Chinese herbal plant combination and probiotic formula for efficiently conditioning qi stagnation and blood stasis of human body and dredging meridians

Through probiotic fermentation and enzymatic decomposition technology combined with Chinese herbal plant formula, the existing Chinese herbal products have been solved, the problems of low efficiency, slow efficacy and poor generality in treating Qi stagnation and blood stasis, and the effective, safe and good taste of Chinese herbal conditioning effect has been achieved.

CN120154686AInactive Publication Date: 2025-06-17SHENZHEN MR HANLU JILI CHILDRENS HEALTH SERVICE CO LTD
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Patent Information

Application Number
CN202510499642.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-21
Publication Date
2025-06-17
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The existing Chinese herbal medicine products are inefficient, slow, poor in efficacy, and have poor generality in treating Qi stagnation and blood stasis, and have a bitter taste and high toxicity.

Method used

Probiotic fermentation and enzymatic decomposition technology are used to combine Salvia miltiorrhiza, Rhodiola, Panax notoginseng, Asarum, Pueraria root, Gastrodia elata, Chuanxiong, Angelica sinensis and Astragalus to form an efficient medium herbal plant combination + probiotic formula to improve the efficacy and bioavailability through enzymatic decomposition.

Benefits of technology

It significantly improves the extraction rate and bioavailability of effective ingredients of Chinese herbal medicine, enhances the efficacy, improves the taste, reduces toxicity, and achieves conditioning effects in a short period of time.

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Abstract

The invention discloses a Chinese herbal plant composition and probiotic formula capable of efficiently conditioning qi stagnation and blood stasis of a human body and dredging channels. The Chinese herbal plant composition and probiotic formula comprises probiotics, salvia miltiorrhiza, rhodiola rosea, pseudo-ginseng, asarum, radix puerariae, gastrodia elata, ligusticum wallichii, angelica sinensis and astragalus membranaceus. Wherein the probiotics (30ml reference value) comprise 1g of salvia miltiorrhiza, 1g of rhodiola rosea, 1g of pseudo-ginseng, 1g of asarum, 1g of radix puerariae, 1g of gastrodia elata, 1g of ligusticum wallichii, 1g of angelica sinensis and 1g of astragalus membranaceus. Compared with the prior art, the traditional Chinese medicine composition has the advantages that the formula is derived from the corresponding biochemical effect in a human body according to the symbiotic and mutual-soluble principle of Chinese herbs, so that the conditioning effect is achieved. And the formula composed of Chinese herbs with corresponding effects improves the effects under the biochemical action of accelerating the corresponding effects by the probiotics, reduces the drug toxicity, and improves the bitter feeling of the drug.
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Description

Technical Field

[0001] The present invention relates to the technical field of Chinese herbal medicine powders, and specifically to a combination of Chinese herbal plants + probiotic formula that can effectively regulate qi stagnation and blood stasis in the human body and dredge the meridians. Background Art

[0002] Among the current middle-aged, young and elderly populations, the phenomena of qi stagnation and blood stasis and blocked meridians are relatively common. The main reasons include life stress, bad habits, lack of exercise and irregular diet, etc.

[0003] I. Common manifestations are as follows:

[0004] 1. Pain: Qi stagnation and blood stasis often cause local pain, such as headache, chest pain, joint pain, etc. The pain is mostly fixed and stabbing.

[0005] 2. Fatigue and weakness: Poor qi and blood circulation lead to insufficient energy supply, manifested as tiredness, weakness and listlessness.

[0006] 3. Mood swings: Qi stagnation is likely to cause mood problems, such as anxiety, depression, irritability, etc.

[0007] 4. Skin problems: Blood stasis may lead to dull skin, skin spots, dark circles under the eyes, etc.

[0008] 5. Digestive problems: Qi stagnation affects the functions of the spleen and stomach, resulting in abdominal distension, constipation or diarrhea.

[0009] 6. Irregular menstruation: Women may experience menstrual disorders, dysmenorrhea, blood clots in menstrual blood, etc.

