Liquid nitrogen container provided with loading rod rapid cap mounting mechanical device
By designing the load rod ladder conveying mechanism and rod cap sleeve in the liquid nitrogen container, the fast positioning and socket of the load rod and rod cap are achieved, solving the instability and safety of the sleeve rod operation in the liquid nitrogen environment, and improving the operation efficiency and safety.
Patent Information
- Application Number
- CN202510497440.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-21
- Publication Date
- 2025-05-23
- Estimated Expiration
- 2045-04-21
AI Technical Summary
The rod operation of embryo/egg freezing in liquid nitrogen environment is easily affected by liquid nitrogen mist, liquid nitrogen liquid surface fluctuations and vision differences, resulting in repeated operations increasing the risk of embryo/egg loss, and in a liquid nitrogen environment for a long time increases the risk of finger frostbite and inhalation of nitrogen.
A liquid nitrogen container equipped with a fast-loading mechanism for loading rods is designed. The positioning and fast-fitting of the loading rods and rod caps is achieved through the loading rods and rod caps, reducing the number of times the operator manually puts the caps.
Improves the success rate of tightening of the load rod and rod cap, reduces the risk of embryo/egg loss, and reduces the safety risks of operators in liquid nitrogen environments.
Smart Images

Figure CN120021614A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of a robot or a container equipped with a manipulation device, and in particular to a liquid nitrogen container equipped with a carrier rod rapid capping mechanical device. Background Art
[0002] There are two methods for freezing embryos / eggs: programmed freezing and vitrification. The main technical route of vitrification is to balance the embryos / eggs with high concentrations of cryoprotectants for a certain period of time, reduce the cell volume by dehydration, and then place them on a freezing rod and directly put them into liquid nitrogen to make the cells instantly vitrified, so as to reduce damage caused by ice formation in the cells. The last and most important step of vitrification technology is to seal the freezing rod containing the embryos / eggs under liquid nitrogen.
[0003] However, during the above-mentioned sleeve rod operation, there are the following problems: when the operating technician performs the capping and sealing operation on the thin and transparent slide under liquid nitrogen, it is easy to be affected by factors such as liquid nitrogen mist, liquid nitrogen level fluctuations and individual vision differences, resulting in repeated capping operations. And each additional capping operation increases the risk of embryo / egg loss; at the same time, being in a liquid nitrogen environment for a long time will increase the risk of frostbite on the operating technician's fingers and inhalation of excessive nitrogen, which will affect the health of the operator.
[0004] To this end, Chinese utility model patent CN2023203962084 discloses a novel automatic rod sleeve device for embryo freezing carrier rods, which realizes automatic rod sleeve by gravity. However, because the frozen embryos / eggs minimize the carrying of excess liquid, the reduction in volume can quickly reduce the freezing temperature and cross the dangerous period of ice crystal formation, so the width of the transparent slide end is only about 1 mm. It is obviously impossible to achieve a tight fit between the carrier rod and the rod cap by relying solely on the weight of the carrier rod itself to achieve the rod sleeve operation. Summary of the invention
[0005] The present invention provides a liquid nitrogen container equipped with a rapid capping mechanical device for carrier rods, which has the advantages of assisting operators in positioning carrier rods and rod caps and being able to quickly process batch sample carrier rods.
[0006] The objective of the present invention is achieved through the following technical solutions: The liquid nitrogen container equipped with a rod fast capping mechanical device comprises a rod carrying step-by-step conveying mechanism and a rod cap sleeve; the rod carrying step-by-step conveying mechanism comprises a transmission rail, a push rod, a crank lever and a transmission disc; the transmission rail is provided with an out-of-position sliding groove adapted to the sliding of the rod, one end of the push rod is in transmission connection with the transmission disc, and the other end is in transmission with the rod for advancement; the transmission disc is provided with a cam sliding groove, one end of the crank lever is slidably arranged in the cam sliding groove, and the other end is in transmission connection with the rod on the out-of-position sliding groove, and the crank lever is rotatably installed on the transmission rail; the rod cap sleeve is located below the rod.
