A microfluidic chip-based simulation device and method for mass transfer of bubbles in a fluid

Abstract

The application discloses a kind of fluid in bubble mass transfer simulation device and method based on microfluidic chip.Microfluidic chip is installed on microfluidic chip fixed module, the inlet and outlet of microfluidic chip are communicated with gas-liquid mixed injection module and waste liquid collection tank respectively, microscope is used to observe the bubble preparation process in fluid in microfluidic chip, and bubble mass transfer experiment process uses industrial camera to carry out real-time imaging observation;Method includes processing microfluidic chip;Gas and liquid are injected into microfluidic chip using gas-liquid mixed injection module;Microfluidic chip carrying bubble is fixed on microfluidic chip fixed module;The process that bubble in microfluidic chip is redistributed and evolved under the influence of gravity instability is observed, and the law that bubble matures mass transfer under microgravity or supergravity condition is obtained.The application can restore the residual capture state of carbon dioxide bubble in rock pore, and has important significance for evaluating the long-term safety and stability of carbon dioxide geological storage project.

Description

TECHNICAL FIELD

[0001] The application belongs to the field of porous medium fluid mass transfer model experiment, and particularly relates to a fluid internal bubble mass transfer simulation device and method based on a microfluidic chip. BACKGROUND

[0002] In recent years, with the construction of major projects such as underground carbon dioxide geological storage, underground oil and gas exploitation, underground hydrogen storage and seabed hydrate exploitation, the long-term redistribution process of bubbles in pores under the influence of gravity has attracted widespread attention. Taking carbon dioxide geological storage as an example, carbon dioxide bubbles in a residual capture state existing in the pore structure of a reservoir will be mass transferred upward in the form of thermal diffusion under the influence of gravity, which poses a threat to the long-term safety and stability of the carbon dioxide geological storage project, and therefore it is of great significance to evaluate the long-term evolution process of bubbles in a porous medium system.

[0003] However, in simulation experiments, it is difficult to study the process by using rock samples because the bubble migration process in pores cannot be directly observed. In addition, model preparation at the beginning of the experiment and the sealing property during the experiment are also important problems. Therefore, how to simply and conveniently prepare a model for bubble redistribution evolution experiment in a pore structure has become a technical problem, and currently the research and analysis of this process are mostly limited to the theoretical level, and a set of experimental devices and methods are urgently needed for verification. SUMMARY

[0004] In order to solve the problems in the background art, the purpose of the present application is to provide a fluid internal bubble mass transfer simulation device and method based on a microfluidic chip. The model is prepared under a microscope, the bubbles are sealed in a double-depth pore microfluidic chip by a gas-liquid mixed injection method, the bubbles are sealed in the pore structure by using a microfluidic chip fixing module, the bubble redistribution evolution experiment under the influence of unstable gravity is carried out through the above preparation process, and the laws of bubble maturation and mass transfer under the influence of gravity are analyzed, which is of great significance to the evaluation of the long-term safety and stability of the carbon dioxide geological storage project.

[0005] The technical scheme adopted by the present application is as follows:

[0006] I. A fluid internal bubble mass transfer simulation device based on a microfluidic chip:

[0007] The device comprises a gas-liquid mixed injection module, a microfluidic chip, a microfluidic chip fixing module, a waste liquid collection tank, a microscope and a control machine. The microfluidic chip is installed on the microfluidic chip fixing module, the inlet and outlet of the microfluidic chip are respectively communicated with the outlet of the gas-liquid mixed injection module and the inlet of the waste liquid collection tank, the gas-liquid mixed injection module and the microscope are connected with the control machine, and the microscope is used for real-time imaging of the bubble preparation process in the fluid in the microfluidic chip.

[0008] The gas-liquid mixing module includes a carbon dioxide collection bottle, a check valve, a drain tube, a pressure controller, an organic solvent collection tube, and a guide tube. The outlets of the carbon dioxide collection bottle and the organic solvent collection tube are both connected to one end of the pressure controller through the drain tube. A check valve is installed on the drain tube from the carbon dioxide collection bottle to the pressure controller. The other end of the pressure controller is connected to the injection port of the microfluidic chip through the guide tube. A check valve is installed on the guide tube. The carbon dioxide collection bottle is used to provide carbon dioxide, and the organic solvent collection tube is used to provide fluid. The pressure controller is connected to the controller.

