Wavelength precise control device and photodynamic therapeutic instrument

Abstract

The invention relates to the technical field of medicine, and discloses a wavelength precise control device and a photodynamic therapeutic apparatus, the wavelength precise control device comprises a therapeutic apparatus body, the outer side of the therapeutic apparatus body is provided with a therapeutic optical device, and the therapeutic optical device is connected with the therapeutic apparatus body; the therapeutic apparatus body comprises a display, the bottom of the display is fixedly connected with a case, the left side of the case is fixedly connected with an optical fiber adapter, the outer side of the optical fiber adapter is fixedly connected with an optical fiber for treatment, the outer side of the case is provided with an upper computer, the upper computer is electrically connected with a TEC module, and the TEC module is electrically connected with the computer. The upper computer is electrically connected with a driving module, the upper computer is electrically connected with a laser module, the TEC module is electrically connected with the driving module, the driving module is electrically connected with the laser module, and the upper computer is electrically connected with a wavelength detection device. According to the wavelength accurate control device and the photodynamic therapeutic instrument, the temperature of the laser is controlled to change the wavelength, and one device has two wavelengths.

Description

Technical Field

[0001] The present invention relates to the field of medical technology, and particularly to a device for precise wavelength control and a photodynamic therapy instrument. Background Art

[0002] Photodynamic therapy for cancer mainly includes: early tumors can be cured, and palliative treatment can be carried out for advanced tumors. As long as the optical fiber can reach, treatment can be performed. In Western countries, medical staff also use photodynamic therapy for antiviral and antibacterial treatments. The advantage of photodynamic therapy is selective treatment of tumors, which has the functions of beauty and organ function preservation, which cannot be compared with other minimally invasive treatments.

[0003] Domestic photosensitizers used in clinical applications include Xipofen and ALA, etc. Laser optical fibers include cylindrical optical fibers, microlens optical fibers, and flat-cut optical fibers, etc. The absorption wavelength of Xipofen commonly used is 630 nm, and the absorption wavelength of ALA is 635 nm. Currently, domestic photodynamic therapy instruments are usually single-wavelength therapy instruments. The therapy instrument using a wavelength of 630 nm uses Xipofen as the drug, and the therapy instrument using a wavelength of 635 nm uses ALA as the drug. Therefore, the drug use of conventional therapy instruments is limited, and the uses for treating diseases are limited.

[0004] Therefore, there is an urgent need for a device for precise wavelength control and a photodynamic therapy instrument. Summary of the Invention

[0005] The purpose of the present invention is to provide a device for precise wavelength control and a photodynamic therapy instrument to solve the problems raised in the above background art.

[0006] To solve the above technical problems, the present invention provides the following technical solutions: A device for precise wavelength control and a photodynamic therapy instrument, including a therapy instrument body, a treatment optical device is arranged on the outside of the therapy instrument body, and the treatment optical device is connected to the therapy instrument body; The therapy instrument body includes a display, a chassis is fixedly connected to the bottom of the display, an optical fiber adapter is fixedly connected to the left side of the chassis, a treatment optical fiber is fixedly connected to the outside of the optical fiber adapter, a host computer is arranged on the outside of the chassis, the host computer is electrically connected to a TEC module, the host computer is electrically connected to a driving module, the host computer is electrically connected to a laser module, the TEC module is electrically connected to the driving module, the driving module is electrically connected to the laser module, and the host computer is electrically connected to a wavelength detection device; The treatment optical device includes a flat-cut optical fiber, the flat-cut optical fiber is fixedly connected to the treatment optical fiber, a collimating lens is arranged on the outside of the flat-cut optical fiber, a microlens array is arranged on the outside of the collimating lens, a tapered optical fiber for in vivo use is arranged on the outside of the microlens array, and a spherical optical fiber for in vivo use is arranged on the outside of the microlens array.

[0007] Preferably, a panel is provided on the front of the display, and the panel displays laser temperature, laser power, laser power density, and real-time wavelength.

[0008] Preferably, the wavelength detection device comprises a first laser, a first wind and light sheet is arranged outside the first laser, a prism is arranged outside the first wind and light sheet, and a first wavelength detection head is arranged outside the prism.

