Medicinal oil for traditional Chinese medicine acupuncture and moxibustion and preparation method thereof

Abstract

The invention discloses medicinal oil for traditional Chinese medicine acupuncture and moxibustion and a preparation method thereof. The invention belongs to the technical field of traditional Chinese medicines, and aims to improve the permeability and stability of medicinal oil and enhance the synergistic effect of the medicinal oil and acupuncture therapy by optimizing the formula design, thereby meeting the requirements of modern traditional Chinese medicine clinic on efficient and safe acupuncture medicinal oil. The medicinal oil for traditional Chinese medicine acupuncture and moxibustion and the preparation method thereof provided by the invention have remarkable technical advantages and application value, and the unique formula design and preparation process not only remarkably improve the permeability and stability of the medicinal oil, but also enhance the synergistic effect of the medicinal oil and acupuncture and moxibustion therapy; therefore, the requirements of modern traditional Chinese medicine clinic on efficient and safe acupuncture medicinal oil are met; meanwhile, the preparation method is easy to operate, does not need extra specific equipment, is suitable for batch industrial production, and has wide market prospects and popularization value.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine, and specifically refers to a medicinal oil for traditional Chinese medicine acupuncture and a preparation method thereof. Background Art

[0002] With the widespread application of traditional Chinese medicine acupuncture therapy, acupuncture oil, as an auxiliary treatment method, has played an important role in improving efficacy and relieving pain. However, the existing acupuncture oil still has some shortcomings in formula design, preparation process and indication range, which affects its clinical application effect and promotion value.

[0003] A kind of acupuncture medicated oil and its preparation method with publication number CN102579691B, the publication date is September 25, 2013. The patent is based on the optimization and improvement of the ancient Zhuang prescription, with cinnamon twig, agarwood, costusroot, safflower, angelica, Achyranthes bidentata, Chuanxiong, musk as raw materials, and is used to treat headache, cervical or lumbar vertebrae hyperplasia, knee joint synovitis, gout, rheumatoid arthritis and other diseases. However, in this technical solution, the formula ingredients of the medicated oil are relatively traditional, lacking further integration with the needs of modern medicine, such as less targeted applications for nervous system diseases or immune system diseases. In addition, the patent does not elaborate on the permeability and absorption efficiency of the medicated oil during acupuncture, which may lead to unstable efficacy and affect the overall treatment effect.

[0004] A Zhuang medicine moxibustion medicated oil and its preparation method with publication number CN115944698B, the publication date is September 29, 2023. This patent is prepared by combining multiple Chinese medicines such as frankincense, myrrh, Panax notoginseng, and Croton tiglium, and combined with vegetable oil. It is mainly used for the auxiliary treatment of diseases such as hemiplegia caused by stroke, amnesia, dementia, and rheumatic joint pain. However, in this technical solution, the formula of the medicated oil is relatively complex, and the addition ratio of some raw materials such as borneol and menthol is relatively small, which may make it difficult to give full play to its synergistic effect. At the same time, the patent does not explicitly mention the stability and shelf life of the medicated oil under different temperature conditions, which may affect its reliability and safety in actual use. In addition, the medicated oil mainly focuses on moxibustion applications, and its compatibility with acupuncture has not been fully verified.

[0005] In summary, the existing acupuncture oil still has certain deficiencies in terms of formula innovation, efficacy stability, preparation process optimization, and compatibility with acupuncture therapy. Therefore, the present invention provides a Chinese medicine acupuncture oil and a preparation method thereof, aiming to meet the needs of modern Chinese medicine clinics for efficient and safe acupuncture oil by optimizing the formula design, improving the permeability and stability of the oil, and enhancing its synergistic effect with acupuncture therapy. Summary of the invention

[0006] The purpose of the present invention is to provide a Chinese medicine acupuncture medicated oil and a preparation method thereof. The present invention aims to meet the needs of modern Chinese medicine clinics for efficient and safe acupuncture medicated oil by optimizing the formula design, improving the permeability and stability of the medicated oil, and enhancing the synergistic effect between the medicated oil and acupuncture therapy. The Chinese medicine acupuncture medicated oil and the preparation method thereof provided by the present invention have significant technical advantages and application value. The unique formula design and preparation process not only significantly improve the permeability and stability of the medicated oil, but also enhance the synergistic effect between the medicated oil and acupuncture therapy, thereby meeting the needs of modern Chinese medicine clinics for efficient and safe acupuncture medicated oil. At the same time, the preparation method is simple to operate, does not require additional specific equipment, is suitable for mass industrial production, and has broad market prospects and promotion value.

