Boa oil eye cream with eye wrinkle fading and wrinkle removing effects and preparation method of boa oil eye cream

By using eye creams with ingredients such as python oil, the elastase activity is inhibited, and the problems of wrinkles and aging around the eyes are solved, and the effect of lightening crow's feet and fine lines is achieved to improve skin elasticity and moisture.

CN119970568APending Publication Date: 2025-05-13HAINAN G&P PYTHON TECH CO LTD
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Patent Information

Application Number
CN202510394298.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-31
Publication Date
2025-05-13

AI Technical Summary

Technical Problem

Due to the increased elastase activity of the skin around the eyes, the crow's feet and fine lines are produced, and the self-healing ability is limited, making it difficult to effectively resist wrinkles and anti-aging.

Method used

Eye cream using python oil, pyramid and hawthorn extract, hydrolyzed β-glucan, dog teeth rose fruit oil, hydrolyzed oil olive leaf extract, sophora root extract, European red pine cone extract, Kerry Kelp extract and myrrh leaf cell extract, etc., to reduce the effect of crow's feet and fine lines around the eyes by inhibiting the activity of elastase.

Benefits of technology

Effectively inhibit elastase activity, desalinate crow's feet and fine lines around the eyes, achieve good anti-wrinkle and anti-aging effects, and improve skin elasticity and moisture content.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention provides boa oil eye cream with eye wrinkle fading and wrinkle removing effects and a preparation method of the boa oil eye cream. Comprising the following components in parts by weight: 10-20 parts of boa oil, 2-5 parts of a traditional Chinese medicine extracting solution, 2-5 parts of hydrolyzed beta-glucan, 10-15 parts of rosa canina fruit oil, 1-3 parts of a hydrolyzed olive leaf extract, 1-3 parts of a radix sophorae flavescentis extract, 5-15 parts of an European red pine cone fruit extract, 0.3-0.6 part of a Klarch kelp extract and 0.3-0.6 part of a myrrh leaf cell extract. The traditional Chinese medicine extracting solution is prepared from polygonatum odoratum and hawthorn. The boa oil eye cream capable of effectively inhibiting the activity of elastinase can effectively achieve the effects of fading crow's feet, fine wrinkles and the like around eyes, reduce wrinkles, fine wrinkles and the like, achieve good anti-wrinkle and anti-aging effects and solve the problem of skin aging caused by internal and external factors.
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Description

Technical Field

[0001] The invention relates to the technical field of daily chemical products, and in particular to a python oil eye cream with eye wrinkle and lightening effects and a preparation method thereof. Background Art

[0002] The skin has many important functions, such as barrier function and temperature regulation. As we age, the body's antioxidant system gradually decreases, which damages the skin's barrier function. At the same time, external stimuli such as electromagnetic radiation, strong light, and chemicals further aggravate skin damage, trigger inflammation, photoaging, and other reactions, and ultimately lead to rapid skin aging. Under the combined effects of aging and external stimuli, the amount of collagen and elastic fibers in the skin decreases, which in turn causes skin wrinkles. Active substances with antioxidant and anti-wrinkle effects are crucial to combat skin aging. Anti-wrinkle can reduce skin wrinkles and sagging, allowing the skin to better resist various external stimuli and reduce the occurrence of skin allergies, dryness, and other problems. The use of anti-wrinkle ingredients can also help promote the production of skin collagen and elastin, keeping the skin smooth, firm, and elastic.

