Tyrosine purification process

Abstract

The invention discloses a tyrosine purification process, which belongs to the technical field of tyrosine purification, and comprises the following steps: step 1, adding water to dissolve a tyrosine crude product obtained by hydrolyzing and extracting pig blood powder to obtain a crude product full solution; 2, heating the crude product full solution obtained in the step 1 at a constant temperature, stirring at a constant speed, adding activated carbon for adsorption in the process, and filtering while the solution is hot to obtain a filtrate; 3, cooling and filtering the filtrate obtained in the step 2 to obtain crystals; 4, spraying and washing the crystals obtained in the step 3 through absolute ethyl alcohol; 5, drying and taking out; wherein the step one to the step five are implemented through a purification device. The one-stop purification device is adopted to realize automatic purification, the automation degree is high, the operation is convenient, the personnel consumption is small, in addition, the influence of the internal environment of a factory in the purification process can be reduced, and the purification environment guarantee degree is high.

Description

Technical Field

[0001] The present invention belongs to the technical field of tyrosine purification, and particularly relates to a tyrosine purification process. Background Art

[0002] The preparation of L-tyrosine mainly adopts the method of protein hydrolysis extraction. Usually, raw materials such as pig blood powder, hoofs, and silk are used, hydrolyzed by acid, and then separated and purified.

[0003] When using pig blood powder for processing, the following method is adopted for processing:

[0004] Pig blood powder [HCl (hydrolysis)] → [110 °C, 24 h] Hydrolysate [acid removal] → [Evaporation and concentration] Acid removal solution [Activated carbon] → Decolorized solution [Decolorization, cooling crystallization] → Crude L-tyrosine [Activated carbon (refining)] → [90 °C, 30 min] Filtrate [Crystallization] → L-tyrosine.

[0005] Among them, for hydrolysis and acid removal, pig blood powder, water, and industrial hydrochloric acid are respectively put into a hydrolysis tank according to a weight ratio of 1:1.3:1, heated to 112 - 114 °C, stirred and refluxed for 24 h and then stopped, cooled and filtered to remove, and the filtrate obtained is the hydrolysate.

[0006] The hydrolysate is evaporated and concentrated to a syrup state, then dissolved in water and evaporated and concentrated again. This process of acid removal is repeated three times. The decolorized and crystallized concentrated solution is diluted with distilled water until completely dissolved, then ammonia water is added to adjust the pH value of the solution to 3.5, 1% activated carbon is added, stirred and boiled for 10 min, kept warm in a water bath at 90 °C with stirring for 30 min, filtered while it is hot, adsorbed by the activated carbon layer, and washed 3 times with distilled water. The filtrate and the washing liquid are combined. According to this method, continue to decolorize with activated carbon until the solution turns light yellow, and the filtrate is left to stand at 10 °C or below for 24 h, then crystals will precipitate, and the crude L-tyrosine is obtained by filtration.

[0007] Obviously, the obtained crude L-tyrosine is not sufficient for some processing fields with high purity requirements. The main reason is that such crude L-tyrosine contains a certain amount of chloride complexes and some impurity particles, especially when tyrosine is used as a food additive. Therefore, it is necessary to purify the crude L-tyrosine.

[0008] In the existing tyrosine purification operation, usually, the crude L-tyrosine and distilled water are mixed and stirred according to a weight ratio of 1:15 until the crude tyrosine is dissolved in the distilled water. Then the solution is added to a treatment tank, and activated carbon is added according to a ratio of 1:100 by weight to the crude tyrosine for particle adsorption. Finally, the solution is added to a centrifuge filter for filtration, and the obtained filtrate is dried to obtain tyrosine crystals.

[0009] However, there are also some deficiencies in this purification process: during the process from dissolution to crystallization, due to the requirements of the process itself, it needs to be transferred to different equipment for operation. Affected by the internal environment of the factory, the environmental protection degree of this purification process is not high, and the consumption of personnel is large. In addition, the purified tyrosine obtained by static adsorption and static crystallization is affected by the amount of chlorine-containing compounds and impurity particles contained in the crude L-tyrosine itself, thus affecting its purity. Therefore, it is necessary to set up a one-stop dynamic adsorption and dynamic flushing crystallization purification process for crude L-tyrosine to meet the higher purity requirements of tyrosine. Summary of the Invention

[0010] The purpose of the present invention is to provide a tyrosine purification process to solve the problems existing in the prior art.

[0011] To achieve the above purpose, the present invention provides the following technical solution: a tyrosine purification process, including the following steps:

[0012] Step 1: Dissolve the crude tyrosine extracted by hydrolyzing blood meal in water to obtain a crude product full solution;

[0013] Step 2: Keep the crude product full solution obtained in Step 1 at a constant temperature and stir it evenly. During the process, add activated carbon for adsorption, and filter while it is hot to obtain a filtrate;

[0014] Step 3: Cool and filter the filtrate obtained in Step 2 to obtain crystals;

[0015] Step 4: Spray-wash the crystals obtained in Step 3 with absolute ethanol;

[0016] Step 5: Dry and take out;

[0017] Among them, Steps 1 to 5 are all implemented through a purification device. The purification device includes a base. One side of the base is provided with a support column 1, and a cleaning and filtering mechanism is arranged on the support column 1. The cleaning and filtering mechanism is used to load the crude tyrosine, heat and stir the crude tyrosine with water, and adsorb and filter the crude product full solution;

[0018] The other side of the base is provided with a support column 2. The top of the support column 2 is provided with a mounting platform plate. A boosting mechanism is arranged on the top of the mounting platform plate, and a processing frame is installed on the boosting mechanism. An automatic drawing mechanism is installed on the processing frame. A cold filtering mechanism is arranged on one side of the automatic drawing mechanism and the cold filtering mechanism is inserted into the processing frame. The cleaning and filtering mechanism is communicated with the processing frame through a spraying and discharging mechanism; the boosting mechanism is used to increase the fluidity of the filtrate on the cold filtering mechanism; the automatic drawing mechanism is used to drive the cold filtering mechanism to be drawn out and loaded into the processing frame; the spraying and discharging mechanism is used to spray and discharge the full solution obtained from the cleaning and filtering mechanism to the cold filtering mechanism; the cold filtering mechanism is used to cool and crystallize the full solution and filter the remaining liquid in the crystals;

[0019] The treatment box is evenly provided with top bar frames, and heating bars for heating the filtrate on the cold filtration mechanism are arranged in each of the top bar frames;

[0020] A spraying and washing mechanism is arranged on the automatic pulling mechanism, and the spraying and washing mechanism is used to spray and wash the crystals with absolute ethanol; exhaust components are evenly arranged on the top bar frames, and the exhaust components are used to discharge the gas generated by the heating of the heating bars.

