Lactobacillus plantarum S8 and application thereof in mycotoxin degradation

Through Lactiplantibacillus plantarum S8 isolated from fermented dairy products, a variety of mycotoxin degradation problems were solved, and efficient degradation of ochratoxin A, zearalenone, aflatoxin B1 and vomiting toxin was achieved, and its safety and application potential in food and feed were demonstrated.

CN120060055APending Publication Date: 2025-05-30KUNMING UNIV OF SCI & TECH
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Patent Information

Application Number
CN202510279560.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-11
Publication Date
2025-05-30

AI Technical Summary

Technical Problem

The prior art is difficult to effectively degrade a variety of mycotoxins, especially ochratoxin A, zearalenone, aflatoxin B1 and vomiting toxins, making it difficult to control mycotoxin contamination in food and animal products, affecting human and animal health.

Method used

Lactipanitibacillus plantarum S8 was isolated from fermented dairy products, which has excellent degradation of multiple mycotoxins and ensures its viability in the gastrointestinal tract through its acid and bile salt resistance.

Benefits of technology

Strain S8 degrades 100%, 95.6%, 70.54%, and 55.8% of OTA, ZEN, AFB1, DON at 20μg/mL within 24 hours, and maintains a high survival rate under different pH and bile salt concentrations, ensuring its safety and application potential in food and feed.

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Abstract

The invention discloses a Lactobacillus plantarum S8, the preservation number of the Lactobacillus plantarum S8 in Guangdong Microbial Culture Collection Center is GDMCC NO: 65704, the strain is applied to degradation of ochratoxin A (OTA), zearalenone (ZEN), aflatoxin B1 (AFB1) and deoxynivalenol (DON), and the strain can be used for degrading ochratoxin A (OTA), zearalenone (ZEN), aflatoxin B1 (AFB1) and deoxynivalenol (DON). The results show that the strain S8 has excellent ochratoxin, aflatoxin, vomitoxin and zearalenone degradation capability, and can survive in an MRS culture medium with the pH value of 2-5 and an MRS culture medium containing ox bile salt, so that the strain is proved to have relatively strong gastrointestinal tract viability, and the strain has huge application potential in the aspects of drug, food and feed attenuation; the invention provides a new way for removing mycotoxin residues in medicines, foods and feeds, enriches a germplasm resource library of mycotoxin degrading bacteria, and has a better application prospect.
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Claims

1. A strain of Lactobacillus plantarum ( Lactiplantibacillus plantarum ) S8, its deposit number in Guangdong Provincial Microbiological Culture Collection Center is GDMCC NO: 65704.

2. The use of Lactobacillus plantarum S8 in degrading mycotoxins according to claim 1, characterized in that: The fungal toxins are one or more of ochratoxin A, zearalenone, aflatoxin B1, and vomitoxin.

Citation Information

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