A traditional Chinese medicine composition and hot compress for postoperative rehabilitation after gynecological laparoscopy.

Abstract

This invention provides a traditional Chinese medicine composition and a hot compress for postoperative rehabilitation after gynecological laparoscopic surgery, belonging to the technical field of traditional Chinese medicine hot compresses. The traditional Chinese medicine composition of this invention comprises the following raw materials by weight: 4-6 parts of Artemisia argyi, 6-10 parts of vinegar-processed Corydalis yanhusuo, 12-18 parts of Clematis chinensis, 20-30 parts of processed Evodia rutaecarpa, and 6-10 parts of stir-fried Atractylodes macrocephala. The traditional Chinese medicine composition can be further mixed with 250-350 parts of coarse salt to prepare a hot compress. When applied to patients after gynecological laparoscopic surgery, the traditional Chinese medicine composition and hot compress of this invention can significantly shorten the time to the first bowel sound and first flatus, reduce the incidence of postoperative abdominal distension, especially reducing the risk of severe abdominal distension; at the same time, it effectively relieves shoulder and neck pain, improving postoperative comfort and patient satisfaction.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine hot compress technology, and particularly relates to a traditional Chinese medicine composition and hot compress for postoperative rehabilitation of gynecological laparoscopic surgery. Background Technology

[0002] Gynecological laparoscopic surgery, with its advantages of being minimally invasive, causing little trauma, requiring a short postoperative hospital stay, and allowing for rapid recovery, has been widely used in the clinical treatment of gynecological diseases such as uterine fibroids, ovarian cysts, and fallopian tube lesions. However, this surgery requires the establishment of a CO (cooperative medical record). 2 Pneumoperitoneum for obtaining the operational field of view, CO 2 Gas can easily irritate the peritoneum and phrenic nerve. In addition, the general anesthetic drugs inhibit gastrointestinal motility. Postoperative complications such as delayed recovery of gastrointestinal function, abdominal distension, and abdominal pain are common among patients. Some patients may also experience discomfort related to gas abdomen, such as shoulder and neck pain. This not only reduces postoperative comfort but also prolongs the recovery period and increases hospitalization costs.

[0003] Current clinical interventions for the above-mentioned postoperative problems have significant limitations: routine nursing care can only provide basic support such as vital sign monitoring and dietary guidance, and cannot actively promote the recovery of gastrointestinal function or relieve pain; although prokinetic drugs can improve abdominal distension, they have side effects such as nausea and diarrhea, and have no therapeutic effect on shoulder and neck pain; existing traditional Chinese medicine hot compresses are mostly single-component, with limited efficacy and insufficient targeting, making it difficult to meet the clinical needs of rapid recovery after gynecological laparoscopic surgery (ERAS).

[0004] Therefore, the development of a traditional Chinese medicine hot compress that is scientifically formulated, effective, safe, and non-invasive, and can simultaneously promote gastrointestinal motility, relieve abdominal distension and pain, and improve shoulder and neck pain, has become an urgent need in the field of gynecological laparoscopic surgery rehabilitation. Summary of the Invention

[0005] In view of this, the purpose of the present invention is to provide a traditional Chinese medicine composition and hot compress for postoperative rehabilitation of gynecological laparoscopic surgery, which can effectively promote postoperative gas expulsion and relieve shoulder, neck and abdominal pain.

[0006] To achieve the above-mentioned objectives, the present invention provides the following technical solution: A traditional Chinese medicine composition for postoperative rehabilitation after gynecological laparoscopic surgery, comprising the following raw materials by weight: 4-6 parts of Artemisia argyi, 6-10 parts of Corydalis yanhusuo (processed with vinegar), 12-18 parts of Clematis armandii, 20-30 parts of processed Evodia rutaecarpa, and 6-10 parts of Atractylodes macrocephala (stir-fried with wheat bran).

[0007] Preferably, the raw materials include the following by weight: 5 parts Artemisia argyi, 8 parts Corydalis yanhusuo (processed with vinegar), 15 parts Clematis armandii, 25 parts Evodia rutaecarpa (processed with wheat bran), and 8 parts Atractylodes macrocephala (stir-fried with wheat bran).

[0008] The present invention also provides the application of the above-mentioned traditional Chinese medicine composition in the preparation of a hot compress for postoperative rehabilitation after gynecological laparoscopic surgery.