[0021] Compared with the prior art, the beneficial effects of the present invention are:

[0022] The tyrosine purification process of the present invention realizes automatic purification through a one-stop purification device, has a high degree of automation, is convenient to operate and consumes less personnel. In addition, it can reduce the influence of the internal environment of the factory during the purification process, and has a high purification environment guarantee;

[0023] Adopting a one-stop closed treatment method, dissolving the crude tyrosine product in water and heating for adsorption, then cooling, filtering and crystallizing, and spraying and washing the tyrosine crystals with absolute ethanol, can effectively dissolve and flow down the surface organic impurities that have not been effectively removed in the front stage of the tyrosine crystals. And due to its low polarity, absolute ethanol usually does not dissolve in the form of tyrosine crystals, thereby improving the crystal purity; and under the subsequent heating, absolute ethanol can quickly volatilize and will not remain on the crystal surface, thus ensuring the purity of the tyrosine crystals. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a front view schematic diagram of the present invention;

[0025] Figure 2 is Figure 1 a partial sectional schematic diagram;

[0026] Figure 3 is Figure 1 a top view schematic diagram;

[0027] Figure 4 is Figure 1 a sectional schematic diagram taken along line A-A of

[0028] Figure 5 is Figure 1 a left view schematic diagram;

[0029] Figure 6 is Figure 2 a magnified structural schematic diagram at position a of

[0030] Figure 7 is Figure 2 a magnified structural schematic diagram at position b of

[0031] Figure 8This is a schematic diagram of the distribution of the cooling plate and the filter strips of the present invention;

[0032] Figure 9 for Figure 2 Enlarged structural diagram of the intercooler conduction mechanism;

[0033] Figure 10 It is a schematic diagram of the distribution of vortex tube coolers in the cooling conduction mechanism of the present invention;

[0034] Figure 11 It is a schematic diagram of the process flow of the present invention;

[0035] Figure 12 It is a schematic diagram of the connection of each module in the development board of the present invention.

[0036] In the figure: 1 base, 2 support column 1, 3 insulation base plate, 4 insulation sleeve frame, 5 loading cylinder, 6 heating ring, 7 insulation plate, 8 motor 1, 9 turntable, 10 side rod, 11 support net, 12 filter plate, 13 stirring plate, 14 loading leakage pipe, 15 pressure plate, 16 connecting rod, 17 cover plate, 18 electric telescopic rod 1, 19 connecting plate, 20 support pipe, 21 booster water pump, 22 solenoid valve 1, 23 row pipe, 24 sealing plate, 25 plane thrust roller bearing, 26 soft sealing ring, 27 side sealing ring;

[0037] 28 Support column 2, 29 Mounting table, 30 Mounting table frame, 31 Soft board, 32 Support column, 33 Support board, 34 Processing frame, 35 Vibrator, 36 Soft pipe, 37 Support plate, 38 Electric telescopic rod 2, 39 Cover plate, 40 Pressure sealing ring, 41 Support frame, 42 Cooling frame, 43 Filter strip, 44 Cooling plate, 45 Mobile frame, 46 Nozzle, 47 Middle pipe, 48 Connecting pipe, 49 Booster pump 1, 50 Suction hose, 5 1 mounting plate, 52 motor 2, 53 rotating shaft, 54 driving wheel, 55 row pipe, 56 insulation sleeve, 57 branch row pipe, 58 solenoid valve 2, 59 discharge pipe, 60 booster pump 2, 61 through pipe, 62 row through pipe, 63 inner row pipe, 64 row dripper, 65 ethanol gas sensor, 66 exhaust pipe, 67 solenoid valve 2, 68 side air pipe, 69 exhaust pipe, 70 pressure-sensitive exhaust pump, 71 top bar frame, 72 heating bar;

[0038] 73 support column three, 74 control box, 75 development board, 76 integrated relay, 77 driver, 78 industrial computer, 201 discharge hose, 204 liquid level sensor, 401 insulation strip, 402 cooling pipe, 403 intermediate cooling strip, 404 vortex tube cooler. DETAILED DESCRIPTION

[0039] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the accompanying drawings in the embodiments of the present invention.

[0040] See also Figure 1 ,Figure 2 , Figure 3 , Figure 5 and Figure 11 , a tyrosine purification process, comprising the following steps:

[0041] Step 1: Dissolve the crude tyrosine obtained by hydrolyzing pig blood powder in water to obtain a crude product full solution. The volume ratio of the crude tyrosine used once to distilled water is 1:20.

[0042] Dissolve the crude tyrosine in distilled water in a fully dissolved manner to provide conditions for subsequent centrifugal screening and addition of activated carbon for adsorption.

[0043] Step 2: Carry out constant temperature heating and uniform stirring on the crude product full solution obtained in Step 1, add activated carbon for adsorption during the process, and filter while it is hot to obtain a filtrate; the stirring speed is 150 r / min, the constant temperature heating temperature is 80°C - 90°C, the stirring time is 60 min; the weight ratio of activated carbon to crude tyrosine is 1:100.

[0044] Through the method of constant temperature heating, the crude tyrosine is more refined and effectively dissolved in distilled water, and the tyrosine molecules are effectively separated from particulate impurities and chlorides. Thus, with the cooperation of the stirring operation, the particulate impurities and chlorides are more evenly distributed in each area, which is more conducive to effectively screening out the particulate impurities and chlorides, while tyrosine and water are screened out;

[0045] During the stirring process, the fluidity of the liquid is increased, so that when the activated carbon exerts its particulate adsorption characteristics, it can more effectively capture the impurity particles in the solution.

[0046] Step 3: Cool and filter the filtrate obtained in Step 2 to obtain crystals;

[0047] The purpose of cooling is to accelerate the filtrate to form a supersaturated state, promote the precipitation of tyrosine crystals, thereby improving production efficiency, and by using the cooling method, tyrosine is easily crystallized on the plate surface, thus providing conditions for effective spraying and washing with anhydrous ethanol.

[0048] Step 4: Spray and wash the crystals obtained in Step 3 with anhydrous ethanol; the number of times of spraying anhydrous ethanol is two.

[0049] By spraying and washing with anhydrous ethanol, the organic impurities on the surface of the tyrosine crystals can be effectively dissolved quickly, and anhydrous ethanol usually does not dissolve tyrosine in crystal form due to its low polarity, thereby improving the crystal purity; and after subsequent heating, anhydrous ethanol can quickly volatilize and will not remain on the crystal surface, thus ensuring the purity of the crystal.

[0050] Step 5: Dry and take out, the drying temperature is 60°C.

[0051] Among them, steps one to five are all implemented through a purification device. The purification device includes a base 1. On the left side of the base 1, support columns 1 are symmetrically bolt-fixed. A cleaning and filtering mechanism is installed on the support columns 1. The cleaning and filtering mechanism is used to load the crude tyrosine product, heat and stir the crude tyrosine product with water, and adsorb and filter the whole crude product solution.

[0052] On the right side of the base 1, a support column 28 is bolt-fixed. On the top of the support column 28, a mounting plate 29 is bolt-fixed. A boosting mechanism is installed on the top of the mounting plate 29, and a processing frame 34 is installed on the boosting mechanism. An automatic drawing mechanism is installed on the processing frame 34. A cold filtering mechanism is arranged on one side of the automatic drawing mechanism, and the cold filtering mechanism is inserted into the processing frame 34. The cleaning and filtering mechanism is communicated with the processing frame 34 through a spraying and discharging mechanism. The boosting mechanism is used to increase the fluidity of the filtrate on the cold filtering mechanism. The automatic drawing mechanism is used to drive the cold filtering mechanism to be drawn out and loaded into the processing frame 34. The spraying and discharging mechanism is used to spray and discharge the whole solution obtained from the cleaning and filtering mechanism to the cold filtering mechanism. The cold filtering mechanism is used to cool and crystallize the whole solution and filter the remaining liquid in the crystal.

