Condensing equipment for distillation separation of medical intermediates

Abstract

The invention relates to the technical field of medicine production, in particular to condensing equipment for distillation separation of medical intermediates, which comprises a condensing tank, a refrigerant feeding pipe mounted on the lower side of the condensing tank and a refrigerant discharging pipe mounted on the upper side of the condensing tank, the condensation pipe assembly comprises a plurality of spiral condensation pipes, a feeding pipeline and a liquid outlet pipe, the feeding pipeline is arranged on the side, away from the refrigerant inlet pipe, of the condensation tank, the spiral condensation pipes are arranged downwards in a spiral mode, the multiple spiral condensation pipes are arranged in an up-down parallel mode, and the liquid outlet pipe is arranged among the multiple spiral condensation pipes; a flow guide ring layer is arranged on the inner side of the condensation pipe, a plurality of annular condensation grooves which are arranged in parallel up and down are formed in the flow guide ring layer, a flow guide cavity is formed in the flow guide ring layer, and a plurality of spraying openings communicated with the flow guide cavity are annularly formed in the annular condensation grooves. The contact time of a refrigerant and the spiral condensation pipe is prolonged, and therefore the condensation efficiency is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of pharmaceutical production, and particularly relates to a condensation device for distillation separation of pharmaceutical intermediates. Background Art

[0002] During the distillation separation of pharmaceutical intermediates, the role of the condensation device is to cool and convert the gaseous substances generated by distillation into liquids, so as to achieve the separation and purification of the target products. The pharmaceutical intermediate distillation condensation device needs to be selected from various condensers such as spiral condensation tubes or shell-and-tube condensers according to physical properties, scale and safety requirements.

[0003] The patent with the publication number CN220912073U discloses a shell-and-tube condenser for pharmaceutical intermediate production, which includes a condenser main body and shock-proof springs. The inner wall of the condenser main body is hollowed out. A plurality of condensation tubes are fixedly connected to the inner wall of the condenser main body. A plurality of pads are respectively fixedly connected to both sides of the condensation tubes. A plurality of air outlet holes are formed in the pads. A plurality of shock-proof springs are fixedly connected to the outer wall of the condenser main body.

[0004] The patent with the publication number CN221099407U discloses a condenser for pharmaceutical intermediate production, which includes a condenser body. A rotary motor is fixedly installed on one side of the condenser body. The output end of the rotary motor is fixedly connected to a screw rod. A first slider is threadedly connected to the outer side wall of the screw rod. A heat dissipation fan is fixedly connected to one side of the first slider, improving the cooling effect and preventing the existing equipment from only cooling one position.

[0005] When cooling the gaseous substances of pharmaceutical intermediates through a refrigerant, in order to ensure the heat exchange between the refrigerant and the gaseous substances, the refrigerant is usually introduced from below. However, since the refrigerant is introduced unidirectionally through the inlet pipe, it is easy to cause uneven distribution of the refrigerant, resulting in different heat absorption effects of the gaseous substances at different positions and affecting the condensation effect. Summary of the Invention

[0006] The purpose of the present invention is to solve the disadvantages that in the prior art, the refrigerant is introduced unidirectionally through the inlet pipe, which is easy to cause uneven distribution of the refrigerant, resulting in different heat absorption effects of the gaseous substances at different positions and affecting the condensation effect, and to propose a condensation device for distillation separation of pharmaceutical intermediates.

