Traditional Chinese medicine prescription for treating stomach fire flourishing erosive gastritis

Abstract

The invention relates to a traditional Chinese medicine prescription for treating stomach fire flourishing erosive gastritis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicines in parts by weight: angelica sinensis, radix rehmanniae recen, moutan bark, rhizoma cimicifugae, coptis chinensis, fructus evodiae, trogopterus dung and pollen typhae. The curative effect of the traditional Chinese medicine prescription is verified through scientific formulation of classic prescriptions, experimental research and years of clinical use. The traditional Chinese medicine composition has a good curative effect on stomach fire exuberance erosive gastritis, and can significantly relieve stomachache, sour regurgitation, heartburn and other symptoms.

Description

Technical Field

[0001] The present invention relates to the field of traditional Chinese medicine, and particularly to a traditional Chinese medicine prescription for treating erosive gastritis with excessive stomach fire syndrome. Background Art

[0002] Erosive gastritis (EG) is a common digestive system disease, mainly a chronic inflammatory lesion of the gastric mucosa caused by various factors. Endoscopically, the gastric mucosa shows flat or elevated erosions, with mucosal congestion, exudation, and edema. Clinically, it mainly presents as non-specific dyspepsia, such as fullness or pain in the upper abdomen after eating, noisy acid reflux, belching and other discomforts. Traditional Chinese medicine classifies erosive gastritis into the categories of "epigastric pain" and "stagnation and fullness". A large-scale, multi-center study in China in 2014, "Chronic gastritis in China: a national multi-center survey", included 8,892 patients with chronic gastritis. The results showed that patients with erosive gastritis accounted for 42.3%. Erosive gastritis is characterized by a high incidence, a long course, and repeated attacks. Modern medical research shows that persistent gastric mucosal inflammatory reactions can lead to irreversible tissue damage and there is a risk of transformation into atrophic gastritis or even gastric cancer. Therefore, early intervention and effective treatment are particularly important.

[0003] Currently, the western medicine treatment of erosive gastritis mainly adopts symptomatic treatment and etiological treatment. For patients with Helicobacter pylori (HP) infection, HP eradication treatment is usually given first, and drugs such as proton pump inhibitors (PPIs), H2 receptor antagonists, and gastric mucosal protectants are given for symptoms such as stomach pain, bloating, acid reflux and heartburn. However, the western medicine treatment still has certain limitations. For example, the symptom relief effect of some patients is not good, and it is easy to relapse after stopping the drug. In addition, patients receiving triple or quadruple therapy for HP eradication may have a poor response to the drugs and are accompanied by adverse reactions such as dry mouth, bitter taste in the mouth, and hiccups, affecting the compliance of the patients. In contrast, the traditional Chinese medicine treatment of erosive gastritis follows the principle of "treating the disease by seeking the root cause and syndrome differentiation and treatment". Through the comprehensive diagnosis of the four diagnostic methods, individualized treatment is carried out according to the different pathogenesis characteristics of the patients. The inventor extended the traditional Chinese medicine inspection by observation to under the gastroscope and believes that the pathogenesis of gastric mucosal erosion, redness and congestion is due to excessive stomach fire forcing blood to flow erratically. Therefore, in the treatment, methods of clearing heat and cooling blood, promoting blood circulation to remove stasis, regulating qi and harmonizing the stomach should be adopted to quickly relieve clinical symptoms, promote the repair of the gastric mucosa, and effectively reduce the recurrence rate. In clinical practice, this treatment method has shown good curative effect and feasibility.

[0004] The present invention provides a traditional Chinese medicine formula for erosive gastritis with excessive stomach fire syndrome. The prescription is derived from the inventor's clinical practice experience of more than 30 years and long-term gastroscope observation summary, and through addition, subtraction and compatibility, it is applicable to patients with erosive gastritis of different syndromes. The content range of the medicinal materials covered by the claims of the present invention is specifically designed for the research and development of traditional Chinese medicine finished products. Its formula and dosage have been refined and optimized and have not been publicly disclosed before. The formula of the present invention is not only applicable to patients with erosive gastritis of excessive stomach fire syndrome, but also has high safety and definite curative effect. It is particularly suitable for developing into a traditional Chinese medicine preparation for treating erosive gastritis, and has broad clinical application prospects and industrialization value. Summary of the Invention