[0053] On the processing frame 34, top strip frames 71 are uniformly arranged, and heating strips 72 for heating the filtrate on the cold filtering mechanism are arranged in the top strip frames 71.

[0054] A spraying and washing mechanism is arranged on the automatic drawing mechanism. The spraying and washing mechanism is used to spray and wash the crystal with absolute ethanol. Exhaust components are uniformly arranged on the top strip frames 71. The exhaust components are used to discharge the gas generated by heating the heating strips 72.

[0055] Refer to Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 、 Figure 5 and Figure 6 The cleaning and filtering mechanism includes a heat-insulating base plate 3 bolt-fixed on the top of the support column 1. A heat-insulating sleeve frame 4 is bolt-fixed on the top of the heat-insulating base plate 3. The heat-insulating base plate 3 and the heat-insulating sleeve frame 4 are made of heat-insulating concrete. A loading cylinder 5 is embedded and fixed in the heat-insulating sleeve frame 4. A heating ring 6 is bolt-fixed at the bottom of the loading cylinder 5. The heating ring 6 is an electromagnetic heating plate. An insulating plate 7 is bolt-fixed at the center position of the bottom of the loading cylinder 5. The insulating plate 7 is a muscovite plate. A motor 1 8 is bolt-fixed at the bottom of the insulating plate 7. The rotor shaft of the motor 1 8 penetrates through the insulating plate 7 and is connected with a rotating disc 9. The loading cylinder 5 is made of stainless steel. A bearing groove is arranged at the center position of the bottom of the loading cylinder 5. A sealed bearing is inserted into the bearing groove in an interference fit and sealed manner. The inner ring of the sealed bearing is inserted into the rotor shaft of the motor 1 8 in an interference fit and sealed manner.

[0056] The outer edge of the rotating disk 9 is circumferentially bolted to the side rod 10. A support net 11 is welded between adjacent side rods 10. The mesh diameter of the support net 11 is 1 mm. A filter plate 12 is bolted to the support net 11. The filter plate 12 is formed by overlapping three filter meshes with a mesh number of 3250 in a staggered manner. A stirring plate 13 is welded to the inner side of the side rod 10;

[0057] When the motor one 8 rotates, the rotation of the stirring plate 13 drives the filtrate to rotate at high speed inside the support net 11, so that the distilled water carrying tyrosine molecules in the whole solution is thrown out at high speed through the mesh holes of the filter plate 12, while the particulate impurities and chloride complexes are screened and retained between the mesh cylinders formed by the support net 11.

[0058] At the central position of the upper end of the rotating disk 9, a loading leak pipe 14 is flange-connected. The loading leak pipe 14 is used to load activated carbon particles. A pressing plate 15 is slidably inserted into the loading leak pipe 14 and the pressing plate 15 presses on the activated carbon particles;

[0059] The activated carbon particles are made of bamboo charcoal, with a particle diameter of 3 mm. The mesh diameter of the loading leak pipe 14 is 1 mm. The pressing plate 15 is made of stainless steel.

[0060] Under the high-speed rotation of the rotating disk 9, the stirring plate 13 drives the solution between the mesh cylinders formed by the support net 11 to be in a swirling and throwing state, so that a more effective outward centrifugal motion is formed for the solution between the mesh cylinders formed by the support net 11; in this process, when the solution is centrifugally blended, the activated carbon particles will adsorb the particulate impurities contained in it.

[0061] At the rear side of the heat preservation base plate 3, an electric telescopic rod one 18 is bolted. The electric telescopic rod one 18 is a stepping motor-driven electric telescopic rod. The top rod of the electric telescopic rod one 18 is bolted to a connecting plate 19 and the front side of the connecting plate 19 is bolted to a support pipe 20. The top port of the support pipe 20 is flange-connected to the discharge pipe of a booster water pump 21. The suction pipe of the booster water pump 21 is connected to a discharge hose 201, and the discharge hose 201 is inserted into an external distilled water tank; the lower port of the support pipe 20 is flange-connected to the inlet end of a solenoid valve one 22, and the discharge end of the solenoid valve one 22 is flange-connected to a discharge pipe 23. The lower end of the discharge pipe 23 is integrally provided with a sealing plate 24;

[0062] An outer bearing groove is provided at the bottom outer edge of the sealing plate 24. A flat thrust roller bearing 25 is press-fitted into the bearing groove. The lower bearing surface of the flat thrust roller bearing 25 is flush with the lower port of the bearing groove, and the outer edge of the lower bearing surface is in sliding contact with the inner wall of the bearing groove; the top parts of the side rod 10, the support net 11 and the filter plate 12 are welded with a soft sealing plate 26. The soft sealing plate 26 is made of food-grade rubber, and the soft sealing plate 26 presses on the lower bearing surface of the flat thrust roller bearing 25;

[0063] When the ejector rod of the first electric telescopic rod 18 retracts to the shortest state, the lower bearing surface of the flat thrust roller bearing 25 presses and seals on the soft sealing plate 26, thereby ensuring the isolation effect of the sealing plate 24 in cooperation with the side rod 10, the support net 11, and the top of the filter plate 12, and preventing the solution between the mesh cylinders formed by the support net 11 from overflowing from its top due to centrifugal filtration. With the setting of the flat thrust roller bearing 25, it can also stably support the rotation of the support net 11.

[0064] It should be noted that when the ejector rod of the first electric telescopic rod 18 extends to the longest state, it can drive the sealing plate 24 to move upward by a height of 1.5 meters from the top of the side rod 10.

[0065] Liquid level sensors 204 are screwed on the left and right sides of the sealing plate 24, and the liquid level height signal of the liquid between the mesh cylinders formed by the support net 11 is obtained through the liquid level sensors 204.

[0066] The middle side of the bottom of the sealing plate 24 is evenly fixed with a connecting rod 16 by circumferential screws. The bottom of the connecting rod 16 is fixed with a cover plate 17 by screws, and the gap between the cover plate 17 and the loading leak pipe 14 is 1 mm.

[0067] Refer to Figure 1 、 Figure 2 and Figure 5 Refer to

[0068] The soft plate 31 provides a soft connection for the treatment frame 34, enabling the vibrator 35 to more effectively transfer the vibration it generates to the entire treatment frame 34. With the help of vibration, the non-layered fluidity of the crystal-containing filtrate located above the cold filtration mechanism is improved, making the processes of spraying and drying more effective, and accelerating the sieving efficiency of tyrosine.

