Conveyor and conveying system

Abstract

The invention relates to a conveyor and a conveying system, the conveyor is used for conveying a self-expanding implant, the conveyor comprises an operating rod, a binding structure and a loading sheath, the binding structure comprises a binding part, the binding part sleeves the outer side of the operating rod and is connected with the operating rod, the loading sheath movably sleeves the operating rod, and in a loading state, the binding part is connected with the loading sheath; the operating rod is used for bearing an implant, the constraining part is used for being arranged at the far end of the implant in a sleeving mode, and the implant and the constraining part are both located in an inner cavity of the loading sheath; when the loading sheath moves along the operating rod until the implant and the binding part are exposed, the far end of the implant is bound by the binding part in the radial direction and is in an incomplete release state, and the radial size of the part, bound by the binding part in the radial direction, of the implant is larger than the outer diameter of the loading sheath. The conveyor provided by the invention can improve the positioning precision of the implant.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a delivery device and a delivery system. Background Art

[0002] The information provided in this section is only background information related to the present disclosure, and it is not necessarily prior art.

[0003] In endovascular exclusion, an implant is generally delivered to the lesion site through a delivery device. For example, when treating aortic dissection or aortic aneurysm, a covered stent is delivered to the corresponding part through a delivery device, and then the covered stent is released at the lesion site to cover the lesion site, so as to prevent blood flow from entering the dissection or aneurysm cavity, thereby achieving the purpose of treatment. However, in the prior art, the positioning accuracy of the implant during implantation is poor. Summary of the Invention

[0004] Based on this, it is necessary to provide a delivery device that can improve the positioning accuracy of the implant.

[0005] Furthermore, a delivery system that can improve the positioning accuracy of the implant is provided.

[0006] A delivery device for delivering a self-expanding implant, comprising: an operating rod, a restraint structure, and a loading sheath. The restraint structure includes a restraint portion that is sleeved outside the operating rod and connected to the operating rod. The loading sheath is movably sleeved on the operating rod. In the loading state, the operating rod is used to carry the implant, the restraint portion is used to sleeve the distal end of the implant, and both the implant and the restraint portion are located in the inner cavity of the loading sheath; when the loading sheath moves along the operating rod to expose the implant and the restraint portion, the distal end of the implant is radially restrained by the restraint portion and is in an incompletely released state, and the radial dimension of the portion of the implant radially restrained by the restraint portion is greater than the outer diameter of the loading sheath.

[0007] A delivery system includes an implant and the above-mentioned delivery device. In the loading state, the implant is sleeved on the operating rod, the restraint portion is sleeved on the distal end of the implant, and both the implant and the restraint portion are located in the inner cavity of the loading sheath; when the loading sheath moves along the operating rod to expose the implant and the restraint portion, the distal end of the implant is radially restrained by the restraint portion and is in an incompletely released state, and the radial dimension of the portion of the implant radially restrained by the restraint portion is greater than the outer diameter of the loading sheath.

[0008] The above conveyor is used to load and convey the implant. In the loading state, the operating rod is used to carry the implant, the binding part is used to sleeve the distal end of the implant, and both the implant and the binding part are located in the inner cavity of the loading sheath, so as to facilitate the conveyance of the implant in the body of the implant recipient. When reaching the expected position, when the loading sheath is operated to move along the operating rod to expose the implant and the binding part, the distal end of the implant is radially bound by the binding part and is not in a completely released state. In this state, the radial dimension of the radially constrained part of the bound part of the implant is larger than the outer diameter of the loading sheath. Therefore, compared with the state where the implant is completely radially bound and received in the loading sheath, the radial dimension of the distal end of the implant is closer to the dimension in the implanted state, and the positioning accuracy of the implant at a dimension closer to the implanted state is more accurate. Moreover, in this state, the distal end of the implant is not completely released and is in a state of not completely adhering to the wall. If it is found that the position of the implant does not meet the requirements during the positioning process of the implant, the position of the implant can still be adjusted to meet the requirements. Thus, using this conveyor to convey the implant can improve the positioning accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0009] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the following drawings are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0010] Wherein:

[0011] Figure 1 is a state diagram of the conveyor loading the implant in an embodiment;

[0012] Figure 2 is a schematic structural diagram of the implant in an embodiment;

[0013] Figure 3 is a schematic structural diagram of the conveyor in an embodiment;

[0014] Figure 4A is a perspective view of the end head, operating rod and binding structure in an embodiment, wherein the binding structure is in a state of being radially supported;

[0015] Figure 4B is a schematic structural diagram of the end head, operating rod and binding structure in an embodiment, wherein the binding structure is in a state of being radially supported;

[0016] Figure 5 is a first state diagram during the process of loading the implant into the conveyor;

[0017] Figure 6The second state diagram during the process of loading an implant into a delivery device;

[0018] Figure 7 The third state diagram during the process of loading an implant into a delivery device;

[0019] Figure 8 The fourth state diagram during the process of loading an implant into a delivery device;

[0020] Figure 9 The first state diagram during the process of implanting an implant into a blood vessel through a delivery device;