[0007] In order to achieve the above purpose, the present invention adopts the following technical scheme: A condensation device for distillation separation of a pharmaceutical intermediate, comprising: a condensation tank, a refrigerant feed pipe installed on the lower side of the condensation tank, and a refrigerant discharge pipe installed on the upper side of the condensation tank. A condensation pipe assembly is arranged inside the condensation tank. The condensation pipe assembly includes a plurality of spiral condensation pipes, a feed pipe, and a liquid discharge pipe. The feed pipe is arranged on one side of the condensation tank away from the refrigerant inlet pipe. The spiral condensation pipes are arranged spirally downward, and a plurality of the spiral condensation pipes are arranged parallel to each other up and down, and the feed ends are communicated with the feed pipe. The liquid discharge pipe is arranged between a plurality of spiral condensation pipes, and the discharge ends of the plurality of spiral condensation pipes are communicated with the liquid discharge pipe; A flow guiding ring layer is arranged inside the condensation pipe. A plurality of annular condensation grooves arranged parallel to each other up and down are opened inside the flow guiding ring layer. A flow guiding cavity is opened inside the flow guiding ring layer. A plurality of spray outlets communicated with the flow guiding cavity are annularly opened on the annular condensation grooves.

[0008] Preferably, the feed pipe includes a material guiding pipe and a shunt pipe. The material guiding pipe is fixedly installed on the side of the condensation pipe. The shunt pipe is fixedly connected to the end of the material guiding pipe, and the feed ends of a plurality of spiral condensation pipes are arranged parallel to each other up and down on the material guiding pipe.

[0009] Preferably, an opening is opened on one side of the flow guiding cavity close to the refrigerant feed pipe. A partition is fixedly connected inside the refrigerant feed pipe. The partition divides the refrigerant feed pipe into upper and lower parts. The upper part enters the inside of the flow guiding cavity, and the lower part enters the inside of the condensation tank.

[0010] Preferably, the spray outlets are arranged obliquely to spray the refrigerant horizontally obliquely, and the width of the inlet end of the spray outlet located inside the flow guiding cavity is greater than the width of the spray end of the spray outlet located on the annular condensation groove.

[0011] Preferably, a collection assembly is arranged at the upper end of the liquid discharge pipe. The collection assembly is used to collect the gaseous intermediate that is not completely condensed inside the spiral condensation pipe.

[0012] Preferably, the collection assembly includes a dish-shaped pipe and a collection spiral pipe. The dish-shaped pipe is fixedly connected to the upper end of the liquid discharge pipe. The collection spiral pipe is arranged on the side of the upper end of the dish-shaped pipe.

[0013] Preferably, a rotation assembly is arranged inside the dish-shaped pipe. The rotation assembly includes a rotation shaft, an impeller, and a plurality of magnetic blocks. The upper end of the rotation shaft is rotatably installed on the top wall of the dish-shaped pipe. The impeller is arranged horizontally and is fixedly connected to the bottom end of the rotation shaft in the middle. Magnetic blocks are arranged between a plurality of blades of the impeller. A plurality of the magnetic blocks are annularly and fixedly connected to both sides of the upper end of the dish-shaped pipe and generate a repulsive force with the magnetic blocks on the impeller.

[0014] Preferably, a scraping assembly is arranged below the impeller. The scraping assembly is used to scrape the liquid on the inner wall of the liquid discharge pipe.

[0015] Preferably, the scraping assembly includes a connecting pipe and a scraping strip. The connecting pipe is fixedly connected to the middle of the bottom surface of the impeller and sleeved inside the liquid outlet pipe. The scraping strip is spirally sleeved outside the connecting pipe.

[0016] Preferably, a plurality of separation openings are annularly formed at a position of the connecting pipe close to the discharge end of the spiral condenser tube. The bottom of the connecting pipe is open, and a plurality of air outlets are formed at the upper end.