[0005] The present invention provides a traditional Chinese medicine formula specifically for treating erosive gastritis with excessive stomach fire syndrome, which is suitable for developing into various main traditional Chinese medicine preparations, filling the blank of domestic traditional Chinese medicine preparations dedicated to treating erosive gastritis with excessive stomach fire syndrome. The traditional Chinese medicine formula provided by the present invention for treating erosive gastritis with excessive stomach fire syndrome has definite curative effect, refined and safe formula, and is suitable for the development of new traditional Chinese medicines.

[0006] The technical solution adopted by the present invention is: a traditional Chinese medicine composition for treating erosive gastritis with excessive stomach fire syndrome, which is characterized by being made of the following traditional Chinese medicines in parts by weight. The "parts" in the present invention refer to the parts by weight of dry traditional Chinese medicinal materials, and each part corresponds to 1 gram: 10-30 parts of Angelica sinensis, 10-30 parts of Rehmannia glutinosa, 5-15 parts of Cortex Moutan, 5-15 parts of Rhizoma Cimicifugae, 5-20 parts of Coptis chinensis, 1-10 parts of Evodia rutaecarpa, 5-20 parts of Faeces Trogopterori, 10-30 parts of Pollen Typhae. The ratio of each medicinal material in the composition needs to meet: the weight ratio of Coptis chinensis to Evodia rutaecarpa is 10:3.

[0007] As an optimal option: the composition of the traditional Chinese medicine raw materials in parts by weight is as follows: 12-20 parts of Angelica sinensis, 12-20 parts of Rehmannia glutinosa, 8-12 parts of Cortex Moutan, 5-10 parts of Rhizoma Cimicifugae, 5-15 parts of Coptis chinensis, 2-5 parts of Evodia rutaecarpa, 8-12 parts of Faeces Trogopterori, 12-18 parts of Pollen Typhae. The ratio of each medicinal material in the composition needs to meet: the weight ratio of Coptis chinensis to Evodia rutaecarpa is 10:3.

[0008] More preferably, the composition of the traditional Chinese medicine raw materials in parts by weight is: 15 parts of Angelica sinensis, 15 parts of Rehmannia glutinosa, 10 parts of Cortex Moutan, 10 parts of Rhizoma Cimicifugae, 10 parts of Coptis chinensis, 3 parts of Evodia rutaecarpa, 10 parts of Faeces Trogopterori, 15 parts of Pollen Typhae. The ratio of each medicinal material in the composition needs to meet: the weight ratio of Coptis chinensis to Evodia rutaecarpa is 10:3.

[0009] The functions and indications of the traditional Chinese medicine prescription of the present invention are as follows: clearing heat and cooling blood, promoting blood circulation to remove blood stasis, regulating qi and harmonizing the stomach. It is applicable to erosive gastritis with excessive stomach fire syndrome caused by improper diet, excessive consumption of spicy food or emotional disorders, etc., resulting in the failure of the spleen and stomach to transport and transform, and the endogenous generation of stomach fire. The symptoms include fullness and discomfort or pain in the epigastric region, voracious appetite, thirst, or bad breath, acid reflux and heartburn, belching, dry stools, reduced frequency of defecation, red tongue, yellow coating, and rapid pulse.

[0010] The formula analysis, that is, the mechanism of action, is as follows:

[0011] The core etiological mechanism of erosive gastritis with excessive stomach fire syndrome is improper diet, excessive consumption of spicy food or emotional disorders, etc., resulting in the failure of the spleen and stomach to transport and transform, excessive stomach fire, and forced blood to flow erratically. In view of the pathogenesis characteristics of erosive gastritis with excessive stomach fire syndrome, this prescription is created by the principles of clearing heat and cooling blood, promoting blood circulation to remove blood stasis, and regulating qi and harmonizing the stomach. This prescription is composed of classic prescriptions such as Qingwei Powder, Zuojin Pills, and Shixiao Powder. The main prescription is based on Qingwei Powder (Coptis chinensis, Cimicifuga foetida, Rehmannia glutinosa, Angelica sinensis, Paeonia suffruticosa). Coptis chinensis is bitter and cold in nature and purges fire. Firstly, it purges liver fire, so that the liver fire can be cleared and will not horizontally invade the stomach; secondly, it clears and purges stomach heat, and when the stomach fire subsides, its qi will naturally harmonize; thirdly, it clears and purges heart fire, with the meaning of "purging the son when the mother is excessive". One medicine purges the fire of the liver, stomach, and heart, taking both the root and the branch into consideration. Combined with Evodia rutaecarpa, it forms Zuojin Pills. A small amount of pungent and hot Evodia rutaecarpa is used to disperse liver qi stagnation, lower stomach qi rebellion, and counteract the bitter cold of Coptis chinensis. Modern pharmacological research has found that Zuojin Pills have effects such as anti-ulcer, inhibiting gastric acid secretion, antibacterial, and analgesic and anti-inflammatory effects. Rehmannia glutinosa is sweet, cold, and nourishes blood and yin, repairing the burned stomach collaterals. Paeonia suffruticosa clears heat and cools blood, disperses stasis and relieves pain, specifically targeting the stasis heat caused by stomach fire burning the collaterals. Angelica sinensis is sweet, pungent, and warm, nourishing and harmonizing blood. Cimicifuga foetida disperses fire toxin, guides all the medicines to the Yangming meridian, and helps Coptis chinensis to disperse the stagnant fire in the stomach. Shixiao Powder (Trogopterus dung, Pollen Typhae) is used as an adjunct to promote blood circulation and remove blood stasis. Trogopterus dung is bitter, salty, sweet, and warm, entering the blood meridian of the liver, and is good at promoting blood circulation and removing blood stasis, dispersing stasis and relieving pain; Pollen Typhae is sweet and flat, promoting blood circulation and stopping bleeding. The two medicines are used together synergistically to promote blood circulation to remove blood stasis and dissipate stasis and relieve pain. Modern pharmacological research has found that Shixiao Powder has effects such as dilating blood vessels, reducing vascular resistance, increasing blood flow, and promoting blood coagulation. All the medicines are used together to achieve the effects of clearing heat and cooling blood, and promoting blood circulation to remove blood stasis.

[0012] The pharmacological effects of each compatible traditional Chinese medicine in the prescription are described as follows:

[0013] Angelica sinensis: The dried root of Angelica sinensis, a plant of the Umbelliferae family. It is warm in nature, sweet and pungent in taste. It belongs to the liver, heart, and spleen meridians. Its functions are to enrich blood and promote blood circulation, regulate menstruation and relieve pain, moisten the intestines and relieve constipation. It is used for sallow complexion due to blood deficiency, dizziness and palpitations, irregular menstruation, amenorrhea and dysmenorrhea, deficiency-cold abdominal pain, rheumatic arthralgia, traumatic injury, carbuncle and ulcer, and intestinal dryness and constipation. The main components in modern research include phthalides and their dimers, ferulic acid, polysaccharides, flavonoids, amino acids, trace elements, etc. It has effects such as repairing hematopoietic function, regulating angiogenesis, inhibiting cardiomyocyte hypertrophy, anti-arrhythmia, anti-platelet aggregation, promoting nerve regeneration, promoting immunity, anti-tumor, anti-radiation, anti-inflammatory and analgesic, antioxidant, and anti-aging effects.

[0014] Rehmannia Root: The dried tuberous root of Rehmannia glutinosa Libosch. (Family Scrophulariaceae). Cold in nature, sweet in taste. It acts on the heart, liver and kidney meridians. Its functions are to clear heat and cool blood, and nourish yin and promote the production of body fluid. It is used for heat invading nutrient-blood, epidemic toxin causing maculae, hematemesis and epistaxis, consumption of yin due to febrile disease, crimson tongue with vexing thirst, constipation due to fluid impairment, yin deficiency fever, steaming bone fever, internal heat thirst. Modern research shows that its main components include iridoids, ionones, phenyl ethanol glycosides, triterpenoids, flavonoids, saccharides, lignans, phenolic acids, amino acids, volatile oils and inorganic elements, etc. It has the effects of hemostasis, treating cardiovascular diseases, improving cognitive and memory defects, enhancing immunity, regulating blood sugar and lipids, anti-aging, anti-tumor, bacteriostasis, anti-gastric ulcer and protecting gastric mucosa, etc.

