Human body microcirculation change monitoring method and device

Abstract

The invention relates to the technical field of medical detection, and particularly discloses a human body microcirculation change monitoring method and device.The human body microcirculation change monitoring method comprises the steps that the body surface skin temperature of a specific limb of a patient and the intracavity temperature of the patient are monitored; when the first difference value between the intracavity temperature and the body surface skin temperature is larger than a third threshold value, it is judged that microcirculation insufficiency occurs at the specific limbs of the patient. Monitoring the change condition of the first difference value in a third preset time period; when the first difference value is gradually reduced in a third preset time period, judging that the microcirculation blood flow of the patient enters a recovery state; and when the first difference value is gradually increased in a third preset time period, judging that the microcirculation blood flow of the patient enters a deterioration state. The microcirculation change of the patient is evaluated based on the body surface skin temperature, the intracavity temperature and other information of the specific limbs of the patient, non-invasive monitoring on the microcirculation change of the patient can be achieved, and then early warning analysis on the illness state of the patient can be achieved according to the microcirculation change condition of the patient.

Description

[0001] This application is a divisional application of the Chinese application with application number 2025101708720, application date February 17, 2025, and invention name “Method and device for monitoring changes in human microcirculation”. Technical Field

[0002] The present invention relates to the field of medical detection technology, and in particular to a method and device for monitoring changes in human microcirculation. Background Art

[0003] Shock refers to an acute systemic critical pathological process in which the effective circulating blood volume decreases sharply and the tissue blood perfusion volume is seriously insufficient under the influence of strong pathogenic factors such as severe blood loss, fluid loss, infection, and trauma, causing cell ischemia and hypoxia, resulting in functional and metabolic disorders and structural damage to important organs. A large number of studies have confirmed that shock is closely related to changes in microcirculation. Shock has different clinical manifestations at different stages, including microcirculatory spasm, microcirculatory stasis, and microcirculatory failure. A few hours before the patient's macrocirculatory physiological indicators (such as cardiac output, oxygen delivery, systemic blood flow, perfusion pressure, etc.) change, there is usually a decrease in microcirculatory blood flow, resulting in insufficient blood flow to the limbs, cold hands and feet, etc. When the patient's macrocirculatory physiological indicators drop sharply, the microcirculatory disorder usually enters the microcirculatory failure stage, and serious complications such as systemic organ failure occur frequently, which are difficult to treat and threaten life at any time.

[0004] The applicant noted that the "Apparatus and method for assessing the condition of critically ill patients" (US Pat. No. US4306569A) invented by MAX H.WEIL et al. discloses a method and device for assessing the condition of patients with circulatory shock by measuring the patient's peripheral or skin temperature. In the technical solution of this patent, the difference between the patient's toe temperature and the ambient temperature is measured. Specifically, the gradient of the difference between the toe temperature and the ambient temperature is calculated. If the difference between the toe temperature and the ambient temperature does not rise by at least a predetermined value (such as 3°C) within a predetermined time (such as ten hours), an indication of the patient's poor condition is given. The applicant noted that in this patent, the condition is assessed only by the difference between the patient's toe and the ambient temperature and its rate of change (gradient). Such an indicator is single. If the ambient temperature of the patient changes rapidly (such as changes in the temperature control of the air conditioning system, changes in the weather, and the patient is transferred to another place), the system will misjudge the patient's condition. Therefore, it is necessary to provide a method and device for monitoring changes in human microcirculation that can identify microcirculatory disorders as early as possible, and such a device can eliminate the interference of rapid changes in ambient temperature on the monitoring results as much as possible. Summary of the invention

[0005] Based on this, it is necessary to provide a monitoring method and device for human microcirculation changes that can identify microcirculation disorders as early as possible, and such a device can eliminate the interference of rapid changes in ambient temperature on monitoring results as much as possible. A monitoring method for human microcirculation changes, including selecting a first judgment mode as a microcirculation judgment mode in response to a start instruction; in the first judgment mode, monitoring the ambient temperature, the surface skin temperature of a patient's specific limb, and the intracavitary temperature of the patient; determining the microcirculation state of the patient according to the surface skin temperature and the intracavitary temperature; in response to the judgment result that the ambient temperature meets the first switching condition, switching the microcirculation judgment mode to a second judgment mode; in the second judgment mode, monitoring the ambient temperature and the surface skin temperature of the patient's specific limb; determining the microcirculation state of the patient according to the surface skin temperature and the ideal surface skin temperature corresponding to the ambient temperature; in response to the judgment result that the ambient temperature meets the second switching condition, switching to the first judgment mode.

[0006] The above-mentioned method for monitoring changes in human microcirculation enters the first judgment mode after receiving the start instruction. In the first judgment mode, the ambient temperature, the surface skin temperature of the patient's specific limbs and the patient's intracavitary temperature are monitored in real time, and the patient's microcirculation state is determined according to the surface skin temperature and the intracavitary temperature. When the ambient temperature meets the first switching condition, it switches to the second judgment mode. In the second judgment mode, the ambient temperature and the surface skin temperature of the patient's specific limbs are monitored in real time, and the patient's microcirculation state is determined according to the ideal surface skin temperature corresponding to the surface skin temperature and the ambient temperature. When the ambient temperature meets the second switching condition, it switches to the first judgment mode. Based on the information such as the surface skin temperature of the patient's specific limbs and the patient's intracavitary temperature, the changes in the patient's microcirculation are evaluated, and non-invasive monitoring of the patient's microcirculation changes can be achieved, and then the early warning analysis of the patient's condition can be achieved according to the changes in the patient's microcirculation. Selecting the first judgment mode or the second judgment mode as the microcirculation judgment mode based on the ambient temperature can reduce the influence of the ambient temperature on the evaluation results of the patient's microcirculation state, and improve the accuracy of the evaluation results of the patient's microcirculation state.

[0007] In one of the embodiments, the first switching condition is that a first change value of the ambient temperature within a first preset time period is greater than or equal to a first threshold.

[0008] In one of the embodiments, the second switching condition is that a second change value of the ambient temperature within a second preset time period is less than a second threshold value.

[0009] In one embodiment, determining the microcirculation state of the patient according to the surface skin temperature and the intracavitary temperature includes, when the surface skin temperature is less than the intracavitary temperature and a first difference between the intracavitary temperature and the surface skin temperature is greater than a third threshold, determining that microcirculation insufficiency occurs at a specific limb of the patient.

[0010] In one embodiment, after determining that the patient has microcirculation insufficiency, the method further includes monitoring a change in the first difference within a third preset time period; when the first difference gradually decreases within the third preset time period, determining that the microcirculation blood flow of the patient enters a recovery state; when the first difference gradually increases within the third preset time period, determining that the microcirculation blood flow of the patient enters a deterioration state.

[0011] In one embodiment, determining the microcirculation state of the patient according to the surface skin temperature and the ideal surface skin temperature corresponding to the environmental temperature includes determining an ideal surface skin temperature corresponding to the current environmental temperature according to a correspondence relationship between the environmental temperature and the ideal surface skin temperature at a specific limb; when the surface skin temperature is less than the ideal surface skin temperature and a second difference between the ideal surface skin temperature and the surface skin temperature is greater than a fourth threshold, determining that the patient has microcirculation insufficiency. In one embodiment, after determining that the patient has microcirculation insufficiency, the method further includes monitoring a change in the second difference within a fourth preset time period; when the second difference gradually decreases within the fourth preset time period, determining that the microcirculation blood flow of the patient enters a recovery state; when the second difference gradually increases within the fourth preset time period, determining that the microcirculation blood flow of the patient enters a deterioration state.

