Electronic antiemetic device and system based on electrical stimulation

Abstract

The present invention discloses an electronic antiemetic device and system based on electrical stimulation, which relates to the technical field of electrotherapy antiemetics. The electronic antiemetic device includes: an electrode part, which is used to contact acupuncture points with antiemetic effects on the patient's body and apply non-invasive electrical stimulation; a current pulse generating part, which is electrically connected to the electrode part, and is used to generate controllable current pulses and transmit them to the aforementioned electrode part; an electrical stimulation control module, which is electrically connected to the current pulse generating part, and is used to control the operation of the current pulse generating part; wherein, it is configured to: receive an electrical stimulation instruction, and according to the interval time and current pulse parameters configured in the electrical stimulation instruction, control the current pulse generating part to intermittently enter the working state according to the interval time, and generate current pulses according to the aforementioned current pulse parameters. The present invention can prolong the time it takes for patients to develop tolerance through the intermittent electrical stimulation mode, and reduce manual adjustment.

Description

Technical Field

[0001] The present invention relates to the technical field of electrotherapy and antiemetics, and in particular to an electronic antiemetic device and system based on electrical stimulation. Background Art

[0002] Cancer patients often experience varying degrees of side effects such as nausea and vomiting after chemotherapy. Nausea and vomiting often lead to dietary disorders and dehydration in patients, and make patients fear chemotherapy, which seriously affects their quality of life and treatment compliance. Clinically, drug intervention is often used to treat vomiting. Currently, the antiemetic drugs used in clinical practice mainly include anti-parasympathetic drugs, antihistamines, dopamine receptor blockers (such as phenothiazines, butyrophenone, benzamide), 5-hydroxytryptamine receptor antagonists, and neurokinin-1 receptor antagonists such as aprepitant. However, there are many problems with the actual application of the above-mentioned antiemetic drugs, such as large side effects and difficulty in controlling the duration of action. In addition, some patients will develop resistance to antiemetic drugs, and the efficacy of the drugs will weaken as the use time of the drugs increases.

[0003] To address the above issues, existing technologies offer alternative treatments for chemotherapy and antiemetics. For example, Chinese patent application CN201410406445.X discloses a package for an antiemetic drug and a non-invasive electrical stimulation device, comprising: a first packaging unit containing the antiemetic drug and a second packaging unit containing the non-invasive electrical stimulation device, each with its own independent packaging space; the first packaging unit containing the antiemetic drug includes a clinically effective dose of tropisetron, and the second packaging unit containing the non-invasive electrical stimulation device includes a non-invasive electrical stimulation device that stimulates acupuncture points by outputting a weak current. The above-mentioned regimen prevents and treats nausea and vomiting in TACE patients through the antiemetic drug tropisetron combined with non-invasive electrical stimulation. The test results show that the overall efficacy of acupoint (Neiguan, Gongsun, and Hegu) electrical stimulation combined with tropisetron antiemetic treatment is better than that of the simple tropisetron antiemetic group. The combined group has a better antiemetic effect in the acute phase after TACE than the simple antiemetic group. Compared with other patients who only took antiemetic drugs and did not receive electrical stimulation intervention, the incidence of acute and delayed vomiting in patients who received the combined intervention measures was significantly lower, and their appetite and bowel movements were good after surgery, which is conducive to improving the quality of life. For example, Chinese patent application CN201910963622.7 discloses a low-frequency pulse antiemetic device with time control, which includes an MCU control for generating PWM signals to calculate and control the instructions of the various component modules of the electronic antiemetic device; a pulse generation system for generating low-frequency pulse signals to stimulate the higher centers of the cerebral cortex to stop vomiting; physical button control for controlling the power on and off of the electronic antiemetic device and adjusting the pulse signal intensity; an LCD scanning display system for displaying the working status of the electronic antiemetic device; a power supply system for powering the various modules of the electronic antiemetic device; and a USB charging port for charging the electronic antiemetic device via the USB port. The USB charging port is connected to the power supply system and also includes a duration control card system for the MCU control to control the low-frequency pulse output duration of the pulse generation system by reading data from the duration control card system. The above-mentioned existing solutions utilize the knowledge of acupuncture points in traditional Chinese medicine to alleviate or treat nausea and vomiting symptoms of chemotherapy patients by applying non-invasive electrical stimulation to acupuncture points with antiemetic effects. For example, the Neiguan acupoint on the wrist can stimulate the inner wrist meridians, transmitting energy upward to the vomiting center, affecting the transmission of nerve signals between the vagus nerve and the vomiting center, thereby alleviating vomiting and nausea. Simultaneously, this benign stimulation can stimulate the integration and adjustment functions of higher-level nerve centers, triggering a series of neural and humoral adjustments, and mobilizing the body's potential resistance to disease.

[0004] Currently, non-invasive acupoint stimulation using electrodes typically utilizes a single-acupoint dual-electrode configuration. This involves electrically connecting two electrodes (one positive and one negative) to a single acupoint, creating a localized closed circuit. During stimulation, the current flows along the shortest path between the two electrodes, allowing for a controlled stimulation range. This single-acupoint dual-electrode configuration offers advantages such as a clear current path, high safety, and strong anti-interference capabilities. Furthermore, the stimulation range can be adjusted by adjusting the spacing between the electrodes. However, in actual chemotherapy and antiemetic treatment, existing electrical stimulation protocols typically involve regular, continuous stimulation, which can lead to patient tolerance. This means that the perceived intensity of the electroacupuncture stimulation decreases over time, weakening the therapeutic effect. Traditional solutions limit the current intensity to the maximum tolerated by the patient and adjust the intensity based on their perception during treatment. This approach requires medical staff to promptly inquire about the patient's feelings and adjust the current intensity accordingly, significantly increasing their workload. Based on this, the existing technology has also proposed improvements, which are to set electric pulse intensity adjustment levels on the electronic antiemetic device - such as electric pulse output increase and decrease buttons for patients to adjust so as to reduce the workload of medical staff, but there is still the problem of patients' stimulation tolerance; moreover, manual adjustment of the instrument is still required during the treatment process. When the patient does not know how to operate manually (such as older people who find it difficult to remember how to operate the instrument) or cannot adjust manually (such as when the patient is very uncomfortable and finds it difficult to operate the instrument automatically), medical staff or relevant personnel are still required to provide assistance next to the instrument. Summary of the Invention