[0017] Compared with the prior art, the beneficial effects of the present invention are as follows: 1. A plurality of spray outlets form an annular spray ring, so that the refrigerant is evenly distributed inside the annular condensation tank. A plurality of rotating flow layers are formed inside the plurality of annular condensation tanks. The rapid replacement of the refrigerant inside the rotating flow layer completes the heat exchange of the spiral condenser tube. At the same time, the rotating flow layer will play a certain blocking effect on the upward moving condensate, extending the contact time between the refrigerant and the spiral condenser tube, thereby improving the condensation efficiency; 2. By providing an additional collecting spiral tube above the liquid outlet pipe, the gas that has not been condensed inside each spiral condenser tube is collected and then condensed, thereby avoiding the situation of gaseous accumulation and inability to be quickly condensed, ensuring the transfer of uncondensed gaseous substances, ensuring the normal introduction of intermediate gaseous substances, and improving the condensation efficiency; 3. The gaseous intermediate accumulates inside the disc-shaped tube. As the gaseous intermediate continuously accumulates, it will generate a thrust on the obliquely arranged impeller, playing a role in promoting the rotation of the impeller. After the impeller starts to rotate, the magnetic block on the rotating impeller will have a repulsive force with the magnetic block, thereby driving the impeller to rotate, causing the impeller to generate an upward gas flow, so that the gaseous intermediate inside the liquid outlet pipe can be quickly transferred upward, and at the same time realizing the rapid separation of the condensate and the gaseous intermediate; 4. The rotation of the impeller drives the connecting pipe to rotate, thereby driving the scraping strip to rotate through the rotating connecting pipe. The inner wall of the liquid outlet pipe is scraped and cleaned by the scraping strip to avoid contamination between drugs; 5. By sleeving the connecting pipe inside the liquid outlet pipe to form a double-layer structure inside, since the weight of the liquid intermediate is relatively large, it will move along the inner wall of the liquid outlet pipe, while the gaseous intermediate will move upward, and the upward gas flow generated by the impeller will drive the gaseous intermediate to move through the separation opening into the connecting pipe, thereby realizing liquid-gas separation and avoiding the liquid intermediate from blocking and heat exchanging with the gas intermediate. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a front structural schematic diagram of a condensation device for distillation separation of pharmaceutical intermediates proposed by the present invention; Figure 2 It is a cross-sectional structural schematic diagram of a condensation device for distillation separation of pharmaceutical intermediates proposed by the present invention; Figure 3 The internal structure schematic diagram of a condensation device for distillation separation of a pharmaceutical intermediate proposed by the present invention; Figure 4 The structural schematic diagram of a condenser tube assembly of a condensation device for distillation separation of a pharmaceutical intermediate proposed by the present invention; Figure 5 The structural schematic diagram of a diversion ring layer of a condensation device for distillation separation of a pharmaceutical intermediate proposed by the present invention; Figure 6 The schematic diagram of the flow direction of the spray outlet of a condensation device for distillation separation of a pharmaceutical intermediate proposed by the present invention; Figure 7 The structural schematic diagram of a collection assembly of a condensation device for distillation separation of a pharmaceutical intermediate proposed by the present invention; Figure 8 The structural schematic diagram of a rotating assembly of a condensation device for distillation separation of a pharmaceutical intermediate proposed by the present invention; Figure 9 The structural schematic diagram of a scraping assembly of a condensation device for distillation separation of a pharmaceutical intermediate proposed by the present invention.

[0019] In the figure: 1, condensation tank; 2, refrigerant feed pipe; 3, condenser tube assembly; 31, spiral condenser tube; 32, feed pipeline; 321, guide pipe; 322, shunt pipe; 33, liquid outlet pipe; 4, diversion ring layer; 5, annular condensation tank; 6, spray outlet; 7, collection assembly; 71, dish-shaped pipe; 72, collection spiral pipe; 8, rotating assembly; 81, rotating shaft; 82, impeller; 83, magnetic block; 9, scraping assembly; 91, connecting pipe; 92, scraping bar; 10, partition board; 11, separation port. Detailed implementation manners

[0020] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments.

[0021] The terms such as "upper", "lower", "left", "right", "middle" and "one" cited in the present invention are only for the convenience of clear narration, rather than to limit the scope of implementation of the present invention. The change or adjustment of their relative relationship, without substantial change in the technical content, should also be regarded as the scope of implementation of the present invention.