[0009] The pore depth of the microfluidic chip is greater than the throat depth. The pore depth of the microfluidic chip is 30μm to 35μm, and the throat depth of the microfluidic chip is 10μm to 12μm.

[0010] The microfluidic chip fixing module includes an aluminum fixing clamp, a fixing groove, and a sealing clamp. The microfluidic chip is fixedly installed on the fixing groove of the aluminum fixing clamp. The sealing clamp is installed on the side of the aluminum fixing clamp by bolts, and there is a gap between the aluminum fixing clamp and the sealing clamp. The sealing clamp is used to seal and fix the guide tube. One end of the guide tube is connected to the injection port of the microfluidic chip, and the other end of the guide tube passes through the gap between the aluminum fixing clamp and the sealing clamp and is connected to the pressure controller.

[0011] The microfluidic chip includes an injection port, an outlet port, and a porous media region. The injection port and the outlet port are respectively located on both sides of the porous media region. The porous media region is mainly formed by a number of dual-depth pore units arranged in a rectangular interval array. The injection port and the outlet port are connected to the porous media region through a number of diversion pipes evenly distributed along the length of the microfluidic chip. The outlet port of the microfluidic chip is connected to a waste liquid collection tank.

[0012] The microfluidic chip is fabricated using an etching process.

[0013] II. A method for simulating mass transfer of air bubbles in fluids based on a microfluidic chip, comprising the following steps:

[0014] Step S1: First, microfluidic chips are fabricated using an etching process, and an organic solvent for staining is prepared.

[0015] Step S2: Next, gas and liquid are injected into the microfluidic chip using the gas-liquid mixing module to form bubbles inside the microfluidic chip;

[0016] Step S3: Then, fix the microfluidic chip onto the microfluidic chip fixing module;

[0017] Step S4: Observe the redistribution evolution of bubbles in the microfluidic chip under the influence of gravitational instability under microgravity or hypergravity conditions, and obtain the law of bubble maturation and mass transfer under microgravity or hypergravity conditions.

[0018] The specific steps of step S2 are as follows:

[0019] First, the fabricated microfluidic chip is placed on the microscope stage. The stained organic solvent is injected into the organic solvent collection tube. The pressure controller in the gas-liquid mixing module is used to input gas and liquid with stable pressure into the microfluidic chip through the carbon dioxide collection bottle and the organic solvent collection tube. The two liquids and one gas mix in the pipeline to form bubbles, which are then injected into the microfluidic chip through the split pipeline. The presence of bubbles in the microfluidic chip is monitored in real time using a microscope. The fabrication of the microfluidic chip is completed when the bubbles exist in the pores of the microfluidic chip in the form of residual trapping.

[0020] The specific steps of step S3 are as follows:

[0021] The prepared microfluidic chip is removed from the microscope stage and installed on the microfluidic chip fixing module. The guide tube connected to the injection port of the microfluidic chip is sealed and clamped by the sealing clamp to make the inside of the microfluidic chip a closed environment. After a preset time, the guide tube between the sealing clamp and the pressure controller is cut off.

[0022] Under microgravity conditions, the specific steps of step S4 are as follows:

[0023] Adjust the microfluidic chip to a preset tilt angle and observe the mass transfer law of bubbles in the microfluidic chip under microgravity conditions, thereby obtaining the law of mass transfer of bubble maturation under the influence of microgravity under real working conditions;

[0024] Under hypergravity conditions, the specific steps of step S4 are as follows:

[0025] The microfluidic chip mounting module with the microfluidic chip installed is placed on the basket of the centrifuge. The centrifuge is started. After the centrifugal acceleration reaches N times the gravitational acceleration and stabilizes, the mass transfer law of the bubbles in the microfluidic chip under Ng hypergravity conditions is observed, so as to obtain the law of mass transfer of bubble maturation under hypergravity under real working conditions.