[0003] Elastase is an enzyme that can degrade elastin. Studies have shown that elastase is positively correlated with aging, and the degradation of elastin by enzymes is very serious in the skin of the elderly. By inhibiting the activity of elastase, it helps to maintain the elasticity of the skin and reduce the formation of wrinkles. The skin around the eyes is one of the thinnest skins in the human body, and there are fewer sebaceous glands and sweat glands around the eyes, which makes the barrier function of the skin around the eyes relatively weak, and water is more easily lost. The skin around the eyes is also more susceptible to various external stimuli and injuries. In addition, the metabolism rate of the skin around the eyes is slow and the self-repair ability is limited. Therefore, in order to cope with the problems such as the reduction of elastin around the eyes, a skin care product that can effectively inhibit the activity of elastase is urgently needed to reduce the formation of crow's feet and fine lines around the eyes. Summary of the invention

[0004] In view of this, the purpose of the present invention is to propose a python oil eye cream with eye line lightening and wrinkle removal effects and a preparation method thereof, to provide a python oil eye cream that effectively inhibits the activity of elastase, to achieve the purpose of lightening crow's feet and fine lines around the eyes, to achieve good anti-wrinkle and anti-aging effects, and to effectively solve the skin aging problem caused by internal and external factors.

[0005] The technical solution of the present invention is achieved in this way:

[0006] A python oil eye cream with eye wrinkle and line lightening effects, comprising the following components by weight: 10-20 parts of python oil, 2-5 parts of Chinese medicine extract, 2-5 parts of hydrolyzed β-glucan, 10-15 parts of dog rose fruit oil, 1-3 parts of hydrolyzed olive leaf extract, 1-3 parts of sophora flavescens root extract, 5-15 parts of European red pine cone extract, 0.3-0.6 parts of Laminaria japonica extract and 0.3-0.6 parts of myrrh leaf cell extract;

[0007] The traditional Chinese medicine extract is prepared from polygonatum odoratum and hawthorn.

[0008] Preferably, the composition comprises the following components in parts by weight: 10-15 parts of python oil, 2-4 parts of traditional Chinese medicine extract, 2-3 parts of hydrolyzed β-glucan, 10-15 parts of dog rose fruit oil, 1-2 parts of hydrolyzed olive leaf extract, 1-3 parts of Sophora flavescens root extract, 8-15 parts of European red pine cone extract, 0.4-0.6 parts of Laminaria japonica extract and 0.4-0.6 parts of Commiphora myrrha leaf cell extract.

[0009] More preferably, the composition comprises the following components by weight: 10 parts of python oil, 2 parts of Chinese medicine extract, 2 parts of hydrolyzed β-glucan, 15 parts of dog rose fruit oil, 2 parts of hydrolyzed olive leaf extract, 3 parts of Sophora flavescens root extract, 10 parts of European red pine cone extract, 0.5 parts of Laminaria japonica extract and 0.5 parts of Commiphora myrrha leaf cell extract;

[0010] Or, in parts by weight, comprising the following components: 10 parts of python oil, 4 parts of Chinese medicine extract, 2 parts of hydrolyzed β-glucan, 10 parts of dog rose fruit oil, 1 part of hydrolyzed olive leaf extract, 1 part of Sophora flavescens root extract, 15 parts of European red pine cone extract, 0.5 parts of Laminaria japonica extract and 0.5 parts of Commiphora myrrha leaf cell extract;

[0011] Or, in parts by weight, it includes the following components: 15 parts of python oil, 2 parts of traditional Chinese medicine extract, 2 parts of hydrolyzed β-glucan, 10 parts of dog rose fruit oil, 2 parts of hydrolyzed olive leaf extract, 3 parts of Sophora flavescens root extract, 8 parts of European red pine cone extract, 0.5 parts of Laminaria japonica extract and 0.5 parts of Myrrha leaf cell extract.

[0012] Preferably, the Chinese medicine extract is prepared from Polygonatum odoratum and Crataegus pinnatifida in a mass ratio of 1-2:1-2.

[0013] More preferably, the method for preparing the traditional Chinese medicine extract comprises:

[0014] Mix polygonatum odoratum and hawthorn according to the dosage, crush to 80-100 mesh, add water, decoct, filter, add water to the residue and continue to decoct, filter, combine the filtrate, concentrate, and obtain the Chinese medicine extract.

