Application device and analyte monitoring system

Abstract

The present disclosure describes an application device and an analyte monitoring system, the application device comprising a first housing, a second housing, a drive mechanism, a moving body, a piercing member disposed on the moving body, and a proximal end proximate to a host and a distal end remote from the host during operation, the first shell and the second shell move relatively in a mutually approaching mode to release the movement body, and the movement body moves towards the near end together with the puncture component under the action of the driving mechanism after being released so as to apply the monitoring device to the host and is at least partially located under the skin of the host. According to the present disclosure, it is possible to provide an application device and an analyte monitoring system which are convenient to operate and can accurately apply a monitoring device to a host.

Description

Technical Field

[0001] The present disclosure generally relates to the field of medical devices, and particularly to an application device and an analyte monitoring system. Background Art

[0002] Currently, the ways for diabetic patients to self-monitor blood glucose mainly include traditional finger-prick blood testing (Blood Glucose Monitoring, BGM) and continuous glucose monitoring system (Continuous Glucose Monitoring System, CGMS). Among them, CGMS can detect the blood glucose level of patients in real time and has the ability to detect occult hyperglycemia and hypoglycemia that are not easily detected by traditional finger-prick blood testing methods, becoming a new trend in blood glucose monitoring.

[0003] CGMS usually uses a glucose sensor that can be inserted under the skin and can react with glucose in interstitial fluid, and an electronic device that is applied to the skin and connected to the glucose sensor to monitor the glucose concentration in interstitial fluid. In order to insert the glucose sensor under the skin and apply the electronic device to the skin, an insertion device is usually required. Specifically, the insertion device may include a needle that can pierce the skin. The glucose sensor is inserted under the skin through the needle, and then the needle is separated from the glucose sensor and removed from the skin.

[0004] However, in the above-mentioned prior art, the process of piercing the skin or removing the needle from the skin usually requires manual driving. In this case, since it may be difficult to precisely control factors such as the force for driving the needle, the position where the needle pierces the skin, the depth at which the needle penetrates under the skin, or the timing of removing the needle from the skin, on the one hand, it may affect the user experience when inserting the glucose sensor, and on the other hand, it may also result in low accuracy of the obtained glucose concentration due to the glucose sensor not being inserted into the desired position. Summary of the Invention

[0005] In view of the above-mentioned prior art situation, the present disclosure is completed, and its purpose is to provide an application device and an analyte monitoring system that are easy to operate and can accurately apply the monitoring device to the host.

[0006] To this end, the present disclosure provides an application device for applying a monitoring device to a host. The application device includes a first housing, a second housing, a driving mechanism, a moving body, a puncturing member provided on the moving body, and a proximal end that approaches the host and a distal end that is away from the host during operation. The first housing includes a first holding portion that releasably holds the moving body. The second housing has a proximal surface that contacts the skin of the host during operation. The moving body includes a receiving portion that houses the monitoring device. The puncturing member is configured to at least partially introduce the monitoring device into the subcutaneous tissue of the host. The first housing and the second housing move relative to each other in a manner of approaching each other to release the holding of the moving body by the first holding portion. After the moving body is released, under the action of the driving mechanism, the moving body and the puncturing member move together toward the proximal end to apply the monitoring device to the host and at least partially locate it under the skin of the host.

[0007] In the present disclosure, the application device includes a moving body for accommodating a monitoring device, a puncturing member that can at least partially introduce the monitoring device into the subcutaneous tissue of the host, a first housing that releasably holds the moving body, and a second housing that can cooperate with the first housing to release the locking of the moving body by the first housing (even if the first holding portion releases the moving body, this action can be simply referred to as unlocking). After unlocking, the moving body and the puncturing member can move toward the proximal end close to the host under the action of the driving mechanism to apply the monitoring device to the surface of the host, and the puncturing member can at least partially introduce the monitoring device into the subcutaneous tissue of the host. In this case, by placing the proximal surface of the second housing on the skin of the host, on the one hand, it is convenient to apply force to relatively move the two housings (the first housing and the second housing) to unlock the moving body, and on the other hand, it helps to define the application position, and through the driving mechanism, a relatively precise driving effect can be provided, so that the puncturing force and puncturing depth of the puncturing member during application can be more accurately controlled. Therefore, it is beneficial to accurately apply the monitoring device to the host.

[0008] In addition, according to the application device involved in the present disclosure, optionally, the moving body includes a first locking portion configured to be releasably interlocked with the first holding portion, and the second housing includes a first triggering portion that can separate the first holding portion from the first locking portion to release the moving body. Thus, the moving body can be releasably held in the first holding portion through the cooperation of the first locking portion and the first holding portion, and the first triggering portion facilitates the release of the moving body through the relative movement of the two housings.

[0009] In addition, according to the application device involved in the present disclosure, optionally, when the first housing and the second housing move relative to each other along the central axis direction of the application device, the first triggering portion acts on the first locking portion to separate the first locking portion from the first holding portion. In this case, by moving the two housings relative to each other along the central axis direction, the first locking portion can be separated from the first holding portion through the first triggering portion, which is convenient for the operator to use.

[0010] In addition, according to the application device involved in the present disclosure, optionally, the first holding portion is a convex structure formed on the inner wall of the first housing. When the moving body is held by the first holding portion, the first locking portion engages with the convex structure; the first triggering portion deflects the first locking portion in a direction away from the first holding portion to separate the first locking portion from the first holding portion. In this case, compared with arranging a first holding portion with a certain length that can be offset inside the first housing, arranging the first holding portion as a convex structure formed on the inner wall of the first housing can reduce the manufacturing process difficulty of the first housing and the space required for arranging the first holding portion, thereby contributing to the miniaturization of the application device and being convenient for the operator to use.

[0011] In addition, according to the application device involved in the present disclosure, optionally, the first housing includes a first limiting portion configured to inhibit the second housing from detaching from the first housing, and the second housing includes a first restricted portion that is coupled to the first limiting portion. In this case, the second housing can be restricted by the first housing through the cooperation of the first restricted portion and the first limiting portion, and inhibiting the second housing from detaching from the first housing can contribute to improving the reliability of the application device.

[0012] In addition, according to the application device involved in the present disclosure, optionally, the first housing includes a second limiting portion configured to inhibit the movement of the second housing toward the proximal end. After the first housing and the second housing move relative to each other to release the moving body, the second housing is restricted by the second limiting portion. In this case, the movement of the second housing toward the proximal end can be restricted through the second limiting portion, thereby inhibiting the operator from reusing the application device and reducing the risk of the used puncturing member that has not been disinfected again coming into contact with the host.

[0013] In addition, according to the application device involved in the present disclosure, optionally, the first limiting portion and the second limiting portion are arranged adjacent to each other along the central axis direction of the application device, and the first restricted portion is configured to cooperate with the second limiting portion to hold the second housing. Thereby, it can contribute to simplifying the structure of the application device.

[0014] In addition, according to the application device involved in the present disclosure, optionally, the driving mechanism includes a first driving part and a second driving part, the moving body includes a second holding part that releasably holds the puncturing member, after the moving body and the puncturing member move towards the proximal end to a predetermined position under the action of the first driving part, the second holding part releases the puncturing member, and the puncturing member moves towards the distal end under the action of the second driving part. In this case, by performing the two operations of application and retraction respectively by the first driving part and the second driving part, the puncturing force, puncturing depth, and the timing of leaving the host of the puncturing member can be controlled more accurately.