[0021] Figure 10 The second state diagram during the process of implanting an implant into a blood vessel through a delivery device;

[0022] Figure 11 The third state diagram during the process of implanting an implant into a blood vessel through a delivery device;

[0023] Figure 12 The fourth state diagram during the process of implanting an implant into a blood vessel through a delivery device;

[0024] Figure 13 The fifth state diagram during the process of implanting an implant into a blood vessel through a delivery device;

[0025] Figure 14A The state diagram when loading an implant into a delivery device in another embodiment;

[0026] Figure 14B The perspective view of a restraint structure in a radially expanded state in one embodiment. In Figure 14B To show the cylindrical mesh structure, the covering is hidden;

[0027] Figure 14C The schematic structural diagram of a restraint structure in a radially expanded state in one embodiment. In Figure 14C To show the cylindrical mesh structure, the covering is hidden;

[0028] Figure 15 The schematic structural diagram of a restraint structure in a radially expanded state in another embodiment. Detailed implementation manners

[0029] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0030] In the description of the embodiments of the present invention, it should be noted that for the orientation or positional relationship indicated by terms such as "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., it is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the embodiments of the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, so it cannot be understood as a limitation to the embodiments of the present invention. In addition, the terms "first", "second", and "third" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0031] In the description of the embodiments of the present invention, it should be noted that unless otherwise clearly specified and limited, the terms "installation", "connection", and "connection" should be understood in a broad sense. For example, it can be a fixed connection, a replaceable connection, or an integral connection. It can be a mechanical connection or an electrical connection. It can be directly connected or indirectly connected through an intermediate medium. It can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the embodiments of the present invention can be understood according to specific situations.

[0032] In the field of interventional medical devices, generally, the end of the medical device implanted into the human body or animal body that is closer to the operator is called the "proximal end", and the end that is farther from the operator is called the "distal end", and the "proximal end" and "distal end" of any component of the medical device are defined based on this principle. The "axial direction" generally refers to the length direction of the medical device when it is being delivered, and the "radial direction" generally refers to the direction of the medical device that is not parallel to its "axial direction", and the "axial direction" and "radial direction" of any component of the medical device are defined based on this principle. The "circumferential direction" refers to the circumferential direction, that is, the direction around the axis of the lumen structure or the column.

[0033] The technical solution of the embodiments of the present application is to solve the problem of poor positioning accuracy of the implant during implantation. The general idea is as follows:

[0034] Provide a delivery device. A restraint structure is provided on the operating rod of the delivery device. During the process of releasing the implant, the restraint structure can restrain at least a part of the implant. The part of the implant restrained by the restraint structure is in a semi-released state. The size of the implant in the semi-released state is closer to the size in the implanted state. Therefore, the positioning accuracy of the implant in the semi-released state is higher.

[0035] To better understand the above technical solution, the above technical solution will be described in detail below in conjunction with the accompanying drawings of the specification and specific embodiments.

[0036] First Embodiment

[0037] Please refer to Figure 1, the present disclosure provides a delivery system A, including a delivery device 100 and an implant 800. The delivery device 100 is used to deliver the implant 800. The implant 800 can be a covered stent, a filter, an artificial valve or other self-expanding implants. In this embodiment, the implant 800 is taken as an example of a covered stent for illustration.

[0038] Please refer to Figure 2 , the implant 800 includes a tubular covering film 810 and a plurality of corrugated rings 820 arranged on the covering film 810. The material of the covering film 810 can be biocompatible materials such as PTFE (polytetrafluoroethylene) or PET (polyethylene terephthalate). The covering film 810 can isolate the blood flow. When the implant 800 is implanted into the lesion site, it can isolate the blood flowing to the lesion site, thereby preventing blood from flowing into the dissection or aneurysm cavity. The material of the corrugated rings 820 can be other shape memory metal materials such as nitinol alloy. The plurality of corrugated rings 820 are arranged axially and connected to the covering film 810, so that the implant 800 can self-expand. The adjacent two corrugated rings 820 can be connected to each other by interlocking or through the covering film 810. When the corrugated rings 820 are subjected to a radial compressive force, the corrugated rings 820 can radially contract and deform. When the external force is withdrawn, the corrugated rings 820 can radially self-expand, so that the implant 800 can be radially compressed to a smaller loading state and can self-expand to a larger implantation state.

[0039] Please refer to Figure 3 , the delivery device 100 includes an operating rod 11, a restraint structure 20 and a loading sheath 31. The restraint structure 20 is connected to the operating rod 11, and the loading sheath 31 is movably sleeved on the operating rod 11.

[0040] Please refer to Figure 1 and Figure 3 For convenience of description, a partial area at the distal end of the operating rod 11 is defined as a loading section 111 for loading the implant 800.

[0041] Please refer to Figure 1 and Figure 3 , the loading sheath 31 is movably sleeved on the operating rod 11. The loading sheath 31 can axially move relative to the operating rod 11 between a first position and a second position under the action of an external force. When the loading sheath 31 is in the first position, the loading sheath 31 completely covers the loading section 111 and compresses and loads the restraint structure 20 and the implant 800 in its lumen; when the loading sheath 31 is in the second position, the loading sheath 31 is radially offset from the loading section 111, so as to cancel the radial compression of the restraint structure 20 and the implant 800, and expose the restraint structure 20 and the implant 800.