[0015] More preferably, the mass ratio of the crushed medicinal material to water is 1:6-7;

[0016] The decoction time is 2 to 3 hours;

[0017] The mass ratio of the filter residue to water is 1:6-7;

[0018] The concentration is carried out to a crude drug amount of 4 to 6 mg / mL.

[0019] The present invention provides a method for preparing the python oil eye cream having the effect of reducing eye lines and removing wrinkles, comprising the following steps:

[0020] (1) Mix the components according to the dosage of each component in the formula, stir evenly, and obtain the effective ingredients;

[0021] (2) adding water to the thickener, stirring, adding an emulsifier, continuing to stir, and heating to 60-65° C., homogenizing at 3000-3500 r / min for 2-3 min, and then waiting for the temperature to drop to 25-30° C., adding the effective ingredients obtained in step (1), stirring, and obtaining a python oil eye cream with eye wrinkle and line lightening effects.

[0022] The present invention also provides the use of the python oil eye cream with eye wrinkle and wrinkle fading effect in fading crow's feet around the eyes.

[0023] The present invention also provides application of the python oil eye cream with eye wrinkle and lightening effects in improving the elasticity coefficient of skin around the eyes.

[0024] Python oil, processed from the fat of pythons, has a long history of medicinal use. It was first recorded in the "Five-two Prescriptions for Diseases" in the Western Han Dynasty. Python oil is rich in unsaturated fatty acids such as α-linolenic acid, oleic acid, linoleic acid, DHA, etc., and has excellent compatibility and complementarity with the physiological growth characteristics of human skin. Python oil has anti-inflammatory, anti-allergic, and antipruritic effects, and has a significant effect on maintaining the moisture of skin tissue, which can effectively fight and delay skin aging.

[0025] Hydrolyzed β-glucan (HYDROLYZED BETA-GLUCAN), β-glucan has good moisturizing and repairing properties, can increase the moisture content of the skin, improve the problem of dry and rough skin. At the same time, it can also promote the repair and regeneration of skin cells, reduce the appearance of wrinkles and fine lines. β-glucan has antioxidant and anti-inflammatory properties, can protect the skin from free radical damage, reduce the occurrence of skin inflammation, make the skin healthier and younger, suitable for dry and aging skin.

[0026] Polygonatum odoratum contains odoratan and four types of polygonatum-fructan-OA, B, C, D, as well as chemical components such as azetidin-2-carboxylic acid, which can increase the adhesion between skin cells, making the skin tighter and thus reducing water loss. In addition, Polygonatum odoratum extract can significantly increase the activity of superoxide dismutase in the skin, reduce the level of malondialdehyde, protect collagen and elastic fibers from damage, keep the skin firm and elastic, and reduce wrinkles and fine lines.

[0027] Hawthorn (CRATAEGI FRUCTUS), rich in flavonoids and vitamin C, can effectively remove free radicals in the body, reduce the damage of free radicals to skin cells, delay the cell aging process, make the skin firmer and smoother, and reduce the production of wrinkles and fine lines.

[0028] Rosa canina fruit oil is rich in unsaturated fatty acids, linoleic acid and vitamin A. It can prevent moisture loss from the epidermis, soften the skin, help regenerate the stratum corneum, and has the effects of soothing the skin, anti-oxidation, preventing wrinkles, and whitening and removing spots.

[0029] PINUS SYLVESTRIS CONE EXTRACT is extracted from the cones of European pine. It can maintain stable hydration and enhance the skin's ability to retain water. It activates skin microcirculation, increases the skin's nutrient supply, promotes the synthesis of elastic fibers and collagen, enhances skin's elasticity and firmness, reduces the appearance of wrinkles and fine lines, and reduces the damage of free radicals to skin cells. At the same time, its fragrance can be used to cover up the bad smell in the product, giving people a fresh and soothing experience.

