Medical DPF pig active remote monitoring isolation system

Abstract

The invention discloses a medical DPF pig active remote monitoring isolation system, and belongs to the technical field of animal isolation equipment, the medical DPF pig active remote monitoring isolation system comprises an isolation box for placing DPF pigs, a hollow mesh plate is arranged above the bottom in the isolation box, a feed bowl is detachably mounted on one side of the mesh plate, and a blow-off pipe is arranged at the bottom of the isolation box below the mesh plate; the two opposite sides of the isolation box are each fixedly provided with a cylinder, a DPF pig can penetrate through the cylinders to be placed into the isolation box, and a sealing plate is installed at an end opening of each isolation cylinder; an air inlet pipeline and an air outlet pipeline are further arranged on the isolation box, and the air inlet pipeline is connected with an air purification system so as to provide clean air for the isolation box; and a network camera capable of remotely checking the DPF pigs is mounted at the inner top of the isolation box. The medical DPF pig active remote monitoring and isolating system is compact in structure, reasonable in internal space design, convenient to move and use and good in monitoring and isolating maneuverability and flexibility.

Description

Technical Field

[0001] The present invention relates to the field of animal isolation equipment, and particularly to an active remote monitoring and isolation system for medical DPF pigs. Background Art

[0002] Medical DPF pigs can be used as models of human diseases to help scientists understand disease mechanisms and test new drugs and treatment methods. For example, by gene editing, piglets can be made to suffer from human-like diseases such as atherosclerosis, heart disease, liver injury, etc., providing a reference for the research and development of drugs and medical devices. Currently, medical DPF donor pigs play an important role in medical research and clinical applications. However, traditional monitoring and isolation methods have many deficiencies and cannot effectively isolate and protect DPF pigs. Especially when it is necessary to move DPF pigs, existing isolation devices are often fixedly installed in the laboratory and are immovable. If the DPF pigs are moved out of the laboratory, an additional clean and sterile environment needs to be provided to isolate them well from the outside. Moreover, the existing monitoring and isolation devices have insufficient integration, and fecal and sewage excretion requires separate docking and installation of excretion equipment. Therefore, during the movement process, the sewage disposal system and the air filtration system also need to be moved separately, which is very troublesome. In addition, when putting medical DPF donor pigs into the isolation device, they are put in from above the isolation device, which requires completely opening one side of the device, and the DPF pigs are prone to escape after being put in. Therefore, it is particularly important to develop a remote monitoring and isolation system with a simple and compact structure and easy to move. Summary of the Invention

[0003] The present invention aims at the defects of the prior art mentioned in the above background art, and thus proposes an active remote monitoring and isolation system for medical DPF pigs to solve the problems raised in the background art.

[0004] To solve the above technical problems, the present invention specifically provides the following technical solutions: The present invention provides an active remote monitoring and isolation system for medical DPF pigs, including an isolation box for placing DPF pigs. Above the bottom inside the isolation box, there is a hollowed-out mesh plate. On one side of the mesh plate, a feed bowl is detachably installed. At the bottom of the isolation box below the mesh plate, there is a sewage discharge pipe. On two opposite sides of the isolation box, a cylinder is respectively fixed. The cylinder can allow DPF pigs to pass through and be put into the isolation box. A sealing plate is installed at the port of each isolation cylinder. An air inlet pipe and an air outlet pipe are also provided on the isolation box. The air inlet pipe is connected to an air purification system to provide clean air for the isolation box. A network camera for remotely viewing DPF pigs is installed at the inner top of the isolation box.

[0005] Furthermore, a pair of through holes are provided on both the front and rear sides of the isolation box, and a sterile glove is connected to each through hole. The length of the sterile glove must be such that a person's hand can grab the DPF pig after inserting the glove.

[0006] Furthermore, the cylinder is horizontally installed on the side of the isolation box, and a cylindrical plastic film cylinder is provided inside the cylinder. The two ends of the plastic film cylinder are respectively turned outward and sleeved on the two ends of the cylinder, and the two ends of the plastic film cylinder are pressed by two fastening rings coaxially sleeved on the cylinder.

