Left auricle closing device

Abstract

The invention relates to a left auricle closing device, and belongs to the technical field of medical instruments. The first pushing assembly and the knob assembly are matched to drive the first conveying pipe to move and rotate in the axial direction, the second pushing assembly drives the second conveying pipe to move in the axial direction, the third pushing assembly drives the controllable catheter to move in the axial direction, and the implanter and the locking device can be exposed out of the controllable catheter and retract into the controllable catheter; through cooperation of the rotary knob assembly, the first pushing assembly, the second pushing assembly and the third pushing assembly, the implanting device and the locking device can be accurately conveyed and released in the left auricle closing operation process, and left auricle tissue is pulled and wound on the implanting device and clamped between the implanting device and the locking device; and the implanter and the locking device of the implant are not easy to fall off. The left atrial appendage closing device is simple in operation steps and convenient for doctors to operate.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a left atrial appendage closure device. Background Art

[0002] Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia clinically, with an AF prevalence of 0.5% to 1.3% in the general population. The greatest risk of AF is the risk of embolic events, such as acute cerebral infarction and acute myocardial infarction. In patients with nonvalvular AF, over 90% of thrombi observed by transesophageal echocardiography (TEE) or autopsy series originate from the left atrial appendage (LAA). This observation has spurred the development of LAA exclusion techniques, including endovascular occlusion, surgical suturing, stapling, and resection, as non-pharmacological approaches to reduce stroke risk. Surgical resection, stapling, suturing, or direct ligation of the LAA is a major procedure requiring thoracotomy and prolonged recovery time. These procedures are invasive, have low complete closure rates, and increase the risk of infection and adverse anesthesia reactions. Furthermore, they are expensive and time-consuming. Thoracoscopic closure of the LAA to prevent embolic events associated with AF holds great promise. However, with current technology, simply resecting or occluding the LAA is too invasive and carries a high risk of complications. Therefore, transcatheter left atrial appendage occlusion (LAAO) has become an acceptable option for preventing AF-related stroke and systemic embolism in patients at increased risk of bleeding.

[0003] However, existing left atrial appendage occlusion devices have poor fit and cannot completely cover the opening of the left atrial appendage, which easily forms a residual cavity, leading to leakage around the device (PDL) and increasing the risk of thrombosis. In addition, existing left atrial appendage occlusion devices also have the defect that the implant is easy to fall off.

[0004] Therefore, it is very necessary to design a left atrial appendage closure device in which the implant is not easy to fall off. Summary of the Invention

[0005] The purpose of the present invention is to overcome the shortcomings of the prior art and provide a left atrial appendage closure device in which the implant is not easily dislodged.

[0006] To achieve the above object, the technical solution adopted by the present invention is:

[0007] A left atrial appendage closure device includes a tube assembly, an implanter, a locker, a handle, a knob assembly, a first pushing assembly, a second pushing assembly, and a third pushing assembly, wherein:

[0008] The tube assembly includes a first delivery tube, a second delivery tube and a controllable catheter, wherein the second delivery tube is sleeved on the first delivery tube, and the controllable catheter is sleeved on the second delivery tube. The handle includes a first shell, and the first shell is sleeved on the controllable catheter.

[0009] The implantor is disposed at one end of the first delivery tube away from the handle;

[0010] The locker is movably connected to the implantor through a connecting shaft. The locker is located between the implantor and the second delivery tube, and the locker abuts against one end of the second delivery tube away from the handle;

[0011] The knob assembly, the first pushing assembly, the second pushing assembly and the third pushing assembly are respectively disposed on the handle;

[0012] The knob assembly is connected to the first delivery tube, and the knob assembly is used to drive the first delivery tube to rotate;

[0013] The first pushing assembly is connected to the first delivery tube, and the first pushing assembly is used to drive the first delivery tube to move axially along the first delivery tube;

[0014] The second pushing assembly is connected to the second delivery tube, and the second pushing assembly is used to drive the second delivery tube to move axially along the second delivery tube;

[0015] The third pushing assembly is connected to the controllable catheter, and the third pushing assembly is used to drive the third pushing assembly to move axially along the controllable catheter.

[0016] Preferably, the knob assembly includes a first knob and a first knob joint. The first knob joint is connected to the first knob. The first knob joint and the first knob are both sleeved on the first delivery tube. The first knob joint is received in the first housing and is rotationally matched with the first housing.

