Aerosol for preventing and killing pests and acarids and method for preventing and killing pests and acarids

Abstract

The present invention provides an aerosol for controlling pests and acarids, which has an excellent control effect on various pests and acarids. An aerosol for controlling pests and acarids, which is obtained by filling an aerosol container provided with a quantitative injection valve with a propellant and an aerosol stock solution containing (A) a component for controlling pests and acarids and (B) a synergist, and wherein the synergist (B) is N-(2-ethylhexyl)-bicyclo [2, 2, 1]-hept-5-ene-2, 2, 1]-hept-5-ene-2, 2, 1]-hept-5-ene-2, 2, 1]-hept-5-ene-2, 2, 1]-hept-5-ene-2, 2, 1]-hept-5-ene-2, 2, 1]-hept-5-ene-2, 2, 1]-hept-5-ene-2, 2, 1]-hept-5 and 2, 3-dicarboximide is used as a raw material.

Description

Technical Field

[0001] The present invention relates to an aerosol for controlling pests and ticks / mites, which is formed by filling an aerosol stock solution containing components for controlling pests and ticks / mites and a synergist and a propellant into an aerosol container equipped with a metering spray valve; and also relates to a method for controlling pests and ticks / mites using the aerosol for controlling pests and ticks / mites. Background Art

[0002] There has been known a metering spray type aerosol formed by filling an aerosol stock solution containing a control component such as a pyrethroid compound and a propellant into an aerosol container equipped with a metering spray valve. Moreover, a method for controlling pests using such a metering spray type aerosol has been continuously implemented.

[0003] For example, there has been proposed a method for repelling crawling pests, in which an aerosol composition is sprayed downward from a metering spray type aerosol product filled with an aerosol composition containing a stock solution (aerosol stock solution) containing a component for repelling crawling pests and a propellant (see Patent Document 1).

[0004] Prior Art Documents

[0005] Patent Documents

[0006] Patent Document 1: Japanese Patent Application Laid-Open No. 2019-104708 Summary of the Invention

[0007] Problems to be Solved by the Invention

[0008] Regarding the pest control method described in Patent Document 1, although the number of pests is reduced by the repellent effect of the aerosol product, the repellent effect cannot be said to be sufficiently high, and the lethal effect on crawling pests cannot be said to be sufficient either.

[0009] As such, in conventional metering spray type aerosols, it is difficult to sufficiently exert control effects such as knockdown effect, lethal effect, and repellent effect on pests such as cockroaches and ticks / mites such as house dust mites, and thus there is a need for a metering spray type aerosol having excellent control effects on these pests and ticks / mites.

[0010] The present invention has been completed in view of the above circumstances, and an object thereof is to provide an aerosol for controlling pests and ticks / mites and a method for controlling pests and ticks / mites, which have excellent control effects on various pests and ticks / mites.

[0011] Means for Solving the Problems

[0012] The inventors of the present invention conducted intensive studies and reviews to solve the above problems, and as a result, found that by using a pest and tick / mite control component in combination with N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide as a synergist, an excellent pest and tick / mite control effect can be exerted on various pests and tick / mites, and thus the present invention was completed.

[0013] That is, the characteristic configuration of the aerosol for pest and tick / mite control according to the present invention for solving the above problems is as follows: It is an aerosol for pest and tick / mite control obtained by filling an aerosol stock solution containing (A) a pest and tick / mite control component and (B) a synergist and a propellant into an aerosol container equipped with a metering valve, wherein the above-mentioned (B) synergist is N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide.

[0014] In the aerosol for pest and tick / mite control according to this configuration, in the aerosol for pest and tick / mite control obtained by filling an aerosol stock solution containing (A) a pest and tick / mite control component and (B) a synergist and a propellant into an aerosol container equipped with a metering valve, by selecting N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide as the (B) synergist, an excellent pest and tick / mite control effect can be exerted on various pests and tick / mites.

[0015] In the aerosol for pest and tick / mite control according to the present invention, the above-mentioned N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide is preferably a mixture having an isomer ratio (Endo / Exo) of Endo type and Exo type of 30 / 70 to 70 / 30 in terms of molar ratio.

[0016] In the aerosol for pest and tick / mite control according to this configuration, by using a mixture having an isomer ratio (Endo / Exo) within the above-mentioned appropriate range as N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide, the pest and tick / mite control effect on various pests and tick / mites can be improved.

[0017] In the aerosol for pest and tick / mite control according to the present invention, the above-mentioned (A) pest and tick / mite control component preferably contains a non-volatile pyrethroid compound having a vapor pressure of less than 1×10 -4 mmHg (1.33×10 -5 kPa) at 30°C.

[0018] In the aerosol for pest and tick / mite control according to this configuration, by using a compound having a vapor pressure of less than 1×10 -4A non-volatile pyrethroid compound in mmHg can improve the control effect against various pests and ticks.

[0019] In the aerosol for controlling pests and ticks according to the present invention, the above non-volatile pyrethroid compound preferably contains phenothrin and / or permethrin.

[0020] For the aerosol for controlling pests and ticks according to this configuration, by using phenothrin and / or permethrin as the non-volatile pyrethroid compound, the control effect against various pests and ticks can be further improved.

[0021] In the aerosol for controlling pests and ticks according to the present invention, it is preferably configured such that 30% or more of the above component (A) for controlling pests and ticks adheres to the ground of the treatment space by mass 1 hour after spraying.

[0022] For the aerosol for controlling pests and ticks according to this configuration, since 30% or more of the component (A) for controlling pests and ticks adheres to the ground of the treatment space by mass 1 hour after spraying, it is natural that the control effect can be quickly exerted against various pests and ticks wandering on the ground, and the control effect can also be exerted against pests and ticks lurking in dark places such as furniture and / or electrical appliances.