[0012] A monitoring device for human microcirculation changes, comprising a body surface temperature monitoring module for monitoring the body surface skin temperature at a specific limb of a patient; a cavity temperature monitoring module for monitoring the cavity temperature of the patient; an environmental temperature monitoring module for monitoring the environmental temperature; and a control module respectively connected to the body surface temperature monitoring module, the cavity temperature monitoring module and the environmental temperature monitoring module, configured to select a first judgment mode as the microcirculation judgment mode in response to a start instruction; in the first judgment mode, monitor the environmental temperature, the body surface skin temperature at a specific limb of the patient and the cavity temperature of the patient; determine the microcirculation state of the patient according to the body surface skin temperature and the cavity temperature; switch the microcirculation judgment mode to a second judgment mode in response to a judgment result that the environmental temperature meets a first switching condition; in the second judgment mode, monitor the environmental temperature and the body surface skin temperature at a specific limb of the patient; determine the microcirculation state of the patient according to the body surface skin temperature and the ideal body surface skin temperature corresponding to the environmental temperature; and switch to the first judgment mode in response to a judgment result that the environmental temperature meets a second switching condition.

[0013] In one embodiment, the body surface temperature monitoring module includes one or more skin temperature sensors, and the skin temperature sensors are fixed at the specific limb of the patient through heat insulation protection materials.

[0014] In one embodiment, when the specific limb of the patient is the toes of the patient's feet, the body surface temperature monitoring module determines the highest value of the toe temperature collected as the body surface skin temperature.

[0015] In one embodiment, the monitoring device for human microcirculation changes further includes a display module connected to the control module for displaying the environmental temperature, the body surface skin temperature at a specific limb of the patient and the cavity temperature of the patient; the control module is further configured to output different control signals according to different microcirculation states of the patient, and the display module is further configured to display a warning message according to the control signal. Description of the Drawings

[0016] In order to more clearly illustrate the embodiments of the present specification or the technical solutions in the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings described below are only some embodiments recorded in the present specification. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0017] Figure 1 It is a schematic flow chart of a monitoring method for human microcirculation changes in one embodiment of the present application;

[0018] Figure 2 Schematic diagram of the continuous trend change curve of the ambient temperature in one embodiment of the present application;

[0019] Figure 3 Schematic diagram of the method flow for determining the microcirculation state of a patient in the first judgment mode in one embodiment of the present application;

[0020] Figure 4 Schematic diagram of the continuous trend change curve of the intracavitary temperature and the toe temperature in one embodiment of the present application;

[0021] Figure 5 Schematic diagram of the method flow for determining the microcirculation state of a patient in the second judgment mode in one embodiment of the present application;

[0022] Figure 6 Schematic diagram of the comparison table of the ambient temperature - ideal body surface skin temperature in one embodiment of the present application;

[0023] Figure 7 Schematic diagram of the continuous trend change curve of the intracavitary temperature and the toe temperature in one embodiment of the present application;

[0024] Figure 8 Schematic diagram of the structure of the monitoring device for human microcirculation changes in one embodiment of the present application. Detailed implementation manners

[0025] To facilitate the understanding of the present invention, the present invention will be described more comprehensively below with reference to the relevant drawings. The preferred embodiments of the present invention are given in the drawings. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to understand the disclosure of the present invention more thoroughly and comprehensively.

[0026] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the technical field to which the present invention belongs. The terms used in the specification of the present invention herein are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more of the related listed items.

[0027] A monitoring method for human microcirculation changes provided by the present application can non-invasively monitor the microcirculation changes of a patient, and further can warn of the deterioration of shock according to the microcirculation changes of the patient, facilitating early intervention by medical staff for the patient.

[0028] In some embodiments, the method for monitoring changes in human microcirculation can be executed by a control module in a monitoring device for changes in human microcirculation. For example, the method for monitoring changes in human microcirculation can be stored in the control module in the form of a program or instructions, and when the program or instructions are executed, the method for monitoring changes in human microcirculation can be implemented. The device for implementing the method for monitoring changes in human microcirculation disclosed in this application can be either a device with a large amount of computing resources (such as a computer, a server, cloud computing, etc.) or a device with limited computing resources (such as a hardware circuit like an FPGA chip board or an ASIC chip board).

[0029] Figure 1 FIG. 4 is a schematic flowchart of the method for monitoring changes in human microcirculation in one embodiment of this application. In one embodiment, the method for monitoring changes in human microcirculation can include the following steps S100 to step S700.

[0030] Step S100: In response to a start instruction, select the first judgment mode as the microcirculation judgment mode.

[0031] Since the skin temperature on the patient's body surface is often greatly affected by the environmental temperature, when judging the patient's microcirculation state based on the patient's body temperature, by designing different microcirculation judgment modes, different judgment modes are used to determine the patient's microcirculation state under different environmental conditions to reduce the influence of the environmental temperature on the judgment accuracy rate. In the embodiments of this application, the microcirculation judgment mode can include a first judgment mode and a second judgment mode, that is, based on the environmental temperature, it is determined whether to use the first judgment mode or the second judgment mode to judge the patient's microcirculation state.

[0032] Under normal circumstances, the environmental temperature where the patient is located is stable (such as in-hospital monitoring or on-site first aid monitoring). Therefore, in this embodiment, the first judgment mode can be used as the default mode, that is, after receiving the start instruction and starting the microcirculation monitoring for the patient, the first judgment mode is default selected to judge the patient's microcirculation state.

[0033] Step S200: Under the first judgment mode, monitor the environmental temperature, the skin temperature on the patient's specific limb, and the patient's cavity temperature.

[0034] The environmental temperature is a physical quantity used to represent the hot or cold degree of the environment where the patient is located. The monitoring device for changes in human microcirculation can be provided with an environmental temperature monitoring module, and the environmental temperature monitoring module is used to monitor the environmental temperature in real time.

[0035] Considering that when the microcirculation blood flow of a patient decreases, the hands and feet are prone to hypothermia due to insufficient blood flow in the limbs. Therefore, in the embodiments of the present application, the specific limb of the patient may refer to the limb positions of the patient, such as fingers, toes, and the brain. Since the toes are the farthest extremities from the heart in the human body, it is more accurate to monitor the microcirculation state of the patient based on the skin temperature of the toe surface. In a preferred embodiment, the specific limb of the patient refers to the toes. The monitoring device for human microcirculation changes may also be provided with a body surface temperature monitoring module to monitor the skin temperature of the specific limb of the patient in real time using the body surface temperature monitoring module.

[0036] The temperature inside the human body can be called the intracavitary temperature, and the intracavitary temperature is also an important medical vital sign, which often changes continuously with the patient's physical condition. The monitoring device for human microcirculation changes may also be provided with an intracavitary temperature monitoring module to achieve non-invasive monitoring of the patient's intracavitary temperature by measuring the temperatures at the eardrum, oral cavity, esophagus, rectum, bladder, etc. using the intracavitary temperature monitoring module. In a preferred embodiment, the intracavitary temperature of the patient is measured through the rectum.