[0017] Further preferably, the first knob and the first delivery tube are engaged in a snap-fit manner through a limit groove and a limit protrusion; the limit groove is provided on the outer wall of the first delivery tube and extends axially along the first delivery tube. The limit protrusions correspond to and match the limit grooves one by one. One end of the limit protrusion is received in the limit groove, and the other end of the limit protrusion is provided on the inner wall of the first knob.

[0018] Further preferably, the number of the limit grooves is not less than three and they are equally spaced along the circumferential direction of the first delivery tube. The limit grooves form a spline structure on the outer wall of the first delivery tube.

[0019] Preferably, the first pushing component includes a first slider, a first sliding rod and a first control block. A first sliding groove is provided on the first housing. The first slider is located inside the first housing and connected to the first delivery pipe. One end of the first sliding rod is connected to the first slider, and the other end of the first sliding rod passes through the first sliding groove and is connected to the first slider. The first slider is located outside the first housing and is in sliding fit with the first sliding groove.

[0020] Preferably, the second pushing component includes a second slider, a second sliding rod and a second control block. A second sliding groove is provided on the first housing. The second slider is located inside the second housing and connected to the second delivery pipe. One end of the second sliding rod is connected to the second slider, and the other end of the second sliding rod passes through the second sliding groove and is connected to the second slider. The second slider is located outside the first housing and is in sliding fit with the second sliding groove.

[0021] Preferably, the third pushing component includes a third slider, a third sliding rod and a third control block. A third sliding groove is provided on the first housing. The third slider is located inside the second housing and connected to the controllable catheter. One end of the third sliding rod is connected to the third slider, and the other end of the third sliding rod passes through the third sliding groove and is connected to the third slider. The third slider is located outside the first housing and is in sliding fit with the third sliding groove.

[0022] Preferably, the implantor includes an implantor connector, a connecting shaft and a plurality of implanting claws arranged circumferentially along the implantor connector. The implantor connector is sleeved on the connecting shaft, and the connecting shaft is sleeved on one end of the first delivery pipe away from the handle; a first locking protrusion extending axially along the first delivery pipe is provided on the outer wall of one end of the first delivery pipe away from the handle, and a second locking protrusion extending axially along the connecting shaft is provided on the inner wall of the connecting shaft. The first locking protrusion is adapted to the second locking protrusion.

[0023] More preferably, a locking block is provided on one side of the first locking protrusion facing the second locking protrusion, and a locking groove is provided on one side of the second locking protrusion facing the first locking protrusion. The locking groove is adapted to the locking block.

[0024] Preferably, the lock includes an anchor barb connector and a plurality of locking barbs arranged circumferentially along the anchor barb connector; the anchor barb connector is sleeved on the connecting shaft, and the anchor barb connector is in sliding fit with the connecting shaft. The lock is located between the implantor and the second delivery pipe, and the anchor barb connector abuts against the second delivery pipe.

[0025] Further preferably, a clamping groove is provided on the anchor spike joint, and a clamping protrusion adapted to the clamping groove is provided on the end face of the second delivery tube.

[0026] Preferably, the handle further includes a third housing, the third housing is disposed on the first housing and communicates with the inner space of the first housing. The left atrial appendage closing device further includes a bending adjustment assembly, the bending adjustment assembly includes a bending adapter, a connecting rod and a second knob. The second knob is located outside the third housing. One end of the connecting rod is connected to the second knob, the connecting rod is threadedly connected to the first housing, and the other end of the connecting rod extends into the first housing and is connected to the bending adapter.

[0027] The controllable catheter includes a fixing ring, a first catheter segment and a second catheter segment connected in sequence. The fixing ring is connected with a traction wire, and the end of the traction wire away from the fixing ring is connected to the bending adapter.

[0028] Further preferably, the bending adjustment assembly further includes a stabilizing block. The stabilizing block is sleeved on the connecting rod, the stabilizing block is threadedly connected to the connecting rod, and the stabilizing block is slidably matched with the inner wall of the first housing.

