Prescription for increasing blood platelets by taking tortoise-plastron glue as monarch drug and application

Abstract

The invention provides a prescription for increasing blood platelets by taking tortoise-plastron glue as a monarch drug and application, and relates to the field of drug preparation. The medicine composition is prepared from the following traditional Chinese medicine decoction pieces by weight: 3g to 36g of radix paeoniae alba, 3g to 36g of fried rhizoma atractylodis macrocephalae, 6g to 50g of fried endothelium corneum gigeriae galli, 3g to 36g of radix salviae miltiorrhizae, 3g to 15g of American ginseng, 3g to 36g of plantain herb, 3g to 36g of circium japonicum, 3g to 30g of tortoise glue, 3g to 25g of honey-fried polygala tenuifolia, 3g to 25g of radix bupleuri and 3g to 60g of mulberry seeds. By treating tooth bleeding, epistaxis and systemic purpura caused by reduction of leukocyte value, erythrocyte value, hemoglobin value and platelet value due to chemotherapy or other reasons of aplastic anemia myelodysplastic syndrome, the traditional Chinese medicine composition has the effects of treating leukocyte, erythrocyte and hemoglobin, removing heat to cool blood, stopping bleeding, enriching blood and generating blood. Moreover, the side effects of chemotherapy can be relieved. The traditional Chinese medicine has safe and stable curative effects, and has the functions of protecting spleen and stomach, protecting liver and kidney, inducing diuresis to reduce edema, filling bone marrow asthenia, soothing nerves

Description

Technical Field

[0001] The present invention relates to the technical field of drug preparation, and specifically relates to a prescription for increasing platelets with tortoise glue as the monarch drug and its application. Background Art

[0002] Aplastic anemia is a hematopoietic system with low function. Normal values: (normal value of white blood cells 4 - 10 - 10^9 / L); (normal value of red blood cells 4 - 5.5 - 10^9 / L); (normal value of hemoglobin 120 - 160 - g / L); (normal value of platelets 100 - 300 - 10^9 / L). (absolute value of neutrophils 1.8 - 8.89 - 10^9 / L) lower than the normal absolute value of 1.8 or below indicates osteoporosis and belongs to myelodysplastic syndrome.

[0003] When the white blood cell count is lower than the normal value, the patient is prone to colds, etc. When it is lower than 2.5 of the normal value, the patient has severe fatigue throughout the body or some patients have swollen lymph nodes and the condition is critical; when the red blood cell count is lower than the normal value, the patient has a pale face and is taciturn; when the hemoglobin is lower than 90 of the normal value, the patient has severe anemia and urgently needs to consider transfusing whole human blood; when the platelet count is lower than 100 - 50, it belongs to low - risk platelets; when the platelet count is lower than 50 - 30, it belongs to medium - risk platelets; when the platelet count is lower than 25 of the normal value, it belongs to high - risk platelets. The patient needs to stay in bed and only by transfusing platelet plasma can life be maintained. However, platelet cells have a metabolic consumption period of about 7 days. Platelet plasma requires blood type matching and is not easily obtained. Transfusing plasma multiple times will produce dependence, which is not the fundamental solution to platelet deficiency. The main way to solve platelet deficiency is for the body to exert its own hematopoietic function, which is the only treatment method. Currently, there is no good treatment method in traditional Chinese medicine clinics. Clinically, western medicine mainly uses hormone drugs: stanozolol, eltrombopag, testosterone undecanoate. Long - term oral administration of stanozolol, testosterone undecanoate, and eltrombopag has the risk of causing lower limb edema and genital carcinogenesis, and has mild damage to the liver and kidneys or systemic pruritus. Long - term oral administration of immunosuppressants, cyclosporine, thalidomide, also causes greater damage to the liver and kidneys, proteinuria, elevated creatinine, elevated alanine aminotransferase, drug - induced uremia, or cirrhosis or jaundice. Nausea, vomiting, abdominal distension, or dry stools and other symptoms. The main treatment method of western medicine is mainly transfusing plasma, which is the only treatment method. Currently, it is a disease that cannot be cured except by bone marrow transplantation. Currently, a prescription for increasing platelets with tortoise glue as the monarch drug is used to treat aplastic anemia, myelodysplastic syndrome, and diseases caused by chemotherapy - induced reduction of white blood cells, red blood cells, hemoglobin, and platelets, with the least pain for patients, stable curative effect, and the least side effects. Summary of the Invention