[0030] Compared with the prior art, the present invention has the following beneficial effects:

[0031] The invention selects python oil, Chinese medicine extract (polygonatum and hawthorn), hydrolyzed β-glucan, dog rose fruit oil, hydrolyzed olive leaf extract, sophora flavescens root extract, European red pine cone extract, Laminaria japonica extract and Myrrha leaf cell extract, scientifically proportions, synergistically enhances the effect, can effectively inhibit the activity of elastase, achieve the effect of fading crow's feet and fine lines around the eyes, achieve good anti-wrinkle and anti-aging effects, and effectively solve the skin aging problem caused by internal and external factors. DETAILED DESCRIPTION

[0032] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0033] Unless otherwise specified, the experimental methods used in the embodiments of the present invention are all conventional methods.

[0034] Unless otherwise specified, the materials, reagents, etc. used in the embodiments of the present invention can be obtained from commercial sources.

[0035] The python oil used in the embodiments and comparative examples of the present invention can be commercially available python oil.

[0036] Example 1

[0037] Python oil eye cream with eye wrinkle and wrinkle-removing effects, wherein the proportion of raw materials (by weight) of the effective ingredients is as follows:

[0038]

[0039] The Chinese medicine extract in the formula is prepared from Polygonatum odoratum and Crataegus pinnatifida, and the specific steps are as follows:

[0040] (1) Mix Polygonatum odoratum and Crataegus pinnatifida in a mass ratio of 1:1, crush to 80-100 mesh, add 6 times the weight of the medicinal materials in water and boil for 2 h, filter, add an equal amount of water to the residue and continue boiling for 2 h, filter, and combine the two filtrates to obtain a Chinese medicine decoction;

[0041] (2) The decoction is concentrated by a rotary evaporator to obtain a crude drug content of 4 to 6 mg / mL, thereby obtaining a Chinese medicine extract.

[0042] Example 2

[0043] Python oil eye cream with eye wrinkle and wrinkle-removing effects, wherein the proportion of raw materials (by weight) of the effective ingredients is as follows:

[0044]

[0045]

[0046] The Chinese medicine extract in the formula is prepared from Polygonatum odoratum and Crataegus pinnatifida, and the specific steps are as follows:

[0047] (1) Mix Polygonatum odoratum and Crataegus pinnatifida in a mass ratio of 1:1, crush to 80-100 mesh, add 6 times the weight of the medicinal materials in water and boil for 2 h, filter, add an equal amount of water to the residue and continue boiling for 2 h, filter, and combine the two filtrates to obtain a Chinese medicine decoction;

[0048] (2) The decoction is concentrated by a rotary evaporator to obtain a crude drug content of 4 to 6 mg / mL, thereby obtaining a Chinese medicine extract.

[0049] Example 3

[0050] Python oil eye cream with eye wrinkle and wrinkle-removing effects, wherein the proportion of raw materials (by weight) of the effective ingredients is as follows:

[0051]

[0052] The Chinese medicine extract in the formula is prepared from Polygonatum odoratum and Crataegus pinnatifida, and the specific steps are as follows:

[0053] (1) Mix Polygonatum odoratum and Crataegus pinnatifida in a mass ratio of 1:1, crush to 80-100 mesh, add 6 times the weight of the medicinal materials in water and boil for 2 h, filter, add an equal amount of water to the residue and continue boiling for 2 h, filter, and combine the two filtrates to obtain a Chinese medicine decoction;

[0054] (2) The decoction is concentrated by a rotary evaporator to obtain a crude drug content of 4 to 6 mg / mL, thereby obtaining a Chinese medicine extract.

[0055] Comparative Example 1

[0056] The difference between this comparative example and Example 1 is that python oil is replaced by coconut oil.

[0057] Python oil eye cream with eye wrinkle and wrinkle-removing effects, wherein the proportion of raw materials (by weight) of the effective ingredients is as follows:

[0058]

[0059] The Chinese medicine extract in the formula is prepared from Polygonatum odoratum and Crataegus pinnatifida, and the specific steps are as follows:

[0060] (1) Mix Polygonatum odoratum and Crataegus pinnatifida in a mass ratio of 1:1, crush to 80-100 mesh, add 6 times the weight of the medicinal materials in water and boil for 2 h, filter, add an equal amount of water to the residue and continue boiling for 2 h, filter, and combine the two filtrates to obtain a Chinese medicine decoction;

[0061] (2) The decoction is concentrated by a rotary evaporator to obtain a crude drug content of 4 to 6 mg / mL, thereby obtaining a Chinese medicine extract.