[0023] In the aerosol for controlling pests and ticks according to the present invention, the release amount of the above component (A) for controlling pests and ticks into the atmosphere is preferably set to 0.1 - 50 mg / m 3 。

[0024] For the aerosol for controlling pests and ticks according to this configuration, by setting the release amount of the component (A) for controlling pests and ticks into the atmosphere to 0.1 - 50 mg / m 3 , regardless of the volume of the treatment space, the control effect against various pests and ticks can be further improved.

[0025] In the aerosol for controlling pests and ticks according to the present invention, the injection volume per injection of the above metering injection valve is preferably set to 0.1 - 3.0 mL.

[0026] For the aerosol for controlling pests and ticks according to this configuration, since the injection volume per injection of the metering injection valve is set to 0.1 - 3.0 mL, by injecting the aerosol for controlling pests and ticks one to several times, regardless of the volume of the treatment space, the control effect against various pests and ticks can be further improved.

[0027] In the aerosol for controlling pests and ticks according to the present invention, the injection force at a spraying distance of 5 cm is preferably set to be 0.029 - 0.49 N at 25°C.

[0028] The aerosol for controlling pests and ticks according to this configuration, by making the jet force at a jet distance of 5 cm be 0.029 to 0.49 N at 25°C, most of the components (A) for controlling pests and ticks ejected will rapidly settle and adhere to the ground of the treatment space, and the control effect on various pests and ticks can be further improved.

[0029] In the aerosol for controlling pests and ticks according to the present invention, the volume ratio (a / b) of the aerosol stock solution (a) to the propellant (b) is preferably set to 15 / 85 to 60 / 40.

[0030] The aerosol for controlling pests and ticks according to this configuration, since the volume ratio (a / b) of the aerosol stock solution (a) to the propellant (b) is set to 15 / 85 to 60 / 40, the control effect on various pests and ticks can be further improved.

[0031] In the aerosol for controlling pests and ticks according to the present invention, it is preferable to target crawling pests and / or household dust mites for control.

[0032] The aerosol for controlling pests and ticks according to this configuration can provide a quantitative spray type aerosol that targets crawling pests and / or household dust mites for control.

[0033] In the aerosol for controlling pests and ticks according to the present invention, it is preferable to kill the above-mentioned crawling pests and / or household dust mites.

[0034] The aerosol for controlling pests and ticks according to this configuration, by being set to kill crawling pests and / or household dust mites, can also reliably control crawling pests and / or household dust mites that attempt to escape from the treatment space.

[0035] The characteristic configuration of the method for controlling pests and ticks according to the present invention for solving the above problems lies in: a method for controlling pests and ticks using an aerosol for controlling pests and ticks, which is formed by filling an aerosol stock solution containing (A) a component for controlling pests and ticks and (B) a synergist and a propellant into an aerosol container equipped with a quantitative spray valve, wherein the above-mentioned (B) synergist is N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide, and in this method, the above-mentioned aerosol for controlling pests and ticks is sprayed into the treatment space.

[0036] The method for controlling pests and mites according to this constitution uses an aerosol for controlling pests and mites, which is formed by filling an aerosol raw liquid containing (A) a component for controlling pests and mites and (B) a synergist and a propellant into an aerosol container equipped with a metering spray valve. When spraying this aerosol for controlling pests and mites into a treatment space, by selecting N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide as the (B) synergist, excellent control effects can be exerted on various pests and mites.

[0037] In the method for controlling pests and mites according to the present invention, it is preferable to spray the above aerosol for controlling pests and mites obliquely upward into the treatment space.

[0038] For the aerosol for controlling pests and mites according to this constitution, by spraying the aerosol for controlling pests and mites obliquely upward, the spray particles will spread widely in the air of the treatment space, and the (A) component for controlling pests and mites contained in the spray particles can settle and adhere to the ground of the treatment space. As a result, excellent control effects can be exerted on various pests and mites. Detailed implementation mode

[0039] The aerosol for controlling pests and mites and the method for controlling pests and mites of the present invention will be described below. However, it is not intended that the present invention is limited to the constitution described in the following embodiments. In addition, in this specification, the unit "w / v%" of the content is synonymous with "g / 100ml". When there is a description of a range "~" in this specification, the upper and lower limits are included. In addition, the unit of vapor pressure can be converted to "1 mmHg = 0.133 kPa", and the unit of spraying force can be converted to "1 gf = 0.0098 N".

[0040] <Aerosol for controlling pests and mites>

[0041] The aerosol for controlling pests and mites of this embodiment is an aerosol formed by filling an aerosol raw liquid containing a component for controlling pests and mites and a synergist and a propellant into an aerosol container equipped with a metering spray valve. A well-known spray valve can be used as the metering spray valve.

[0042] <Controlling pests and mites>

[0043] "Controlling pests and mites" means controlling including repelling in addition to the knockdown effect and lethal effect on pests and mites. The aerosol for controlling pests and mites of this embodiment preferably kills crawling pests and / or house dust mites. By setting it to kill crawling pests and / or house dust mites, crawling pests and / or house dust mites that want to escape from the treatment space can also be reliably controlled.

[0044] <Aerosol collagen solution>

[0045] The aerosol collagen solution is prepared in the form of a composition containing components for controlling pests and ticks / mites and a synergist in a solvent. The aerosol collagen solution and a propellant are sealed in a pressure-resistant container.