[0009] Preferably, the laser module is electrically connected to a combiner optical fiber, the combiner optical fiber is electrically connected to an adapter panel, and the adapter panel is fixedly connected to the optical fiber adapter.

[0010] Preferably, the host computer is electrically connected to a power feedback device, and the host computer is electrically connected to a wavelength feedback device.

[0011] Preferably, the wavelength feedback device is electrically connected to the adapter panel, and the power feedback device is electrically connected to the adapter panel.

[0012] Preferably, the display is electrically connected to a host computer, and the display is electrically connected to a transfer panel.

[0013] Preferably, a foot pedal is fixedly connected to the back of the chassis, and the foot pedal is electrically connected to the upper machine.

[0014] Preferably, a wavelength detection alternative device is also included, which includes a second laser, a second beam splitter is arranged outside the second laser, a grating is arranged outside the second beam splitter, and a second wavelength detection head is arranged outside the grating.

[0015] Compared with the prior art, the beneficial effects achieved by the present invention are: First, in the present invention, the laser module uses a semiconductor laser. Through fiber coupling, the integration of multiple laser diodes is achieved, supporting continuous adjustment of power from 0 to 2W, with a power density range of 50 - 300 mw / cm². The TEC module uses the model TCM-X107. The drive module powers the laser module. The beam combiner fiber is composed of multiple 100 / 200-micron fibers fused into a 400-micron fiber. The loose end is the fiber input end, connected to the laser module. The combined beam end is the beam output end, connected to a fiber optic adapter, and through the adapter, it is connected to the treatment fiber. The treatment fiber is of medical grade, with a core diameter of 400 microns, supporting flat-cut fiber. The foot switch is used to control the laser output. The display panel displays information such as laser temperature, laser power, power density, and wavelength in real time. The light emitted by the first laser passes through the first beam splitter. The splitting ratio of the first beam splitter is customized according to a certain transmittance. This wavelength detection device is customized with a transmittance of 5%:95%. 5% of the laser enters the prism, and 95% is emitted as the treatment light. Due to dispersion, the prism can separate different wavelengths. Different wavelengths reach different positions of the first wavelength detection head, and each position corresponds to a corresponding photodiode detection head. The device's background is built-in with a signal processing system. The signal processing system receives the electrical signals transmitted by the detectors and performs processing such as amplification, filtering, and digitization. The processed signals are analyzed in real time by the signal processing system and fed back to the host computer. The host computer uses a computer. There is an existing patent using this host computer, with the patent name: A nevus flammeus treatment device and its operation method, and the patent number: 202410286348.5. By sending instructions to the laser module in real time through the host computer, the power of the first laser can be controlled. Moreover, there is a power tester and a power feedback device inside the treatment device, which can monitor the power in real time and adjust the current in real time according to the instructions to maintain a stable output of the power. The wavelength of the light emitted by the first laser is monitored in real time through the wavelength feedback device and fed back to the host computer. The host computer calculates the control value through the PID algorithm based on the difference between the current wavelength value and the set value, calculates the output control amount according to the difference between the set wavelength and the actual wavelength to control the output of the TEC module to adjust the temperature of the first laser, thereby achieving precise control of the wavelength. It realizes a stable output of the power of the first laser and also realizes a change in wavelength. The wavelength control accuracy of this device can reach 0.2 nm. According to experience, for every 1-degree increase in temperature, the wavelength increases by approximately 0.3 nm. The wavelength of the 635-nm LD is 635 nm at room temperature of 25 degrees. When the temperature is controlled at approximately 10 degrees, the wavelength can reach 630 nm, thereby achieving precise control of the wavelength, enabling the wavelength to be stabilized near the set value and being able to precisely control the wavelength to switch between 630 nm and 635 nm, solving the problem that the treatment device has only a single wavelength.