[0042] Please refer to Figure 1 , Figure 4A and Figure 4B, in this embodiment, the restraint structure 20 includes a restraint portion 21 and a connecting portion 22. The restraint portion 21 is sleeved outside the operating rod 11. One end of the connecting portion 22 is connected to the operating rod 11, and the other end of the connecting portion 22 is connected to the restraint portion 21, so that the restraint portion 21 is connected to the operating rod 11. In other embodiments, the connecting portion 22 of the restraint structure 20 can be omitted. After omitting the connecting portion 22, the restraint portion 21 is directly connected to the operating rod 11. The restraint portion 21 and the connecting portion 22 in this embodiment are flexible.

[0043] Please refer to Figure 1 , when the implant 800 is loaded in the transporter 100, the loading sheath 31 is in the first position. The operating rod 11 is used to carry the implant 800. The implant 800 is detachably sleeved on the loading section 111. The restraint portion 21 is sleeved on the distal end of the implant 800. The restraint portion 21, the connecting portion 22, and the implant 800 are all compressed in the inner cavity of the loading sheath 31 for transportation in the body cavity of the implantation object.

[0044] When reaching the desired position, by applying a force to the loading sheath 31. The loading sheath 31 axially moves relative to the operating rod 11 to the second position under the action of the external force. When the loading sheath 31 moves to expose a part of the restraint portion 21 and the implant 800, the radial restraint on the restraint portion 21 disappears, but the distal end of the implant 800 is still in the state of being restrained by the restraint portion 21, and a part of the proximal end of the implant 800 is still radially restrained by the loading sheath 31 and is in an incompletely released state. In this state, the radial dimension of the part of the implant 800 radially constrained by the restraint portion 21 is larger than the outer diameter of the loading sheath 31. Thus, the radial dimension of the part of the implant 800 radially restrained by the restraint portion 21 is smaller than the radial dimension of the implant 800 in the implanted state. Therefore, this state is defined as a semi-released restraint state. (The semi-released restraint state can be seen in Figure 10 , which will be introduced in detail later).

[0045] The distal end of the implant 800 is in an incompletely released state. The radial dimension of the part of the implant 800 radially restrained by the restraint portion 21 is smaller than its radial dimension in the implanted state. In this state, the radial dimension of the part of the implant 800 semi-released and restrained by the restraint portion 21 is larger than the outer diameter of the loading sheath 31, so that the radial dimension of the part of the implant 800 restrained by the restraint portion 21 is closer to the dimension in the implanted state. The positioning accuracy of the implant 800 is more accurate at a dimension closer to the implanted state. If it is found that the position of the implant 800 does not meet the requirements during the positioning process of the implant 800, since the implant 800 has not adhered to the wall yet, the position of the implant 800 can still be adjusted to meet the requirements. Thus, using the transporter 100 to transport the implant 800 can improve the positioning accuracy.

[0046] When the positioning of the implant 800 is completed, a force is applied to the loading sheath 31 so that the loading sheath 31 axially moves relative to the operating rod 11 to a second position to completely release the proximal end of the implant 800, such that only the distal portion of the implant 800 is semi-released and constrained by the constraining portion 21. See this state in Figure 11 , which will be described in detail later).

[0047] When it is necessary to completely release the implant 800, the operating rod 11 is moved relative to the implant 800 such that the operating rod 11 drives the constraining portion 21 to move, so that the constraining portion 21 is separated from the implant 800, thereby completely releasing the implant 800.

[0048] During the process of releasing the implant 800, after the constraining portion 21 is separated from the implant 800 in the semi-released and constrained state, the implant 800 self-expands from the semi-released and constrained state to a state where it abuts against the blood vessel wall. Since the size of the implant 800 in the semi-released and constrained state is closer to the diameter in the implanted state than the size when loaded in the loading sheath 31, compared with the solution of self-expanding from the size when loaded in the loading sheath 31 to abut against the blood vessel wall, in this embodiment, self-expanding from the size in the semi-released and constrained state to abut against the blood vessel wall can reduce the irritation to the blood vessel wall when the implant 800 abuts against the blood vessel wall.

[0049] In one embodiment, when the loading sheath 31 moves along the operating rod 11 to expose the implant 800 and the constraining portion 21, and the distal end of the implant 800 is radially constrained by the constraining portion 21 and is in an incompletely released state, the radial dimension of the portion of the implant 800 radially constrained by the constraining portion 21 is greater than the outer diameter of the loading sheath 31, and the diameter of the constraining portion 21 is 30% - 75% of the diameter of the implant 800 in the natural state, so that the radial dimension of the portion of the implant 800 constrained by the constraining portion 21 is closer to the dimension in the implanted state. Positioning the implant 800 at a dimension closer to the implanted state can improve the positioning accuracy.