[0010] II. Main reasons

[0011] 1. Life stress: Stress from work, family, etc. leads to emotional tension and affects the qi and blood circulation.

[0012] 2. Lack of exercise: Sitting still for a long time makes the qi and blood circulation worse and the meridians blocked.

[0013] 3. Irregular diet: High-fat, high-sugar and high-salt diets aggravate the stasis in the body.

[0014] 4. Lack of sleep: Staying up late for a long time affects the liver's detoxification function and leads to poor qi and blood circulation.

[0015] 5. Environmental factors: External evils such as air pollution and humid environment invade the body, aggravating qi and blood stasis.

[0016] III. Conditioning methods

[0017] 1. Exercise: Moderate exercise such as tai chi, yoga, walking, etc. can promote qi and blood circulation.

[0018] 2. Dietary conditioning: Eat more foods that promote blood circulation and remove blood stasis, such as hawthorn, black fungus, red dates, etc., and avoid raw, cold and greasy foods.

[0019] 3. Emotional management: Relieve stress and keep your emotions stable through meditation, deep breathing, etc.

[0020] 4. Traditional Chinese medicine conditioning: Acupuncture, massage, cupping, etc. help to dredge the meridians and improve the circulation of qi and blood.

[0021] 5. Get enough sleep: Ensure 7-8 hours of sleep to help the body repair itself.

[0022] The above conditioning methods have certain effects, and the effect varies from person to person. The present invention seeks a high-efficiency conditioning formula that can solve the basic problem of qi stagnation and blood stasis caused by people's long-term bad living habits from the inside of the body within a certain time limit, and is suitable for most middle-aged, young and elderly people to regularly regulate their bodies. Summary of the invention

[0023] The technical problem to be solved by the present invention is to overcome the technical defects of the Chinese herbal medicines currently on the market, such as incomplete efficacy, slow efficacy, strong pertinence, poor universality, toxicity and bitter taste.

[0024] In order to solve the above problems, the technical solution of the present invention is: a Chinese herbal plant combination + probiotic formula for effectively regulating qi stagnation and blood stasis in the human body and unblocking meridians, including probiotics, salvia miltiorrhiza, rhodiola rosea, Panax notoginseng, asarum, kudzu root, gastrodia elata, chuanxiong, angelica, and astragalus. People can regulate for two weeks every quarter and use it as a regular conditioning beverage.

[0025] The present invention is a novel Chinese herbal plant formula developed by utilizing a novel biotechnology of probiotic fermentation and enzymolysis to effectively improve the effectiveness and bioavailability of the Chinese herbal plant formula.

[0026] The probiotics, 1g of Salvia miltiorrhiza, 1g of Rhodiola rosea, 1g of Panax notoginseng, 1g of Asarum, 1g of Pueraria root, 1g of Gastrodia elata, 1g of Chuanxiong, 1g of Angelica sinensis and 1g of Astragalus membranaceus are included.

[0027] Probiotic fermentation: Probiotics (such as lactic acid bacteria, bifidobacteria, etc.) grow and multiply under suitable conditions, and metabolize to produce a variety of enzymes (such as cellulase, protease, amylase, etc.).

[0028] These enzymes can break down macromolecular substances (such as cellulose, protein, polysaccharides, etc.) in Chinese herbal medicines and release small molecular active ingredients.

[0029] Enzymatic hydrolysis of probiotics: The enzymatic hydrolysis process can destroy the cell wall structure of Chinese herbal medicines and promote the release of effective ingredients (such as flavonoids, saponins, polysaccharides, etc.).

[0030] At the same time, enzymatic hydrolysis can also convert certain ingredients into active substances that are more easily absorbed by the human body.

[0031] Synergistic effect:

[0032] The metabolites of probiotics (such as organic acids, antimicrobial peptides, etc.) interact with the components of Chinese herbal medicines, which may produce a synergistic effect, enhancing the efficacy or expanding the functions.