[0029] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0030] Through the cooperation of the first pushing assembly and the knob assembly, the first delivery tube is driven to axially move and rotate. The second delivery tube is driven to axially move by the second pushing assembly, and the controllable catheter is driven to axially move by the third pushing assembly, so that the implantor and the lock can be exposed from the controllable catheter and retracted into the controllable catheter. Through the cooperation of the knob assembly, the first pushing assembly, the second pushing assembly and the third pushing assembly, the implantor and the lock can be accurately delivered and released during the left atrial appendage closing operation, and the left atrial appendage tissue can be pulled and wound around the implantor and clamped between the implantor and the lock, so that the implantor and the lock are not easily detached. The operation steps of the left atrial appendage closing device of the present invention are simple and convenient for doctors to operate. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 is a cross-sectional view of the left atrial appendage closing device provided by the present invention;

[0032] Figure 2 is a front view of the left atrial appendage closing device provided by the present invention;

[0033] Figure 3 is Figure 2 an enlarged view of part A in

[0034] Figure 4 a schematic diagram of the first delivery tube and the connecting shaft in a locked state;

[0035] Figure 5 Schematic diagram of the first delivery tube and the connecting shaft in the unlocked state.

[0036] In the figure, 1 is the tube assembly, 11 is the first delivery tube, 111 is the first tube section, 1111 is the locking projection, 1112 is the locking block, 112 is the second tube section, 113 is the third tube section, 12 is the second delivery tube, 13 is the controllable catheter, 131 is the first catheter section, 132 is the second catheter, 133 is the fixing ring, 2 is the implantor, 21 - implanting claw, 22 - implantor adapter, 23 is the connecting shaft, 231 is the locking projection, 3 is the lock, 31 is the locking anchor barb, 32 is the barb adapter, 321 is the clamping groove, 4 is the handle, 41 is the first housing, 411 is the first chute, 412 is the second chute, 413 is the third chute, 42 is the second housing, 43 - the third housing, 5 is the knob assembly, 51 is the first knob, 52 is the first knob adapter, 53 is the second knob adapter, 6 is the first pushing assembly, 61 is the first slider, 62 is the first slide bar, 63 is the first control block, 7 is the second pushing assembly, 71 is the second slider, 72 is the second slide bar, 73 is the second control block, 8 is the third pushing assembly, 81 is the third slider, 82 is the third slide bar, 83 is the third control block, 9 is the bending adjustment assembly, 91 is the bending adjustment adapter, 92 is the stabilizing block, 93 is the connecting rod, 94 is the second knob. Detailed implementation manners

[0037] To better illustrate the object, technical solution and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments.

[0038] In the description of the present invention, it should be noted that the terms "first", "second", "third", etc. are only used for descriptive purposes and cannot be understood as indicating the number of the indicated technical features. Thus, the features defined with "first", "second", "third", etc. may explicitly or implicitly include at least one of such features.

[0039] In the description of the present invention, unless otherwise clearly defined and limited, the first feature being "on" or "under" the second feature may be that the first and second features are in direct contact, or the first and second features are indirectly in contact through an intermediate medium. Moreover, the first feature being "above", "over" and "on top of" the second feature may be that the first feature is directly above or obliquely above the second feature, or merely indicates that the first feature has a higher horizontal height than the second feature. The first feature being "under", "below" and "beneath" the second feature may be that the first feature is directly below or obliquely below the second feature, or merely indicates that the first feature has a lower horizontal height than the second feature.

[0040] In all the directional indicators (such as up, down, inside, outside) in the present invention, they are only used to explain the relative positional relationship, movement condition, etc. between various components in a specific posture (as shown in the attached drawings). If this specific posture changes, then the directional indicators will change accordingly.

[0041] In the description of the present invention, it should also be noted that the terms "comprise" and "have" and any variations thereof are intended to cover non-exclusive inclusion.

[0042] In the description of the present invention, it should be noted that unless otherwise clearly specified and defined, the terms "connected", "connected to", and "arranged" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection; it can be directly connected, or indirectly connected through an intermediate medium, and it can be the communication inside two components.

[0043] For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0044] If there is no special description, all the embodiments of the present invention can be combined with each other to form a new technical solution.