[0037] Step S300: Determine the microcirculation state of the patient based on the skin temperature of the body surface and the intracavitary temperature.

[0038] When it is determined according to the environmental temperature that the first judgment mode is adopted, the microcirculation state of the patient can be determined based on the skin temperature of the body surface and the intracavitary temperature of the patient. In a feasible implementation manner, when the temperature in the environment where the patient is located is in a relatively constant state, the changes in the skin temperature of the patient's body surface are mainly affected by the patient's condition changes. Therefore, the current microcirculation state of the patient can be judged based on the skin temperature of the patient's body surface and the intracavitary temperature.

[0039] Step S400: In response to the judgment result that the environmental temperature meets the first switching condition, switch the microcirculation judgment mode to the second judgment mode.

[0040] Considering that in actual patient monitoring, there may be situations where the patient is transferred, or the temperature of the patient's environment changes significantly. For example, the patient is transferred from the emergency scene to the hospital by ambulance, or from Hospital A to Hospital B. Generally, the limb temperature of the human body is greatly affected by environmental changes, while the internal cavity temperature of the human body changes less with the environment. Therefore, when the environmental temperature changes greatly, if the change trend of the difference between the skin temperature of a specific limb position (such as toes) of the patient and the internal cavity temperature of the patient is still compared, it may lead to inaccurate judgment of the patient's microcirculation changes and incorrect conclusions. Therefore, when the environmental temperature changes greatly, the second judgment mode is used to determine the patient's microcirculation state, that is, the current microcirculation state of the patient is judged according to the skin temperature of the specific limb position of the patient and the ideal skin temperature of the human body at the current environmental temperature.

[0041] While monitoring the patient's microcirculation state using the first judgment mode, the environmental temperature can also be monitored in real time. By judging whether the environmental temperature meets the first switching condition, it can be determined whether there is a large temperature change in the current environmental temperature. When the environmental temperature meets the first switching condition, it can be judged that there is a large temperature change in the current environmental temperature. In this case, the microcirculation judgment mode can be switched to the second judgment mode, and the second judgment mode is used to monitor the patient's microcirculation state under the condition of large environmental temperature changes. In practical applications, different first switching conditions can be designed according to different application scenarios. For example, the temperature change value of the environmental temperature within a fixed time exceeds a certain threshold, or the change rate of the environmental temperature exceeds a certain threshold.

[0042] Step S500: In the second judgment mode, monitor the environmental temperature and the skin temperature of the specific limb of the patient.

[0043] In the second judgment mode, the environmental temperature monitoring module is used to monitor the environmental temperature in real time, and the body surface temperature monitoring module is used to monitor the skin temperature of the specific limb of the patient in real time.

[0044] Step S600: Determine the patient's microcirculation state according to the skin temperature and the ideal skin temperature corresponding to the environmental temperature.

[0045] When it is determined to adopt the second judgment mode according to the ambient temperature, the microcirculation state of the patient can be determined based on the skin surface temperature of the body and the ideal skin surface temperature corresponding to the ambient temperature. In a feasible implementation manner, when the temperature in the environment where the patient is located changes greatly, the change in the skin surface temperature of the patient is affected not only by the change in the patient's condition, but also may be affected by the ambient temperature. Therefore, when the ambient temperature changes greatly, the ideal skin surface temperature of the patient at this ambient temperature can be determined according to the ambient temperature, and then the current microcirculation state of the patient can be judged based on the actual skin surface temperature and the ideal skin surface temperature of the patient.

[0046] Step S700: In response to the judgment result that the ambient temperature meets the second switching condition, switch to the first judgment mode.

[0047] Considering that in the actual monitoring of patients, after the ambient temperature changes, such as when the patient is transferred, it is also possible that the environment where the patient is located becomes stable. And it is more accurate to use the first judgment mode to determine the microcirculation state of the patient when the ambient temperature is stable. Therefore, in the case of switching to the second judgment mode, it is also possible to continue to continuously monitor the change of the ambient temperature to judge whether the ambient temperature has returned to a stable state, so as to judge whether it is necessary to switch to the first judgment mode to determine the current microcirculation state of the patient.

[0048] In this embodiment, it is possible to judge whether the current ambient temperature is stable by judging whether the ambient temperature meets the second switching condition. When the ambient temperature meets the second switching condition, it can be judged that the current ambient temperature is in a stable state. In this case, the microcirculation judgment mode can be switched to the first judgment mode, and the first judgment mode is used to realize the monitoring of the microcirculation state of the patient in the case of large ambient temperature changes.

[0049] In practical applications, different second switching conditions can be designed according to different application scenarios. For example, the temperature change value of the ambient temperature within a fixed time is less than a certain threshold, or the change rate of the ambient temperature is less than a certain threshold.

[0050] The monitoring method for human microcirculation changes provided by this application enters the first judgment mode after receiving a start instruction. In the first judgment mode, the environmental temperature, the skin temperature of the specific limb of the patient, and the cavity temperature of the patient are monitored in real time, and the microcirculation state of the patient is determined based on the skin temperature and the cavity temperature. When the environmental temperature meets the first switching condition, it switches to the second judgment mode. In the second judgment mode, the environmental temperature and the skin temperature of the specific limb of the patient are monitored in real time, and the microcirculation state of the patient is determined based on the skin temperature and the ideal skin temperature corresponding to the environmental temperature. When the environmental temperature meets the second switching condition, it switches back to the first judgment mode. Evaluating the microcirculation changes of the patient based on information such as the skin temperature of the specific limb of the patient and the cavity temperature of the patient can achieve non-invasive monitoring of the microcirculation changes of the patient, help identify microcirculation abnormalities of the patient earlier, and realize early warning analysis of the patient's condition, which is crucial for medical staff to intervene in the deterioration of the patient's condition in a timely manner. Selecting the first judgment mode or the second judgment mode as the microcirculation judgment mode based on the environmental temperature can reduce the influence of the environmental temperature on the evaluation result of the patient's microcirculation state and improve the accuracy of the evaluation result of the patient's microcirculation state.

[0051] In one embodiment, the first switching condition may be that the first change value of the environmental temperature within the first preset time period is greater than or equal to the first threshold. Specifically, when working in the first judgment mode, the first change value of the environmental temperature within the first preset time period is continuously monitored.

[0052] The environmental temperature monitoring module continuously monitors the temperature of the environment where the patient is located. The environmental temperature monitoring module can also generate a continuous trend change curve of the environmental temperature based on the monitoring data, and the change situation of the environmental temperature can be more intuitively understood based on the continuous trend change curve of the environmental temperature. In this embodiment, the first change value may refer to the absolute value of the difference between the environmental temperatures at different times. For example, when the first preset time period is 1 hour, the absolute value of the difference between the current environmental temperature and the environmental temperature 1 hour ago can be calculated to determine the first change value.

[0053] When the first change value is greater than or equal to the first threshold, it can be determined that the first switching condition is met, and the microcirculation judgment mode is switched from the first judgment mode to the second judgment mode, that is, the second judgment mode is used to determine the microcirculation state of the patient. When the first change value is greater than or equal to the first threshold, it indicates that the temperature change in the environment where the patient is located is relatively large. In this case, the change in the skin temperature of the patient is not only affected by the change in the patient's condition, but may also be affected by the change in the environmental temperature. Therefore, the second judgment mode can be used to determine the microcirculation state of the patient.