[0015] Moutan Bark: The dried root bark of Paeonia suffruticosa Andr. (Family Ranunculaceae). Slightly cold in nature, bitter and pungent in taste. It acts on the heart, liver and kidney meridians. Its functions are to clear heat and cool blood, and promote blood circulation to remove blood stasis. It is used for heat invading nutrient-blood, epidemic toxin causing maculae, hematemesis and epistaxis, feverish sensation at night with early morning relief, bone steaming without sweating, amenorrhea and dysmenorrhea, traumatic injury, carbuncles and sores. Modern research shows that its main components include phenols and glycosides, monoterpenes and their glycosides, triterpenoids, sterols, organic acids, flavonoids, coumarins, polysaccharides and volatile oils, etc. Among them, paeonol, paeoniflorin, gallic acid, oxypaeoniflorin, catechin, moutan glycoside C, benzoyl oxypaeoniflorin, etc. are its main active components. It has the effects of bacteriostasis and anti-inflammation, anti-tumor, anti-arrhythmia, hypoglycemic, activating the body's immune system and protecting the cardiovascular system, etc.

[0016] Black Cohosh Rhizome: The dried rhizome of Cimicifuga heracleifolia Kom., Cimicifuga dahurica (Turcz.) Wormsk. or Cimicifuga foetida L. (Family Ranunculaceae). Slightly cold in nature, pungent and slightly sweet in taste. It acts on the lung, spleen, stomach and large intestine meridians. It is used to induce sweating and promote eruption, clear heat and detoxify, and lift yang qi. It is used for headache due to wind-heat, toothache, aphtha, sore throat, measles not out, yang toxin causing maculae, rectal prolapse, uterine prolapse. Modern research shows that its main components include triterpenoids and their glycosides, phenolic acids, chromones, lignans, indolones, alkaloids, amides, sterols, sugars and volatile oils, etc. Its active components mainly come from cycloartenane-type tetracyclic triterpenoid compounds and phenolic acid compounds. It has the effects of anti-inflammation, improving immunity, antibacterial and antiviral, anti-osteoporosis, lipid-lowering, hypoglycemic, anti-tumor, neuroprotection, anti-aging, etc.

[0017] Coptis chinensis: It is the dried rhizome of Coptis chinensis, Coptis triangularis or Coptis chinensis of the Ranunculaceae family. It is cold in nature and bitter in taste. It enters the heart, spleen, stomach, liver, gallbladder and large intestine meridians. It has the functions of clearing away heat and dampness, purging fire and detoxifying. It is used for damp-heat fullness, vomiting and acid regurgitation, diarrhea, jaundice, high fever and coma, hyperactivity of heart fire, restlessness and insomnia, palpitations, vomiting and bleeding due to blood heat, red eyes, toothache, thirst, pain, swelling and furunculosis; it is used externally to treat eczema, wet sores and pus in the ear canal. Modern research shows that the main components include coptis chinensis, berberine, epiberberine, palmatine, lignans, flavonoids, scopoletin, protocatechuic acid, ferulic acid, chlorogenic acid, o-diphenol, lactic acid, vanillic acid, gentisic acid, volatile oils, polysaccharides, sterols, amino acids and trace elements. It has anti-arrhythmia, anti-heart failure, myocardial protection and anti-platelet aggregation, blood pressure lowering, anti-cerebral ischemia / hemorrhagic damage, hypoglycemic, anti-inflammatory, anti-tumor, antibacterial and antiviral effects.