[0016] Second, when the present invention is used for the treatment of superficial tumors, the target wavelength of 635 nm is set on the device interface. At this time, the wavelength is controlled to 635 nm through the wavelength feedback device and the temperature control device. A fiber optic device for superficial treatment is connected to the fiber optic interface of the device. This device uses a flat-cut fiber, and through optical shaping, the power density and spot uniformity at the target distance can be achieved. The common power density range is 50 - 300 mw / cm2, and the conventional treatment time is 10 - 30 min, which can be set according to the size and degree of the diseased area. The light emitted from the fiber undergoes beam shaping and homogenization through a microlens array. The microlens array can achieve a spot uniformity of more than 95%. The microlens array can output square spots, rectangular spots, and dot matrix spots. When the size of the microlens is 1.25 * 1.25 mm and the radius of curvature is 2.433 mm, a square spot with a side length of 6 cm at a working distance of 10 cm can be achieved. For nevus flammeus on the human epidermis, especially on the face, according to the size of the patient, the spot size and power density can be adjusted to treat more than 90% of epidermal diseases. When used for the treatment of internal tumors, the wavelength is controlled to 630 nm. The device is replaced with a tapered fiber or a spherical fiber through fiber optic docking, which can more easily enter the human body cavity. And this type of fiber has a larger divergence angle and better uniformity compared to the flat-cut fiber. The conventional divergence angle can reach more than 60 degrees, and the uniformity is more than 80%, which has a better treatment effect on internal tumors. This method has low cost and simple customization, and can also achieve a spot uniformity of more than 90%. Compared with a spectrometer, it has a lower cost, but can effectively achieve precise detection and control of the wavelength.

[0017] Third, in the present invention, the wavelength detection device in the original device is replaced by a wavelength detection alternative device. The light emitted from the second laser passes through the second beam splitter. The splitting ratio of the second beam splitter can be customized according to a certain transmittance. This wavelength detection alternative device is customized according to a transmittance of 5%:95%. 5% of the laser enters the grating, and 95% is emitted as the treatment light. The grating can separate different wavelengths through grating diffraction. Different wavelengths reach different positions of the second wavelength detection head, and each position corresponds to a corresponding photodiode detection head. This photodynamic therapy device has an optical treatment device with two treatment methods. A prism with a lower customization cost can be selected, which has applications in spectral analysis, laser beam adjustment, etc. Or a grating with a higher customization cost and more complex processes can be selected for detection. It has a higher spectral resolution and more precise wavelength control, and can switch more precisely between two wavelengths. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 is an overall three-dimensional schematic diagram of the structure of the present invention; Figure 2 is a partial schematic diagram of the optical treatment device of the structure of the present invention; Figure 3It is a partial schematic diagram of the optical device for structural treatment of the present invention; Figure 4 A schematic diagram of a structure display of the present invention; Figure 5 This is a schematic diagram of the structural therapeutic device of the present invention; Figure 6 It is a schematic diagram of the structural wavelength detection device of the present invention; Figure 7 This is a schematic diagram of the structural wavelength detection alternative device of the present invention.

[0019] Legend: 1. Therapeutic instrument body; 11. Display; 12. Chassis; 13. Optical fiber adapter; 14. Optical fiber for treatment; 15. Foot pedal; 2. Optical devices for treatment; 21. Cut optical fibers; 22. Collimating lenses; 23. Microlens arrays; 24. Conical optical fibers for in vivo use; 25. Spherical optical fibers for in vivo use.

[0020] 31. Host computer; 32. TEC module; 33. Drive module; 34. Laser module; 35. Combiner optical fiber; 36. Power feedback device; 37. Adapter panel; 38. Wavelength feedback device; 39. Wavelength detection device; 51. a first laser; 52. a first beam splitter; 53. a prism; 54. a first wavelength detector; 6. Wavelength detection alternative device; 61. Second laser; 62. Second beam splitter; 63. Grating; 64. Second wavelength detection head. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0022] Embodiment 1 like Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7 As shown, the present invention provides a technical solution: a device for precise wavelength control and a photodynamic therapy device, comprising a therapy device body 1, a therapeutic optical device 2 is arranged outside the therapy device body 1, and the therapeutic optical device 2 is connected to the therapy device body 1; The therapeutic apparatus body 1 includes a display 11, the bottom of the display 11 is fixedly connected to a chassis 12, the left side of the chassis 13 is fixedly connected to an optical fiber adapter 13, the outer side of the optical fiber adapter 13 is fixedly connected to a therapeutic optical fiber 14, a host computer 31 is arranged on the outer side of the chassis 12, the host computer 31 is electrically connected to a TEC module 32, the host computer 31 is electrically connected to a drive module 33, the host computer 31 is electrically connected to a laser module 34, the TEC module 32 is electrically connected to the drive module 33, the drive module 33 is electrically connected to the laser module 34, and the host computer 31 is electrically connected to a wavelength detection device 39; The therapeutic optical device 2 includes a cleaved optical fiber 21, which is fixedly connected to the therapeutic optical fiber 14. A collimating lens 22 is arranged on the outside of the cleaved optical fiber 21, a microlens array 23 is arranged on the outside of the collimating lens 22, a conical optical fiber 24 for in vivo use is arranged on the outside of the microlens array 23, and a spherical optical fiber 25 for in vivo use is arranged on the outside of the microlens array 23.