[0005] The purpose of the present invention is to overcome the shortcomings of the existing technology and provide an electronic antiemetic device and system based on electrical stimulation. The electronic antiemetic device provided by the present invention includes an interval electrical stimulation mode. After receiving the electrical stimulation instruction, the electrical stimulation control module can control the current pulse generating unit to enter the working state at intervals according to the interval time and current pulse parameters configured in the electrical stimulation instruction, and generate current pulses according to the aforementioned current pulse parameters. Compared with the existing regular continuous electrical stimulation, the interval electrical stimulation mode can prolong the time it takes for the patient to develop tolerance and reduce manual adjustment. Furthermore, the current pulse parameters and electrode spacing can be adjusted as the electrical treatment progresses.

[0006] To achieve the above objectives, the present invention provides the following technical solutions:

[0007] An electronic antiemetic device based on electrical stimulation, comprising:

[0008] an electrode portion, for contacting an acupuncture point having an antiemetic effect on a body part of a patient and applying non-invasive electrical stimulation;

[0009] a current pulse generating unit, electrically connected to the electrode unit, for generating a controllable current pulse and transmitting the current pulse to the electrode unit;

[0010] The electrical stimulation control module is electrically connected to the current pulse generating unit and is used to control the operation of the current pulse generating unit; wherein, the electrical stimulation control module is configured to: receive electrical stimulation instructions, and according to the interval time and current pulse parameters configured in the electrical stimulation instructions, control the current pulse generating unit to intermittently enter the working state according to the interval time, and generate current pulses according to the aforementioned current pulse parameters.

[0011] Further, it includes a user interaction unit for collecting the electrical stimulation mode and current pulse parameters selected by the user;

[0012] The electrical stimulation mode includes a continuous electrical stimulation mode and an interval electrical stimulation mode, each corresponding to a different electrical stimulation instruction;

[0013] The current pulse parameters include current pulse output duration and current pulse output intensity information; for the interval electrical stimulation mode, the current pulse output duration of the current pulse parameters includes the total working time, the number of working cycles and the working time of each working cycle.

[0014] Furthermore, the electrode portion includes two electrode structures for contacting the patient's skin, the first electrode structure being a positive electrode and the second electrode structure being a negative electrode;

[0015] The electrode structure is a plant root-mimicking structure, comprising a central main electrode and peripheral root electrodes located on the periphery of the main electrode; electrode drive motors are provided corresponding to the main electrode and the peripheral root electrodes, for driving the electrode heads of the corresponding electrodes to extend and retract, and the electrode drive motors are connected to and controlled by the electrical stimulation control module;

[0016] The electrical stimulation control module is configured to: when the working time of the current pulse generating unit arrives, control the electrode driving motor so that one electrode head of the first electrode structure and the second electrode structure contacts the skin as a working electrode, forming the positive electrode and negative electrode of the current loop respectively; and, during the application of electrical stimulation, control the electrode driving motor to drive the electrode heads on the first electrode structure and the second electrode structure to contact or move away from the skin to adjust the working electrodes, and adjust the electrode spacing for applying electrical stimulation by adjusting the working electrodes.

[0017] Furthermore, a working electrode dynamic adjustment control instruction is preset, and the working electrode dynamic adjustment control instruction is configured as follows: in an initial state, the main electrodes of the first electrode structure and the second electrode structure are used as working electrodes; when a preset electrode adjustment cycle arrives, the working electrode of the first electrode structure is adjusted to one of the peripheral root electrodes, and the working electrode of the second electrode structure remains the main electrode unchanged, waiting for the next electrode adjustment cycle to arrive; when the next electrode adjustment cycle arrives, the working electrode of the first electrode structure is restored to the main electrode, and the working electrode of the second electrode structure is adjusted to one of the peripheral root electrodes; when the electrode adjustment cycle ends, the working electrode adjustment is terminated and restored to the aforementioned initial state;

[0018] The electrical stimulation control module is configured to: execute the working electrode dynamic adjustment control instruction at least once when the current pulse generating unit is working; wherein, for the interval electrical stimulation mode, the working electrode dynamic adjustment control instruction is executed at least once per working cycle.

[0019] Furthermore, the electrical stimulation control module is further configured to: set different current pulse intensities for the main electrode and the peripheral root electrodes as working electrodes, so that the current pulse intensity when the main electrode is used as the working electrode is higher than the current pulse intensity when the peripheral root electrodes are used as working electrodes; and

[0020] When there are multiple peripheral root electrodes around the main electrode, the current pulse intensity of the outer root electrodes as working electrodes is higher than the current pulse intensity of the inner root electrodes as working electrodes.

[0021] Furthermore, the system further includes a patient status recognition module, which is in communication with the electrical stimulation control module and is configured to: collect physical status data of the patient during the electrical stimulation treatment, determine whether to continue to apply electrical stimulation based on the physical status data, and send an instruction to the electrical stimulation control module to end electrical stimulation when it is determined that electrical stimulation is not to be applied;

[0022] When receiving the aforementioned instruction to end electrical stimulation, the electrical stimulation control module controls the current pulse generating unit to enter a standby state.

[0023] The present invention also provides a chemotherapy and antiemetic treatment system, the system comprising:

[0024] Body support device, used for patients to sit or lie in a preset body posture;

[0025] The antiemetic treatment device includes the aforementioned electronic antiemetic device, which performs electrical stimulation treatment on one or more target acupuncture points on one or more body parts of the patient through the electrode part of the electronic antiemetic device.

[0026] Furthermore, the antiemetic treatment device further comprises a massage unit, wherein the massage unit comprises at least a central area and a peripheral area surrounding the central area;

[0027] The central area is provided with a first massage structure, and the massage head of the first massage structure is provided with an electrode portion of the electronic antiemetic device for electrically stimulating the target acupuncture point;

[0028] The peripheral area is provided with a second massage structure for surrounding the target acupuncture point position and massaging and stimulating the target acupuncture point from the outside to the inside or from the inside to the outside.