[0015] In addition, according to the application device involved in the present disclosure, optionally, the first driving part is an elastic element, and both ends of the first driving part are respectively abutted against the first housing and the moving body. When the moving body is held in the first holding part, the first driving part is in a compressed state. In this case, when the moving body is released, the first driving part in the compressed state can automatically apply a force to the moving body to achieve automatic pushing, which is convenient for the operator to use.

[0016] In addition, according to the application device involved in the present disclosure, optionally, the second driving part is an elastic element, and both ends of the second driving part are respectively abutted against the moving body and the puncturing member. When the puncturing member is held in the second holding part, the second driving part is in a compressed state. In this case, when the puncturing member is released, the second driving part in the compressed state can automatically apply a force to the puncturing member to achieve automatic retraction of the puncturing member, which is convenient for the operator to use.

[0017] In addition, according to the application device involved in the present disclosure, optionally, the application device includes an applicator cap, the applicator cap is detachably assembled to the first housing, and when the applicator cap is assembled to the first housing, the second housing is located in the sealed accommodation space formed by the applicator cap and the first housing. In this case, a sealed space can be formed through the cooperation of the applicator cap and the first housing to protect the internal structure, and the second housing located in the sealed space can prevent unwanted accidental touches from occurring, improving the reliability of the application device.

[0018] In addition, according to the application device related to the present disclosure, optionally, the monitoring device includes a sensor that can be partially placed under the skin of the host, an electronic component coupled to the sensor, and a sealing component that seals the sensor. The applicator cap is coupled to the sealing component. When the applicator cap is removed from the first housing, the sealing component is removed together with the applicator cap so that the application device forms an applicable state. In this case, the sealing component that seals the sensor can help maintain the aseptic state of the sensor for a long time. By coupling the applicator cap with the sealing component and being able to remove the sealing component simultaneously when removing the applicator cap, it is convenient for the operator to use.

[0019] In addition, according to the application device related to the present disclosure, optionally, the sealing component has a first engaging feature, and the applicator cap includes a second engaging feature. The first engaging feature cooperates with the second engaging feature so that when the applicator cap rotates in a first direction, the sealing component rotates following the applicator cap, and when the applicator cap rotates in a second direction opposite to the first direction, the sealing component does not move. In this case, the sealing component can be removed while the applicator cap is rotated in the first direction to remove the applicator cap, thus facilitating use; and during the assembly process of assembling the applicator cap to the first housing by rotating the applicator cap in the second direction opposite to the first direction, the sealing state of the sealing component will not be affected, thus facilitating the factory assembly of the application device and the monitoring device.

[0020] The second aspect of the present disclosure provides an analyte monitoring system, including the application device described in the first aspect of the present disclosure and a monitoring device. Thus, an analyte monitoring system that is easy to operate and can accurately apply the monitoring device to the host can be provided.

[0021] According to the present disclosure, an application device and an analyte monitoring system that are easy to operate and can accurately apply the monitoring device to the host can be provided. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Embodiments of the present disclosure will now be further explained in detail only by way of examples referring to the drawings.

[0023] Figure 1 is a schematic diagram of an application scenario of the monitoring device involved in the example of the present disclosure.

[0024] Figure 2 is a schematic diagram of the monitoring device involved in the example of the present disclosure.

[0025] Figure 3 is a schematic diagram of the sensor involved in the example of the present disclosure.

[0026] Figure 4It is a schematic diagram showing the sterilization component related to the examples of the present disclosure.

[0027] Figure 5 It is an exploded view showing the sterilization component related to the examples of the present disclosure.

[0028] Figure 6A It is a schematic diagram showing the sterilization component and the electronic component before assembly related to the examples of the present disclosure.

[0029] Figure 6B It is a schematic diagram showing the sterilization component and the electronic component after assembly related to the examples of the present disclosure.

[0030] Figure 7 It is a schematic diagram showing the overall appearance of the application device related to the examples of the present disclosure.

[0031] Figure 8 It is a sectional view showing the application device related to the examples of the present disclosure.

[0032] Figure 9 It is an exploded view showing the application device related to the examples of the present disclosure.

[0033] Figure 10 It is a schematic diagram showing the first housing related to the examples of the present disclosure.

[0034] Figure 11 It is a schematic diagram showing the second housing related to the examples of the present disclosure. <>

[0035] Figure 12 It is a schematic diagram showing the moving body related to the examples of the present disclosure.

[0036] Figure 13 It is a sectional schematic diagram showing the first housing, the second housing and the moving body after assembly related to the examples of the present disclosure.

[0037] Figure 14 It is a sectional schematic diagram showing the first locking portion before being triggered by the first triggering portion related to the examples of the present disclosure.

[0038] Figure 15 It is a sectional schematic diagram showing the first locking portion after being triggered by the first triggering portion related to the examples of the present disclosure.

[0039] Figure 16 It is a sectional schematic diagram showing the first restricted portion not engaged with the second restricting portion related to the examples of the present disclosure.

[0040] Figure 17 It is a sectional schematic diagram showing the first restricted portion engaged with the second restricting portion related to the examples of the present disclosure.

[0041] [[ID=[]59]] Figure 181 is a schematic diagram showing an exploded view of the moving body and the piercing member involved in the example of the present disclosure from a first perspective.

[0042] Figure 19 1 is a schematic diagram showing an exploded view of the moving body and the piercing member according to the example of the present disclosure from a second perspective.

[0043] Figure 20 1 is a schematic cross-sectional view showing a puncture member according to an example of the present disclosure when being retained.

[0044] Figure 21 is a schematic diagram illustrating a seal assembly and an applicator cap according to an example of the present disclosure.

[0045] Figure 22 Schematic diagram showing the structure of the inclined groove involved in the example of the present disclosure. DETAILED DESCRIPTION

[0046] The preferred embodiments of the present disclosure are described in detail below with reference to the accompanying drawings. In the following description, identical components are assigned identical reference numerals, and duplicate descriptions are omitted. In addition, the accompanying drawings are merely schematic, and the proportions of the dimensions of the components and the shapes of the components may differ from the actual ones.

[0047] It should be noted that the terms "including" and "having" and any variations thereof in this disclosure, such as a process, method, system, product or device that includes or has a series of steps or units, are not necessarily limited to those steps or units clearly listed, but may include or have other steps or units that are not clearly listed or are inherent to these processes, methods, products or devices.

[0048] The present disclosure relates to an application device that can be used to apply a monitoring device to a host, such as applying the monitoring device to the host's body surface or placing the monitoring device completely or partially subcutaneously. The application device of this embodiment can facilitate application of the monitoring device to a desired location. In the present disclosure, the monitoring device can be used to monitor physiological parameters of the host. The monitoring device can also be other medical devices that need to be applied to the host.

[0049] The application device involved in this embodiment may also be called an insertion device, a pushing device, a boosting device, a transport device, an implantation device, an application device, or an auxiliary device, etc. It should be noted that each name is used to indicate the device involved in this embodiment for applying the monitoring device to the host and should not be understood as limiting.

[0050] In addition, the present disclosure also provides an analyte monitoring system. The analyte monitoring system of the present disclosure may include a monitoring device and an application device. The monitoring device can be used to obtain physiological parameter information of a host. The monitoring device can be applied to the host through the application device, and the physiological parameter information of the host can be monitored through the monitoring device. In the present disclosure, the analyte monitoring system may also be referred to as an analyte monitoring kit, an analyte combination kit, a monitoring system, etc.

[0051] Hereinafter, in conjunction with the drawings, the application device and the analyte monitoring system involved in the present disclosure will be described and explained.

[0052] Figure 1 It is a diagram showing an application scenario of the monitoring device 800 involved in an example of the present disclosure.