[0046] (Components for controlling pests and ticks / mites)

[0047] The components for controlling pests and ticks / mites are components having pest and tick / mite control activity. Examples of the components for controlling pests and ticks / mites include pyrethroid compounds such as phenothrin, cyphenothrin, permethrin, cypermethrin, flucythrinate, bifenthrin, fenpropathrin, tetramethrin, ethofenprox, imiprothrin, resmethrin, transfluthrin, metofluthrin, profluthrin, empenthrin (Japanese: terallethrin), furamethrin, momfluorothrin, d-tetramethrin, meperfluthrin, heptafluthrin, deltamethrin, tetramethrin, allethrin, tetramethrin, propargite, natural pyrethrin, etc.; silicone compounds such as silafluofen; organophosphorus compounds such as dichlorvos, bromophos; carbamate compounds such as propoxur (Japanese: propoxur); neonicotinoid compounds such as dinotefuran, nitenpyram, and clothianidin; fipronil, indoxacarb, broflanilide, metaflumizone, amidoflumet, benzyl benzoate, phenyl salicylate, benzyl salicylate, dibutyl sebacate, dipropyl sebacate, dibutyl adipate, diethyl phthalate, dipropyl phthalate, dibutyl phthalate, citronellol, 3-iodo-2-propynyl butylcarbamate, diethyltoluamide, etc.

[0048] Among the components for controlling pests and ticks / mites, pyrethroid compounds are preferred, and pyrethroid compounds with a vapor pressure less than 1×10 -4 mmHg (1.33×10 -5 kPa) at 30°C are more preferred. Examples of the less volatile pyrethroid compounds include phenothrin, cyphenothrin, permethrin, cypermethrin, flucythrinate, bifenthrin, fenpropathrin, tetramethrin, ethofenprox, imiprothrin, resmethrin, etc., and phenothrin and / or permethrin are preferred. Thereby, the pest and tick / mite control effect can be further improved. The components for controlling pests and ticks / mites can be used alone or as a mixture of two or more. In addition, when there are optical isomers and geometric isomers due to asymmetric carbon in the acid component, alcohol part, etc. of the pyrethroid compound, each of them and any optional mixture are also included in the present invention.

[0049] The content of the pest control and acarid component in the aerosol stock solution is preferably 1.0 to 80.0 w / v%, more preferably 5.0 to 75.0 w / v%, and even more preferably 10.0 to 70.0 w / v%. By setting the content of the pest control and acarid component to the above appropriate range, the control effect on various pests and acarids can be further improved.

[0050] (Synergizer)

[0051] Although the synergist itself does not show an effect of controlling pests and mites, it is an agent that enhances the control effect of the components of the pest and mites by being used in combination (mixed) with the components of the pest and mites. In this embodiment, N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide is used as a synergist. Thus, excellent control effects can be exerted on various pests and mites.

[0052] Regarding N-(2-ethylhexyl)-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide, as a stereostructure (isomer), there are two isomers, the Endo form and the Exo form. Regarding N-(2-ethylhexyl)-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide, it is useful to use a mixture in which the isomer ratio (Endo / Exo) of the Endo form and the Exo form is adjusted to 30 / 70 to 70 / 30, preferably 40 / 60 to 60 / 40, in terms of molar ratio. However, the Endo form or the Exo form can also be used alone. The isomer ratio of the Endo form and the Exo form can be determined by the analytical method using liquid chromatography described in "Chiral high-performance liquid chromatography of N-octyl bicycloheptenedicarboximide and confirmatory studies using liquid chromatography-tandem mass spectrometry and two-dimensional nuclear magnetic resonance spectroscopy" in Journal of Chromatography A (Volume 864, 1999, pages 271-281). By adjusting the isomer ratio (Endo / Exo) to the above appropriate range, the control effect against various pests and ticks can be improved. In addition, the molecular weights of N-(2-ethylhexyl)-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide in the Endo form and the Exo form are equal, so the isomer ratio is equivalent to the mass ratio. Hereinafter, a manufacturing method of N-(2-ethylhexyl)-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide that can adjust the isomer ratio (Endo / Exo) to a specific range, that is, a method for adjusting the isomer ratio (Endo / Exo) will be described.

[0053] For example, by using Endo-type nadic anhydride (5-norbornene-2,3-dicarboxylic anhydride) in the following steps (1) to (3), a mixture of N-(2-ethylhexyl)-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide in which the Endo form and the Exo form coexist in a specific isomer ratio (Endo / Exo) can be obtained. Endo-type nadic anhydride (5-norbornene-2,3-dicarboxylic anhydride) is relatively inexpensive and suitable as a raw material.

[0054] Step (1): Isomerize Endo-type nadic anhydride (isomerization reaction). As a result, the nadic anhydride will be in a state where Endo-type and Exo-type coexist. Basically, the isomer ratio (Endo / Exo) can be adjusted in such an isomerization reaction.

[0055] Step (2): Condense the isomerization reaction product obtained in step (1) with 2-ethylhexylamine (condensation reaction). As a result, it will be in a state where Endo-type N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide and Exo-type N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide coexist.

[0056] Step (3): Distill N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide from the condensation reaction liquid containing the condensation reaction product obtained in step (2). As a result, N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide will be separated from the condensation reaction liquid containing unreacted substances, by-products, etc. in a state where Endo-type and Exo-type coexist. The isomer ratio (Endo / Exo) can also be further adjusted in this distillation.

[0057] In step (1), Endo-type nadic anhydride is added to the reaction vessel without adding an organic solvent or together with an organic solvent having a boiling point of 190 to 300 °C, and heated at 190 °C or higher for 30 minutes or more. As a result, a part of the Endo-type nadic anhydride will isomerize to produce Exo-type nadic anhydride. Generally, as the reaction time is extended, the ratio of Exo-type tends to increase. Therefore, by adjusting the reaction time, the isomer ratio (Endo / Exo) can be adjusted. For example, the isomer ratio (Endo / Exo) of Endo-type and Exo-type can be adjusted to the range of 30 / 70 to 70 / 30. In the case of not adding an organic solvent, a part of the nadic anhydride will sublime and adhere to the upper part of the reaction vessel, and the isomerization will also proceed in this adherent, so it can be included in the isomerization reaction product. As the organic solvent used in step (1), an aliphatic hydrocarbon solvent, an aromatic hydrocarbon solvent, an ester solvent, an ether solvent, etc. can be used, and kerosene is particularly preferred. Kerosene is suitable as the solvent used in the reactions in steps (1) and (2) and is easy to operate.