[0029] Furthermore, the massage head of the first massage structure is a multi-layer nested structure, including an inner layer, a first rotating layer sleeved outside the inner layer, and a second rotating layer sleeved outside the first rotating layer. The electrode portion is provided on the surface of the inner layer. The inner layer is capable of expansion and contraction adjustment relative to the first rotating layer, and the first rotating layer is capable of expansion and contraction adjustment relative to the second rotating layer.

[0030] The antiemetic treatment device is configured to: collect size information of the patient's body parts, determine the patient type based on the size information of the body parts, and then adjust the telescopic state of each layer of the massage head according to the patient type to adjust the contact area between the massage head and the patient's skin; wherein, when the patient is a child type, the inner layer and the first rotating layer are in an extended state and contact the patient's skin, electrical stimulation is performed through the inner layer, and skin massage is performed by rotating the first rotating layer; when the patient is an ordinary user type, the inner layer and the first rotating layer are in a retracted state, electrical stimulation is performed through the inner layer, and skin massage is performed by rotating the first rotating layer and the second rotating layer.

[0031] Furthermore, the massage stimulation is a contraction and expansion massage, and the second massage structure includes a massage head for achieving the contraction and expansion functions, and the massage head is provided with a liquid outlet hole;

[0032] It also includes a liquid delivery module, which includes a liquid delivery path set corresponding to the massage head, and the output end of the liquid delivery path is connected to the liquid outlet hole on the massage head: the liquid delivery module is configured to: when receiving a liquid discharge instruction sent by the anti-emetic treatment device, control the liquid delivery path to be connected to the liquid outlet hole of the corresponding massage head according to the massage head information in the liquid discharge instruction, and then deliver liquid to the corresponding massage head.

[0033] Due to the adoption of the above technical solution, the present invention has the following advantages and positive effects compared to the prior art, as an example: the electronic antiemetic device based on electrical stimulation includes an interval electrical stimulation mode. After receiving an electrical stimulation instruction, the electrical stimulation control module can control the current pulse generating unit to enter an intermittent working state according to the interval time and current pulse parameters configured in the electrical stimulation instruction, and generate current pulses according to the aforementioned current pulse parameters. Compared with the existing regular continuous electrical stimulation, the intermittent electrical stimulation mode can prolong the time it takes for patients to develop tolerance and reduce manual adjustments. Furthermore, the current pulse parameters can be adjusted as the electrical treatment progresses.

[0034] Furthermore, the electrode structure is designed to mimic the structure of plant roots: it includes a central main electrode and peripheral root electrodes located outside the main electrode; during electrical treatment, the peripheral root electrodes can be controlled to contact or move away from the skin to dynamically adjust the electrode spacing for applying electrical stimulation, and the dynamic electrode spacing can form a dynamic current stimulation range.

[0035] Furthermore, the present invention combines electrical stimulation therapy with acupoint massage. While electrical stimulation is applied to acupoints, massage stimulation is also applied via a massage unit to enhance the stimulation effect, further alleviating or treating vomiting symptoms in cancer chemotherapy patients. Specifically, the massage unit performing acupoint massage has been improved to enable different types of stimulation to be applied to the acupoint area and the surrounding area. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] Figure 1 The modular structure of the electronic antiemetic device based on electrical stimulation provided by the embodiment of the present invention Figure 1 .

[0037] Figure 2 The modular structure of the electronic antiemetic device based on electrical stimulation provided by the embodiment of the present invention Figure 2 .

[0038] Figure 3 A schematic diagram of an electrode structure that simulates a plant root structure provided by an embodiment of the present invention.

[0039] Figure 4 Schematic diagram of the electrode spacing between the positive and negative electrodes provided in an embodiment of the present invention.

[0040] Figure 5 Schematic diagram of the change in the electrode spacing between the positive and negative electrodes when the working electrode is adjusted according to an embodiment of the present invention.

[0041] Figure 6 This is a schematic diagram of the module structure of the chemotherapy and antiemetic treatment system provided in an embodiment of the present invention.

[0042] Figure 7A schematic diagram of the structure of a massage head including a central area and a peripheral area provided in an embodiment of the present invention.

[0043] Figure 8 This is a schematic diagram of the structure of a massage head with a multi-layer nested structure provided by an embodiment of the present invention.

[0044] Figure 9 A schematic diagram of the peripheral area structure including multiple massage ring belts provided in an embodiment of the present invention.

[0045] Description of reference numerals:

[0046] Electrode portion 100 , first electrode structure 110 , second electrode structure 120 , main electrodes 111 , 121 , and peripheral root electrodes 112 , 122 ;

[0047] Massage unit 200 , central area 210 , peripheral area 220 , inner layer 211 , first rotating layer 212 , second rotating layer 213 , first massage ring belt area 2201 , first massage ring belt area 2201 , second massage structure 221 . DETAILED DESCRIPTION

[0048] The following is a further detailed description of the electronic antiemetic device and system based on electrical stimulation disclosed in the present invention in conjunction with the accompanying drawings and specific embodiments. It should be noted that the technical features or combinations of technical features described in the following embodiments should not be considered isolated, and they can be combined with each other to achieve better technical effects. In the drawings of the following embodiments, the same reference numerals appearing in each drawing represent the same features or components, which can be applied to different embodiments. Therefore, once an item is defined in one drawing, it does not need to be further discussed in subsequent drawings.

[0049] It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not intended to limit the conditions under which the invention can be implemented. Any structural modification, change in proportional relationship, or adjustment of size should fall within the scope of the technical content disclosed in the invention without affecting the efficacy and purpose of the invention. The scope of the preferred embodiments of the present invention includes alternative implementations, in which the functions can be performed in a non-described or discussed order, including performing the functions in a substantially simultaneous manner or in a reverse order according to the functions involved, which should be understood by those skilled in the art of the art to which the embodiments of the present invention belong.

[0050] Technologies, methods, and apparatus known to persons of ordinary skill in the relevant art may not be discussed in detail, but where appropriate, such technologies, methods, and apparatus should be considered part of the specification. In all examples shown and discussed herein, any specific values ​​should be interpreted as merely exemplary and not limiting. Therefore, other examples of the exemplary embodiments may have different values.