[0022] Refer to Figures 1-9, A condensation device for distillation separation of a pharmaceutical intermediate, comprising: a condensation tank 1, a refrigerant feed pipe 2 installed on the lower side of the condensation tank 1, and a refrigerant discharge pipe installed on the upper side of the condensation tank 1. A condensation pipe assembly 3 is arranged inside the condensation tank 1. The condensation pipe assembly 3 includes a plurality of spiral condensation pipes 31, a feed pipe 32, and a liquid discharge pipe 33. The feed pipe 32 is arranged on the side of the condensation tank 1 away from the refrigerant inlet pipe. The spiral condensation pipes 31 are arranged spirally downward. The plurality of spiral condensation pipes 31 are arranged parallel to each other up and down, and the feed ends are communicated with the feed pipe 32. The liquid discharge pipe 33 is arranged between the plurality of spiral condensation pipes 31, and the discharge ends of the plurality of spiral condensation pipes 31 are communicated with the liquid discharge pipe 33; A diversion ring layer 4 is arranged inside the condensation pipe. A plurality of annular condensation grooves 5 arranged parallel to each other up and down are opened inside the diversion ring layer 4. A diversion cavity is opened inside the diversion ring layer 4. A plurality of spray outlets 6 communicated with the diversion cavity are annularly opened on the annular condensation grooves 5.

[0023] In the embodiments applying the above technical solutions, in existing condensation devices, the refrigerant is mostly introduced from the refrigerant feed pipe 2 below. However, since the refrigerant absorbs heat from below, the refrigerant above cannot absorb a large amount of heat, resulting in a reduction in the condensation effect of the pharmaceutical intermediate inside the upper condensation spiral pipe. Similarly, the refrigerant replacement near the refrigerant feed pipe 2 is faster, and the condensation replacement away from the refrigerant feed pipe 2 is slower, and the refrigerant distribution is uneven, thus affecting the overall heat exchange effect; The spirally downwardly arranged condensation spiral pipe can quickly transfer the internally condensed liquid intermediate downward, extend the retention time of the gaseous intermediate inside the condensation spiral pipe, and improve the separation between the intermediates; At the same time, the refrigerant introduced into the condensation tank 1 is divided into two parts. The plurality of spray outlets 6 form an annular spray ring, so that the refrigerant is evenly distributed inside the annular condensation grooves 5. A plurality of rotating flow layers are formed inside the plurality of annular condensation grooves 5. The rapid replacement of the refrigerant inside the rotating flow layer completes the heat exchange with the spiral condensation pipes 31. At the same time, the rotating flow layer will play a certain blocking effect on the upward moving condensation, extend the contact time between the refrigerant and the spiral condensation pipes 31, and thus improve the condensation efficiency.

[0024] The preferred technical solution in this embodiment: Refer to Figure 4 , The feed pipe 32 includes a material guiding pipe 321 and a shunt pipe 322. The material guiding pipe 321 is fixedly installed on the side of the condensation pipe. The shunt pipe 322 is fixedly connected to the end of the material guiding pipe 321, and the feed ends of the plurality of spiral condensation pipes 31 are arranged parallel to each other up and down on the material guiding pipe 321; The gaseous substance of the pharmaceutical intermediate is introduced into the inside of the shunt pipe 322 through the material guiding pipe 321, and the gaseous substance is dispersed into a plurality of spiral condensing pipes 31 through the shunt pipe 322, thereby shunting and condensing the gaseous substance, improving the condensing efficiency of a large amount of intermediate gaseous substances, and being suitable for the condensing treatment of a large amount of pharmaceutical intermediates.