[0069] Refer to Figure 1 、 Figure 2 and Figure 3, the automatic drawing mechanism includes a support plate 37 arranged on the left side of the top of the processing frame 34. An electric telescopic rod II 38 is bolted to the support plate 37. The electric telescopic rod II 38 is a stepping motor-driven electric telescopic rod. The top rod of the electric telescopic rod II 38 is flange-connected to a cover plate 39. A first annular groove is provided on the left side of the cover plate 39, and a sealing ring 40 is bonded in the first annular groove. The sealing ring 40 is made of neoprene. When the top rod of the electric telescopic rod II 38 retracts to the shortest state, a second annular groove is provided on the outer edge of the right port of the processing frame 34, and the sealing ring 40 is pressed tightly in the second annular groove, so as to ensure the sealing performance of the cover plate 39 for the right port of the processing frame 34.

[0070] In addition, when the top rod of the electric telescopic rod II 38 fully extends, it can drive the cold filtration mechanism to completely disengage from the processing frame 34.

[0071] Refer to Figure 1 、 Figure 2 、 Figure 3 、 Figure 7 、 Figure 8 、 Figure 9 and Figure 10 , the cold filtration mechanism includes a support frame 41 bolted to the left side of the cover plate 39. A rubber layer is welded to the outer wall of the support frame 41. When the support frame 41 is inserted into the processing frame 34, the rubber layer on the outer wall of the support frame 41 is in a pressed sealing state with the inner wall of the processing frame 34, ensuring the sealing effect when the support frame 41 cooperates with the processing frame 34. A cold conduction frame 42 is fixedly embedded in the support frame 41. The cold conduction frame 42 is a U-shaped frame structure. The cold conduction frame 42 is made of aluminum. Filter strips 43 and cold conduction plates 44 are bolted to the inside of the cold conduction frame 42 evenly and alternately in the front and back. The filter strips 43 and the cold conduction plates 44 are press-fitted with an interference fit. The cold conduction plates 44 are made of aluminum. The filter strips 43 are composed of two ceramic filter strips horizontally staggered up and down. The filtration mesh number of each ceramic filter strip is 12,500. With such a setting, it can sieve the surface residues of water, absolute ethanol, and tyrosine crystals dissolved in absolute ethanol, and tyrosine is intercepted on the upper part of the filter strips 43;

[0072] Under the operation of the vacuum diaphragm pump, a suction force is formed in the lower part of the space inside the processing frame 34, accelerating the sieving process.

[0073] A heat preservation strip block 401 is bolted to the right side of the cover plate 39. The heat preservation strip block 401 is made of heat preservation ceramics. Cold conduction tubes 402 are fixedly embedded in the heat preservation strip block 401 evenly and alternately in the front and back. The cold conduction tubes 402 are made of aluminum. Middle connection cold conduction strips 403 are integrally arranged on the cold conduction tubes 402, and the cold conduction plates 44 are welded to the middle connection cold conduction strips 403. The lower end of the cold conduction tube 402 is screwed to a scroll tube cooler 404. The compressed gas supply end of the scroll tube cooler 404 is connected to an external compressed gas pipe, and the compressed gas pipe is connected to the exhaust end of an electromagnetic air valve I. The intake end of the electromagnetic air valve I is connected to the exhaust end of an external compressed gas station.

[0074] When the vortex tube cooler 404 is supplied with compressed gas, cold air is ejected from its cold air end into the cold conduction tube 402, and the cold degree is transmitted to the middle connection cold conduction strip 403 through the uniformly cold conduction tube 402 at the front and back. The middle connection cold conduction strip 403 transmits the cold degree to each cold conduction plate 44, and the cold conduction frame 42 plays a role in equalizing the cold degree on each cold conduction plate 44.

[0075] When the filtrate is sprayed onto the cold filtration mechanism, it can be quickly cooled by the uniformly arranged cold conduction plates 44, accelerating the filtrate to form a supersaturated state and promoting the precipitation of tyrosine crystals.

[0076] See Figure 1 、 Figure 2 、 Figure 3 and Figure 7 As shown in FIGS.

[0077] When the solenoid valve III is opened, the booster pump I 49 operates, and anhydrous ethanol can be discharged into the moving frame 45 and then sprayed out through the uniformly arranged nozzles 46 at the front and back on the left side of the moving frame 45.

[0078] The mounting plate 51 is bolted to the middle of the right end of the cover plate 39. The motor II 52 is bolted to the mounting plate 51. The motor II 52 is a two-shaft stepper motor. The rotor shaft of the motor II 52 is flange-connected to the rotating shaft 53, and the end of the rotating shaft 53 is flange-connected to the driving wheel 54. The outer wall of the driving wheel 54 is uniformly provided with anti-slip lines, and the anti-slip lines are also provided on the upper surface of the moving frame 45. The driving wheel 54 presses on the top of the moving frame 45.

[0079] The motor II 52 drives the driving wheel 54 to rotate, thereby driving the moving frame 45 to move left and right in the processing frame 34, so that the anhydrous ethanol sprayed out by the uniformly arranged nozzles 46 at the front and back can effectively spray and wash the tyrosine crystals on the cold filtration mechanism.

[0080] The exhaust pipe 66 is threadedly locked at the top of the processing frame 34 and located between the top strip frames 71. The upper end of the exhaust pipe 66 is screwed to the intake end of the solenoid air valve II 67. The exhaust end of the solenoid air valve II 67 is screwed to the side connection air pipe 68. The side connection air pipe 68 is seamlessly melted and connected to the through exhaust pipe 69. The side connection air pipe 68 and the through exhaust pipe 69 are interconnected. The upper end of the through exhaust pipe 69 is flange-connected to the suction end of the pressure-sensing exhaust pump 70.

[0081] When the electromagnetic valve II 67 opens and the pressure-sensitive exhaust pump 70 operates, the ethanol gas and water vapor in the processing box 34 can be accelerated and discharged.

[0082] Refer to Figure 1 、 Figure 2 、 Figure 3 、 Figure 5 and Figure 7 ,The spraying and discharging mechanism includes a discharge pipe 55 connected and arranged on the right side of the bottom of the loading cylinder 5. A heat preservation sleeve 56 is fixedly embedded on the outside of the discharge pipe 55. The heat preservation sleeve 56 and the heat preservation sleeve frame 4 are an integral part. The right end of the discharge pipe 55 is seamlessly welded to the sub-discharge pipe 57, and the discharge pipe 55 is communicated with the sub-discharge pipe 57. The front and rear ends of the sub-discharge pipe 57 are flange-connected to the inlet end of the solenoid valve II 58. The discharge end of the solenoid valve II 58 is flange-connected to the discharge pipe 59. The right end of the discharge pipe 59 is flange-connected to the liquid inlet end of the booster pump II 60. The liquid discharge end of the booster pump II 60 is flange-connected to the connecting pipe 61. The connecting pipe 61 is horizontally and uniformly communicated with the discharge through pipes 62. The discharge through pipes 62 are flange-connected to the inner discharge pipes 63 and the inner discharge pipes 63 are welded in the processing box 34. The front and rear of the bottom of the processing box 34 are uniformly screwed with discharge drip heads 64. The inner diameter of the spray orifice of the discharge drip head 64 is 0.4 mm. On each inner discharge pipe 63, the distance between adjacent discharge drip heads 64 before and after is 4 cm;

[0083] When the solenoid valve II 58 opens and the booster pump II 60 operates, the filtrate in the loading cylinder 5 can be pressurized and discharged into the inner discharge pipes 63, and then sprayed onto the cold filtration mechanism through the uniformly arranged discharge drip heads 64 to achieve distributed crystallization of the filtrate.