[0018] Evodia rutaecarpa: It is the dried nearly mature fruit of Evodia rutaecarpa, Evodia rutaecarpa or Evodia rutaecarpa of the Rutaceae family. It is hot in nature, pungent and bitter in taste; it is slightly toxic. It enters the liver, spleen, stomach and kidney meridians. It has the functions of dispelling cold and relieving pain, lowering adverse qi and stopping vomiting, and assisting yang and stopping diarrhea. It is used for headache of Jueyin meridian, abdominal pain caused by cold hernia, beriberi caused by cold and dampness, abdominal pain during menstruation, abdominal distension and pain, vomiting and acid swallowing, and diarrhea at dawn. Modern research shows that the main components include indole, quinolone, furanquinoline, acridine alkaloids, bitter elements, volatile oils, terpenes, isopentenyl flavonoid flavonoid compounds, coumarins, steroids (β-sitosterol), lignin, polysaccharides, anthocyanins, various amino acid compounds, trace elements and fatty acid compounds, etc. It has the functions of strengthening the heart, protecting the heart, anti-arrhythmia, lowering blood pressure, prolonging the time of bleeding and thrombosis, inhibiting abnormal fermentation in the intestine, promoting uterine contraction, analgesic and anti-inflammatory, and anti-tumor.

[0019] Wulingzhi: It is the dried feces of the orange-footed flying squirrel of the family Sciuridae. It tastes bitter and sweet, and is warm in nature. It enters the liver and spleen meridians. It has the functions of promoting blood circulation and relieving pain, removing blood stasis and stopping bleeding, and removing stagnation and detoxification. Modern research shows that the main components include protocatechuic acid, uracil, catechol, benzoic acid, wulingzhi acid, 3-carene-9,10-dihydroxy acid, etc. It has the functions of enhancing immunity, anti-inflammatory, anti-ulcer, anti-fibrinolysis, and anti-cerebral ischemia.

[0020] Raw Typhae Pollen: It is the dried pollen of Typha aquatica, Typha orientalis or plants of the same genus in the Typhaceae family. It is mild in nature and sweet in taste. It enters the liver and pericardium meridians. It has the functions of stopping bleeding, removing blood stasis, and relieving stranguria. It is used for hematemesis, epistaxis, hemoptysis, metrorrhagia, traumatic bleeding, amenorrhea, dysmenorrhea, stabbing pain in the chest and abdomen, swelling and pain due to falls, and painful stranguria due to blood. Modern research shows that the main components are naringenin, quercetin, typhane glycosides, organic acids, polysaccharides, tannins, steroids, and alkanes. It has the functions of anticoagulation, improving blood rheology, inhibiting platelet aggregation, protecting the myocardium, regulating lipid metabolism, anti-atherosclerosis, regulating sugar metabolism, anti-inflammatory, and anti-oxidant free radicals.

[0021] Clinical Research

[0022] A total of 120 outpatients who visited the Third Affiliated Hospital of Beijing University of Chinese Medicine from June 2019 to January 2020 were selected. All of them were diagnosed with erosive gastritis with excessive stomach fire syndrome by gastroscopy within 1 week and were in line with the "Chinese Consensus on Chronic Gastritis" formulated by the Gastroenterology Branch of the Chinese Medical Association in Shanghai in 2017. Those diagnosed as HP-negative by the 13C-urea breath test (13C-UBT) were directly included in the group; for those who were HP-positive, they were included in the group after 2 weeks of quadruple eradication of HP treatment. They were divided into two groups according to the random number table method. The subjects were randomly divided into a treatment group of 60 cases and a control group of 60 cases. There were no significant differences between the two groups of patients in terms of age, gender, disease course, and TCM syndrome scores. Specifically, using the method of random, positive drug parallel control design, 120 patients with erosive gastritis with excessive stomach fire syndrome were randomly divided into a treatment group and a control group. The control group was given omeprazole enteric-coated tablets (Shandong Xinsdai Pharmaceutical Co., Ltd., national drug approval number: H20044871), 40 mg bid po and rebamipide (Zhejiang Yuanlijian Pharmaceutical Co., Ltd., national drug approval number: H20010015), 0.1 g tid po for western medicine treatment. The treatment group was given the drug composition obtained in Example 1 of the present invention for treatment. Both groups took 7 days as 1 course of treatment and were treated continuously for 4 courses. The curative effect evaluation took the total TCM syndrome score as the main index and the single symptom scores (stomachache, abdominal distension, acid reflux, etc.) as the secondary indexes, and chi-square test was used for statistical analysis. The results showed that the total effective rate of the treatment group reached 91.67%, which was significantly higher than 78.33% of the control group (P<0.05). In terms of symptom improvement, the symptoms such as stomachache, abdominal distension, and acid reflux in both groups of patients were alleviated compared with before treatment. The treatment group had significantly better improvement effects on symptoms such as thirst, hiccups, heartburn, and polyphagia than the control group (P<0.05). After half a year of follow-up, it was found that the recurrence rate of the treatment group was only 6.67%, which was significantly lower than 20% of the control group (P<0.05), highlighting the long-term advantage of traditional Chinese medicine treatment. No adverse reactions were seen in all cases. This research "Clinical Research on Treating Erosive Gastritis with Excessive Stomach Fire Syndrome by Modified Qingwei Powder" has been approved by the Ethics Committee of the Third Affiliated Hospital of Beijing University of Chinese Medicine.

