Traditional Chinese medicine preparation for treating intractable skin diseases and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine preparation for treating intractable skin diseases and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 10-50 parts of paper mulberry leaves, 10-50 parts of rhizoma smilacis glabrae, 10-30 parts of euphorbia cordifolia, 10-30 parts of trichosanthes kirilowii roots, 10-30 parts of spina gleditsiae and 3-5 parts of liquorice. The traditional Chinese medicine preparation is specially used for treating (conditioning) intractable skin diseases such as eczema, psoriasis (psoriasis), allergic dermatitis, lupus erythematosus and the like, is high in cure rate and small in side effect, and solves the problem that no medicine can treat the intractable skin diseases in the world.

Description

Technical Field

[0001] The present invention relates to the field of pharmaceutical technology, and particularly to a traditional Chinese medicine preparation for treating intractable skin diseases and a preparation method thereof. Background Art

[0002] Skin diseases refer to diseases occurring in the skin, mucous membranes and their appendages, which are caused by various reasons, such as physical and chemical factors, pathogen infections, endocrine and metabolic factors, immunogenicity and degenerative changes, etc. Common skin diseases include eczema, psoriasis (psoriasis vulgaris), allergic dermatitis, lupus erythematosus, etc. Common symptoms of skin diseases include itching, pain, numbness and systemic symptoms, such as chill, fever, fatigue, loss of appetite and joint pain, etc., bringing great pain and inconvenience to patients.

[0003] Patients with intractable skin diseases such as eczema, psoriasis (psoriasis vulgaris), allergic dermatitis, lupus erythematosus, etc. have a wide population and are difficult to treat, and are called the "cancer that does not kill". These patients either suffer from pain or intolerable itching, and they are in great pain every day.

[0004] Currently, the only effective drugs for treating these intractable skin diseases in the world are hormonal drugs and biological agents. However, these western medicines have poor curative effects, can only relieve but not cure, and have strong side effects. Summary of the Invention

[0005] The purpose of the present invention is to provide a traditional Chinese medicine preparation for treating intractable skin diseases and a preparation method thereof in view of the deficiencies of the prior art, so as to solve the problems raised in the background art.

[0006] To achieve the above purpose, the present invention provides the following technical solutions:

[0007] A traditional Chinese medicine preparation for treating intractable skin diseases,

[0008] which is composed of the following raw materials in parts by weight: Broussonetia papyrifera leaves 10 - 50 parts, Smilax glabra 10 - 50 parts, Setaria viridis roots 10 - 30 parts, Bryonia dioica roots 10 - 30 parts, Gleditsia sinensis thorns 10 - 30 parts, Glycyrrhiza uralensis 3 - 5 parts.

[0009] Preferably, the traditional Chinese medicine preparation is composed of the following raw materials in parts by weight: Broussonetia papyrifera leaves 37 parts, Smilax glabra 25 parts, Setaria viridis roots 11 parts, Bryonia dioica roots 12 parts, Gleditsia sinensis thorns 11 parts, Glycyrrhiza uralensis 4 parts.

[0010] Preferably, the traditional Chinese medicine preparation is composed of the following raw materials in parts by weight: Broussonetia papyrifera leaves 22 parts, Smilax glabra 36 parts, Setaria viridis roots 17 parts, Bryonia dioica roots 10 parts, Gleditsia sinensis thorns 12 parts, Glycyrrhiza uralensis 3 parts.

[0011] The present invention further provides a preparation method of the traditional Chinese medicine preparation for treating intractable skin diseases, and the method comprises the following steps:

[0012] Step 1) Select Broussonetia papyrifera leaves (alias: Broussonetia kazinoki leaves), Smilax glabra, Setaria viridis roots, wild gourd roots, Gleditsia sinensis thorns, and licorice according to a certain proportion. After washing, soak them for about 5 hours.

[0013] Step 2) Extract the medicinal materials.

[0014] Step 3) Concentrate the medicinal liquid.

[0015] Step 4) Fill the concentrated medicinal liquid into bottles, with the bottle capacity being 100 ML.

[0016] Step 5) Sterilize the filled preparation at high temperature.

[0017] Step 6) Detect the product.

[0018] Step 7) Pack the qualified products into boxes and store them in the warehouse.

[0019] The treatment (conditioning) scope of the bottled traditional Chinese medicine preparation of the present invention: eczema, psoriasis (psoriasis vulgaris), allergic dermatitis, lupus erythematosus, dermatomyositis.

[0020] Dosage and administration: One bottle each in the morning, noon, and evening for adults, and 1 - 2 bottles per day for those with a body weight below 50 kg.

[0021] Treatment (conditioning) duration: Generally three months.

