Targeted radiotherapy catheter for liver tumor

Abstract

The invention discloses a targeted radiation therapy catheter for liver tumors, relates to the technical field of targeted radiation catheter instruments, and provides the following scheme that the targeted radiation therapy catheter comprises a catheter control grip, a catheter guide mechanism is arranged at the front end of the catheter control grip, and a radiation therapy medicine conveying mechanism is arranged on the side edge of the catheter control grip; and a medicine heating mechanism is arranged at the front end of the radiotherapy medicine conveying mechanism. According to the technical scheme, the radiotherapy medicine conveying mechanism and the medicine heating mechanism are arranged, the medicine is linearly infused into the liver by controlling the infusion amount of the medicine, the medicine heating mechanism achieves the effect that the temperature of the medicine infused into the liver is close to the body temperature of the human body by heating and controlling the medicine, and therefore the effect that the medicine is directly infused into the liver is achieved. Therefore, obvious discomfort cannot be caused after the medicine enters the liver, the catheter can expand after entering the femoral artery through the catheter guiding mechanism, and the catheter is guided and driven to enter the liver in a blood flowing mode.

Description

Technical Field

[0001] The present invention relates to the technical field of targeted radiation catheter devices, and particularly to a catheter for targeted radiation therapy of liver tumors. Background Art

[0002] The progress of medical technology has promoted the rapid development and significantly increased availability of new cancer therapies. Cancer treatment involves different strategies, such as chemotherapy, surgery, radiotherapy, and recently targeted therapy, such as radionuclide-based therapies used in nuclear medicine. External radiotherapy using ionizing radiation is the most commonly used method for radiotherapy of cancer patients. In this method, the primary tumor and a limited area around it are treated by irradiating with high-energy X-rays. Another treatment option available for certain types of cancer is the use of targeted radionuclide therapy, which is based on administering radioactive substances to patients. Just like chemotherapy, this therapy is a systemic treatment that allows the radioactive substances to reach all cells in the body through blood flow.

[0003] Radioactive drugs suitable for therapeutic purposes are those that bind firmly to tumors, also known as carriers with high tumor affinity. They can deliver a targeted dose of radiation directly to the tumor and its metastases, thereby protecting normal healthy tissues from damage. In the current targeted radiation therapy of liver tumors, a thin catheter is usually used to enter the liver along the femoral artery, and then the targeted drug is infused into the liver. At present, during the process of the catheter device entering the liver along the femoral artery, it is restricted by the curvature of the blood vessels, and the process of the catheter entering the liver is relatively difficult. Moreover, since the catheter device does not have the ability to heat the targeted drug, the temperature of the drug infused into the liver is lower than the body temperature, causing discomfort to the patient. Therefore, those skilled in the art have proposed a solution for a catheter for targeted radiation therapy of liver tumors. Summary of the Invention

[0004] Aiming at the defects of the current catheter for targeted radiation therapy of liver tumors, which does not have the function of heating the therapeutic drug and is relatively difficult for the catheter to enter the liver along the femoral artery, a technical solution for a catheter for targeted radiation therapy of liver tumors is provided.

[0005] It includes a catheter control grip. A catheter guiding mechanism is provided at the front end of the catheter control grip. A radiotherapy drug delivery mechanism is provided on the side of the catheter control grip, and a drug heating mechanism is provided at the front end of the radiotherapy drug delivery mechanism; The catheter control grip includes a control grip, a data transmission line fixedly connected to the left side of the control grip, and a control knob provided on the right side wall of the control grip. A catheter interface is fixedly connected to the front side position of the right side wall of the control grip; The radiotherapy drug delivery mechanism includes a handle, a trigger movably arranged on the front side of the handle, and a connecting pipe fixed to the front end of the handle. A medicine tank connector is arranged on the left side of the connecting pipe, and a medicine tank is screwed and connected to the end port of the medicine tank connector away from the connecting pipe; The drug heating mechanism includes an upper end cover and a lower end cover. A plurality of electric heating rods are arranged between the upper end cover and the lower end cover. A catheter connecting nozzle is fixedly connected to the front end faces of the upper end cover and the lower end cover, and a nozzle is fixedly connected to the rear end faces of the upper end cover and the lower end cover; The catheter guiding mechanism includes an outer tube and a treatment catheter covered in the inner cavity of the outer tube. An oval airbag is fixedly connected to the front end of the outer tube. An outer tube end is fixedly connected to the front end of the oval airbag, and a trachea is arranged through the rear end of the oval airbag.