[0023] A panel is provided on the front of the display 11, and the panel displays the laser temperature, laser power, laser power density, and real-time wavelength.

[0024] The wavelength detection device 39 includes a first laser 51 , a first wind and light panel 52 is disposed outside the first laser 51 , a prism 53 is disposed outside the first wind and light panel 52 , and a first wavelength detection head 54 is disposed outside the prism 53 .

[0025] The laser module 34 is electrically connected to the combiner optical fiber 35 , the combiner optical fiber 35 is electrically connected to the adapter panel 37 , and the adapter panel 37 is fixedly connected to the optical fiber adapter 13 .

[0026] The host computer 31 is electrically connected to a power feedback device 36 , and the host computer 31 is electrically connected to a wavelength feedback device 38 .

[0027] The wavelength feedback device 38 is electrically connected to the adapter panel 37 , and the power feedback device 36 is electrically connected to the adapter panel 37 .

[0028] The display 11 is electrically connected to the host computer 31 , and the display 11 is electrically connected to the adapter panel 37 .

[0029] A pedal 15 is fixedly connected to the back of the chassis 12 , and the pedal 15 is electrically connected to the host computer 31 .

[0030] Through the above technical solutions, among which, the laser module 34 adopts a semiconductor laser, and through the fiber coupling method, the integration of multiple laser diodes is realized, supporting continuous adjustment of the power from 0 to 2W, with the power density range of 50 - 300 mw / cm². The TEC module 32 adopts the model TCM-X107. The drive module 33 supplies power to the laser module 34. The beam combiner fiber 35 is composed of multiple 100 / 200-micron fibers fused into a 400-micron fiber. The loose end is the fiber input end, connected to the laser module 34, and the combined end is the beam output end, connected to the fiber adapter 13. Through the adapter, it is connected to the treatment fiber 14. The treatment fiber 14 is of medical grade, with a core diameter of 400 microns, supporting the flat-cut fiber 21. The foot switch 15 is used to control the laser output. The display 11 panel displays information such as the laser temperature, laser power, power density, and wavelength in real time. The light emitted by the first laser 51 passes through the first beam splitter 52. The splitting ratio of the first beam splitter 52 is customized according to a certain transmittance. This wavelength detection device 39 is customized according to a transmittance of 5%:95%. 5% of the laser enters the prism 53, and 95% is emitted as the treatment light. Due to the dispersion of the prism 53, different wavelengths can be separated. Different wavelengths reach different positions of the first wavelength detection head 54, and each position corresponds to a corresponding photodiode detection head. There is a signal processing system built into the device background. The signal processing system receives the electrical signals transmitted by the detectors and performs processing such as amplification, filtering, and digitization. The processed signals are analyzed in real time by the signal processing system and fed back to the host computer 31. The host computer 31 uses a computer. There is an existing patent using this host computer 31, with the patent name: A nevus flammeus treatment instrument and its operation method, and the patent number: 202410286348.5. By sending instructions to the laser module 34 in real time through the host computer 31, the power of the first laser 51 can be controlled. Moreover, there is a power tester and a power feedback device 36 inside the treatment instrument, which can monitor the power in real time and adjust the current in real time according to the instructions to maintain a stable output of the power. The wavelength feedback device 38 monitors the output wavelength of the first laser 51 in real time and feeds it back to the host computer 31. The host computer 31 calculates the control value through the PID algorithm based on the current wavelength value and the set value, and calculates the output control amount according to the difference between the set wavelength and the actual wavelength to