Eye drops based on plant extracts and preparation device thereof
By using plant extracts such as North American witch hazel leaf water and rose extract in eye drops, combined with a special preparation device, the problem of eye drops being poor in eye metabolism and easy to sink to the bottom of the preparation device is solved, and better eye care effects and product quality are achieved.
Patent Information
- Application Number
- CN202510190972.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-20
- Publication Date
- 2025-05-27
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The existing eye drops have poor metabolism to the eye, no significant improvement in antioxidant capacity, and the eye drop preparation device is prone to bottom sinking, affecting product quality.
Design an eye drop based on plant extract, containing North American witch hazel leaf water, rose extract and other ingredients, combined with specific preparation devices, including auxiliary preparation cylinder, movable plug, stirring small leaves and stirring rod. Through the combination of the pneumatic cylinder and the piston rod, the solution can be fully mixed and avoided sinking.
This eye drop not only significantly relieves discomfort symptoms such as eye fatigue, dryness, and swelling, enhances eye barriers and antioxidant capabilities, improves eye health, and ensures consistency in product quality.
Smart Images

Figure CN120037290A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of eye drops, and in particular to an eye drop based on plant extracts and a preparation device thereof. Background Art
[0002] The eyes, known as the "windows of the soul", are one of the most important organs for humans to perceive external information. They can convey emotions, attitudes, and intentions, enhancing the connection between people. In addition, the health status of the eyes directly reflects an individual's overall health. Many diseases and conditions, such as diabetes, hypertension, glaucoma, and cataracts, may give early warnings through symptoms or changes in the eyes. Eye drops are eye care products designed for modern people who face electronic screens for a long time and overuse their eyes.
[0003] To relieve eye discomfort, eye drops are instilled into the eyes after long-term use of the eyes. Although existing eye drops can relieve symptoms such as dryness, fatigue, and discomfort in the eyes, their metabolism of the eyes is not good, and the antioxidant capacity of eye tissues is not significantly improved after use, resulting in patients being unable to effectively relieve symptoms such as eye fatigue and swelling discomfort. Moreover, a stirring preparation device is generally indispensable when making eye drops, but some extracts are prone to sink to the bottom during the preparation of eye drops, resulting in insufficient mixing of raw materials, which easily causes uneven quality of eye drops and affects product quality.
[0004] Therefore, in view of the problems that the above-mentioned eye drops have poor metabolism of the eyes, no obvious improvement in antioxidant capacity, and the problem that the preparation device of the problem eye drops is prone to sink to the bottom, affecting product quality, an eye drop based on plant extracts and a preparation device thereof can be designed. Summary of the Invention
[0005] In order to overcome the problems that eye drops have poor metabolism of the eyes, no obvious improvement in antioxidant capacity, and the problem that the preparation device of the problem eye drops is prone to sink to the bottom, affecting product quality.
[0006] The technical solution of the present invention is: an eye drop based on plant extracts, comprising the following components in parts by weight:
[0007] 75.00 - 85.00 parts of water of Hamamelis virginiana leaves,
[0008] 4.00 - 8.00 parts of 1,3 - propanediol,
[0009] 2.00 - 6.00 parts of Rosa rugosa flower extract,
[0010] 0.50 - 1.50 parts of nicotinamide,
[0011] 0.50 - 1.50 parts of β - glucan,
[0012] 0.50 - 1.50 parts of lutein,
[0013] 0.2 - 0.7 parts of sodium chloride,
[0014] 0.10 - 0.30 parts of sodium hyaluronate,
[0015] 0.10 - 0.30 parts of allantoin,
[0016] 0.10 - 0.30 parts of dipotassium glycyrrhizinate,
[0017] 0.10 - 0.20 parts of Artemisia argyi leaf extract,
[0018] 0.10 - 0.20 parts of Citrus paradisi fruit extract,
[0019] 0.10 - 0.20 parts of Cassia obtusifolia extract,
[0020] 2.50 - 7.00 parts of taurine.
