Variable-pressure low-residue multilayer medicine tablet press

By designing a multi-layer pharmaceutical tablet press, including drug input, extrusion molding, pressure regulation, vibration and discharge mechanism, the problem of single-layer pharmaceutical tablet machine processing multi-layer tablet press is solved, uniform molding and appropriate pressure of the tablet are achieved, and the flexibility and quality of drug production are improved.

CN120096133AInactive Publication Date: 2025-06-06JIANGSU DONGBEN MASCH TECH CO LTD
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Patent Information

Application Number
CN202510422946.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-07
Publication Date
2025-06-06
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The existing single-layer pharmaceutical tablet press cannot effectively handle multi-layer tablets, resulting in poor tablet molding, uneven drug distribution and inability to regulate pressure, limiting the flexibility and innovation of drug production.

Method used

A multi-layer pharmaceutical tablet press with low residual variable pressure is designed, including a drug input mechanism, an extrusion molding mechanism, a pressure adjustment mechanism, a vibration mechanism and an exhaust mechanism. Through multiple sets of extrusion equipment and an adjustable extrusion mold size, effective extrusion molding of multi-layer tablets is achieved, and drug uniformity and appropriate pressure are ensured through vibration and pressure adjustment techniques.

Benefits of technology

The effective extrusion molding of multi-layer tablets is achieved, ensuring the uniformity of drug distribution and the appropriateness of pressure, improving the appearance quality and stability of the tablets, and enhancing the flexibility and innovation of drug production.

✦ Generated by Eureka AI based on patent content.

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Abstract

A variable-pressure low-residue multilayer medicine tabletting machine belongs to the technical field of medicine tabletting and comprises a medicine feeding mechanism, an extrusion forming mechanism, a pressure adjusting mechanism, a vibrating mechanism, a discharging mechanism and other mechanisms. The medicine feeding mechanism, the extrusion forming mechanism, the pressure adjusting mechanism, the vibration mechanism, the discharging mechanism and part of other mechanisms are combined into multiple sets of extrusion equipment, according to the number of layers of tablets, extrusion molds in the extrusion equipment are different in size, and therefore different layers of the tablets can be extruded; the medicine feeding mechanism, the extrusion forming mechanism, the pressure adjusting mechanism, the vibration mechanism, the discharging mechanism and part of other mechanisms are combined to form multiple sets of extrusion equipment, according to the number of layers of tablets, different combinations are used for the tablets with different number of layers, and the sizes of extrusion molds in the extrusion equipment are different, so that different layers of the tablets can be extruded, and the tablet forming efficiency is improved. And multi-layer medicine tabletting is realized through extrusion equipment in different combinations.
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Description

Technical Field

[0001] The invention relates to the technical field of medicine tablet pressing, in particular to a multi-layer medicine tablet pressing machine with variable pressure and low residue. Background Art

[0002] The existing tablet presses are mostly limited to a single-layer tablet press function, which is obviously difficult to meet the diversified needs of current drug production. In the field of modern medicine, multi-layer tablets are gradually becoming the mainstream. Each layer of tablets can carry different drug ingredients. This design not only facilitates patients' absorption and swallowing, but also achieves precise control of drug release and improves the therapeutic effect. However, the single-layer tablet press is unable to effectively extrude multi-layer tablets, which undoubtedly limits the flexibility and innovation of drug production.

[0003] What is even more troublesome is that during the use of today's single-layer pharmaceutical tablet presses, due to the limitations of mold design or tableting process, tablets are sometimes difficult to remove smoothly from the mold, further reducing production efficiency. In addition, single-layer pharmaceutical tablet presses also have the problem of uneven drug distribution during the extrusion process. This will lead to poor tablet molding, and even cracks and breakage, which seriously affects the appearance quality and stability of the tablets. For multi-layer tablets that require precise control of drug content, this unevenness is even more unacceptable.