[0058] In step (2), the isomerization reaction solution containing the isomerization reaction product obtained in step (1) is cooled to room temperature. After cooling, 2-ethylhexylamine is added to the isomerization reaction solution. When an organic solvent is added in step (1), 2-ethylhexylamine is added alone to the isomerization reaction solution. When no organic solvent is added in step (1), 2-ethylhexylamine is added to the isomerization reaction solution together with water or an organic solvent (such as toluene, xylene) with a boiling point of 110 - 150°C. After adding 2-ethylhexylamine, by heating at 90 - 160°C for 30 minutes or more, a condensation reaction occurs between the isomerization reaction product obtained in step (1) and 2-ethylhexylamine. In this condensation reaction, the isomer ratio (Endo / Exo) of the Endo type and the Exo type does not change significantly. Therefore, the isomer ratio (Endo / Exo) can be basically determined by the isomerization reaction in step (1). In step (2), if water, an organic solvent (such as kerosene, toluene, xylene) is used, the nadic anhydride adhering to the upper part of the reaction vessel can be washed off, and it can be used for the condensation reaction, which can increase the yield of the reaction product. When water is added, the manufacturing safety can be improved. In addition, after the condensation reaction is completed, if necessary, the pH of the condensation reaction solution is adjusted to 5.5 - 7.0 using soda ash (sodium carbonate) for use in the next step (3).

[0059] In step (3), the condensation reaction solution containing the condensation reaction product obtained in step (2) is put into a distillation apparatus, and the condensation reaction product, i.e., N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide, is distilled out. The distillation temperature can be set to 160 - 170°C / 3 mmHg (160 - 170°C / 0.399 kPa). A usual distillation apparatus can be used for the distillation apparatus. In addition, by heating the N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide separated by distillation to 210°C or higher, the isomerization from the Endo type to the Exo type can be further promoted. In this way, the isomer ratio (Endo / Exo) of the Endo type and the Exo type can also be further adjusted in step (3).

[0060] Regarding the content of the synergist in the aerosol collagen solution, it is preferably 0.01 - 30.0 w / v%, more preferably 0.1 - 20.0 w / v%, and further preferably 0.5 - 10.0 w / v%. By setting the content of the synergist within the above appropriate range, the control effect on various pests and ticks can be further improved.

[0061] (Mixing ratio of the component for controlling pests and ticks and the synergist)

[0062] The mixing ratio (A / B) of the pest and tick mite control component (A) and the synergist (B) in the aerosol collagen solution is preferably 1 / 5 to 100 / 1, more preferably 1 / 4 to 100 / 1, further preferably 1 / 3 to 50 / 1, and particularly preferably 1 / 1 to 30 / 1 by mass ratio. By setting the mixing ratio (A / B) within the above appropriate range, the control effect on various pests and tick mites can be further improved.

[0063] (Solvent)

[0064] The aerosol collagen solution usually uses a stock solution in a state where the pest and tick mite control component and the synergist are dissolved or dispersed in an organic solvent or water as a solvent. Examples of the organic solvent include lower alcohols having 2 to 3 carbon atoms, normal alkanes (e.g., product names: Neothiozole, DA-1, etc.), isoparaffins (e.g., product names: ISOPAR M, ISOPAR G, ISOPAR H, ISOPAR L, IP SOLVENT 1620, IP SOLVENT 2028, IP SOLVENT 2835, IP Clean LX, Idemitsu SUPASOL FP25, Idemitsu SUPASOL LA25, ISOSOL, etc.) and other hydrocarbon solvents, isopropyl myristate (IPM), high-carbon fatty acid esters having 16 to 20 carbon atoms such as hexyl laurate, and other ester solvents, diol ether solvents having 3 to 10 carbon atoms, and ketone solvents. Among them, from the viewpoint of the feeling in use (less stickiness after treatment), lower alcohols having 2 to 3 carbon atoms such as ethanol and isopropyl alcohol (IPA) are preferred, and ethanol is more preferred. The solvent can be used alone or as a mixture of two or more.

[0065] Since the aerosol for controlling pests and tick mites in this embodiment is sprayed in a small amount, it does not pose a major problem for flames. However, a water-based formulation can also be adopted. In this case, the amount of water contained in the aerosol collagen solution is appropriately about 10 to 70 v / v%. In addition, within a range that does not affect the spraying pattern of the spray particles, a small amount of a nonionic surfactant can also be added as a solubilizing aid. Examples of the nonionic surfactant include ethers such as polyoxyethylene alkyl ethers, polyoxyethylene alkyl phenyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, and polyoxyethylene alkyl amino ethers, fatty acid esters such as polyethylene glycol fatty acid esters, polyoxyethylene sorbitan fatty acid esters, and polyoxyethylene glycerol fatty acid esters, polyoxyethylene styrenated phenol, polyalkanolamides of fatty acids, etc. Among them, ethers are particularly preferred.

[0066] (Other components)

[0067] In the aerosol collagen solution, mildew-proof agents, antibacterial agents, fungicides, fragrances, deodorants, stabilizers, antistatic agents, defoamers, excipients, etc. can also be appropriately incorporated. As mildew-proof agents, antibacterial agents, and fungicides, hinokitiol, 2-mercaptobenzothiazole, 2-(4-thiazolyl)benzimidazole, 5-chloro-2-methyl-4-isothiazolin-3-one, thiabendazole, 3-methyl-4-isopropylphenol, o-phenylphenol, etc. can be cited. As fragrances, orange oil, lemon oil, lavender oil, peppermint oil, eucalyptus oil, citronella oil, lime oil, orange oil, jasmine oil, hinoki oil, green tea essential oil, limonene, α-pinene, linalool, geraniol, phenylethyl alcohol, amyl cinnamic aldehyde, p-isopropylbenzaldehyde, benzyl acetate, leaf alcohol and leaf aldehyde known as "green fragrance", etc. can be cited.