[0021] Preferably, the preparation steps of Hamamelis virginiana leaf water are as follows: Put the washed Hamamelis virginiana leaves into a crusher for crushing to obtain crushed leaves with appropriate particle size. Then, add the crushed leaves and clear water to an extraction tank according to a solid - liquid ratio of 1:10 - 20, heat to 70 - 80 °C, and control the extraction time at 20 - 24 hours. After extraction, use a filter to separate the solid residue to obtain Hamamelis virginiana leaf water extract. Then, use the macroporous resin column purification method for purification, and then concentrate the purified extract to obtain concentrated Hamamelis virginiana leaf water.
[0022] Preferably, the preparation steps of Rosa rugosa flower extract, Artemisia argyi leaf extract, Citrus paradisi fruit extract, and Cassia obtusifolia extract are as follows: Put the washed rose petals, Artemisia argyi leaves, Citrus paradisi pulp, and Cassia obtusifolia seeds into an extraction tank, add clear water according to a solid - liquid ratio of 1:15 - 30, extract at a constant temperature of 50 - 100 °C for 0.5 - 12 hours. After extraction, use a filter to separate the solid residue to obtain a plant extract. Then, concentrate the plant extract to obtain a concentrated plant extract, and then perform a drying treatment to obtain Rosa rugosa flower extract, Artemisia argyi leaf extract, Citrus paradisi fruit extract, and Cassia obtusifolia extract.
[0023] An eye drop preparation device based on plant extracts, including an eye drop based on plant extracts as described above, which includes a preparation device main body, and also includes an auxiliary preparation cylinder, a movable plug, stirring blades and a stirring rod. Installation support arms are fixed on both the left and right sides of the preparation device main body. A balance base is fixed at the lower end of the installation support arm. A connecting bracket is fixed at the inner bottom end of the preparation device main body. An auxiliary preparation cylinder is arranged at the upper end of the connecting bracket. An air cylinder is installed at the inner top end of the auxiliary preparation cylinder. A piston rod is arranged at the lower end of the air cylinder. The lower end of the piston rod is connected to a movable plug. A connecting rod is fixed between two adjacent connecting brackets. A rotating shaft is connected to the surface of the connecting rod. Stirring blades are arranged on the surface of the rotating shaft. An adjustment chamber is arranged inside the auxiliary preparation cylinder. A mixing chamber is arranged between the auxiliary preparation cylinder and the preparation device main body. An output shaft is connected to the upper end of the preparation device main body. A driving motor is installed at the upper end of the output shaft. An annular and equally spaced extension arm is fixed at the lower end of the output shaft. A stirring rod is fixed at the lower end of the extension arm. Stirring blades are arranged on the surface of the stirring rod.
[0024] Preferably, there are four connecting brackets, and the central axis of the auxiliary preparation cylinder and the central axis of the preparation device main body are the same central axis.
[0025] Preferably, the movable plug is made of elastic rubber material, and the movable plug is slidably connected to the auxiliary preparation cylinder.
[0026] Preferably, there are four connecting rods, the connecting rods are rotatably connected to the rotating shaft, and stirring blades are fixed on the surface of the rotating shaft at equal intervals along the extension direction of the shaft.
[0027] Preferably, the stirring rods are arranged in one-to-one correspondence with the extension arms, and the extension direction of the stirring rods is perpendicular to the extension direction of the rotating shaft.
[0028] Preferably, a feed inlet is fixed at the upper end of the preparation device main body. A sealing plug is connected to the inside of the feed inlet. A control valve is installed at the lower end of the preparation device main body. A liquid outlet is connected to the lower end of the control valve.
[0029] The beneficial effects of the present invention:
[0030] 1. This plant extract-based eye drop combines the soothing and astringent properties of North American witch hazel leaf water, effectively relieving eye fatigue and reducing eye puffiness; 1,3-propylene glycol acts as a moisturizing factor to effectively maintain a moist environment on the ocular surface and reduce dryness; rose flower extract, with its rich antioxidant ingredients, can resist free radical damage and protect eye cells from damage; niacinamide and β-glucan not only enhance the eye barrier function, but also promote eye microcirculation and improve the phenomenon of dark circles; allantoin and dipotassium glycyrrhizinate, with their anti-inflammatory and soothing properties, help relieve eye inflammation and discomfort; and through the synergistic effects of wormwood extract, grapefruit fruit extract and cassia extract, further improve eye metabolism and enhance the antioxidant capacity of eye tissues. Compared with existing eye drops, this plant extract-based eye drop is not only more natural and safe, but also can significantly relieve discomfort symptoms such as eye fatigue, dryness, puffiness, etc., while strengthening the eye barrier, protecting the retina and promoting eye health.