[0004] More importantly, existing pharmaceutical tablet presses are often unable to effectively adjust pressure. Different drug ingredients may require different pressures to achieve the best extrusion effect, but a single-layer tablet press cannot meet this demand. This results in the same density of drugs in different layers of extruded tablets, which cannot be personalized according to the characteristics of the drugs. This "one-size-fits-all" tableting method is obviously not conducive to the melting and absorption of the outer layer of drugs, and may also affect the release rate and effect of the drugs in the body. Summary of the invention

[0005] In view of the above problems, the present invention provides a variable pressure low residue multi-layer pharmaceutical tablet press to solve the problems raised in the background technology.

[0006] The technical solution used in the present invention is: a variable pressure low residue multi-layer pharmaceutical tablet press, comprising a drug feeding mechanism, an extrusion molding mechanism, a pressure regulating mechanism, a vibration mechanism, a discharge mechanism and other mechanisms; the drug feeding mechanism, the extrusion molding mechanism, the pressure regulating mechanism, the vibration mechanism, the discharge mechanism and part of the other mechanisms are combined into an extrusion device, and the extrusion device has multiple groups, which are determined according to the number of layers of the tablets. Tablets with different numbers of layers use different combinations of extrusion devices, and the extrusion dies in the extrusion device are of different sizes, so that different layers of the tablets can be extruded; The extrusion molding mechanism includes an extrusion mold for extruding and molding tablets and a mold limiting plate on which the extrusion mold is installed; the pressure regulating mechanism includes an adjusting threaded rod for adjusting the distance between the first pressing plate and the second pressing plate, an adjusting knob threadedly connected to the adjusting threaded rod, and a chain group connecting multiple adjusting knobs together to achieve synchronous rotation; the vibration mechanism includes a power ring installed in the middle layer of the mold limiting plate and driven to rotate by power, multiple vibration control rings that are rotatably installed in the middle layer of the mold limiting plate and meshed with the power ring, and a vibration hammer with convex plates at the upper and lower ends that contact the inner wall of the vibration control ring and is connected to the mold limiting plate through a spring to knock on the outer wall of the extrusion mold to vibrate the extrusion mold.

[0007] Preferably, the drug injection mechanism includes a medicine placement box for placing medicines, a box cover covering the medicine placement box to prevent dust from falling into the medicine placement box, a medicine feed pipe with one end fixedly installed in a hole provided on the inner side of the medicine placement box and provided with a valve for controlling the discharge of medicines, a medicine feed pipe fixing plate on which the medicine feed pipe is fixedly installed, and a circular plate that is slidably connected to the medicine feed pipe fixing plate and is provided with a cylinder for pushing the medicine feed pipe fixing plate to move.

[0008] Preferably, the drug inlet tube is installed on one end of the drug inlet tube fixing plate and the opening gradually narrows, so as to facilitate the discharge of the drug into the extrusion mold and prevent the drug from spilling outside the extrusion mold; a stirring plate for stirring the drug in the drug placement box is provided under the box cover, so as to completely discharge the drug in the drug placement box into the drug inlet tube.

[0009] Preferably, the extrusion molding mechanism also includes a hydraulic pump, a downward pressing plate fixedly connected to the hydraulic pump push rod, which passes through the equipment from the middle and connects the two downward pressing connecting shafts of the two downward pressing plates provided in the two-layer extrusion equipment, a downward pressing second plate provided with a sliding hole in the middle and slidably connected to the downward pressing connecting shaft, a plurality of extrusion columns connected at the upper ends by a connecting frame, and an extrusion pad provided with a cylinder for supporting the extrusion of medicines.

[0010] Preferably, the cylinder on the extrusion pad is used to push the extrusion pad to separate from the extrusion die, so as to facilitate the removal of the tablets formed in the extrusion die. At the same time, a discharge hole for discharging the tablets is provided on the extrusion pad. After the extrusion pad moves downward, the discharge hole contacts the upper end of the discharge barrel, so as to facilitate the discharge of the tablets from the discharge hole into the discharge barrel. The size and shape of the lower end of the extrusion column are the same as those of the extrusion die, and the extrusion column and the extrusion die are tightly matched.

[0011] Preferably, the discharge mechanism includes a medicine scraper rack provided with a shaft and connected to the power through gears, and is provided with a plurality of movable clamps corresponding to the number of the extrusion dies and used to push the tablets to move, and a medicine discharge barrel with a trumpet shape on the top for receiving the tablets discharged from the discharge hole of the extrusion pad.