[0022] Compared with the problems of being difficult to cure and having large side effects in the prior art, the traditional Chinese medicine preparation of the present invention can effectively treat (condition) intractable skin diseases such as eczema, psoriasis (psoriasis vulgaris), allergic dermatitis, and lupus erythematosus. It has a high cure rate and small side effects, solving the dilemma of no effective medicine for these intractable skin diseases in the world. Detailed implementation mode

[0023] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in combination with the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0024] Embodiment 1

[0025] The traditional Chinese medicine preparation for treating intractable skin diseases is composed of the following raw materials in parts by weight:

[0026] 10 - 50 parts of Broussonetia papyrifera leaves, 10 - 50 parts of Smilax glabra, 10 - 30 parts of Setaria viridis roots, 10 - 30 parts of wild gourd roots, 10 - 30 parts of Gleditsia sinensis thorns, and 3 - 5 parts of licorice.

[0027] Specifically, the traditional Chinese medicine preparation is composed of the following raw materials in parts by weight: 37 parts of Broussonetia papyrifera leaves, 25 parts of Smilax glabra, 11 parts of Setaria viridis roots, 12 parts of wild bottle gourd roots, 11 parts of Gleditsia sinensis thorns, and 4 parts of liquorice.

[0028] Example 2

[0029] The traditional Chinese medicine preparation for treating intractable skin diseases is composed of the following raw materials in parts by weight:

[0030] 22 parts of Broussonetia papyrifera leaves, 36 parts of Smilax glabra, 17 parts of Setaria viridis roots, 10 parts of wild bottle gourd roots, 12 parts of Gleditsia sinensis thorns, and 3 parts of liquorice.

[0031] Example 3

[0032] The preparation method of the traditional Chinese medicine preparation for treating intractable skin diseases includes the following steps:

[0033] Step 1) Weigh out Broussonetia papyrifera leaves (alias Broussonetia papyrifera leaves), Smilax glabra, Setaria viridis roots, wild bottle gourd roots, Gleditsia sinensis thorns, and liquorice according to the weight ratio in Example 1 or 2, wash them and soak for about 5 hours;

[0034] Step 2) Quench the medicinal materials;

[0035] Step 3) Concentrate the medicinal liquid;

[0036] Step 4) Pour the concentrated medicinal liquid into bottles, and the bottle capacity is 100 ML;

[0037] Step 5) Sterilize the filled preparation at high temperature;

[0038] Step 6) Detect the product;

[0039] Step 7) Pack the qualified products into boxes and store them in the warehouse.

[0040] Dosage and administration: Adults take one bottle each in the morning, middle, and evening every day. Those with a body weight below 50 kg take 1-2 bottles per day.

[0041] Treatment (conditioning) duration: Generally three months.

[0042] Possible side effects: 1. A very small number of patients may have mild abdominal pain and diarrhea after taking the medicine; 2. If a very small number of patients take an overdose of the medicine, it may cause neuralgia in the parotid region, and the symptoms will stop after reducing the dose or stopping the medicine for two or three days.

[0043] Efficacy evaluation criteria:

[0044] Cured: The skin has completely healed, the itching has completely disappeared, the skin has become smooth and elastic, and all other corresponding symptoms have disappeared. The patient has returned to a normal life and does not relapse after recovery.

[0045] Effective: The erythema, scales and infiltration degree of the skin are significantly improved, the area of skin lesions is reduced, and other corresponding symptoms start to improve.

[0046] Ineffective: After applying the ointment prepared in the embodiment of the present invention externally, all symptoms do not improve.

[0047] Clinical observation, cured cases:

[0048] 1. Yuan XX, male, 74 years old, from Suizhou City, Hubei Province. Suffering from chronic eczema for 30 years, cured in 3 months;

[0049] 2. Fan XX, male, 18 years old, from Xiangyang City, Hubei Province. Suffering from erythrodermic psoriasis for 5 years, cured in 3 months;

[0050] 3. Zhou XX, male, 70 years old, from Xi'an City, Shaanxi Province. Suffering from guttate psoriasis for 30 years, cured in 3 months;

[0051] 4. Zhang XX, male, 30 years old, from Changsha City, Hunan Province. Suffering from chronic eczema for 20 years, cured in 3 months;

[0052] 5. Liu XX, male, 45 years old, from Tianhe District, Guangzhou City. Suffering from psoriasis for 20 years, cured in 3 months;

[0053] 6. Li XX, female, 50 years old, from Panyu District, Guangzhou City. Suffering from psoriasis for 8 years, cured in 1 month;

[0054] 7. Gao Gui, male, 62 years old, from Huaiji County, Guangdong Province. Suffering from tinea manuum et pedis for 10 years, cured in 3 hours;

[0055] 8. Huang Min, female, 58 years old, from Xiangyang City, Hubei Province. Suffering from pustular psoriasis for 5 years, cured in 6 months;