control the output of the TEC module 32 to adjust the temperature of the first laser 51, thereby achieving precise control of the wavelength. It realizes a stable output of the power of the first laser 51 and also realizes the change of the wavelength. The wavelength control accuracy of this device can reach 0.2 nm. According to experience, for every 1-degree increase in temperature, the wavelength increases by approximately 0.3 nm. The wavelength of the 635-nm LD is 635 nm at room temperature of 25 degrees. When the temperature is controlled at about 10 degrees, the wavelength can reach 630 nm, thus achieving precise control of the wavelength, enabling the wavelength to be stabilized near the set value, and being able to precisely control the wavelength to switch between 630 nm and 635 nm, solving the problem that the treatment instrument has only a single wavelength.When used for the treatment of superficial tumors, set the target wavelength to 635 nm on the device interface. At this time, the wavelength is controlled to 635 nm through the wavelength feedback device 38 and the temperature control device. Connect the optical fiber device 14 for superficial treatment at the fiber optic interface of the device. This device uses a flat-cut optical fiber 21, and through optical shaping, the power density and spot uniformity at the target distance can be achieved. The common power density range is 50 - 300 mw / cm2, and the conventional treatment time is 10 - 30 min, which can be set according to the size and degree of the diseased area. The light output from the optical fiber is beam-shaped and homogenized by the microlens array 23. The microlens array 23 can achieve a spot uniformity of more than 95%. The microlens array 23 can output square spots, rectangular spots, and dot matrix spots. When the size of the microlens is 1.25 * 1.25 mm and the radius of curvature is 2.433 mm, a square spot with a side length of 6 cm at a working distance of 10 cm can be achieved. For nevus flammeus on the human epidermis, especially on the face, according to the size of the patient, the spot size and power density can be adjusted to treat more than 90% of epidermal diseases. When used for the treatment of internal tumors, the wavelength is controlled to 630 nm. The device is replaced with a tapered optical fiber 24 or a spherical optical fiber 25 through fiber optic docking, which can more easily enter the human body cavity. And this type of optical fiber has a larger divergence angle and better uniformity compared to the flat-cut optical fiber 21. The conventional divergence angle can achieve more than 60 degrees, and the uniformity is more than 80%, which has a better treatment effect on internal tumors. This method has low cost and simple customization, and can also achieve a spot uniformity of more than 90%. Compared with a spectrometer, it has a low cost but can effectively achieve precise detection and control of the wavelength.

[0031] Embodiment 2 As Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 、 Figure 5 、 Figure 6 and Figure 7 As shown in

[0032] Through the above technical solution, the wavelength detection substitution device 6 replaces the wavelength detection device 39 in the original equipment. The light emitted by the second laser 61 passes through the second beam splitter 62. The splitting ratio of the second beam splitter 62 can be customized according to a certain transmittance. This wavelength detection substitution device 6 is customized according to a transmittance of 5%:95%. 5% of the laser enters the grating 63, and 95% is emitted as the treatment light. The grating 63 can separate different wavelengths through grating diffraction. Different wavelengths reach different positions of the second wavelength detection head 64, and each position corresponds to a corresponding photodiode detection head. This photodynamic therapy instrument has an optical treatment device with two treatment methods. The prism 53 with a lower customization cost can be selected, which has applications in spectral analysis, laser beam adjustment, etc. Or the grating 63 with a higher customization cost and more complex processes can be selected for detection. It has higher spectral resolution and more precise wavelength control, and can switch more accurately between two wavelengths.