[0004] (1) Technical Problems to be Solved

[0005] In view of the deficiencies of the prior art, the present invention provides a prescription for increasing platelets with tortoise glue as the monarch drug and its application, which solves the problems that platelet plasma requires blood type matching, is hard to come by, and dependence will be produced after multiple transfusions of plasma.

[0006] (II) Technical Solution

[0007] To achieve the above objectives, the present invention is realized through the following technical solutions: A prescription for increasing platelets with tortoise glue as the monarch drug, and this pharmaceutical composition is prepared from the following traditional Chinese medicine decoction pieces according to the weight in grams: white peony root 3g - 36g, stir-fried atractylodes macrocephala 3g - 36g, stir-fried chicken gizzard membrane 6g - 50g, salvia miltiorrhiza 3g - 36g, American ginseng 3g - 15g, plantain herb 3g - 36g, thistle 3g - 36g, tortoise glue 3g - 30g, honey-fried polygala tenuifolia 3g - 25g, bupleurum chinense 3g - 25g, and mulberry seeds 3g - 60g.

[0008] Preferably, this pharmaceutical composition is prepared from the following traditional Chinese medicine decoction pieces according to the weight in grams: white peony root 3g, stir-fried atractylodes macrocephala 3g, stir-fried chicken gizzard membrane 50g, salvia miltiorrhiza 3g, American ginseng 3g, plantain herb 3g, thistle 3g, tortoise glue 3g, honey-fried polygala tenuifolia 3g, bupleurum chinense 3g, and mulberry seeds 3g.

[0009] Preferably, this pharmaceutical composition is prepared from the following traditional Chinese medicine decoction pieces according to the weight in grams: white peony root 36g, stir-fried atractylodes macrocephala 36g, stir-fried chicken gizzard membrane 6g, salvia miltiorrhiza 36g, American ginseng 15g, plantain herb 36g, thistle 36g, tortoise glue 30g, honey-fried polygala tenuifolia 25g, bupleurum chinense 25g, and mulberry seeds 60g.

[0010] Preferably, the tortoise glue and mulberry seeds: nourish yin and warm the kidney, generate blood and enrich blood, increase platelets and fill the bone marrow; thistle and plantain herb clear heat and cool blood, stop bleeding, and are used for hematuria, dysentery with blood, gingival bleeding, epistaxis, chronic internal bleeding caused by platelet reduction, and systemic edema or purpura caused by anemia.

[0011] Preferably, the stir-fried atractylodes macrocephala and stir-fried chicken gizzard membrane strengthen the spleen and promote digestion: regulate the ascending and descending disorders of the spleen and stomach, and better play the role of the acquired spleen and stomach and the function of controlling blood.

[0012] Preferably, the honey-fried polygala tenuifolia and American ginseng: replenish qi, soothe the nerves and relieve fatigue; salvia miltiorrhiza: a drug guiding to the blood aspect, and the whole prescription is a good prescription for generating blood, enriching blood and increasing platelets, treating both the symptoms and the root causes.

[0013] A prescription for increasing platelets with tortoise glue as the monarch drug, and the preparation method includes the following specific preparation steps:

[0014] Step 1: Remove the moisture or ash content from the traditional Chinese medicine decoction pieces of white peony root, stir-fried atractylodes macrocephala, stir-fried chicken gizzard membrane, salvia miltiorrhiza, American ginseng, plantain herb, thistle, tortoise glue, honey-fried polygala tenuifolia, bupleurum chinense, and mulberry seeds.

[0015] Step 2: Sieve impurities or ash with a 60-mesh sieve.