[0033] Technical advantages

[0034] Improve the extraction rate of active ingredients:

[0035] Through enzymatic hydrolysis, the active ingredients in Chinese herbal medicines are more easily released, and the extraction efficiency is significantly improved.

[0036] Enhance bioavailability:

[0037] The molecular weight of the components of Chinese herbal medicines after enzymatic hydrolysis is smaller, and they are more easily absorbed and utilized by the human body.

[0038] Improve the taste of Chinese herbal medicines:

[0039] The fermentation and enzymatic hydrolysis processes can degrade the bitter components in Chinese herbal medicines, improving their taste and palatability.

[0040] Produce new active substances:

[0041] The metabolism of probiotics may produce new active components, expanding the functionality of Chinese herbal medicines.

[0042] Green and environmentally friendly:

[0043] This technology does not require the use of chemical solvents and belongs to green biotechnology, which is friendly to the environment.

[0044] Salvia miltiorrhiza has cardiovascular protection, antioxidant and anti-inflammatory, neuroprotection, and the prevention and treatment of liver fibrosis effects, and can improve microcirculation: dilate the coronary artery, increase blood flow, relieve angina pectoris, scavenge free radicals: the antioxidant ability of salvianolic acid B is stronger than that of vitamin E, protect vascular endothelial cells, inhibit inflammatory reactions: reduce inflammatory factors (such as TNF-α) in atherosclerotic plaques, improve cerebral ischemia: animal experiments show that the extract of Salvia miltiorrhiza can reduce the area of cerebral infarction, promote nerve repair, and anti-liver fibrosis: inhibit the activation of hepatic stellate cells and reduce collagen deposition.

[0045] Rhodiola rosea can replenish qi and activate blood circulation, dredge meridians and relieve asthma, and is especially suitable for symptoms of qi deficiency and blood stasis, chest pain due to stagnation of qi and blood stasis, hemiplegia due to stroke, and qi deficiency of the spleen and lungs, fatigue and asthma;

[0046] The effects of Panax notoginseng powder include but are not limited to hemostasis, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain, and enhancing physical fitness;

[0047] Asarum powder has a central inhibitory effect, can sedate and relieve pain, at the same time, it can also regulate the body temperature center and play an antipyretic role. In addition, Asarum powder also has an anti-inflammatory effect, significantly inhibits joint swelling, and can reduce blood sugar;

[0048] Kudzu root powder can dilate blood vessels, lower blood pressure, improve blood circulation, help reduce blood lipids and the risk of cardiovascular diseases. At the same time, kudzu root powder also has a certain adjuvant effect on regulating blood sugar. For those who often drink alcohol, kudzu root powder can promote alcohol metabolism and reduce the burden on the liver;

[0049] Gastrodia elata powder can protect the brain, improve neurological deficits after cerebral ischemia, reduce the volume of cerebral infarction, lower the permeability of the blood-brain barrier, and lower blood pressure. The gastrodian polysaccharide component in Gastrodia elata powder can promote the production of endogenous vasodilator substances and inhibit their release, which helps lower blood pressure. It has a sedative and calming effect: the gastrodin in Gastrodia elata powder can promote the release of γ-aminobutyric acid in the brain, which helps relieve anxiety and tension, regulate the nervous system, help improve sleep quality, and relieve symptoms of insomnia and dreaminess;

[0050] Chuanxiong powder can warm and dredge blood vessels, activate blood circulation to remove stasis, promote qi circulation and relieve stagnation. It can be used to treat syndromes such as liver qi stagnation, heart meridian blood stasis, and chest pain. Chuanxiong powder is pungent, dispersing, warm and dredging, and is an important medicine for treating headache, especially suitable for symptoms of wind-cold headache and pain in the limbs and joints. Chuanxiong powder can promote facial blood circulation, strengthen facial nutrition, help eliminate acne, improve dull and rough skin, and has a certain antipruritic effect. Chuanxiong powder has obvious inhibitory effects on various bacteria such as Escherichia coli, Shigella dysenteriae, and Pseudomonas aeruginosa, and can be used for antibacterial and anti-inflammatory. Chuanxiong powder is often used to treat menstrual disorders in women, such as dysmenorrhea and decreased menstrual flow, etc., which helps restore normal menstruation. Components such as tetramethylpyrazine in Chuanxiong powder can assist in lowering blood pressure, increasing coronary blood flow, reducing coronary resistance, inhibiting thrombus formation and platelet aggregation. Chuanxiong powder can dilate cerebral blood vessels, increase cerebral blood flow, and improve immune function, which is beneficial to improving cerebral blood circulation.