[0026] This invention utilizes a microscope to prepare a model and encapsulates bubbles in a microfluidic chip with dual-depth pores via gas-liquid mixing. A microfluidic chip fixing module further secures the bubbles within the pore structure. Experiments are conducted to analyze the redistribution and evolution of bubbles under the influence of gravitational instability, analyzing the maturation and mass transfer mechanisms of bubbles under gravity. This invention can modify the pore distribution within a microfluidic chip to prepare and encapsulate bubbles or multiphase bioreaction flows, providing a guarantee for subsequent mass transfer / reaction experiments and holding significant implications for assessing the long-term safety and stability of carbon dioxide geological sequestration projects.

[0027] This invention allows for the stable mixing and injection of gas and liquid into a microfluidic chip under a microscope using a pressure controller, creating bubbles within the chip's pores. After sealing, the multiphase bubble maturation process can be experimentally monitored under specific conditions. Alternatively, fluid can be injected into the microfluidic chip under a microscope using the same pressure controller to conduct single-phase displacement experiments, or bioreactive fluid can be injected to conduct multiphase bioreactive flow experiments. The device enables the preparation and sealing of single-phase and multiphase fluids within the pore structure of a microfluidic chip, providing a foundation for subsequent observational experiments. This significantly aids in assessing the long-term safety and stability of carbon dioxide geological sequestration projects.

[0028] The beneficial effects of this invention are:

[0029] 1. The present invention adopts a dual-depth pore unit structure design, which can restore the residual trapped state of bubbles in rock pores.

[0030] 2. This invention can change the pore distribution in a microfluidic chip, inject different fluids, and conduct different single / multiphase fluid experiments.

[0031] 3. This invention encloses the microfluidic chip, providing a stable guarantee for bubble experiments.

[0032] 4. This invention is of great help in the subsequent observation of the long-term evolution of bubbles in porous media, and is of great significance for assessing the long-term safety and stability of carbon dioxide geological storage projects. Attached Figure Description

[0033] Figure 1 This is a diagram of the bubble model preparation device of the present invention;

[0034] Figure 2 This is a schematic diagram of the microfluidic chip structure of the present invention;

[0035] Figure 3 This is a schematic diagram of a microfluidic chip enclosed and fixed module.

[0036] In the diagram: 1-Carbon dioxide collection bottle; 2-Check valve; 3-Drainage tube; 4-Pressure controller; 5-Organic solvent collection tube; 6-Microfluidic chip; 7-Waste liquid collection tank; 8-Microscope; 9-Gas-liquid mixing module; 10-Controller; 11-Diverter line; 12-Injection port; 13-Outlet port; 14-Pore; 15-Pore throat; 16-Dual-depth pore unit; 17-Microfluidic chip fixing module; 18-Bolt; 19-Drainage tube; 20-Fixing groove; 21-Sealing clamp. Detailed Implementation

[0037] The present invention will be described in detail below with reference to specific implementation examples. These examples will help those skilled in the art to further understand the present invention, but do not limit the present invention in any way.

[0038] like Figure 1 As shown, the device includes a gas-liquid mixing module 9, a microfluidic chip 6, a microfluidic chip fixing module 17, a waste liquid collection tank 7, a microscope 8, and a controller 10. The microfluidic chip 6 is mounted on the microfluidic chip fixing module 17. The inlet and outlet of the microfluidic chip 6 are connected to the outlet of the gas-liquid mixing module 9 and the inlet of the waste liquid collection tank 7, respectively. Both the gas-liquid mixing module 9 and the microscope 8 are connected to the controller 10. The microscope 8 is used to perform real-time imaging of the bubble preparation process in the fluid of the microfluidic chip 6.

[0039] In the bubble mass transfer simulation experiment under hypergravity conditions, the simulation device of this invention is placed on the basket of a centrifuge. The gas-liquid mixing module 9 is used to stably inject gas and liquid into the microfluidic chip 6, causing bubbles to form within the microfluidic chip 6. The microfluidic chip 6 is provided with a dual-depth pore unit 16, which allows the bubbles to be independently sealed within the pore structure of the microfluidic chip 6 in a residual closed form. The microfluidic chip fixing module 17 is used to clamp and seal the guide tube 19 of the gas-liquid mixing module 9 after the bubbles are sealed within the pore structure, ensuring the bubbles exist in a closed environment. The microfluidic chip 6 is placed in the fixing groove 20 of the microfluidic chip fixing module 17. The waste liquid collection tank 7 is used to collect excess liquid flowing out during the bubble preparation process. The microscope 8 is used for real-time observation of the bubble input and existence state during the bubble preparation process. The controller 10 is used to regulate the input pressure of the pressure controller 4 and simultaneously receive real-time images transmitted from the microscope 8.

