Paraffin section detection method fusing Masson and HE staining and application

Through the paraffin section detection method that combines Masson and HE staining, the problem of difficulty in performing HE and Masson staining on the same specimen in traditional methods is solved, and the multi-faceted observation of tissue specimens and the accuracy of disease diagnosis is achieved.

CN120142286APending Publication Date: 2025-06-13ZHEJIANG UNIV
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Patent Information

Application Number
CN202411645669.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-18
Publication Date
2025-06-13

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Abstract

The invention relates to a paraffin section detection method fusing Masson and HE dyeing and application, HE dyeing and Masson dyeing are carried out on the same specimen, and information of multiple aspects such as the basic structure of tissue cells, the dyeing condition of cell nucleuses and cytoplasm, the distribution condition of collagenous fibers and muscle fibers and the like can be obtained at the same time. Therefore, a more comprehensive and more accurate basis is provided for diagnosis and research of diseases. By adopting the method and the system, the diagnosis accuracy can be improved, more comprehensive and more accurate information is provided for disease research, and the occurrence mechanism, the development process and the treatment effect of the disease can be deeply known. The tedious process that different dyeing specimens need to be manufactured in a traditional method is avoided, and time and cost are saved. Meanwhile, continuous dyeing detection can be performed on the same specimen, so that the usage amount of the specimen is reduced, and the injury to a patient is reduced.
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