[0053] In some examples, the monitoring device 800 can be applied to a host via the application device 100 and applied to a desired position, and the host can obtain physiological parameter information (which can be simply referred to as physiological information) through the monitoring device 800 applied to itself.

[0054] In some examples, the analyte monitoring system 1000 may include a monitoring device 800 and an application device 100 (see Figure 1 ). The monitoring device 800 can be used to obtain physiological parameter information of a host. The monitoring device 800 can be applied to the host through the application device 100, and the physiological parameter information of the host can be monitored through the monitoring device 800.

[0055] In some examples, the analyte monitoring system 1000 may further include a reading device 900 communicatively connected to the monitoring device 800 (see Figure 1 ). The monitoring device 800 applied to the host can transmit the obtained physiological parameter information to the reading device 900, for example, wirelessly, thereby facilitating the host to read and monitor its own physiological parameter information.

[0056] In some examples, the monitoring device 800 can be an analyte sensor device, which can generate information on specific analytes in body fluids based on body fluids, for example, react with analytes in body fluids and generate analyte information. In this case, by reacting the sensor 8 with analytes in body fluids, it is possible to facilitate the acquisition of analyte information in body fluids.

[0057] In some examples, the analyte can be one or more of glucose, acetylcholine, amylase, bilirubin, cholesterol, chorionic gonadotropin, creatine kinase, creatine, creatinine, DNA, fructosamine, glucose, glutamine, growth hormone, ketone bodies, lactate, oxygen, peroxide, prostate-specific antigen, prothrombin, RNA, thyroid-stimulating hormone, or troponin.

[0058] For ease of understanding, the monitoring device 800 of the present disclosure will be described first. Hereinafter, taking glucose as an analyte as an example, the monitoring device 800 related to the examples of the present embodiment will be described. It should be noted that for other analytes, those skilled in the art can analyze other analytes with a slight modification to the monitoring device 800 used for glucose.

[0059] Figure 2 It is a schematic diagram showing the monitoring device 800 related to the examples of the present disclosure. Figure 3 It is a schematic diagram showing the sensor 8 related to the examples of the present disclosure.

[0060] In some examples, the monitoring device 800 may include a sensor 8 and an electronic component 9 (see Figure 2 ). The sensor 8 can be assembled to the electronic component 9. For the convenience of reacting with tissue fluid such as body fluid, for example, the sensor 8 can be partially or completely placed under the skin of the host. After the sensor 8 is placed under the skin, it can react with glucose in the subcutaneous tissue fluid to generate glucose information of the host. The electronic component 9 can be applied to the body surface of the host. The electronic component 9 can be electrically connected to the sensor 8 and receive the glucose information generated by the sensor 8. In addition, the electronic component 9 can also provide the electric energy required for the sensor 8 to obtain physiological information. Thus, it is beneficial for the sensor 8 to continuously monitor under the skin of the host.

[0061] In some examples, the sensor 8 may include an implant part 81 and a connection part 82 (see Figure 3 ). The implant part 81 can be placed under the skin of the host and connected to the electronic component 9 through the connection part 82. In this case, by placing the implant part 81 under the skin of the host and connecting the implant part 81 to the electronic component 9 through the connection part 82, it is convenient to temporarily fix the sensor 8 at a specific part of the host.

[0062] In some examples, the implant part 81 may include a working electrode and a counter electrode. In the present embodiment, a sensing layer including glucose oxidase may be provided on the working electrode. The sensor 8 placed under the skin can undergo an oxidation-reduction reaction with glucose in the tissue fluid or blood through the glucose oxidase on the working electrode, and form a circuit with the counter electrode to generate a current signal, and the current signal is analyzed and processed to obtain glucose concentration information. The current signal generated by the sensor 8 can be transmitted to the electronic component 9.

[0063] In some examples, the implant portion 81 may further include a reference electrode. The reference electrode may form a known and fixed potential difference with the tissue fluid or blood. In this case, the potential difference between the working electrode and the tissue fluid or blood can be measured based on the potential difference formed between the reference electrode and the working electrode. Thus, the voltage generated by the working electrode can be obtained more accurately. Additionally, in this case, the electronic component 9 can automatically adjust and maintain the voltage stability at the working electrode according to a preset voltage value, so that the measured current signal can more accurately reflect the glucose concentration information in the tissue fluid or blood. In some examples, the number of reference electrodes can be one or more, such as two.

[0064] In some examples, the electronic component 9 may include a housing 91 (see Figure 2 ). In some examples, the electronic component 9 may include electronic devices disposed inside the housing 91. In some examples, the electronic devices may include a power supply module, a switch module, and a processing module. The power supply module can supply power to the sensor 8 and / or the processing module, the switch module can control the connection and disconnection between the power supply module and the sensor 8 and / or the processing module, and the processing module can process the signals (such as glucose information) generated by the sensor 8.

[0065] In some examples, the electronic devices may have an initial mode configured to be an open circuit and a working mode configured to be a closed circuit. In this case, when the electronic devices are in the initial mode, they are configured to be an open circuit, thereby saving power before the electronic devices enter the working state. In some examples, when the electronic devices are configured to be in the initial mode, the switch module may be in an off state, and when the electronic devices are configured to be in the working mode, the switch module may be in a closed state. That is, the electronic devices can be switched from the initial mode to the working mode through the switch module. In this case, by controlling the switch module to switch the electronic devices from the initial mode to the working mode, the power consumption before the electronic devices work can be effectively reduced.

[0066] In some examples, the electronic component 9 can be configured to be excited from the initial mode to the working mode by magnetic action or light action. In this case, the electronic component 9 is excited from the initial mode to the working mode through non-contact components such as magnetic action or light action, which can contribute to the miniaturization of the electronic component 9.

[0067] In some examples, the application device 100 (described later) may include a magnet. In some examples, when the monitoring device 800 has not been applied to the host, since the electronic component 9 of the monitoring device 800 is close to the magnet at this time, the switching module of the electronic component 9 may be in an open state. In some examples, when the monitoring device 800 is applied to the host, since the electronic component 9 of the monitoring device 800 is away from the magnet at this time, the switching module of the electronic component 9 may be excited to a closed state. In this case, in the standby state after the analyte monitoring system 1000 is manufactured and before it is used, the monitoring device 800 is located within the application device 100, and at this time, the monitoring device 800 may be in an initial mode of low power consumption or zero power consumption, which helps to extend the standby life (also referred to as shelf life) of the monitoring device 800.

[0068] In some examples, when the monitoring device 800 is applied to the host and the application device 100 has not left the host, since the electronic component 9 of the monitoring device 800 is close to the magnet at this time, the switching module of the electronic component 9 may be in an open state. In some examples, when the monitoring device 800 is applied to the host and the application device 100 has left the host, since the electronic component 9 of the monitoring device 800 is away from the magnet at this time, the switching module of the electronic component 9 may be excited to a closed state.

[0069] Figure 4 is a schematic diagram showing the sterilization component 92 involved in the examples of the present disclosure. Figure 5 is an exploded view showing the sterilization component 92 involved in the examples of the present disclosure. Figure 6A is a schematic diagram showing the sterilization component 92 and the electronic component 9 before assembly in the examples of the present disclosure. Figure 6B is a schematic diagram showing the sterilization component 92 and the electronic component 9 after assembly in the examples of the present disclosure. In Figure 5 and Figure 6A the line JK schematically represents the central axis of the sterilization component 92.