[0051] In the description of the embodiments of this application, " / " represents "or," and "and / or" is used to describe the association relationship between associated objects, indicating that three possible relationships exist. For example, "A and / or B" represents the following three situations: A and B exist alone, B exists alone, and A and B exist at the same time. In the description of the embodiments of this application, "plurality" means two or more. Example

[0052] See also Figure 1 FIG. 1 shows an electronic antiemetic device based on electrical stimulation provided by the present invention. The electronic antiemetic device comprises an electrode portion, a current pulse generating portion and an electrical stimulation control module.

[0053] The electrode portion is used to contact acupuncture points on a patient's body that have an antiemetic effect and apply non-invasive electrical stimulation. Specifically, the electrode portion includes two electrode structures for contacting the patient's skin, with the first electrode structure being a positive electrode and the second electrode structure being a negative electrode.

[0054] The current pulse generating unit is electrically connected to the electrode unit and is used to generate a controllable current pulse and transmit it to the aforementioned electrode unit. Specifically, the current pulse generating unit can generate a periodic low-frequency bidirectional pulse wave to stimulate the acupuncture point nerves - for example, stimulate the nerve of the Neiguan acupoint and transmit it upward to the vomiting center, thereby regulating the signals that cause neurogenic vomiting and the vagus nerve signals traveling back and forth in the stomach, thereby alleviating the symptoms of vomiting, nausea, and anorexia. The current pulse generating unit can use an existing low-frequency electronic pulse instrument, which will not be described in detail here.

[0055] The electrical stimulation control module is electrically connected to the current pulse generating unit and is used to control the operation of the current pulse generating unit.

[0056] Among them, the electrical stimulation control module is configured to: receive electrical stimulation instructions, control the current pulse generation unit to enter the working state intermittently according to the interval time and current pulse parameters configured in the electrical stimulation instructions, and generate current pulses according to the aforementioned current pulse parameters.

[0057] See also Figure 2 As shown, the electronic antiemetic device may further include a user interaction unit for interacting with the user. Specifically, the user interaction unit may collect the electrical stimulation mode and current pulse parameters selected by the user.

[0058] The electrical stimulation modes include continuous and interval stimulation modes, each corresponding to a different electrical stimulation instruction. For continuous stimulation mode, the corresponding interval time is configured as 0; for interval stimulation mode, the corresponding interval time can be any non-zero value. Specifically, the interval time can be set by the system default or customized by the user.

[0059] The current pulse parameters include at least the current pulse output duration (s) and the current pulse output intensity (mA). For the interval electrical stimulation mode, the current pulse output duration of the current pulse parameters may include the total working time, the number of working cycles, and the working time of each working cycle.

[0060] In a specific implementation, the user interaction unit may include a first physical button or knob for selecting an electrical stimulation mode, and a second physical button or knob for rotating current pulse parameters. The user may use the physical buttons or knobs to configure the electrical stimulation mode and current pulse parameters for the patient's electrical stimulation treatment. Alternatively, the user interaction unit may include a graphical user interface (GUI), and the user's selected electrical stimulation mode and current pulse parameter information may be obtained through a stimulation parameter collection bar on the GUI.

[0061] In this embodiment, the intervals between the multiple working cycles can be the same or different. In a preferred embodiment, as the electrical stimulation treatment progresses, the intervals can be shortened according to a preset rule, and the working duration of the working cycle can be increased according to a preset rule. Furthermore, as the electrical stimulation treatment progresses, the current pulse output intensity can also be adjusted. For example, in the interval electrical stimulation mode, for multiple working cycles, the current pulse output intensity of the subsequent working cycle can be increased by a preset intensity ΔI (mA) compared to the current pulse intensity of the previous working cycle.

[0062] At this time, the current pulse parameters also include the initial value I0 of the current pulse output intensity and the current pulse intensity change value ΔI, which can be configured and selected by the user. Because the applied current pulse output intensity needs to be below the preset current pulse intensity safety value, after the user configures the number of working cycles, the initial value I0 of the current pulse output intensity, and the current pulse intensity change value ΔI, the corresponding current pulse output intensity termination value (i.e., the current pulse output intensity of the last working cycle) can be calculated. When the calculated current pulse output intensity termination value is greater than the aforementioned safety value, the user is reminded to reconfigure the parameters to ensure that the current pulse output intensity termination value is less than the aforementioned safety value. The safety value can be the system's default value or a personalized value set according to the patient.

[0063] In a preferred embodiment, the electrode structure is a plant root-mimicking structure, comprising a central main electrode and peripheral root electrodes located outside the main electrode.

[0064] See also Figure 3 As shown, taking the first electrode structure 110 as an example, a typical method of electrode structure that imitates plant root structure is illustrated: the first electrode structure 110 includes a central main electrode 111 and peripheral root electrodes 112 located on the periphery of the main electrode 111. A plurality of peripheral root electrodes 112 can be drawn out from a certain position or multiple positions on the main electrode 111 and then extend downward to form a plurality of root electrode heads. A main electrode head is also formed below the main electrode. The main electrode and the peripheral root electrodes are electrically connected, and the current pulse injected (or input) from the input end of the main electrode can be transmitted to the electrode heads of the electrodes below. The electrode heads are arranged on the shell of the electrode part. When viewed from the surface of the shell of the electrode part, a plurality of peripheral root electrode heads are arranged around the electrode head of the main electrode, see Figure 4 Preferably, the plurality of peripheral root electrode tips are arranged around the main electrode tip, and the peripheral root electrode tips are located at different positions on the periphery of the main electrode tip but are at equal distances from the center of the main electrode tip.

[0065] It should be noted that although Figure 3 and Figure 4 The example of four root electrodes arranged around a main electrode is shown here. However, those skilled in the art will appreciate that this arrangement is provided as an example and not as a limitation. The number of peripheral root electrodes can be increased or decreased as needed, such as 1, 2, 3, or 5. Furthermore, the distance and orientation angle of each root electrode relative to the main electrode can also be configured as needed.

[0066] The second electrode structure 120 has the same structure as the first electrode 110 , and will not be described in detail herein.