[0007] Among them, the advantage of the rod-carrying ladder conveying mechanism is that the rod-carrying rods can be arranged from top to bottom and pushed to the top of the rod cap sleeve in sequence. After the operator pushes the rod-carrying rod downward with tweezers to fit the rod cap, the rod-carrying rod with the cap sleeve is pushed out of the exit chute, and the rod-carrying rod is fixed in the rod cap sleeve, thus completing the rod sleeve operation.
[0008] Preferably, the load-carrying rod step-by-step conveying mechanism further comprises a transmission convex portion, and the end of the propulsion rod facing away from the load-carrying rod is provided with a through groove adapted to the movement path of the transmission convex portion.
[0009] Preferably, the rod carrier ladder conveying mechanism further comprises a transmission wheel, a connecting rod and a rotating handle; the transmission wheel is meshed and transmission-connected with the transmission disc, one end of the connecting rod is fixed to the transmission wheel, and the other end is fixed to the rotating handle.
[0010] Preferably, the rod-carrying ladder conveying mechanism also includes a cap-mounting assembly, which includes a slide plate, an elastic spring and a slider. The slide plate is fixed to the transmission rail and is located at the end of the exit slide groove. The slider is slidably arranged on the slide plate, and the rod-carrying clamp is arranged between the two slide plates. One end of the elastic spring is fixed to the bottom end of the slide plate, and the other end is fixed to the slider.
[0011] Among them, the advantage of the cap-mounting assembly is that it completes the positioning between the carrier rod and the rod cap, and can adapt to the operator to complete the process of pressing down the carrier rod to realize the process of putting the cap on the carrier rod.
[0012] Preferably, an entry chute is provided on the transmission rail, the entry chute and the exit chute are connected, and the push rod is located at the connection between the entry chute and the exit chute.
[0013] Preferably, a guide tube for guiding the insertion of the carrier rod is installed correspondingly at the upper end of the feed chute.
[0014] Preferably, the liquid nitrogen container further comprises a containing shell, an outer shell and a fixing frame; The accommodating shell and the outer shell are rotatably sleeved; the fixing frame includes a connecting rod, a connecting plate, a fixing ring and a supporting rod; the rod cap sleeves are circumferentially arranged and fixed on the fixing ring, one end of the connecting rod is fixed to the fixing ring, and the other end is fixed to the connecting plate, the connecting plate and the bottom of the accommodating shell are fixed by an axis, one end of the supporting rod is fixed to the connecting plate, and the other end is rotatably connected to the transmission rail.
[0015] Preferably, a feed port and an observation port are provided at the upper end of the outer shell, and both the feed port and the observation port are provided with sealing covers, and the observation port is located above the slide rail plate.
[0016] Preferably, an indicating extension portion is provided at the bottom side end of the accommodating shell, and an indicating scale is provided on the indicating extension portion, and the orientation of the indicating scale is consistent with that of the rod cap sleeve.
[0017] Preferably, a rod indicator protrusion is provided on the side wall of the outer shell.
[0018] Compared with the prior art, the advantages or beneficial effects of the technical solution of the present application include: 1. Push the carrying rod along the exiting slot in sequence until it reaches the top of the rod cap sleeve at the end, so that the carrying rod and the rod cap placed on the rod cap sleeve are aligned in the vertical position. When the operator drives the carrying rod downward toward the rod cap, the carrying rod and the rod cap can be sleeved and pressed together, so that the two can be tightly fixed.
