1.0% concentration of lactobacillus fermentation products, the abundance of Staphylococcus epidermidis in the skin: the initial concentration increased by 20%. When the concentration of lactobacillus fermentation products continued to increase, the concentration of Staphylococcus epidermidis in the skin decreased to the initial state, indicating that the higher the concentration of this substance is, the more beneficial it is to the skin. Figure 6 shown.

[0185] 6. This experiment also compared the repair compositions using different concentrations of bisabolol (Example 1, Example 5, Comparative Example 16) and conducted a redness fading test.

[0186] The test results clearly show that 0.5% of bisabolol has the best red-fading effect, and 1.0% of bisabolol has a red-fading effect of 68%. However, when the concentration of bisabolol exceeds 1.0%, the red-fading effect is not significantly different from the blank control. Figure 7 shown.

[0187] 7. This experiment also compared the moisturizing and repairing effects of the repair compositions of Example 5 and Comparative Example 17.

[0188] For the convenience of comparison, the repair composition is marked as sample A, and the composition using olive oil as a parallel replacement is marked as sample B. The test results show that after the avocado oil is replaced, the moisturizing power, skin smoothness and anti-inflammatory power are all reduced. Figures 8 to 10 .

[0189] 8. The present application also compares the moisturizing power of the facial cream product of Example 10 and the facial cream of the blank control group (not containing the repairing composition) for 48 hours (using the skin moisture measuring instrument Corneometer CM825). The facial cream of Example 10 has excellent moisturizing and skin repairing effects, such as Fig.11 shown.

[0190] 9. In vitro experiment: Repair of intercellular lipid membrane.

[0191] Experimental steps: After the in vitro skin cells were damaged with SDS (sodium dodecyl sulfate) for 24 hours, the cell samples that had been damaged by SDS and repaired with moisturizing cream were fixed, dehydrated, embedded, and made into ultra-thin slices. They were then placed in an electron microscope and observed and photographed at a suitable magnification. The appropriate area was selected from the captured image, and the length of the intercellular lipid film was measured using image analysis software.

[0192] The results are as follows Fig.12 As shown. After 24h of SDS damage treatment, the moisturizing repair cream was able to regenerate the intercellular lipid membrane structure of the 3D reconstruction model of healthy skin.

[0193] Test Example 4: Comparison of product performance

[0194] 1. Compare the performances of the facial cream product of Example 10, the hand cream product of Example 11, the body lotion product of Example 17, the facial cream products of Comparative Examples 23 to 25, the hand cream products of Comparative Examples 35 to 37, and the body lotion products of Comparative Examples 44 to 46.

[0195] The results are shown in Table 8.

[0196] Table 8

[0197]

[0198]

[0199] As shown in Table 8, when the shea butter content in the repair composition exceeds 30%, more problems will occur, such as: the product is not formed, the product has poor absorption, the paste becomes coarse, the odor is abnormal, etc. The following is a comparative test of shea butter of different concentrations.

[0200] 2. Compare the shelf stability of the face cream product of Example 10, the hand cream product of Example 11, the body lotion product of Example 17, the face cream products of Comparative Examples 26 to 28, the hand cream products of Comparative Examples 38 to 40, and the body lotion products of Comparative Examples 47 to 49.

[0201] The results are shown in Table 9.

[0202] Table 9

[0203]

[0204] Phytosterol oleate belongs to plant sterols, and its structure and function are similar to cholesterol. Cholesterol is an important component of skin barrier health, forming intercellular lipids. Intercellular lipids and keratinocytes form a natural skin barrier to prevent skin moisture loss and resist external damage. When the concentration of phytosterol oleate added exceeds 3%, it is not conducive to the formation of stable bionic sebum, and it is easy to have problems such as product discoloration and abnormal odor. The results are shown in Table 9.

[0205] 3. Compare the stability of the face cream product of Example 10, the hand cream product of Example 11, the body lotion product of Example 17, the face cream products of Comparative Examples 29 to 31, the hand cream products of Comparative Examples 41 to 43, and the body lotion products of Comparative Examples 50 to 52. The results are shown in Table 10.