[0033] During use, the laser module 34 uses a semiconductor laser. Through fiber coupling, the integration of multiple laser diodes is achieved, supporting continuous power adjustment from 0 to 2W, with a power density range of 50 - 300 mw / cm². The TEC module 32 uses the model TCM-X107. The drive module 33 supplies power to the laser module 34. The beam combiner fiber 35 is composed of a 400-micron fiber formed by fusing multiple 100 / 200-micron fibers. The loose end is the fiber input end, connected to the laser module 34, and the combined end is the beam output end, connected to the fiber adapter 13. Through the adapter, it is connected to the treatment fiber 14. The treatment fiber 14 is medical-grade, with a core diameter of 400 microns, supporting the flat-cut fiber 21. The foot switch 15 is used to control the laser output. The display 11 panel displays information such as the laser temperature, laser power, power density, and wavelength in real time. The light emitted by the first laser 51 passes through the first beam splitter 52. The splitting ratio of the first beam splitter 52 is customized according to a certain transmittance. This wavelength detection device 39 is customized with a transmittance of 5%:95%. 5% of the laser enters the prism 53, and 95% is emitted as the treatment light. Due to dispersion, the prism 53 can separate different wavelengths. Different wavelengths reach different positions of the first wavelength detection head 54, and each position corresponds to a corresponding photodiode detection head. There is a signal processing system built into the device background. The signal processing system receives the electrical signals transmitted by the detectors and performs processing such as amplification, filtering, and digitization. The processed signals are analyzed in real time by the signal processing system and fed back to the host computer 31. The host computer 31 uses a computer. The existing patent uses this host computer 31, with the patent name: A nevus flammeus treatment device and its operation method, and the patent number: 202410286348.5. By sending instructions to the laser module 34 in real time through the host computer 31, the power of the first laser 51 can be controlled. And there is a power tester and a power feedback device 36 inside the treatment device, which can monitor the power in real time and adjust the current in real time according to the instructions to maintain a stable power output. The wavelength feedback device 38 monitors the output wavelength of the first laser 51 in real time and feeds it back to the host computer 31. The host computer 31 calculates the control value through the PID algorithm based on the difference between the current wavelength value and the set value, calculates the output control amount according to the difference between the set wavelength and the actual wavelength to control the output of the TEC module 32 to adjust the temperature of the first laser 51, thereby achieving precise control of the wavelength. It realizes a stable output of the power of the first laser 51 and also realizes the change of the wavelength. The wavelength control accuracy of this device can reach 0.2 nm. According to experience, for every 1-degree increase in temperature, the wavelength increases by approximately 0.3 nm. The wavelength of the 635-nm LD is 635 nm at room temperature of 25 degrees. When the temperature is controlled at about 10 degrees, the wavelength can reach 630 nm, thus achieving precise control of the wavelength, enabling the wavelength to be stable near the set value, and being able to precisely control the wavelength to switch between 630 nm and 635 nm, solving the problem that the treatment device has only a single wavelength.When used for the treatment of superficial tumors, set the target wavelength to 635 nm on the device interface. At this time, the wavelength is controlled to 635 nm through the wavelength feedback device 38 and the temperature control device. Connect the optical fiber device for superficial treatment at the fiber optic interface of the device. This device uses a flat-cut optical fiber 21, and through optical shaping, the power density and spot uniformity at the target distance can be achieved. The common power density range is 50 - 300 mw / cm2, and the conventional treatment time is 10 - 30 min, which can be set according to the size and severity of the diseased area. The light emitted from the optical fiber is beam-shaped and homogenized by the microlens array 23. The microlens array 23 can achieve a spot uniformity of more than 95%. The microlens array 23 can output square spots, rectangular spots, and dot matrix spots. When the size of the microlens is 1.25 * 1.25 mm and the radius of curvature is 2.433 mm, a square spot with a side length of 6 cm at a working distance of 10 cm can be achieved. For nevus flammeus on the human epidermis, especially on the face, according to the size of the patient, the spot size and power density can be adjusted to treat more than 90% of epidermal diseases. When used for the treatment of internal tumors, the wavelength is controlled to 630 nm. The device is replaced with a tapered optical fiber 24 or a spherical optical fiber 25 through fiber optic docking, which can more easily enter the human body cavity. And this type of optical fiber has a larger divergence angle and better uniformity compared to the flat-cut optical fiber 21. The conventional divergence angle can reach more than 60 degrees, and the uniformity is more than 80%, which has a better treatment effect on internal tumors. This method has low cost and simple customization, and can also achieve a spot uniformity of more than 90%. Compared with a spectrometer, it has a lower cost, but can effectively achieve accurate detection and control of the wavelength. Replace the wavelength detection device 39 in the original device with the wavelength detection alternative device 6. The light emitted from the second laser 61 passes through the second beam splitter 62. The splitting ratio of the second beam splitter 62 can be customized according to a certain transmittance. This wavelength detection alternative device 6 is customized according to a transmittance of 5%:95%. 5% of the laser enters the grating 63, and 95% is emitted as the treatment light. The grating 63 can separate different wavelengths through grating diffraction. Different wavelengths reach different positions of the second wavelength detection head 64, and each position corresponds to a corresponding photodiode detection head. This photodynamic therapy device has an optical treatment device with two treatment methods. The prism 53 with lower customization cost can be selected for applications in spectral analysis, laser beam adjustment, etc. Or the grating 63 with higher customization cost and more complex processes can be selected for detection. It has higher spectral resolution and more precise wavelength control, and can switch more accurately between two wavelengths.