[0019] 2. Since the position of the carrier rod is pre-arranged, after driving it to the top of the rod cap, the success rate of one-time tightening is high, avoiding the loss of eggs during the rod installation and sealing operation. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 It is a schematic diagram of the structure of a liquid nitrogen container equipped with a rapid capping mechanism for a carrier rod; Figure 2 It is a schematic diagram of the cross-sectional structure of a liquid nitrogen container; Figure 3 It is a three-dimensional structural schematic diagram of the rod-carrying ladder transmission mechanism; Figure 4 for Figure 3 A magnified view of part A in FIG. Figure 5 for Figure 3 A magnified view of part B in FIG. Figure 6 It is a top view of the rod-carrying ladder conveying mechanism; Figure 7 The motion state diagram of the carrier rod ladder transmission mechanism (the crank lever and the carrier rod are not in contact, and the push rod pushes the carrier rod forward); Figure 8The motion state diagram of the rod-carrying ladder conveying mechanism (the crank lever contacts the rod-carrying rod, the push rod retracts, and the next rod-carrying rod falls in); Fig. 9 Schematic diagram for implementing the pairing operation of the three carrier rods and rod caps (with transparent acrylic installed); Fig.10 Schematic diagram of the pairing operation of the carrier rod and the rod cap in Example 4.
[0021] In the figure: 1, rotating handle, 2, connecting rod, 3, transmission wheel, 4, rod cap sleeve, 6, guide tube, 7, connecting plate, 8, connecting rod, 9, transmission plate, 10, pushing rod, 11, transmission convex part, 12, cam slide groove, 13, support rod, 14, transmission rail, 15, crank lever, 16, carrier rod, 17, slider, 18, elastic spring, 19, slide rail plate, 20, fixing ring, 23, shaft, 24, indicating extension part, 25, indicating scale, 26, carrier rod indicating convex part, 30, outer shell, 31, receiving shell, 32, rotating lever, 33, push rod, DETAILED DESCRIPTION
[0022] The following will describe the implementation methods of the present application in detail with reference to the accompanying drawings and embodiments, so that the implementation process of how the present application applies technical means to solve technical problems and achieve corresponding technical effects can be fully understood and implemented accordingly. The embodiments of the present application and the various features in the embodiments can be combined with each other without conflict, and the technical solutions formed are all within the protection scope of the present application.
[0023] It should be clear that the embodiments described below are only part of the embodiments of the present application, rather than all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by technicians in the relevant field without making creative work are within the scope of protection of the present application.
[0024] Example 1: Figure 1-Figure 6As shown, a liquid nitrogen container equipped with a fast capping mechanism for carrying rods includes a step-by-step conveying mechanism for carrying rods and a rod cap sleeve 4; the step-by-step conveying mechanism for carrying rods includes a transmission rail 14, a push rod 10, a crank lever 15, a transmission disc 9, a transmission convex portion 11, a transmission wheel 3, a connecting rod 2 and a rotating handle 1; the transmission rail 14 is provided with an out-of-position chute adapted to the sliding of the carrying rod 16, one end of the push rod 10 is connected to the transmission disc 9 for transmission, and the other end is connected to the carrying rod 16 for transmission; the transmission disc 9 is provided with a cam chute 12, one end of the crank lever 15 is slidably arranged in the cam chute 12, and the other end is connected to the carrying rod 16 on the out-of-position chute for transmission, and the crank lever 15 is rotatably installed on the transmission rail 14; the rod cap sleeve 4 is located below the carrying rod 16. The end of the push rod 10 facing away from the carrying rod 16 is provided with a through groove adapted to the motion path of the transmission convex portion 11. The transmission wheel 3 is meshed and connected to the transmission disc 9 for transmission, one end of the connecting rod 2 is fixed to the transmission wheel 3, and the other end is fixed to the rotating handle 1.
[0025] The transmission rail 14 is provided with an infeed chute, the infeed chute and the outfeed chute are connected, and the push rod 10 is located at the connection between the infeed chute and the outfeed chute. The upper end of the infeed chute is correspondingly provided with a guide tube 6 for guiding the loading rod 16 to be placed.