[0040] The gas-liquid mixing module 9 includes a carbon dioxide collection bottle 1, a check valve 2, a drainage tube 3, a pressure controller 4, an organic solvent collection tube 5, and a guide tube 19. The outlets of the carbon dioxide collection bottle 1 and the organic solvent collection tube 5 are connected to one end of the pressure controller 4 through the drainage tube 3. A check valve 2 is provided on the drainage tube 3 from the carbon dioxide collection bottle 1 to the pressure controller 4. The other end of the pressure controller 4 is connected to the injection port 12 of the microfluidic chip 6 through the guide tube 19. The microfluidic chip (6) is input into the form of two liquids and one gas by inputting a stable pressure. A check valve 2 is provided on the guide tube 19. The carbon dioxide collection bottle 1 is used to provide carbon dioxide, the organic solvent collection tube 5 is used to provide fluid, and the pressure controller 4 is connected to the controller 10.

[0041] The pressure controller 4 is used to input gas and liquid at a stable pressure into the inlet of the microfluidic chip 6 in the form of two liquids and one gas. One gas from the carbon dioxide collection bottle 1 is input into the inlet of the microfluidic chip 6 at a stable pressure after passing through the pressure controller 4. The two liquids from the organic solvent collection tube 5 are input into the inlet of the microfluidic chip 6 at a stable pressure after passing through the pressure controller 4. The outlet of the three pipelines, one gas and two liquids, is a narrow channel. The gas and two liquids are mixed at the outlet of the three pipelines and then input into the microfluidic chip 6, which aims to continuously input bubbles into the microfluidic chip 6.

[0042] like Figure 2 As shown, the microfluidic chip 6 adopts a dual-depth pore structure design. The depth of pore 14 is greater than the depth of pore throat 15. The depth of pore 14 in the microfluidic chip 6 is 30μm to 35μm, and the depth of pore throat 15 in the microfluidic chip 6 is 10μm to 12μm.

[0043] The microfluidic chip 6 of the present invention adopts a dual-depth pore unit 16, which is composed of pores 14 and pore throats 15 with different depths. Compared with the setting of pores and pore throats with the same depth in traditional microfluidic chips, the pore 14 depth of the microfluidic chip 6 of the present invention is much greater than the pore throat 15 depth. This near three-dimensional pore pattern can make the bubbles more stably and independently retained in the pore structure of the microfluidic chip.

[0044] like Figure 3 As shown, the microfluidic chip fixing module 17 includes an aluminum fixing fixture, a fixing groove 20, and a sealing clamp 21. The microfluidic chip 6 is fixedly installed on the fixing groove 20 of the aluminum fixing fixture. The sealing clamp 21 is installed on the side of the aluminum fixing fixture by bolts 18, and there is a gap between the aluminum fixing fixture and the sealing clamp 21. The sealing clamp 21 is used to seal and fix the guide tube 19. One end of the guide tube 19 is connected to the injection port 12 of the microfluidic chip 6, and the other end of the guide tube 19 passes through the gap between the aluminum fixing fixture and the sealing clamp 21 and is connected to the pressure controller 4.

[0045] In practice, after the bubbles are independently sealed within the microfluidic chip 6 in the form of residual capture, the aluminum fixing clamp fixes the microfluidic chip 6. The injection guide tube 19 passes between the aluminum fixing clamp and the sealing clamp 21. The sealing clamp 21 is tightened with bolts 18 to seal the guide tube 19, so that the microfluidic chip 6 is in a closed environment. After stabilizing for a period of time, the guide tube 19 between the sealing clamp 21 and the pressure controller 4 is cut off.