[0054] The monitoring method for human microcirculation changes provided by this application is based on different ambient temperature change situations, and different microcirculation judgment modes are selected to determine the microcirculation state of the patient, which can reduce the influence of ambient temperature on the judgment result and improve the judgment accuracy.

[0055] In one embodiment, when the first change value is less than the first threshold, the first judgment mode is continued to determine the microcirculation state of the patient. When the first change value is less than the first threshold, it indicates that the temperature change in the environment where the patient is located is small. In this case, the change in the skin temperature of the patient's body surface is mainly affected by the change in the patient's condition. Therefore, the first judgment mode can be continued to determine the microcirculation state of the patient. In this embodiment, the first threshold can be reasonably set according to actual application requirements. Preferably, the first threshold can be a value greater than zero. For example, when the first preset time period is 1 hour and the first threshold is set to 3 °C, when it is detected that the first change value of the ambient temperature within 1 hour is less than 3 °C (that is, the value of the increase or decrease of the ambient temperature within 1 hour is less than 3 °C), it is determined to use the first judgment mode to determine the microcirculation state of the patient.

[0056] In one embodiment, the second switching condition can be that the second change value of the ambient temperature within the second preset time period is less than the second threshold. Specifically, when working in the second judgment mode, the second change value of the ambient temperature within the second preset time period is continuously monitored.

[0057] The ambient temperature monitoring module is used to continuously monitor the temperature of the environment where the patient is located. In this embodiment, the second change value can also refer to the absolute value of the difference between the ambient temperatures at different times. For example, when the second preset time period is 0.5 hour, the absolute value of the difference between the current ambient temperature and the ambient temperature 0.5 hour ago can be calculated to determine the second change value.

[0058] When the second change value is less than the second threshold, it can be determined that the second switching condition is met, and the microcirculation judgment mode is switched from the second judgment mode to the first judgment mode, that is, the first judgment mode is used to determine the microcirculation state of the patient.

[0059] When the second change value is less than the fourth threshold, it indicates that the temperature change in the environment where the patient is located is small, that is, the ambient temperature tends to be stable. In this case, it is more accurate to use the first judgment mode to determine the microcirculation state of the patient. Therefore, when the second change value is less than the second threshold, the microcirculation state of the patient can be determined according to the relationship between the skin temperature of the patient's specific limb position (such as toes) and the patient's cavity temperature.

[0060] In this embodiment, the second threshold can be reasonably set according to actual application requirements. Preferably, the second threshold can be a value greater than zero. For example, when the second preset time period is 2 hours and the second threshold is set to 0.2 °C, after using the second judgment mode, when it is detected that the value of the environmental temperature increase or decrease within 2 hours is less than 0.2 °C, it is determined that the environmental temperature tends to be stable, and it is determined to switch to the first judgment mode to determine the current microcirculation state of the patient.

[0061] In one embodiment, when the second change value is greater than or equal to the fourth threshold, the second judgment mode can continue to be used to determine the microcirculation state of the patient. When the second change value is greater than or equal to the second threshold, it indicates that the temperature change in the environment where the patient is located is still relatively large. Therefore, in this case, it is more accurate to continue to use the second judgment mode to determine the microcirculation state of the patient. That is, the microcirculation state of the patient is determined according to the relationship between the actual body surface skin temperature at a specific limb position of the patient and the ideal body surface skin temperature under the current environmental temperature.

[0062] Figure 2 FIG. is a schematic diagram of the continuous trend change curve of the environmental temperature in one embodiment of the present application. In this embodiment, Figure 2 Taking the shown environmental temperature change situation as an example to illustrate the switching situation of the microcirculation judgment mode in the present application, the description is relatively specific and detailed, but it should not be construed as a limitation on the scope of the invention patent.

[0063] After receiving the start instruction and starting the microcirculation monitoring for the patient, the first judgment mode is default selected to judge the microcirculation state of the patient. At the same time, the temperature change of the environmental temperature is monitored in real time, and it is judged whether to switch the judgment mode by comparing the first change value of the environmental temperature in the first preset time with the first threshold. As Figure 2 shown, before time t2, the first change value of the environmental temperature within the first preset time period is less than the first threshold, so the first judgment mode is maintained to judge the microcirculation state of the patient in the first time period T1. Since the first change value between the environmental temperature at time t2 and the environmental temperature at time t1 is greater than or equal to the first threshold, and the time difference between time t2 and time t1 is the first preset time period, therefore, at time t2, the microcirculation judgment mode is switched from the first judgment mode to the second judgment mode.

[0064] Similarly, the temperature change of the environmental temperature is monitored in real time, and it is judged whether to switch the judgment mode by comparing the second change value of the environmental temperature in the second preset time with the second threshold. As Figure 2Among them, between time t2 and time t4, the second change value of the ambient temperature within the second preset time period is greater than or equal to the second threshold. Therefore, in the second time period T2, the second judgment mode is continuously used to judge the microcirculation state of the patient. Since the second change value between the ambient temperature at time t4 and the ambient temperature at time t3 is less than the second threshold, and the time difference between time t4 and time t3 is the second preset time period, therefore, at time t4, the microcirculation judgment mode is switched from the second judgment mode to the first judgment mode. The third time period T3 starting from time t4 uses the first judgment mode to judge the microcirculation state of the patient.

[0065] Figure 3 This is a schematic flowchart of a method for determining the microcirculation state of a patient in the first judgment mode in one embodiment of the present application. In one embodiment, in the first judgment mode, determining the microcirculation state of the patient based on the body surface skin temperature and the intracavity temperature may include the following step S310.

[0066] Step S310: When the body surface skin temperature is less than the intracavity temperature, and the first difference between the intracavity temperature and the body surface skin temperature is greater than the third threshold, it is determined that microcirculation insufficiency occurs at a specific limb of the patient.

[0067] Continuously monitor the body surface skin temperature at a specific limb of the patient and the intracavity temperature of the patient, and compare the body surface skin temperature and the intracavity temperature. When the body surface skin temperature at a specific limb position (such as the toe) of the patient is less than the intracavity temperature, and the first difference between the intracavity temperature and the body surface skin temperature is greater than the third threshold, it indicates that the body temperature at the specific limb position of the patient has dropped. Therefore, it can be determined that microcirculation insufficiency occurs at the specific limb position of the patient at this time. It should be noted that in the present application, the first difference refers to the difference between the intracavity temperature minus the body surface skin temperature. Since the body surface skin temperature is less than the intracavity temperature at this time, the first difference is a positive number. The third threshold can be reasonably set according to actual application requirements. Preferably, the third threshold can be a value greater than zero.

[0068] In the monitoring method for human microcirculation changes provided by the present application, in the first judgment mode, based on the relationship between the body surface skin temperature at a specific limb position of the patient and the intracavity temperature of the patient to judge whether the patient has microcirculation insufficiency problems, avoiding using the ambient temperature as a reference for judgment, can avoid the interference of external temperature fluctuations on the judgment result, and thus can more accurately reflect the microcirculation state of the patient.

[0069] In one embodiment, after determining that microcirculation insufficiency occurs at a specific limb of the patient, a warning message of microcirculation insufficiency can also be generated. Using the warning message to warn of the deterioration of the patient's shock condition, so that medical staff can intervene in the patient's condition earlier.

[0070] In one embodiment, please refer to Figure 3 , after it is determined that the patient has insufficient microcirculation, the method may further include the following steps S320 to S340.