[0031] 2. This kind of eye drops based on plant extracts and its preparation device, by opening an inlet and outlet channel that can connect the regulating chamber and the mixing chamber between two adjacent connecting brackets, using a movable plug to perform up and down reciprocating motion in the auxiliary preparation cylinder to achieve the suction or release of the prepared solution, effectively avoiding the occurrence of sinking to the bottom, and by arranging a plurality of rotatable stirring blades at the inlet and outlet channels, the mixing effect is further enhanced while the solution is replaced, which not only improves the preparation efficiency, but also ensures the full mixing of the raw materials and improves the product quality. BRIEF DESCRIPTION OF THE DRAWINGS
[0032] Figure 1 The three-dimensional structure of the present invention is shown in FIG. Figure 1 ;
[0033] Figure 2 Schematic diagram of the three-dimensional structure of the present invention Figure 2 ;
[0034] Figure 3 The cross-sectional three-dimensional structure of the present invention is shown in FIG. Figure 1 ;
[0035] Figure 4 The cross-sectional three-dimensional structure of the present invention is shown in FIG. Figure 2 ;
[0036] Figure 5 This is a schematic diagram of the three-dimensional structure of the auxiliary preparation tube of the present invention;
[0037] Figure 6 It is a schematic diagram of the three-dimensional structure of the auxiliary preparation tube cross section of the present invention.
[0038] Description of reference numerals in the drawings: 1. Main body of the preparation device; 2. Installation support arm; 3. Balanced base; 4. Connection bracket; 5. Auxiliary preparation cylinder; 6. Pneumatic cylinder; 7. Piston rod; 8. Movable plug; 9. Connecting rod; 10. Rotating shaft; 11. Stirring small blades; 12. Adjustment chamber; 13. Mixing chamber; 14. Output shaft; 15. Driving motor; 16. Extension arm; 17. Stirring rod; 18. Stirring large blades; 19. Feed inlet; 20. Sealing plug; 21. Control valve; 22. Liquid outlet. Detailed implementation manners
[0039] The present invention will be further described below with reference to the drawings and embodiments.
[0040] Please refer to Figures 1 - 6 , the present invention provides an embodiment: An eye drop based on plant extracts, comprising the following components in parts by weight:
[0041] 75.00 - 85.00 parts of water of Hamamelis virginiana leaves,
[0042] 4.00 - 8.00 parts of 1,3 - propanediol,
[0043] 2.00 - 6.00 parts of Rosa rugosa flower extract,
[0044] 0.50 - 1.50 parts of nicotinamide,
[0045] 0.50 - 1.50 parts of β - glucan,
[0046] 0.50 - 1.50 parts of lutein,
[0047] 0.2 - 0.7 parts of sodium chloride,
[0048] 0.10 - 0.30 parts of sodium hyaluronate,
[0049] 0.10 - 0.30 parts of allantoin,
[0050] 0.10 - 0.30 parts of dipotassium glycyrrhizinate,
[0051] 0.10 - 0.20 parts of Artemisia argyi leaf extract,
[0052] 0.10 - 0.20 parts of Citrus paradisi fruit extract,
[0053] 0.10 - 0.20 parts of Cassia obtusifolia extract,
[0054] Taurine: 2.50 - 7.00 parts.
[0055] Preferably, the preparation steps of witch hazel (HAMAMELIS VIRGINIANA) leaf water are as follows: Put the washed witch hazel leaves into a crusher for crushing to obtain crushed leaves with appropriate particle size. Then, add the crushed leaves and clear water to an extraction tank according to a solid-liquid ratio of 1:10-20, heat to 70-80 °C, and control the extraction time at 20-24 hours. After extraction, use a filter to separate the solid residue to obtain the witch hazel leaf water extract. Then, use the macroporous resin column purification method for purification. Next, concentrate the purified extract to obtain concentrated witch hazel leaf water.