[0050] Please refer to Figure 3 , in this embodiment, the operating rod 11 is a tubular structure, and the operating rod 11 has a guide wire cavity (not shown in the figure) for the guide wire to penetrate. The delivery device 100 of this embodiment further includes an operating member 12, and the operating member 12 is connected to the proximal end of the operating rod 11 to facilitate the operator to hold the operating member 12 outside the body, and further facilitate the operation of the operating rod 11. The operating member 12 is provided with a through hole (not shown in the figure) communicating with the guide wire cavity, and the guide wire can enter the guide wire cavity after passing through the through hole.

[0051] Please refer to Figure 3, the conveyor 100 of this embodiment further includes a holding portion 32. The holding portion 32 is connected to the proximal end of the loading sheath 31 to facilitate the operator to hold the holding portion 32, thereby facilitating the operation of the loading sheath 31 outside the body of the implant recipient. The holding portion 32 is provided with a perforation communicating with the inner cavity of the loading sheath 31 to facilitate the operating rod 11 to pass through and extend into the inner cavity of the loading sheath 31.

[0052] Please refer to Figure 4A and Figure 4B , the conveyor 100 further includes a tip 41. The tip 41 is connected to the distal end of the operating rod 11. The tip 41 has an axial hole (not shown in the figure) that is the same as the guide wire cavity of the operating rod 11 for the guide wire to pass through. The radial dimension of the distal portion of the tip 41 gradually increases in the direction from the distal end to the proximal end. When the conveyor 100 enters the body of the implant recipient through the puncture port, the tip 41 can play a role in guiding the puncture. When it is necessary to load the implant 800, the loading sheath 31 and the tip 41 move relative to each other and move away from each other to open the inner cavity of the loading sheath 31 and expose the loading section 111; when the loading of the implant 800 is completed, the loading sheath 31 and the tip 41 approach each other and abut against each other, so that the distal opening of the loading sheath 31 is sealed by the tip 41, thereby compressing and loading the implant 800 in the inner cavity of the loading sheath 31 to facilitate the delivery of the implant 800 in the body of the implant recipient.

[0053] Please refer to Figure 4A and Figure 4B , in one embodiment, the restraint portion 21 is formed of a flexible material, and the flexible material encloses a cylindrical structure. When the implant 800 is implanted and the loading sheath 31 is pushed distally, since the restraint portion 21 is flexible, the loading sheath 31 can squeeze and deform the restraint portion 21 and re-receive the restraint portion 21 into its inner cavity to facilitate the withdrawal of the conveyor 100 from the body. It should be noted that since the restraint portion 21 in this embodiment is a cylindrical structure made of a flexible material, the restraint portion 21 is in a collapsed state when in the natural state without external force (as shown in Figure 5 ), in order to more clearly show the structure of the restraint structure 20, the structure of the restraint structure 20 when receiving radial support is shown in Figure 4A and Figure 4B . In other embodiments, the connecting portion 22 and the restraint portion 21 have a certain flexibility, but in the natural state without external force, the restraint portion 21 can present a three-dimensional form as shown in Figure 4A and Figure 4B , and the radial dimension of the restraint portion 21 is larger than the outer diameter of the loading sheath 31, so that after the implant 800 is implanted and the loading sheath 31 moves in the direction close to the tip 41 and enters the restraint portion 21, when the loading sheath 31 continues to move closer to the tip 41, it can drive the restraint structure 20 to flip to a certain extent and can re-receive the restraint structure 20 into its inner cavity.

[0054] In one embodiment, the flexible material forming the restraint portion 21 has lubricity. For example, the material may be at least one of polytetrafluoroethylene (PTFE), polyurethane (PU), and polyester, such that the restraint portion 21 has lubricity. When the loading sheath 31 moves proximally relative to the implant 800 to expose the implant 800 and the restraint portion 21, the frictional resistance between the outer surface of the restraint portion 21 and the loading sheath 31 can be reduced, thereby reducing the release resistance.

[0055] In this embodiment, the connecting portion 22 is flexible, such that the connecting portion 22 can be deformed under an external force. During the process of releasing the implant 800, the restraint portion 21 is radially supported by the implant 800, and one end of the connecting portion 22 connected to the restraint portion 21 is driven by the restraint portion 21 to expand outward (i.e., there is a radial distance between the outer surface of the operating rod 11), so that the radial distance between the connecting portion 22 and the outer surface of the operating rod 11 gradually increases from the end of the connecting portion 22 connected to the operating rod 11 to the end of the connecting portion 22 connected to the restraint portion 21. When it is necessary to separate the restraint portion 21 from the implant 800, by rotating the operating rod 11, the end of the connecting portion 22 connected to the operating rod 11 can be rotated synchronously with the operating rod 11, while the end of the connecting portion 22 connected to the restraint portion 21 is jointly restricted by the restraint portion 21 and the implant 800, such that the end of the connecting portion 22 connected to the restraint portion 21 cannot rotate synchronously with the operating rod 11, thereby causing the connecting portion 22 to be twisted and wound around the operating rod 11. During this process, the connecting portion 22 pulls the restraint portion 21 distally, that is, the connecting portion 22 drives the restraint portion 21 to move distally until the restraint portion 21 is separated from the implant 800. Since the connecting portion 22 of this embodiment is flexible, the transporter 100 can separate the restraint structure 20 from the implant 800 by rotating the operating rod 11. Separating the restraint structure 20 from the implant 800 by rotating the operating rod 11 can avoid the risk of the operating rod 11 axially moving and puncturing the lumen wall. Especially when the implant 800 needs to be delivered to a curved body cavity (such as the aortic arch), by using the transporter 100 of this embodiment, the operating rod 11 can be prevented from puncturing the body cavity wall.