[0071] Step S320: Monitor the change of the first difference within a third preset time period.

[0072] In the case of determining that the patient has insufficient microcirculation, it is also possible to further analyze whether the patient's microcirculation is in a recovery state or a deteriorating state based on the changes in the surface skin temperature and the intraluminal temperature at a specific limb position of the patient, and then the feasibility of the patient's shock resuscitation can be estimated based on the changes in the patient's microcirculation. Step S330: When the first difference gradually decreases within the third preset time period, it is determined that the microcirculation blood flow of the patient enters the recovery state.

[0073] Step S340: When the first difference gradually increases within the third preset time period, it is determined that the microcirculation blood flow of the patient enters the deteriorating state.

[0074] Generally, microcirculation monitoring is carried out for critically ill patients who are about to go into shock. At this time, it is defaulted that the intraluminal temperature of the patient is in a normal state. Generally, when the environmental temperature is stable, the intraluminal temperature of the patient does not change much. When there is a significant change in the intraluminal temperature of the patient, an alarm can be directly given for this situation. In the embodiment of the present application, the first judgment mode is adopted to determine the microcirculation state of the patient when the environmental temperature is relatively stable. Continuously monitor the change trend of the first difference between the intraluminal temperature and the surface skin temperature at a specific limb of the patient. It is also possible to generate a continuous trend change curve of the first difference based on the change of the first difference. Based on the continuous trend change curve of the first difference, the change of the first difference can be intuitively understood. Since the intraluminal temperature of the patient does not change much when the environmental temperature is stable, the change of the first difference is mainly affected by the temperature change at a specific limb of the patient. When the first difference shows a gradually decreasing change trend within the second preset time period, it indicates that the temperature at a specific limb of the patient has risen, so it can be determined that the microcirculation blood flow at a specific limb of the patient has entered the recovery state. When the first difference shows a gradually increasing change trend within the second preset time period, it indicates that the temperature at a specific limb of the patient has further decreased, so it can be determined that the microcirculation blood flow at a specific limb of the patient has entered the deteriorating state.

[0075] Figure 4 FIG. is a schematic diagram of the continuous trend change curve of the intraluminal temperature and the toe temperature in one embodiment of the present application. In this embodiment, Figure 4Taking the changes in the intracavity temperature and toe temperature shown as an example, the first judgment mode adopted in this application to judge the microcirculation state at a specific limb of a patient is described in detail and specifically, but it should not be construed as a limitation on the scope of the invention patent for this reason.

[0076] When determining the microcirculation state of a patient using the first judgment mode, at time t5, the toe temperature of the patient is lower than the intracavity temperature, and the first difference between the intracavity temperature and the toe temperature is greater than the third threshold. Therefore, it can be judged that the patient has insufficient microcirculation at the toes starting from time t5. When it is judged that the patient has insufficient microcirculation, the change in the first difference between the intracavity temperature and the toe temperature is continuously monitored. When it is monitored that the first difference gradually increases during the third preset time period between time t5 and time t6, it can be judged at this time that the microcirculation blood flow of the patient has entered a deteriorating state. From time t5 to time t7, the first difference continuously shows a gradually increasing situation. Therefore, it can be judged that the microcirculation blood flow of the patient is in a continuously deteriorating state. When it is monitored that the first difference gradually decreases during the third preset time period between time t8 and time t7, it can be judged at this time that the microcirculation blood flow of the patient has entered a recovery state starting from time t7.

[0077] In one embodiment, after determining that the microcirculation blood flow at a specific limb of the patient has entered a recovery state, a prompt message for microcirculation recovery can also be generated to estimate the feasibility of the patient's shock resuscitation. After determining that the microcirculation blood flow at a specific limb of the patient has entered a deteriorating state, a warning message for microcirculation deterioration can also be generated. The warning message is used to warn of the deterioration of the patient's shock condition, warning that the patient may have thrombosis or other adverse symptoms, so that medical staff can intervene early in the deterioration of the patient's shock condition and take preventive measures in time before the patient's condition becomes more serious.

[0078] Figure 5 This is a schematic flowchart of the method for determining the microcirculation state of a patient in the second judgment mode in one embodiment of this application. In one embodiment, in the second judgment mode, determining the microcirculation state of the patient according to the ideal body surface skin temperature corresponding to the body surface skin temperature and the environmental temperature may include the following steps S410 to step S420.

[0079] Step S410: Determine the ideal body surface skin temperature corresponding to the current environmental temperature according to the corresponding relationship between the environmental temperature and the ideal body surface skin temperature at a specific limb.

[0080] The ideal body surface skin temperature can refer to the average limb skin temperature of healthy individuals under similar environmental conditions, and the ideal body surface skin temperature can be determined in advance through literature research or measured on healthy people in a specific environment. By pre-determining the ideal body surface skin temperature of the body surface skin temperature at specific limb positions of the human body under different temperature environments, a comparison table of environmental temperature - ideal body surface skin temperature can also be established.

[0081] Figure 6 This is a schematic diagram of the comparison table of environmental temperature - ideal body surface skin temperature in one embodiment of the present application, showing the ideal skin temperature of different parts of the human body at different environmental temperatures. According to Figure 6 it can be seen that different parts of the human body are affected by the environment to different degrees. Among them, the rectum is the least affected by the environmental temperature, and the feet are the most affected by the environmental temperature. Using the comparison table of environmental temperature - ideal body surface skin temperature, it is possible to more conveniently and quickly determine the ideal body surface skin temperature at a specific limb position of the patient under the current environmental temperature.

[0082] Considering that in the actual monitoring of patients, there may be situations where the patient is transferred, or the temperature of the environment where the patient is located changes significantly. Usually, the limb temperature of the human body is more affected by environmental changes, while the intracavitary temperature of the human body changes less with the environment. Therefore, when the environmental temperature changes greatly, if the change trend of the difference between the body surface skin temperature at a specific limb position (such as toes) of the patient and the intracavitary temperature of the patient is still compared, it may lead to inaccurate judgment of the microcirculation change situation of the patient and incorrect conclusions. Therefore, when the environmental temperature changes greatly, the second judgment mode is used to determine the microcirculation state of the patient, that is, the current microcirculation state of the patient is judged according to the body surface skin temperature at a specific limb position of the patient and the ideal body surface skin temperature of the human body under the current environmental temperature.

[0083] Step S420: When the body surface skin temperature is less than the ideal body surface skin temperature, and the second difference between the ideal body surface skin temperature and the body surface skin temperature is greater than the fourth threshold, it is determined that the patient has insufficient microcirculation.

[0084] Continuously monitor the skin surface temperature at a specific limb of the patient and determine the ideal skin surface temperature at the specific limb of the patient under the current ambient temperature, and compare the actual skin surface temperature with the ideal skin surface temperature. When the actual skin surface temperature at the specific limb position (such as the toe) of the patient is less than the ideal skin surface temperature, and the second difference between the ideal skin surface temperature and the skin surface temperature is greater than the fourth threshold, it can be determined that microcirculation insufficiency has occurred at the specific limb position of the patient. It should be noted that in this application, the second difference refers to the difference between the ideal skin surface temperature minus the skin surface temperature. Since the skin surface temperature is less than the ideal skin surface temperature at this time, the second difference is also a positive number. The fourth threshold can also be reasonably set according to actual application requirements. Preferably, the fourth threshold can be a value greater than zero.