[0034] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principle and spirit. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A device for precise wavelength control and a photodynamic therapy device, comprising a therapy device body (1), characterized in that: A therapeutic optical device (2) is arranged outside the therapeutic device body (1), and the therapeutic optical device (2) is connected to the therapeutic device body (1); The therapeutic device body (1) comprises a display (11), the bottom of the display (11) is fixedly connected to a chassis (12), the left side of the chassis (13) is fixedly connected to an optical fiber adapter (13), the outer side of the optical fiber adapter (13) is fixedly connected to a therapeutic optical fiber (14), a host computer (31) is arranged on the outer side of the chassis (12), the host computer (31) is electrically connected to a TEC module (32), the host computer (31) is electrically connected to a drive module (33), the host computer (31) is electrically connected to a laser module (34), the TEC module (32) is electrically connected to the drive module (33), the drive module (33) is electrically connected to the laser module (34), and the host computer (31) is electrically connected to a wavelength detection device (39); The therapeutic optical device (2) comprises a cleaved optical fiber (21), the cleaved optical fiber (21) being fixedly connected to the therapeutic optical fiber (14), a collimating lens (22) being arranged outside the cleaved optical fiber (21), a microlens array (23) being arranged outside the collimating lens (22), an in vivo conical optical fiber (24) being arranged outside the microlens array (23), and an in vivo spherical optical fiber (25) being arranged outside the microlens array (23).

2. The device for precise wavelength control and photodynamic therapy apparatus according to claim 1, characterized in that: The display (11) has a panel on its front side, and the panel displays laser temperature, laser power, laser power density, and real-time wavelength.

3. The device for precise wavelength control and photodynamic therapy apparatus according to claim 1, characterized in that: The wavelength detection device (39) comprises a first laser (51), a first light-sensing plate (52) is arranged outside the first laser (51), a prism (53) is arranged outside the first light-sensing plate (52), and a first wavelength detection head (54) is arranged outside the prism (53).

4. The device for precise wavelength control and photodynamic therapy apparatus according to claim 1, characterized in that: The laser module (34) is electrically connected to a beam combiner optical fiber (35), the beam combiner optical fiber (35) is electrically connected to an adapter panel (37), and the adapter panel (37) is fixedly connected to the optical fiber adapter (13).

5. The device for precise wavelength control and photodynamic therapy apparatus according to claim 1, characterized in that: The host computer (31) is electrically connected to a power feedback device (36), and the host computer (31) is electrically connected to a wavelength feedback device (38).

6. The device for precise wavelength control and photodynamic therapy apparatus according to claim 1, characterized in that: The wavelength feedback device (38) is electrically connected to the adapter panel (37), and the power feedback device (36) is electrically connected to the adapter panel (37).

7. The device for precise wavelength control and photodynamic therapy apparatus according to claim 2, characterized in that: The display (11) is electrically connected to the host computer (31), and the display (11) is electrically connected to the adapter panel (37).

8. The device for precise wavelength control and photodynamic therapy apparatus according to claim 1, characterized in that: A foot pedal (15) is fixedly connected to the back of the chassis (12), and the foot pedal (15) is electrically connected to the host computer (31).

9. The device for precise wavelength control and photodynamic therapy apparatus according to claim 1, characterized in that: Also included is a wavelength detection replacement device, the wavelength detection replacement device comprising a second laser (61), a second beam splitter (62) being arranged outside the second laser (61), a grating (63) being arranged outside the second beam splitter (62), and a second wavelength detection head being arranged outside the grating (63).

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