[0007] In order to achieve the above-mentioned purpose, the technical scheme adopted by the present invention is as follows: a kind of Chinese medicine acupuncture medicated oil and its preparation method, the acupuncture medicated oil comprises the following components in parts by weight: 30-60 parts of base oil, 10-40 parts of Chinese medicine extract, 5-15 parts of penetration enhancer, 1-6 parts of antioxidant, 1-5 parts of emulsifier, 0.2-2 parts of thickener, 0.1-1 parts of preservative and 0.1-1 parts of fragrance.

[0008] Preferably, the acupuncture oil comprises the following components in parts by weight: 40-50 parts of base oil, 20-30 parts of Chinese herbal extract, 8-12 parts of penetration enhancer, 2-5 parts of antioxidant, 1-3 parts of emulsifier, 0.5-1.5 parts of thickener, 0.1-0.5 parts of preservative and 0.2-0.8 parts of fragrance.

[0009] Preferably, the base oil is compounded from the first vegetable oil, the second vegetable oil and the third vegetable oil in a weight ratio of 35:24:12.

[0010] Preferably, the first vegetable oil is olive oil, the second vegetable oil is sweet almond oil, and the third vegetable oil is grape seed oil.

[0011] Preferably, the Chinese herbal medicine extract is obtained by compounding Salvia miltiorrhiza extract, Ligusticum chuanxiong extract, Angelica sinensis extract and Carthamus tinctorius extract in a weight ratio of 1.5-2.5:1.0-1.8:0.5-1.0:0.8-1.5.

[0012] Preferably, the penetration enhancer is prepared by mixing menthol and borneol in a weight ratio of 2-3:1-2.

[0013] Preferably, the antioxidant is prepared by compounding vitamin E and tea polyphenols in a weight ratio of 1.2 to 1.8:1.

[0014] Preferably, the emulsifier is composed of lecithin and polysorbate 80 in a weight ratio of 3-5:1-2.

[0015] Preferably, the thickener is composed of xanthan gum and sodium carboxymethyl cellulose in a weight ratio of 2-3:1-2.

[0016] Preferably, the preservative is composed of phenoxyethanol and potassium sorbate in a weight ratio of 1 to 2:1.

[0017] The present invention also provides a method for preparing a Chinese medicine acupuncture oil, the preparation method comprising the following steps:

[0018] (1) ultrasonically mixing the base oil, the Chinese herbal medicine extract and the penetration enhancer to obtain a first mixed solution;

[0019] (2) subjecting the first mixed solution to low-temperature freezing treatment, and then thawing the solution and adding an antioxidant and an emulsifier to homogenize and emulsify the solution to obtain a second mixed solution;

[0020] (3) Adding a thickener and a preservative to the second mixed liquid, stirring and mixing, and then adding spices to obtain the Chinese medicine acupuncture oil.

[0021] The beneficial effects achieved by the present invention using the above structure are as follows: (1) The Chinese medicine acupuncture medicated oil and the preparation method thereof provided by the present invention have significant technical advantages and application value; (2) The unique formula design and preparation process of the present invention not only significantly improve the permeability and stability of the medicated oil, but also enhance its synergistic effect with acupuncture therapy, thereby meeting the needs of modern Chinese medicine clinical practice for efficient and safe acupuncture medicated oil; (3) The present invention is simple to operate, does not require additional specific equipment, is suitable for mass industrial production, and has broad market prospects and promotion value.

[0022] The Chinese herbal extract is one of the core active ingredients of the present invention, and its formula is compounded with Danshen extract, Chuanxiong extract, Angelica extract and Safflower extract. Danshen extract has the effect of promoting blood circulation and removing blood stasis, and can improve local blood circulation; Chuanxiong extract is known for its effect of promoting qi and promoting blood circulation, and can further enhance the penetration effect of medicinal oil; Angelica extract is rich in a variety of active ingredients, can nourish the skin and promote tissue repair; Safflower extract is widely used in the field of traditional Chinese medicine for its anti-inflammatory and analgesic properties. The scientific ratio of these four Chinese herbal extracts not only gives full play to their respective pharmacological effects, but also improves the overall efficacy through synergistic effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 The cure rate of acupuncture treatment in each group.

[0024] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used to explain the present invention together with the embodiments of the present invention and do not constitute a limitation of the present invention. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments; based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0026] Unless otherwise defined, all professional and scientific terms used herein have the same meanings as those familiar to those skilled in the art. In addition, any methods and materials similar or equivalent to those described herein may be applied to the present invention. The preferred implementation methods and materials described herein are for demonstration purposes only and are not intended to limit the content of this application.

[0027] The experimental methods in the following examples are conventional methods unless otherwise specified; the experimental materials and test strains used in the following examples are purchased from commercial channels unless otherwise specified.

[0028] Example 1

[0029] A kind of medicinal oil for traditional Chinese medicine acupuncture and moxibustion and preparation method thereof

[0030] The acupuncture oil comprises the following components in parts by weight: 40 parts of base oil, 30 parts of Chinese herbal extract, 8 parts of penetration enhancer, 5 parts of antioxidant, 1 part of emulsifier, 1.5 parts of thickener, 0.1 parts of preservative and 0.8 parts of fragrance.