[0012] Preferably, the drug discharge cylinder arranged in the last layer of extrusion equipment discharges the tablets out of the equipment, and the drug discharge cylinder arranged in the extrusion equipment of the next layer discharges the medicines into the drug inlet pipe of the next layer of extrusion equipment.

[0013] Preferably, other mechanisms include an outer cylinder bottom plate serving as the outer shell of the device, a top cover covering the top of the device and fixedly connected to the outer cylinder bottom plate, and an outer cylinder fixedly installed at the lower end of the outer cylinder bottom plate, which is used to support the entire device and facilitate the discharge of extruded tablets.

[0014] Beneficial effects of the present invention: 1. The drug feeding mechanism, extrusion molding mechanism, pressure regulating mechanism, vibration mechanism, discharge mechanism and some other mechanisms are combined into an extrusion device. There are multiple groups of extrusion devices, which are determined by the number of layers of the tablets. Tablets with different numbers of layers use different combinations. The extrusion dies in the extrusion device are of different sizes, so that different layers of the tablets can be extruded. Through different combinations of extrusion devices, multi-layer drug tableting is achieved; 2. When the drug enters the extrusion die, the power ring rotates and drives the vibration hammer to reciprocate, knocking the extrusion die to evenly disperse the drug into the extrusion die, and expel the air in the drug, making the drug more uniform and facilitating the extrusion molding of the drug. At the same time, the vibration hammer reciprocates and knocks the extrusion die, which can vibrate the tablets off the extrusion die, and then separate the tablets from the extrusion die. The vibration makes the drug more uniform and facilitates the demolding of the tablets; 3. Adjust the threaded rod to drive the second pressing plate to move, adjust the distance between the first pressing plate and the second pressing plate, control the position of the extrusion column through the second pressing plate, and then control the distance of the extrusion column entering the extrusion die, and control the pressure of the extrusion column to extrude the medicine, so that different types of pressure can be used according to different types of medicines, which is convenient for the subsequent use of medicines; 4. The cylinder arranged under the medicine inlet pipe fixing plate drives the medicine inlet pipe fixing plate to move downward, and then drives the medicine inlet pipe to move downward to insert the lower end of the medicine inlet pipe into the extrusion die. At this time, the valve in the medicine inlet pipe opens to discharge the medicine in the medicine inlet pipe into the extrusion die. The lower end of the medicine inlet pipe is inserted into the extrusion die to discharge the medicine to avoid the medicine being discharged outside the extrusion die. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a structural schematic diagram of the overall structure of the present invention.

[0016] Figure 2 It is a schematic cross-sectional structure diagram of the overall structure of the present invention.

[0017] Figure 3 It is a schematic diagram of the cross-sectional structure of the upper extrusion equipment of the present invention.

[0018] Figure 4It is a structural schematic diagram of the connection position of two extrusion devices of the present invention.

[0019] Figure 5 It is a schematic structural diagram of the top cover and its adjacent parts of the present invention.

[0020] Figure 6 For the present invention Figure 5 Schematic diagram of the cross-sectional structure.

[0021] Figure 7 It is a structural schematic diagram of the extrusion molding mechanism, the circular ring plate and its surrounding parts of the present invention.

[0022] Figure 8 It is a schematic structural diagram of the extrusion molding mechanism and its adjacent parts of the present invention.

[0023] Fig. 9 It is a schematic structural diagram of the lower parts of the extrusion equipment of the present invention.

[0024] Fig.10 It is a schematic structural diagram of the die limiting plate, the extrusion die and the power sleeve of the present invention.

[0025] Fig.11 It is a schematic structural diagram of the extrusion die, vibration control ring and vibration hammer of the present invention.

[0026] Fig.12 It is a schematic structural diagram of the extrusion die, a single vibration control ring and a vibration hammer of the present invention.

[0027] Fig.13 It is a schematic structural diagram of the medicine scraping frame, medicine discharging cylinder and nearby parts of the present invention.