[0085] In the monitoring method for human microcirculation changes provided in this application, in the second judgment mode, according to the relationship between the skin surface temperature at the specific limb position of the patient and the ideal skin surface temperature corresponding to the ambient temperature, it is determined whether the patient has microcirculation insufficiency. Similarly, after it is determined that microcirculation insufficiency has occurred at the specific limb of the patient, a warning message for microcirculation insufficiency can also be generated, and the warning message is used to warn of the deterioration of the patient's shock condition.

[0086] In one embodiment, please refer to Figure 5 , after it is determined that the patient has microcirculation insufficiency, the method may include the following steps S430 to step S450.

[0087] Step S430: Monitor the change of the second difference within the fourth preset time period.

[0088] In the case where it is determined that the patient has microcirculation insufficiency, it is also possible to analyze whether the patient's microcirculation is in a recovery state or a deteriorating state based on the changes in the skin surface temperature at the specific limb position of the patient and the ideal skin surface temperature corresponding to the current ambient temperature, and then the feasibility of the patient's shock resuscitation can be estimated based on the changes in the patient's microcirculation.

[0089] Step S440: When the second difference gradually decreases within the fourth preset time period, it is determined that the patient's microcirculation blood flow enters the recovery state.

[0090] Step S450: When the second difference gradually increases within the fourth preset time period, it is determined that the patient's microcirculation blood flow enters the deteriorating state.

[0091] Continuing the trend of change of the second difference between the ideal body surface skin temperature corresponding to the current ambient temperature and the actual body surface skin temperature at a specific limb of the patient, a continuous trend change curve of the second difference can also be generated according to the change of the second difference. Based on the continuous trend change curve of the second difference, the change of the second difference can be intuitively understood. When the second difference shows a gradually decreasing trend within the fourth preset time period, it indicates that the microcirculation blood flow at the specific limb of the patient enters a recovery state. When the second difference shows a gradually increasing trend within the fourth preset time period, it indicates that the microcirculation blood flow at the specific limb of the patient enters a deteriorating state. Similarly, after determining that the microcirculation blood flow at the specific limb of the patient enters a recovery state or a deteriorating state, corresponding prompt information is generated to facilitate medical staff to timely understand the patient's condition.

[0092] Figure 7 is a schematic diagram of the continuous trend change curve of the intracavity temperature and the toe temperature in one embodiment of the present application. In this embodiment, taking Figure 7 the change of the intracavity temperature and the toe temperature shown as an example to illustrate the determination of the microcirculation state at a specific limb of the patient in the present application using the second judgment mode. The description is relatively specific and detailed, but it should not be construed as a limitation on the scope of the invention patent.

[0093] When determining the microcirculation state of the patient using the second judgment mode, at time t9, the toe temperature of the patient is lower than the ideal toe temperature, and the second difference between the ideal toe temperature and the toe temperature is greater than the fourth threshold. Therefore, it can be judged that the patient has microcirculation insufficiency at the toe at time t9. When it is judged that the patient has microcirculation insufficiency, the change of the second difference between the ideal toe temperature and the toe temperature is continuously monitored. When it is monitored that the second difference gradually increases during the fourth preset time period between time t9 and time t10, it can be judged at this time that the microcirculation blood flow of the patient enters a deteriorating state. From time t9 to time t11, the second difference continues to gradually increase. Therefore, it can be judged that the microcirculation blood flow of the patient is in a continuous deteriorating state. When it is monitored that the second difference gradually decreases during the fourth preset time period between time t11 and time t12, it can be judged at this time that the microcirculation blood flow of the patient enters a recovery state starting from time t11.

[0094] It should be understood that although the steps in the flowchart of the accompanying drawings of the specification are shown in sequence according to the indication of the arrows, these steps are not necessarily executed in the sequence indicated by the arrows. Unless there is a clear description in this article, there is no strict sequence limit for the execution of these steps, and these steps can be executed in other sequences. Moreover, at least a part of the steps in the flowchart of the accompanying drawings of the specification may include multiple steps or multiple stages. These steps or stages are not necessarily executed at the same time, but can be executed at different times. The execution sequence of these steps or stages is not necessarily sequential, but can be executed alternately or in turn with at least a part of other steps or steps or stages in other steps.

[0095] Based on the description of the embodiments of the method for monitoring human microcirculation changes above, the present application also provides a device for monitoring human microcirculation changes. The device may include a system (including a distributed system), software (application), module, component, server, client, etc. that uses the method described in the embodiments of this specification and combines the necessary implementation hardware. Based on the same inventive concept, the devices in one or more embodiments provided by the embodiments of the present application are as described in the following embodiments. Since the implementation solutions for the device to solve problems are similar to the method, the implementation of the specific device in the embodiments of this specification can refer to the implementation of the foregoing method, and the repeated parts will not be described again. As used hereinafter, the term "unit" or "module" may be a combination of software and / or hardware that can achieve a predetermined function. Although the devices described in the following embodiments are preferably implemented in software, implementation in hardware, or a combination of software and hardware is also possible and contemplated.

[0096] The present application also provides a device for monitoring human microcirculation changes. Figure 8 FIG. is a schematic structural diagram of the device for monitoring human microcirculation changes in one embodiment of the present application. In one embodiment, the device for monitoring human microcirculation changes may include a body surface temperature monitoring module 100, a cavity temperature monitoring module 200, an environmental temperature monitoring module 300, and a control module 400.

[0097] The body surface temperature monitoring module 100 can be used to monitor the skin temperature of the body surface at a specific limb of the patient. In some feasible embodiments, the body surface temperature monitoring module 100 may include, but is not limited to, a surface temperature sensor or an infrared thermometer. The skin temperature of the extremities (such as fingers and toes) can be quickly obtained by using the surface temperature sensor or the infrared thermometer. Preferably, the body surface temperature monitoring module 100 is mainly used to measure the skin temperature at the toe position of the patient.

[0098] The intracavitary temperature monitoring module 200 can be used to monitor the intracavitary temperature of a patient. In practical applications, appropriate intracavitary temperature monitoring points can be selected according to specific application scenarios, such as the rectum, esophagus, or bladder. The intracavitary temperature monitoring module 200 can include corresponding temperature probes, and the corresponding temperature probes are used to measure the intracavitary temperature. Preferably, the intracavitary temperature monitoring module 200 is mainly used to measure the intracavitary temperature at the rectum of the patient.

[0099] The ambient temperature monitoring module 300 can be used to monitor the ambient temperature. In some feasible embodiments, the body surface temperature monitoring module 100 can include, but is not limited to, a dry bulb thermometer, a natural wet bulb thermometer, and a globe thermometer. The ambient temperature measurement instruments such as the dry bulb thermometer, the natural wet bulb thermometer, and the globe thermometer are used to measure the ambient temperature.

[0100] The control module 400 can be respectively connected to the body surface temperature monitoring module 100, the intracavitary temperature monitoring module 200, and the ambient temperature monitoring module 300. When the control module 400 receives a start instruction from the user, the control module 400 can automatically select the first judgment mode as the microcirculation judgment mode. Under normal circumstances, the ambient temperature where the patient is located is stable (for example, in-hospital monitoring or emergency site monitoring). Therefore, in this embodiment, the first judgment mode can be used as the default mode. After the microcirculation monitoring device for the human body receives the start instruction and starts the microcirculation monitoring for the patient, the control module 400 defaults to select the first judgment mode to judge the microcirculation state of the patient.