[0025] Refer to Figure 2 and Figure 5 One side of the diversion cavity close to the refrigerant inlet pipe 2 is provided with an opening. A partition 10 is fixedly connected inside the refrigerant inlet pipe 2. The partition 10 divides the refrigerant inlet pipe 2 into upper and lower parts. The upper part enters the inside of the diversion cavity, and the lower part enters the inside of the condensing tank 1. Most of the existing condensing devices introduce the refrigerant from below. Through the upward movement of the refrigerant, heat exchange with the condensing pipe is completed. However, since the refrigerant absorbs heat from below, the heat inside the refrigerant moving to the upper part is relatively high, and it is impossible to effectively complete the heat exchange with the upper condensing pipe. At the same time, due to the guiding introduction through the pipeline, such a method is likely to cause the refrigerant near the pipeline to exchange heat faster, resulting in the refrigerant far from the inlet pipe being unable to be quickly replaced, and the refrigerant is unevenly distributed, thus affecting the heat exchange effect. The refrigerant inlet pipe 2 is directly divided into upper and lower parts by the partition 10. During the process of introducing the refrigerant, the refrigerant is evenly introduced into the diversion cavity of the diversion ring layer and the inside of the condensing tank 1. The part introduced into the diversion cavity is ejected through the multi-layer ejection ports 6, and the refrigerant exchange is accelerated inside the plurality of annular condensing grooves 5. The refrigerant introduced into the lower part into the condensing tank 1 is used to fill the inside of the condensing tank 1, continuously pushing the refrigerant upward and pushing the refrigerant with heat exchange completed upward for export.

[0026] Refer to Figures 5-6 The ejection port 6 is inclined, ejecting the refrigerant horizontally and obliquely, and the width of the inlet end of the ejection port 6 located inside the diversion cavity is greater than the width of the ejection end of the ejection port 6 located on the annular condensing groove 5. The ejection port 6 is inclined, and at the same time, the inlet width is greater than the width of the ejection port 6. When the refrigerant enters the ejection port 6 through the diversion cavity, through the ejection port 6 from wide to narrow, the extrusion ejection of the refrigerant is realized. The plurality of ejection ports 6 form an annular ejection ring, thereby driving the refrigerant to rotate inside the annular condensing groove 5, making the refrigerant evenly distributed inside the annular condensing groove 5. A plurality of rotating flow layers are formed inside the plurality of annular condensing grooves 5. The rotating flow layers perform heat exchange on the spiral condensing pipe 31, and at the same time, the rotating flow layers will play a certain blocking effect on the upward movement of the condensate, prolonging the contact time between the refrigerant and the spiral condensing pipe 31.

[0027] Refer to Figure 7 A collection assembly 7 is provided at the upper end of the liquid outlet pipe 33. The collection assembly 7 is used to collect the gaseous intermediate that is not completely condensed inside the spiral condensing pipe 31. The collection component 7 includes a dish-shaped tube 71 and a collection spiral tube 72. The dish-shaped tube 71 is fixedly connected to the upper end of the liquid outlet pipe 33, and the collection spiral tube 72 is arranged on the upper side of the dish-shaped tube 71.

[0028] During the condensation process, due to the heat exchange efficiency problem, there will still be some gaseous intermediates that have not completed heat exchange and condensation. As a result, these gaseous intermediates will accumulate inside the liquid outlet pipe 33, causing the internal pressure of the liquid outlet pipe 33 to increase, affecting the entry of gas inside the spiral condensation pipe 31, and reducing the condensation efficiency.

[0029] By arranging an additional collection spiral tube 72 above the liquid outlet pipe 33, the gas that has not completed condensation inside each spiral condensation pipe 31 is collected and re-condensed, thus avoiding the occurrence of gaseous accumulation and the situation where rapid condensation cannot occur, ensuring the transfer of uncondensed gaseous substances, ensuring the normal introduction of intermediate gaseous substances, and improving the condensation efficiency.