[0031] The base oil is compounded by a first vegetable oil, a second vegetable oil and a third vegetable oil in a weight ratio of 35:24:12.

[0032] Wherein, the first vegetable oil is olive oil, the second vegetable oil is sweet almond oil, and the third vegetable oil is grape seed oil.

[0033] The Chinese medicine extract is obtained by compounding salvia miltiorrhiza extract, chuanxiong extract, angelica extract and safflower extract in a weight ratio of 1.5:1.8:0.5:1.5.

[0034] The penetration enhancer is prepared by mixing menthol and borneol in a weight ratio of 1:1.

[0035] The antioxidant is prepared by compounding vitamin E and tea polyphenols in a weight ratio of 1.2:1.

[0036] Wherein, the emulsifier is composed of lecithin and polysorbate-80 in a weight ratio of 3:1.

[0037] Wherein, the thickener is composed of xanthan gum and sodium carboxymethyl cellulose in a weight ratio of 3:2.

[0038] Wherein, the preservative is composed of phenoxyethanol and potassium sorbate in a weight ratio of 1:1.

[0039] The present invention also provides a method for preparing a Chinese medicine acupuncture oil, the preparation method comprising the following steps:

[0040] (1) ultrasonically mixing the base oil, the Chinese herbal medicine extract and the penetration enhancer to obtain a first mixed solution;

[0041] (2) subjecting the first mixed solution to low-temperature freezing treatment, and then thawing the solution and adding an antioxidant and an emulsifier to homogenize and emulsify the solution to obtain a second mixed solution;

[0042] (3) Adding a thickener and a preservative to the second mixed liquid, stirring and mixing, and then adding spices to obtain the Chinese medicine acupuncture oil.

[0043] Example 2

[0044] A kind of medicinal oil for traditional Chinese medicine acupuncture and moxibustion and preparation method thereof

[0045] The acupuncture oil comprises the following components in parts by weight: 50 parts of base oil, 20 parts of Chinese herbal extract, 12 parts of penetration enhancer, 2 parts of antioxidant, 3 parts of emulsifier, 0.5 parts of thickener, 0.5 parts of preservative and 0.2 parts of fragrance.

[0046] The base oil is compounded by a first vegetable oil, a second vegetable oil and a third vegetable oil in a weight ratio of 35:24:12.

[0047] Wherein, the first vegetable oil is olive oil, the second vegetable oil is sweet almond oil, and the third vegetable oil is grape seed oil.

[0048] The Chinese medicine extract is prepared by compounding salvia miltiorrhiza extract, chuanxiong rhizome extract, angelica sinensis extract and safflower extract in a weight ratio of 2.5:1.8:1.0:1.5.

[0049] The penetration enhancer is prepared by mixing menthol and borneol in a weight ratio of 3:2.

[0050] The antioxidant is prepared by compounding vitamin E and tea polyphenols in a weight ratio of 1.8:1.

[0051] Wherein, the emulsifier is composed of lecithin and polysorbate-80 in a weight ratio of 5:2.

[0052] Wherein, the thickener is composed of xanthan gum and sodium carboxymethyl cellulose in a weight ratio of 3:2.

[0053] Wherein, the preservative is composed of phenoxyethanol and potassium sorbate in a weight ratio of 2:1.

[0054] The present invention also provides a method for preparing a Chinese medicine acupuncture oil, and the preparation method is carried out with reference to Example 1.

[0055] Example 3

[0056] A kind of medicinal oil for traditional Chinese medicine acupuncture and moxibustion and preparation method thereof

[0057] The acupuncture medicated oil comprises the following components in parts by weight: 45 parts of base oil, 25 parts of Chinese herbal extract, 10 parts of penetration enhancer, 3 parts of antioxidant, 2 parts of emulsifier, 1 part of thickener, 0.8 parts of preservative and 0.5 parts of fragrance.

[0058] The base oil is compounded by a first vegetable oil, a second vegetable oil and a third vegetable oil in a weight ratio of 35:24:12.

[0059] Wherein, the first vegetable oil is olive oil, the second vegetable oil is sweet almond oil, and the third vegetable oil is grape seed oil.

[0060] The Chinese medicine extract is obtained by compounding salvia miltiorrhiza extract, chuanxiong extract, angelica extract and safflower extract in a weight ratio of 2:1.4:0.8:1.3.

[0061] The penetration enhancer is prepared by mixing menthol and borneol in a weight ratio of 2.5:1.

[0062] The antioxidant is prepared by compounding vitamin E and tea polyphenols in a weight ratio of 1.6:1.

[0063] Wherein, the emulsifier is composed of lecithin and polysorbate-80 in a weight ratio of 4:1.