[0006] In the above technical solution of the hepatic tumor targeted radiotherapy catheter, preferably: Chambers for the treatment catheter to pass through are provided inside the control grip and inside the catheter interface. One end of the treatment catheter passing out of the catheter interface is fixedly connected to one end of the catheter connecting nozzle away from the upper end cover and the lower end cover.

[0007] In the above technical solution of the hepatic tumor targeted radiotherapy catheter, preferably: The front end face of the control grip is fixedly connected to the rear end face of the outer tube, and one end of the data transmission line away from the control grip is connected to the targeted radiotherapy host.

[0008] In the above technical solution of the hepatic tumor targeted radiotherapy catheter, preferably: The port of the connecting pipe away from the handle is fixedly connected to the end of the nozzle away from the upper end cover and the lower end cover.

[0009] In the above technical solution of the hepatic tumor targeted radiotherapy catheter, preferably: A drainage tube penetrating into the medicine tank is arranged inside the port of the medicine tank connector away from the connecting pipe. Threads are provided on the inner surface of the medicine tank connector, and matching threads are provided on the outer ring of the bottle mouth of the medicine tank. The inner cavity of the medicine tank is filled with a tumor targeted radiotherapy drug.

[0010] In the above technical solution of the hepatic tumor targeted radiotherapy catheter, preferably: The end faces of the upper end cover and the lower end cover close to each other are fixedly connected by a plurality of screws. A space for accommodating the electric heating rods is formed between the upper end cover and the lower end cover. A gap for the drug to flow through is provided between the inner cavity side walls of the upper end cover and the lower end cover and the outer surface of the electric heating rod.

[0011] In the above technical solution of the hepatic tumor targeted radiotherapy catheter, preferably: A plurality of through holes for the drug to flow through are provided inside the catheter connecting nozzle, and a plurality of through holes for the drug to flow through are provided inside the nozzle.

[0012] In the above technical solution of the hepatic tumor targeted radiotherapy catheter, preferably: the front and rear ends of the electric heating rod are respectively fixed on the end faces of the catheter connection nozzle and the connection nozzle close to each other, the power supply end of the electric heating rod is connected to a wire passing through the lower end cover, and a temperature sensor is installed in the inner cavities of the lower end cover and the upper end cover.

[0013] In the above technical solution of the hepatic tumor targeted radiotherapy catheter, preferably: the front end of the treatment catheter passes out from the front end port of the outer tube, and one end of the trachea far from the oval airbag is connected to a medical air pump.

[0014] In the above technical solution of the hepatic tumor targeted radiotherapy catheter, preferably: a catheter channel for the treatment catheter to pass through is provided inside the oval airbag, and a chamber for the trachea to transport gas is provided inside the oval airbag.

[0015] As can be seen from the above technical solution, compared with the prior art, the hepatic tumor targeted radiotherapy catheter provided by the present invention has the following beneficial effects: In the technical solution of the present invention, by setting up a radiotherapy drug delivery mechanism and a drug temperature raising mechanism, by controlling the drug infusion volume, linear infusion of the drug amount into the liver is achieved, and the drug temperature raising mechanism realizes that the temperature of the drug infused into the liver is close to the human body temperature by heating and controlling the temperature of the drug, so that the drug will not cause obvious discomfort after entering the liver, and the catheter guiding mechanism can make the catheter expand after entering the femoral artery, and guide and drive the catheter into the liver by means of blood flow. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce and explain the drawings required for describing the embodiments of the present invention or the prior art. Obviously, the following drawings are only partial embodiments of the present invention, and those of ordinary skill in the art can obtain other drawings based on these drawings without creative efforts.