[0056] It should be noted that regardless of whether the connecting portion 22 is flexible, when it is necessary to operate the separation of the restraint portion 21 from the implant 800, the method of axially moving the operating rod 11 distally can also be adopted. The operating rod 11 drives the connecting portion 22 and the restraint portion 21 to move distally, which can separate the restraint portion 21 from the implant 800. In this case, to avoid puncturing the blood vessel wall, the end 41 is a flexible structure.

[0057] The material of the connecting portion 22 can be at least one of polytetrafluoroethylene (PTFE), polyurethane (PU), and polyester. The material of the connecting portion 22 can be the same as or different from that of the binding portion 21.

[0058] Please refer to Figure 4A and Figure 4B , a plurality of through holes 221 are provided on the connecting portion 22, and the through holes 221 communicate with the inner cavity of the binding portion 21. When the implant 800 is bound by the binding portion 21, the through holes 221 communicate with the inner cavity of the implant 800. In a state where the distal end of the implant 800 is radially bound by the binding portion 21 and the rest is released (as shown in Figure 11 ), blood can flow into the inner cavity of the implant 800 along the through holes 221 of the connecting portion 22, and then flow downstream through the proximal opening of the implant 800 to ensure downstream blood supply and reduce the risk during the operation. Moreover, by providing the through holes 221 on the connecting portion 22, blood can flow downstream through the through holes 221, reducing the impact of the blood flow on the implant 800, thereby increasing the positional stability of the implant 800 during the operation and increasing the consistency between the position during the positioning of the implant 800 and the position after the implantation is completed, thus improving the accuracy of the implantation position of the implant 800. In this embodiment, the through holes 221 can be circular, rectangular or other shapes.

[0059] Please refer to Figure 4A and Figure 4B , the binding structure 20 further includes a mounting portion 23. The mounting portion 23 extends along the length direction of the operating rod 11, and the mounting portion 23 is fixedly connected to the outer surface of the operating rod 11. The connecting portion 22 is fixedly connected to the mounting portion 23. The connecting portion 22 is connected to the operating rod 11 through the mounting portion 23, which can increase the contact area with the operating rod 11 and make the connection between the binding structure 20 and the operating rod 11 more reliable. The connection method of the mounting portion 23 and the operating rod 11 in this embodiment includes but is not limited to welding, glue bonding, etc.

[0060] In one embodiment, the binding portion 21, the connecting portion 22, and the mounting portion 23 are an integral structure. For example, the binding structure 20 is made of a tubular flexible polymer thermoplastic material. During manufacturing, the axial section corresponding to the mounting portion 23 can be heat-shrunk to match the size of the operating rod 11. Through holes 221 are provided on the axial section corresponding to the connecting portion 22, and the methods of providing the through holes 221 include but are not limited to cutting, laser cutting, etc. In another embodiment, the binding portion 21, the connecting portion 22, and the mounting portion 23 are a split structure. For example, the binding portion 21 and the mounting portion 23 are tubular structures, and the connecting portion 22 includes a plurality of connecting wires or connecting strips 222. Each connecting wire or connecting strip 222 is connected to both the binding portion 21 and the mounting portion 23. The connecting wires or connecting strips 222 are arranged at intervals in the circumferential direction and form through holes 221.

[0061] It should be noted that the cross-section corresponding to the above-mentioned cylinder is not necessarily limited to a circle. The cylinder only means having a circumferentially continuous side wall, and the circumferentially continuous side wall is not limited to a completely sealed side wall. The circumferentially continuous side wall includes the case where pores are formed on the side wall. For example, the shape of a braided network tube also belongs to the cylinder. The shape of the binding part 21 in this embodiment can be a hollow cylindrical shape, a hollow frustum shape, a hollow quadrangular prism shape, etc.

[0062] The process of loading the implant 800 and the process of releasing the implant 800 will be described in detail below with reference to the accompanying drawings, as follows:

[0063] The process for the operator to load the implant 800 into the transporter 100 is as follows:

[0064] Please refer to Figure 5 , operate the loading sheath 31 to move proximally relative to the operating rod 11 so that there is an axial gap sufficient to accommodate the implant 800 between the distal end of the loading sheath 31 and the proximal end of the binding part 21, that is, the loading section 111 is exposed. Then the implant 800 is sleeved on the operating rod 11 and located within this axial gap.

