Medicine sterile grinding and mixing device for oncology department

Abstract

The medicine sterile grinding and mixing device for the oncology department comprises a mixing bin, a mounting support is fixedly connected to the bottom end of the mixing bin, and an auxiliary mixing mechanism is arranged on the outer side of the mixing bin; by means of the arranged auxiliary mixing mechanism, when a user puts medicine into a mixing bin through a feeding pipe, the user can start a grinding and mixing device to grind the medicine, in the grinding process, the user can start a motor, the output end of the motor drives a rotating rod to rotate, the rotating rod drives an extrusion plate to rotate, the extrusion plate is oval, and therefore the medicine can be ground through the auxiliary mixing mechanism. An extrusion plate can randomly extrude a limiting plate to move, the limiting plate can drive a transmission rod to move, the transmission rod can drive a knocking plate to knock on a rubber plate, and the acting force of the knocking plate on the rubber plate is transmitted to the inner wall of the mixing bin to cause vibration, so that medicine particles adhered to the inner wall of the mixing bin are effectively knocked off; and the mixing and grinding uniformity of the medicines is remarkably improved, the medicines are fully mixed in the preparation process, and non-uniform component distribution is avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of drug mixing, and particularly to a sterile grinding and mixing device for oncology drugs. Background Art

[0002] The preparation of oncology drugs usually involves requirements of high precision, high safety and a sterile environment. Oncology drugs are dose-sensitive in treatment, posing extremely high requirements for the size of drug particles, mixing uniformity and guarantee of a sterile environment.

[0003] The prior art discloses a patent for invention with the application number CN115090194B, which discloses a sterile grinding and mixing device for oncology drugs. Its basic description is as follows: The ground drugs are likely to adhere to the existing device, affecting their discharge and collection. The powder ground by the existing device is mixed with bacteria, and patients are prone to getting sick if they take it directly for a long time. A sterile grinding and mixing device for oncology drugs includes a housing. A filler sterilization mechanism is provided on the housing. A power mechanism is provided on the housing through a circular guard plate. A drug grinding mechanism is provided inside the housing. An auxiliary grinding mechanism is provided on the drug grinding mechanism. A shaking discharge mechanism is provided at the lower end of the housing. A drug collection mechanism is installed below the shaking discharge mechanism. The present invention sterilizes and mixes the drugs through the filler sterilization mechanism, avoiding patients from taking drugs carrying bacteria. The drug grinding mechanism realizes reciprocating grinding of the drugs. The shaking discharge mechanism and the auxiliary discharge mechanism cooperate to discharge all the powder, avoiding powder residue in the device. The drug collection mechanism realizes the storage of the powder in a sterile environment.

[0004] In the actual implementation process, there are still some problems: During the drug grinding process of traditional devices, the particles in the mixing chamber are prone to adhering to the inner wall of the equipment, resulting in uneven grinding and mixing, affecting the homogeneity and dosage accuracy of the drugs. The sealing performance of traditional equipment is insufficient, and it cannot effectively isolate external pollution sources, easily leading to drug contamination by microorganisms or bacteria. Summary of the Invention

[0005] (I) Technical Problems to be Solved In order to solve the above problems of the prior art, the present invention provides a sterile grinding and mixing device for oncology drugs, which solves the problems of easy wall adhesion, uneven mixing, insufficient sealing and easy contamination of traditional devices.

[0006] (II) Technical Solutions In order to achieve the above object, the main technical solution adopted by the present invention is as follows: A sterile grinding and mixing device for oncology drugs, comprising a mixing chamber. The bottom end of the mixing chamber is fixedly connected with a mounting bracket. An auxiliary mixing mechanism is arranged outside the mixing chamber. The auxiliary mixing mechanism includes a connecting plate, a motor, a partition plate, a rubber plate, a knocking plate, a transmission rod, a return spring, a limiting plate, a perforation, an extrusion plate and a rotating rod. A perforation is formed in the middle of the partition plate. The inner wall of the perforation is slidably connected with the transmission rod. One end of the transmission rod is fixedly connected with the knocking plate. A return spring is sleeved on the middle of the transmission rod; A sealing mechanism is arranged outside the mixing chamber. The sealing mechanism includes a buckle, an electric push rod, a sealing plate, a connecting rod, a locking handle and a gas alarm. The electric push rod is rotatably connected to the front of the sealing plate. The connecting rod is fixedly connected to the front of the sealing plate. A gas alarm is arranged on one side of the sealing plate.