[0070] In some examples, the sensor 8 can be sealed first, the sterilization component 92 containing the sensor 8 can be sterilized, and then the sterilization component 92 can be assembled to the electronic component 9 and then assembled with the application device 100. In this case, compared with the prior art in which the sensor 8 and the electronic component 9 need to be sterilized separately, and the operator also needs to pick up and assemble the sensor 8 located in other containers with the application device 100 containing the electronic component 9 before use to form a complete monitoring device 800, the application device 100 of the present disclosure can accommodate the complete monitoring device 800, and the operator does not need to perform additional pick-up and assembly actions before use. It is convenient for the operator to use.

[0071] In the present disclosure, there are various embodiments for sealing the sensor 8. Hereinafter, one of the embodiments for sealing the sensor 8 will be introduced, but the specific structure is not limited thereto.

[0072] In some examples, the monitoring device 800 may include a sealing component 93 (see Figure 4 ). The sealing component 93 can be used to seal the sensor 8. Specifically, the sealing component 93 can seal the implanted portion 81 of the sensor 8. In this case, the sealing component 93 that seals the sensor 8 can help maintain the aseptic state of the sensor 8 for a long time, thereby increasing the standby life of the monitoring device 800 (the standby life refers to the duration from when the monitoring device 800 is sterilized and assembled and leaves the factory to before the operator uses it, and can also be referred to as the shelf life).

[0073] In some examples, the sensor 8 can be sterilized, kept in the sealing component 93, then the sensor 8 and the sealing component 93 are assembled onto the electronic component 9 to form the monitoring device 800, and then the monitoring device 800 is installed into the application device 100. That is to say, the sealing component 93 can be part of the sterilization component 92. Before using the application device 100 to apply the monitoring device 800 to the host, the sealing component 93 can be removed first to make the monitoring device 800 in an applicable state. In this case, compared with the prior art where the sensor 8 needs to be separately packaged and sterilized from the electronic component 9, and the operator also needs to pick up the sensor 8 in another container before use and assemble it with the electronic component 9 to form a complete monitoring device 800, the application device 100 of the present disclosure can accommodate the complete monitoring device 800, and the operator does not need to perform additional picking and assembling actions before use. It is convenient for the operator to use.

[0074] In some examples, the monitoring device 800 may include a mounting base 94 (see Figure 4 ). The sensor 8 can be assembled with the electronic component 9 through the mounting base 94. In some examples, the mounting base 94 may have a first through hole 941 (see Figure 5 ). The first through hole 941 can serve as a channel for the sensor 8 to extend outwards. In some examples, one end of the sensor 8 can pass through the side wall of the mounting base 94. Specifically, the connecting portion 82 of the sensor 8 can pass through the side wall of the mounting base 94. In some examples, the electronic component 9 may include an electrical connection base. After the sensor 8 is assembled with the electronic component 9 through the mounting base 94, the sensor 8 can be electrically connected to the electronic devices inside the electronic component 9 through the electrical connection base.

[0075] In some examples, the sealing assembly 93 can cooperate with the mounting base 94 to seal the sensor 8. Specifically, the implanted portion 81 of the sensor 8 can extend out of the mounting base 94, and the sealing assembly 93 can abut against the mounting base 94 and surround the outer periphery of the implanted portion 81 of the sensor 8 that extends out of the mounting base 94. That is to say, the sealing assembly 93 can seal one end of the first through hole 941.

[0076] In some examples, the application device 100 can include a puncturing member 40 (see Figure 4 and Figure 5 ). The puncturing member 40 can be configured to at least partially introduce the monitoring device 800 into the host's subcutaneous tissue. For example, the puncturing member 40 can introduce the implanted portion 81 of the sensor 8 into the host's subcutaneous tissue. In some examples, the puncturing member 40 can include a needle portion 41 and a carrying portion 42 connected to the needle portion 41 (see Figure 5 ). The needle portion 41 can accommodate the sensor 8. In some examples, the sealing assembly 93, the mounting base 94, and the puncturing member 40 can cooperate to seal the sensor 8 (the specific structure of the puncturing member 40 will be described in detail later, and here mainly introduce the content related to sealing the sensor 8). Specifically, the first through hole 941 of the mounting base 94 can serve as a channel for the puncturing member 40 to penetrate downward. The carrying portion 42 of the puncturing member 40 abuts against the upper surface of the mounting base 94, seals the upper end of the first through hole 941. The needle portion 41 passes through the first through hole 941 and penetrates downward to accommodate the implanted portion 81 of the sensor 8. The sealing assembly 93 surrounds the outer periphery of the needle portion 41 and the portion of the sensor 8 that extends out of the mounting base 94. At this time, the puncturing member 40 and the sealing assembly 93 respectively seal both ends of the first through hole 941, thereby sealing the sensor 8 in the sealing space formed by the cooperation and connection of the puncturing member 40, the mounting base 94, and the sealing assembly 93. In some examples, the carrying portion 42 can also penetrate downward from the first through hole 941, and the sealing assembly 93 can be detachably connected to the carrying portion 42.

[0077] In some examples, the sterilization assembly 92 can further include a seal. For example, the sterilization assembly 92 can include a first seal 951 and a second seal 952 (see Figure 5 ). Among them, the first seal 951 can be located between the carrying portion 42 and the upper surface of the mounting base 94. This can help improve the sealing performance of the sterilization assembly 92. The second seal 952 can be located between the sealing assembly 93 and the lower surface of the mounting base 94. This can help improve the sealing performance of the sterilization assembly 92.

[0078] In some examples, the sterilization assembly 92 including the mounting base 94, the sealing assembly 93, the puncturing member 40, and the sensor 8 can be sterilized, and then the sterilization assembly 92 can be assembled to the electronic component 9 and then assembled with the application device 100. SeeFigure 6A The sterilization component 92 can be assembled to the electronic component 9 along the D1 direction to form a Figure 6B An assembly comprising a monitoring device 800 is shown which may be mounted to an application device 100 .

[0079] In the present disclosure, the sealing of the sensor 8 may also include other variations. For example, in some examples, the housing 91 of the electronic component 9 may include an upper housing 911 and a lower housing 912 (see FIG. Figure 2 The electronic components can be disposed within the housing formed by the upper housing 911 and the lower housing 912. In some examples, the mounting base 94 can be the upper housing 911 or the lower housing 912 of the electronic assembly 9 and can cooperate with the sealing assembly 93 and the piercing member 40 to seal the sensor 8. The specific structure can be obtained by slightly modifying the mounting base 94 described above and will not be further described here.

[0080] In some examples, the electronic component 9 can be adhered to the host's body surface. For example, the monitoring device 800 can further include an adhesive sheet disposed at the bottom of the housing 91 of the electronic component 9 and having adhesive properties. The electronic component 9 can be adhered to the host's body surface via the adhesive sheet.

[0081] In some examples, the electronic assembly 9 can be configured to communicate with an external device via wireless or wired communication. In this case, by configuring the electronic assembly 9 to communicate with the external device, the analyte information acquired by the sensor 8 can be read in real time or on a scheduled basis. The external device can be a reader 900.

[0082] In some examples, monitoring device 800 can be communicatively connected to reader device 900. In some examples, reader device 900 can be a display with communication capabilities. In some examples, the communication capabilities of reader device 900 can be implemented via wireless or wired communication. Wireless communication methods can include Bluetooth, NFC, Wi-Fi, etc. Wired communication methods can include USB, fiber optics, etc. Alternatively, reader device 900 can be a smart terminal installed with an application compatible with monitoring device 800. The smart terminal can be a laptop, tablet, smartphone, etc.