[0028] Figure numerals: 1. Top cover; 2. Medicine placement box; 3. Box cover; 4. Medicine inlet pipe; 5. Hydraulic pump; 6. Pressing connecting shaft; 7. Pressing one plate; 8. Pressing two plates; 9. Extrusion column; 10. Adjusting threaded rod; 11. Adjusting knob; 12. Chain set; 13. Medicine inlet pipe fixing plate; 14. Circular ring plate; 15. Mould limiting plate; 16. Extrusion mould; 17. Power sleeve; 18. Vibration control ring; 19. Vibration hammer; 20. Medicine scraper rack; 21. Extrusion pad; 22. Medicine discharge cylinder; 23. Bottom plate of outer cylinder; 24. Outer cylinder. DETAILED DESCRIPTION

[0029] The technical solution of the present invention is further specifically described below by way of embodiments and in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific implementation disclosed below.

[0030] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "upper", "lower", "front", "back", "left", "right", etc. is based on the orientation or positional relationship shown in the drawings, or the orientation or positional relationship in which the invention product is usually placed when used, which is only for the convenience of describing the simplified description of the invention patent, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the invention patent. In addition, for the convenience of explanation, spatial relative terms, such as "below", "below", "below", "above", "above", etc., may be used in the text to describe the relationship of an element or feature relative to other elements or features as shown in the figure. Spatially relative terms are intended to include different orientations of the device in use or operation other than the orientation shown in the drawings. The device may have other orientations (rotated 90 degrees or in other orientations), and the spatially relative descriptors used in the text may also be interpreted accordingly. It should be noted that in this article, some connection methods, such as "fixed connection, fixed installation" refer to, but are not limited to, the fixing of two parts such as welding, screw and nut fixing, gluing, riveting, interference fit, etc. between two parts. For those skilled in the art, the specific meanings of the above terms in this application can be understood based on specific circumstances.

[0031] In order to facilitate the understanding of the present invention, the present invention will be described more fully below with reference to the relevant drawings. The preferred embodiments of the present invention are given in the drawings. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present invention more thoroughly understood.

[0032] Example: Figure 1-Figure 13 As shown, a variable pressure low residue multi-layer pharmaceutical tablet press comprises a drug feeding mechanism, an extrusion molding mechanism, a pressure regulating mechanism, a vibration mechanism, a discharge mechanism and other mechanisms; the drug feeding mechanism, the extrusion molding mechanism, the pressure regulating mechanism, the vibration mechanism, the discharge mechanism and part of the other mechanisms are combined into an extrusion device, and the extrusion dies 16 in the extrusion device are of different sizes, so that different layers of tablets can be extruded; there are multiple groups of extrusion devices, which are determined according to the number of layers of the tablets, and tablets with different numbers of layers use different combinations of extrusion devices.

[0033] Example: Figure 3 , Figure 5 , Figure 6As shown, the drug feeding mechanism includes: a drug placement box 2, a box cover 3, a drug inlet pipe 4, a drug inlet pipe fixing plate 13, and a circular ring plate 14; the drug placement box 2 is used to place drugs, and the drug placement box 2 is fixedly connected to the outer cylinder bottom plate 23, and the inner side of the drug placement box 2 is provided with a plurality of holes for installing the drug inlet pipe 4; one end of the drug inlet pipe 4 is fixedly installed in the hole provided on the inner side of the drug placement box 2, and the other end is fixedly installed on the drug inlet pipe fixing plate 13, and the opening of one end of the drug inlet pipe fixing plate 13 is gradually reduced, so as to facilitate the discharge of drugs into the extrusion die 16 and prevent the drugs from spilling outside the extrusion die 16; the box cover 3 covers the top of the drug placement box 2 to prevent dust from falling into the drug placement box 2, and the box cover 3 is provided with a The stirring plate for stirring the medicine in the medicine placement box 2 is used to completely discharge the medicine in the medicine placement box 2 into the medicine inlet pipe 4; at the same time, a valve that can control the discharge of medicine is also provided in the medicine inlet pipe 4, which is used to control the discharge and the amount of medicine discharged; the medicine inlet pipe fixing plate 13 is movably connected to the outer cylinder bottom plate 23, and at the same time, the medicine inlet pipe fixing plate 13 is connected to the power, and then the medicine inlet pipe fixing plate 13 is driven to rotate by the power; the medicine inlet pipe fixing plate 13 is provided with a plurality of holes for installing the medicine inlet pipe 4 and holes for slidingly installing the extrusion column 9, and a cylinder is provided under the medicine inlet pipe fixing plate 13, and the cylinder is fixedly connected to the circular plate 14; a sliding rod is provided on the circular plate 14 and is slidably connected to the medicine inlet pipe fixing plate 13, and the circular plate 14 is placed on the mold limiting plate 15.