[0068] <Propellant>

[0069] As propellants, liquefied petroleum gases (LPG) such as propane, n-butane, and isobutane, liquefied gases such as n-pentane, isopentane, dimethyl ether (DME), and HFO1234ze, and compressed gases such as nitrogen, carbon dioxide, nitrous oxide, and compressed air can be cited. The above propellants can be used alone or in a mixed state, and propellants with LPG as the main component are easy to use. In addition, regarding the propellant, it is preferably used with the gauge pressure (20 °C) adjusted to 0.10 to 0.70 MPa.

[0070] The volume ratio (a / b) of the aerosol collagen solution (a) to the propellant (b) is preferably 10 / 90 to 70 / 30, more preferably 15 / 85 to 60 / 40, further preferably 20 / 80 to 55 / 45, and most preferably 20 / 80 to 50 / 50. By setting the volume ratio (a / b) within the above appropriate range, the control effect against various pests and ticks can be further improved.

[0071] <Composition of aerosol>

[0072] The internal pressure of the aerosol container is not particularly limited, and it is preferably set to 0.60 MPa or less at 25 °C, more preferably 0.15 to 0.60 MPa, further preferably 0.20 to 0.55 MPa, and particularly preferably 0.30 to 0.55 MPa. In the present embodiment, the internal pressure of the aerosol container for controlling pests and ticks can be measured in the following order.

[0073] (1) Immerse the aerosol for controlling pests and ticks in a constant temperature water bath at 25 ± 0.5 °C for 30 minutes.

[0074] (2) Next, place the aerosol for controlling pests and ticks in an upright state, airtightly insert the valve stem of the aerosol container into the insertion port of the pressure gauge, and read the measured pressure to the second decimal place.

[0075] (3) Conduct the above measurement once, without rounding the measured value, and set the value read as the internal pressure value.

[0076] Regarding the aerosol for controlling pests and ticks and mites according to this embodiment, the injection capacity per injection of its metering injection valve can be set to 0.1 to 3.0 mL, preferably set to 0.2 to 1.0 mL, and more preferably set to 0.2 to 0.9 mL. As long as the injection capacity is within the above range, by injecting the aerosol for controlling pests and ticks and mites once to several times, the release amount of the components for controlling pests and ticks and mites will become an appropriate amount of, for example, 0.1 to 50 mg / m 3 or so, which can improve the control effect on various pests and ticks and mites.

[0077] Regarding the aerosol for controlling pests and ticks and mites according to this embodiment, the injection force at 25 °C and a distance of 5 cm from the injection port can be set to 3 to 50 gf (0.029 to 0.49 N), preferably set to 5 to 40 gf (0.049 to 0.39 N), more preferably set to 10 to 35 gf (0.098 to 0.34 N), and particularly preferably set to 12 to 30 gf (0.118 to 0.29 N). As long as the injection force is within the above range, most of the components for controlling pests and ticks and mites will quickly settle and adhere to the ground of the treatment space, which can improve the control effect on various pests and ticks and mites. Such an injection force can be appropriately adjusted by the composition of the aerosol stock solution, the internal pressure of the aerosol container, the shape of the nozzle, etc. In this embodiment, the injection force of the aerosol for controlling pests and ticks and mites can be measured by a digital dynamometer (FGC-0.5, manufactured by Nidec-Shimpo Corporation).

[0078] In the aerosol for controlling pests and ticks and mites according to this embodiment, the shapes of the nozzle, the spray nozzle, the container, etc., and the operation buttons can be appropriately selected. For example, it can be designed as a tabletop type with a button to be pressed from above for injection and a nozzle directed obliquely upward, or it can be designed as a portable type with a small container.

[0079] Regarding the nozzle of the aerosol for controlling pests and ticks and mites according to this embodiment, the number, shape, and size thereof are not particularly limited. For example, the number of nozzles can be one or two or more. From the viewpoint of being able to manufacture simply and at low cost, one nozzle is preferred. In addition, the shape (cross-sectional shape) of the nozzle can be not only circular, elliptical, polygonal, etc., but also irregular. The opening area of the nozzle is preferably 0.05 to 8.0 mm 2 and more preferably 0.1 to 4.0 mm 2 and still more preferably 0.2 to 3.0 mm 2For further optimization. For example, when the number of spray nozzles is one and the shape of the spray nozzle is circular, the size of the spray nozzle (spray nozzle diameter) is preferably 0.3 mm or more, more preferably 0.4 mm or more, and further preferably 0.6 mm or more. In addition, the spray nozzle diameter is preferably 3.0 mm or less, more preferably 2.0 mm or less, and further preferably 1.8 mm or less.

[0080] Regarding the nozzle of the aerosol for pest and tick control of the present embodiment, a nozzle that sprays obliquely upward is preferred. Examples of the container material of the aerosol for pest and tick control of the present embodiment include metals such as aluminum and tinplate, synthetic resins such as polyethylene terephthalate, and pressure-resistant glass. When the container material is a synthetic resin, pressure-resistant glass, etc., it can be semi-transparent or transparent. The shape of the container can be not only a normal cylindrical shape but also a deformed shape. The operation button of the aerosol for pest and tick control of the present embodiment can be a push-type button or a lever-type button.