[0009] This invention provides a hot compress for postoperative rehabilitation of gynecological laparoscopic surgery, comprising the above-mentioned traditional Chinese medicine composition and 250-350 parts of coarse salt.

[0010] Preferably, the particle size of the coarse salt is 10-15 mm.

[0011] Preferably, it also includes an inner non-woven fabric liner bag and an outer cotton or linen bag.

[0012] Preferably, the weight of a single bag is 300~410g.

[0013] The present invention also provides a method for preparing the above-mentioned hot compress, comprising the following steps: pulverizing each raw material of the traditional Chinese medicine composition, mixing it evenly with the coarse salt, filling it into a non-woven inner bag, and then filling the inner bag into a cotton and linen bag.

[0014] Preferably, the particle size of the pulverized material is 20-60 mesh.

[0015] Compared with the prior art, the present invention has the following beneficial effects: The herbal composition and hot compress of this invention, when applied to patients after gynecological laparoscopic surgery, can significantly shorten the time to the first bowel sound and anal flatus, reduce the incidence of postoperative abdominal distension, and especially reduce the risk of severe abdominal distension; at the same time, it can effectively relieve shoulder and neck pain, improve postoperative comfort, and the patient satisfaction and recommendation rate are significantly higher than those of the control group.

[0016] The application of the herbal composition and hot compress of this invention can effectively improve various discomfort symptoms in patients after gynecological laparoscopic surgery, promote rapid postoperative recovery, and is significantly superior to conventional nursing care without the use of hot compress. It has clear clinical efficacy advantages, good safety and clinical promotion value, and provides a practical and effective external treatment technology solution for gynecological laparoscopic surgery recovery. Detailed Implementation

[0017] This invention provides a traditional Chinese medicine composition for postoperative rehabilitation of gynecological laparoscopic surgery, comprising the following raw materials by weight: 4-6 parts of Artemisia argyi, 6-10 parts of Corydalis yanhusuo (processed with vinegar), 12-18 parts of Clematis armandii, 20-30 parts of processed Evodia rutaecarpa, and 6-10 parts of Atractylodes macrocephala (stir-fried with wheat bran).

[0018] In this invention, the functions of each active pharmaceutical ingredient are analyzed as follows: Artemisia argyi: It warms the meridians and stops bleeding, dispels cold and relieves pain, and is especially good at warming the lower abdomen. It is the principal ingredient. The optimal amount of Artemisia argyi is 5 parts.

[0019] Processed Evodia rutaecarpa: It dispels cold and relieves pain, soothes the liver and regulates qi, and dries dampness. Its nature is hot, and it is good at warming the middle jiao, dispelling cold, and relieving pain, thus enhancing the warming and unblocking effect of the principal herb. The optimal amount of processed Evodia rutaecarpa is 25 parts.

[0020] Vinegar-processed Corydalis: Promotes blood circulation, regulates qi, and relieves pain. The analgesic effect is enhanced after processing with vinegar. The optimal amount of vinegar-processed Corydalis is 8 parts per portion.

[0021] Iron-wire Clematis: dispels wind and dampness, relaxes muscles and promotes blood circulation, relieves pain, and is mainly used to treat muscle spasms and pain, especially shoulder and neck muscle pain. The optimal amount of Iron-wire Clematis is 15 parts.

[0022] Stir-fried Atractylodes macrocephala: Strengthens the spleen and replenishes qi, dries dampness and promotes diuresis. Stir-frying enhances its spleen-strengthening and stomach-harmonizing effects, helps promote gastrointestinal motility, and restores qi circulation. The optimal amount of stir-fried Atractylodes macrocephala is 8 parts.

[0023] The present invention also provides the application of the above-mentioned traditional Chinese medicine composition in the preparation of a hot compress for postoperative rehabilitation after gynecological laparoscopic surgery.

[0024] This invention provides a hot compress for postoperative rehabilitation of gynecological laparoscopic surgery, comprising the above-mentioned traditional Chinese medicine composition and 250-350 parts of coarse salt.

[0025] Coarse bark salt: Clears heat and cools the blood; also serves as an excellent heat storage medium, releasing heat evenly and slowly to maintain medicinal efficacy. The preferred coarse bark salt content is 300 parts, with a further preferred particle size of 10-15 mm.