[0046] The microfluidic chip 6 includes an injection port 12, an outlet port 13, and a porous medium region. The injection port 12 and the outlet port 13 are respectively located on both sides of the porous medium region. The porous medium region is mainly formed by a number of dual-depth pore units 16 arranged in a rectangular interval array. The injection port 12 and the outlet port 13 are both connected to the porous medium region through a number of shunt pipes 11 evenly distributed along the length direction of the microfluidic chip 6. The outlet port 13 of the microfluidic chip 6 is connected to the waste liquid collection tank 7.

[0047] Eight shunt channels 11 are provided on each side of the porous medium region to better retain bubbles in each pore of the microfluidic chip 6, that is, the bubble saturation of the microfluidic chip 6 is consistent from top to bottom. The sixteen shunt channels 11, injection port 12, outlet port 13 and dual-depth pore unit 16 of the microfluidic chip 6 are all processed by etching process.

[0048] The microfluidic chip 6 is fabricated using an etching process.

[0049] The embodiments of the present invention include the following steps:

[0050] Step S1: First, a microfluidic chip 6 with dual-depth pore units 16 is fabricated using an etching process, and a dyeing organic solvent is prepared: an organic solvent with a density close to that of salt water is prepared, and the organic solvent is dyed with dye to facilitate the observation of the presence of bubbles in the microfluidic chip 6.

[0051] Step S2: Next, gas and liquid are injected into the microfluidic chip 6 using the gas-liquid mixing module 9;

[0052] Step S3: Then, fix the microfluidic chip 6 onto the microfluidic chip fixing module 17;

[0053] Step S4: Observe the redistribution evolution of bubbles in the microfluidic chip 6 under microgravity or hypergravity conditions, and obtain the law of bubble maturation and mass transfer under microgravity or hypergravity conditions.

[0054] Step S2 is as follows:

[0055] First, the fabricated microfluidic chip 6 is placed on the stage of the microscope 8. The carbon dioxide collection bottle 1 and the organic solvent collection tube 5 are connected to the input end of the pressure controller 4 through the drainage tube 3, respectively. The output end of the pressure controller 4 is connected to the injection port 12 of the microfluidic chip 6 through the guide tube 19. The outlet port 13 of the microfluidic chip 6 is connected to the waste liquid collection tank 7. The dyed organic solvent is injected into the organic solvent collection tube 5. The pressure controller 4 in the gas-liquid mixing module 9 is used to input gas and liquid with stable gas pressure into the microfluidic chip 6 through the carbon dioxide collection bottle 1 and the organic solvent collection tube 5, respectively. The two liquids and one gas mix in the pipeline to form bubbles, which are then injected into the microfluidic chip 6 through the split pipeline 11. The microscope 8 is used to monitor the existence of bubbles in the microfluidic chip 6 in real time. The controller 10 receives the image information transmitted back by the microscope 8. When the bubbles are close to saturation and exist in the pores of the microfluidic chip 6 in the form of residual capture, the fabrication of the bubble-carrying microfluidic chip 6 is completed.

[0056] Step S3 is as follows:

[0057] The prepared microfluidic chip 6 carrying air bubbles is removed from the stage of the microscope 8 and placed into the aluminum fixture of the microfluidic chip fixing module 17. In order to minimize the disturbance to the air bubbles inside the chip, the guide tube 19 connected to the injection port 12 of the microfluidic chip 6 is sealed and clamped by the sealing clamp 21 to form a flow stop, so that the inside of the microfluidic chip 6 is in a closed environment. After stabilizing for a period of time, the guide tube 19 between the sealing clamp 21 and the pressure controller 4 is cut off.

[0058] Under microgravity conditions, the specific steps of step S4 are as follows:

[0059] By using the microfluidic chip fixing module 17 to adjust the microfluidic chip 6 to a preset tilt angle, the mass transfer law of bubbles in the microfluidic chip 6 under microgravity conditions is observed, thereby obtaining the law of mass transfer of bubble maturation under the influence of microgravity under real working conditions.

[0060] Specifically, the acceleration under microgravity conditions is less than the acceleration g under normal gravity, which can be achieved by tilting the microfluidic chip 6 at a certain angle.