[0034] Example: Figure 4 , Figure 7-Figure 9As shown, the extrusion molding mechanism includes: a hydraulic pump 5, a downward pressing connecting shaft 6, a downward pressing plate 7, a downward pressing plate 8, an extrusion column 9, a mold limiting plate 15, an extrusion mold 16, and an extrusion pad 21; the upper end of the hydraulic pump 5 is fixedly connected to the top cover 1, and the push rod of the hydraulic pump 5 is fixedly connected to the downward pressing plate 7; the downward pressing connecting shaft 6 passes through the equipment from the middle of the equipment and is connected to the downward pressing plate 7 in the next layer of extrusion equipment, so as to facilitate the control of multiple extrusion equipment by the hydraulic pump 5 for extrusion operation; a sliding hole is provided in the middle of the downward pressing plate 8 to be slidably connected to the downward pressing connecting shaft 6, and a circular sliding groove is provided at the lower end of the downward pressing plate 8; the extrusion column 9 has a plurality of upper ends of the extrusion columns 9 connected by a connecting frame, and the connecting frame is slidably installed in the circular sliding groove provided at the lower end of the downward pressing plate 8; the extrusion column 9 passes through the medicine inlet pipe fixing plate 13 and contacts with the mold limiting plate 15; the mold limiting plate 15 is fixedly connected to the outer cylinder bottom plate 23, and the mold limiting plate 15 is provided with a plurality of The hole for installing the extrusion die 16 is provided with a groove for installing the vibration control ring 18 and the vibration hammer 19 on the hole wall; and the outer wall of the die limiting plate 15 is provided with a groove for rotatably installing the power sleeve 17; the extrusion pad 21 is slidably connected with the outer cylinder bottom plate 23, and at the same time, the extrusion pad 21 is provided with a cylinder fixedly installed on the outer wall of the outer cylinder bottom plate 23, and the cylinder is used to push the extrusion pad 21 and the extrusion die 16 to separate, so as to facilitate the removal of the tablets formed in the extrusion die 16; the extrusion pad 21 is provided with a discharge hole for discharging tablets, when the extrusion pad 21 moves downward under the push of the cylinder, the discharge hole of the extrusion pad 21 contacts the upper end of the discharge barrel 22, so as to facilitate the discharge of the tablets from the discharge hole into the discharge barrel 22; the size and shape of the lower end of the extrusion column 9 are the same as those of the extrusion die 16, so as to facilitate the insertion of the extrusion column 9 into the extrusion die 16, so that the extrusion column 9 and the extrusion die 16 are closely matched, so as to facilitate the extrusion molding of the tablets.

[0035] Example: Figure 7 , Figure 8 As shown, the pressure regulating mechanism includes: an adjusting threaded rod 10, an adjusting knob 11, and a chain group 12; the lower end of the adjusting threaded rod 10 is fixedly connected to the second pressing plate 8, and the adjusting threaded rod 10 is threadedly connected to the adjusting knob 11; the adjusting knob 11 is rotatably installed in a hole provided on the first pressing plate 7, and the adjusting knob 11 passes through the first pressing plate 7. The lower ends of multiple adjusting knobs 11 are connected together by a chain group 12, and the adjusting knobs 11 are synchronously rotated by the chain group 12, thereby driving the adjusting threaded rod 10 to move synchronously; the movement of the adjusting threaded rod 10 will drive the second pressing plate 8 to move, and then the distance between the first pressing plate 7 and the second pressing plate 8 can be adjusted, so that the position of the extrusion column 9 can be controlled by the second pressing plate 8, and then the distance of the extrusion column 9 entering the extrusion die 16 can be controlled, and then the pressure of the extrusion column 9 to extrude the medicine can be controlled, so that different types of pressure can be used according to different types of medicines, which is convenient for the subsequent absorption of the medicine in the human body.