[0067] In this embodiment, an electrode drive motor, such as a micro telescopic motor, is further provided corresponding to the main electrode and the peripheral root electrode to drive the telescopic movement of the electrode head of the corresponding electrode. The electrode drive motor is connected to the electrical stimulation control module and receives control of the electrical stimulation control module. The extended electrode head can be flush with the surface of the electrode shell or protrude relative to the surface of the electrode shell to form a working electrode, while the retracted electrode head is housed in the electrode shell, such as in the concave groove of the shell, as a non-working electrode.

[0068] The electrical stimulation control module is configured to: when the working time of the current pulse generating unit arrives, control the electrode driving motor so that one electrode head of the first electrode structure and the second electrode structure contacts the skin as a working electrode, forming the positive electrode and negative electrode of the current loop respectively; and, during the application of electrical stimulation, control the electrode driving motor to drive the electrode heads on the first electrode structure and the second electrode structure to contact or move away from the skin to adjust the working electrodes, and adjust the electrode spacing for applying electrical stimulation by adjusting the working electrodes.

[0069] That is to say, during the operation of the current pulse generating unit, the electrical stimulation control module can be used to control the extension and retraction state of each electrode head to achieve dynamic adjustment of the working electrode, and during this period, one and only one positive electrode and one negative electrode contact the skin to form a circuit loop (the other electrodes are retracted into the shell and are in a stored state and will not contact the patient's skin).

[0070] Preferably, in this embodiment, a working electrode dynamic adjustment control instruction may be preset, and the working electrode dynamic adjustment control instruction is configured as follows: in the initial state, the main electrodes of the first electrode structure and the second electrode structure are used as working electrodes, and the corresponding electrode spacing is L0, see Figure 4 As shown; when the preset electrode adjustment cycle arrives, the working electrode of the first electrode structure is adjusted to one of the peripheral root electrodes, and the working electrode of the second electrode structure remains the main electrode unchanged, waiting for the next electrode adjustment cycle to arrive; when the next electrode adjustment cycle arrives, the working electrode of the first electrode structure is restored to the main electrode, and the working electrode of the second electrode structure is adjusted to one of the peripheral root electrodes. When the electrode adjustment cycle ends, the working electrode adjustment is ended and restored to the aforementioned initial state.

[0071] At this time, the electrical stimulation control module is configured to execute the working electrode dynamic adjustment control instruction at least once when the current pulse generation unit is operating. In particular, for the interval electrical stimulation mode, the working electrode dynamic adjustment control instruction is executed at least once per working cycle. At this time, the electrode adjustment cycle is configured according to the configured duration of the working cycle so that the working electrode dynamic adjustment control instruction can be fully executed at least once per working cycle.

[0072] When there is only one peripheral root electrode, the working electrode can be adjusted between the main electrode and the root electrode. When there are multiple peripheral root electrodes, the working electrode can be adjusted to one of the peripheral root electrodes by selecting one from the peripheral root electrodes as the working electrode based on a preset root selection rule.

[0073] Preferably, the root electrode selection rule is configured as follows: for each main electrode, after numbering the root electrodes around the main electrode, an initial root electrode list is constructed. In the initial root electrode list, the root electrodes around are sorted in ascending order of numbers; when it is necessary to adjust the working electrode from this main electrode to a root electrode around, the root electrode ranked first in the root electrode list is selected as the current working electrode, and the number of the selected root electrode is moved from the first position to the last position in the root electrode list, and the numbers of the subsequent root electrodes are moved forward in turn, forming an updated root electrode list; in the next adjustment (that is, when it is necessary to adjust the working electrode from this main electrode to a root electrode around), based on the aforementioned updated root electrode list, the root electrode ranked first in the root electrode list is selected as the current working electrode, and the number of the selected root electrode is moved from the first position to the last position in the root electrode list, and the numbers of the subsequent root electrodes are moved forward in turn, forming an updated root electrode list; and so on.

[0074] Figure 5 It is exemplified that the working electrode of the first electrode structure is the main electrode, and when the working electrode of the second electrode structure is adjusted between the main electrode and the root electrodes around, the change in the electrode spacing of the electrical stimulation. At this time, as an example, the initial root electrode list corresponding to the main electrode of the second electrode structure can be [1, 2, 3, 4], and the numbers 1, 2, 3, 4 respectively correspond to the root electrodes around the inner side, outer side, upper side, and lower side of the main electrode. In the initial state, when the main electrode of the second electrode structure is the working electrode, the corresponding electrode spacing is L0; when it is necessary to adjust the working electrode of the second electrode structure, the root electrode corresponding to the number ranked first in the aforementioned list (that is, the number 1) (that is, the root electrode on the inner side of the main electrode) is selected as the working electrode. At this time, the corresponding electrode spacing is L1 < L0, and the updated root electrode list is [2, 3, 4, 1]. Subsequently, when it is necessary to adjust the working electrode of the second electrode structure, the root electrode corresponding to the number ranked first in the aforementioned updated list (that is, the number 2) (that is, the root electrode on the outer side of the main electrode) is selected as the working electrode. At this time, the corresponding electrode spacing is L2 > L0, and the updated root electrode list is [3, 4, 1, 2]. And so on, when the root electrode on the upper side of the main electrode of the second electrode structure is the working electrode, the corresponding electrode spacing is L3 > L0, and the updated root electrode list is [4, 1, 2, 3]; when the root electrode on the lower side of the main electrode of the second electrode structure is the working electrode, the corresponding electrode spacing is L4 > L0, and the updated root electrode list is [1, 2, 3, 4]. In this way, each root electrode around can be selected as the working electrode.

[0075] Through the above solutions provided by the present invention, the dynamic adjustment of the electrode spacing is achieved, thereby dynamically adjusting the current stimulation range. At the same time, the irregularity of the current stimulation is also increased, further prolonging the time for the patient to develop tolerance.

[0076] Preferably, the electrical stimulation control module may be further configured to: differentially set the current pulse intensity when the main electrode and the peripheral root electrodes serve as working electrodes, wherein the current pulse intensity when the main electrode serves as the working electrode may be higher than the current pulse intensity when the peripheral root electrodes serve as working electrodes. If there are multiple peripheral root electrodes surrounding the main electrode, the current pulse intensity when the outer root electrodes serve as working electrodes may be higher than the current pulse intensity when the inner root electrodes serve as working electrodes.