[0061] Under hypergravity conditions, the specific steps of step S4 are as follows:

[0062] The microfluidic chip fixing module 17, which is equipped with the microfluidic chip 6, is placed on the basket of the centrifuge. The centrifuge is started. After the centrifugal acceleration reaches N times the gravitational acceleration and stabilizes, the mass transfer law of the bubbles in the microfluidic chip 6 under the Ng hypergravity condition is observed, so as to obtain the law of mass transfer of bubble maturation under the influence of hypergravity under real working conditions.

[0063] This invention utilizes a microscope (8) to prepare a model. Bubbles are encapsulated within a microfluidic chip (6) of a dual-depth pore unit (16) using a gas-liquid mixing method. The microfluidic chip fixing module (17) further secures the bubbles within the pore structure. Experiments are conducted to analyze the redistribution and evolution of bubbles under the influence of gravitational instability, analyzing the maturation and mass transfer mechanisms of bubbles under gravity. This invention can alter the pore distribution within the microfluidic chip to facilitate single-phase displacement or multiphase bubble maturation, and the preparation and encapsulation of multiphase bioreactive flows. This provides a guarantee for subsequent mass transfer / reaction experiments and is of great significance for assessing the long-term safety and stability of carbon dioxide geological storage projects.

[0064] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A fluid bubble mass transfer simulation device based on a microfluidic chip, characterized in that: The system includes a gas-liquid mixing module (9), a microfluidic chip (6), a microfluidic chip fixing module (17), a waste liquid collection tank (7), a microscope (8), and a controller (10). The microfluidic chip (6) is installed on the microfluidic chip fixing module (17). The inlet and outlet of the microfluidic chip (6) are connected to the outlet of the gas-liquid mixing module (9) and the inlet of the waste liquid collection tank (7), respectively. The gas-liquid mixing module (9) and the microscope (8) are both connected to the controller (10). The microscope (8) is used to perform real-time imaging of the bubble preparation process in the fluid of the microfluidic chip (6). The gas-liquid mixing module (9) includes a carbon dioxide collection bottle (1), a check valve (2), a drainage tube (3), a pressure controller (4), an organic solvent collection tube (5), and a guide tube (19). The outlets of the carbon dioxide collection bottle (1) and the organic solvent collection tube (5) are connected to one end of the pressure controller (4) through the drainage tube (3). A check valve (2) is provided on the drainage tube (3) from the carbon dioxide collection bottle (1) to the pressure controller (4). The other end of the pressure controller (4) is connected to the injection port (12) of the microfluidic chip (6) through the guide tube (19). A check valve (2) is provided on the guide tube (19). The carbon dioxide collection bottle (1) is used to provide carbon dioxide, the organic solvent collection tube (5) is used to provide fluid, and the pressure controller (4) is connected to the controller (10). The microfluidic chip (6) adopts a dual-depth pore structure design. The pore (14) depth of the microfluidic chip (6) is greater than the pore throat (15) depth. The pore (14) depth of the microfluidic chip (6) is 30μm to 35μm, and the pore throat (15) depth of the microfluidic chip (6) is 10μm to 12μm. The pressure controller (4) is used to input gas and liquid at a stable pressure into the inlet of the microfluidic chip (6) in the form of two liquids and one gas. One gas from the carbon dioxide collection bottle (1) is input into the inlet of the microfluidic chip (6) at a stable pressure after passing through the pressure controller (4). The two liquids from the organic solvent collection tube (5) are input into the inlet of the microfluidic chip (6) at a stable pressure after passing through the pressure controller (4). The outlet of the three pipelines, one gas and two liquids, is a narrow channel. One gas and two liquids are mixed at the outlet of the three pipelines and then input into the microfluidic chip (6), continuously inputting bubbles into the microfluidic chip (6).