[0007] A rubber plate is fixedly connected to one side wall of the mixing chamber. The knocking plate is attached to the outside of the rubber plate. A grinding and mixing mechanism is connected to the inner wall of the mixing chamber.

[0008] The connecting plate is fixedly connected to the outside of the mounting bracket. The partition plate is fixedly connected to the inside of the mounting bracket.

[0009] The other end of the transmission rod is fixedly connected with a limiting plate. One end of the return spring is fixedly connected to the inside of the limiting plate. The other end of the return spring is fixedly connected to the inside of the partition plate.

[0010] A rotating rod is rotatably connected to the inner wall of the connecting plate. An extrusion plate is fixedly connected to the middle of the rotating rod. The outside of the extrusion plate is attached to the outside of the limiting plate.

[0011] Two feeding pipes are fixedly connected to the top end of the mixing chamber. A support plate is fixedly connected to one side wall of the connecting plate.

[0012] The support plate is fixedly connected with a motor at the top end. The output end of the motor penetrates through the connecting plate and is fixedly connected with one end of the rotating rod.

[0013] The sealing plate is hinged to the outer wall of the mixing chamber. One end of the electric push rod is rotatably connected to the outer wall of the mixing chamber.

[0014] The gas alarm is fixedly connected to the outer wall of the mixing chamber.

[0015] Two buckles are fixedly connected to the front of the sealing plate. Two locking handles are fixedly connected to the outer wall of the mixing chamber. The locking handle is snap-fitted with the buckle.

[0016] (III) Beneficial effects The beneficial effects of the present invention are as follows: Through the provided auxiliary mixing mechanism, when the user puts the drug into the interior of the mixing chamber through the feeding pipe, the user can start the grinding and mixing device to grind the drug. During the grinding process, the user can start the motor, the output end of the motor drives the rotating rod to rotate, the rotating rod drives the pressing plate to rotate. The pressing plate is oval, and the pressing plate can randomly press the limiting plate to move. The limiting plate can drive the transmission rod to move, and the transmission rod can drive the knocking plate to knock on the rubber plate. The acting force of the knocking plate on the rubber plate is transmitted to the inner wall of the mixing chamber to cause vibration, thereby effectively knocking off the drug particles adhering to the inner wall of the mixing chamber, significantly improving the mixing and grinding uniformity of the drug, ensuring the full mixing of the drug during the preparation process, avoiding uneven distribution of components, and cooperating with the provided sealing mechanism, which can effectively isolate external pollution sources, ensure the sterility of the operating environment, and prevent the drug from being contaminated by bacteria or microorganisms. The gas alarm can monitor the gas state in the device in real time. Once harmful gas leakage is detected, it can issue an alarm in time to protect the health of the operator. The design of the buckle and the locking handle ensures the sealing reliability and prevents the leakage of drugs or volatile components. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 is a schematic structural diagram of the present invention; Figure 2 is a schematic structural diagram of the front side of the present invention; Figure 3 is a schematic structural diagram of the mixing chamber part of the present invention; Figure 4 of the present invention Figure 2 enlarged view of part A; Figure 5 is a schematic structural diagram of the reset spring part of the present invention.

[0018]

DESCRIPTION OF THE REFERENCE NUMERALS

[0019] In order to better explain the present invention for easy understanding, the present invention will be described in detail below with reference to the accompanying drawings through specific embodiments.