[0016] Step 3: Drying: The air-dried drugs are all dried to remove moisture. The drying time is 35 - 50 min, and the temperature is 60 - 75 °C.

[0017] Step 4: Grinding: The dried drugs are all ground for 15 min and screened through a 100-mesh sieve. The screened drugs are ground again until the powder size is uniform.

[0018] Step 5: Mixing and granulation: The ground medicinal powder needs to be uniformly mixed with excipients and granulation operation is carried out again to complete the preparation of the drug.

[0019] It is applied in a prescription drug combination for increasing platelet count with tortoise glue as the monarch drug.

[0020] (III) Beneficial effects

[0021] The present invention provides a prescription and its application for increasing platelet count with tortoise glue as the monarch drug, having the following beneficial effects:

[0022] The present invention treats leukocyte count, red blood cell count, hemoglobin value, and platelet count reduction caused by aplastic anemia, myelodysplastic syndrome, chemotherapy or other reasons, resulting in tooth bleeding, nosebleed, and systemic purpura. It has the effects of treating leukocytes, red blood cells, hemoglobin, clearing heat and cooling blood, stopping bleeding, nourishing blood and generating blood, increasing platelet count, promoting diuresis and reducing swelling, and can reduce the side effects of chemotherapy. There are no side effects when taken together with western medicine during the serious illness period. After taking the prescription for increasing platelet count with tortoise glue as the monarch drug for 2 weeks, the dosage of western medicine can be halved. The curative effect is safe and stable, and it has the functions of protecting the spleen and stomach, protecting the liver and kidneys, promoting diuresis and reducing swelling, filling the marrow deficiency, calming the nerves and anti-fatigue. Specific embodiments

[0023] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0024] The raw materials used in this technical solution are all "processed and prepared drugs" stipulated by the Drug Administration Law, called "Chinese herbal pieces". So-called Chinese herbal medicines, raw materials, and crude drugs cannot be directly used clinically. In this article, all are described in terms of (Chinese herbal pieces).

[0025] Example 1:

[0026] An embodiment of the present invention provides a prescription for increasing platelet count with tortoise glue as the monarch drug. The pharmaceutical composition is prepared from the following traditional Chinese medicine pieces in the indicated weight grams: white peony root 3g - 36g, stir-fried atractylodes macrocephala 3g - 36g, stir-fried gallus gallus domesticus gigerii endothelium corneum 6g - 50g, salvia miltiorrhiza 3g - 36g, american ginseng 3g - 15g, plantain herb 3g - 36g, thistle 3g - 36g, tortoise glue 3g - 30g, honey-fried polygala tenuifolia 3g - 25g, bupleurum chinense 3g - 25g, and mulberry seeds 3g - 60g.

[0027] The pharmaceutical composition is prepared from the following traditional Chinese medicine pieces in the indicated weight grams: white peony root 3g, stir-fried atractylodes macrocephala 3g, stir-fried gallus gallus domesticus gigerii endothelium corneum 50g, salvia miltiorrhiza 3g, american ginseng 3g, plantain herb 3g, thistle 3g, tortoise glue 3g, honey-fried polygala tenuifolia 3g, bupleurum chinense 3g, and mulberry seeds 3g.

[0028] Tortoise glue and mulberry seeds: nourish yin and warm the kidneys, generate blood and enrich blood, increase platelet count, and fill the bone marrow; thistle and plantain herb clear heat and cool blood: stop bleeding, used for hematuria, dysentery with blood, gingival bleeding, epistaxis, internal bleeding caused by thrombocytopenia, general edema or purpura caused by anemia; atractylodes macrocephala and gallus gallus domesticus gigerii endothelium corneum strengthen the spleen and promote digestion: regulate the ascending and descending disorders of the spleen and stomach, and better play the role of the acquired spleen and stomach and the function of controlling blood; polygala tenuifolia and american ginseng: replenish qi, soothe the nerves, and resist fatigue; salvia miltiorrhiza: a drug guiding to the blood aspect. The whole prescription is a good prescription for generating blood, enriching blood, and increasing platelet count, treating both the symptoms and the root causes.