[0017] Figure 1 It is a schematic diagram of the overall structure of the hepatic tumor targeted radiotherapy catheter; Figure 2 It is a schematic diagram of the catheter control grip; Figure 3 It is a schematic diagram of the radiotherapy drug delivery mechanism; Figure 4 It is a schematic diagram of the drug temperature raising mechanism; Figure 5 It is a schematic diagram of the catheter guiding mechanism.

[0018] AppendixFigure 1 - Attached Figure 5 The corresponding relationships of the components therein are as follows: 1. Catheter control grip; 11. Control grip; 12. Data transmission line; 13. Control knob; 14. Catheter interface; 2. Radiotherapy drug delivery mechanism; 21. Connecting tube; 22. Trigger; 23. Handle; 24. Medicine tank; 25. Medicine tank joint; 3. Drug heating mechanism; 31. Upper end cap; 32. Lower end cap; 33. Catheter connection nozzle; 34. Electric heating rod; 35. Nozzle; 4. Catheter guiding mechanism; 41. Outer tube; 42. Treatment catheter; 43. Air tube; 44. Catheter channel; 45. Oval airbag; 46. Chamber; 47. Outer tube end. Specific implementation mode

[0019] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the following described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0020] In order to more clearly explain and illustrate the technical solutions and implementation manners of the present invention, the following introduces the preferred specific embodiments for implementing the technical solutions of the present invention.

[0021] Embodiment; A preferred technical solution of a hepatic tumor targeted radiotherapy catheter: Refer to the attached drawings of the specification Figure 1 As shown: It includes a catheter control grip 1. A catheter guiding mechanism 4 is provided at the front end of the catheter control grip 1. A radiotherapy drug delivery mechanism 2 is provided on the side of the catheter control grip 1. A drug heating mechanism 3 is provided at the front end of the radiotherapy drug delivery mechanism 2; Refer to the attached drawings of the specification Figure 2 As shown: The catheter control grip 1 includes a control grip 11, a data transmission line 12 fixedly connected to the left side of the control grip 11, and a control knob 13 provided on the right side wall of the control grip 11. A catheter interface 14 is fixedly connected to the front side position of the right side wall of the control grip 11; Refer to the attached drawings of the specification Figure 3 As shown: The radiotherapy drug delivery mechanism 2 includes a handle 23, a trigger 22 movably provided in front of the handle 23, and a connecting tube 21 fixed to the front end of the handle 23. A medicine tank joint 25 is provided on the left side of the connecting tube 21. One end port of the medicine tank joint 25 away from the connecting tube 21 is screwed and connected to a medicine tank 24; Refer to the attached drawings of the specification Figure 4As shown: The drug heating mechanism 3 includes an upper end cover 31 and a lower end cover 32. Between the upper end cover 31 and the lower end cover 32, there are several electric heating rods 34 arranged. At the front end faces of the upper end cover 31 and the lower end cover 32, a catheter connecting nozzle 33 is fixedly connected. At the rear end faces of the upper end cover 31 and the lower end cover 32, a connecting nozzle 35 is fixedly connected. Refer to the attached instructions Figure 5 As shown: The catheter guiding mechanism 4 includes an outer tube 41, a treatment catheter 42 covered in the inner cavity of the outer tube 41. At the front end of the outer tube 41, an oval airbag 45 is fixedly connected. At the front end of the oval airbag 45, an outer tube end 47 is fixedly connected. A trachea 43 penetrates through the rear end of the oval airbag 45.

[0022] Refer to the attached instructions Figure 2 As shown: Chambers for the treatment catheter 42 to penetrate are provided inside both the control grip 11 and the catheter interface 14. One end of the treatment catheter 42 that penetrates out from inside the catheter interface 14 is fixedly connected to the end of the catheter connecting nozzle 33 away from the upper end cover 31 and the lower end cover 32. The front end face of the control grip 11 is fixedly connected to the rear end face of the outer tube 41. One end of the data transmission line 12 away from the control grip 11 is connected to the targeted radiotherapy host. One end port of the connecting tube 21 away from the handle 23 is fixedly connected to the end of the connecting nozzle 35 away from the upper end cover 31 and the lower end cover 32. Inside the port of the medicine tank connector 25 away from the connecting tube 21, a drainage tube that penetrates into the medicine tank 24 is provided. Threads are provided on the inner surface of the medicine tank connector 25. Threads adapted to it are provided on the outer ring of the bottle mouth of the medicine tank 24. A tumor targeted radiotherapy drug is loaded in the inner cavity of the medicine tank 24.