[0084] An ethanol gas sensor 65 is bolted and fixed at a position within the processing box 34 and between the inner discharge pipes 63. The ethanol gas concentration within the processing box 34 is detected by the ethanol gas sensor 65, thereby providing conditions for controlling the operation of the heating strip 72 and the pressure-sensitive exhaust pump 70.

[0085] Refer to Figure 1 、 Figure 2 、 Figure 3 and Figure 5 On the left side of the base 1, a support column III 73 is bolted and fixed. At the top of the support column III 73, a control box 74 is bolted and fixed. An expansion board 75 is fixed by insulating pad screws in the upper part of the control box 74; An integrated relay 76 is fixed by screws in the middle of the control box 74. A driver 77 is fixed by screws on the right side of the control box 74. An industrial control computer 78 is fixed by screws on the lid of the control box 74;

[0086] Among them, the I / O power connection pins of the development board 75 are connected to the peripheral 5V DC power supply through a cable. The main power input terminal of the integrated relay 76 is connected to the peripheral power supply through a cable. The main power input terminal of the driver 77 is connected to the peripheral power supply through a cable. The number of drivers 77 is 4. The power control terminals of the first motor 8, the first electric telescopic rod 18, the second electric telescopic rod 38, and the second motor 52 are respectively connected to the power control output terminals of the respective drivers 77 through cables. The first solenoid valve 22, the second solenoid valve 58, the second electromagnetic air valve 67, and the solenoid valve three control connection terminals are connected to the potential control output terminal of the integrated relay 76 through cables. The power supply lines of the vacuum diaphragm pump and the vibrator 35 are connected to the main power output terminal of the relay. The main power input terminal of the relay is connected to the peripheral power supply through a cable. The coil connection terminal of the relay is connected to the potential control output terminal of the integrated relay 76 through a cable.

[0087] The development board 75 includes a control signal receiving module for receiving control signals sent from the industrial control computer 78, a liquid level signal receiving module for receiving liquid level signals sent from the liquid level sensor 204, and an ethanol gas signal receiving module for receiving ethanol gas signals sent from the ethanol gas sensor 65.

[0088] The signal output terminal of the industrial control computer 78 is connected to the signal access pin of the control signal receiving module through a signal line. And the industrial control computer 78 can set the standard liquid level value stored in the planning and processing module through the control signal receiving module. The standard liquid level value satisfies that the volume ratio of the crude tyrosine to distilled water is 1:20. The signal line of the liquid level sensor 204 is connected to the signal receiving pin of the liquid level signal receiving module. The signal line of the ethanol gas sensor 65 is connected to the signal access pin of the ethanol gas signal receiving module.

[0089] The control signal receiving module, the liquid level signal receiving module, and the ethanol gas signal receiving module are connected to the planning and processing module in a transmission manner. The planning and processing module is connected to the rotation speed control output module, the steering and rotation control output module two, the steering and rotation control output module three, the steering and rotation control output module four, the relay control output module one, the relay control output module two, the relay control output module three, the relay control output module four, the relay control output module five, the relay control output module six, the temperature control processing module one, and the temperature control processing module two in a transmission manner.

[0090] The planning and processing module is used to analyze the control signals sent from the control signal receiving module, the liquid level signals sent from the liquid level signal receiving module, and the ethanol gas signals sent from the ethanol gas signal receiving module, and sequentially send control instructions to the rotation speed control output module, the steering and rotation control output module two, the steering and rotation control output module three, the steering and rotation control output module four, the relay control output module one, the relay control output module two, the relay control output module three, the relay control output module four, the relay control output module five, the relay control output module six, the temperature control processing module one, and the temperature control processing module two according to the analysis results.

[0091] The signal output pins of the rotational speed control input module, the second steering and rotational speed control input module, the third steering and rotational speed control input module, and the fourth steering and rotational speed control input module are connected to the signal input ends of each driver 77 through signal lines; the signal output pins of the first relay control input module, the second relay control input module, the third relay control input module, the fourth relay control input module, the fifth relay control input module, and the sixth relay control input module are connected to the signal input ends of each area of the integrated relay 76 through signal lines.

[0092] The rotational speed control input module, the second steering and rotational speed control input module, and the first relay control input module are used to control the operation of the cleaning and filtering mechanism. The rotational speed control input module is used to control the operation of the first motor 8. The second steering and rotational speed control input module is used to control the telescopic movement of the push rod of the first electric telescopic rod 18. The first relay control input module is used to control the opening and closing of the first solenoid valve 22; the second relay control input module is used to control the operation of the spraying and discharging mechanism and is used to control the opening and closing of the second solenoid valve 58; the third steering and rotational speed control input module is used to control the operation of the automatic drawing mechanism and is used to control the telescopic movement of the push rod of the electric telescopic rod 38; the fourth steering and rotational speed control input module, the third relay control input module, and the fourth relay control input module are used to control the operation of the spraying and washing mechanism. The fourth steering and rotational speed control input module is used to control the forward and reverse operation of the second motor 52. The third relay control input module is used to control the opening and closing of the third solenoid valve. The fourth relay control input module is used to control the opening and closing of the second electromagnetic air valve 67; the fifth relay control input module is used to control the operation of the cold filtering mechanism and is used to control the opening and closing of the first electromagnetic air valve; the sixth relay control input module is used to control the operation of the boosting mechanism and is used to control the operation of the vibrator 35. The sixth relay control input module also controls the operation of the vacuum diaphragm pump; the first temperature control processing module is used to control the heating temperature of the heating ring 6. The power supply wire of the heating ring 6 is connected to the power output end of the first thermostat. The power input end of the first thermostat is connected to the external power supply through a cable, and the signal input end of the first thermostat is connected to the signal output pin of the first temperature control processing module through a signal line; the second temperature control processing module is used to control the heating temperature of the heating strip 71. The power supply wire of the heating strip 71 is connected to the power output end of the second thermostat. The power input end of the second thermostat is connected to the external power supply through a cable, and the signal input end of the second thermostat is connected to the signal output pin of the second temperature control processing module through a signal line.

[0093] When the planning processing module receives the feeding control instruction sent by the industrial control computer 78, it issues an instruction to the second steering and rotational speed control input module to control the push rod of the first electric telescopic rod 18 to extend, which can drive the sealing plate 24 to move upward. At this time, the crude tyrosine can be added to the space formed by the support net 11, and then activated carbon is added to the loading leakage pipe 14 and the pressing plate 15 is pressed in.