[0077] In another implementation of this embodiment, a patient status identification module may be further included, which is communicatively connected to the electrical stimulation control module.

[0078] Specifically, the patient status recognition module is configured to: collect the patient's physical status data during the electrical stimulation treatment - for example, it can collect the patient's physiological characteristics data, facial expression image data and / or limb movement image data, etc., and determine whether to continue to apply electrical stimulation based on the physical status data - for example, when the collected data exceeds a preset standard value, and / or when it is determined that the patient is unwell after image recognition of facial expression or limb movement image data, it can be determined that electrical stimulation should not be continued at this time. At this time, an instruction to end electrical stimulation is sent to the electrical stimulation control module.

[0079] When the electrical stimulation control module receives the aforementioned end electrical stimulation instruction, it controls the current pulse generating unit to enter a standby state. Optionally, the electronic antiemetic device may further include an alarm module, which emits a sound and / or light alarm.

[0080] Preferably, when the standby state time exceeds a preset time, the current pulse generating unit may enter a shutdown state from the standby state.

[0081] In this embodiment, the electronic antiemetic device may further include other functional modules, such as a power supply module, a power management module, and a display module. The power supply module is used to supply power to the electronic antiemetic device's electrical components. The power management module may include a voltage stabilization circuit, a charging circuit, and a protection circuit. The voltage stabilization circuit is used to achieve voltage stabilization and constant current control; the charging circuit is used for charging management to prevent overcharging; and the protection circuit is used for overcurrent, overvoltage, and short-circuit protection to ensure safe stimulation output. The display module may include indicator lights and a screen to display information such as the antiemetic device's operating status and the progress of electrical stimulation.

[0082] Another embodiment of the present invention further provides a chemotherapy and antiemetic treatment system, which includes at least a body support device and an antiemetic treatment device.

[0083] The body support device is used for allowing the patient to sit or lie down in a preset body posture. Preferably, the body support part is a dynamic chair with an adjustable function, which can be used for the patient to sit or lie down and can be adjusted according to the patient's body shape.

[0084] The antiemetic treatment device includes the electronic antiemetic device of the aforementioned embodiment. When antiemetic treatment is needed, the electrode portion of the electronic antiemetic device electrically stimulates one or more target acupuncture points on one or more body parts of the patient.

[0085] The body parts may specifically include the head, abdomen, arms, legs, neck, back, waist, etc. For any of the aforementioned body parts, after the location of the target acupuncture points with antiemetic effects is located, the electrode portion of the electronic antiemetic device can be used to perform electrical stimulation therapy on one or more target acupuncture points on one or more body parts of the patient.

[0086] The method for locating the target acupuncture point can be manual positioning, that is, manually aligning the electrode part with the target acupuncture point position, or automatic system positioning, that is, the system identifies the target acupuncture point position on the body part and then locates it.

[0087] Preferably, see Figure 6 As shown, the system further comprises an acupoint recognition unit provided corresponding to the body support device, wherein the acupoint recognition unit is used to recognize all acupoint positions on the patient's body and locate target acupoints with antiemetic effect.

[0088] In a specific implementation, the acupoint recognition unit may include an image acquisition structure and an image recognition structure. Preferably, a body part placement location may be provided on the body support device for a specific body part, such as an arm. The image acquisition structure may be provided on the body part placement location. The image acquisition structure scans the body part on the placement location to acquire image data of the body part, and then transmits the body part name (e.g., arm) and the corresponding body part image data to the image recognition structure.

[0089] The image recognition structure is configured to: obtain the size of the body part after recognizing the aforementioned body part image data, and then obtain the name and / or number, function and corresponding position of each acupoint on the body part based on a preset human acupoint information table for each body part. After obtaining the information, combine the obtained information to identify the acupoint on the body part with an antiemetic effect as the target acupoint, and locate the position of the target acupoint.

[0090] For other technical features of the electronic antiemetic device, please refer to the description of the previous embodiment and will not be repeated here.

[0091] In another implementation of this embodiment, the antiemetic treatment device may further include a massage unit for applying massage stimulation to the target acupuncture points.

[0092] See also Figure 7 As shown, the massage unit 200 includes at least a central area 210 and a peripheral area 220 surrounding the central area.

[0093] A first massage structure may be provided in the central area 210 , and an electrode portion 100 of the electronic antiemetic device may be provided on the massage head of the first massage structure to electrically stimulate the target acupuncture point.

[0094] A second massage structure may be provided in the peripheral area 220 for surrounding the target acupuncture point and massaging and stimulating the target acupuncture point from the outside to the inside or from the inside to the outside.

[0095] In a preferred embodiment, the massage head of the first massage structure is a multi-layer nested structure, see Figure 8 As shown, it may include an inner layer 211, a first rotating layer 212 sleeved outside the inner layer 211, and a second rotating layer 213 sleeved outside the first rotating layer 212. The electrode part 100 is arranged on the surface of the inner layer 211, and the inner layer 211 can be telescopically adjusted relative to the first rotating layer 212. The first rotating layer 212 can be telescopically adjusted relative to the second rotating layer 213.

[0096] The antiemetic treatment device is configured to: collect size information of the patient's body parts, determine the patient type based on the size information of the body parts, and adjust the telescopic state of each layer of the massage head according to the patient type to adjust the contact area between the massage head and the patient's skin.

[0097] Specifically, as a preference, the patient type may include a child type and a general user type. In this case, the antiemetic treatment device is configured as follows: when the patient is determined to be a child type, the inner layer and the first rotating layer are extended and contact the patient's skin, electrical stimulation is performed through the inner layer, and skin massage is performed through the rotation of the first rotating layer. Figure 8 When the patient is determined to be a normal user type, the inner layer and the first rotating layer are retracted, electrical stimulation is performed through the inner layer, and skin massage is performed by rotating the first rotating layer and the second rotating layer. Figure 8 As shown in the left picture.