[0083] As described above, the monitoring device 800 of the present disclosure may be applied to a host via the application device 100. Hereinafter, the application device 100 of the present disclosure will be described in detail with reference to the accompanying drawings.

[0084] Figure 7 1 is a schematic diagram showing the overall appearance of an application device 100 according to an example of the present disclosure. Figure 8 1 is a cross-sectional view showing an application device 100 according to an example of the present disclosure. Figure 9FIG. 0 is an exploded view showing the application device 100 involved in the examples of the present disclosure. In Figure 8 and Figure 9 , the line CA schematically represents the central axis CA of the application device 100. Whenever "central axis CA" appears hereinafter, it refers to the central axis CA of the application device 100.

[0085] In some examples, the application device 100 may include a first housing 10 that provides a moving space, and a moving body 20 (see in combination with Figure 7 , Figure 8 and Figure 9 ). The moving body 20 can accommodate the monitoring device 800 and is configured to move within the moving space of the first housing 10. In some examples, the application device 100 may have a proximal end 101 that is close to the host during operation and a distal end 102 that is far from the host (see Figure 8 ). It can be understood that in this article, the "proximal end 101" can be understood as the end that is close to the host during operation, and the "distal end 102" can be understood as the end that is far from the host during operation.

[0086] In some examples, the moving body 20 can be releasably held in the first housing 10. When the moving body 20 is released, it can move within the moving space of the first housing 10.

[0087] In some examples, the application device 100 may include a second housing 30 (see Figure 8 or Figure 9 ). The second housing 30 can move relative to the first housing 10. In some examples, the second housing 30 can be at least partially located within the accommodation space of the first housing 10. In some examples, a moving space can be formed after the first housing 10 and the second housing 30 are assembled and combined. The moving body 20 can move within the moving space formed after the first housing 10 and the second housing 30 are assembled and combined.

[0088] In some examples, the second housing 30 can limit the moving path of the moving body 20. That is, when the moving body 20 is released, it can move along the moving path defined by the second housing 30. In some examples, the axis of the first housing 10 and the axis of the second housing 30 can be substantially parallel to the central axis CA of the application device 100. In some examples, the first housing 10 and the second housing 30 can be coaxially arranged. For example, in Figure 8 , the axes of the first housing 10 and the second housing 30 can overlap with the central axis CA of the application device 100.

[0089] In some examples, the second housing 30 and the first housing 10 can move relative to each other to release the moving body 20. In this case, the cooperation of the two housings can unlock the moving body 20, which is convenient for the operator to use. In some examples, the second housing 30 can define the application position of the monitoring device 800 on the body surface of the host. In some examples, the second housing 30 can have a proximal surface 31 that contacts the host's skin during operation (see Figure 9 ). In this case, by placing the proximal surface 31 of the second housing 30 on the host's skin, on the one hand, it is convenient to apply force to make the first housing 10 and the second housing 30 move relative to each other (hereinafter simply referred to as the relative movement of the two housings) to unlock the moving body 20, and on the other hand, it helps to define the application position, which is beneficial to accurately apply the monitoring device 800 to the host. Moreover, the application device 100 of the present disclosure can place the proximal surface 31 of the second housing 30 on the host's skin to apply force. Compared with the application device provided with a trigger button on the housing, the force application area is larger, and the operator can use it more conveniently through the linkage trigger of the two housings.

[0090] In some examples, the moving body 20 can include a receiving portion 21 (see Figure 9 ). The receiving portion 21 can be used to accommodate the monitoring device 800. In some examples, the monitoring device 800 can be releasably held in the receiving portion 21. In this case, by driving the moving body 20, the monitoring device 800 can be moved together. After the monitoring device 800 is applied to the host, the monitoring device 800 can be detached from the receiving portion 21 to be left on the host for monitoring.

[0091] In some examples, the monitoring device 800 applied to the host can stay on the host by detaching from the holding of the moving body 20. Thus, the monitoring device 800 applied to the host can monitor the physiological parameters of the host. In some examples, the monitoring device 800 applied to the host can adhere to the body surface of the host. When the operator moves the application device 100 away from the body surface of the host, at this time, the monitoring device 800 can adhere to the body surface of the host and detach from the receiving portion 21.

[0092] In some examples, as described above, the application device 100 can include a puncturing member 40 (see Figure 8 or Figure 9 ). The puncturing member 40 can partially introduce the monitoring device 800 into the subcutaneous tissue of the host. In some examples, the puncturing member 40 can be provided on the moving body 20. When the moving body 20 moves toward the proximal end 101 after being released, the puncturing member 40 and the receiving portion 21 provided on the moving body 20 also move toward the proximal end 101 to apply the monitoring device 800 accommodated in the receiving portion 21 to the host, and the puncturing member 40 can place at least a part of the monitoring device 800 under the skin of the host.

[0093] In some examples, the puncturing member 40 can be releasably disposed on the moving body 20. When the puncturing member 40 is released, it can move relative to the moving body 20. For example, when the puncturing member 40 is released, it can move away from the host relative to the moving body 20. Thus, the puncturing member 40 can be separated from the host.

[0094] In some examples, the applying device 100 can include a driving mechanism 50 (see Figure 8 ). After the moving body 20 is released, it can move together with the puncturing member 40 toward the proximal end 101 under the action of the driving mechanism 50 to apply the monitoring device 800 to the host and at least partially locate it under the skin of the host. In this case, the driving mechanism 50 can provide a driving effect relatively precisely, so that the puncturing force and puncturing depth of the puncturing member 40 during the applying process can be controlled more accurately. Thus, it is beneficial to accurately apply the monitoring device 800 to the host.

[0095] In some examples, the driving mechanism 50 can include a first driving part 51 (see Figure 9 ). The first driving part 51 can be configured to drive the moving body 20. In some examples, the first driving part 51 can act on the moving body 20 in a direction toward the proximal end 101. When the moving body 20 is released, the moving body 20 can be driven by the first driving part 51 toward the proximal end 101 to push the monitoring device 800 accommodated in the accommodating part 21 toward the host.

[0096] In other examples, the applying device 100 may not include the first driving part 51 either. In this case, when the moving body 20 is released, the moving body 20 can also be manually driven to move toward the proximal end 101.

[0097] In some examples, the driving mechanism 50 can include a second driving part 52 (see ' ). The second driving part 52 can be configured to drive the puncturing member 40. In some examples, the second driving part 52 can act on the puncturing member 40 in a direction toward the distal end 102. When the puncturing member 40 is released, the puncturing member 40 can move toward the distal end 102 under the action of the second driving part 52 to make the puncturing member 40 leave the host. In this case, the retraction operation of the puncturing member 40 by the second driving part 52 can more accurately control the timing of the puncturing member 40 leaving the host.

[0098] In some other examples, the application device 100 may also not include the second driving part 52. In this case, the puncturing member 40 can be manually driven away from the host. For example, in some examples, the puncturing member 40 may also be integrally connected to the moving body 20, and the puncturing member 40 is moved away from the host by manually moving the moving body 20 in a direction away from the host.

[0099] In some examples, the application device 100 may include a transmission mechanism 7 (see Figure 9 ). In some examples, the transmission mechanism 7 may abut against one end of the moving body 20 facing the distal end 102, and both ends of the first driving part 51 may respectively abut against the transmission mechanism 7 and the first housing 10. In this case, the first driving part 51 can apply an acting force towards the proximal end 101 to the moving body 20 through the transmission mechanism 7. In some examples, the transmission mechanism 7 may accommodate the puncturing member 40 that moves towards the distal end 102 after being released. In this case, the transmission mechanism 7 can help the puncturing member 40 that has moved towards the distal end 102 to be stably held inside the first housing 10.