[0065] Please refer to Figure 6 , after compressing a part of the proximal end of the implant 800, then operate the loading sheath 31 to move distally to load a part of the proximal end of the implant 800 into the loading sheath 31 and maintain radial compression of the implant 800 through the loading sheath 31.

[0066] Please refer to Figure 7 , operate the operating rod 11 to move proximally relative to the loading sheath 31 and sleeve the binding part 21 on the distal end of the implant 800. The binding part 21 can radially restrain the distal end of the implant 800.

[0067] Please refer to Figure 8 , operate the loading sheath 31 to move distally relative to the operating rod 11, load the implant 800 and the binding structure 20 into the loading sheath 31, and make the distal end of the loading sheath 31 abut against the end head 41 to close the distal opening of the loading sheath 31, so as to seal the implant 800 in the loading sheath 31.

[0068] Of course, the method of loading the implant 800 into the transporter 100 can also be: first bind the distal end of the implant 800 to the binding structure 20, and then move the loading sheath 31 distally to radially compress both the implant 800 and the binding structure 20 in the inner cavity of the loading sheath 31.

[0069] Regarding the process of delivering the implant 800 to the target site through the transporter 100 and then releasing the implant 800, taking the implantation of the implant 800 into the aortic arch as an example for description.

[0070] Please refer to Figure 9 After a guide wire 900 is inserted into a blood vessel, a delivery device 100 is then delivered along the guide wire 900 to the lesion site of the blood vessel.

[0071] Please refer to Figure 10 As shown in FIG. Figure 10 , the operating sheath 31 is moved proximally relative to the operating rod 11 to release a portion of the implant 800 covered by the constrained portion 21 and a portion of the middle part. The proximal end of the implant 800 remains radially constrained in the operating sheath 31. The released portion of the implant 800 self-expands, and the portion of the implant 800 sleeved by the constrained portion 21 is constrained by the constrained portion 21. In this state, the radial dimension of the portion of the implant 800 constrained by the constrained portion 21 is greater than the outer diameter of the operating sheath 31, so that the radial dimension of the portion of the implant 800 constrained by the constrained portion 21 is closer to the dimension in the implanted state, that is, the radial dimension of the radially constrained portion of the implant 800 in this state is closer to the dimension of the implant 800 in the implanted state than the radial dimension of the implant 800 in the loaded state. The positioning of the implant 800 is more accurate in this state. Moreover, in this state, since the implant 800 has not adhered to the blood vessel wall, the position of the implant 800 can still be adjusted to meet the requirements.

[0072] Please refer to Figure 11 As shown in FIG. Figure 11 , after the positioning of the implant 800 is completed, the operating sheath 31 is continuously moved proximally relative to the operating rod 11 to release the proximal portion of the implant 800 that still lies in the inner cavity of the operating sheath 31.

[0073] Please refer to Figure 12 As shown in FIG. Figure 12 , by operating the operating rod 11 to rotate, the constrained portion 21 is separated from the implant 800, thereby releasing the semi-release constraint on the distal end of the implant 800. During the process of rotating the operating rod 11 to release the semi-release constraint of the constrained portion 21 on the implant 800, there is no need to axially move the operating rod 11, thus avoiding the puncture of the blood vessel wall by the operating rod 11.

[0074] Please refer to Figure 13 As shown in FIG. Figure 13 , the operating sheath 31 is moved distally relative to the operating rod 11. Since the constraint structure 20 is flexible, the operating sheath 31 can squeeze the constraint structure 20 and re-receive the constraint structure 20 into its inner cavity. After the constraint structure 20 is received into the operating sheath 31, the operating sheath 31 is abutted against the end head 41 to seal the distal end of the operating sheath 31, and then the delivery device 100 is withdrawn from the body to complete the implantation of the implant 800.

[0075] Second Embodiment

[0076] The difference between this embodiment and the first embodiment is that when the loading sheath 31 moves to expose a part of the restraining portion 21 and the implant 800, the exposed part of the implant 800 expands radially by itself, and the distal end of the implant 800 remains in a state of being restrained by the restraining portion 21. In this state, the diameter range of the restraining portion 21 sleeved on the distal end of the implant 800 is 50% to 75% of the diameter of the implant 800 in its natural state. Correspondingly, the through hole 221 is large enough to facilitate the implantation of the branch stent from the through hole 221. Moreover, during the process of implanting the branch stent, since the through hole 221 is large enough, it is beneficial to maintain smooth blood flow and improve the safety of the operation.

[0077] The third embodiment

[0078] Please refer to Figures 14A to 14C , the difference between this embodiment and the above embodiments is that the restraining portion 51 in this embodiment has shape memory characteristics. The restraining portion 51 is in a cylindrical shape, and the maximum radial dimension of the restraining portion 51 in its natural state is smaller than the inner diameter of the loading sheath 31. During the process of releasing the implant 800, when the loading sheath 31 moves to expose the restraining portion 51 and a part of the implant 800, the radial restraint on the restraining portion 51 disappears, the exposed part of the implant 800 expands radially by itself and radially expands the restraining portion 51, and the distal end of the implant 800 still remains in a state of being restrained by the restraining portion 51. In this state, the radial dimension of the restraining portion 51 is larger than its radial dimension in the natural state. When the restraining portion 51 is separated from the implant 800, after the restraining portion 51 loses the radial expansion effect of the implant 800, the restraining portion 51 automatically shrinks to its natural state without external force. In the natural state, the maximum radial dimension of the restraining portion 51 is smaller than the inner diameter of the loading sheath 31, which can improve the convenience of inserting the restraining portion 51 into the loading sheath 31, thereby saving the operation time and reducing the operation risk.