[0094] When the planning and processing module receives the operation control instruction sent by the industrial control computer 78, it issues an instruction to the second steering and numerical control input module to control the ejector rod of the first electric telescopic rod 18 to retract, driving the sealing plate 24 to move downward until the lower bearing surface of the plane thrust roller bearing 25 presses on the soft sealing ring 26. Then, it issues an instruction to the first relay control and numerical control input module to control the opening of the first solenoid valve 22. The booster pump 21 operates under pressure, extracting distilled water from the distilled water tank into the space formed by the support mesh 11. The liquid level signal receiving module inputs the liquid level signal sent by the liquid level sensor 204 to the planning and processing module in real time. After being converted into a specific liquid level value by the planning and processing module, the average liquid level value is calculated and compared with the standard liquid level value in real time until the average value reaches the standard liquid level value. Then, it issues an instruction to the first relay control and numerical control input module to control the closing of the first solenoid valve 22, and the booster pump 21 stops operating under pressure. Then, it issues an instruction to the speed control and numerical control input module to control the first motor 8 to operate at a speed of 150 r / min, and issues an instruction to the first temperature control processing module to control the heating ring 6 to heat with 90 °C as the standard value; after the speed control and numerical control input module operates for 10 min, it issues an instruction to the second relay control and numerical control input module to control the opening of the second solenoid valve 58, issues an instruction to the sixth relay control and numerical control input module to control the operation of the vibrator 35 and the operation instruction of the vacuum diaphragm pump; after a delay of 2 s, it issues an instruction to the fifth relay control and numerical control input module to control the opening of the first electromagnetic air valve; after a delay of 10 min, it issues an instruction to the fourth steering and numerical control input module for the second motor 52 to execute a reciprocating operation instruction, issues an instruction to the third relay control and numerical control input module to control the opening of the third solenoid valve. After the second motor 52 finishes executing the reciprocating operation instruction, it issues an instruction to the third relay control and numerical control input module to control the closing of the third solenoid valve; then it issues an instruction to the fifth relay control and numerical control input module to control the closing of the first electromagnetic air valve; then it issues an instruction to the relay control and numerical control input module to control the opening of the second electromagnetic air valve 67. The pressure sensing exhaust pump 70 operates under pressure, and issues an instruction to the second temperature control processing module to heat the heating strip 71 with 60 °C as the standard value until the ethanol gas concentration value obtained in real time by the ethanol gas signal receiving module drops to the initial concentration value. Then, it issues an instruction to the relay control and numerical control input module to control the closing of the second electromagnetic air valve 67, and issues an instruction to the second temperature control processing module to stop heating

[0095] After a delay of 10 s, it issues an instruction to the sixth relay control and numerical control input module to control the stopping of the operation of the vibrator 35 and the stopping of the operation of the vacuum diaphragm pump, issues an instruction to the third steering and numerical control input module for the ejector rod of the electric telescopic rod 38 to extend. After the purified tyrosine crystals on the cold filtration mechanism are collected, when the industrial control computer 78 issues a restoration control instruction, it issues an instruction to the third steering and numerical control input module to control the ejector rod of the electric telescopic rod 38 to retract, issues an instruction to the speed control and numerical control input module to control the first motor 8 to stop operating, and issues an instruction to the first temperature control processing module to control the heating ring 6 to stop heating, waiting for the next operation control instruction to be issued;

[0096] The reciprocating operation instruction issued by the steering and numerical control input module four to the motor two 52 is satisfied: driving the nozzle 46 at the bottom of the moving frame 45 to move left and right twice on the filter strip 43, so that the tyrosine crystals on the filter strip 43 are effectively covered by the anhydrous ethanol ejected by the nozzle 46.

[0097] Experimental preparation

[0098] Prepare 20L of crude tyrosine extracted from the hydrolysis of the same batch of blood meal, and divide it into 4 equal parts by volume.

[0099] Example 1

[0100] In the cleaning and filtering mechanism, dissolve 5L of crude tyrosine in distilled water to obtain a crude product full solution, and the volume ratio of the single-use crude tyrosine to distilled water is 1:20; then heat the crude product full solution at a constant temperature and stir it evenly. During the process, add activated carbon for adsorption and filter it while it is hot to obtain a filtrate; the stirring speed is 150r / min, the constant temperature heating temperature is 90°C, and the stirring time is 30min; the weight ratio of activated carbon to crude tyrosine is 1:100.

[0101] Discharge the obtained filtrate to the cold filtering mechanism of the treatment frame through the spraying and discharging mechanism for cooling and filtering to obtain crystals;

[0102] Spray and wash the tyrosine crystals on the cold filtering mechanism with anhydrous ethanol through the spraying and washing mechanism, and the spraying times are two; after the spraying and washing are completed, dry the tyrosine crystals with the heating strip 72, and the drying temperature is 60°C. During the process, discharge the gas in the treatment frame 34 by the exhaust component. After the drying is completed, pull out the cold filtering mechanism by the automatic pulling mechanism and take the tyrosine crystals from the cold filtering mechanism.

[0103] Comparative example 1

[0104] In the cleaning and filtering mechanism, dissolve 5L of crude tyrosine in distilled water to obtain a crude product full solution, and the volume ratio of the single-use crude tyrosine to distilled water is 1:20; then heat the crude product full solution at a constant temperature and stir it evenly. During the process, add activated carbon for adsorption and filter it while it is hot to obtain a filtrate; the stirring speed is 150r / min, the constant temperature heating temperature is 90°C, and the stirring time is 60min; the weight ratio of activated carbon to crude tyrosine is 1:100.

[0105] Discharge the obtained filtrate to the cold filtering mechanism of the treatment frame through the spraying and discharging mechanism for cooling and filtering to obtain crystals.

[0106] Dry the tyrosine crystals with the heating strip 72, and the drying temperature is 90°C. During the process, discharge the gas in the treatment frame 34 by the exhaust component. After the drying is completed, pull out the cold filtering mechanism by the automatic pulling mechanism and take the tyrosine crystals from the cold filtering mechanism.

[0107] Comparative example 2

[0108] Add 5 L of crude tyrosine and distilled water to a dissolution tank for dissolution. When all the crude tyrosine is dissolved in the distilled water, add the dissolution solution to a centrifugal filter, and add activated carbon using the Wuliang tank used in the invention with the application number: CN202410295718.1. The weight ratio of activated carbon to crude tyrosine is 1:100. Then carry out centrifugal filtration, and set a constant temperature heating at 90 °C. The centrifugal filtration time is 60 min.

[0109] After completion, load the obtained filtrate into 8 stainless-steel trays, place the stainless-steel trays in the freezer and cool them to 10 °C and then take them out, and filter through a plate-and-frame filter to obtain crystals. Spray sewage ethanol twice on the tyrosine crystals in the plate-and-frame filter using a pressure spraying machine; 20 minutes after the spraying is completed, take out the tyrosine crystals in the plate-and-frame filter, reload them into the stainless-steel trays, then put them into a hot drying oven, the drying temperature is 60 °C, take them out after drying is completed, and take out the tyrosine crystals from the stainless-steel trays.

[0110] Comparative Example 3

[0111] Add 5 L of crude tyrosine and distilled water to a dissolution tank for dissolution. When all the crude tyrosine is dissolved in the distilled water, add the dissolution solution to a centrifugal filter, and add activated carbon using the Wuliang tank used in the invention with the application number: CN202410295718.1. The weight ratio of activated carbon to crude tyrosine is 1:100. Then carry out centrifugal filtration, and set a constant temperature heating at 90 °C. The centrifugal filtration time is 60 min.