[0029] A prescription for increasing platelet count with tortoise glue as the monarch drug, the preparation method includes the following specific preparation steps:

[0030] Step 1: Remove moisture or ash from the traditional Chinese medicine pieces of white peony root, stir-fried atractylodes macrocephala, stir-fried gallus gallus domesticus gigerii endothelium corneum, salvia miltiorrhiza, american ginseng, plantain herb, thistle, tortoise glue, honey-fried polygala tenuifolia, bupleurum chinense, and mulberry seeds.

[0031] Step 2: Sieve out impurities or ash with a 60-mesh sieve.

[0032] Step 3: Drying: The air-dried drugs are all dried to remove moisture. The drying time is 35 - 50 min, and the temperature is 60 - 75 °C.

[0033] Step 4: Grinding: The dried drugs are all ground for 15 min and screened through a 100-mesh sieve. The screened drugs are ground again until the powder size is uniform.

[0034] Step 5: Mixing and granulation: The ground medicinal powder needs to be evenly mixed with excipients, and granulation operation is carried out again to complete the preparation of the drug.

[0035] It is applied in a prescription drug combination for increasing platelet count with tortoise glue as the monarch drug.

[0036] Example two:

[0037] The difference between this embodiment and the first embodiment lies in: a prescription for increasing platelets with tortoise glue as the monarch drug. The pharmaceutical composition is prepared from the following traditional Chinese medicine pieces according to the weight in grams: white peony root 36g, stir-fried atractylodes macrocephala 36g, stir-fried chicken inner gold 6g, salvia miltiorrhiza 36g, American ginseng 15g, plantain herb 36g, thistle 36g, tortoise glue 30g, honey-fried polygala tenuifolia 25g, bupleurum 25g, and mulberry seeds 60g.

[0038] Tortoise glue and mulberry seeds: nourish yin and warm the kidney, generate blood and enrich blood, increase platelets and fill the bone marrow; thistle and plantain herb clear heat and cool blood: stop bleeding, used for hematuria, dysentery with blood, gingival bleeding, nosebleed, internal bleeding caused by thrombocytopenia, general edema or purpura caused by anemia; stir-fried atractylodes macrocephala and stir-fried chicken inner gold strengthen the spleen and promote digestion: regulate the ascending and descending disorders of the spleen and stomach, and better play the role of the acquired spleen and stomach and the function of controlling blood; honey-fried polygala tenuifolia and American ginseng: replenish qi, soothe the nerves and relieve fatigue; salvia miltiorrhiza: a drug guiding to the blood aspect. The whole prescription is a good prescription for generating blood, enriching blood and increasing platelets, treating both the symptoms and the root causes.

[0039] A preparation method of a prescription for increasing platelets with tortoise glue as the monarch drug, including the following specific preparation steps:

[0040] Step 1: Remove moisture or ash from the traditional Chinese medicine pieces of white peony root, stir-fried atractylodes macrocephala, stir-fried chicken inner gold, salvia miltiorrhiza, American ginseng, plantain herb, thistle, tortoise glue, honey-fried polygala tenuifolia, bupleurum, and mulberry seeds.

[0041] Step 2: Sieve out impurities or ash with a 60-mesh sieve.

[0042] Step 3: Drying: The air-dried drugs are all dried to remove moisture. The drying time is 35 - 50 minutes, and the temperature is 60 - 75 °C.

[0043] Step 4: Grinding: The dried drugs are all ground for 15 minutes and screened through a 100-mesh sieve. The screened drugs are ground again until the powder size is uniform.

[0044] Step 5: Mixing and granulation: The ground medicinal powder needs to be uniformly mixed with excipients, and granulation operation is carried out again to complete the preparation of the drug.