[0020] Please refer to Figures 1 to 5As shown in the figure, a sterile grinding and mixing device for oncology drugs of the present invention includes a mixing chamber 1. A mounting bracket 2 is fixedly connected to the bottom end of the mixing chamber 1. An auxiliary mixing mechanism 4 is provided outside the mixing chamber 1. The auxiliary mixing mechanism 4 includes a connecting plate 401, a motor 402, a partition plate 403, a rubber plate 404, a knocking plate 405, a transmission rod 406, a return spring 407, a limiting plate 408, a through hole 409, a pressing plate 410 and a rotating rod 411. A through hole 409 is opened in the middle of the partition plate 403. The inner wall of the through hole 409 is slidably connected with a transmission rod 406. One end of the transmission rod 406 is fixedly connected with a knocking plate 405. A return spring 407 is sleeved on the middle part of the transmission rod 406; A sealing mechanism 3 is provided outside the mixing chamber 1. The sealing mechanism 3 includes a buckle 301, an electric push rod 302, a sealing plate 303, a connecting rod 304, a locking handle 305 and a gas alarm 306. An electric push rod 302 is rotatably connected to the front surface of the sealing plate 303. A connecting rod 304 is fixedly connected to the front surface of the sealing plate 303. A gas alarm 306 is provided on one side of the sealing plate 303. In the actual implementation process, through the provided auxiliary mixing mechanism 4, when the user puts the drug into the interior of the mixing chamber 1 through the feeding pipe 5, the user can start the grinding and mixing device to grind the drug. During the grinding process, the user can start the motor 402. The output end of the motor 402 drives the rotating rod 411 to rotate, and the rotating rod 411 drives the pressing plate 410 to rotate. The pressing plate 410 is elliptical, and the pressing plate 410 can randomly press the limiting plate 408 to move. The limiting plate 408 can drive the transmission rod 406 to move, and the transmission rod 406 can drive the knocking plate 405 to knock on the rubber plate 404. The acting force of the knocking plate 405 on the rubber plate 404 is transmitted to the inner wall of the mixing chamber 1 to cause vibration, thereby effectively knocking off the drug particles adhering to the inner wall of the mixing chamber 1, significantly improving the mixing and grinding uniformity of the drug, ensuring the full mixing of the drug during the preparation process, avoiding uneven distribution of components, and cooperating with the provided sealing mechanism 3, which can effectively isolate external pollution sources, ensure the sterility of the operating environment, avoid the drug being contaminated by bacteria or microorganisms. The gas alarm 306 can monitor the gas state in the device in real time. Once harmful gas leakage is detected, it can issue an alarm in time to protect the health of the operator. The designs of the buckle 301 and the locking handle 305 ensure the sealing reliability and avoid the leakage of drugs or volatile components.

[0021] Optionally, a rubber plate 404 is fixedly connected to one side wall of the mixing chamber 1, a knocking plate 405 is attached to the outer side of the rubber plate 404, and the inner wall of the mixing chamber 1 is connected to the grinding and mixing mechanism 6. In actual implementation, the knocking plate 405 connected to the other end of the transmission rod 406 contacts the rubber plate 404. When the knocking plate 405 quickly knocks the rubber plate 404, the knocking force is transmitted to the inner wall of the mixing chamber 1 through the rubber plate 404, causing the inner wall of the mixing chamber 1 to vibrate, which can effectively loosen or knock off drug particles adhering to the inner wall, preventing drug accumulation or adhesion. Tumor drugs have extremely high requirements for dosage and uniformity, because slight dosage deviations may affect the efficacy of the drug or increase toxic side effects. In addition, tumor drugs are usually expensive. The vibration mechanism of the device can promptly knock off drug particles adhering to the inner wall of the mixing chamber 1, avoiding drug waste and improving the utilization rate of raw materials.

[0022] Optionally, connecting plate 401 is fixedly connected to the outside of mounting bracket 2, and blocking plate 403 is fixedly connected to the inside of mounting bracket 2. In actual implementation, this provides a stable support structure for the installation of internal components. The design of mounting bracket 2 separates the device's external support from its internal functional components, ensuring that each component operates independently and without interference. The combination of connecting plate 401 and mounting bracket 2 enhances the overall mechanical strength of the device, ensuring stability during high-intensity grinding and mixing processes, and preventing shaking or component displacement caused by vibration or handling.

[0023] Optionally, the other end of the transmission rod 406 is fixedly connected to a limit plate 408, and one end of a return spring 407 is fixedly connected to the inner side of the limit plate 408, while the other end of the return spring 407 is fixedly connected to the inner side of the blocking plate 403. In actual implementation, one end of the return spring 407 is fixedly connected to the inner side of the limit plate 408, and the other end is fixedly connected to the inner side of the blocking plate 403. This design allows the transmission rod 406 to move flexibly after being subjected to force and quickly return to its initial position under the action of the return spring 407. The limit plate 408 drives the transmission rod 406 in a specific direction, causing the knocking plate 405 to complete the knocking action. After the knocking action is completed, the return spring 407 generates a pulling force, returning the limit plate 408 and the transmission rod 406 to their original positions, preparing for the next knocking action. The provision of the return spring 407 ensures the continuity and accuracy of the movement of the transmission rod 406, while also preventing damage to the equipment due to excessive movement.