[0045] Please refer to Figures 1 to 5 , the present invention provides a left atrial appendage closure device. The left atrial appendage closure device includes a tube assembly 1, an implantor 2, a lock 3, a handle 4, a knob assembly 5, a first pushing assembly 6, a second pushing assembly 7, and a third pushing assembly 8. Among them,

[0046] The tube assembly 1 includes a first delivery tube 11, a second delivery tube 12, and a controllable catheter 13. The second delivery tube 12 is sleeved on the first delivery tube 11, and the controllable catheter 13 is sleeved on the second delivery tube 12. The handle 4 includes a first housing 41, and the first housing 41 is sleeved on the controllable catheter 13;

[0047] The implantor 2 is arranged at one end of the first delivery tube 11 away from the handle 4;

[0048] The lock 3 is movably connected to the implantor 2 through a connecting shaft 23. The lock 3 is located between the implantor 2 and the second delivery tube 12, and the lock 3 abuts against one end of the second delivery tube 12 away from the handle 4;

[0049] The knob assembly 5, the first pushing assembly 6, the second pushing assembly 7, and the third pushing assembly 8 are respectively arranged on the handle 4;

[0050] The knob assembly 5 is connected to the first delivery tube 11, and the knob assembly 5 is used to drive the first delivery tube 11 to rotate;

[0051] The first pushing component 6 is connected to the first conveying pipe 11, and the first pushing component 6 is used to drive the first conveying pipe 11 to move axially along the first conveying pipe 11;

[0052] The second pushing component 7 is connected to the second conveying pipe 12, and the second pushing component 7 is used to drive the second conveying pipe 12 to move axially along the second conveying pipe 12;

[0053] The third pushing component 8 is connected to the controllable catheter 13, and the third pushing component 8 is used to drive the third pushing component 8 to move axially along the controllable catheter 13.

[0054] Through the cooperation of the first pushing component 6 and the knob component 5, the present invention can drive the first conveying pipe 11 to move axially and rotate. The second conveying pipe 12 is driven to move axially by the second pushing component 7, and the controllable catheter 13 is driven to move axially by the third pushing component 8, so that the implantor 2 and the lock 3 can be exposed from the controllable catheter 13 or retracted into the controllable catheter 13. Through the cooperation of the knob component 5, the first pushing component 6, the second pushing component 7 and the third pushing component 8, the present invention can accurately convey and release the implantor 2 and the lock 3 during the left atrial appendage closure operation, and the left atrial appendage tissue is pulled and wound by the implantor 2 and clamped between the implantor 2 and the lock 3, so that the implantor 2 and the lock 3 as implants are not easily detached. In addition, the operation steps of the left atrial appendage closure device of the present invention are simple and convenient for doctors to operate.

[0055] In some embodiments, the knob component 5 includes a first knob 51 and a first knob joint 52. The first knob joint 52 is connected to the first knob 51. Both the first knob joint 52 and the first knob 51 are sleeved on the first conveying pipe 11. The first knob joint 52 is received in the first housing 41 and is rotationally matched with the first housing 41. When in use, it is convenient for the operator to hold the first housing 41 and rotate the first knob 51, which can drive the first conveying pipe 11 to rotate.

[0056] The first knob 51 and the first conveying pipe 11 are in clamping fit through a limit groove and a limit protrusion.

[0057] The limit groove is arranged on the outer wall of the first conveying pipe 11 and extends axially along the first conveying pipe 11. The limit protrusions correspond to and are adapted to the limit grooves one by one. One end of the limit protrusion is received in the limit groove, and the other end of the limit protrusion is arranged on the inner wall of the first knob 51.

[0058] The number of the limiting grooves is not less than three and they are evenly distributed at equal intervals along the circumferential direction of the first conveying pipe 11. The limiting grooves form a spline structure on the outer wall of the first conveying pipe 11. Such a structural design can increase the rotational torque on the premise of not hindering the axial movement of the first conveying pipe 11, which is beneficial to improving the accuracy and stability of the first knob 51 in controlling the rotation start and stop positions of the first conveying pipe 11.

[0059] Specifically, there is a gap between the first knob joint 52 and the first conveying pipe 11, or the first knob joint 52 is slidably engaged with the first conveying pipe 11.

[0060] Specifically, the first knob 51 is located between the first housing 41 and the second housing 42. A pointer mark is provided on the outer wall of the first knob 51, and a rotation angle mark is provided on the outer wall of the first housing 41 at one end close to the first knob 51, which is convenient for the operator to determine the rotation range of the first conveying pipe 11.

[0061] Specifically, the handle 4 further includes a second housing 42, and the knob assembly 5 further includes a second knob joint 53. The second knob joint 53 is connected to the first knob 51, the second knob joint 53 is sleeved on the first conveying pipe 11, and the second knob joint 53 is received in the second housing 42 and is threadedly connected to the second housing 42.