[0045] Example 3:

[0046] The difference between this embodiment and the first embodiment lies in: The pharmaceutical composition is prepared from the following traditional Chinese medicine pieces according to the weight in grams: white peony root 20g, stir-fried atractylodes macrocephala 20g, stir-fried chicken inner gold 30g, salvia miltiorrhiza 20g, American ginseng 10g, plantain herb 20g, thistle 20g, tortoise glue 15g, honey-fried polygala tenuifolia 10g, bupleurum 15g, and mulberry seeds 40g.

[0047] Tortoise glue and mulberry seeds: nourishing yin and warming the kidneys, generating blood and enriching blood, increasing platelets and filling the bone marrow; Cirsium japonicum and Plantago asiatica clear heat and cool blood: stop bleeding, used for hematuria, dysentery with blood, gum bleeding, nosebleed, internal bleeding caused by thrombocytopenia, and general edema or purpura caused by anemia; stir-fried Atractylodes macrocephala and stir-fried Endothelium corneum gigeriae galli strengthen the spleen and promote digestion: regulate the dysfunction of the spleen and stomach in ascending and descending, and better play the role of the acquired spleen and stomach and the function of controlling blood; honey-roasted Polygala tenuifolia and American ginseng: replenish qi, soothe the nerves and resist fatigue; Salvia miltiorrhiza: a drug guiding to the blood aspect. The whole prescription is a good prescription for generating blood, enriching blood and increasing platelets, treating both the symptoms and the root causes.

[0048] A prescription for increasing platelets with tortoise glue as the monarch drug, and the preparation method includes the following specific preparation steps:

[0049] Step 1: Remove moisture or ash from the Chinese herbal medicine pieces of Paeonia lactiflora, stir-fried Atractylodes macrocephala, stir-fried Endothelium corneum gigeriae galli, Salvia miltiorrhiza, American ginseng, Plantago asiatica, Cirsium japonicum, tortoise glue, honey-roasted Polygala tenuifolia, Bupleurum chinense and mulberry seeds.

[0050] Step 2: Sieve out impurities or ash with a 60-mesh sieve.

[0051] Step 3: Drying: The air-dried drugs are all dried to remove moisture. The drying time is 35 - 50 minutes, and the temperature is 60 - 75 °C.

[0052] Step 4: Grinding: The dried drugs are all ground for 15 minutes and screened through a 100-mesh sieve. The screened drugs are ground again until the powder size is uniform.

[0053] Step 5: Mixing and granulation: The ground medicinal powder needs to be evenly mixed with excipients, and granulation operation is carried out again to complete the preparation of the drug.

[0054] Example 4:

[0055] The difference between this example and Example 1 lies in: functions and indications: nourishing yin and strengthening the kidneys, filling the bone marrow, generating and enriching blood, clearing heat and cooling blood, stopping bleeding, used for the treatment of aplastic anemia, myelodysplastic syndrome, and other chemotherapy-induced low values of white blood cells, red blood cells, hemoglobin, and platelet counts, presenting headache, dizziness, general fatigue, tooth bleeding, nosebleed, increasing platelets, general purpura or chronic internal bleeding, as well as general edema.

[0056] Dosage and administration: The dosage of the prescription is adjusted temporarily according to age and physical strength. Decoct 800 ml of water for 15 minutes for each dose, then put Cirsium japonicum and Plantago asiatica into the pot and decoct for another 5 minutes, and take it orally in three times. It can also be crushed into powder or made into granules. For adults, take 6 grams each time, three times a day; for children, take 3 grams each time, three times a day. Soak it with 100 °C boiling water for 5 minutes and take it orally.

[0057] When the absolute value of neutrophil is lower than 1.8 of the normal value, taking the prescription for increasing platelets with tortoise glue as the monarch drug orally and taking cod liver oil orally at the same time has better curative effect.

[0058] (Adverse reactions) are not yet clear.

[0059] (Contraindications): ① Use with caution or avoid use if the platelet count is below 30. Avoid use if the platelet count is above 350, or seek medical attention.

[0060] (Precautions): ① This medicine should be stored away from high temperatures and should not be exposed to direct sunlight.