[0007] Furthermore, the end surface of the cylinder facing the isolation box has a rounded corner, so that the end surface interface of the cylinder wall of the cylinder is semicircular.

[0008] Furthermore, the two ends of the mesh plate are respectively fixed on a pair of support seats, the support seats are fixed on the inner bottom surface of the isolation box, and the support seats are in a right-angled trapezoidal structure, and their inclined surfaces are connected to one side of the top pipe opening of the sewage pipe; the inner bottom surface of the isolation box is an inclined surface, and the lower end of the inclined surface is connected to the other side of the sewage pipe.

[0009] Furthermore, a bearing ring is coaxially slidably disposed near the top end of the sewage pipe, and the central hole of the bearing ring includes a conical hole with the large end facing upward, and a fixing cone is coaxially disposed in the conical hole, and the fixing cone is fixedly connected to the feces receiving trough below the sewage pipe through a fixing rod; The bottom end of the bearing ring is mounted on the bearing plate through a pressure spring, and the bearing plate is vertically slidably connected to a guide plate vertically fixed to the bottom end of the bearing ring. In the assembled state, the pressure spring keeps the conical hole of the bearing ring in sealing contact with the fixed cone.

[0010] Furthermore, the top wall of the isolation box has a threaded hole, in which a cover plate and a threaded ring are threadedly fitted in sequence from top to bottom. A spherical shell-shaped transparent cover is fixed to the bottom end of the threaded ring. The network camera is installed in the area between the transparent cover and the cover plate, and the network camera is fixed on the cover plate.

[0011] Furthermore, the network camera is a spherical camera, and the mounting plate at the top of the spherical camera is connected to the cover plate bolts; and both sides of the top of the threaded ring sleeve are respectively provided with a slot.

[0012] Furthermore, a pair of mounting seats are fixed on both sides outside the bottom end of the threaded hole, and the two ends of the arched curved arm are rotatably mounted in the mounting seats, and a cleaning cotton strip is fixed on the inner side of the curved arm along its length direction. The end of the curved arm in one of the mounting seats is connected to a micro motor so that when the curved arm rotates, the cleaning cotton strip wipes the outer surface of the transparent cover.

[0013] Further, the micro-motor is fixed on a positioning plate, which is embedded in the top wall of the isolation box and is pressed by a pressing plate threadedly fitted on the isolation box, so that the driving gear on the main shaft of the micro-motor meshes with a driven gear at the end of the crank arm.

[0014] Compared with the current technology in this field, the present invention has the following series of beneficial effects: The overall design of the present invention is an upgrade on the idea of the sterile transfer isolator. The system occupies a small floor space, but the internal accommodation volume is increased, and it can transport small Bama pigs weighing 30 kg.

[0015] An air inlet and an air outlet are added, and an external air filtration system can be connected. A mobile power supply or a built-in power supply can be selected and placed in the control box to directly supply energy. With the assistance of universal wheels, it has the function of flexible movement.

[0016] In addition, the bottom of the isolation box in the present invention has a function of discharging fecal water, and the fecal water can be automatically discharged through a sewage discharge pipe. The temperature sensor in the present invention can be matched with the market temperature and humidity sensing and recording system, and is equipped with a display to view the recording curve. The whole machine has a detachable monitoring device and can remotely access the monitoring image. Moreover, the cylinder set in the present invention is used as the access structure, which is convenient for the smooth and rapid placement of the medical DPF donor pigs, and it is not easy to run out during the placement process. Moreover, the inlet and outlet are respectively at both ends of the isolation box, and the situation of taking out the pigs upside down will not occur. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the core technical solutions of the present invention, at least one embodiment based on the core concept of the present invention will be briefly introduced below, and if necessary, supplemented by the structural schematic diagrams required in the relevant prior art. Of course, the following drawings are only several feasible embodiments of the concept of the present invention. For those of ordinary skill in the art, without additional creative labor, some adaptable technical designs that may be represented can also be developed according to these drawings by themselves.