[0062] Comparative Example 2

[0063] The difference between this comparative example and Example 1 is that the Chinese medicine extract is discarded, and the missing amount is allocated to the hydrolyzed olive leaf extract and the Sophora flavescens root extract accordingly.

[0064] Python oil eye cream with eye wrinkle and wrinkle-removing effects, wherein the proportion of raw materials (by weight) of the effective ingredients is as follows:

[0065]

[0066] Comparative Example 3

[0067] The difference between this comparative example and Example 1 is that the Laminaria japonica extract and the Commiphora myrrha leaf cell extract are replaced by α-bisabolol.

[0068] Python oil eye cream with eye wrinkle and wrinkle-removing effects, wherein the proportion of raw materials (by weight) of the effective ingredients is as follows:

[0069]

[0070]

[0071] The Chinese medicine extract in the formula is prepared from Polygonatum odoratum and Crataegus pinnatifida, and the specific steps are as follows:

[0072] (1) Mix Polygonatum odoratum and Crataegus pinnatifida in a mass ratio of 1:1, crush to 80-100 mesh, add 6 times the weight of the medicinal materials in water and boil for 2 h, filter, add an equal amount of water to the residue and continue boiling for 2 h, filter, and combine the two filtrates to obtain a Chinese medicine decoction;

[0073] (2) The decoction is concentrated by a rotary evaporator to obtain a crude drug content of 4 to 6 mg / mL, thereby obtaining a Chinese medicine extract.

[0074] Comparative Example 4

[0075] The difference between this comparative example and Example 1 is that the amount of Rosa canina fruit oil is reduced, and the missing amount is allocated to other raw materials accordingly.

[0076] Python oil eye cream with eye wrinkle and wrinkle-removing effects, wherein the proportion of raw materials (by weight) of the effective ingredients is as follows:

[0077]

[0078] The Chinese medicine extract in the formula is prepared from Polygonatum odoratum and Crataegus pinnatifida, and the specific steps are as follows:

[0079] (1) Mix Polygonatum odoratum and Crataegus pinnatifida in a mass ratio of 1:1, crush to 80-100 mesh, add 6 times the weight of the medicinal materials in water and boil for 2 h, filter, add an equal amount of water to the residue and continue boiling for 2 h, filter, and combine the two filtrates to obtain a Chinese medicine decoction;

[0080] (2) The decoction is concentrated by a rotary evaporator to obtain a crude drug content of 4 to 6 mg / mL, thereby obtaining a Chinese medicine extract.

[0081] Application Example 1

[0082] The preparation method of the python oil eye cream having the effect of reducing eye lines and removing wrinkles comprises the following specific steps:

[0083] (1) According to the dosage of the raw materials in the above embodiment, the raw materials are mixed and stirred evenly to obtain the effective ingredients of the python oil eye cream with the effect of lightening eye lines and removing wrinkles;

[0084] (2) The dosage of python oil eye cream: 20 parts of active ingredient, 2.5 parts of emulsifier, 3.5 parts of thickener, and deionized water to 100 parts;

[0085] (3) Add deionized water to the thickener, stir thoroughly, add an emulsifier, continue stirring, and heat to 60-65° C., homogenize at 3000-3500 r / min for 2-3 min, wait until the temperature drops to 25-30° C., add the effective ingredients obtained in step (1), stir thoroughly, and obtain a python oil eye cream with eye wrinkle and wrinkle removal effects.