[0026] In this invention, the hot pack preferably includes an inner non-woven fabric liner bag and an outer cotton and linen bag. The double-layer packaging improves the heat preservation of the hot pack. More preferably, the weight of a single bag is 300~410g.

[0027] The present invention also provides a method for preparing the above-mentioned hot compress, comprising the following steps: pulverizing each raw material of the above-mentioned traditional Chinese medicine composition, mixing it evenly with coarse salt, filling it into a non-woven inner bag, and then filling the inner bag into a cotton and linen bag.

[0028] In this invention, the particle size of each raw material is preferably 20-60 mesh, more preferably 30-50 mesh, and even more preferably 40 mesh. A suitable particle size is beneficial for the release of the active ingredients.

[0029] As one possible implementation method, the hot compress of the present invention is used as follows: When using, place the hot compress in a microwave oven or steamer and heat it to 40~50℃. After taking it out, apply it to the shoulders, neck, abdomen or painful area for 20~30 minutes each time, once a day.

[0030] The technical solutions provided by the present invention will be described in detail below with reference to the embodiments, but they should not be construed as limiting the scope of protection of the present invention.

[0031] Example 1 A hot compress for postoperative rehabilitation after gynecological laparoscopic surgery, the formula and preparation method are as follows: Chinese herbal composition (parts by weight): Artemisia argyi 5 parts, Corydalis yanhusuo (processed with vinegar) 8 parts, Clematis armandii 15 parts, Evodia rutaecarpa (processed) 25 parts, Atractylodes macrocephala (stir-fried with wheat bran) 8 parts; Additional ingredients: 300 parts coarse salt, with a particle size of 10-15mm; Preparation: The raw material is pulverized to 40 mesh, mixed with coarse salt, and packed into a non-woven fabric inner bag + cotton and linen bag, with a single bag weighing 360g.

[0032] Example 2 A hot compress for postoperative rehabilitation after gynecological laparoscopic surgery, the formula and preparation method are as follows: Traditional Chinese medicine composition (parts by weight): Artemisia argyi 4 parts, Corydalis yanhusuo (processed with vinegar) 6 parts, Clematis armandii 12 parts, Evodia rutaecarpa (processed) 20 parts, Atractylodes macrocephala (stir-fried with wheat bran) 6 parts; Additional ingredients: 250 parts of coarse salt, with a particle size of 10-15mm; Preparation: The raw material is pulverized to 20 mesh, mixed with coarse salt, and packed into a non-woven fabric inner bag + cotton and linen bag, with a single bag weighing 310g.

[0033] Example 3 A hot compress for postoperative rehabilitation after gynecological laparoscopic surgery, the formula and preparation method are as follows: Traditional Chinese medicine composition (parts by weight): Artemisia argyi 6 parts, Corydalis yanhusuo (processed with vinegar) 10 parts, Clematis armandii 18 parts, Evodia rutaecarpa (processed with wheat bran) 30 parts, Atractylodes macrocephala (stir-fried with wheat bran) 10 parts; Additional ingredients: 350 parts of coarse salt, with a particle size of 10-15mm; Preparation: The raw material is pulverized to 60 mesh, mixed with coarse salt, and packed into a non-woven fabric inner bag + cotton and linen bag, with a single bag weighing 410g.

[0034] Example 4 A hot compress for postoperative rehabilitation after gynecological laparoscopic surgery, the formula and preparation method are as follows: Traditional Chinese medicine composition (parts by weight): Artemisia argyi 4.5 parts, Corydalis yanhusuo (processed with vinegar) 7 parts, Clematis armandii 14 parts, Evodia rutaecarpa (processed) 22 parts, Atractylodes macrocephala (stir-fried with wheat bran) 7 parts; Additional ingredients: 280 parts of coarse salt, with a particle size of 10-15mm; Preparation: The raw material is pulverized to 30 mesh, mixed with coarse salt, and packed into a non-woven fabric inner bag + cotton and linen bag, with a single bag weighing 340g.

[0035] Example 5 A hot compress for postoperative rehabilitation after gynecological laparoscopic surgery, the formula and preparation method are as follows: Traditional Chinese medicine composition (parts by weight): Artemisia argyi 5.5 parts, Corydalis yanhusuo (processed with vinegar) 9 parts, Clematis armandii 16 parts, Evodia rutaecarpa (processed) 28 parts, Atractylodes macrocephala (stir-fried with wheat bran) 9 parts; Additional ingredients: 320 parts of coarse salt, with a particle size of 10-15mm; Preparation: The raw material is pulverized to 50 mesh, mixed with coarse salt, and packed into a non-woven fabric inner bag + cotton and linen bag, with a single bag weighing 380g.