[0018] Figure 1 is a schematic external view of the present invention; Figure 2 is a cross-sectional view of the isolation box; Figure 3 is a partial cross-sectional view of the isolation box; Figure 4 is Figure 3 an enlarged view of the Y position in Figure 5 is Figure 2 an enlarged view of the M position in Figure 6 is a top view of the threaded collar; Figure 7 is a rotating tool for the threaded collar.

[0019] Description of reference numerals: isolation box 1, temperature sensor 2, mesh plate 3, sewage discharge pipe 4, cylinder 5, sterile gloves 6, intake pipe 7, outlet pipe 8, frame 9, control box 10, universal wheels 11, sealing plate 12, plastic film cylinder 13, fastening ring 14, bearing ring 15, fixed cone 16, fixed rod 17, pressure-bearing spring 18, mounting plate 19, guide plate 20, cover plate 21, threaded ring sleeve 22, network camera 23, transparent cover 24, cleaning cotton strip 25, curved arm 26, mounting seat 27, pressing plate 28, micro motor 29, driving gear 30, driven gear 31, slot 32, feces receiving trough 33, support seat 34. Detailed implementation manners

[0020] In order to make the purposes and functions that can be achieved by the creative features and technical means implemented by the present invention be more clearly understood, the related technical solutions of the present invention will be described in detail herein. Those of ordinary skill in the art should understand that the solutions described in all the following embodiments are just some feasible or recommended implementation structures or methods of the present invention, and not all the embodiments embodied by the present invention.

[0021] Those skilled in the art refer to Figure 1 As shown, this embodiment discloses a medical DPF pig active remote monitoring and isolation system. This isolation system is mainly improved on the basis of a sterile transfer isolator. Therefore, the functional designs of physiological parameters such as heart rate and temperature involved in monitoring will not be elaborated herein, as these functions are not the improvement points of this application and can be adaptively selected with reference to the prior art. The medical DPF pig active remote monitoring and isolation system in this embodiment mainly includes an isolation box 1 for placing DPF pigs. This isolation box 1 is generally in the structure of a rectangular parallelepiped box body, and a temperature sensor 2 is provided inside the isolation box 1. In specific practice, this isolation box 1 is installed on a frame 9 welded by stainless steel. Universal wheels 11 that can be locked are provided at the four corners of this frame 9 to facilitate movement and stand stably on the ground after moving into place. At the same time, a control box 10 for centrally displaying the temperature of the isolation box 1 and controlling ventilation is provided inside this frame 9, that is, all automatic control systems based on existing electrical controls are centrally installed in this control box 10. As another functional design, as Figure 2, above the bottom inside the isolation box 1, there is a perforated mesh plate 3 so that the fecal water of the DPF pigs can fall to the bottom of the isolation box 1, avoiding accumulation at the position where the DPF pigs stand. Moreover, at the bottom of the isolation box 1 below the mesh plate 3, there is a sewage discharge pipe 4 to centrally discharge the collected fecal water from the sewage discharge pipe 4. In addition, a feed bowl is detachably installed on one side of the mesh plate 3 to place feed and supplementary fruit jelly. And on two opposite sides of the isolation box 1, a cylinder 5 is respectively fixed. The cylinder 5 can allow the DPF pigs to pass through and be put into the isolation box 1. After the pigs are put into the isolation box 1 from one cylinder 5, they can be taken out from the other cylinder 5, avoiding the inconvenience when pouring the pigs. After the pigs are put into the isolation box 1, the sealing plates 12 installed at the ports of each isolation cylinder can be closed. For better ventilation, in this embodiment, an air inlet pipe 7 and an air outlet pipe 8 are also provided on the isolation box 1. The air inlet pipe 7 is connected to the air purification system, which can provide clean air for the isolation box 1 and maintain a clean environment. Moreover, in this embodiment, a network camera 23 capable of remotely viewing the DPF pigs is installed on the inner top of the isolation box 1, facilitating remote monitoring of the survival status of the DPF pigs. In addition, in order to operate the DPF pigs, a pair of perforations are provided on both the front and rear sides of the isolation box 1. A very long sterile glove 6 is connected to each perforation. The length of the sterile glove 6 must be such that after the human hand reaches into the glove, it can grab the DPF pigs to move the DPF pigs for observation.