[0024] Optionally, a rotating rod 411 is rotatably connected to the inner wall of the connecting plate 401. A pressing plate 410 is fixedly connected to the middle of the rotating rod 411, and the outer side of the pressing plate 410 is attached to the outer side of the limiting plate 408. During actual implementation, a rotating rod 411 is rotatably connected to the inner wall of the connecting plate 401, and an oval pressing plate 410 is fixedly connected to the middle of the rotating rod 411. The outer side of the pressing plate 410 is attached to the outer side of the limiting plate 408. When the motor 402 is started, the motor 402 drives the rotating rod 411 to rotate, and the rotating rod 411 drives the pressing plate 410 to rotate accordingly. Since the pressing plate 410 is oval in design, it exerts irregular pressure on the limiting plate 408 during rotation, forcing the limiting plate 408 to move reciprocally. The movement of the limiting plate 408 further drives the transmission rod 406 to slide up and down, driving the knocking plate 405 to periodically knock the rubber plate 404.

[0025] Optionally, two feeding pipes 5 are fixedly connected to the top end of the mixing bin 1, and a support plate 7 is fixedly connected to one side wall of the connecting plate 401. During actual implementation, two feeding pipes 5 are fixedly connected to the top end of the mixing bin 1 for separately feeding different types or components of drug raw materials into the mixing bin 1. The arrangement of the two feeding pipes 5 can achieve step-by-step feeding of multi-component drugs, facilitating precise control of the drug ratio and improving the uniformity of drug mixing.

[0026] Optionally, a motor 402 is fixedly connected to the top end of the support plate 7. The output end of the motor 402 penetrates through the connecting plate 401 and is fixedly connected to one end of the rotating rod 411. During actual implementation, a motor 402 is fixedly connected to the top end of the support plate 7. The output end of the motor 402 passes through the connecting plate 401 and is fixedly connected to one end of the rotating rod 411. After the motor 402 is started, the output end drives the rotating rod 411 to perform a rotational motion. The rotation of the rotating rod 411 further drives the pressing plate 410 connected thereto to move, thereby applying force to the limiting plate 408 through the pressing plate 410, triggering the reciprocal movement of the limiting plate 408 and the transmission rod 406, and finally realizing the dynamic knocking function of the knocking plate 405. The support plate 7 provides a stable support structure to ensure the stability and working accuracy of the motor 402 during high-speed operation.

[0027] Optionally, the sealing plate 303 is hinged to the outer wall of the mixing bin 1, and one end of the electric push rod 302 is rotatably connected to the outer wall of the mixing bin 1. In the actual implementation process, the sealing plate 303 is hinged to the outer wall of the mixing bin 1 to form an openable sealing interface with the mixing bin 1. One end of the sealing plate 303 is connected by a hinge and can be freely opened and closed; the other end is controlled by the electric push rod 302. One end of the electric push rod 302 is connected to the sealing plate 303, and the other end is rotatably connected to the outer wall of the mixing bin 1. During operation, after receiving an instruction, the electric push rod 302 makes a telescopic movement to drive the sealing plate 303 to achieve precise opening and closing. During drug feeding or cleaning, the electric push rod 302 retracts to open the sealing plate 303, facilitating the operator to feed materials or clean the equipment.

[0028] Optionally, the gas alarm 306 is fixedly connected to the outer wall of the mixing bin 1. In the actual implementation process, the gas alarm 306 is fixedly connected to the outer wall of the mixing bin 1, and the gas inside the mixing bin 1 is monitored in real time through its built-in sensor. When there is abnormal gas (such as toxic, irritating gas or abnormal air pressure) in the mixing bin 1, the gas alarm 306 will immediately detect and give an audible and visual alarm to prompt the operator to take safety measures in a timely manner. The position of the gas alarm 306 is fixed on the outer wall of the mixing bin 1, which can ensure that it is adjacent to the mixing area, thereby improving the sensitivity and accuracy of monitoring.

[0029] Optionally, two buckles 301 are fixedly connected to the front surface of the sealing plate 303, and two locking handles 305 are fixedly connected to the outer wall of the mixing bin 1. The locking handles 305 are snap-connected to the buckles 301. In the actual implementation process, two buckles 301 are fixedly connected to the front surface of the sealing plate 303, while the locking handles 305 are fixedly connected to the outer wall of the mixing bin 1. A snap-connection design is adopted between the buckles 301 and the locking handles 305. When the sealing plate 303 is closed, the buckles 301 are inserted and tightly snap-connected to the locking handles 305 to form a firm sealing interface.