[0098] Preferably, in the initial state, the inner layer 211 and the first rotating layer 212 of the massage head of the first massage structure are in the retracted state. At this time, the surfaces of the inner layer 211, the first rotating layer 212 and the second rotating layer 213 are flush. When determining the type of child, the inner layer and the first rotating layer are controlled to be extended to contact the patient's skin.

[0099] In this embodiment, the massage stimulation is preferably a contraction and expansion massage. In this case, the second massage structure includes a massage head for achieving the contraction and expansion functions, and the massage head is provided with a liquid outlet. In this way, the second massage structure massages the area around the target acupuncture point, which can effectively stretch the area around the target acupuncture point.

[0100] Correspondingly, it also includes a liquid delivery module, which includes a liquid delivery path corresponding to the massage head, and the output end of the liquid delivery path is connected to the liquid derivation hole on the massage head.

[0101] The liquid delivery module is configured to: upon receiving a liquid delivery instruction sent by the antiemetic treatment device, control the liquid delivery path to be connected to the liquid outlet hole of the corresponding massage head according to the massage head information in the liquid delivery instruction, and then deliver liquid to the corresponding massage head.

[0102] The liquid may be, for example, a massage lubricant, essential oil or other liquid. Thus, the liquid can assist in lubrication or stimulate the meridians during massage.

[0103] Preferably, the liquid discharge instruction may also include a single liquid discharge volume and liquid discharge cycle information. In this case, the liquid delivery module is configured to: measure the liquid delivery volume when delivering liquid to the corresponding massage head; when the delivered liquid volume reaches the aforementioned single liquid discharge volume, stop liquid delivery and wait for the next liquid discharge cycle; when the next liquid discharge cycle arrives, control the liquid discharge again.

[0104] As a further preference, the central area may be provided with a plurality of first massage structures, and the plurality of first massage structures are located at different positions of the central area to form a plurality of massage sub-areas, and a drive motor is provided corresponding to each massage sub-area.

[0105] The antiemetic treatment device is configured to: based on a preset time period T1, within one of the time periods T1, control the start of the drive motors of each massage sub-area according to a preset central stimulation strategy to drive the first massage structure action of each massage sub-area to stimulate different positions of the target acupuncture points; after the massage action of one time period T1 is completed, determine whether the massage time length of the target acupuncture point reaches a preset massage standard time; if it is determined that the massage standard time has not been reached, enter the next time period T1 and repeat the aforementioned stimulation strategy; if it is determined that the massage standard time has been reached, end the central area massage.

[0106] Specifically, the central area can be divided into a central sub-area and multiple corner sub-areas. The central stimulation strategy is configured to: within a time period T1, configure different stimulation parameters for the massage heads in the central sub-area and the corner sub-areas. The stimulation intensity in the central sub-area can be higher than that in the corner sub-areas.

[0107] As a further preferred embodiment, the peripheral area may be provided with a plurality of second massage structures, wherein the plurality of second massage structures form at least two massage rings in the peripheral area. Figure 9 As shown, an example is given of forming a first massage ring belt sub-area 2201 and a second massage ring belt sub-area 2201, and a second massage structure 221 is set at different positions of each massage ring belt to form a massage ring belt sub-area, and a driving motor is set corresponding to each massage ring belt sub-area.

[0108] At this time, the antiemetic treatment device is configured as follows: based on a preset time period T2, within one of the time periods T2, the drive motors of each massage ring belt sub-area are controlled to start according to a preset peripheral stimulation strategy to drive the second massage structure action of each massage ring belt sub-area to stimulate the periphery of the target acupuncture point; after the massage action of one time period T2 is completed, it is determined whether the length of the peripheral massage time reaches the preset massage standard time; when it is determined that the massage standard time has not been reached, the next time period T2 is entered, and the aforementioned peripheral stimulation strategy is repeatedly executed; when it is determined that the massage standard time has been reached, the peripheral area massage is ended.

[0109] Preferably, the peripheral stimulation strategy is configured to configure different stimulation parameters for the massage heads in different massage rings within the time period T2. Specifically, for example, the massage intensity of the massage heads in the inner massage ring is higher than that of the massage heads in the outer massage ring, thereby producing differentiated massage effects.

[0110] Through the above technical solution, electrical stimulation of the central area is combined with massage stimulation of the peripheral area. While applying electrical stimulation to the acupoints, massage stimulation is applied by the massage unit to enhance the stimulation effect, further alleviating or treating vomiting symptoms in patients undergoing chemotherapy for cancer. Specifically, the central area and the peripheral area are divided into sub-areas. As needed, the acupoints and different locations around the acupoints can be stimulated. Optionally, temperature differences can be set for different areas, and the stimulation of temperature differences can be used to enhance the stimulation effect.

[0111] In the above description, the disclosure of the present invention is not intended to limit itself to these aspects. Rather, within the scope of the intended protection of the present disclosure, the components can be selectively and operationally combined in any number. In addition, terms such as "including", "encompassing" and "having" should be interpreted as inclusive or open by default, rather than exclusive or closed, unless they are explicitly defined to the contrary. All technical, scientific or other terms have the meaning understood by those skilled in the art unless they are defined to the contrary. Common terms found in dictionaries should not be interpreted too idealistically or too impractically in the context of relevant technical documents, unless the present disclosure explicitly defines them as such. Any changes and modifications made by a person of ordinary skill in the field of the present invention based on the above disclosure are within the scope of protection of the claims.