[0022] For the convenience of putting the DPF pigs in, as Figure 2 - Figure 3 , the cylinder 5 can be horizontally installed on the side of the isolation box 1, and a cylindrical plastic film tube 13 is provided inside the cylinder 5. The two ends of the plastic film tube 13 are respectively turned outwards and sleeved at the two ends of the cylinder 5, and the two ends of the plastic film tube 13 are pressed by two fastening rings 14 coaxially sleeved on the cylinder 5, so that every time when entering and leaving the isolation box 1, stains are contaminated on the inner wall of the cylinder 5 and it is inconvenient to clean. During specific production, the end surface of one end of the cylinder 5 facing the inside of the isolation box 1 has a rounded corner, so that the end surface interface of the cylinder wall of the cylinder 5 is semi-circular. With such a design, the DPF pigs will not touch and scratch the port of the cylinder 5. In addition, it should be particularly noted that during specific production, a storage structure in the form of a storage box, for example, must be provided inside the above-mentioned isolation box 1. This storage box is mainly used to place feed and medicines, and a lock is installed on this storage box to prevent the pigs from opening the storage box.

[0023] As one of the specific implementation structures, as Figure 3 , both ends of this mesh plate 3 are respectively fixed on a pair of support seats 34. The support seats 34 are fixed on the inner bottom surface of the isolation box 1, and the support seats 34 are in the shape of a right-angled trapezoid, and its inclined surface is connected to one side of the top pipe orifice of the sewage discharge pipe 4, facilitating the fecal water to flow down smoothly. Moreover, the inner bottom surface of this isolation box 1 is also correspondingly designed as an inclined surface, and the low-end side of the inclined surface is connected to the other side of the sewage discharge pipe 4, so that the fecal water naturally flows into the sewage discharge pipe 4 for discharge.

[0024] In order to keep the sewage discharge pipe 4 normally closed when there is no fecal water discharge, as Figure 4 , a bearing ring 15 slides coaxially at the top port of the sewage discharge pipe 4. The central hole of this bearing ring 15 includes a conical hole with the large end facing up, and the lower hole section can be a cylindrical hole. A fixed cone 16 is coaxially arranged in the conical hole. The fixed cone 16 is fixedly connected to the feces receiving tank 33 below the sewage discharge pipe 4 through a fixing rod 17. More specifically, the bottom end of the bearing ring 15 is installed on a bearing plate through a pressure-bearing spring 18. The pressure-bearing spring 18 can be a conical spring, and the bearing plate is vertically slidably connected to a guide plate 20 vertically fixed at the bottom end of the bearing ring 15 to guide the vertical sliding of the bearing ring 15 and shield and protect the conical spring. Moreover, in the assembled state of the device, the pressure-bearing spring 18 makes the conical hole of the bearing ring 15 keep sealing contact with the fixed cone 16 to maintain normal closure. When the fecal water at the bottom of the isolation box 1 accumulates to a certain amount, the bearing ring 15 moves vertically downward, compressing the pressure-bearing spring 18, and the bearing ring 15 moves downward accordingly, separating from the above-mentioned fixed cone 16. The fecal water flows down through the gap exposed between the fixed cone 16 and the bearing ring 15 and then is discharged. When the discharge reaches a certain amount, based on the pushing and resetting action of the conical spring, the bearing ring 15 moves vertically upward to reset and makes sealing contact with the fixed cone 16 to restore the sealing of the sewage discharge pipe 4.