[0086] Application Example 2

[0087] The in vitro anti-wrinkle efficacy was evaluated using an elastase inhibition model as follows:

[0088] According to EnzChek TM Elastase detection kit, using the buffer in the kit to dilute the effective ingredients of Examples 1 to 3 and Comparative Examples 1 to 4 respectively, prepare sample solution, add 50 μL sample solution to a 96-well plate, then add 100 μL, 0.2U / mL elastase working solution, after oscillating reaction at room temperature for 15 minutes, add 50 μL, 100 μg / mL elastase fluorescent coupling to each well, incubate in dark at room temperature for 30 minutes to obtain a sample group; replace the sample solution with an equal amount of 50 μL buffer, and use the same reaction steps as above to obtain a control group; replace the sample solution with an equal amount of 50 μL buffer, replace the elastase working solution with an equal amount of 100 μL buffer, and use the same reaction steps as above to obtain a solvent group. Use a fluorescent microplate reader at an excitation wavelength of 485 nm and an emission wavelength of 530 nm to measure the fluorescence intensity of the sample group, control group and solvent group, and calculate the inhibitory ability of the sample on elastase.

[0089] Elastase inhibition rate / % = [1-(MFI 样品组 -MFI 溶剂组 ) / (MFI 对照组 -MFI 溶剂组 ]×100%.

[0090] Table 1 Inhibition ability of different samples on elastase activity

[0091]

[0092]

[0093] An in vitro elastase inhibition model was used to evaluate the effect of the samples on skin elastase activity. Fluorescently labeled DQ elastin conjugate was used as a substrate to measure the activity of the protease to evaluate the anti-wrinkle and firming effects of the samples.

[0094] It can be seen from the test results in Table 1 that as the concentration increases, the sample's ability to inhibit elastase increases accordingly. Compared with the comparative example, under the same concentration conditions, the functional ingredient composition of the embodiment of the present invention has better elastase inhibition ability, and the sample has good anti-wrinkle effect.

[0095] Application Example 3

[0096] The anti-wrinkle effect of the eye area was evaluated by using a human anti-wrinkle test with its own parallel control. The specific method is as follows:

[0097] 1. Materials and Instruments

[0098] (I) Test product: python oil eye cream prepared using the functional ingredients of Example 1

[0099] (II) Testing instruments:

[0100] 1.VISIA-CR facial image analysis system.

[0101] 2. Cormeometer CM825 skin moisture meter.

[0102] 3. Cutometer MPA580 skin elasticity measuring instrument.

[0103] 2. Test methods

[0104] (I) Test environment conditions

[0105] Test environment temperature: 20℃~22℃, humidity: 40%~60%, real-time dynamic monitoring.

[0106] (II) Subject screening

[0107] 1. Number of subjects: 30.

[0108] 2. Subject conditions:

[0109] (1) Inclusion criteria:

[0110] ① Women aged 30 to 35, with mild or severe fine lines around the eyes.

[0111] ② The patient is in good general health and has no major systemic diseases.

[0112] ③ Be able to strictly follow the requirements and time schedule of the research plan and sign the informed consent form and confidentiality agreement.

[0113] (2) Exclusion criteria:

[0114] People with sensitive constitution, skin diseases, those who have used hormone drugs and immunosuppressants within one month, or those who have undergone chemical peeling (acid treatment), microdermabrasion, laser dermabrasion and other cosmetic treatments on the face within three months, as well as other situations where they are not suitable for testing.

[0115] (III) Product Usage

[0116] Divide the skin around the eyes on both sides into a test area and a control area. After cleansing, apply an appropriate amount of the product evenly to the skin around the eyes in the test area. Use your fingertips to massage along the skin around the eyes and press gently to promote product absorption. Do not do anything to the control area. Use once in the morning and evening every day for 28 consecutive days.

[0117] During the trial, subjects are prohibited from using preparations for anti-wrinkle, repair, or increasing skin oil content: subjects are prohibited from intravenous, injection, oral or other forms of ingestion of preparations that may affect anti-wrinkle and repair tests: subjects should mainly engage in indoor activities and avoid long-term exposure to outdoor light.