[0036] Test case 1. Research subjects and grouping Forty patients who underwent gynecological laparoscopic surgery were selected. All cases were admitted to Peking Union Medical College Hospital, Chinese Academy of Medical Sciences from July 2025 to November 2025. Inclusion criteria were: ① meeting the indications for gynecological laparoscopic surgery and performing the procedure in accordance with regulations; ② having stable vital signs after surgery and no serious organic lesions of the heart, liver, or kidneys; ③ having no history of allergy to traditional Chinese medicine hot compresses and having good compliance.

[0037] Patients were randomly divided into an observation group and a control group, with 20 patients in each group. The age of the patients in both groups ranged from 32 to 65 years, with a mean age of 45.2 ± 8.7 years.

[0038] Surgical procedures included: myomectomy (12 cases), ovarian cystectomy (18 cases), and fallopian tube surgery (10 cases).

[0039] The operation time ranged from 60 to 150 minutes, with an average of 95 ± 22 minutes. There was no statistically significant difference compared with baseline data. P (>0.05), making them comparable.

[0040] 2. Intervention methods 2.1 Control Group Only routine postoperative care for gynecological laparoscopy was performed, including: ① lying supine without a pillow for 6 hours postoperatively, monitoring vital signs, abdominal incision and vaginal bleeding; ② fasting for 6 hours postoperatively, followed by transition to a liquid diet based on tolerance; ③ instructing patients to turn over and move in bed within 24 hours postoperatively, and to get out of bed and walk as soon as possible after 24 hours; ④ routine symptomatic treatment such as fluid replacement, anti-infection, and analgesia were given, without using any auxiliary means to promote the recovery of gastrointestinal function (such as medication, physical therapy, external application of traditional Chinese medicine, etc.).

[0041] 2.2 Observation Group In addition to the routine nursing care of the control group, the traditional Chinese medicine hot compress intervention of Example 1 was added. This hot compress is designed to address the core problems of postoperative abdominal distension and difficulty in passing gas, as well as shoulder, neck and abdominal pain, and integrates heat therapy, drug therapy and saline therapy.

[0042] Timing of use: Begin on the first day after surgery (after the patient has recovered from anesthesia and their vital signs are stable).

[0043] Instructions for use: Place the hot compress in a microwave oven or steamer and heat it to 40-50℃. After removing it, apply the hot compress to the abdomen (avoiding surgical incisions) and neck and shoulders for 20-30 minutes each time, once a day, for 1-3 consecutive days.

[0044] Precautions: Monitor skin temperature during the hot compress process to avoid burns. Discontinue use immediately if skin redness, itching, or other discomfort occurs.

[0045] 3. Observation Indicators and Evaluation Methods 3.1 Core efficacy indicators Postoperative gastrointestinal function recovery related to: ① Time to first flatus (time from the end of surgery to the first flatus, accurate to 0.5 hours); ② Time to first bowel sound recovery (time from the end of surgery to the first bowel sound heard on auscultation); ③ Postoperative abdominal distension degree (using the NCCN abdominal distension grading standard: Grade 0 - no abdominal distension; Grade I - mild abdominal distension, no discomfort; Grade II - moderate abdominal distension, mild abdominal pain; Grade III - severe abdominal distension, significant abdominal pain, abdominal bloating).

[0046] Postoperative discomfort relief: ① Neck and shoulder pain level (using the Visual Analogue Scale (VAS), 0 points - no pain, 10 points - severe pain, assessed on the 3rd day after surgery); ② Postoperative comfort level (self-made 10-point scale, 1 point - very uncomfortable, 10 points - very comfortable, assessed on the 3rd day after surgery).

[0047] 3.2 Satisfaction Evaluation A self-designed satisfaction questionnaire was used to conduct the survey on the 3rd day after surgery. The satisfaction level was divided into four levels: very satisfied, satisfied, neutral, and dissatisfied. The satisfaction rate was calculated as (number of very satisfied cases + number of satisfied cases) / total number of cases × 100%.