[0079] Specifically, please refer to Figure 14B and Figure 14C , the restraining portion 51 of the restraining structure 50 in this embodiment includes a cylindrical mesh structure 511 woven from a wire material with elasticity or shape memory, so that the restraining portion 51 has shape memory characteristics, and thus can automatically shrink to the size in the natural state when the restraining portion 51 is not under the radial expansion effect of the implant 800, and this size is smaller than the inner diameter of the loading sheath 31, thereby improving the convenience of inserting the restraining portion 51 into the loading sheath 31.

[0080] Please refer to again Figure 14A, in this embodiment, the binding part 51 further includes a covering part 512 made of a flexible material, so that the covering part 512 has flexibility. The covering part 512 is disposed on the outer surface of the cylindrical mesh structure 511. After the binding part 51 is separated from the distal end of the implant 800, the cylindrical mesh structure 511 contracts and deforms under the action of its own shape memory. Since the covering part 512 has flexibility, the covering part 512 can automatically contract and deform under the driving action of the cylindrical mesh structure 511, so that the maximum radial dimension of the binding part 51 is smaller than the inner diameter of the loading sheath 31, thereby improving the convenience of reinserting the binding part 51 into the loading sheath 31. In addition, since the covering part 512 has lubricity, the frictional resistance between the outer surface of the binding part 51 and the loading sheath 31 can be reduced, thereby reducing the release resistance. The material of the covering part 512 can be at least one of polytetrafluoroethylene (PTFE), polyurethane (PU), and polyester. In other embodiments, the covering part 512 of the binding part 51 can be omitted. After the covering part 512 is omitted, when the binding part 51 is not subjected to the radial expansion action of the implant 800, it automatically contracts to the size in the natural state, and this size is smaller than the inner diameter of the loading sheath 31, thereby improving the convenience of inserting the binding part 51 into the loading sheath 31.

[0081] The connecting part 52 in this embodiment includes a plurality of connecting wires 521. One end of each connecting wire 521 is connected to the binding part 51, and the other end is directly connected to the operating rod 11, or the other end of each connecting wire 521 is connected to the mounting part 53, so as to be connected to the operating rod 11 through the mounting part 53. Through holes 522 are formed between the connected connecting wires 521.

[0082] Fourth Embodiment

[0083] Please refer to Figure 15 , the difference between this embodiment and the third embodiment lies in the structure of the binding part 61 of the binding structure 60.

[0084] Specifically, please refer to Figure 15, the binding part 61 includes at least one corrugated ring 611. Each corrugated ring 611 is made of a material with elasticity or shape memory and has shape memory. The maximum radial dimension of each corrugated ring 611 when not under external force is smaller than the inner diameter of the loading sheath 31. When the loading sheath 31 moves along the operating rod 11 to expose the implant 800 and the binding part 61, the exposed part of the implant 800 expands radially by itself. The distal end of the implant 800 remains in a state of being bound by the binding part 61, and a part of the proximal end of the implant 800 is still radially bound by the loading sheath 31. In this state, the radial dimension of the part of the implant 800 radially constrained by the binding part 61 is larger than the outer diameter of the loading sheath 31. When the binding part 61 is separated from the implant 800, the binding part 61 automatically contracts to the size in its natural state, thereby improving the convenience of the binding part 61 being received into the loading sheath 31.

[0085] In one embodiment, in the semi-released binding state, each corrugated ring 611 can expand under the action of the self-expansion force of the implant 800. The range of the diameter of each expanded corrugated ring 611 is 30% to 75% of the diameter of the implant 800 when in the natural state, so that the radial dimension of the part of the implant 800 radially bound by the binding part 61 is smaller than the radial dimension of the implant 800 in the implanted state.

[0086] In one embodiment, the binding part 61 further includes a covering 612, and the covering 612 is connected to the connecting part 62. The covering 612 has flexibility and can expand and contract correspondingly as the corrugated ring 611 expands and contracts. The covering 612 has lubricity. The covering 612 is sleeved outside all the corrugated rings 611 and is connected to the outer surfaces of all the corrugated rings 611. When the loading sheath 31 moves proximally relative to the binding part 61 to release the part of the implant 800 sleeved by the binding part 61, the covering 612 provides lubricity, thereby reducing the release resistance. The material of the covering 612 can be at least one of polytetrafluoroethylene (PTFE), polyurethane (PU), and polyester. In other embodiments, the covering 612 of the binding part 61 can be omitted. After omitting the covering 612, the corrugated ring 611 at the distalmost end of the binding part 61 is connected to the connecting part 62.