Claims

1. An electronic antiemetic device based on electrical stimulation, characterized in that include: an electrode portion, for contacting an acupuncture point having an antiemetic effect on a body part of a patient and applying non-invasive electrical stimulation; a current pulse generating unit, electrically connected to the electrode unit, for generating a controllable current pulse and transmitting the current pulse to the electrode unit; an electrical stimulation control module electrically connected to the current pulse generating unit and configured to control the operation of the current pulse generating unit; wherein the electrical stimulation control module is configured to: receive an electrical stimulation instruction, and according to the interval time and current pulse parameters configured in the electrical stimulation instruction, control the current pulse generating unit to intermittently enter the working state according to the interval time, and generate current pulses according to the aforementioned current pulse parameters; The electrode portion includes two electrode structures for contacting the patient's skin, the first electrode structure is a positive electrode, and the second electrode structure is a negative electrode; The electrode structure is a plant root-mimicking structure, comprising a central main electrode and peripheral root electrodes located on the periphery of the main electrode; electrode drive motors are provided corresponding to the main electrode and the peripheral root electrodes for driving the electrode heads of the corresponding electrodes to extend and retract, and the electrode drive motors are connected to and controlled by the electrical stimulation control module; The electrical stimulation control module is configured to: when the working time of the current pulse generating unit arrives, control the electrode driving motor so that one electrode head of the first electrode structure and the second electrode structure contacts the skin as a working electrode, forming the positive electrode and negative electrode of the current loop respectively; and, during the application of electrical stimulation, control the electrode driving motor to drive the electrode heads on the first electrode structure and the second electrode structure to contact or move away from the skin to adjust the working electrodes, and adjust the electrode spacing for applying electrical stimulation by adjusting the working electrodes.

2. The electronic antiemetic device according to claim 1, characterized in that: It includes a user interaction unit for collecting the electrical stimulation mode and current pulse parameters selected by the user; The electrical stimulation mode includes a continuous electrical stimulation mode and an interval electrical stimulation mode, each corresponding to a different electrical stimulation instruction; The current pulse parameters include current pulse output duration and current pulse output intensity information; For the interval electrical stimulation mode, the current pulse output duration of the current pulse parameter includes the total working duration, the number of working cycles and the working duration of each working cycle.

3. The electronic antiemetic device according to claim 1, characterized in that: A working electrode dynamic adjustment control instruction is preset, and the working electrode dynamic adjustment control instruction is configured to: in an initial state, the main electrodes of the first electrode structure and the second electrode structure are used as working electrodes, and when a preset electrode adjustment cycle arrives, the working electrode of the first electrode structure is adjusted to one of the peripheral root electrodes, and the working electrode of the second electrode structure remains the main electrode unchanged, waiting for the next electrode adjustment cycle to arrive; When the next electrode adjustment cycle arrives, the working electrode of the first electrode structure is restored to the main electrode, and the working electrode of the second electrode structure is adjusted to one of the peripheral root electrodes. When the electrode adjustment cycle ends, the working electrode adjustment is terminated and the state is restored to the initial state. The electrical stimulation control module is configured to: execute the working electrode dynamic adjustment control instruction at least once when the current pulse generating unit is working; wherein, for the interval electrical stimulation mode, the working electrode dynamic adjustment control instruction is executed at least once per working cycle.

4. The electronic antiemetic device according to claim 3, characterized in that: The electrical stimulation control module is further configured to: set different current pulse intensities for the main electrode and the peripheral root electrodes as working electrodes, so that the current pulse intensity when the main electrode is used as the working electrode is higher than the current pulse intensity when the peripheral root electrodes are used as working electrodes; as well as, When there are multiple peripheral root electrodes around the main electrode, the current pulse intensity of the outer root electrodes as working electrodes is higher than the current pulse intensity of the inner root electrodes as working electrodes.

5. The electronic antiemetic device according to claim 1, characterized in that: The device further includes a patient status recognition module, which is in communication with the electrical stimulation control module and is configured to: collect physical status data of the patient during the electrical stimulation treatment, determine whether to continue to apply electrical stimulation based on the physical status data, and send an instruction to the electrical stimulation control module to end the electrical stimulation when it is determined that electrical stimulation is not to be applied; When receiving the aforementioned instruction to end electrical stimulation, the electrical stimulation control module controls the current pulse generating unit to enter a standby state.

6. A chemotherapy and antiemetic treatment system, characterized by: Body support device, used for patients to sit or lie in a preset body posture; An antiemetic treatment device comprises the electronic antiemetic device according to any one of claims 1 to 5, wherein the electrode portion of the electronic antiemetic device is used to perform electrical stimulation treatment on one or more target acupuncture points on one or more body parts of a patient.

7. The chemotherapy and antiemetic treatment system according to claim 6, characterized in that: The antiemetic treatment device further comprises a massage unit, wherein the massage unit comprises at least a central area and a peripheral area surrounding the central area; The central area is provided with a first massage structure, and the massage head of the first massage structure is provided with an electrode portion of the electronic antiemetic device for electrically stimulating the target acupuncture point; The peripheral area is provided with a second massage structure for surrounding the target acupuncture point position and massaging and stimulating the target acupuncture point from the outside to the inside or from the inside to the outside.

8. The chemotherapy and antiemetic treatment system according to claim 7, characterized in that: The massage head of the first massage structure is a multi-layer nested structure, including an inner layer, a first rotating layer sleeved outside the inner layer, and a second rotating layer sleeved outside the first rotating layer. The electrode portion is provided on the surface of the inner layer. The inner layer is capable of expansion and contraction adjustment relative to the first rotating layer, and the first rotating layer is capable of expansion and contraction adjustment relative to the second rotating layer. The antiemetic treatment device is configured to: collect size information of the patient's body parts, determine the patient type based on the size information of the body parts, and then adjust the telescopic state of each layer of the massage head according to the patient type to adjust the contact area between the massage head and the patient's skin; wherein, when the patient is a child type, the inner layer and the first rotating layer are in an extended state and contact the patient's skin, electrical stimulation is performed through the inner layer, and skin massage is performed by rotating the first rotating layer; when the patient is an ordinary user type, the inner layer and the first rotating layer are in a retracted state, electrical stimulation is performed through the inner layer, and skin massage is performed by rotating the first rotating layer and the second rotating layer.

9. The chemotherapy and antiemetic treatment system according to claim 8, characterized in that: The massage stimulation is a contraction and expansion massage, and the second massage structure includes a massage head for achieving the contraction and expansion functions, and the massage head is provided with a liquid outlet hole; It also includes a liquid delivery module, which includes a liquid delivery path set corresponding to the massage head, and the output end of the liquid delivery path is connected to the liquid outlet hole on the massage head: the liquid delivery module is configured to: when receiving a liquid discharge instruction sent by the anti-emetic treatment device, control the liquid delivery path to be connected to the liquid outlet hole of the corresponding massage head according to the massage head information in the liquid discharge instruction, and then deliver liquid to the corresponding massage head.

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