[0062] There is a gap between the second knob joint 53 and the first conveying pipe 11, or the second knob joint 53 is slidably engaged with the first conveying pipe 11.

[0063] The second housing 42 is provided with a through hole 421 adapted to the first conveying pipe 11.

[0064] The first knob joint 52, the first knob 51, and the second knob joint 54 are integrally formed and connected in sequence.

[0065] In some embodiments, the first pushing assembly 6 includes a first slider 61, a first sliding rod 62, and a first control block 63. A first sliding groove 411 is provided on the first housing 41. The first slider 61 is located inside the first housing 41 and is connected to the first conveying pipe 11. One end of the first sliding rod 62 is connected to the first slider 61, and the other end of the first sliding rod 62 passes through the first sliding groove 411 and is connected to the first slider 61. The first slider 61 is located outside the first housing 41 and is slidably engaged with the first sliding groove 411.

[0066] Specifically, distance scales are provided on the outer side of the first sliding groove 411.

[0067] In some embodiments, the second pushing assembly 7 includes a second slider 71, a second sliding rod 72, and a second control block 73. A second sliding groove 412 is provided on the first housing 41. The second slider 71 is located inside the second housing 41 and is connected to the second delivery tube 12. One end of the second sliding rod 72 is connected to the second slider 71, and the other end of the second sliding rod 72 passes through the second sliding groove 412 and is then connected to the second slider 71. The second slider 71 is located outside the first housing 41 and is in sliding fit with the second sliding groove 412.

[0068] Specifically, distance scales are provided on the outer side of the second sliding groove 412.

[0069] In some embodiments, the third pushing assembly 8 includes a third slider 81, a third sliding rod 82, and a third control block 83. A third sliding groove 413 is provided on the first housing 41. The third slider 81 is located inside the second housing 41 and is connected to the controllable catheter 13. One end of the third sliding rod 82 is connected to the third slider 81, and the other end of the third sliding rod 82 passes through the third sliding groove 413 and is then connected to the third slider 81. The third slider 81 is located outside the first housing 41 and is in sliding fit with the third sliding groove 413.

[0070] Specifically, distance scales are provided on the outer side of the third sliding groove 413.

[0071] It can be understood that the present invention does not particularly limit the lengths of the first sliding groove 411, the second sliding groove 412, and the third sliding groove 413, and those skilled in the art can design the sizes of the respective sliding grooves according to actual situations.

[0072] In some embodiments, the implantor 2 includes an implantor connector 22, a connecting shaft 23, and a plurality of implanting claws 21 arranged circumferentially around the implantor connector 22. The implantor connector 22 is sleeved on the connecting shaft 23, and the implantor connector 22 is fixedly connected to the connecting shaft 23. The connecting shaft 23 is sleeved on one end of the first delivery tube 11 away from the handle 4; a first locking protrusion 1111 extending axially along the first delivery tube 11 is provided on the outer wall of one end of the first delivery tube 11 away from the handle 4, and a second locking protrusion 231 extending axially along the connecting shaft 23 is provided on the inner wall of the connecting shaft 23. The first locking protrusion 1111 is adapted to the second locking protrusion 231.

[0073] Specifically, a locking block 1111 is provided on the side of the first locking protrusion 1111 facing the second locking protrusion 231, and a locking groove (not shown in the figure) is provided on the side of the second locking protrusion 231 facing the first locking protrusion 1111. The locking groove is adapted to the locking block 1112.

[0074] During use, when the implantor 2 is pushed to the center of the left atrial appendage opening and the implanting claw 21 touches the left atrial appendage, rotate the first delivery tube 11 counterclockwise so that the first locking protrusion 1111 abuts against the second locking protrusion 231 and the locking block 1111 is inserted into the locking groove. At this time, the first delivery tube 11 and the connecting shaft 23 are in the locking state as shown in Figure 4 Continue to rotate the first delivery tube 11 counterclockwise, which can drive the connecting shaft 23 to rotate, and further drive the implantor joint 22 and the implanting claw 21 to rotate, so that the left atrial appendage tissue is pulled and wound around the implanting claw 21 and the connecting shaft 23.