[0206] Table 10

[0207] Group Stable performance Facial cream product (Example 10) Completely dissolved, no abnormal precipitation was found in the stability test Facial cream product (Comparative Example 29) Completely dissolved, no abnormal precipitation was found in the stability test Facial cream product (Comparative Example 30) Completely dissolved, but abnormal precipitation was found in stability test Facial cream product (Comparative Example 31) Cannot be completely dissolved and emulsified Hand cream product (Example 11) Completely dissolved, no abnormal precipitation was found in the stability test Hand cream product (Comparative Example 29) Completely dissolved, no abnormal precipitation was found in the stability test Hand cream product (Comparative Example 30) Completely dissolved, but abnormal precipitation was found in stability test Hand cream product (Comparative Example 31) Cannot be completely dissolved and emulsified Body lotion product (Example 17) Completely dissolved, no abnormal precipitation was found in the stability test Body lotion product (Comparative Example 50) Completely dissolved, no abnormal precipitation was found in the stability test Body lotion product (Comparative Example 51) Completely dissolved, but abnormal precipitation was found in stability test Body lotion product (Comparative Example 52) Cannot be completely dissolved and emulsified

[0208] Ceramide is a type of amide compound formed by dehydration of long-chain fatty acids and the amino group of sphingosine. It mainly includes ceramide phosphorylcholine and ceramide phosphorylethanolamine. Phospholipids are the main components of cell membranes. 40% to 50% of sebum in the stratum corneum is composed of ceramide. Ceramide is the main part of the intercellular matrix and plays an important role in maintaining the balance of moisture in the stratum corneum. Ceramide has a strong ability to associate with water molecules. It maintains skin moisture by forming a network structure in the stratum corneum. Therefore, ceramide has the function of maintaining skin moisture.

[0209] However, ceramide has very poor solubility. Not only is it insoluble in water, but it is also soluble in only a very small amount of oil. It is difficult to play a skin care role if it is not well soluble. When the amount added to the formula exceeds 1%, it is difficult to dissolve in the formula, resulting in precipitation during the standing process after emulsification.

[0210] The present application provides a high-content shea butter all-round repair composition for skin care, as well as a preparation method and application thereof. The present application adopts avocado tree fat, avocado tree oil, avocado tree fat unsaponifiable matter, ceramide, phytosterol oleate, lactobacillus fermentation product, amino acid and bisabolol to repair and strengthen the four major barrier functions of the skin, resist the invasion of external physical, chemical, biological and other harmful factors, protect the body from damage, increase the skin's moisture content and strengthen the skin's barrier function, reduce the stimulation of external substances to the skin, and keep the skin in the best health state at any time.

[0211] The main component of the application, natural plant oil shea butter, has a particularly outstanding moisturizing and repairing effect on the skin. The main components of shea butter (shea butter, shea oil) are triglycerides (containing a certain amount of linoleic acid) and unsaponifiable matter, wherein the triglyceride content is about 80%, and the plant triglyceride component is very balanced, with a high oleic acid ratio (40-70%) with high moisturizing degree, and a certain proportion of Omega-6 fatty acids (linolenic acid), which can provide essential fatty acids for the skin, and have deep moisturizing and efficient moisturizing effects; and the content of unsaponifiable matter varies according to the season, origin, extraction and refining methods, especially the triterpenoids containing cinnamate, which have an absorption effect on UVB, effectively resist UV inflammation damage and skin problems caused by the environment, and are a natural sunscreen ingredient, and can also promote and protect the production of collagen and delay aging.

[0212] The present application also contains ceramide NP and phytosteryl oleate, which are combined with shea butter to form a bionic sebum film, filling the "mortar" inside the classic skin brick wall structure of the stratum corneum, and playing a physical barrier repair role, thereby enhancing the keratinized cells and intercellular lipids in the stratum corneum to form a brick wall structure. The cells adhere together through cell connections to form a solid "protective wall", which together form a natural protective barrier for the human body, maintain skin moisture, prevent moisture evaporation, resist external stimuli and damage, effectively block the invasion of harmful external substances, and prevent excessive loss of water and nutrients in the body.

[0213] The present application also contains an ingredient, lactobacillus fermentation product, which is an inactivated lactobacillus that retains the complete cell wall structure of the bacteria, can regulate the microecological flora, can stimulate the skin to produce antimicrobial peptides, and enhance the skin's microecological barrier function, thereby enhancing the skin's ability to resist external irritants and enhancing the skin's resistance to pathogenic bacteria.

[0214] The present application also contains natural moisturizing factor amino acid components glycine, serine and alanine. Amino acid is one of the natural moisturizing factors in the skin and is also the basic component of protein. Moisturizers made from amino acids have excellent continuous moisturizing ability, help enhance the skin's water retention, prevent the skin from losing water too quickly, and maintain a healthy chemical skin barrier function;

[0215] This application also contains bisabolol ingredients and natural shea butter unsaponifiable matter, which can inhibit inflammation internally, enhance self-immunity ability externally, soothe the skin, reduce inflammatory response, repair the skin's immune system, and promote skin repair and healing.