[0056] Preferably, the preparation steps of rose (ROSA RUGOSA) flower extract, wormwood (ARTEMISIA ARGYI) leaf extract, grapefruit (CITRUS PARADISI) fruit extract, and cassia (CASSIA OB TUSIFOLIA) extract are as follows: Place the washed rose petals, wormwood leaves, grapefruit pulp, and cassia seeds in an extraction tank, add clear water according to a solid-liquid ratio of 1:15-30, and extract at a constant temperature of 50-100 °C for 0.5-12 hours. After extraction, use a filter to separate the solid residue to obtain the plant extract. Then, concentrate the plant extract to obtain the concentrated plant extract. Then, perform a drying treatment to obtain rose (ROSA RUGOSA) flower extract, wormwood (ARTEMISIA ARGYI) leaf extract, grapefruit (CITRUS PARADISI) fruit extract, and cassia (CASSIA OB TUSIFOLIA) extract.
[0057] An eye drop based on plant extracts and its preparation device, which includes a main body 1 of the preparation device, and also includes an auxiliary preparation cylinder 5, a movable plug 8, stirring blades 11, and a stirring rod 17. Installation arms 2 are fixed on both the left and right sides of the main body 1 of the preparation device. A balance base 3 is fixed at the lower end of the installation arm 2. A connecting bracket 4 is fixed at the inner bottom end of the main body 1 of the preparation device. An auxiliary preparation cylinder 5 is arranged at the upper end of the connecting bracket 4. An air cylinder 6 is installed at the inner top end of the auxiliary preparation cylinder 5. A piston rod 7 is arranged at the lower end of the air cylinder 6. The lower end of the piston rod 7 is connected to a movable plug 8. A connecting rod 9 is fixed between two adjacent connecting brackets 4. A rotating shaft 10 is connected to the surface of the connecting rod 9. Stirring blades 11 are arranged on the surface of the rotating shaft 10. An adjustment chamber 12 is arranged inside the auxiliary preparation cylinder 5. A mixing chamber 13 is arranged between the auxiliary preparation cylinder 5 and the main body 1 of the preparation device. An output shaft 14 is connected to the upper end of the main body 1 of the preparation device. A driving motor 15 is installed at the upper end of the output shaft 14. An annular and equally spaced extension arm 16 is fixed at the lower end of the output shaft 14. A stirring rod 17 is fixed at the lower end of the extension arm 16. Stirring blades 18 are arranged on the surface of the stirring rod 17.
[0058] Four connecting brackets 4 are provided. The central axis of the auxiliary preparation cylinder 5 and the central axis of the preparation device main body 1 are the same central axis. An inlet and outlet channel is formed between the auxiliary preparation cylinder 5 and the preparation device main body 1 through two adjacent connecting brackets 4 to realize the replacement of the solution.
[0059] The movable plug 8 is made of elastic rubber material. The movable plug 8 is slidably connected to the auxiliary preparation cylinder 5. The sliding connection method ensures the smooth movement of the movable plug 8 in the auxiliary preparation cylinder 5 to realize the suction or release of the preparation solution and avoid the phenomenon of sinking to the bottom.
[0060] Four connecting rods 9 are provided. The connecting rods 9 are rotatably connected to the rotating shaft 10. Stirring blades 11 are fixed on the surface of the rotating shaft 10 and are equally spaced along the extension direction of the shaft. By rotating the stirring blades 11 at the bottom end of the preparation device main body 1, it is helpful to realize the uniform mixing of the bottom materials and further prevent sinking to the bottom.
[0061] The stirring rods 17 and the extension arms 16 are provided in one-to-one correspondence. The extension direction of the stirring rods 17 is perpendicular to the extension direction of the rotating shaft 10. By longitudinally rotating a plurality of stirring rods 17, the raw materials in the mixing bin 13 can be mixed and stirred.
[0062] The upper end of the preparation device main body 1 is fixed with a feed inlet 19. A sealing plug 20 is connected to the inner side of the feed inlet 19. A control valve 21 is installed at the lower end of the preparation device main body 1. The lower end of the control valve 21 is connected to a liquid outlet 22. By providing the input and output interfaces of the preparation device, it is convenient for the addition of materials and the output of products, and at the same time ensures the hygiene and safety of the preparation process.