[0075] When it is necessary to release the implantor 2, rotate the first delivery tube 11 clockwise so that the first locking protrusion 1111 moves away from the second locking protrusion 231 and the locking block 1111 disengages from the locking groove. At this time, the first delivery tube 11 and the connecting shaft 23 are in the unlocking state as shown in Figure 5 Shown.

[0076] Specifically, the material of the implanting claw 21 is shape memory metal or shape memory alloy.

[0077] Specifically, in the natural state, several implanting claws 21 are intertwined into a semi-cage shape.

[0078] Specifically, the lock 3 includes an anchor barb joint 32 and several locking barbs 31 arranged circumferentially along the anchor barb joint 32; the anchor barb joint 32 is sleeved on the connecting shaft 23, the anchor barb joint 32 is slidably matched with the connecting shaft 23, the lock 3 is located between the implantor 2 and the second delivery tube 12, and the anchor barb joint 32 abuts against the second delivery tube 12.

[0079] A clamping groove 321 is arranged on the anchor barb joint 32, and a clamping protrusion (not shown in the figure) adapted to the clamping groove 321 is arranged on the end face of the second delivery tube 12.

[0080] Specifically, in the natural state, several locking barbs 31 are intertwined into an umbrella shape.

[0081] In some embodiments, the first delivery tube 11 includes a first tube section 111, a second tube section 112 and a third tube section 113 connected in sequence. The locking protrusion 1111 is arranged at one end of the first tube section 111 far from the second tube section 112. The first slider 61 of the first pushing assembly 6 is sleeved on the second tube section 112 and is threadedly connected with the second tube section 112, and the limiting groove is arranged on the third tube section 113.

[0082] Specifically, the first tube section 111 extends out of the second delivery tube 12 and is threadedly connected or integrally formed with the second tube section 112, and the second tube section 112 is threadedly connected or integrally formed with the third tube section 113.

[0083] Specifically, the outer diameter of the first pipe segment 111 is smaller than that of the second pipe segment 112, and the outer diameter of the second pipe segment 112 is smaller than that of the third pipe segment 113.

[0084] Specifically, both the second pipe segment 112 and the third pipe segment 113 are located within the handle 4.

[0085] In some embodiments, the handle 4 further includes a third housing 43. The third housing 43 is disposed on the first housing 41 and is in communication with the internal space of the first housing 41. The left atrial appendage closure device further includes a bending adjustment assembly 9. The bending adjustment assembly 9 includes a bending adapter 91, a connecting rod 93, and a second knob 94. The second knob 94 is located outside the third housing 43. One end of the connecting rod 93 is connected to the second knob 94. The connecting rod 93 is threadedly connected to the first housing 41. The other end of the connecting rod 93 extends into the first housing 41 and is connected to the bending adapter 91.

[0086] The controllable catheter 3 includes a fixing ring 133, a first catheter segment 131, and a second catheter segment 132 that are connected in sequence. The fixing ring 133 is connected to a traction wire (not shown in the figure). The end of the traction wire away from the fixing ring 133 is connected to the bending adapter 91.

[0087] Specifically, the bending adjustment assembly 9 further includes a stabilizing block 92. The stabilizing block 92 is sleeved on the connecting rod 93. The stabilizing block 92 is threadedly connected to the connecting rod 93. The stabilizing block 92 is slidably engaged with the inner wall of the first housing 41.

[0088] During use, rotate the second knob 94 to drive the connecting rod 93 to rotate, drive the bending adapter 9 to move along the axial direction of the connecting rod 93, thereby pulling or releasing the traction wire, and further achieving the purpose of controlling the bending angle of the controllable catheter 3. The bending angle of the first catheter segment 131 is 0 to 90°. When the bending angle is 0°, the first catheter segment 131 is in an unbent state.

[0089] Specifically, the traction wire can be a wire.

[0090] Specifically, the hardness of the first catheter segment 131 is smaller than that of the second catheter segment 132. For example, the hardness of the first catheter segment 131 is 20 to 50D, and the hardness of the second catheter segment 132 is not less than 60D.

[0091] The first catheter segment 131 has a certain elasticity. When subjected to the pulling force of the traction wire, the first catheter segment 131 bends. After the pulling force of the traction wire disappears, the first catheter segment 131 returns to its natural shape.