[0216] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present application rather than to limit the scope of protection of the present application. Although the present application has been described in detail with reference to the preferred embodiments, ordinary technicians in this field should understand that the technical solution of the present application can be modified or replaced by equivalents without departing from the essence and scope of the technical solution of the present application.

Claims

1. A high-content shea butter all-round repair composition for skin care, characterized in that: The composition includes the following components in percentage by mass: Avocado fat 10-30%, avocado oil 0.01-6.99%, avocado fat unsaponifiable matter 0.001-1%, ceramide 0.001-1%, phytosterol oleate 0.01-3%, lactobacillus fermentation product 0.001-1%, amino acid 0.003-7% and bisabolol 0.01-1%.

2. The high-content shea butter all-round repair composition for skin care according to claim 1, characterized in that: The amino acids include 0.001-4% glycine, 0.001-2% serine and 0.001-1% alanine.

3. The high-content shea butter all-round repair composition for skin care according to claim 1 or 2, characterized in that: The composition includes the following components in percentage by mass: Avocado fat 10-20%, avocado oil 1-6%, avocado fat unsaponifiable matter 0.1-0.8%, ceramide 0.01-0.5%, phytosterol oleate 0.1-2%, lactobacillus fermentation product 0.05-0.8%, glycine 0.01-2%, serine 0.01-1%, alanine 0.01-0.8% and bisabolol 0.1-0.8%.

4. The method for preparing the high-content shea butter all-round repair composition for skin care according to any one of claims 1 to 3, characterized in that: The following steps are involved: Avocado butter, avocado oil, avocado butter unsaponifiable matter, ceramide, phytosteryl oleate, lactobacillus fermentation product, amino acid and bisabolol are mixed to obtain a high-content shea butter all-round repairing composition.

5. Use of the high-content shea butter all-round repairing composition for skin care as claimed in any one of claims 1 to 3 in the preparation of skin care products.

6. The use according to claim 5, characterized in that The skin care product includes at least one of a cream, a body milk, a lotion, an essence and a gel.

7. A skin care product, characterized in that: The skin care product comprises the high-content shea butter all-round repairing composition for skin care as claimed in any one of claims 1 to 3.

8. The skin care product according to claim 7, characterized in that The addition amount of the high-content shea butter all-round repairing composition for skin care is 10-35%.

9. The skin care product according to claim 7, characterized in that: The skin care product includes at least one of cream, lotion, essence and gel.

10. The skin care product according to claim 7, characterized in that The skin care product also includes at least one of 0.5-10% moisturizer, 0.1-0.5% thickener, 0.01-0.4% pH adjuster, 1-10% oil, 0.5-3% surfactant, 0.5-3% fatty alcohol, 0.1-1.0% preservative, and 0.01-0.1% antioxidant.

11. The skin care product according to claim 10, characterized in that The humectant includes a polyol; The thickener comprises at least one of xanthan gum, cellulose gum, carbomer and sodium polyacrylate; The surfactant includes a nonionic or anionic surfactant; The preservative comprises at least one of phenoxyethanol, ethylhexylglycerin, chlorphenesin, 1,2-hexanediol and chlorphenesin; The antioxidant includes at least one of butylated hydroxytoluene, butylated hydroxyanisole, dibutylated hydroxytoluene, tert-butylhydroquinone and tocopherol.

12. A method for preparing a skin care product according to claim 10, characterized in that: The preparation method of the skin care product comprises the following steps: S1, mixing purified water, a thickener and a humectant to obtain an aqueous phase; S2, mixing the surfactant, the oil, the avocado fat, the avocado oil, the avocado fat unsaponifiable matter, the phytosteryl oleate, the ceramide, the bisabolol and the antioxidant, heating and stirring to obtain an oil phase; S3, adding the oil phase in step S2 to the water phase in step S1 for homogenization and emulsification, and then adding a pH adjuster, a lactobacillus fermentation product, an amino acid and a preservative, mixing and stirring evenly to obtain a skin care product.

13. The method for preparing a skin care product according to claim 12, characterized in that: In step S2, the heating temperature is 75-85°C; In step S3, the homogenization time is 10 to 15 minutes.

Citation Information

Patent Citations

  • Lip care product with high content of shea butter and preparation method of lip care product

    CN106902027A

  • Cream for sensitive skin and preparation method of cream

    CN107049903A

  • Full-effect shea butter sensitive skin repairing emulsion as well as preparation method and application thereof

    CN113749986A

  • Skin Anti-ageing composition

    WO2024251835A1