[0036] Example: Fig.11 , Fig.12 As shown, the vibration mechanism includes: a power collar 17, a vibration control ring 18, and a vibration hammer 19; the power collar 17 is rotatably installed in the middle position of the mold limiting plate 15, and the power collar 17 is connected to the power, and the power collar 17 is driven to rotate by the power; there are multiple vibration control rings 18, one extrusion mold 16 is matched with two vibration control rings 18, the vibration control ring 18 is meshed with the power collar 17, and then the vibration control ring 18 can be driven to rotate around the extrusion mold 16 through the power collar 17, and the vibration control ring 18 is rotatably installed in the middle position of the mold limiting plate 15; a sliding rod is provided at the rear end of the vibration hammer 19 to be slidably connected to the mold limiting plate 15, and a spring is wrapped around the sliding rod, and the other end of the spring is connected to the mold limiting plate 15 is connected, and the spring provides a pulling force to reset the vibration hammer 19. The upper and lower ends of the vibration hammer 19 are provided with convex plates, and the two convex plates are in contact with the inner wall of the vibration control ring 18; the interior of the vibration control ring 18 is uneven, and the uneven shape pushes the vibration hammer 19 to move, and is used in conjunction with the spring provided on the sliding rod of the vibration hammer 19 to make the vibration hammer 19 move back and forth, and then the vibration hammer 19 knocks the outer wall of the extrusion die 16, and then the extrusion die 16 is vibrated, which is convenient for evenly distributing the medicines in the extrusion die 16 and facilitating extrusion molding. The tablets extruded in the extrusion die 16 can also be separated from the extrusion die 16, so that the tablets can be taken out of the extrusion die 16.

[0037] Example: Fig.10 , Fig.13 As shown, the discharge mechanism includes: a medicine scraper frame 20 and a medicine discharge barrel 22; an axis is provided in the middle of the medicine scraper frame 20, and a through hole is provided in the middle of the axis for passing the downward pressing connecting shaft 6; the axis provided in the middle of the medicine scraper frame 20 is connected to the power through a gear, and then the medicine scraper frame 20 is driven to rotate by the power, and the medicine scraper frame 20 is provided with a plurality of clamps for pushing the tablets to move, and the number of the clamps corresponds to the number of the extrusion molds 16; the medicine discharge barrel 22 is fixedly connected to the bottom plate 23 of the outer cylinder, and the medicine discharge barrel 22 is trumpet-shaped, which is convenient for receiving the tablets discharged by the extrusion mold 16 and pushed to the discharge hole position of the extrusion pad 21 by the medicine scraper frame 20. The lower end of the medicine discharge barrel 22 is used to discharge the tablets and discharge the medicines into the medicine inlet pipe 4 of the next layer of extrusion equipment. At the same time, the medicine discharge barrel 22 in the last layer of extrusion equipment discharges the tablets out of the equipment.

[0038] Example: Figure 1-Figure 3 As shown, other mechanisms include: a top cover 1, an outer cylinder bottom plate 23, and an outer cylinder 24; the top cover 1 is covered at the top of the device and fixedly connected to the outer cylinder bottom plate 23 at the top; the outer cylinder bottom plate 23 is the outer shell of the device, and the two outer cylinder bottom plates 23 are connected up and down to form a whole; the outer cylinder 24 is fixedly installed at the lower end of the lowest outer cylinder bottom plate 23, which is used to support the entire device and facilitate the discharge of extruded tablets.