[0092] It is understandable that the present invention does not particularly limit the sizes of the components (such as the first delivery tube 11, the second delivery tube 12, the controllable catheter 13, etc.) in the left atrial appendage closing device, and they can be designed according to the actual application (such as the structure and size of the left atrial appendage).

[0093] Under X-ray monitoring, puncture the femoral vein, insert a vascular sheath, introduce a guide wire, puncture the atrial septum, and establish a passage through the femoral vein, inferior vena cava, right atrium, and left atrium; send a pigtail catheter along the guide wire into the left atrium to perform angiography on the left atrial appendage to determine the structure and size of the left atrial appendage. Then withdraw the pigtail catheter and the guide wire, and use the left atrial appendage closing device of the present invention to perform the left atrial appendage closing operation, which may include the following process:

[0094] Send the distal end of the controllable catheter 13 into the left atrial appendage through the vascular sheath, and during this period, the bending degree of the distal end of the controllable catheter 13 can be adjusted through the bending adjustment assembly 9.

[0095] Through the first pushing assembly 6, send the distal end (i.e., the end far from the handle 4) of the tube assembly 1 pre-loaded with the implantor 2 and the lock 3 along the controllable catheter 13 to a predetermined position. During the delivery process, both the implantor 2 and the lock 3 are in a contracted state.

[0096] Through the third pushing assembly 8, withdraw the controllable catheter 13 until the implantor 2 is exposed. After the implantor 2 is exposed, the implanting claws 21 naturally expand. Drive the first delivery catheter 11 to axially move through the first pushing assembly 6, and then drive the implantor 2 to axially move until the implanting claws 21 touch the left atrial appendage tissue; then drive the first delivery tube 11 to rotate through the knob assembly 5, and then drive the implantor 2 to rotate, so that the left atrial appendage tissue is drawn and wound around the implanting claws 21 and the connecting shaft 23.

[0097] After confirming the closure of the left atrial appendage by comparing DSA fluoroscopy, angiography, and TEE, drive the second delivery tube 12 to axially move through the second pushing assembly 7, and push the lock 3 out of the controllable catheter 13. After the lock 3 is pushed out, the locking anchor spines 31 naturally expand, and then the locking anchor spines 31 are engaged with the left atrial appendage tissue.

[0098] Rotate the first delivery tube 11 clockwise (as indicated by the arrow in Figure 5 ), so that the first locking protrusion 1111 is away from the second locking protrusion 231, and the locking block 1112 is disengaged from the locking groove. At this time, the first delivery tube 11 and the connecting shaft 23 are in the unlocked state as shown in Figure 5 , and withdraw the first delivery tube 11 from the connecting shaft 23 through the first pushing assembly 6, thereby completing the release step of the implantor 2 and the lock 3.

[0099] After release, withdraw the tube assembly 1 from the body.

[0100] All steps before the release step are reversible.

[0101] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit the protection scope of the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be modified or equivalently replaced without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. A left atrial appendage occlusion device, characterized in that, It includes a tube assembly, an inserter, a lock, a handle, a knob assembly, a first pushing assembly, a second pushing assembly and a third pushing assembly. Among them, the tube assembly includes a first delivery tube, a second delivery tube and a controllable catheter. The second delivery tube is sleeved on the first delivery tube, and the controllable catheter is sleeved on the second delivery tube. The handle includes a first housing, and the first housing is sleeved on the controllable catheter; the inserter is arranged at one end of the first delivery tube away from the handle; the lock is movably connected to the inserter through a connecting shaft. The lock is located between the inserter and the second delivery tube, and the lock abuts against one end of the second delivery tube away from the handle; the knob assembly, the first pushing assembly, the second pushing assembly and the third pushing assembly are respectively arranged on the handle; the knob assembly is connected to the first delivery tube, and the knob assembly is used to drive the first delivery tube to rotate; the first pushing assembly is connected to the first delivery tube, and the first pushing assembly is used to drive the first delivery tube to move axially along the first delivery tube; the second pushing assembly is connected to the second delivery tube, and the second pushing assembly is used to drive the second delivery tube to move axially along the second delivery tube; the third pushing assembly is connected to the controllable catheter, and the third pushing assembly is used to drive the third pushing assembly to move axially along the controllable catheter.

2. The left atrial appendage occlusion device according to claim 1, wherein The knob assembly includes a first knob and a first knob joint. The first knob joint is connected to the first knob. Both the first knob joint and the first knob are sleeved on the first delivery tube. The first knob joint is accommodated in the first housing and is rotationally matched with the first housing.