[0023] Refer to the attached instructions Figure 4 As shown: The end faces of the upper end cover 31 and the lower end cover 32 close to each other are fixedly connected by several screws. A space for accommodating the electric heating rods 34 is formed between the upper end cover 31 and the lower end cover 32. A gap for the drug to flow through is provided between the inner cavity side walls of the upper end cover 31 and the lower end cover 32 and the outer surface of the electric heating rod 34. Several through holes for the drug to flow through are provided inside the catheter connecting nozzle 33. Several through holes for the drug to flow through are provided inside the connecting nozzle 35. The front and rear ends of the electric heating rod 34 are respectively fixed on the side faces of the catheter connecting nozzle 33 and the connecting nozzle 35 close to each other. The power supply end of the electric heating rod 34 is connected to a wire that penetrates the lower end cover 32. Temperature sensors are installed in the inner cavities of the lower end cover 32 and the upper end cover 31.

[0024] Refer to the attached instructions Figure 5As shown: The front end of the treatment catheter 42 passes through the front end port of the outer tube 41. One end of the trachea 43 far from the elliptical airbag 45 is connected to a medical air pump. A catheter passage 44 for the treatment catheter 42 to pass through is provided inside the elliptical airbag 45, and a chamber 46 for the trachea 43 to deliver gas is provided inside the elliptical airbag 45.

[0025] According to the above-mentioned preferred technical solution content, the working process of this technical solution is described as follows: After making an incision at the femoral artery position of the patient, the front end of the catheter guiding mechanism 4 is introduced into the femoral artery. Subsequently, the trachea 43 and the medical air pump are used to slowly inflate the chamber 46 inside the elliptical airbag 45, causing the elliptical airbag 45 to slightly expand. At this time, the elliptical airbag 45 forms an "embolism" inside the femoral artery. During the blood flow inside the femoral artery, the blood pushes the elliptical airbag 45 towards the liver, thereby pulling the treatment catheter 42 and the outer tube 41 into the liver.

[0026] After injecting the targeted drug into the medicine tank 24, it is connected to the medicine tank connector 25. The targeted drug enters the inside of the connecting tube 21 along the medicine tank connector 25, and the trigger 22 controls the opening and closing angle of the valve inside the connecting tube 21 to control the slow flow of the targeted drug into the upper end cap 31 and the lower end cap 32. At this time, the electric heating rod 34 contacts the targeted drug inside the upper end cap 31 and the lower end cap 32, and by heating the targeted drug, the targeted drug infused into the liver approaches the body temperature.

[0027] The present invention is not limited to the above-mentioned optimal implementation manner. Anyone should know that structural changes made under the inspiration of the present invention, as long as they have the same or similar technical solutions as the present invention, fall within the protection scope of the present invention. Finally, it should also be noted that the structures, proportions, sizes, etc. shown in the drawings of this specification are only used to cooperate with the content disclosed in the specification for those familiar with this technology to understand and read, and are not used to limit the implementable conditions of this application. Therefore, they do not have technical substantial significance. Any modification of the structure, change of the proportional relationship, or adjustment of the size, without affecting the efficacy that this application can produce and the purpose that can be achieved, should still fall within the scope that the technical content disclosed in this application can cover.