[0101] The control module 400 can be used to receive and continuously monitor the specific data and changes of information such as the ambient temperature, the body surface skin temperature at a specific limb of the patient, and the intracavitary temperature of the patient. In the first judgment mode, the control module 400 can determine the microcirculation state of the patient according to the body surface skin temperature and the intracavitary temperature. When operating in the first judgment mode, and when the control module 400 determines that the first switching condition is met according to the ambient temperature, the microcirculation judgment mode is switched from the first judgment mode to the second judgment mode.

[0102] In the second judgment mode, the control module 400 can determine the microcirculation state of the patient according to the body surface skin temperature and the ideal body surface skin temperature corresponding to the ambient temperature. When operating in the second judgment mode, and when the control module 400 determines that the second switching condition is met according to the ambient temperature, the microcirculation judgment mode is switched from the second judgment mode to the first judgment mode.

[0103] When the body surface temperature monitoring module 100 monitors the body surface skin temperature at a specific limb of a patient in real time, it can also synchronously generate a continuous change curve of the body surface skin temperature at the specific limb of the patient. The intracavity temperature monitoring module 200 can also generate a continuous change curve of the intracavity temperature of the patient, and the ambient temperature monitoring module 300 can also generate a continuous change curve of the ambient temperature. Further, the control module 400 can determine the change trend of the above temperature information based on the continuous change curves of the body surface skin temperature, the intracavity temperature, and the ambient temperature, and select a suitable microcirculation judgment mode according to the body surface skin temperature at the test position of the specific limb position of the patient, the temperature differences between the intracavity temperature, the ambient temperature, the ideal body surface skin temperature, etc., and the change of the temperature difference, and determine the microcirculation blood flow change conditions at different positions of the limb based on the suitable microcirculation judgment mode.

[0104] For the monitoring device for human microcirculation change provided by the present application, the body surface temperature monitoring module 100, the intracavity temperature monitoring module 200, and the ambient temperature monitoring module 300 respectively monitor the body surface skin temperature at a specific limb of the patient, the intracavity temperature of the patient, and the ambient temperature where the patient is located in real time. The control module 400 can determine to use the first judgment mode or the second judgment mode to judge the microcirculation state of the patient according to the ambient temperature where the patient is located. In the first judgment mode, the control module 400 determines the microcirculation state of the patient according to the body surface skin temperature and the intracavity temperature; in the second judgment mode, the control module 400 determines the microcirculation state of the patient according to the ideal body surface skin temperature corresponding to the body surface skin temperature and the ambient temperature. By evaluating the microcirculation change of the patient based on the ambient temperature, the body surface skin temperature at a specific limb of the patient, and the intracavity temperature of the patient, the above device can realize non-invasive monitoring of the microcirculation change of the patient, help to identify the microcirculation abnormality of the patient earlier, and realize the early warning analysis of the patient's condition. Selecting the first judgment mode or the second judgment mode as the microcirculation judgment mode based on the ambient temperature can reduce the influence of the ambient temperature on the evaluation result of the patient's microcirculation state and improve the accuracy of the evaluation result of the patient's microcirculation state.

[0105] In one embodiment, the body surface temperature monitoring module 100 may include one or more skin temperature sensors. The skin temperature sensors can be fixed at a specific limb of the patient through heat insulation protection materials. When the skin temperature sensors are wrapped or adhered to the skin at the specific limb position of the patient by using the heat insulation protection materials, it can ensure that the temperature inside the heat insulation protection materials is not affected by the outer ambient temperature. That is, when monitoring the body surface skin temperature of the patient, using the skin temperature sensors with heat insulation protection layer materials can effectively improve the measurement accuracy and reliability, reduce the influence of the external ambient temperature on the sensor reading, ensure that the measured is the true skin surface temperature rather than the surrounding environment temperature, and obtain reliable body surface skin temperature data in different environments.

[0106] In some feasible embodiments, the selected thermal insulation protection material can be made into a thin sheet or film form and then fixed to the sensor device by means such as adhesives, stitching, or molding. For adhesive sensors, the thermal insulation material can also be integrated into the design of medical tapes or patches; for wearable devices, it can be directly embedded into fabrics or plastic casings.

[0107] In one of the embodiments, when the specific limb of the patient is the toes of the patient's feet, the body surface temperature monitoring module determines the highest value of the toe temperature collected as the body surface skin temperature. Considering that the toes are part of the distal limbs and are more susceptible to changes in vascular microcirculation. In the case of a patient with microcirculation disorders or shock, the blood perfusion of the feet is usually the first to be affected.

[0108] However, even on the same foot of the same patient, there may be differences in temperature between different toes. Determining the highest value of the toe temperature collected as the body surface skin temperature can better reflect the patient's microcirculation blood perfusion situation. By selecting the highest toe temperature as the body surface skin temperature, a more conservative estimate is provided, which helps to prevent underestimating the patient's body temperature condition and can more accurately capture the true trend of the patient's body surface temperature change. Especially when evaluating the patient's microcirculation status, this helps to detect potential problems earlier and take appropriate intervention measures. At the same time, by selecting the highest toe temperature as the body surface skin temperature, it is also possible to avoid the influence of low-temperature readings caused by poor contact of individual sensors or other accidental factors on the overall judgment, making real-time monitoring more efficient and feasible.

[0109] In one embodiment, the monitoring device for human microcirculation changes may further include a display module. The display module may be connected to the control module 400 and is used to display real-time monitoring data such as the ambient temperature, the skin surface temperature at a specific limb of the patient, and the patient's intracavitary temperature. When the body surface temperature monitoring module 100 generates a continuous change curve of the skin surface temperature at a specific limb of the patient, the intracavitary temperature monitoring module 200 generates a continuous change curve of the patient's intracavitary temperature, and the ambient temperature monitoring module 300 generates a continuous change curve of the ambient temperature, the display module can also synchronously display the continuous change curves of the skin surface temperature, the intracavitary temperature, and the ambient temperature, so as to facilitate the user to more intuitively understand the temperature change of the patient. After the control module 400 determines the microcirculation change of the patient according to the above-mentioned monitoring method for human microcirculation changes, the control module 400 can also output different control signals according to different microcirculation states of the patient, so that the display module can display corresponding warning information according to the control signals. For example, when the control module 400 determines that there is microcirculation insufficiency at a specific limb of the patient, the control module 400 can output a control signal to the display module to control the display module to display a warning message of microcirculation insufficiency.

[0110] After the control module 400 determines that the microcirculation blood flow at a specific limb of the patient enters the recovery state, it can also control the display module to display a prompt message of microcirculation recovery to estimate the feasibility of the patient's shock resuscitation. After the control module 400 determines that the microcirculation blood flow at a specific limb of the patient enters the deteriorating state, it can also control the display module to display a warning message of microcirculation deterioration. The warning information is used to warn of the deterioration of the patient's shock condition, indicating that there may be thrombosis or other adverse symptoms in the patient, so that medical staff can intervene early in the deterioration of the patient's shock condition and take preventive measures in time before the patient's condition becomes more serious.