[0023] Typical clinical cases

[0024] Case 1:

[0025] Patient A, female, 62 years old. She visited the doctor in February 2023. The main complaint was stomach distension and pain for more than 1 year. One year ago, due to emotional distress and spicy diet, she developed stomach pain and distension, which were aggravated after meals. Occasionally, there was acid reflux and heartburn, dry mouth and bitter taste, no bad breath, formed stools, dry in texture, once a day. The tongue was red, the tongue coating was yellow, and the pulse was string-taut and slippery. Gastroscopy showed: chronic superficial gastritis with erosion. Hp (-). The traditional Chinese medicine diagnosis was stomachache (syndrome of excessive fire of stomach meridian). Western medicine diagnosis: erosive gastritis. After taking the prescription of the present invention for 7 doses, the stomach pain and distension were relieved. After taking 14 doses continuously, the stomach pain, acid reflux and heartburn disappeared, the bitter taste was relieved, and there was occasional stomach distension. Subsequently, the prescription of the present invention was used as the basis for addition and subtraction to consolidate the curative effect, and now she has recovered.

[0026] Case 2:

[0027] Patient B, male, 60 years old. He visited the doctor in October 2024. The main complaint was stomach pain and distension for more than 3 years, aggravated for more than 1 year. Three years ago, due to excessive drinking, he had occasional stomach pain and distension. One year ago, due to improper diet, the stomach pain and distension were aggravated. It was aggravated after every meal, with acid reflux and heartburn, dry mouth and bitter taste, bad breath, unformed stools, sticky in texture, 1-2 times a day. The tongue was red, the tongue coating was yellow and greasy, and the pulse was slippery and rapid. Gastroscopy showed: chronic superficial gastritis with erosion. Hp (-). The traditional Chinese medicine diagnosis was stomachache (syndrome of excessive fire of stomach meridian). Western medicine diagnosis: erosive gastritis. After taking the prescription of the present invention for 14 doses, the stomach pain and distension were relieved, the stools had become formed, and there was occasional sticking to the wall of the intestine, once a day. After taking 28 doses, the stomach pain, bitter taste and bad breath disappeared, and there was occasional stomach distension and dry mouth. The stools were formed, with good texture, once a day. Subsequently, the prescription of the present invention was used as the basis for addition and subtraction to consolidate the curative effect, and now he has recovered. Detailed implementation mode

[0028] The present invention will be further described below in conjunction with embodiments. The "parts" mentioned in the present invention refer to the weight parts of dried Chinese medicinal materials, and each part corresponds to 1 gram.

[0029] Embodiment 1

[0030] Weigh 15 parts of Angelica sinensis, 15 parts of Rehmannia glutinosa, 10 parts of Cortex Moutan, 10 parts of Rhizoma Cimicifugae, 10 parts of Coptis chinensis, 3 parts of Evodia rutaecarpa, 10 parts of Faeces Trogopterori, and 15 parts of Pollen Typhae. The proportion of each medicinal material in the composition should meet: the weight ratio of Coptis chinensis to Evodia rutaecarpa is 10:3.