[0100] Figure 8 is a schematic diagram showing the first housing 10 involved in the examples of the present disclosure. Figure 10 is a schematic diagram showing the second housing 30 involved in the examples of the present disclosure. Figure 11 is a schematic diagram showing the moving body 20 involved in the examples of the present disclosure. Figure 12 is a schematic cross-sectional view showing the assembly of the first housing 10, the second housing 30, and the moving body 20 involved in the examples of the present disclosure.

[0101] In some examples, one or more ribbed protrusions 11 extending substantially along the direction of the central axis CA may be provided on the inner wall of the first housing 10 (see Figure 13 ). In some examples, the ribbed protrusions 11 can be used as reinforcing ribs to effectively improve the anti-deformation ability of the first housing 10. In some examples, the ribbed protrusions 11 can also be used as guiding ribs to facilitate the assembly of the first housing 10 and the second housing 30. Among them, the guiding ribs can also help to inhibit the undesired rotation of the second housing 30 within the first housing 10.

[0102] In some examples, a male-female mechanical mating structure may be provided on the inner wall of the first housing 10 and the outer wall of the second housing 30. In some examples, the male-female mechanical mating structure may be a concave-convex mating structure. For example, in some examples, one or more ribbed protrusions 11 may be provided on the inner wall of the first housing 10, and one or more ribbed grooves 32 may be provided on the outer wall of the second housing 30 (see Figure 10 and Figure 10)。In some examples, when the second housing 30 is assembled to the first housing 10, one or more ribbed protrusions 11 of the first housing 10 can be respectively inserted into one or more ribbed grooves 32 of the second housing 30. In this case, on the one hand, through the matching of the ribbed protrusions 11 and the ribbed grooves 32, the assembly of the first housing 10 and the second housing 30 can be facilitated; on the other hand, through the ribbed protrusions 11 and the ribbed grooves 32, the direction of relative movement between the first housing 10 and the second housing 30 can also be guided; in addition, through the cooperation of the ribbed protrusions 11 and the ribbed grooves 32, it can also help to suppress the undesired rotation of the second housing 30. In some examples, the plurality of ribbed protrusions 11 provided on the inner wall of the first housing 10 can be evenly or symmetrically distributed on the inner wall of the first housing 10.

[0103] In some examples, a recessed structure can be formed in the ribbed protrusions 11 provided on the inner wall of the first housing 10, and a protruding structure can be formed in the ribbed grooves 32 provided on the outer wall of the second housing 30. When the second housing 30 is assembled to the first housing 10, the ribbed protrusions 11 of the first housing 10 can be located in the ribbed grooves 32 of the second housing 30, and the protruding structure in the ribbed grooves 32 can be located in the recessed structure in the ribbed protrusions 11. Thus, it can be beneficial to further improve the assembly stability of the first housing 10 and the second housing 30; and it can further define the guiding path, which helps to perform more precise direction guiding when the first housing 10 and the second housing 30 move relative to each other.

[0104] In some examples, as described above, the moving body 20 can be releasably held by the first housing 10. In some examples, the first housing 10 can include a first holding portion 12 (see Figure 11 ). The first holding portion 12 can be configured to releasably hold the moving body 20. In some examples, the first holding portion 12 can be provided on the inner wall of the first housing 10. For example, in some examples, the first holding portion 12 can be a convex structure formed on the inner wall of the first housing 10.

[0105] In some examples, the moving body 20 can include a first locking portion 23 (see Figure 10 ). Among them, the first locking portion 23 can be configured to be releasably interlocked with the first holding portion 12. Thus, the moving body 20 can be releasably held by the first holding portion 12 through the cooperation of the first locking portion 23 and the first holding portion 12. In some examples, the moving body 20 can include a side wall 22. In some examples, the first locking portion 23 can be provided on the side wall 22 of the moving body 20.

[0106] In some examples, the interlock between the first holding portion 12 and the held member can be achieved by at least one of a buckle, a hook, a latch, or a pin. For example, in some examples, the interlock between the first holding portion 12 and the first locking portion 23 can be achieved by at least one of a buckle, a hook, a latch, or a pin. In this case, the first holding portion 12 and the first locking portion 23 are releasably interlocked by at least one of a buckle, a hook, a latch, or a pin, thereby providing an interlock method that is easy to release.

[0107] In some examples, as described above, the first holding portion 12 can be a convex structure formed on the inner wall of the first housing 10 (see Figure 12 ). In some examples, when the moving body 20 is held by the first holding portion 12, the first locking portion 23 engages with the convex structure. The first locking portion 23 can be deflected away from the first holding portion 12 to separate the first locking portion 23 from the first holding portion 12. Since in general, in order to enable the target member to be offset, it is usually achieved by adjusting the material or the structure, such as using a soft material to prepare the target member or by providing a target member with a certain length, such a target member can be offset under the action of an external force. In the present disclosure, in order to enable the first housing 10 to protect the internal structure, a relatively hard material is usually used to prepare the first housing 10. In this case, compared with providing a first holding portion 12 with a certain length that can be offset inside the first housing 10, setting the first holding portion 12 as a convex structure formed on the inner wall of the first housing 10 can reduce the manufacturing process difficulty of the first housing 10 and reduce the space required for providing the first holding portion 12, thereby contributing to the miniaturization of the application device 100 and facilitating the operator's use.

[0108] In some examples, the first holding portion 12 can have a surface facing the distal end 102, and the first locking portion 23 can have a surface facing the proximal end 101. When the moving body 20 is held, the surface of the first holding portion 12 facing the distal end 102 and the surface of the first locking portion 23 facing the proximal end 101 can be engaged with each other. In some examples, when the moving body 20 is released, the surface of the first holding portion 12 facing the distal end 102 and the surface of the first locking portion 23 facing the proximal end 101 can be separated from each other.

[0109] In some examples, the first locking portion 23 can include an arm 230 extending generally along the direction of the central axis CA (hereinafter referred to as the first arm 230 for ease of reading), and a protrusion 231 that is linked to the first arm 230 and protrudes away from the central axis CA generally in a direction orthogonal to the central axis CA (hereinafter referred to as the first protrusion 231 for ease of reading) (see Figure 10)。In some examples, the first arm 230 may be formed on the side wall 22 of the moving body 20. In this case, when the first protrusion 231 of the first locking portion 23 abuts against the first holding portion 12, by actuating the first protrusion 231 to move towards the central axis CA, the first protrusion 231 no longer abuts against the first holding portion 12 (i.e., the first locking portion 23 is separated from the first holding portion 12), whereby the first locking portion 23 can be conveniently released from the first holding portion 12.

[0110] In some examples, the first arm 230 may be elastic. In some examples, the first arm 230 may be elastic in a direction substantially orthogonal to the central axis CA. In some examples, the first arm 230 may tend to expand away from the central axis CA in the direction from the proximal end 101 to the distal end 102. That is, in the natural state (i.e., the state without external force), compared with the end of the first arm 230 near the proximal end 101 and the end of the first arm 230 near the distal end 102, the distance between the end of the first arm 230 near the proximal end 101 and the central axis CA is closer. In some other examples, the first arm 230 may also be substantially parallel to the central axis CA. In some examples, when an action is applied to the first arm 230 in a direction substantially orthogonal to the central axis CA, the first arm 230 may pivot. For example, when an action is applied to the first arm 230 in a direction substantially orthogonal to the central axis CA and towards the central axis CA, the first arm 230 may deflect, causing the end of the first arm 230 near the distal end 102 to move towards the central axis CA. Thereby, the moving body 20 can be released simply and conveniently.