[0026] The connection relationship and working principle between the internal components of the rod carrier ladder transmission mechanism are as follows: When the carrying rods 16 enter the feed chute along the guide tube 6, the number of carrying rods that can be loaded into each liquid nitrogen tank is fixed. Figure 3 As shown, 30 carrier rods can be loaded, and the corresponding rod caps are 30. When the operator inserts the carrier rods along the opening of the liquid nitrogen tank, the rotating handle 1 is rotated to drive the transmission disc 9 to rotate through the transmission wheel 3.
[0027] Since the cam slot 12 is composed of a large arc and a small arc. When the end of the crank lever 15 moves to the large arc, the other end of the crank lever 15 does not contact the carrier rod 16. On the contrary, when the end of the crank lever 15 moves to the small arc, the other end of the crank lever 15 contacts the carrier rod 16, so that the carrier rod 16 on the in-position slot falls into the out-position slot (i.e., above the end of the propulsion rod 10). In the above process, when the transmission protrusion 11 moves to the left ( Figure 4 ), which will drive the end of the propulsion rod 10 forward, thereby pushing the carrier rod 16 forward. Conversely, when it moves to the right side ( Figure 4 ), the push rod 10 will return to its original position. Figure 7-Figure 8 Status display.
[0028] In the above process, the sliding power of the carrying rod 16 on the in-position chute is mainly its own gravity. For this reason, the portion of the transmission rail 14 corresponding to the in-position chute can be designed as an inclined surface, so as to facilitate the carrying rod to overcome its own gravity and the buoyancy of liquid nitrogen, so that it can actively fall into the out-position chute. In addition, although the carrying rod 16 can rely on the push of the previous carrying rod 16 on the out-position chute, in order to avoid insufficient power, the portion of the transmission rail 14 corresponding to the out-position chute can be designed as an inclined surface, so that the carrying rod 16 can slide along the out-position chute according to its own gravity until it slides between the two sliders 17.
[0029] Embodiment 2: Based on Embodiment 1, this embodiment further refines the structure of the rod-carrying ladder conveying mechanism as follows: like Figure 3 and Figure 5 As shown, the rod-carrying ladder conveying mechanism also includes a cap-mounting assembly, which includes a slide plate 19, an elastic spring 18 and a slider 17. The slide plate 19 is fixed to the transmission rail 14 and is located at the end of the exit slide groove. The slider 17 is slidably set on the slide plate 19, and the rod-carrying rod 16 is clamped between the two slide plates 19. One end of the elastic spring 18 is fixed to the bottom end of the slide plate 19, and the other end is fixed to the slider 17.
[0030] The component composition and working principle of the cap assembly are as follows: When the carrying rod 16 is pushed between the two slide rails 19, the operator can use tweezers to push the carrying rod toward the rod cap to make the two fit tightly. When the carrying rod 16 and the rod cap are fitted tightly, the operator can continue to push forward to push the carrying rod 16 out from between the two slide rails 19 (the bottom end of the rod cap is still in the rod cap sleeve 4, so after the carrying rod 16 is fitted tightly, it can be placed on the rod cap sleeve 4). After being pushed out, the slider 17 can be restored to its original position by the action of the elastic spring 18, and continue to wait for the next carrying rod 16 to perform the rod fitting operation.
[0031] During the above process, the operator can observe through the observation port whether the carrying rod 16 is pushed between the two slide rail plates 19 to assist in positioning.
[0032] This embodiment also includes a accommodating shell 31, an outer shell 30 and a fixing frame; the accommodating shell 31 and the outer shell 30 are rotatably sleeved; the fixing frame includes a connecting rod 8, a connecting disk 7, a fixing ring 20 and a support rod 13; the rod cap sleeve 4 is arranged in a circle and fixed on the fixing ring 20, one end of the connecting rod 8 is fixed to the fixing ring 20, and the other end is fixed to the connecting disk 7, the connecting disk 7 and the bottom of the accommodating shell 31 are fixed by the shaft 31, one end of the support rod 13 is fixed to the connecting disk 7, and the other end is rotatably connected to the transmission rail 14.