[0112] After completion, load the obtained filtrate into 8 stainless-steel trays, place the stainless-steel trays in the freezer and cool them to 10 °C and then take them out, and filter through a plate-and-frame filter to obtain crystals. Put the stainless-steel trays into a hot dryer, the drying temperature is 90 °C, take them out after drying is completed, and take out the tyrosine crystals from the stainless-steel trays.

[0113] Weigh the final obtained leucine finished products of Example 1, Comparative Example 1, Comparative Example 2, and Comparative Example 3. The measurement environment is a D-class clean area, and a milligram-level weighing instrument is used for weighing. See Table 1 for details:

[0114]

[0115] Table 1

[0116] As can be seen from Table 1, the yield of Example 1 is larger than that of Comparative Example 1 and Comparative Example 3.

[0117] Comparing Example 1 with Comparative Example 2, using a one-stop purification device for purification can reduce the losses during the process.

[0118] Take 0.3 g of the final tyrosine products obtained in Example 1 and Comparative Examples 1 to 3 respectively. The measurement environment is a Class D clean area. Use a high-performance gas chromatograph to detect the purity of tyrosine in each finished product, as well as the proportions of iron salts and minerals. These proportions are obtained by calculating the content of compound molecules in the sample and performing weight calculations. See specifically

[0119] Table 2:

[0120]

[0121] Table 2

[0122] Combining Table 1 and Table 2, it can be seen that when comparing Example 1 with Comparative Example 1 and Comparative Example 3, the amount removed in Example 1 is larger, but the purity of the obtained tyrosine finished product is high, and the contents of other iron salts, minerals and other substances are less. Spraying and washing with absolute ethanol can effectively remove the surface organic impurities that were not effectively removed in the front section of the tyrosine crystals and quickly dissolve and flow down. Moreover, due to its low polarity, absolute ethanol will not dissolve the tyrosine in crystal form, thus improving the crystal purity; and under the subsequent heating, absolute ethanol can quickly volatilize and will not remain on the crystal surface, thus ensuring the purity of the crystal; when comparing Example 1 with Comparative Example 2, using the purification device of the present invention for one-stop treatment can reduce the influence of the external environment on the purification effect.

[0123] The above is only a preferred embodiment of the present invention and is not intended to limit the protection scope of the present invention.

Claims

1. A tyrosine purification process, characterized in that, It includes the following steps: Step 1: Dissolve the crude tyrosine extracted by hydrolyzing pig blood powder in water to obtain a crude product full solution; Step 2: Keep the crude product full solution obtained in Step 1 at a constant temperature and stir it evenly. During the process, add activated carbon for adsorption, and filter it while it is hot to obtain a filtrate; Step 3: Cool and filter the filtrate obtained in Step 2 to obtain crystals; Step 4: Spray and wash the crystals obtained in Step 3 with absolute ethanol; Step 5: Dry and take out; Among them, Steps 1 to 5 are all implemented by a purification device. The purification device includes a base (1). One side of the base (1) is provided with a first support column (2). A cleaning and filtering mechanism is arranged on the first support column (2). The cleaning and filtering mechanism is used to load the crude tyrosine, heat and stir the crude tyrosine with water, and adsorb and filter the crude product full solution; On the other side of the base (1), there is a second support column (28). The top of the second support column (28) is provided with a mounting platform board (29). A boosting mechanism is arranged on the top of the mounting platform board (29), and a processing frame (34) is installed on the boosting mechanism. An automatic drawing mechanism is installed on the processing frame (34). A cold filtering mechanism is arranged on one side of the automatic drawing mechanism and the cold filtering mechanism is inserted into the processing frame (34). The cleaning and filtering mechanism is communicated with the processing frame (34) through a spraying and discharging mechanism; the boosting mechanism is used to increase the fluidity of the filtrate on the cold filtering mechanism; the automatic drawing mechanism is used to drive the cold filtering mechanism to be drawn out and loaded into the processing frame (34); the spraying and discharging mechanism is used to spray and discharge the full solution obtained from the cleaning and filtering mechanism to the cold filtering mechanism; the cold filtering mechanism is used to cool and crystallize the full solution and filter the remaining liquid in the crystals; Top bar frames (71) are evenly arranged on the processing frame (34), and heating bars (72) for heating the filtrate on the cold filtering mechanism are arranged in the top bar frames (71); A spraying and washing mechanism is arranged on the automatic drawing mechanism. The spraying and washing mechanism is used to spray and wash the crystals with absolute ethanol; Exhaust components are evenly arranged on the top bar frames (71). The exhaust components are used to discharge the gas generated by heating the heating bars (72).

2. The tyrosine purification process according to claim 1, characterized in that: In Step 1, the volume ratio of the single-use crude tyrosine to distilled water is 1:

20.

3. The tyrosine purification process according to claim 2, characterized in that: In Step 2, the constant temperature heating temperature is 90 °C, and the stirring time is 60 min; the weight ratio of activated carbon to crude tyrosine is 1:

100.

4. The tyrosine purification process according to claim 3, characterized in that: In Step 4, the number of times of spraying absolute ethanol is two.

5. The tyrosine purification process according to claim 4, wherein: In Step 5, the drying temperature is 60 °C.

6. The tyrosine purification process according to any one of claims 1-5, characterized in that: The cleaning and filtering mechanism includes a heat preservation base plate (3) arranged at the top of the first support column (2). A heat preservation sleeve frame (4) is arranged on the top of the heat preservation base plate (3). A loading cylinder (5) is arranged in the heat preservation sleeve frame (4). A heating ring (6) is arranged at the bottom of the loading cylinder (5). A heat insulation plate (7) is arranged at the center position of the bottom of the loading cylinder (5). A motor one (8) is arranged at the bottom of the heat insulation plate (7). The rotor shaft of the motor one (8) penetrates through the heat insulation plate (7) and is connected with a rotating disc (9); The outer edge of the rotating disk (9) is evenly provided with side rods (10) in the circumferential direction. A support net (11) is arranged between adjacent side rods (10). A filter plate (12) is arranged on the support net (11). A stirring plate (13) is arranged inside the side rod (10). A loading leakage pipe (14) is arranged at the central position of the rotating disk (9). The loading leakage pipe (14) is used for loading activated carbon particles. A pressing plate (15) is arranged in the loading leakage pipe (14) and the pressing plate (15) presses on the activated carbon particles. One side of the heat preservation base plate (3) is provided with a first electric telescopic rod (18). The top rod of the first electric telescopic rod (18) is connected with a connecting plate (19). One side of the connecting plate (19) is provided with a support pipe (20). The top port of the support pipe (20) is connected with a booster water pump (21). The suction pipe of the booster water pump (21) is connected with a discharge hose (201). The lower port of the support pipe (20) is connected with a first solenoid valve (22). The discharge end of the first solenoid valve (22) is connected with a discharge pipe (23). One end of the discharge pipe (23) is provided with a sealing plate (24). The outer edge of the bottom of the sealing plate (24) is provided with a bearing groove. A flat thrust roller bearing (25) is arranged in the bearing groove. A soft sealing plate (26) is arranged at the top of the side rod (10), the support net (11) and the filter plate (12). The soft sealing plate (26) presses on the lower bearing surface of the flat thrust roller bearing (25). Liquid level sensors (204) are arranged on both sides of the sealing plate (24). The bottom of the sealing plate (24) is also connected with a connecting rod (16). The bottom of the connecting rod (16) is connected with a cover plate (17) and the gap between the cover plate (17) and the loading leakage pipe (14) is 1 millimeter.