[0063] Example
[0064] An eye drop based on plant extracts, comprising the following components in parts by weight: Hamamelis virginiana leaf water 81.10, 1,3-propanediol 6.00, Rosa rugosa flower extract 4.00, niacinamide 1.00, β-glucan 1.00, lutein 1.00, sodium chloride 0.50, sodium hyaluronate 0.20, allantoin 0.20, dipotassium glycyrrhizinate 0.20, Artemisia argyi leaf extract 0.15, Citrus paradisi fruit extract 0.15, Cassia obtusifolia extract 0.15, taurine: 4.35.
[0065] The preparation steps are as follows:
[0066] First step, weigh each component according to the required ratio of the formula and set aside;
[0067] Step 2: Open the sealing plug 20, and add two-thirds of the Hamamelis virginiana leaf water, 1,3-propanediol, niacinamide, β-glucan, lutein, sodium chloride, sodium hyaluronate, allantoin, dipotassium glycyrrhizinate, and taurine into the main body 1 of the preparation device through the feed inlet 19. Then start the drive motor 15, and drive the extension arm 16 to rotate through the output shaft 14, so that the large mixing blades 18 on the mixing rod 17 can rotate in the mixing chamber 13, thereby realizing the preliminary stirring and mixing of the solution. Then start the pneumatic cylinder 6, and drive the movable plug 8 to move up and down in the auxiliary preparation cylinder 5 through the piston rod 7, so that the mixed liquid can flow back and forth between the mixing chamber 13 and the adjustment chamber 12 through the inlet and outlet channels between two adjacent connecting brackets 4, thereby realizing further mixing of the solution. At the same time, during the process of flow replacement of the solution, it will push the rotating shaft 10 to rotate on the connecting rod 9, so that a plurality of small mixing blades 11 can rotate at the bottom of the main body 1 of the preparation device, which helps to realize the uniform mixing of the bottom materials;
[0068] Step 3: Until the raw materials are fully mixed to form a basic solution. At this time, while stirring, slowly add the remaining one-third of the Hamamelis virginiana leaf water, Rosa rugosa flower extract, Artemisia argyi leaf extract, Citrus paradisi fruit extract, and Cassia obtusifolia extract into the basic solution until fully mixed to obtain the eye drops;
[0069] Step 4: Open the control valve 21, and discharge the prepared eye drops through the liquid outlet 22.
[0070] Through the above steps, through the carefully formulated plant extracts and other active ingredients, comprehensive care and soothing effects are provided for the eyes. The Hamamelis virginiana leaf water can effectively exert anti-inflammatory and astringent effects, relieve eye congestion, and enhance the antioxidant capacity of eye tissues through the synergistic effects among lutein, rose flower extract, artemisia leaf extract, grapefruit fruit extract, and cassia extract, so as to improve the overall eye health level. Moreover, more than 80% of the components are plant extracts, meeting the trend of "pure beauty", so as to solve the problems of poor metabolism of eye drops on the eyes, no obvious improvement in antioxidant capacity, and the problem that the eye drop preparation device is prone to sinking to the bottom, affecting the product quality.
[0071] The above has described the embodiments of the present invention in detail with reference to the drawings. However, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the scope of knowledge possessed by those skilled in the art.
Claims
1. An eye drop solution based on plant extracts, characterized in that: The composition comprises the following components in parts by weight: 75.00-85.00 parts of Hamamelis Virginiana leaf water, 4.00 to 8.00 parts of 1,3-propylene glycol, 2.00-6.00 parts of rose (ROSA RUGOSA) flower extract, 0.50-1.50 parts of niacinamide, β-glucan 0.50-1.50 parts, 0.50-1.50 parts of lutein, 0.2-0.7 parts of sodium chloride, 0.10-0.30 parts of sodium hyaluronate, Allantoin 0.10-0.30 parts, 0.10-0.30 parts of dipotassium glycyrrhizinate, Artemisia alginate leaf extract 0.10-0.20 parts, 0.10-0.20 parts of grapefruit (CITRUS PARADISI) fruit extract, Cassia (Cassia obtusifolia) extract 0.10-0.20 parts, Taurine: 2.50-7.00 parts.
2. The plant extract-based eye drops according to claim 1, characterized in that: The preparation steps of Hamamelis Virginiana leaf water are as follows: washing Hamamelis Virginiana leaves are put into a grinder for grinding to obtain broken leaves of suitable particle size, and then the broken leaves and clean water are added into an extraction tank according to a solid-liquid ratio of 1:10-20, heated to 70-80°C, and the extraction time is controlled within 20-24 hours. After the extraction is completed, the solid residue is separated by a filter to obtain the Hamamelis Virginiana leaf water extract, which is then purified by a macroporous resin column purification method, and then the purified extract is concentrated to obtain concentrated Hamamelis Virginiana leaf water.