[0061] ② During the illness, avoid consuming: ginger, garlic, scallions, alcohol, spicy foods, fishy foods, and foods with a pungent aroma, as these can accelerate platelet depletion.

[0062] Example 5:

[0063] ① For example 1, Guo XX, male, 67 years old, suffering from aplastic anemia and myelodysplastic syndrome, with a white blood cell count below 2.5, a red blood cell count of 2.8, a hemoglobin level below 90, and a platelet count of 18. He often received plasma or whole blood transfusions. In a situation where there was no effective treatment, he received a platelet-increasing formula with tortoise glue as the monarch drug, one dose per day, decocted in 800 ml of water and taken in three divided doses. At the same time, he took 30 ml of milk-white cod liver oil orally, divided into two doses, with better efficacy. The patient was of advanced age and survived for more than 5 years.

[0064] ② For example 2, Huang XX, female, 47 years old, who had a hysterectomy due to uterine cancer. During chemotherapy, she experienced hair loss, pale complexion, dizziness, headache, and general fatigue. Her white blood cell count was 2.5, hemoglobin level was 90, red blood cell count was 3.0, and platelet count was 28. During chemotherapy, she took a platelet-increasing formula with tortoise glue as the monarch drug orally for nearly a year without receiving plasma transfusions, and overcame the side effects of chemotherapy. Now she has recovered.

[0065] ③ For example 3, Shuai XX, female, 49 years old, with advanced uterine cancer that could not be resected. She underwent chemotherapy for more than two years. Finally, due to metastasis of cancer to the lungs and liver in the advanced stage, while taking the formula with tortoise glue as the monarch drug, one dose per day, decocted in water and taken in three divided doses, the patient felt that the side effects brought by chemotherapy were significantly reduced over the two-year period.

[0066] ④Example 4: Huang XX, male, has suffered from aplastic anemia for many years. Western medicine treatment uses hormones and inhibitors, resulting in elevated urine protein, elevated creatinine, and elevated alanine aminotransferase. The drug-induced damage has caused the kidneys to shrink. There are abnormal liver function, abnormal electrocardiogram, sinus rhythm, and inferior wall myocardial infarction with an unknown timing. There are also hypertension and multiple chronic diseases. He orally took a prescription with tortoise glue as the monarch drug to increase platelets. On August 9, 2024, the white blood cell count was 3.29, the red blood cell count was 2.83, the hemoglobin was 99, and the platelet count was 31. One month later, on September 9, 2024, the white blood cell count was 3.48, the red blood cell count was 3.10, the hemoglobin was 109, and the platelet count was 43. All western medicine hormone drugs and inhibitor drugs were stopped, and he continued to orally take the prescription with tortoise glue as the monarch drug to increase platelets. During the physical examination for the elderly on April 11, 2025, (white blood cell count 4.18, normal), (red blood cell count 3.31); (hemoglobin 120, normal); (platelet count 61, slightly critical). Western medicine treatment, except for plasma transfusion and bone marrow transplantation, does not have such a treatment effect.

[0067] Huang XX's platelet count often dropped below 20, and he received multiple plasma transfusions. So far, he has orally taken the prescription with tortoise glue as the monarch drug to increase platelets for more than seven months. The platelet count has increased from 31 to 61 on April 11, belonging to slightly critical aplastic anemia platelets. The treatment effect is obvious. Moreover, two weeks after orally taking the prescription with tortoise glue as the monarch drug to increase platelets, the western medicine dosage was halved, and one month later, all western medicine was stopped. He orally took the prescription with tortoise glue as the monarch drug made into powder granules, 3 times a day, 6 grams each time, brewed with boiling water for 5 minutes and taken. The curative effect is safe and stable. He dances square dance every day and walks 10,000 steps, and survives well while being ill.