2. The fluid bubble mass transfer simulation device based on a microfluidic chip according to claim 1, characterized in that: The microfluidic chip fixing module (17) includes an aluminum fixing fixture, a fixing groove (20), and a sealing clamp (21). The microfluidic chip (6) is fixedly installed on the fixing groove (20) of the aluminum fixing fixture. The sealing clamp (21) is installed on the side of the aluminum fixing fixture by bolts (18), and there is a gap between the aluminum fixing fixture and the sealing clamp (21). The sealing clamp (21) is used to seal and fix the guide tube (19). One end of the guide tube (19) is connected to the injection port (12) of the microfluidic chip (6), and the other end of the guide tube (19) passes through the gap between the aluminum fixing fixture and the sealing clamp (21) and is connected to the pressure controller (4).

3. The fluid bubble mass transfer simulation device based on a microfluidic chip according to claim 1, characterized in that: The microfluidic chip (6) includes an injection port (12), an outlet port (13), and a porous medium region. The injection port (12) and the outlet port (13) are respectively located on both sides of the porous medium region. The porous medium region is mainly formed by a number of double-depth pore units (16) arranged in a rectangular interval array. The injection port (12) and the outlet port (13) are connected to the porous medium region through a number of diversion pipes (11). The outlet port (13) of the microfluidic chip (6) is connected to the waste liquid collection tank (7).

4. The fluid bubble mass transfer simulation device based on a microfluidic chip according to claim 1, characterized in that: The microfluidic chip (6) is fabricated using an etching process.

5. A method for simulating intrafluid bubble mass transfer based on a microfluidic chip using the device described in any one of claims 1-4, characterized in that, Includes the following steps: Step S1: First, the microfluidic chip (6) is fabricated using an etching process, and an organic solvent for staining is prepared; Step S2: Next, gas and liquid are injected into the microfluidic chip (6) using the gas-liquid mixing module (9) to form bubbles inside the microfluidic chip (6); Step S3: Then, fix the microfluidic chip (6) onto the microfluidic chip fixing module (17); Step S4: Observe the redistribution evolution of bubbles in the microfluidic chip (6) under the influence of gravitational instability under microgravity or hypergravity conditions, and obtain the law of maturation and mass transfer of bubbles under microgravity or hypergravity conditions.

6. The method for simulating mass transfer of bubbles in fluid based on a microfluidic chip according to claim 5, characterized in that: The specific steps of step S2 are as follows: First, the prepared microfluidic chip (6) is placed on the stage of the microscope (8), and the dyed organic solvent is injected into the organic solvent collection tube (5). The carbon dioxide collection bottle (1) and the organic solvent collection tube (5) in the gas-liquid mixing module (9) are used to input gas and liquid with stable pressure into the microfluidic chip (6). After the liquid and gas are mixed, bubbles are formed and injected into the microfluidic chip (6) through the diversion tube (11). The presence of bubbles in the microfluidic chip (6) is monitored in real time by the microscope (8). The preparation of the microfluidic chip (6) is completed when the bubbles exist in the pores of the microfluidic chip (6) in the form of residual capture.

7. The method for simulating mass transfer of bubbles in fluid based on a microfluidic chip according to claim 5, characterized in that: The specific steps of step S3 are as follows: The prepared microfluidic chip (6) is removed from the stage of the microscope (8) and installed on the microfluidic chip fixing module (17). The guide tube (19) connected to the injection port (12) of the microfluidic chip (6) is sealed and clamped by the sealing clamp (21) so that the inside of the microfluidic chip (6) is in a closed environment. After a preset time, the guide tube (19) between the sealing clamp (21) and the pressure controller (4) is cut off.

8. The method for simulating mass transfer of bubbles in fluid based on a microfluidic chip according to claim 5, characterized in that: Under microgravity conditions, the specific steps of step S4 are as follows: Adjust the microfluidic chip (6) to a preset tilt angle, observe the mass transfer law of bubbles in the microfluidic chip (6) under microgravity conditions, and then obtain the law of mass transfer of bubbles under microgravity influence under real working conditions. Under hypergravity conditions, the specific steps of step S4 are as follows: The microfluidic chip fixing module (17) with the microfluidic chip (6) installed is placed on the basket of the centrifuge. The centrifuge is started. When the centrifugal acceleration reaches N times the gravitational acceleration and stabilizes, the mass transfer law of the bubbles in the microfluidic chip (6) under Ng hypergravity conditions is observed, so as to obtain the law of mass transfer of the bubbles under hypergravity under real working conditions.

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