[0025] As a specific embodiment, when the above-mentioned network camera 23 is specifically installed, as Figure 2 , there is a threaded hole in the top wall of the isolation box 1. A cover plate 21 and a threaded ring sleeve 22 are sequentially threadedly engaged in this threaded hole from top to bottom. Moreover, at the bottom end of the threaded ring sleeve 22, a spherical transparent cover 24 is fixed. Inside the area between the transparent cover 24 and the cover plate 21, a network camera 23 is installed, and the network camera 23 is fixed on the cover plate 21 to implement monitoring of the DPF pigs in the isolation box 1, and the transparent cover 24 plays a role in protecting the camera. Specifically, the network camera 23 is a spherical camera. The mounting plate 19 at the top end of the spherical camera is bolted to the cover plate 21 to achieve detachable installation. As Figure 5 - Figure 6 shown, there is a slot 32 on each side of the top end of the threaded ring sleeve 22, so that a rotating tool as Figure 7 shown can be directly inserted to rotate the threaded ring sleeve 22.

[0026] For a more specific design structure, please refer to Figure 5, on both sides outside the bottom end of the threaded hole, a pair of mounting seats 27 are fixed. The two ends of a crank arm 26 are rotatably mounted in the two mounting seats 27. This crank arm 26 arches downward. Along its length direction, a cleaning cotton strip 25 is fixed to the inner side of the crank arm 26 so as to contact the outer surface of the transparent cover 24. During installation, the end of the crank arm 26 in one of the mounting seats 27 can be in transmission connection with a micro motor 29. By controlling the rotation of the micro motor 29, the crank arm 26 can be rotated, and then the cleaning cotton strip 25 can wipe the outer surface of the transparent cover 24, realizing the cleaning of the transparent cover 24 and avoiding affecting the clear monitoring of the DPF pig.

[0027] Based on the above structure, as Figure 5 shown, the micro motor 29 is fixed on a positioning plate. The positioning plate is embedded in the top wall of the isolation box 1 and is pressed by a pressing plate 28 threadedly fitted on the isolation box 1, so as to realize the installation and positioning of the micro motor 29. Indirectly, the driving gear 30 on the main shaft of the micro motor 29 accurately meshes with a driven gear 31 at the end of the crank arm 26. While ensuring quick installation, the reliability of the gear transmission is ensured.

[0028] Finally, it should be particularly noted that in all the content recorded in the present invention, such as the terms "including", "comprising", and other general statements, are all based on the non-exclusive inclusion of technologies, so that the processes, articles, methods, or related devices of the corresponding elements all mean not only including these technical elements, but also the inherent characteristics of a certain process, article, device, and method.

[0029] As those of ordinary skill in the art should clearly know, any person familiar with the technical field of the present technology can, on the basis of fully understanding the technical principle of the present invention, make adaptive improvement designs or equivalent replacements based on the above embodiments. Thus, several technical solutions that do not depart from the core technical concept of the present invention should essentially be included within the protection scope of the present invention.

Claims

1. A medical DPF pig active remote monitoring isolation system, comprising an isolation box (1) for accommodating a DPF pig, wherein a temperature sensor (2) is arranged in the isolation box (1), and characterized in that: A hollow mesh plate (3) is provided above the bottom of the isolation box (1), a feed bowl is detachably mounted on one side of the mesh plate (3), and a sewage pipe (4) is provided at the bottom of the isolation box (1) below the mesh plate (3); a cylinder (5) is fixed to each of the two opposite sides of the isolation box (1), the cylinder (5) can allow the DPF pig to pass through and be placed in the isolation box (1), and a sealing plate (12) is installed at the port of each isolation cylinder; The isolation box (1) is also provided with an air inlet duct (7) and an air outlet duct (8), and the air inlet duct (7) is connected to an air purification system to provide clean air for the isolation box (1); a network camera (23) capable of remotely viewing the DPF pig is installed on the inner top of the isolation box (1).

2. According to claim 1, a medical DPF pig active remote monitoring isolation system is characterized by: The isolation box (1) is installed on a frame (9), and the four corners of the frame (9) are provided with universal wheels (11) that can be locked. The frame (9) is provided with a control box (10) for centrally displaying the temperature of the isolation box (1) and controlling ventilation. A pair of through holes are provided on the front and rear sides of the isolation box (1), and each through hole is connected to a sterile glove (6). The length of the sterile glove (6) is required to enable a person to grab a DPF pig after inserting a hand into the glove.