7. The tyrosine purification process according to claim 6, wherein: The boosting mechanism includes mounting table frames (30) arranged on both sides of a mounting table plate (29). A soft plate (31) is arranged in the mounting table frame (30). A receiving column (32) is inserted into the soft plate (31). A support plate (33) is arranged on the receiving column (32) and the support plate (33) presses on the soft plate (31). The bottom sides of the processing frame (34) are connected to the tops of the receiving columns (32). An exciter (35) is arranged in the middle of the bottom of the processing frame (34). A discharge connecting pipe is arranged on one side of the bottom of the processing frame (34) and the discharge connecting pipe is connected with a soft discharge pipe (36). The automatic drawing mechanism includes a support plate (37) arranged on one side of the top of the processing frame (34). An electric telescopic rod two (38) is installed on the support plate (37). The top rod of the electric telescopic rod two (38) is connected with a cover plate (39). A first annular groove is arranged on one side of the cover plate (39) and a pressure sealing ring (40) is arranged in the first annular groove. A second annular groove is arranged on the outer edge of one port of the processing frame (34) and the pressure sealing ring (40) presses tightly in the second annular groove.

8. The tyrosine purification process according to claim 7, wherein: The cold filtering mechanism includes a support frame (41) connected to the cover plate (39). A cold guiding frame (42) is arranged in the support frame (41). Filtering strips (43) and cold guiding plates (44) are evenly and alternately arranged in the front and back directions in the cold guiding frame (42). A heat preservation strip block (401) is arranged on the cover plate (39). Cooling guide pipes (402) are evenly arranged inside the heat preservation strip block (401) from front to back. A middle connecting cooling strip (403) is arranged on the cooling guide pipes (402), and a cooling plate (44) is connected to the middle connecting cooling strip (403). One end of the cooling guide pipe (402) is connected to a scroll tube cooler (404).

9. The tyrosine purification process according to claim 8, wherein: The spraying and washing mechanism includes a moving frame (45) slidably arranged on the cover plate (39). Spray heads (46) are evenly arranged on the bottom of the moving frame (45) on one side of the processing frame (34) from front to back. One end of the moving frame (45) is connected to a middle connecting pipe (47). A connecting pipe (48) is communicated and arranged on one side of the middle connecting pipe (47). One end of the connecting pipe (48) is connected to a solenoid valve three. The liquid inlet end of the solenoid valve three is connected to a booster pump one (49). The suction end of the booster pump one (49) is connected to a suction hose (50). An installation plate (51) installed on the cover plate (39). A motor two (52) is arranged on the installation plate (51). The rotor shaft of the motor two (52) is connected to a rotating shaft (53). A driving wheel (54) is arranged at the end of the rotating shaft (53), and the driving wheel (54) presses on the top of the moving frame (45). An exhaust pipe (66) is connected to the top of the processing frame (34) and located between the top strip frames (71). One end of the exhaust pipe (66) is connected to an electromagnetic air valve two (67). The exhaust end of the electromagnetic air valve two (67) is connected to a through exhaust pipe (69) through a side connecting air pipe (68). One end of the through exhaust pipe (69) is connected to a pressure-sensitive exhaust pump (70). The spraying and discharging mechanism includes a discharge pipe (55) communicated and arranged on one side of the bottom of the loading cylinder (5). A heat preservation sleeve (56) is arranged on the discharge pipe (55). One end of the discharge pipe (55) is connected to a sub-discharge pipe (57). Solenoid valves two (58) are connected to both ends of the sub-discharge pipe (57). The discharge end of the solenoid valve two (58) is connected to a discharge pipe (59). One end of the discharge pipe (59) is connected to the liquid inlet end of a booster pump two (60). The liquid discharge end of the booster pump two (60) is connected to a through connecting pipe (61). Exhaust through pipes (62) are horizontally and evenly communicated and arranged on the through connecting pipe (61). The exhaust through pipes (62) are connected to inner discharge pipes (63), and the inner discharge pipes (63) are arranged inside the processing frame (34). Drip discharge heads (64) are evenly arranged on the bottom of the processing frame (34) from front to back. An ethanol gas sensor (65) is arranged inside the processing frame (34) and located between the inner discharge pipes (63).

10. The tyrosine purification process according to claim 9, characterized in that: A support column three (73) is further arranged on the base (1). A control box (74) is arranged on the top of the support column three (73). A development board (75), an integrated relay (76) and a driver (77) are arranged inside the control box (74). An industrial control computer (78) is installed on the lid of the control box (74). The development board (75) includes a control signal receiving module for receiving control signals sent from an industrial control computer (78), a liquid level signal receiving module for receiving liquid level signals sent from a liquid level sensor (204), and an ethanol gas signal receiving module for receiving ethanol gas signals sent from an ethanol gas sensor (65); The control signal receiving module, the liquid level signal receiving module, and the ethanol gas signal receiving module are connected to a planning and processing module in a transmission manner. The planning and processing module is connected to a rotation speed control and transmission module, a steering rotation speed control and transmission module II, a steering rotation speed control and transmission module III, a steering rotation speed control and transmission module IV, a relay control and transmission module I, a relay control and transmission module II, a relay control and transmission module III, a relay control and transmission module IV, a relay control and transmission module V, a relay control and transmission module VI, a temperature control processing module I, and a temperature control processing module II in a transmission manner; The planning and processing module is used to analyze the control signals sent from the control signal receiving module, the liquid level signals sent from the liquid level signal receiving module, and the ethanol gas signals sent from the ethanol gas signal receiving module, and sequentially send control instructions to the rotation speed control and transmission module, the steering rotation speed control and transmission module II, the steering rotation speed control and transmission module III, the steering rotation speed control and transmission module IV, the relay control and transmission module I, the relay control and transmission module II, the relay control and transmission module III, the relay control and transmission module IV, the relay control and transmission module V, the relay control and transmission module VI, the temperature control processing module I, and the temperature control processing module II according to the analysis results; The rotation speed control and transmission module, the steering rotation speed control and transmission module II, and the relay control and transmission module I are used to control the operation of the cleaning and filtering mechanism; the relay control and transmission module II is used to control the operation of the spraying and exhausting mechanism; the steering rotation speed control and transmission module III is used to control the operation of the automatic pulling mechanism; the steering rotation speed control and transmission module IV, the relay control and transmission module III, and the relay control and transmission module IV are used to control the operation of the spraying and washing mechanism; the relay control and transmission module V is used to control the operation of the cold filtering mechanism; the relay control and transmission module VI is used to control the operation of the boosting mechanism; the temperature control processing module I is used to control the heating temperature of the heating ring (6); the temperature control processing module II is used to control the heating temperature of the heating strip (71).

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