[0111] In some examples, the first arm 230 may expand away from the central axis CA in the direction from the proximal end 101 to the distal end 102, and the first protrusion 231 of the first locking portion 23 may protrude away from the central axis CA. In this case, by expanding the first locking portion 23 as a whole outwards, an interlock can be formed with the first holding portion 12 on the outside (away from the central axis CA), and by actuating the first locking portion 23 towards the inside (close to the central axis CA), the first locking portion 23 can be disengaged from the first holding portion 12 and released.

[0112] In some examples, the first protrusion 231 may have a surface facing the proximal end 101. In some examples, the surface of the first protrusion 231 facing the proximal end 101 may be substantially orthogonal to the central axis CA. The first locking portion 23 can be held by lapping / abutting against the surface of the first holding portion 12 facing the distal end 102. Thereby, it can help to inhibit the movement of the moving body 20 towards the proximal end 101. When the first locking portion 23 is actuated to move the surface of the first protrusion 231 facing the proximal end 101 away from its original position, that is, no longer lapping against the surface of the first holding portion 12 facing the distal end 102, the first locking portion 23 is released. That is to say, the first locking portion 23 can be a structure such as a buckle, hook, latch, or pin formed on the moving body 20. For example, the first locking portion 23 can be formed into a structure that can be at least decomposed into two parts, such as a finger shape, a straight shape, an L shape, a J shape, or a Z shape. At least a part thereof (for example, the first arm 230 connected to the side wall 22 of the moving body 20) can pivot, and the other part (for example, the convex structure protruding outward from the first arm 230 and abutting against the first holding portion 12) can leave the initial position along with the pivot, thereby releasing the hooking, hanging, latching, pushing, supporting, etc. of the held member.

[0113] In some examples, the number of the first holding portions 12 can be one or more. For example, the number of the first holding portions 12 can be 1, 2, 3, or 4. Correspondingly, the number of the first locking portions 23 can be the same as the number of the first holding portions 12. In Figure 12 the illustrated embodiment, the number of the first locking portions 23 is 2, and the two first locking portions 23 can be symmetrically distributed on the opposite sides of the moving body 20. Thereby, it can help to stably hold the moving body 20 and improve the reliability of the applying device 100.

[0114] In some examples, as described above, the first housing 10 and the second housing 30 can move relative to each other to release the moving body 20. In some examples, the second housing 30 can include a first trigger portion 33. The first trigger portion 33 can be configured to separate the first holding portion 12 from the first locking portion 23 to release the moving body x0. Thereby, through the first trigger portion 33, it is convenient to release the moving body 20 by the relative movement of the two housings.

[0115] In some examples, the second housing 30 and the first housing 10 can move relative to each other in a way of approaching each other to release the holding of the first holding portion 12 on the moving body 20. In some examples, the first housing 10 and the second housing 30 can move relative to each other along the direction of the central axis CA to release the holding of the first holding portion 12 on the moving body 20. In this case, by moving the two housings relative to each other along the direction of the central axis CA, the first locking portion 23 can be separated from the first holding portion 12 through the first trigger portion 33, which is convenient for the operator to use. InFigure 12 In the illustrated example, the relative movement of the first housing 10 and the second housing 30 toward each other may include the first housing 10 moving in the direction F1 (i.e., moving toward the proximal end 101), the second housing 30 moving in the direction F2 (i.e., moving toward the distal end 102), or the first housing 10 moving in the direction F1 while the second housing 30 moves in the direction F2.

[0116] In some examples, the first trigger portion 33 may be formed on the side wall of the second housing 30. In some examples, the first trigger portion 33 may include a trigger arm 330 extending generally along the direction of the central axis CA (see Figure 13 ). When the first housing 10 and the second housing 30 move relative to each other, the trigger arm 330 may act on the first locking portion 23 to separate the first locking portion 23 from the first holding portion 12.

[0117] In some examples, the first locking portion 23 may include a protrusion 232 protruding away from the central axis CA in a direction generally orthogonal to the central axis CA (for ease of reading, the protrusion 232 will be referred to as the second protrusion 232 hereinafter) (see Figure 11 ). The second protrusion 232 may be provided on the first arm 230. In some examples, the first trigger portion 33 may exert an action on the second protrusion 232 to deflect the first arm 230.

[0118] In some examples, the surface of the second protrusion 232 facing the proximal end 101 and / or the surface of the trigger arm 330 facing the distal end 102 may be an inclined surface or a curved surface. In this case, it is possible to facilitate the movement of the second protrusion 232 when it abuts against the trigger arm 330 under the action of the trigger arm 330. When the first housing 10 and the second housing 30 move relative to each other in a manner that they approach each other, the first trigger portion 33 first moves to abut against the second protrusion 232, causing the surface of the trigger arm 330 facing the distal end 102 to contact the surface of the second protrusion 232 facing the proximal end 101. And during the continuous movement, the second protrusion 232 is squeezed, causing the first arm 230 to gradually deflect toward the central axis CA. When the first arm 230 deflects away from the first holding portion 12, the moving body 20 is in a released state. Thus, it is possible to facilitate unlocking the moving body 20 by the relative movement of the first housing 10 and the second housing 30, thereby facilitating the operator's use.

[0119] In some examples, the surface of the second protrusion 232 facing the proximal end 101 and / or the surface of the trigger arm 330 facing the distal end 102 may be an inclined surface or a curved surface. In this case, it is possible to facilitate the movement of the second protrusion 232 when it abuts against the trigger arm 330 under the action of the trigger arm 330.

[0120] In some examples, when the moving body 20 is held at the first holding portion 12, compared with both the first protrusion 231 and the second protrusion 232, the second protrusion 232 is closer to the first trigger portion 33. That is to say, when the moving body 20 is held at the first holding portion 12, in the direction from the proximal end 101 to the distal end 102, compared with both the first protrusion 231 and the second protrusion 232, the second protrusion 232 is closer to the proximal end 101. In this case, it is convenient to unlock the moving body 20 by the relative movement of the first housing 10 and the second housing 30 in a mutually approaching manner.

[0121] In some examples, the first protrusion 231 and the second protrusion 232 may be arranged in a staggered manner in the vertical direction and / or the horizontal direction. Among them, the first protrusion 231 and the second protrusion 232 being arranged in a staggered manner in the vertical direction may mean that the axes of the first protrusion 231 and the second protrusion 232 in the vertical direction do not overlap, or when projected along the vertical direction, the first protrusion 231 and the second protrusion 232 do not overlap each other; the meaning of being arranged in a staggered manner in the horizontal direction is the same as that in the vertical direction. In this case, since the first protrusion 231, the second protrusion 232, the first holding portion 12 of the first housing 10, and the trigger arm 330 of the second housing 30 are related to each other, when designing, it is necessary to consider the positional relationship between each component, and also consider the utilization rate of the internal space of the first housing 10. In this embodiment, the first protrusion 231 and the second protrusion 232 are configured to be arranged in a staggered manner in the vertical direction and / or the horizontal direction. Compared with the scheme of arranging the two protrusions on the same axis, it can save space, improve the integration degree of the internal structure of the applying device 100, and contribute to the miniaturization of the applying device 100.