[0031] Preparation method:

[0032] The total weight of the medicinal materials is soaked in 8 times the amount of purified water for 30 minutes, boiled with strong fire until 100 °C, then turned to slow fire to keep it boiling gently for 40 minutes, and filtered to obtain the first decoction; the medicinal residues are decocted with 6 times the amount of water for 30 minutes, and the filtrates are combined and concentrated to a relative density of 1.10 - 1.15 (60 °C).

[0033] Embodiment 2

[0034] 10 - 30 parts of Angelica sinensis, 10 - 30 parts of Rehmannia glutinosa, 5 - 15 parts of Cortex Moutan, 5 - 15 parts of Rhizoma Cimicifugae, 5 - 20 parts of Rhizoma Coptidis, 1 - 10 parts of Evodia rutaecarpa, 5 - 20 parts of Faeces Trogopterori, 10 - 30 parts of Pollen Typhae. The proportion of each medicinal material in the composition should meet the requirement that the weight ratio of Rhizoma Coptidis to Evodia rutaecarpa is 10:3.

[0035] The preparation steps are the same as those in Example 1.

[0036] Example 3

[0037] 12 - 20 parts of Angelica sinensis, 12 - 20 parts of Rehmannia glutinosa, 8 - 12 parts of Cortex Moutan, 5 - 10 parts of Rhizoma Cimicifugae, 5 - 15 parts of Rhizoma Coptidis, 2 - 5 parts of Evodia rutaecarpa, 8 - 12 parts of Faeces Trogopterori, 12 - 18 parts of Pollen Typhae. The proportion of each medicinal material in the composition should meet the requirement that the weight ratio of Rhizoma Coptidis to Evodia rutaecarpa is 10:3.

[0038] The preparation steps are the same as those in Example 1.

[0039] The above content is only an illustrative example of how to implement the present invention, rather than the protection scope of the present invention. Those skilled in the art of this technology make various modifications or supplements to the described specific embodiments or use similar ways to replace them. As long as they do not deviate from the structure of the invention or exceed the scope defined by this claim book, they should fall within the protection scope of the present invention.

Claims

1. A Chinese medicine composition for treating erosive gastritis due to excessive stomach fire, characterized in that The composition is prepared from the following Chinese medicines in parts by weight, wherein the "parts" in the present invention refer to the parts by weight of dry Chinese medicines, and each part corresponds to 1 gram: 10-30 parts of angelica, 10-30 parts of raw rehmannia, 5-15 parts of peony bark, 5-15 parts of cimicifuga, 5-20 parts of coptis root, 1-10 parts of evodia rutaecarpa, 5-20 parts of quinquefolius, and 10-30 parts of raw pollen. The proportion of each medicinal material in the composition must meet the following requirements: the weight ratio of coptis root to evodia rutaecarpa is 10:

3.

2. A Chinese medicine composition for treating erosive gastritis due to excessive stomach fire according to claim 1, characterized in that The composition is prepared from the following Chinese medicines in parts by weight, wherein the "parts" in the present invention refer to the parts by weight of dry Chinese medicines, and each part corresponds to 1 gram: 12-20 parts of angelica, 12-20 parts of raw rehmannia, 8-12 parts of peony bark, 5-10 parts of cimicifuga, 5-15 parts of coptis root, 2-5 parts of evodia rutaecarpa, 8-12 parts of quinquefolius, and 12-18 parts of raw pollen. The proportion of each medicinal material in the composition must meet the following requirements: the weight ratio of coptis root to evodia rutaecarpa is 10:

3.

3. A Chinese medicine composition for treating erosive gastritis due to excessive stomach fire according to claim 1, characterized in that The composition is prepared from the following Chinese medicines in parts by weight, wherein the "parts" in the present invention refer to the parts by weight of dry Chinese medicines, and each part corresponds to 1 gram: 15 parts of angelica, 15 parts of raw rehmannia, 10 parts of peony bark, 10 parts of cimicifuga, 10 parts of coptis root, 3 parts of evodia rutaecarpa, 10 parts of truncatum, and 15 parts of raw pollen. The proportion of each medicinal material in the composition must meet the following requirements: the weight ratio of coptis root to evodia rutaecarpa is 10:3.