[0068] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A prescription for increasing platelet count with tortoise glue as the monarch drug, characterized in that: The pharmaceutical composition is prepared from the following traditional Chinese medicine pieces according to the weight in grams: white peony root 3g - 36g, stir-fried atractylodes macrocephala 3g - 36g, stir-fried chicken gizzard-membrane 6g - 50g, salvia miltiorrhiza 3g - 36g, American ginseng 3g - 15g, plantain herb 3g - 36g, thistle 3g - 36g, tortoise glue 3g - 30g, roasted polygala tenuifolia 3g - 25g, bupleurum chinense 3g - 25g, and mulberry seeds 3g - 60g.

2. A prescription for increasing platelet count with tortoise glue as the monarch drug according to claim 1, characterized in that: The pharmaceutical composition is prepared from the following traditional Chinese medicine pieces according to the weight in grams: white peony root 3g, stir-fried atractylodes macrocephala 3g, stir-fried chicken gizzard-membrane 50g, salvia miltiorrhiza 3g, American ginseng 3g, plantain herb 3g, thistle 3g, tortoise glue 3g, honey-roasted polygala tenuifolia 3g, bupleurum chinense 3g, and mulberry seeds 3g.

3. A prescription for increasing platelet count with tortoise glue as the monarch drug according to claim 1, characterized in that: The pharmaceutical composition is prepared from the following traditional Chinese medicine pieces according to the weight in grams: white peony root 36g, stir-fried atractylodes macrocephala 36g, stir-fried chicken gizzard-membrane 6g, salvia miltiorrhiza 36g, American ginseng 15g, plantain herb 36g, thistle 36g, tortoise glue 30g, honey-roasted polygala tenuifolia 25g, bupleurum chinense 25g, and mulberry seeds 60g.

4. A prescription for increasing platelet count with turtle glue as the monarch drug according to claim 1, characterized in that: The said tortoise glue and mulberry seeds: nourish yin and warm the kidney, generate blood and enrich blood, increase platelets and fill the bone marrow; thistle and plantain herb clear heat and cool blood, stop bleeding, and are used for hematuria, dysentery with blood, gum bleeding, epistaxis, chronic internal bleeding caused by thrombocytopenia, and systemic edema or purpura caused by anemia.

5. A prescription for increasing platelet count with turtle glue as the monarch drug according to claim 1, characterized in that: The said stir-fried atractylodes macrocephala and stir-fried chicken gizzard-membrane strengthen the spleen and promote digestion: regulate the ascending and descending disorders of the spleen and stomach, and better play the role of the acquired spleen and stomach and the function of controlling blood.

6. A prescription for increasing platelet count with tortoise glue as the monarch drug according to claim 1, characterized in that: The said honey-roasted polygala tenuifolia and American ginseng: replenish qi, soothe the nerves and resist fatigue; Salvia miltiorrhiza: a drug guiding to the blood aspect. The whole prescription is a good prescription for generating blood, enriching blood and increasing platelets, treating both the symptoms and the root causes.

7. A prescription for increasing platelet count with tortoise glue as the monarch drug according to claim 1, characterized in that: It also includes a preparation method of a prescription for increasing platelets with tortoise glue as the monarch drug. The preparation method includes the following specific preparation steps: Step 1: Remove the ash or moisture from the traditional Chinese medicine pieces of white peony root, stir-fried atractylodes macrocephala, stir-fried chicken gizzard-membrane, salvia miltiorrhiza, American ginseng, plantain herb, thistle, tortoise glue, honey-roasted polygala tenuifolia, bupleurum chinense, and mulberry seeds. Step 2: Sieve out impurities or ash with a 60-mesh sieve. Step 3: Drying: The air-dried drugs are all dried to remove moisture. The drying time is 35 - 50 min, and the temperature is 60 - 75 °C. Step 4: Grinding: The dried drugs are all ground for 15 min and screened through a 100-mesh sieve. The screened drugs are ground again until the powder size is uniform. Step 5: Mixing and granulating: The ground drug powder needs to be evenly mixed with excipients, and granulating operation is carried out again to complete the preparation of the drug.

8. Application in a pharmaceutical combination of a prescription for increasing platelets with tortoise glue as the monarch drug according to any one of claims 1 - 7.