[0111] It can be understood that the various embodiments of the above methods in this specification are all described in a progressive manner. The same / similar parts between the various embodiments can be referred to each other, and the key points of each embodiment are the differences from other embodiments. For the relevant parts, refer to the descriptions of other method embodiments.

[0112] Those of ordinary skill in the art can understand that all or part of the processes in the methods of the above embodiments can be completed by instructing relevant hardware through a computer program. The computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above methods. Among them, any reference to a memory, database, or other medium used in the embodiments provided by the present disclosure can include at least one of non-volatile and volatile memories. Non-volatile memories can include read-only memory (ROM), magnetic tapes, floppy disks, flash memories, optical memories, high-density embedded non-volatile memories, resistive random access memories (ReRAM), magnetoresistive random access memories (MRAM), ferroelectric random access memories (FRAM), phase change memories (PCM), graphene memories, etc. Volatile memories can include random access memory (RAM) or external cache memories, etc. By way of illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM), etc. The databases involved in the embodiments provided by the present disclosure can include at least one of relational databases and non-relational databases. Non-relational databases can include distributed databases based on blockchain, etc., without limitation. The processors involved in the embodiments provided by the present disclosure can be general-purpose processors, central processing units, graphics processing units, digital signal processors, programmable logics, data processing logics based on quantum computing, etc., without limitation. Each embodiment in this specification is described in a progressive manner. The same or similar parts among the embodiments can be referred to each other. Each embodiment focuses on the differences from other embodiments. In particular, for the hardware + program type embodiments, since they are basically similar to the method embodiments, they are described relatively simply. The relevant parts can be referred to the description of the method embodiments.

[0113] It should be noted that the above-mentioned devices, electronic devices, servers, etc. may also include other implementation manners according to the description of the method embodiments. The specific implementation manners can be referred to the description of the relevant method embodiments. At the same time, new embodiments formed by the mutual combination of the features among the various methods and the embodiments of the devices, equipment, and servers still fall within the scope covered by the present disclosure, and will not be elaborated one by one here.

[0114] In the description of this specification, the descriptions referring to terms such as "some embodiments", "other embodiments", "ideal embodiments", etc. mean that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic descriptions of the above terms do not necessarily refer to the same embodiment or example.

[0115] The technical features of the above-described embodiments can be combined arbitrarily. For the sake of brevity of description, not all possible combinations of the various technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as within the scope described in this specification.

[0116] The above-described embodiments merely represent several implementation manners of the present invention. The descriptions thereof are relatively specific and detailed, but should not be construed as a limitation on the scope of the invention patent. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present invention, several modifications and improvements can still be made, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the invention patent should be subject to the appended claims.

Claims

1. A method for monitoring changes in human microcirculation, characterized in that: include: monitoring the skin temperature of a patient at a specific extremity and the intracavitary temperature of said patient; Determining the microcirculation state of the patient according to the skin temperature and the intracavitary temperature; When the skin temperature is lower than the cavity temperature, and a first difference between the cavity temperature and the skin temperature is greater than a third threshold, it is determined that insufficient microcirculation occurs in the specific limb of the patient; After determining that the patient has insufficient microcirculation, the method further includes: Monitoring the change of the first difference within a third preset time period; When the first difference gradually decreases within the third preset time period, it is determined that the microcirculation blood flow of the patient enters a recovery state; When the first difference gradually increases within the third preset time period, it is determined that the microcirculation blood flow of the patient has entered a deteriorated state.

2. A method for monitoring changes in human microcirculation, characterized in that: include: Monitor ambient temperature and the patient's skin temperature at specific extremities; monitoring the ambient temperature and the skin temperature of a specific limb of the patient; determining the microcirculation state of the patient according to the body surface skin temperature and the ideal body surface skin temperature corresponding to the ambient temperature; Determining the ideal skin temperature corresponding to the current ambient temperature according to the corresponding relationship between the ambient temperature and the ideal skin temperature at a specific limb; When the body surface skin temperature is lower than the ideal body surface skin temperature, and a second difference between the ideal body surface skin temperature and the body surface skin temperature is greater than a fourth threshold, it is determined that the patient has insufficient microcirculation; After determining that the patient has insufficient microcirculation, the method further includes: Monitoring the change of the second difference within a fourth preset time period; When the second difference gradually decreases within the fourth preset time period, it is determined that the microcirculation blood flow of the patient enters a recovery state; When the second difference gradually increases within the fourth preset time period, it is determined that the microcirculation blood flow of the patient has entered a deteriorated state.

3. A monitoring device for human microcirculation changes, characterized in that: include: A body surface temperature monitoring module, used to monitor the body surface skin temperature of a patient's specific limbs; An intracavitary temperature monitoring module, used for monitoring the intracavitary temperature of the patient; Ambient temperature monitoring module, used to monitor ambient temperature; A control module, connected to the body surface temperature monitoring module, the intracavity temperature monitoring module and the ambient temperature monitoring module, respectively, for monitoring the body surface skin temperature of a specific limb of a patient and the intracavity temperature of the patient; Determining the microcirculation state of the patient according to the skin temperature and the intracavitary temperature; When the skin temperature is lower than the cavity temperature, and a first difference between the cavity temperature and the skin temperature is greater than a third threshold, it is determined that insufficient microcirculation occurs in the specific limb of the patient; After determining that the patient has microcirculation deficiency, the method further includes monitoring the change of the first difference within a third preset time period; when the first difference gradually decreases within the third preset time period, determining that the microcirculation blood flow of the patient has entered a recovery state; when the first difference gradually increases within the third preset time period, determining that the microcirculation blood flow of the patient has entered a deterioration state; Or, used to monitor the ambient temperature and the skin temperature of a patient's specific limb; monitor the ambient temperature and the skin temperature of a patient's specific limb; determine the patient's microcirculation state according to the skin temperature and the ideal skin temperature corresponding to the ambient temperature; According to the correspondence between the ambient temperature and the ideal body surface skin temperature of a specific limb, the ideal body surface skin temperature corresponding to the current ambient temperature is determined; when the body surface skin temperature is lower than the ideal body surface skin temperature, and a second difference between the ideal body surface skin temperature and the body surface skin temperature is greater than a fourth threshold, it is judged that the patient has microcirculation insufficiency, and after judging that the patient has microcirculation insufficiency, the change of the second difference within a fourth preset time period is monitored; when the second difference gradually decreases within the fourth preset time period, it is judged that the microcirculation blood flow of the patient has entered a recovery state; when the second difference gradually increases within the fourth preset time period, it is judged that the microcirculation blood flow of the patient has entered a deterioration state.

4. The device for monitoring changes in human microcirculation according to claim 3, characterized in that: The body surface temperature monitoring module includes one or more skin temperature sensors, and the skin temperature sensors are fixed to the specific limbs of the patient through thermal insulation protection materials.

5. The device for monitoring changes in human microcirculation according to claim 3, characterized in that: When the patient's specific limbs are the toes of both feet of the patient, the body surface temperature monitoring module determines the maximum value of the collected toe temperature as the body surface skin temperature.

6. The device for monitoring changes in human microcirculation according to claim 3, characterized in that: The monitoring device for human microcirculation changes also includes: A display module, connected to the control module, for displaying the ambient temperature, the skin temperature of a specific limb of the patient, and the intracavitary temperature of the patient; The control module is further used to output different control signals according to different microcirculation states of the patient, and the display module is further used to display early warning information according to the control signal.

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