3. The medical DPF pig active remote monitoring isolation system according to claim 1 is characterized by: The cylinder (5) is horizontally mounted on the side of the isolation box (1), and a cylindrical plastic film cylinder (13) is arranged inside the cylinder (5). The two ends of the plastic film cylinder (13) are respectively turned outward and sleeved on the two ends of the cylinder (5), and the two ends of the plastic film cylinder (13) are pressed by two fastening rings (14) coaxially sleeved on the cylinder (5).

4. The medical DPF pig active remote monitoring isolation system according to claim 3 is characterized by: The end surface of the cylinder (5) facing the isolation box (1) has a rounded corner, so that the end surface interface of the cylinder wall of the cylinder (5) is semicircular; a storage box is provided inside the isolation box (1), the storage box is used to place feed and medicine, and a lock is installed on the storage box.

5. The medical DPF pig active remote monitoring isolation system according to claim 1 is characterized by: The two ends of the mesh plate (3) are respectively fixed on a pair of support seats (34), and the support seats (34) are fixed on the inner bottom surface of the isolation box (1). The support seats (34) are in a right-angled trapezoidal structure, and their inclined surfaces are connected to one side of the top pipe opening of the sewage pipe (4); the inner bottom surface of the isolation box (1) is an inclined surface, and the lower end of the inclined surface is connected to the other side of the sewage pipe (4).

6. A medical DPF pig active remote monitoring isolation system according to claim 5, characterized in that: The sewage pipe (4) is coaxially slidably provided with a bearing ring (15) near its top end, the center hole of the bearing ring (15) comprises a conical hole with the large end facing upward, a fixing cone (16) is coaxially arranged in the conical hole, and the fixing cone (16) is fixedly connected to the feces receiving trough (33) below the sewage pipe (4) through a fixing rod (17); The bottom end of the bearing ring (15) is mounted on a bearing plate via a pressure spring (18), and the bearing plate is vertically slidably connected to a guide plate (20) vertically fixed to the bottom end of the bearing ring (15). In the assembled state, the pressure spring (18) enables the conical hole of the bearing ring (15) to maintain sealing contact with the fixed cone (16).

7. The medical DPF pig active remote monitoring isolation system according to claim 1 is characterized by: The top wall of the isolation box (1) has a threaded hole, in which a cover plate (21) and a threaded ring sleeve (22) are threadedly engaged in sequence from top to bottom, a spherical shell-shaped transparent cover (24) is fixed to the bottom end of the threaded ring sleeve (22), and the network camera (23) is installed in the area between the transparent cover (24) and the cover plate (21), and the network camera (23) is fixed on the cover plate (21).

8. The medical DPF pig active remote monitoring isolation system according to claim 7 is characterized by: The network camera (23) is a spherical camera, and the mounting plate (19) at the top of the spherical camera is bolted to the cover plate (21); and the top two sides of the threaded ring sleeve (22) each have a slot (32).

9. The medical DPF pig active remote monitoring isolation system according to claim 7 is characterized by: A pair of mounting seats (27) are fixed on both sides outside the bottom end of the threaded hole, and two ends of an arched curved arm (26) are rotatably mounted in the mounting seats (27). A cleaning cotton strip (25) is fixed on the inner side of the curved arm (26) along its length direction, and an end of the curved arm (26) in one of the mounting seats (27) is transmission-connected to a micro motor (29) so that when the curved arm (26) rotates, the cleaning cotton strip (25) wipes the outer surface of the transparent cover (24).

10. The medical DPF pig active remote monitoring isolation system according to claim 9 is characterized in that: The micro motor (29) is fixed on a positioning plate, which is embedded in the top wall of the isolation box (1) and is pressed by a pressing plate (28) threadedly mounted on the isolation box (1), so that a driving gear (30) on the main shaft of the micro motor (29) is kept in mesh with a driven gear (31) at the end of the crank arm (26).

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