[0039] Working principle: When tablets need to be manufactured, the device is used to first put different layers of medicines of tablets into different medicine placing boxes 2, and then the medicines in the medicine placing boxes 2 enter the medicine inlet pipe 4, and the cylinder arranged under the medicine inlet pipe fixing plate 13 drives the medicine inlet pipe fixing plate 13 to move downward, and then drives the medicine inlet pipe 4 to move downward to insert the lower end of the medicine inlet pipe 4 into the extrusion die 16, then the valve in the medicine inlet pipe 4 is opened, and the medicine in the medicine inlet pipe 4 is discharged into the extrusion die 16, and then the cylinder arranged under the medicine inlet pipe fixing plate 13 drives the medicine inlet pipe fixing plate 13 to move upward, and then the medicine inlet pipe 4 is taken out of the extrusion die 16, and then the power connected to the medicine inlet pipe fixing plate 13 drives the medicine inlet pipe fixing plate 13 to rotate, and then drives the extrusion column 9 to rotate, so as to rotate the extrusion column 9 to the position of the extrusion die 16; At this time, the hydraulic pump 5 pushes the first pressing plate 7 to drive the second pressing plate 8 to move downward through the adjusting knob 11, and then pushes the extrusion column 9 downward, and then the extrusion column 9 enters the extrusion die 16 to extrude the medicine, and then extrude the tablet. After the extrusion is completed, the hydraulic pump 5 drives the adjusting knob 11 through the first pressing plate 7 and then drives the second pressing plate 8 to move upward, thereby driving the extrusion column 9 to move upward, and taking the extrusion column 9 out of the extrusion die 16. At this time, the power connected to the power collar 17 drives the power collar 17 to rotate, and then drives the vibration control ring 18 to rotate around the extrusion die 16, thereby driving the vibration hammer 19 to reciprocate, and then the vibration hammer 19 knocks the extrusion die 16, vibrates the tablet off the extrusion die 16, and then separates the tablet from the extrusion die 16. At this time, the gas connected to the extrusion pad 21 drives the extrusion pad 21 to move downward, and then drives the medicine scraper 20 to move downward; The extrusion pad 21 moves downward to separate the extrusion pad 21 from the extrusion die 16. At this time, the tablets in the extrusion die 16 fall onto the extrusion pad 21. Then, the power connected to the scraper rack 20 drives the scraper rack 20 to rotate, and then pushes the tablets placed on the extrusion pad 21 to the position of the discharge hole set on the extrusion pad 21. At this time, the tablets are discharged from the discharge hole set on the extrusion pad 21 into the discharge barrel 22, and then enter the drug feed pipe 4 in the next layer of extrusion equipment through the discharge barrel 22. Then, the medicines placed in the next layer of extrusion equipment are mixed into the next extrusion die 16 through the drug feed pipe 4, and enter the second layer of tablet extrusion. The above operation is performed to extrude the second layer of the tablet, and then the third layer of the tablet is extruded in the same way. Tablets of different layers can be extruded through the above process; When the drug enters the extrusion die 16, the power connected to the power ring 17 drives the power ring 17 to rotate, and then drives the vibration control ring 18 to rotate around the extrusion die 16, thereby driving the vibration hammer 19 to reciprocate, and then the vibration hammer 19 knocks the extrusion die 16, so that the drug is evenly dispersed in the extrusion die 16, and the air in the drug is discharged, so that the drug is more uniform, which is convenient for the extrusion molding of the drug; Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the invention, and the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A variable pressure low residue multi-layer pharmaceutical tablet press, comprising a drug feeding mechanism, an extrusion molding mechanism, a pressure regulating mechanism, a vibration mechanism, a discharge mechanism and other mechanisms; characterized in that: The drug feeding mechanism, extrusion molding mechanism, pressure regulating mechanism, vibration mechanism, discharge mechanism and some other mechanisms are combined into an extrusion device. There are multiple groups of extrusion devices, which are determined according to the number of layers of the tablets. Tablets with different numbers of layers use different combinations of extrusion devices. The extrusion dies (16) in the extrusion device are of different sizes, so that different layers of the tablets can be extruded. The extrusion molding mechanism comprises an extrusion die (16) for extruding tablets and a die limiting plate (15) for mounting the extrusion die (16); The pressure adjustment mechanism comprises an adjustment threaded rod (10) for adjusting the distance between the first pressing plate (7) and the second pressing plate (8), an adjustment knob (11) threadedly connected to the adjustment threaded rod (10), and a chain group (12) for connecting a plurality of adjustment knobs (11) together to achieve synchronous rotation; The vibration mechanism comprises a power sleeve (17) mounted at a middle position of a mold limiting plate (15) and driven to rotate by power, a plurality of vibration control rings (18) mounted at a middle position of the mold limiting plate (15) and meshing with the power sleeve (17), and a vibration hammer (19) having convex plates at upper and lower ends that contact the inner wall of the vibration control ring (18) and connected to the mold limiting plate (15) via a spring for striking the outer wall of the extrusion mold (16) to vibrate the extrusion mold (16).