[0118] (IV) Objective and quantitative evaluation

[0119] 30 minutes after facial cleansing, the face was photographed using VISIA-CR facial image analyzer, the crow's feet area was analyzed, and the skin moisture content and skin elasticity (R2) were tested using CM825 and MPA580. Then the product was distributed and the usage instructions were given. The subjects were required to return for a visit 28 days (D28) after using the product and undergo the same index test.

[0120] The test of the same subject should be completed by the same instrument and the same tester. The test site should be kept consistent between the two test time points.

[0121] 3. Test results

[0122] (I) Analysis of skin moisture content

[0123] Table 2 Changes in skin moisture content before and after use

[0124] Test site D0 D28 Test area 70.24±6.32 <![CDATA[76.56±6.18 * ]]> Control area 71.30±6.24 69.77±7.32

[0125] Note: Significant differences are marked with *p<0.05, **p<0.01

[0126] From the test results in Table 2, it can be seen that the skin moisture content increased after 28 days of using the product compared with that before using the product, and there was a statistical difference compared with D0 (p<0.05).

[0127] (II) Skin elasticity analysis

[0128] Table 3 Changes in skin elasticity coefficient R2 before and after use

[0129] Test site D0 D28 Test area 0.57±0.07 <![CDATA[0.72±0.09 ** ]]> Control area 0.56±0.07 <![CDATA[0.60±0.07 * ]]>

[0130] Note: Significant differences are marked with *p<0.05, **p<0.01

[0131] From the test results in Table 3, it can be seen that the skin elasticity was improved after 28 days of using the product compared with that before using the product, and there was a statistical difference compared with D0 (p<0.01).

[0132] (III) Analysis of crow’s feet area

[0133] Table 4 Changes in crow's feet area before and after use

[0134] Test site D0 D28 Test area 2.12±2.04 <![CDATA[1.88±1.73 * ]]> Control area 2.34±2.15 2.36±2.28

[0135] Note: Significant differences are marked with *p<0.05, **p<0.01

[0136] From the test results in Table 4, it can be seen that the area of ​​crow's feet wrinkles was improved after 28 days of using the product compared with that before using the product, and there was a statistical difference compared with D0 (p<0.05).

[0137] 4. Summary

[0138] 1. Analysis of skin moisture content

[0139] After using the test product, the moisture content of the subjects' skin around the eyes showed an upward trend at the follow-up time point D28, and the difference was significant compared with D0 (p<0.05), indicating that the moisture content of the skin around the eyes increased after using the product, and the product has a moisturizing effect.

[0140] 2. Skin elasticity analysis

[0141] After using the test product, the elasticity coefficient R2 of the subjects' periocular skin showed an upward trend at the follow-up time point D28, and the difference was significant compared with D0 (p<0.01), indicating that the elasticity of the periocular skin increased after using the product, and the product has the effect of improving skin radiance.

[0142] 3. Analysis of crow's feet area

[0143] After using the test product, the area of ​​crow's feet around the eyes of the subjects tended to shrink at the follow-up time point D28, and the difference was significant compared with D0 (p<0.05), indicating that the area of ​​crow's feet around the eyes became smaller after using the product, and the product has the effect of reducing crow's feet around the eyes and has anti-wrinkle effect.

[0144] The above is a preferred embodiment of the present invention. It should be pointed out that a person skilled in the art can make several improvements and modifications without departing from the principle of the present invention. These improvements and modifications are also considered to be within the scope of protection of the present invention.

Claims

1. A python oil eye cream with the effect of lightening eye lines and removing wrinkles, characterized in that: The composition comprises the following components by weight: 10-20 parts of python oil, 2-5 parts of Chinese medicine extract, 2-5 parts of hydrolyzed β-glucan, 10-15 parts of dog rose fruit oil, 1-3 parts of hydrolyzed olive leaf extract, 1-3 parts of sophora flavescens root extract, 5-15 parts of European red pine cone extract, 0.3-0.6 parts of Laminaria japonica extract and 0.3-0.6 parts of myrrh leaf cell extract; The traditional Chinese medicine extract is prepared from polygonatum odoratum and hawthorn.