[0033] In this embodiment, a feed port and an observation port are provided at the upper end of the outer shell 30 , and both the feed port and the observation port are provided with sealing covers, and the observation port is located above the slide rail plate 19 .
[0034] In this embodiment, an indicating extension portion 24 is provided at the bottom side end of the accommodating shell 31 , and an indicating scale 25 is provided on the indicating extension portion 24 , and the orientation of the indicating scale 25 is consistent with that of the rod cap sleeve 4 .
[0035] In this embodiment, a rod indicator protrusion 26 is disposed on the side wall of the outer shell 30 .
[0036] When performing the positioning operation, the indicating extension part 24 can be rotated so that the indicating scale 25 corresponding to the rod cap sleeve 4 corresponds to the rod carrier indicating protrusion 26 on the outer shell 30, which means that the rod carrier 16 has been aligned with the next rod cap (the rod carrier 16 and the rod carrier indicating protrusion 26 are adjusted in advance).
[0037] Embodiment 3: This embodiment provides a method of providing a rod cap that is different from that of Embodiments 1-2: like Fig. 9 As shown, by setting a transparent acrylic at the observation port, the lower end of the transparent acrylic is located below the liquid nitrogen level and directly above the carrier rod 16. The operator observes the position of the carrier rod 16 below the liquid nitrogen through the transparent acrylic, which can avoid the interference of liquid nitrogen mist, and the practical effect is very good. At the same time, a gap can be left between the transparent acrylic and the carrier rod 16 to accommodate the operator inserting a metal rod and pushing the upper end of the carrier rod 16 to move downward, thereby completing the entire capping process.
[0038] Furthermore, in the present embodiment, in order to prevent the carrying rod 16 from falling into the liquid nitrogen when moving in the exit chute, the slider 17 can be rotatably connected to a limit plate (the limit plate can be reset by a torsion spring), so that the limit plate can limit the carrying rod 16 from accidentally moving and falling into the liquid nitrogen (the carrying rod 16 can be prevented from falling when sliding along the oblique exit chute).
[0039] Embodiment 4: Based on Embodiment 3, this embodiment again proposes a method of pushing the carrier rod 16 into the rod cap, which is different from the former, and is specifically: like Fig.10 As shown, the transparent acrylic is installed in the observation port and is aligned above the carrier rod 16 for observing the position of the carrier rod.
[0040] At the same time, an operation window is newly added, and a rotating lever 32 and a push rod 33 that can move in the vertical direction are rotatably installed inside the operation window. The rotating lever 32 and the push rod 33 are both L-shaped.
[0041] The operation process is as follows: S1, press the push rod 33 (located directly above the carrier rod 16) downward to make the carrier rod 16 move downward until it is fixed in the rod cap sleeve. S2, rotate the rotating lever 32 so that the end of the rotating lever 32 pushes the carrier rod 16 out of the two sliders 17 and places it in the rod cap sleeve 4.
[0042] In the above process, the process of rotating the lever 32 to bring out the carrier rod 16 can only be realized by taking into account the toughness of the carrier rod 16. After the operation is completed, the push rod 33 returns to its original position due to the elastic force of the spring.
[0043] In the above process, although the end of the push rod 33 is located above the carrier rod 16, it does not affect the operator's observation of the overall situation of the carrier rod 16 through the transparent acrylic (i.e., the situation where the end of the push rod 33 blocks the top of the carrier rod 16 is not considered).
Claims
1. A liquid nitrogen container equipped with a rapid capping device for a carrier rod, characterized in that: It includes a rod-carrying ladder transmission mechanism and a rod cap sleeve (4); The rod-carrying ladder-transfer mechanism comprises a transmission rail (14), a propulsion rod (10), a crank lever (15) and a transmission disc (9); The transmission rail (14) is provided with an out-of-position sliding groove adapted to slide the carrier rod (16); one end of the propulsion rod (10) is connected to the transmission plate (9) for transmission, and the other end is connected to the carrier rod (16) for propulsion transmission; the transmission plate (9) is provided with a cam sliding groove (12); one end of the crank lever (15) is slidably arranged in the cam sliding groove (12), and the other end is connected to the carrier rod (16) on the out-of-position sliding groove for transmission; the crank lever (15) is rotatably mounted on the transmission rail (14); the rod cap sleeve (4) is located below the carrier rod (16).