[0056] 9. Yang Juan, female, 40 years old, from Xiangyang City, Hubei Province. Suffering from allergic dermatitis for 5 years, cured in 3 months;

[0057] 10. Lin Shangxing, female, 45 years old, from Tianhe District, Guangzhou City. Suffering from tinea pedis for 2 years, cured in 3 hours;

[0058] 11. Yang Wei, female, 40 years old, from Foshan City, Guangdong Province. Suffering from chronic eczema for 3 years, cured in 3 months;

[0059] 12. Cheng Xianping, male, 63 years old, from Suizhou City, Hubei Province. Suffering from tinea corporis for 5 years, cured in 1 week;

[0060] 13. Li Liangming, male, 33 years old, from Xiangyang City, Hubei Province. Suffering from chronic eczema for 3 years, cured in 3 months;

[0061] 14. Guo Jianbing, male, 40 years old, from Foshan City, Guangdong Province. Suffering from erythrodermic psoriasis for 20 years, cured in 8 months;

[0062] 15. Zhou Jiankai, male, 23 years old, from Tianhe District, Guangzhou. Suffered from pustular psoriasis for 1 year and was cured in 2 months.

[0063] 16. Dai Yi, male, 86 years old, from Tianhe District, Guangzhou. Suffered from pudendal eczema for 10 years and was cured in 3 months.

[0064] 17. Guo Pingli, female, 50 years old, from Wuhan City, Hubei Province. Suffered from chronic eczema for 8 years and was cured in 3 months.

[0065] 18. Xiao Yaowei, female, 38 years old, from Yuexiu District, Guangzhou. Suffered from allergic dermatitis for 3 years and was cured in 3 months.

[0066] 19. Deng Haiwen, male, 48 years old, from Yuexiu District, Guangzhou. Suffered from early-stage skin cancer for 1 year and was cured in 1 week.

[0067] 20. Lin Xiasheng, male, 75 years old, from Yongzhou City, Hunan Province. Suffered from chronic eczema for 40 years and was cured in 3 months.

[0068] 21. Li Changnv, 5 years old, from Nansha District, Guangzhou. Suffered from chronic eczema for 1 year and was cured in 3 months.

[0069] 22. Wang Fang, female, 30 years old, from Nansha District, Guangzhou. Suffered from chronic eczema for 5 years and was cured in 3 months.

[0070] After nearly two decades of unremitting efforts, repeated clinical trials and improvements, the inventors finally developed a traditional Chinese medicine preparation for the special treatment (regulation) of intractable skin diseases such as eczema, psoriasis (psoriasis vulgaris), allergic dermatitis, and lupus erythematosus, solving the worldwide dilemma of having no effective drugs for these intractable skin diseases.

[0071] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A traditional Chinese medicine preparation for treating intractable skin diseases, characterized in that: The traditional Chinese medicine preparation is composed of the following raw materials in parts by weight: 10-50 parts of Broussonetia papyrifera leaves, 10-50 parts of Smilax glabra, 10-30 parts of Setaria viridis roots, 10-30 parts of wild bottle gourd roots, 10-30 parts of Gleditsia sinensis thorns, and 3-5 parts of liquorice.

2. The traditional Chinese medicine preparation for treating intractable skin diseases according to claim 1, wherein: The traditional Chinese medicine preparation is composed of the following raw materials in parts by weight: 37 parts of Broussonetia papyrifera leaves, 25 parts of Smilax glabra, 11 parts of Setaria viridis roots, 12 parts of wild bottle gourd roots, 11 parts of Gleditsia sinensis thorns, and 4 parts of liquorice.

3. The traditional Chinese medicine preparation for treating intractable skin diseases according to claim 1, wherein: The traditional Chinese medicine preparation is composed of the following raw materials in parts by weight: 22 parts of Broussonetia papyrifera leaves, 36 parts of Smilax glabra, 17 parts of Setaria viridis roots, 10 parts of wild bottle gourd roots, 12 parts of Gleditsia sinensis thorns, and 3 parts of liquorice.

4. A preparation method of a traditional Chinese medicine preparation for treating intractable skin diseases, characterized in that: It includes the following steps: Step 1) Select Broussonetia papyrifera leaves (alias: Broussonetia papyrifera leaves), Smilax glabra, Setaria viridis roots, wild bottle gourd roots, Gleditsia sinensis thorns, and liquorice according to the proportion, wash them and soak for about 5 hours; Step 2) Extract the medicinal materials; Step 3) Concentrate the medicinal liquid; Step 4) Fill the concentrated medicinal liquid into bottles; Step 5) Sterilize the filled preparation at high temperature; Step 6) Detect the product; Step 7) Pack the qualified products into boxes and store them in the warehouse.

5. The preparation method of a traditional Chinese medicine preparation for treating intractable skin diseases according to claim 4, characterized in that: The capacity of filling into bottles in Step 4 is 100 ML.