[0030] The above shows and describes the basic principles, main features and advantages of the present invention. Moreover, the standard parts used in the present invention can all be purchased from the market. The special-shaped parts can be customized according to the records in the specification and the drawings. The specific connection methods of each part all adopt conventional means such as bolts, rivets, welding, etc. that are mature in the prior art. The machinery, parts and equipment all adopt conventional models in the prior art, and the circuit connection adopts the conventional connection method in the prior art, which will not be elaborated here.

[0031] The above are only the embodiments of the present invention, and thus do not limit the patent scope of the present invention. Any equivalent transformation made by using the content of the specification and drawings of the present invention, or directly or indirectly applied in the relevant technical fields, shall be equally included in the patent protection scope of the present invention.

Claims

1. A sterile grinding and mixing device for oncology drugs, comprising a mixing chamber (1), characterized in that: The bottom end of the mixing bin (1) is fixedly connected with a mounting bracket (2). An auxiliary mixing mechanism (4) is arranged outside the mixing bin (1). The auxiliary mixing mechanism (4) includes a connecting plate (401), a motor (402), a partition plate (403), a rubber plate (404), a knocking plate (405), a transmission rod (406), a return spring (407), a limiting plate (408), a through hole (409), a pressing plate (410) and a rotating rod (411). A through hole (409) is formed in the middle of the partition plate (403). The inner wall of the through hole (409) is slidably connected with a transmission rod (406). One end of the transmission rod (406) is fixedly connected with a knocking plate (405). A return spring (407) is sleeved in the middle of the transmission rod (406). A sealing mechanism (3) is arranged outside the mixing bin (1). The sealing mechanism (3) includes a buckle (301), an electric push rod (302), a sealing plate (303), a connecting rod (304), a locking handle (305) and a gas alarm (306). The electric push rod (302) is rotatably connected to the front surface of the sealing plate (303). The connecting rod (304) is fixedly connected to the front surface of the sealing plate (303). A gas alarm (306) is arranged on one side of the sealing plate (303).

2. The aseptic grinding and mixing device for oncology drugs according to claim 1, wherein: A rubber plate (404) is fixedly connected to one side wall of the mixing bin (1). The knocking plate (405) is attached to the outside of the rubber plate (404). A grinding and mixing mechanism (6) is connected to the inner wall of the mixing bin (1).

3. The aseptic grinding and mixing device for oncology drugs according to claim 1, characterized in that: The connecting plate (401) is fixedly connected to the outside of the mounting bracket (2). The partition plate (403) is fixedly connected to the inside of the mounting bracket (2).

4. A sterile grinding and mixing device for oncology drugs according to claim 1, wherein: The other end of the transmission rod (406) is fixedly connected with a limiting plate (408). One end of the return spring (407) is fixedly connected to the inside of the limiting plate (408). The other end of the return spring (407) is fixedly connected to the inside of the partition plate (403).

5. A sterile grinding and mixing device for oncology drugs according to claim 1, characterized in that: A rotating rod (411) is rotatably connected to the inner wall of the connecting plate (401). A pressing plate (410) is fixedly connected to the middle of the rotating rod (411). The outside of the pressing plate (410) is attached to the outside of the limiting plate (408).

6. The aseptic grinding and mixing device for oncology drugs according to claim 1, wherein: Two feeding pipes (5) are fixedly connected to the top end of the mixing bin (1). A support plate (7) is fixedly connected to one side wall of the connecting plate (401).

7. The aseptic grinding and mixing device for oncology drugs according to claim 6, characterized in that: A motor (402) is fixedly connected to the top end of the support plate (7). The output end of the motor (402) penetrates through the connecting plate (401) and is fixedly connected to one end of the rotating rod (411).

8. A sterile grinding and mixing device for oncology drugs according to claim 1, characterized in that: The sealing plate (303) is hinged to the outer wall of the mixing bin (1). One end of the electric push rod (302) is rotatably connected to the outer wall of the mixing bin (1).

9. A sterile grinding and mixing device for oncology drugs according to claim 1, characterized in that: The gas alarm (306) is fixedly connected to the outer wall of the mixing bin (1).

10. A sterile grinding and mixing device for oncology drugs according to claim 1, characterized in that: Two buckles (301) are fixedly connected to the front surface of the sealing plate (303), and two locking handles (305) are fixedly connected to the outer wall of the mixing bin (1). The locking handle (305) is engaged with the buckle (301).

Images