2. A variable pressure low residue multi-layer pharmaceutical tablet press according to claim 1, characterized in that: The drug feeding mechanism comprises a drug placement box (2) for placing drugs, a box cover (3) covering the drug placement box (2) to prevent dust from falling into the drug placement box (2), a drug inlet pipe (4) having one end fixedly mounted in a hole provided on the inner side of the drug placement box (2) and provided with a valve for controlling drug discharge, a drug inlet pipe fixing plate (13) fixedly mounted with the drug inlet pipe (4), and a circular ring plate (14) slidably connected to the drug inlet pipe fixing plate (13) and provided with a cylinder for pushing the drug inlet pipe fixing plate (13) to move.

3. A variable pressure low residue multi-layer pharmaceutical tablet press according to claim 2, characterized in that: The drug inlet pipe (4) is installed on the drug inlet pipe fixing plate (13) and has an opening which gradually narrows, so as to facilitate the discharge of the drug into the extrusion die (16) and prevent the drug from spilling outside the extrusion die (16); a stirring plate for stirring the drug in the drug placement box (2) is provided under the box cover (3) so as to completely discharge the drug in the drug placement box (2) into the drug inlet pipe (4).

4. The variable pressure and low residue multi-layer pharmaceutical tablet press according to claim 1, characterized in that: The extrusion molding mechanism also includes a hydraulic pump (5), a first pressing plate (7) fixedly connected to a push rod of the hydraulic pump (5), a pressing connecting shaft (6) that penetrates the equipment from the middle of the equipment and connects two first pressing plates (7) provided in the two-layer extrusion equipment, a second pressing plate (8) provided with a sliding hole in the middle and slidably connected to the pressing connecting shaft (6), a plurality of extrusion columns (9) connected at the upper ends through a connecting frame, and an extrusion pad (21) provided with a cylinder for supporting the extrusion of medicines.

5. The variable pressure and low residue multi-layer pharmaceutical tablet press according to claim 4, characterized in that: The cylinder on the extrusion pad (21) is used to push the extrusion pad (21) to separate from the extrusion die (16), so as to facilitate the removal of the tablets formed in the extrusion die (16). At the same time, the extrusion pad (21) is provided with a discharge hole for discharging the tablets. After the extrusion pad (21) moves downward, the discharge hole contacts the upper end of the discharge barrel (22), so as to facilitate the discharge of the tablets from the discharge hole into the discharge barrel (22). The size and shape of the lower end of the extrusion column (9) are the same as those of the extrusion die (16), and the extrusion column (9) and the extrusion die (16) are tightly matched.

6. The variable pressure and low residue multi-layer pharmaceutical tablet press according to claim 1, characterized in that: The discharge mechanism comprises a medicine scraper frame (20) provided with a shaft and connected to a power source via a gear, and externally provided with a plurality of movable clamps corresponding to the number of the extrusion die (16) and used to push the movement of the tablets, and a medicine discharge barrel (22) having a trumpet-shaped upper portion for receiving the tablets discharged from the discharge hole of the extrusion pad (21).

7. A variable pressure low residue multi-layer pharmaceutical tablet press according to claim 6, characterized in that: The medicine discharge barrel (22) provided in the last layer of extrusion equipment discharges the tablets out of the equipment, and the medicine discharge barrel (22) provided in the extrusion equipment of the next layer discharges the medicines into the medicine inlet pipe (4) of the next layer of extrusion equipment.

8. The variable pressure and low residue multi-layer pharmaceutical tablet press according to claim 1, characterized in that: The other mechanisms include an outer cylinder bottom plate (23) serving as the outer shell of the device, a top cover (1) covering the top of the device and fixedly connected to the outer cylinder bottom plate (23), and an outer cylinder (24) fixedly mounted at the lower end of the outer cylinder bottom plate (23) at the bottom, used to support the entire device and facilitate the discharge of extruded tablets.