[0081] Regarding the aerosol for pest and tick control of the present embodiment, by spraying into the air in the treatment space, the release amount of the pest and tick control component into the atmosphere is preferably set to 0.1 - 50 mg / m 3 , more preferably set to 0.5 - 50 mg / m 3 , further preferably set to 1.0 - 40 mg / m 3 , particularly preferably set to 5.0 - 30 mg / m 3 . When the release amount of the pest and tick control component in the atmosphere of the treatment space is 0.1 - 50 mg / m 3 and the aerosol liquid is sprayed, 30% or more of the pest and tick control component by mass will diffuse and adhere to the ground of the treatment space 1 hour after the spraying. Here, the pest and tick control component "diffusing and adhering to the ground of the treatment space" means that as long as the ground can exhibit the pest and tick control effect through the adhering pest and tick control component, the pest and tick control component does not necessarily physically adhere to the ground. By having 30% or more of the pest and tick control component by mass diffuse and adhere to the ground of the treatment space 1 hour after the spraying, the aerosol for pest and tick control of the present embodiment can improve the pest and tick control effect on various pests and ticks. It is natural that the aerosol can quickly exert the pest and tick control effect on various pests and ticks wandering on the ground, and it can also exert the pest and tick control effect on pests and ticks lurking in dark places such as furniture and electrical appliances. According to the volume of the treatment space, the release amount of the pest and tick control component into the atmosphere is 0.1 - 50 mg / m 3By appropriately setting the number of sprays, spray volume, etc., regardless of the volume of the treatment space, the same control effect can be obtained. As the usage frequency of the aerosol for controlling pests and ticks / mites in this embodiment, it is preferably applied at an appropriate time according to the occurrence frequency or situation of pests and ticks / mites so that the release amount of the components for controlling pests and ticks / mites is within the above range.

[0082] (Pests and ticks / mites to be controlled)

[0083] As the pests and ticks / mites that the aerosol for controlling pests and ticks / mites in this embodiment targets, crawling pests can be cited (such as cockroaches like Periplaneta americana, Blattella fuliginosa, Blattella germanica, bed bugs (Cimex lectularius), bed bug species like Cimex hemipterus (tropical bed bug), stink bugs like Halyomorpha halys, ants like Formica japonica, Solenopsis invicta, Lasius japonicus, Monomorium pharaonis, Solenopsis geminata, spiders like Heteropoda venatoria, Steatoda triangulosa, Latrodectus hasselti, millipedes, centipedes like Scolopendra subspinipes, woodlice like Armadillidium vulgare, Porcellio scaber, termites like Coptotermes formosanus, Reticulitermes flaviceps, caterpillars, house mites, hard ticks, fleas), flying pests (such as mosquitoes like Culex pipiens, Aedes albopictus, Aedes aegypti, Culex molestus, flies like Musca domestica, Sarcophaga peregrina, fruit flies, moth flies, midges, bees, moths), fabric pests (such as clothes moths like Tineola bisselliella, Tinea pellionella, beetles like Dermestes maculatus, Anthrenus verbasci), stored-grain pests (such as Sitophilus zeamais), and indoor dust mites (such as Tyrophagus putrescentiae, Acarus siro, Tarsonemus spp., Cheyletus spp., Dermatophagoides americana, Dermatophagoides farinae, Dermatophagoides pteronyssinus). Among them, the aerosol for controlling pests and ticks / mites in this embodiment can particularly achieve a more excellent control effect on ants like Formica japonica, Solenopsis invicta, Lasius japonicus, Monomorium pharaonis, Solenopsis geminata, spiders like Heteropoda venatoria, Steatoda triangulosa, Latrodectus hasselti, cockroaches like Periplaneta americana, Blattella fuliginosa, Blattella germanica, bed bugs (Cimex lectularius), bed bug species like Cimex hemipterus (tropical bed bug), house mites, hard ticks, fleas and other crawling pests, and indoor dust mites like Tyrophagus putrescentiae, Acarus siro, Tarsonemus spp., Cheyletus spp., Dermatophagoides americana, Dermatophagoides farinae, Dermatophagoides pteronyssinus. Especially for the control of indoor dust mites like Tyrophagus putrescentiae, Acarus siro, Tarsonemus spp., Cheyletus spp., Dermatophagoides americana, Dermatophagoides farinae, Dermatophagoides pteronyssinus, the lethal effect is further enhanced.

[0084] [Method for controlling pests and ticks / mites]

[0085] Regarding the method for controlling pests and ticks / mites in this embodiment, it is carried out by using the above aerosol for controlling pests and ticks / mites, and the aerosol for controlling pests and ticks / mites is sprayed into the treatment space for spraying treatment. According to the method for controlling pests and ticks / mites in this embodiment, by using the aerosol for controlling pests and ticks / mites in this embodiment, excellent control effects can be achieved on various pests and ticks / mites.

[0086] The treatment space is preferably an indoor space, but can also be an outdoor space as long as there is little air flow. Additionally, the volume of the treatment space is not particularly limited, and examples include an interstitial space of less than 2.0 m 3 , a narrow space of 2.0 to 18.8 m 3 , a room equivalent to 4.5 to 8 tatami mats with a volume of 18.8 to 33.3 m 3 (area 7.5 to 13.3 m 2 , height 2.2 to 3.0 m) of an indoor space, a room equivalent to 8 to 16 tatami mats with a volume of 33.3 to 66.6 m 3 (area 13.3 to 26.6 m 2 , height 2.2 to 3.0 m) of a slightly larger indoor space, etc. Preferably, it is a narrow space of 2.0 to 18.8 m 3 , a room equivalent to 4.5 to 8 tatami mats with a volume of 18.8 to 33.3 m 3 (area 7.5 to 13.3 m 2 , height 2.2 to 3.0 m) of an indoor space, or a room equivalent to 8 to 16 tatami mats with a volume of 33.3 to 66.6 m 3 (area 13.3 to 26.6 m 2 , height 2.2 to 3.0 m) of a slightly larger indoor space, more preferably a room equivalent to 4.5 to 8 tatami mats with a volume of 18.8 to 33.3 m 3 (area 7.5 to 13.3 m 2 , height 2.2 to 3.0 m) of an indoor space. For example, in a room equivalent to 4.5 to 8 tatami mats with a volume of 18.8 to 33.3 m 3 (area 7.5 to 13.3 m 2 , height 2.2 to 3.0 m) of an indoor space, if the aerosol is sprayed once or multiple times, the release amount of the pest and tick mite control component into the atmosphere will be 0.1 to 50 mg / m 3 . Even in a larger or smaller indoor space, by appropriately setting the spraying frequency, spraying volume, etc. according to the volume of the indoor space, so that the release amount of the pest and tick mite control component into the atmosphere of the indoor space is 0.1 to 50 mg / m 3 , the same pest control effect can be obtained regardless of the volume of the indoor space. As the implementation frequency of the pest and tick mite control method of this embodiment, it is preferably applied at an appropriate time according to the appearance frequency or situation of pests and tick mites so that the release amount of the pest and tick mite control component is within the above range. As indoor spaces, examples include wardrobes, closets, chests of drawers, sideboards, toilets, bathrooms, storage rooms, living rooms, dining rooms, warehouses, inside vehicles, furniture, and gaps between furniture, etc.