[0051] The effects of Angelica sinensis

[0052] Angelica sinensis is a commonly used traditional Chinese medicine with multiple effects, mainly including the following aspects:

[0053] 1. Tonifying blood and promoting blood circulation

[0054] Angelica sinensis is a good medicine for tonifying blood and is often used to treat symptoms such as pale complexion, dizziness, and palpitations caused by blood deficiency. It can also promote blood circulation to remove stasis, improve blood circulation, and relieve pain caused by blood stasis, such as dysmenorrhea and traumatic injuries.

[0055] 2. Regulating menstruation and relieving pain

[0056] Angelica sinensis has significant effects on problems such as irregular menstruation, dysmenorrhea, and amenorrhea in women, can regulate the menstrual cycle, and relieve discomfort during menstruation.

[0057] 3. Moistening the intestines and relieving constipation

[0058] Angelica sinensis has a laxative effect and is suitable for constipation caused by intestinal dryness due to blood deficiency, especially suitable for the elderly and those with weak constitutions.

[0059] 4. Enhance immunity

[0060] The polysaccharide components in Angelica sinensis help enhance the immune system and improve the body's resistance.

[0061] 5. Anti-inflammatory and antibacterial

[0062] Angelica sinensis has certain anti-inflammatory and antibacterial effects and can be used to relieve inflammation and infections.

[0063] 6. Protect the cardiovascular system

[0064] Angelica sinensis can dilate blood vessels, improve microcirculation, help lower blood pressure, and protect cardiovascular health.

[0065] 7. Antioxidant

[0066] The antioxidant components in Angelica sinensis help delay aging and reduce damage to cells by free radicals.

[0067] The effects of Astragalus membranaceus Astragalus membranaceus is a common traditional Chinese medicine with various effects, mainly including the following aspects:

[0068] 1. Tonify qi and lift yang

[0069] Astragalus membranaceus is an excellent herb for tonifying qi, especially suitable for symptoms such as qi deficiency with fatigue, loss of appetite, and listlessness.

[0070] It also has an improving effect on rectal prolapse, uterine prolapse, etc. caused by qi sinking in the middle-jiao.

[0071] 2. Strengthen the exterior and stop sweating

[0072] Astragalus membranaceus can enhance the body's exterior defense ability and is suitable for people with spontaneous sweating due to deficiency of the exterior (easy sweating, afraid of wind).

[0073] It is often combined with Atractylodes macrocephala and Saposhnikovia divaricata to treat deficiency-induced common cold.

[0074] 3. Promote diuresis and reduce edema

[0075] Astragalus membranaceus has a diuretic effect and is suitable for symptoms such as edema and oliguria caused by qi deficiency.

[0076] It is often used in the treatment of edema in diseases such as chronic nephritis and heart failure.

[0077] 4. Support detoxification and promote granulation

[0078] Astragalus membranaceus can promote wound healing and is suitable for stubborn sores, ulcers, etc.

[0079] It is also used for postoperative recovery or people with low immunity.

[0080] 5. Enhance immunity

[0081] Astragalus membranaceus can enhance the body's immunity and disease resistance, and is suitable for those who are weak and prone to illness.

[0082] It is often used for the prevention of colds or the adjuvant treatment of chronic diseases.

[0083] 6. Protect the cardiovascular system

[0084] Astragalus membranaceus can dilate blood vessels and improve blood circulation, and is applicable to symptoms such as palpitation and shortness of breath.