2. The liquid nitrogen container equipped with a rapid capping mechanism for a carrier rod according to claim 1, characterized in that: The rod carrier ladder transmission mechanism further comprises a transmission convex portion (11), and one end of the propulsion rod (10) facing away from the rod carrier (16) is provided with a through groove adapted to the movement path of the transmission convex portion (11).
3. The liquid nitrogen container equipped with a rapid capping mechanism for a carrier rod according to claim 1, characterized in that: The rod carrier ladder transmission mechanism further comprises a transmission wheel (3), a connecting rod (2) and a rotating handle (1); the transmission wheel (3) and the transmission plate (9) are meshed and transmission-connected, one end of the connecting rod (2) is fixed to the transmission wheel (3), and the other end is fixed to the rotating handle (1).
4. The liquid nitrogen container equipped with a rapid capping mechanism for a carrier rod according to claim 1, characterized in that: The rod carrying step-by-step conveying mechanism further comprises a capping assembly, the capping assembly comprising a slide rail plate (19), an elastic spring (18) and a slider (17); the slide rail plate (19) is fixed to the transmission rail (14) and is located at the end of the exit slide groove; the slider (17) is slidably arranged on the slide rail plate (19); the rod carrying (16) is clamped between the two slide rail plates (19); one end of the elastic spring (18) is fixed to the bottom end of the slide rail plate (19), and the other end is fixed to the slider (17).
5. The liquid nitrogen container equipped with a rapid capping mechanism for a carrier rod according to claim 1, characterized in that: The transmission rail (14) is provided with an infeed chute, the infeed chute and the outfeed chute are connected, and the push rod (10) is located at the connection between the infeed chute and the outfeed chute.
6. The liquid nitrogen container equipped with a rapid capping mechanism for a carrier rod according to claim 1, characterized in that: A guide tube (6) for guiding the carrier rod (16) to be placed is correspondingly installed at the upper end of the feed chute.
7. The liquid nitrogen container equipped with a rapid capping mechanism for a carrier rod according to claim 1, characterized in that: It also includes a receiving shell (31), an outer shell (30) and a fixing frame; The receiving shell (31) and the outer shell (30) are rotatably connected; The fixing frame comprises a connecting rod (8), a connecting plate (7), a fixing ring (20) and a supporting rod (13); The rod cap sleeves (4) are arranged in a circle and fixed on the fixing ring (20); one end of the connecting rod (8) is fixed to the fixing ring (20), and the other end is fixed to the connecting plate (7); the connecting plate (7) and the bottom of the accommodating shell (31) are fixed via a shaft (31); one end of the supporting rod (13) is fixed to the connecting plate (7), and the other end is rotatably connected to the transmission rail (14).
8. The liquid nitrogen container equipped with a rapid capping mechanism for a carrier rod according to claim 7, characterized in that: The outer shell (30) is provided with a feed port and an observation port at the upper end, and both the feed port and the observation port are provided with sealing covers, and the observation port is located above the slide rail plate (19).
9. The liquid nitrogen container equipped with a rapid capping mechanism for a carrier rod according to claim 7, characterized in that: An indication extension portion (24) is provided at the bottom side end of the accommodating shell (31), and an indication scale (25) is provided on the indication extension portion (24), and the orientation of the indication scale (25) is consistent with that of the rod cap sleeve (4).
10. The liquid nitrogen container equipped with a rapid capping mechanism for a carrier rod according to claim 7, characterized in that: A rod-carrying indicating protrusion (26) is provided on the side wall of the outer shell (30).
Citation Information
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Auxiliary safe docking device of human embryo freezing carrier poles under liquid nitrogen and using method of auxiliary safe docking device
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