2. The python oil eye cream with eye wrinkle and lightening effect according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 10-15 parts of python oil, 2-4 parts of Chinese medicine extract, 2-3 parts of hydrolyzed β-glucan, 10-15 parts of dog rose fruit oil, 1-2 parts of hydrolyzed olive leaf extract, 1-3 parts of sophora flavescens root extract, 8-15 parts of European red pine cone extract, 0.4-0.6 parts of Laminaria japonica extract and 0.4-0.6 parts of myrrh leaf cell extract.

3. The python oil eye cream with eye wrinkle and lightening effect according to claim 2, characterized in that: The composition comprises the following components by weight: 10 parts of python oil, 2 parts of Chinese medicine extract, 2 parts of hydrolyzed β-glucan, 15 parts of dog rose fruit oil, 2 parts of hydrolyzed olive leaf extract, 3 parts of sophora flavescens root extract, 10 parts of European red pine cone extract, 0.5 parts of Laminaria japonica extract and 0.5 parts of myrrh leaf cell extract; Or, in parts by weight, comprising the following components: 10 parts of python oil, 4 parts of Chinese medicine extract, 2 parts of hydrolyzed β-glucan, 10 parts of dog rose fruit oil, 1 part of hydrolyzed olive leaf extract, 1 part of Sophora flavescens root extract, 15 parts of European red pine cone extract, 0.5 parts of Laminaria japonica extract and 0.5 parts of Commiphora myrrha leaf cell extract; Or, in parts by weight, it includes the following components: 15 parts of python oil, 2 parts of traditional Chinese medicine extract, 2 parts of hydrolyzed β-glucan, 10 parts of dog rose fruit oil, 2 parts of hydrolyzed olive leaf extract, 3 parts of Sophora flavescens root extract, 8 parts of European red pine cone extract, 0.5 parts of Laminaria japonica extract and 0.5 parts of Myrrha leaf cell extract.

4. The python oil eye cream with eye wrinkle and lightening effect according to any one of claims 1 to 3, characterized in that: The traditional Chinese medicine extract is prepared from polygonatum odoratum and hawthorn in a mass ratio of 1-2:1-2.

5. The python oil eye cream with eye wrinkle and lightening effect according to claim 4, characterized in that: The preparation method of the Chinese medicine extract comprises: Mix polygonatum odoratum and hawthorn according to the dosage, crush to 80-100 mesh, add water, decoct, filter, add water to the residue and continue to decoct, filter, combine the filtrate, concentrate, and obtain the Chinese medicine extract.

6. The python oil eye cream with eye wrinkle and lightening effect according to claim 5, characterized in that: The mass ratio of ground medicinal materials to water is 1:6-7; The decoction time is 2 to 3 hours; The mass ratio of the filter residue to water is 1:6-7; The concentration is carried out to a crude drug amount of 4 to 6 mg / mL.

7. The method for preparing the python oil eye cream with eye wrinkle and lightening effect as claimed in any one of claims 1 to 6, characterized in that: The steps include: (1) Mix the components according to the dosage of each component in the formula, stir evenly, and obtain the effective ingredients; (2) adding water to the thickener, stirring, adding an emulsifier, continuing to stir, and heating to 60-65° C., homogenizing at 3000-3500 r / min for 2-3 min, and then waiting for the temperature to drop to 25-30° C., adding the effective ingredients obtained in step (1), stirring, and obtaining a python oil eye cream with eye wrinkle and line lightening effects.

8. Use of the python oil eye cream with eye wrinkle and lightening effect as claimed in any one of claims 1 to 6 in lightening crow's feet around the eyes.

9. Use of the python oil eye cream with eye wrinkle and lightening effect as claimed in any one of claims 1 to 6 in improving the elasticity coefficient of the skin around the eyes.