[0085] It has a certain adjuvant effect on cardiovascular diseases such as hypertension and coronary heart disease.

[0086] 7. Anti-fatigue

[0087] Astragalus membranaceus can enhance physical strength and endurance, relieve fatigue, and is suitable for those who are chronically fatigued and physically overdrawn.

[0088] 8. Regulate blood sugar

[0089] Astragalus membranaceus has a certain regulatory effect on blood sugar and is suitable for the adjuvant treatment of diabetes patients.

[0090] The advantages of the present invention compared with the existing technology are as follows:

[0091] Danshen powder, Rhodiola rosea, Panax notoginseng powder, Asarum sieboldii powder, Pueraria lobata powder, Gastrodia elata powder, Ligusticum chuanxiong powder, Angelica sinensis, Astragalus membranaceus in the present invention are proportioned according to certain grams of the above-mentioned medicinal powders, and then mixed evenly with a certain amount of probiotics and taken together. This prescription is based on the principle of symbiosis and mutual dissolution of Chinese herbal plants and their corresponding biochemical effects in the human body, so as to achieve the conditioning effect. And the powder composed of Chinese herbal plants with corresponding effects can improve the effect under the acceleration of the corresponding biochemical effects of probiotics, while reducing the drug toxicity and improving the bitter taste of the drug. Detailed implementation method

[0092] In order to make the content of the present invention easier to be clearly understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention.

[0093] A Chinese herbal plant powder + probiotic formula for efficiently conditioning qi stagnation and blood stasis in the human body and dredging meridians, including Salvia miltiorrhiza, Rhodiola rosea, Panax notoginseng, Asarum sieboldii, Pueraria lobata, Gastrodia elata, Ligusticum chuanxiong, Angelica sinensis and Astragalus membranaceus + probiotics, wherein 1 g of Salvia miltiorrhiza, 1 g of Rhodiola rosea, 1 g of Panax notoginseng, 1 g of Asarum sieboldii, 1 g of Pueraria lobata, 1 g of Gastrodia elata, 1 g of Ligusticum chuanxiong, 1 g of Angelica sinensis and 1 g of Astragalus membranaceus, and probiotics (reference value of 30 ml) are based on the above-mentioned formula. The conditioning period is two weeks, once every quarter.

[0094] In specific use, generally, it takes two weeks to show effects for conditioning. As general conditioning, it is recommended to conduct conditioning once every quarter. Mix the above formula according to the stated ratio to obtain the formula. Based on the principle of symbiotic mutual solubility of Chinese herbal plants, corresponding biochemical effects occur in the human body, thus achieving the conditioning effect. And the powder composed of Chinese herbal plants with corresponding effects can enhance the effect by 5 to 30 times under the acceleration of the corresponding biochemical effects of probiotics.

[0095] The above has described the present invention and its implementation manners. This description is not restrictive. Generally speaking, if those of ordinary skill in the art are inspired by it and, without departing from the purpose of the present invention, design similar structural manners and embodiments to this technical solution without creative efforts, they shall fall within the protection scope of the present invention.

Claims

1. A Chinese herbal plant combination + probiotic formula that can effectively regulate qi stagnation and blood stasis in the human body and dredge the meridians, characterized by: Including probiotics, Danshen, Rhodiola, Panax notoginseng, Asarum, Pueraria, Gastrodia, Chuanxiong, Chinese Angelica and Astragalus; The probiotics (30 ml reference value 1), salvia miltiorrhiza 1g, rhodiola rosea 1g, Panax notoginseng 1g, asarum 1g, kudzu root 1g, gastrodia 1g, ligusticum chuanxiong 1g, angelica 1g and astragalus 1g.

2. The Chinese herbal plant combination + probiotic formula for effectively regulating qi stagnation and blood stasis in the human body and unblocking meridians according to claim 1, characterized in that: According to the general price of conditioning, it is recommended to have a conditioning cycle of one week, once a quarter.