[0087] In one embodiment, the number of corrugated rings 611 is multiple, and any two adjacent corrugated rings 611 are connected. For example, any two adjacent corrugated rings 611 are connected by an interlocking method or connected by other connecting pieces.

[0088] In one embodiment, a plurality of corrugated loops 611 are arranged at axial intervals, which can increase the flexibility of the binding portion 61, so as to be able to adapt to the curved lumen shape. Adjacent corrugated loops 611 are connected by a connector, and the elongation rate of the connector does not exceed 100%. When the operating rod 11 is operated to move the binding portion 61 distally relative to the implant 800 to separate from the implant 800, the length of the binding portion 61 stretched during this process is restricted, thereby shortening the time required for the binding portion 61 to be completely separated from the implant 800, and thus saving the operation time.

[0089] The test method for the above elongation rate can be measured according to the following method. Cut the connector into a specimen with a length not exceeding L1 and a width equal to D1. Fix the specimen on the fixture of the tensile machine, and the distance between the two fixtures is L2, where L2 < L1. Slowly stretch the connector until the sample breaks, and record the maximum force F during this process and the stretching length L3 of the connector at the maximum force. Then the elongation rate = (L3 - L2) / L2 * 100%.

[0090] The technical features of the above-described embodiments can be combined arbitrarily. For the sake of brevity of description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered to be within the scope described in this specification.

[0091] The above-disclosed are only the preferred embodiments of the present invention. Of course, the scope of the rights of the present invention cannot be limited thereby. Therefore, equivalent changes made according to the claims of the present invention still fall within the scope covered by the present invention.

Claims

1. A conveyor for conveying a self-expanding implant, characterized in that, it includes: an operating rod; a restraint structure including a restraint portion sleeved outside the operating rod and connected to the operating rod; a loading sheath movably sleeved on the operating rod; In the loading state, the operating rod is used to carry the implant, the restraint portion is used to sleeve the distal end of the implant, and both the implant and the restraint portion are located in the inner cavity of the loading sheath; when the loading sheath moves along the operating rod to expose the implant and the restraint portion, the distal end of the implant is radially restrained by the restraint portion and is in an incompletely released state, and the radial dimension of the portion of the implant radially restrained by the restraint portion is greater than the outer diameter of the loading sheath.

2. The conveyor according to claim 1, characterized in that, the restraint structure further includes a connecting portion, one end of the connecting portion is connected to the operating rod, the other end is connected to the restraint portion, and the connecting portion has flexibility.

3. The conveyor according to claim 2, characterized in that, a plurality of through holes are provided on the connecting portion, and the through holes communicate with the inner cavity of the restraint portion.

4. The conveyor according to claim 2 or 3, characterized in that, the restraint structure further includes a mounting portion, the mounting portion is fixedly connected to the end of the connecting portion away from the restraint portion, and the mounting portion extends along the length direction of the operating rod, and the mounting portion is fixedly connected to the outer surface of the operating rod.

5. The conveyor according to claim 1, characterized in that, the restraint portion is a flexible cylindrical structure.

6. The conveyor according to claim 1, characterized in that, the restraint portion is made of a shape memory material, the restraint portion is cylindrical, and the maximum radial dimension of the restraint portion in the natural state is smaller than the inner diameter of the loading sheath; when the loading sheath moves along the operating rod to expose the implant and the restraint portion, the radial dimension of the restraint portion is greater than its radial dimension in the natural state.

7. The conveyor according to claim 6, characterized in that, the restraint portion is a cylindrical mesh structure woven by a wire material with elasticity or shape memory; or, the restraint portion includes at least one corrugated ring made of a material with elasticity or shape memory.

8. The conveyor according to claim 7, characterized in that, the restraint portion further includes a flexible covering member, and the covering member is arranged on the outer surface of the cylindrical mesh structure; or, the covering member is arranged on the outer surface of the corrugated ring.

9. The conveyor according to claim 8, characterized in that, the material of the covering member has lubricity.

10. The conveyor according to claim 7, characterized in that, the number of the corrugated rings is multiple, and the multiple corrugated rings are arranged at intervals along the axial direction, and adjacent two corrugated rings are connected by a connecting object, and the elongation rate of the connecting object does not exceed 100%.

11. A conveying system, characterized in that, Comprising an implant and the delivery device according to any one of claims 1-10, in the loaded state, the implant is sleeved on the operating rod, the restraining portion is sleeved on the distal end of the implant, and both the implant and the restraining portion are located in the inner cavity of the loading sheath; when the loading sheath moves along the operating rod to expose the implant and the restraining portion, the distal end of the implant is radially restrained by the restraining portion and is in an incompletely released state, and the radial dimension of the portion of the implant radially restrained by the restraining portion is greater than the outer diameter of the loading sheath.

12. The delivery system according to claim 11, wherein, when the loading sheath moves along the operating rod to expose the implant and the restraining portion, and the distal end of the implant is radially restrained by the restraining portion and is in an incompletely released state, the diameter of the restraining portion is 30% to 75% of the diameter of the implant in the natural state.

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