[0064] Wherein, the thickener is composed of xanthan gum and sodium carboxymethyl cellulose in a weight ratio of 2.5:1.

[0065] Wherein, the preservative is composed of phenoxyethanol and potassium sorbate in a weight ratio of 1.5:1.

[0066] The present invention also provides a method for preparing a Chinese medicine acupuncture oil, and the preparation method is carried out with reference to Example 1.

[0067] Experimental Example 1

[0068] 200 patients who met the indications for acupuncture treatment were selected and randomly divided into Example 1-3 group and control group, with 50 cases in each group. Example 1-3 group adopted the Chinese medicine acupuncture oil prepared by the present invention in combination with acupuncture treatment, and the control group only adopted conventional acupuncture treatment. There was no significant difference (P>0.05) between the two groups of patients in terms of age, gender, severity of the disease, etc., and they were comparable; before acupuncture, Example 1-3 group evenly applied the medicine oil of the present invention to the acupuncture points and the surrounding skin, and gently massaged until the skin was slightly warm; the control group directly performed acupuncture operation. Both groups were treated 3 times a week, 10 times as a course of treatment, and two courses of treatment were treated in total, and the recovery rate of patients in each group was counted.

[0069] Result analysis: Figure 1 As shown, the cure rates of patients in Example 1-3 groups are at a relatively high level, among which the cure rate of Example 3 group is the highest, while the cure rate of the control group is relatively low.

[0070] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

[0071] The present invention and its embodiments are described above, and such description is not restrictive. The drawings show only one embodiment of the present invention, and the actual structure is not limited thereto. In short, if ordinary technicians in the field are inspired by it, without departing from the purpose of the invention, they can design a structure and embodiment similar to the technical solution without creativity, which should belong to the protection scope of the present invention.

Claims

1. A medicinal oil for traditional Chinese medicine acupuncture, characterized in that: The acupuncture oil comprises the following components in parts by weight: 30-60 parts of base oil, 10-40 parts of Chinese herbal extract, 5-15 parts of penetration enhancer, 1-6 parts of antioxidant, 1-5 parts of emulsifier, 0.2-2 parts of thickener, 0.1-1 parts of preservative and 0.1-1 parts of fragrance.

2. A Chinese medicine acupuncture oil according to claim 1, characterized in that: The acupuncture oil comprises the following components in parts by weight: 40-50 parts of base oil, 20-30 parts of Chinese herbal extract, 8-12 parts of penetration enhancer, 2-5 parts of antioxidant, 1-3 parts of emulsifier, 0.5-1.5 parts of thickener, 0.1-0.5 parts of preservative and 0.2-0.8 parts of fragrance.

3. A Chinese medicine acupuncture oil according to claim 2, characterized in that: The base oil is compounded by mixing the first vegetable oil, the second vegetable oil and the third vegetable oil in a weight ratio of 35:24:

12.

4. A Chinese medicine acupuncture oil according to claim 3, characterized in that: The first vegetable oil is olive oil, the second vegetable oil is sweet almond oil, and the third vegetable oil is grape seed oil.

5. A Chinese medicine acupuncture oil according to claim 4, characterized in that: The Chinese medicine extract is obtained by compounding salvia miltiorrhiza extract, chuanxiong extract, angelica extract and safflower extract in a weight ratio of 1.5-2.5:1.0-1.8:0.5-1.0:0.8-1.

5.

6. A Chinese medicine acupuncture oil according to claim 5, characterized in that: The penetration enhancer is prepared by mixing menthol and borneol in a weight ratio of 2-3:1-2.

7. A Chinese medicine acupuncture oil according to claim 6, characterized in that: The antioxidant is prepared by compounding vitamin E and tea polyphenols in a weight ratio of 1.2 to 1.8:

1.

8. A Chinese medicine acupuncture oil according to claim 7, characterized in that: The emulsifier is composed of lecithin and polysorbate-80 in a weight ratio of 3-5:1-2.

9. A Chinese medicine acupuncture oil according to claim 8, characterized in that: The thickener consists of xanthan gum and sodium carboxymethyl cellulose; and the preservative consists of phenoxyethanol and potassium sorbate.

10. A method for preparing the Chinese medicine oil for acupuncture and moxibustion according to claim 9, characterized in that: The preparation method comprises the following steps: (1) ultrasonically mixing the base oil, the Chinese herbal medicine extract and the penetration enhancer to obtain a first mixed solution; (2) subjecting the first mixed solution to low-temperature freezing treatment, and then thawing the solution and adding an antioxidant and an emulsifier to homogenize and emulsify the solution to obtain a second mixed solution; (3) Adding a thickener and a preservative to the second mixed liquid, stirring and mixing, and then adding spices to obtain the Chinese medicine acupuncture oil.

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