3. The left atrial appendage occlusion device according to claim 2, wherein, The first knob and the first delivery tube are in a clamping fit through a limiting groove and a limiting protrusion. The limiting groove is arranged on the outer wall of the first delivery tube and extends axially along the first delivery tube. The limiting protrusions correspond to and match the limiting grooves one by one. One end of the limiting protrusion is accommodated in the limiting groove, and the other end of the limiting protrusion is arranged on the inner wall of the first knob; and / or, the number of the limiting grooves is not less than three and they are equally spaced along the circumferential direction of the first delivery tube. The limiting grooves form a spline structure on the outer wall of the first delivery tube.

4. The left atrial appendage occlusion device according to claim 1, wherein The first pushing assembly includes a first slider, a first slide bar and a first control block. A first chute is arranged on the first housing. The first slider is located in the first housing and is connected to the first delivery tube. One end of the first slide bar is connected to the first slider, and the other end of the first slide bar passes through the first chute and is connected to the first slider. The first slider is located outside the first housing and is slidably matched with the first chute; And / or, the second pushing component includes a second slider, a second sliding rod and a second control block. A second sliding groove is provided on the first housing. The second slider is located inside the second housing and connected to the second delivery tube. One end of the second sliding rod is connected to the second slider, and the other end of the second sliding rod passes through the second sliding groove and is connected to the second slider. The second slider is located outside the first housing and is slidably engaged with the second sliding groove; And / or, the third pushing component includes a third slider, a third sliding rod and a third control block. A third sliding groove is provided on the first housing. The third slider is located inside the second housing and connected to the controllable catheter. One end of the third sliding rod is connected to the third slider, and the other end of the third sliding rod passes through the third sliding groove and is connected to the third slider. The third slider is located outside the first housing and is slidably engaged with the third sliding groove.

5. The left atrial appendage occlusion device according to claim 1, characterized in that, The implantor includes an implantor connector, a connecting shaft and a plurality of implanting claws arranged circumferentially along the implantor connector. The implantor connector is sleeved on the connecting shaft, and the connecting shaft is sleeved on one end of the first delivery tube away from the handle; a first locking protrusion extending axially along the first delivery tube is provided on the outer wall of one end of the first delivery tube away from the handle, and a second locking protrusion extending axially along the connecting shaft is provided on the inner wall of the connecting shaft. The first locking protrusion and the second locking protrusion are adapted to each other.

6. The left atrial appendage occlusion device according to claim 5, wherein A locking block is provided on one side of the first locking protrusion facing the second locking protrusion, and a locking groove is provided on one side of the second locking protrusion facing the first locking protrusion. The locking groove and the locking block are adapted to each other.

7. The left atrial appendage closure device according to claim 1, characterized in that, The lock includes an anchor barb connector and a plurality of locking barbs arranged circumferentially along the anchor barb connector; the anchor barb connector is sleeved on the connecting shaft, and the anchor barb connector is slidably engaged with the connecting shaft. The lock is located between the implantor and the second delivery tube, and the anchor barb connector abuts against the second delivery tube.

8. The left atrial appendage occlusion device according to claim 7, wherein A clamping groove is provided on the anchor barb connector, and a clamping protrusion adapted to the clamping groove is provided on the end face of the second delivery tube.

9. The left atrial appendage closure device according to claim 1, wherein, The handle further includes a third housing, which is provided on the first housing and communicates with the internal space of the first housing. The left atrial appendage occlusion device further includes a bending adjustment component, which includes a bending adjustment joint, a connecting rod and a second knob. The second knob is located outside the third housing. One end of the connecting rod is connected to the second knob, the connecting rod is threadedly connected to the first housing, and the other end of the connecting rod extends into the first housing and is connected to the bending adjustment joint; The controllable catheter includes a fixed ring, a first catheter segment and a second catheter segment connected in sequence. The fixed ring is connected with a traction wire, and the end of the traction wire away from the fixed ring is connected to the bending adjustment joint.

10. The left atrial appendage occlusion device according to claim 9, characterized in that, The bending adjustment component further includes a stabilizing block, which is sleeved on the connecting rod, the stabilizing block is threadedly connected to the connecting rod, and the stabilizing block is slidably engaged with the inner wall of the first housing.

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