[0087] In the method for controlling pests and ticks / mites according to this embodiment, regarding the spraying direction (elevation angle) of the aerosol for controlling pests and ticks / mites, it is preferably obliquely upward, that is, 0 to 60° with respect to the horizontal plane, and more preferably 30 to 60°. In this way, by spraying the aerosol for controlling pests and ticks / mites obliquely upward into the treatment space, the spray particles will spread widely in the air of the treatment space, and the components (A) for controlling pests and ticks / mites contained in the spray particles can settle and adhere to the ground of the treatment space. As a result, excellent control effects can be exerted on various pests and ticks / mites.

[0088] Examples

[0089] The present invention will be further described in detail below by way of examples and comparative examples. However, the present invention is not limited by the examples.

[0090] [Example 1]

[0091] 2.4 g (40 w / v%) of phenothrin as the component (A) for controlling pests and ticks / mites and 0.12 g (2 w / v%) of N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide (a mixture of 30 mol% of Endo type, 70 mol% of Exo type, and Endo / Exo = 30 / 70) as the synergist (B) were dissolved in ethanol as the solvent to prepare an aerosol stock solution. In Table 1, N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide is recorded as "Compound S". 6 mL of the obtained aerosol stock solution and 24 mL of liquefied petroleum gas (LPG) were pressure-filled (product internal pressure: 0.37 MPa / 25 °C) into an aerosol container with a metering spray valve (spray volume per time: 0.4 mL) to obtain the aerosol for controlling pests and ticks / mites of Example 1.

[0092] Regarding Compound S, an isomerization reaction, a condensation reaction, and distillation were carried out according to the manufacturing method disclosed in the above steps (1) to (3) so that the isomer ratio (Endo / Exo) of the Endo type and the Exo type became the values shown in Table 1 for obtaining. In addition, the molar ratio of the Endo type and the molar ratio of the Exo type disclosed in Table 1 were obtained as the ratios (percentages) of the number of moles of the Endo type and the Exo type to the total number of moles of the Endo type and the Exo type, respectively.

[0093] In the aerosol for controlling pests and ticks / mites of Example 1, the total volume (a + b) of the aerosol stock solution (a) and the propellant (b) was 30 mL, and the volume ratio (a / b) of the aerosol stock solution (a) to the propellant (b) was 20 / 80. In addition, the number of spray nozzles was set to one, the spray nozzle shape (cross-sectional shape) was set to circular, and the opening area was set to 0.38 mm2 The nozzle size (nozzle diameter) is set to 0.7 mm. For this aerosol for pest and tick control, the spraying force at 25°C and a distance of 5 cm from the spray nozzle is 14 gf (0.14 N), and the release amount of the pest and tick control components into the atmosphere is 7.68 mg / m 3 .

[0094] [Examples 2 - 15, Comparative Examples 1 - 4]

[0095] Aerosols for pest and tick control of Examples 2 - 15 and aerosols of Comparative Examples 1 - 4 were prepared in the order of Example 1 and according to the formulations shown in Table 1. Regarding compound S, isomerization reaction, condensation reaction, and distillation were carried out according to the manufacturing method disclosed in the above steps (1) - (3) to make the isomer ratio of Endo type to Exo type (Endo / Exo) be the value shown in Table 1. In Table 1, "PBO" represents piperonyl butoxide, "IPA" represents isopropyl alcohol, "IPM" represents isopropyl myristate. Additionally, "Neothiozole" is a normal alkane, and "ISOPAR M" is an isoparaffin.

[0096] In the aerosols for pest and tick control of Examples 2 - 15 and the aerosols of Comparative Examples 1 - 4, the total volume (a + b) of the aerosol stock solution (a) and the propellant (b) was set to 30 mL, and the volume ratio (a / b) of the aerosol stock solution (a) to the propellant (b) was set to the value shown in Table 1. Additionally, the same metering spray valve as in Example 1 was used, and the number of nozzles, nozzle shape (cross-sectional shape), opening area, and nozzle size (nozzle diameter) were set in the same manner as in Example 1.

[0097]

[0098] The aerosols for pest and tick control of Examples 1 - 15 and the aerosols of Comparative Examples 1 - 4 were used as the test aerosols, and the confirmation experiments disclosed below were carried out. The experimental results are shown in Table 2.

[0099] (1) Confirmation experiment on the lethal effect on indoor dust mites (Dermatophagoides pteronyssinus, Tyrophagus putrescentiae)

[0100] Eight deep petri dishes with a diameter of 9 cm and a height of 6 cm (4 for Dermatophagoides pteronyssinus and 4 for Tyrophagus putrescentiae) were placed in the four corners of a closed room with a volume of 25 m 3 (an area of 10 m 2 ). Approximately 200 of the established test mites were placed in each deep petri dish. While changing the direction of the test aerosol from the center of the room to the whole room, the nozzle was sprayed obliquely upward 6 times. After being exposed to the aerosol stock solution for 24 hours, the mortality rate of the test mites was obtained.