[0030] Refer to Figure 8 As shown in the figure, a rotating component 8 is arranged inside the dish-shaped tube 71. The rotating component 8 includes a rotating shaft 81, an impeller 82, and a plurality of magnetic blocks 83. The upper end of the rotating shaft 81 is rotatably installed on the top wall of the dish-shaped tube 71. The impeller 82 is horizontally arranged, and the middle part is fixedly connected to the bottom end of the rotating shaft 81. There are magnetic blocks between the blades of the impeller 82. A plurality of the magnetic blocks 83 are annularly and fixedly connected to both sides of the upper end of the dish-shaped tube 71, and a repulsive force is generated between them and the magnetic blocks on the impeller 82. When the gaseous intermediate that has not completed condensation moves upward and transfers into the dish-shaped tube 71, the gaseous intermediate accumulates inside the dish-shaped tube 71. As the gaseous intermediate continuously accumulates, a thrust will be generated on the obliquely arranged impeller 82, which plays a role in promoting the rotation of the impeller 82. After the impeller 82 starts to rotate, the magnetic blocks on the rotating impeller 82 will have a repulsive force with the magnetic blocks 83, thereby driving the impeller 82 to rotate, causing the impeller 82 to generate an upward gas flow, so that the gaseous intermediate inside the liquid outlet pipe 33 can be quickly transferred upward, and at the same time, the rapid separation of the condensate and the gaseous intermediate is realized, avoiding the condensate dripping from the upper spiral condensation pipe 31 from blocking the upward moving gaseous intermediate of the lower spiral condensation pipe 31.

[0031] Refer to Figure 9 As shown in the figure, a scraping component 9 is arranged below the impeller 82. The scraping component 9 is used to scrape the liquid on the inner wall of the liquid outlet pipe 33. The scraping component 9 includes a connecting pipe 91 and a scraping strip 92. The connecting pipe 91 is fixedly connected to the middle part of the bottom surface of the impeller 82 and is sleeved inside the liquid outlet pipe 33. The scraping strip 92 is spirally sleeved on the outside of the connecting pipe 91. A plurality of separation ports 11 are annularly provided at a position of the connecting pipe 91 close to the discharge end of the spiral condensing pipe 31. The bottom of the connecting pipe 91 is an opening, and a plurality of air outlets are provided at the upper end.

[0032] In the early stage and the late stage of condensation, the condensation rate of the condensate is slow, resulting in some condensate adhering to the inner wall of the liquid outlet pipe 33 and unable to accumulate and flow downward. In order to avoid the mixing of the previous pharmaceutical intermediate into the latter pharmaceutical intermediate during the conversion condensation of various pharmaceutical intermediates, it is necessary to avoid the liquid residue of the previous traditional Chinese medicine intermediate remaining inside the liquid outlet pipe 33 and to fixedly clean the inner wall of the liquid outlet pipe 33 during the condensation process, so as to avoid cross-contamination between drugs. The rotation of the impeller 82 drives the connecting pipe 91 to rotate, and thus the rotating connecting pipe 91 drives the scraping strip 92 to rotate, and the inner wall of the liquid outlet pipe 33 is scraped and cleaned by the scraping strip 92.

[0033] At the same time, during the condensation process, in order to prevent the condensate dripping from the upper spiral condensing pipe 31 from blocking the gaseous intermediate moving upward in the lower spiral condensing pipe 31, a connecting pipe 91 is sleeved inside the liquid outlet pipe 33 to form a double-layer structure inside. Since the weight of the liquid intermediate is large, it will move along the inner wall of the liquid outlet pipe 33, while the gaseous intermediate will move upward, and the upward gas flow generated by the impeller 82 will drive the gaseous intermediate to move into the connecting pipe 91 through the separation ports 11, thereby realizing liquid-gas separation and avoiding the blocking and heat exchange of the liquid intermediate to the gas intermediate.

[0034] The above is only a preferred specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution and inventive concept of the present invention, makes equivalent substitutions or changes, and should be covered by the protection scope of the present invention.