3. The plant extract-based eye drops according to claim 1, characterized in that: The preparation steps of rose (ROSARUGOSA) flower extract, mugwort (ARTEMISIA ARGYI) leaf extract, grapefruit (CITRUS PARADISI) fruit extract and cassia (CASSIAOBTUSIFOLIA) extract are as follows: wash rose petals, mugwort leaves, grapefruit pulp and cassia seeds in an extraction tank, add clean water according to a solid-liquid ratio of 1:15-30, extract at a constant temperature of 50-100°C for 0.5-12 hours, after the extraction is completed, separate the solid residue with a filter to obtain a plant extract, then concentrate the plant extract to obtain a concentrated plant extract, and then dry it to obtain rose (ROSA RUGOSA) flower extract, mugwort (ARTEMISIA ARGYI) leaf extract, grapefruit (CITRUS PARADISI) fruit extract and cassia (CASSIAOBTUSIFOLIA) extract.
4. A device for preparing eye drops based on plant extracts, characterized in that The invention relates to an eye drop solution based on plant extracts according to claim 1, comprising a preparation device body (1), an auxiliary preparation cylinder (5), a movable stopper (8), a stirring blade (11) and a stirring rod (17), wherein mounting arms (2) are fixed to the left and right sides of the preparation device body (1), a balancing base (3) is fixed to the lower end of the mounting arms (2), a connecting bracket (4) is fixed to the inner bottom end of the preparation device body (1), an auxiliary preparation cylinder (5) is arranged at the upper end of the connecting bracket (4), a pneumatic cylinder (6) is installed at the inner top end of the auxiliary preparation cylinder (5), a piston rod (7) is arranged at the lower end of the pneumatic cylinder (6), a movable stopper (8) is connected to the lower end of the piston rod (7), and the two A connecting rod (9) is fixed between adjacent connecting brackets (4); a rotating shaft (10) is connected to the surface of the connecting rod (9); a small stirring blade (11) is arranged on the surface of the rotating shaft (10); an adjusting chamber (12) is arranged on the inner side of the auxiliary preparation cylinder (5); a mixing chamber (13) is arranged between the auxiliary preparation cylinder (5) and the preparation device body (1); an output shaft (14) is connected to the upper end of the preparation device body (1); a driving motor (15) is installed on the upper end of the output shaft (14); an annular equidistantly distributed extension arm (16) is fixed to the lower end of the output shaft (14); a stirring rod (17) is fixed to the lower end of the extension arm (16); and a large stirring blade (18) is arranged on the surface of the stirring rod (17).
5. A plant extract-based eye drop preparation device according to claim 4, characterized in that: Four connecting brackets (4) are provided, and the central axis of the auxiliary preparation cylinder (5) and the central axis of the preparation device main body (1) are the same central axis.
6. A plant extract-based eye drop preparation device according to claim 4, characterized in that: The movable plug (8) is made of elastic rubber material, and the movable plug (8) is slidably connected to the auxiliary preparation cylinder (5).
7. A plant extract-based eye drop preparation device according to claim 4, characterized in that: The connecting rod (9) is a U-shaped structure. Four connecting rods (9) are provided. The connecting rod (9) is rotatably connected to the rotating shaft (10). The surface of the rotating shaft (10) is fixed with stirring blades (11) equidistantly distributed along the extension direction of the shaft.
8. The device for preparing eye drops based on plant extracts according to claim 4, characterized in that: The stirring rod (17) and the extension arm (16) are arranged in a one-to-one correspondence, and the extension direction of the stirring rod (17) and the extension direction of the rotating shaft (10) are perpendicular to each other.
9. The device for preparing eye drops based on plant extracts according to claim 4, characterized in that: A feed port (19) is fixed at the upper end of the preparation device body (1), a sealing plug (20) is connected to the inner side of the feed port (19), a control valve (21) is installed at the lower end of the preparation device body (1), and a liquid outlet (22) is connected to the lower end of the control valve (21).