[0101] (2) Confirmation experiment on the lethal effect against crawling pests (German cockroaches)

[0102] A total of 4 glass plates of 20×20 cm (4 for German cockroaches) were set at the four corners of a sealed room with a volume of 25 m 3 (area 10 m 2 ). A plastic ring with a diameter of about 20 cm was placed on each glass plate, and a predetermined test insect (German cockroach: 5 female adults) was placed in each ring to allow it to wander freely. While changing the direction of the test aerosol from the center of the room to the whole room, the nozzle was sprayed obliquely upward 6 times. After leaving them exposed to the aerosol stock solution for 24 hours, the test insects together with the plastic rings were transferred to another room, fed with feed, and the mortality rate of the test insects was obtained after another 24 hours.

[0103]

[0104] It can be seen that any of the aerosols for controlling pests and ticks and mites in Examples 1 to 15 showed a mortality rate of more than 80% against Dermatophagoides pteronyssinus or Tyrophagus putrescentiae, which are indoor dust mites, and a mortality rate of more than 90% against German cockroaches, which are crawling pests. Among them, it can be seen that the aerosols for controlling pests and ticks and mites in Examples 1, 3 to 7, 11 and 13 to 15, which contain a non-volatile pyrethroid compound as a component for controlling pests and ticks and mites and have an isomer ratio (Endo / Exo) of 30 / 70 to 70 / 30 in a molar ratio of 2 w / v% or more as a synergist, showed particularly excellent lethal effects against Dermatophagoides pteronyssinus and Tyrophagus putrescentiae, which are indoor dust mites, and any of them showed a mortality rate of more than 90%.

[0105] On the other hand, the aerosols of Comparative Examples 1 and 4 without using a synergist showed a high mortality rate of 90% against German cockroaches, which are crawling pests, but the mortality rate against Dermatophagoides pteronyssinus and Tyrophagus putrescentiae, which are indoor dust mites, remained at 30 to 35%. The aerosol of Comparative Example 2 using an aerosol stock solution containing only N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide as a synergist without containing a component for controlling pests and ticks and mites showed almost no lethal effect against any of Dermatophagoides pteronyssinus and Tyrophagus putrescentiae, which are indoor dust mites, and German cockroaches, which are crawling pests.

[0106] It was also shown that an aerosol of Comparative Example 3 in which a pest- and tick-mite controlling ingredient was used in combination with piperonyl butoxide, as compared with the aerosol of Comparative Example 1 in which no synergist was used in combination, had an increased lethality rate of 50 to 60% against Dermatophagoides pteronyssinus and Tyrophagus putrescentiae, which are house dust mites belonging to the group of house dust mites. However, as compared with the aerosols of Examples 1 to 15 for controlling pests and ticks / mites in which N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide was used as a synergist, the lethal effect was insufficient.

[0107] Industrial applicability

[0108] The aerosol for controlling pests and ticks / mites and the method for controlling pests and ticks / mites of the present invention have excellent control effects on various pests and ticks / mites, and thus can be used not only for indoor use but also for a wide range of purposes for the purpose of controlling pests and ticks / mites.

Claims

1. An aerosol for controlling pests and ticks / mites, which is an aerosol for controlling pests and ticks / mites obtained by filling an aerosol stock solution containing (A) a component for controlling pests and ticks / mites and (B) a synergist into an aerosol container equipped with a metering spray valve. Among them, the (B) synergist is N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide.

2. The aerosol for controlling pests and ticks / mites according to claim 1, wherein, the N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide is a mixture of endo-type and exo-type isomers with an endo / exo isomer ratio of 30 / 70 to 70 / 30 in terms of molar ratio.

3. The aerosol for controlling pests and ticks / mites according to claim 1, wherein, The component for controlling pests and ticks contains a poorly volatile pyrethroid compound having a vapor pressure of less than 1×10 -4 mmHg, i.e., 1.33×10 -5 kPa at 30°C.

4. The aerosol for controlling pests and ticks / mites according to claim 3, wherein, the poorly volatile pyrethroid compound contains phenothrin and / or permethrin.

5. The aerosol for controlling pests and ticks / mites according to claim 1, which is configured such that 30% or more of the (A) component for controlling pests and ticks / mites adheres to the ground of the treatment space by mass 1 hour after spraying.

6. The aerosol for controlling pests and ticks / mites according to claim 1, wherein, The release amount of the ingredient for controlling pests and ticks into the atmosphere is set to 0.1 mg / m 3 ~50 mg / m 3 .

7. The aerosol for controlling pests and ticks / mites according to claim 1, wherein, the metering spray valve is set to have a spray volume of 0.1 mL to 3.0 mL per spray.

8. The aerosol for controlling pests and ticks / mites according to claim 1, wherein, the spray force at a spray distance of 5 cm is set to be 0.029 N to 0.49 N at 25°C.

9. The aerosol for controlling pests and ticks / mites according to claim 1, wherein, the volume ratio a / b of the aerosol stock solution (a) to the propellant (b) is set to 15 / 85 to 60 / 40.

10. The aerosol for controlling pests and ticks / mites according to any one of claims 1 to 9, which targets crawling pests and / or indoor dust mites for control.

11. The aerosol for controlling pests and ticks / mites according to claim 10, which kills the crawling pests and / or indoor dust mites.

12. A method for controlling pests and ticks / mites, which is a method for controlling pests and ticks / mites using an aerosol for controlling pests and ticks / mites. This aerosol is obtained by filling an aerosol stock solution containing (A) a component for controlling pests and ticks / mites and (B) a synergist into an aerosol container equipped with a metering spray valve. Among them, the (B) synergist is N-(2-ethylhexyl)-bicyclo[2,2,1]-hept-5-ene-2,3-dicarboximide, in this method, the aerosol for controlling pests and ticks / mites is sprayed into the treatment space.

13. The method for controlling pests and ticks / mites according to claim 12, which sprays the aerosol for controlling pests and ticks / mites obliquely upward into the treatment space.

Images