Claims

1. A condensation device for distillation separation of a pharmaceutical intermediate, comprising: A condensation tank, a refrigerant inlet pipe installed on the lower side of the condensation tank, and a refrigerant outlet pipe installed on the upper side of the condensation tank, characterized in that a condensation pipe assembly is arranged inside the condensation tank, and the condensation pipe assembly includes a plurality of spiral condensation pipes, a feed pipe and a liquid outlet pipe. The feed pipe is arranged on one side of the condensation tank away from the refrigerant inlet pipe. The spiral condensation pipes are arranged spirally downward, and a plurality of the spiral condensation pipes are arranged parallel to each other up and down, and the feed ends are communicated with the feed pipe. The liquid outlet pipe is arranged between a plurality of spiral condensation pipes, and the discharge ends of a plurality of spiral condensation pipes are communicated with the liquid outlet pipe; A diversion ring layer is arranged inside the condensation pipe. A plurality of annular condensation grooves arranged parallel to each other up and down are opened inside the diversion ring layer. A diversion cavity is opened inside the diversion ring layer. A plurality of spray outlets communicated with the diversion cavity are annularly opened on the annular condensation grooves.

2. The condensation device for distillation separation of a pharmaceutical intermediate according to claim 1, characterized in that, The feed pipe includes a material guide pipe and a shunt pipe. The material guide pipe is fixedly installed on the side of the condensation pipe. The shunt pipe is fixedly connected to the end of the material guide pipe, and the feed ends of a plurality of spiral condensation pipes are arranged parallel to each other up and down on the material guide pipe.

3. The condensation device for distillation separation of a pharmaceutical intermediate according to claim 1, characterized in that, An opening is formed on one side of the diversion cavity close to the refrigerant inlet pipe. A partition is fixedly connected inside the refrigerant inlet pipe. The partition divides the refrigerant inlet pipe into upper and lower parts. The upper part enters the inside of the diversion cavity, and the lower part enters the inside of the condensation tank.

4. A condensation device for distillation separation of a pharmaceutical intermediate according to claim 1, characterized in that, The spray outlets are arranged obliquely to spray the refrigerant horizontally and obliquely, and the width of the inlet end of the spray outlet inside the diversion cavity is greater than the width of the spray end of the spray outlet on the annular condensation groove.

5. A condensation device for distillation separation of a pharmaceutical intermediate according to claim 1, characterized in that, A collection assembly is arranged at the upper end of the liquid outlet pipe. The collection assembly is used to collect the gaseous intermediate that is not completely condensed inside the spiral condensation pipe.

6. The condensation device for distillation separation of a pharmaceutical intermediate according to claim 5, characterized in that, The collection assembly includes a dish-shaped pipe and a collection spiral pipe. The dish-shaped pipe is fixedly connected to the upper end of the liquid outlet pipe. The collection spiral pipe is arranged on the side of the upper end of the dish-shaped pipe.

7. The condensation device for distillation separation of a pharmaceutical intermediate according to claim 6, characterized in that, A rotation assembly is arranged inside the dish-shaped pipe. The rotation assembly includes a rotation shaft, an impeller and a plurality of magnetic blocks. The upper end of the rotation shaft is rotatably installed on the top wall of the dish-shaped pipe. The impeller is arranged horizontally and fixedly connected to the bottom end of the rotation shaft in the middle. Magnetic blocks are arranged between a plurality of blades of the impeller. A plurality of the magnetic blocks are fixedly connected to both sides of the upper end of the dish-shaped pipe in a ring shape and generate a repulsive force with the magnetic blocks on the impeller.

8. A condensation device for distillation separation of a pharmaceutical intermediate according to claim 7, characterized in that, A scraping assembly is arranged below the impeller. The scraping assembly is used to scrape the liquid on the inner wall of the liquid outlet pipe.

9. A condensation device for distillation separation of a pharmaceutical intermediate according to claim 8, characterized in that, The scraping assembly includes a connecting pipe and a scraping strip. The connecting pipe is fixedly connected to the middle of the bottom surface of the impeller and sleeved inside the liquid outlet pipe. The scraping strip is spirally sleeved on the outside of the connecting pipe in a ring shape.

10. The condensation device for distillation separation of a pharmaceutical intermediate according to claim 9, wherein, A plurality of separation openings are annularly formed at the position of the connecting pipe close to the discharge end of the spiral condensation pipe. The bottom of the connecting pipe is an opening, and a plurality of air outlets are formed at the upper end.

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