Claims

1. A liver tumor targeted radiotherapy catheter, comprising a catheter control handle (1), characterized in that: The front end of the catheter control handle (1) is provided with a catheter guiding mechanism (4), the side of the catheter control handle (1) is provided with a radiotherapy drug delivery mechanism (2), and the front end of the radiotherapy drug delivery mechanism (2) is provided with a drug heating mechanism (3); The catheter control handle (1) comprises a control handle (11), a data transmission line (12) fixedly connected to the left side of the control handle (11), and a control knob (13) arranged on the right side wall of the control handle (11); a catheter interface (14) is fixedly connected to the front side of the right side wall of the control handle (11); The radiotherapy drug delivery mechanism (2) comprises a handle (23), a trigger (22) movably arranged at the front side of the handle (23), and a connecting tube (21) fixed at the front end of the handle (23); a medicine tank connector (25) is arranged at the left side of the connecting tube (21); and a medicine tank (24) is screwedly connected to an end of the medicine tank connector (25) away from the connecting tube (21); The medicine temperature raising mechanism (3) comprises an upper end cover (31) and a lower end cover (32), a plurality of electric heating rods (34) are arranged between the upper end cover (31) and the lower end cover (32), the front end surfaces of the upper end cover (31) and the lower end cover (32) are fixedly connected with a catheter connecting nozzle (33), and the rear end surfaces of the upper end cover (31) and the lower end cover (32) are fixedly connected with a connecting nozzle (35); The catheter guiding mechanism (4) comprises an outer tube (41), a treatment catheter (42) enclosed in the inner cavity of the outer tube (41), the front end of the outer tube (41) is fixedly connected to an elliptical air bag (45), the front end of the elliptical air bag (45) is fixedly connected to an outer tube end (47), and the rear end of the elliptical air bag (45) is penetrated by a trachea (43).

2. The liver tumor targeted radiotherapy catheter according to claim 1, characterized in that: The interior of the control handle (11) and the interior of the catheter interface (14) are both provided with a chamber for the treatment catheter (42) to pass through, and the end of the treatment catheter (42) that passes through the interior of the catheter interface (14) is fixedly connected to an end of the catheter connection nozzle (33) that is away from the upper end cover (31) and the lower end cover (32).

3. The liver tumor targeted radiotherapy catheter according to claim 1, characterized in that: The front end surface of the control handle (11) is fixedly connected to the rear end surface of the outer tube (41), and the end of the data transmission line (12) away from the control handle (11) is connected to the targeted radiotherapy host.

4. The liver tumor targeted radiotherapy catheter according to claim 1, characterized in that: An end of the connecting pipe (21) away from the handle (23) is fixedly connected to an end of the nozzle (35) away from the upper end cover (31) and the lower end cover (32).

5. The liver tumor targeted radiotherapy catheter according to claim 1, characterized in that: A drainage tube penetrating into the interior of the medicine tank (24) is arranged inside the port of the medicine tank connector (25) away from the connecting tube (21), a thread is arranged on the inner surface of the medicine tank connector (25), and a thread matching the thread is arranged on the outer ring of the bottle mouth of the medicine tank (24), and the inner cavity of the medicine tank (24) is loaded with tumor-targeted radiotherapy drugs.

6. The liver tumor targeted radiotherapy catheter according to claim 1, characterized in that: The end surfaces of the upper end cover (31) and the lower end cover (32) that are close to each other are fixedly connected by a plurality of screws, a space for accommodating the electric heating rod (34) is formed between the upper end cover (31) and the lower end cover (32), and a gap for the circulation of medicine is provided between the inner cavity side walls of the upper end cover (31) and the lower end cover (32) and the outer surface of the electric heating rod (34).

7. The liver tumor targeted radiotherapy catheter according to claim 1, characterized in that: The interior of the catheter connection nozzle (33) is provided with a plurality of through holes for the circulation of drugs, and the interior of the connection nozzle (35) is provided with a plurality of through holes for the circulation of drugs.

8. The liver tumor targeted radiotherapy catheter according to claim 1, characterized in that: The front and rear ends of the electric heating rod (34) are respectively fixed to the end surfaces of the catheter connecting nozzle (33) and the connecting nozzle (35) on one side close to each other, and the power supply end of the electric heating rod (34) is connected to the electric wire that passes through the lower end cover (32), and the inner cavities of the lower end cover (32) and the upper end cover (31) are equipped with temperature sensors.

9. The liver tumor targeted radiotherapy catheter according to claim 1, characterized in that: The front end of the treatment catheter (42) passes through the front end port of the outer tube (41), and the end of the trachea (43) away from the elliptical air bag (45) is connected to a medical air pump.

10. The liver tumor targeted radiotherapy catheter according to claim 1, characterized in that: The oval air bag (45) has a catheter channel (44) for the treatment catheter (42) to pass through, and the oval air bag (45) has a chamber (46) for the air supply tube (43) to transport gas.

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