[0048] 3.3 Statistical Methods SPSS 22.0 software was used for analysis. Quantitative data were expressed as (x±s), and t-tests were used for comparisons between groups. Categorical data were expressed as rates (%), and chi-square tests were used for comparisons between groups. 2 Test; use the rank-sum test for ordinal data. P <0.05 indicates a statistically significant difference.

[0049] 4. Test Results 4.1 Comparison of Gastrointestinal Function Recovery As shown in Table 1, the time to first bowel sound recovery and first flatus passage after surgery were significantly shorter in the observation group than in the control group, and the differences between the groups were statistically significant. P <0.001); the incidence of postoperative abdominal distension in the observation group was only 20.0%, significantly lower than 60.0% in the control group ( P <0.01), and no cases of grade III severe abdominal distension were observed, while 3 cases of severe abdominal distension were observed in the control group. The difference between the groups was statistically significant. P <0.05), indicating that the hot compress of the present invention can effectively accelerate the recovery of gastrointestinal function after gynecological laparoscopic surgery, significantly reduce the incidence of abdominal distension and avoid the occurrence of severe abdominal distension.

[0050] Table 1 Comparison of postoperative gastrointestinal function recovery between the two groups of patients

[0051] 4.2 Comparison of postoperative discomfort relief As shown in Table 2, on the 3rd postoperative day, the VAS score for neck and shoulder pain in the observation group was significantly lower than that in the control group, while the postoperative comfort score was significantly higher in the observation group. Both of these indicators showed highly statistically significant differences between the groups. P <0.001), indicating that the hot compress of the present invention can effectively relieve shoulder and neck pain after gynecological laparoscopic surgery and greatly improve the patient's postoperative comfort.

[0052] Table 2 Comparison of postoperative discomfort relief between the two groups of patients

[0053] 4.3 Comparison of Satisfaction Levels Control group: 8 cases were very satisfied, 7 cases were satisfied, 3 cases were neutral, and 2 cases were dissatisfied, with a satisfaction rate of 75.0% and a recommendation rate of 65.0%.

[0054] Observation group: 16 cases were very satisfied, 4 cases were satisfied, the satisfaction rate was 100%, and the recommendation rate was 100%.

[0055] Between-group comparison: x 2 =5.174, P =0.023 < 0.05, the difference is statistically significant.

[0056] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A traditional Chinese medicine composition for postoperative rehabilitation after gynecological laparoscopic surgery, characterized in that, The raw materials include the following ingredients by weight: 4-6 parts Artemisia argyi, 6-10 parts Corydalis yanhusuo (processed with vinegar), 12-18 parts Clematis armandii, 20-30 parts Evodia rutaecarpa (processed with wheat bran), and 6-10 parts Atractylodes macrocephala (stir-fried with wheat bran).

2. The traditional Chinese medicine composition according to claim 1, characterized in that, The raw materials include the following ingredients by weight: 5 parts Artemisia argyi, 8 parts Corydalis yanhusuo (processed with vinegar), 15 parts Clematis armandii, 25 parts Evodia rutaecarpa (processed with wheat bran), and 8 parts Atractylodes macrocephala (stir-fried with wheat bran).

3. The use of the traditional Chinese medicine composition according to claim 1 or 2 in the preparation of a hot compress for postoperative rehabilitation after gynecological laparoscopic surgery.

4. A heated compress for postoperative rehabilitation after gynecological laparoscopic surgery, characterized in that, It includes the traditional Chinese medicine composition as described in claim 1 or 2 and 250-350 parts of cobalt salt.

5. The hot wrap according to claim 4, characterized in that, The particle size of the large-grained salt is 10~15mm.

6. The hot wrap according to claim 4, characterized in that, It also includes an inner non-woven fabric liner bag and an outer cotton and linen bag.

7. The hot-pressed bread according to claim 4, characterized in that, Each bag weighs 300~410g.

8. A method for preparing the hot-pressed wrap according to any one of claims 4 to 7, characterized in that, Includes the following steps: The raw materials of the Chinese herbal medicine composition are pulverized, mixed evenly with the coarse salt, and then packed into a non-woven fabric inner bag. The inner bag is then packed into a cotton and linen bag.

9. The preparation method according to claim 8, characterized in that, The particle size of the pulverized material is 20-60 mesh.

Images