[0122] In some examples, the first protrusion 231 and the second protrusion 232 may be arranged in a staggered manner both in the vertical direction and the horizontal direction. When the moving body 20 is held at the first holding portion 12, the first holding portion 12 may be horizontally adjacent to the second protrusion 232 and contact the first protrusion 231. At this time, the first holding portion 12 may overlap with the first protrusion 231 in the vertical direction. In this case, when the first protrusion 231 is actuated to disengage from the first holding portion 12, the second protrusion 232 and the trigger arm 330 are not on the path of the first protrusion 231 moving toward the proximal end 101, which is beneficial for the moving body 20 to be smoothly actuated to the host.

[0123] In some examples, in one first locking portion 23, the number of the second protrusions 232 may be one or more. For example, the number of the second protrusions 232 may be 1, ...... Figure 12In the illustrated embodiment, the number of the second protrusions 232 is four (one of the second protrusions 232 is not shown due to the viewing angle), and the four second protrusions 232 are arranged in pairs on the first locking portion 23. Correspondingly, the number of the first triggering portions 33 may be the same as that of the second protrusions 232. In Figure 12 the illustrated embodiment, the number of the first triggering portions 33 is four, and the positions of the four first triggering portions 33 correspond to those of the four second protrusions 232. In this case, it is helpful to separate the first locking portion 23 and the first holding portion 12 by applying an action from the first triggering portion 33 to the second protrusion 232 when the two housings move relative to each other.

[0124] Figure 11 FIG. is a schematic cross-sectional view before the first locking portion 23 involved in the example of the present disclosure is triggered by the first triggering portion 33. Figure 14 FIG. is a schematic cross-sectional view after the first locking portion 23 involved in the example of the present disclosure is triggered by the first triggering portion 33. It should be noted that Figure 15 and Figure 14 are Figure 15 an enlarged view of area A in Figure 13 and Figure 14 mainly show the triggering of the first locking portion 23 by the first triggering portion 33. For clearer illustration, some lines that may cause occlusion are omitted, and the gaps between the components are enlarged; in addition, in Figure 15 only the first holding portion 12, the first locking portion 23 and the first triggering portion 33 are labeled for clearer illustration. For the specific structural details of these components, reference can be made to Figure 15 .

[0125] Hereinafter, referring to Figure 14 and Figure 14 , the triggering of the first locking portion 23 by the first triggering portion 33 will be described in detail. As described above, before the first triggering portion 33 actuates the first locking portion 23, the first locking portion 23 contacts the first holding portion 12, and the first holding portion 12 can restrict the movement of the first locking portion 23 toward the proximal end 101 to hold the moving body 20 (see Figure 15 ). When the first triggering portion 33 actuates the first locking portion 23 (for example, when the two housings move relative to each other in a way of approaching each other), under the action of the first triggering portion 33, the first arm 230 and the first protrusion 231 gradually fold inward (i.e., move in the direction close to the central axis CA). When the first protrusion 231 separates from the first holding portion 12, the moving body 20 can be released (see Figure 14 ).

[0126] In some examples, after the moving body 20 is released, it can move towards the proximal end 101. In some examples, when the moving body 20 applies the monitoring device 800 to the host, the end of the moving body 20 close to the proximal end 101 can be flush with the proximal end 101 of the applying device 100. Thereby, it is convenient to apply the monitoring device 800 located in the accommodating portion 21 to the host.

[0127] In some examples, the first holding portion 12 has a surface facing the proximal end 101. In some examples, the first triggering portion 33 has a first surface 331 and a second surface 332 facing the distal end 102 (see Figure 15 ). Among them, the first surface 331 can face the first locking portion 23, and the second surface 332 can face the first holding portion 12. When the first housing 10 and the second housing 30 move relative to each other in a mutually approaching manner, during the movement, the first surface 331 can first contact the first locking portion 23 and exert an action on the first locking portion 23. During the continued movement, the second surface 332 can contact the surface of the first holding portion 12 facing the proximal end 101. Thereby, it is convenient to exert an action on the first locking portion 23 towards the center axis CA to separate the first locking portion 23 from the first holding portion 12.

[0128] In some examples, when the first housing 10 and the second housing 30 move relative to each other along the direction of the center axis CA, the first triggering portion 33 can act on the first locking portion 23 to separate the first locking portion 23 from the first holding portion 12. In this case, by moving the two housings relative to each other along the direction of the center axis CA, the first locking portion 23 can be separated from the first holding portion 12 through the first triggering portion 33, which is convenient for the operator to use.

[0129] In some examples, the proximal surface 31 of the second housing 30 can be placed on the skin of the host, and an action towards the host is applied to the first housing 10 (for example, the operator presses the first housing 10 towards the host), so that the first housing 10 and the second housing 30 perform a relative movement of approaching each other, thereby releasing the moving body 20. After the moving body 20 is released, it moves towards the proximal end 101 together with the puncturing member 40 to apply the monitoring device 800 to the body surface of the host, and at least part of the monitoring device 800 is introduced subcutaneously into the host through the puncturing member 40. Thereby, it is convenient for the host to operate the applying device 100 with one hand.

[0130] In some examples, the second housing 30 can include one or more protruding structures 391 (see Figure 14)。In some examples, the protruding structure 391 may protrude from the inner wall of the second housing 30 in a direction substantially orthogonal to the central axis CA and away from the central axis CA. In some examples, the protruding structure 391 may be in clearance fit with the inner wall of the first housing 10. In this case, the protruding structure 391 can help to suppress the undesired wobbling and / or rotation of the second housing 30 inside the first housing 10, thereby improving the reliability of the application device 100. In some examples, a plurality of protruding structures 391 may be dispersedly provided on the outer periphery of the second housing 30.

[0131] In some examples, the first housing 10 may include a first restricting portion 13 (see Figure 11 ). The first restricting portion 13 may impose a restriction on the second housing 30 to prevent the second housing 30 from detaching from the first housing 10. Thereby, it can help to improve the reliability of the application device 100. That is, in some examples, the first housing 10 may include a first restricting portion 13 configured to prevent the second housing 30 from detaching from the first housing 10.

[0132] In some examples, the first restricting portion 13 may be a convex structure formed on the inner wall of the first housing 10 (see Figure 10 ).

[0133] In some examples, the second housing 30 may include a first restricted portion 34 (see Figure 10 ). The first restricted portion 34 may be coupled to the first restricting portion 13. In some examples, the first restricted portion 34 may be provided on the side wall of the second housing 30. In some examples, the interlocking between the first restricting portion 13 and the first restricted portion 34 may be achieved by at least one of a buckle, a hook, a latch, or a pin structure.

[0134] In some examples, when the moving body 20 is held by the first holding portion 12, the first restricted portion 34 may be coupled to the first restricting portion 13. Thereby, a restriction can be imposed on the second housing 30 in the standby state where the moving body 20 is held by the first holding portion 12 to prevent the second housing 30 from detaching from the first housing 10.

[0135] In some examples, the first restricting portion 13 may have a surface facing the distal end 102. In some examples, the first restricted portion 34 may have a surface facing the proximal end 101. When the moving body 20 is held by the first holding portion 12, the surface of the first restricting portion 13 facing the distal end 102 may be engaged with the surface of the first restricted portion 34 facing the proximal end 101. In some examples, when the moving body 20 is held by the first holding portion 12, the first restricted portion 34 is closer to the distal end 102 than the first restricting portion 13.

[0136] In some examples, the first restricting portion 34 may include an extension portion 340 extending substantially along the direction of the central axis CA, and a clamping portion 341 linked to the extension portion 340 (see Figure 11 ). When the clamping portion 341 is engaged with the first restricting portion 13, the second housing 30 may be restricted by the first housing 10.

[0137] In some examples, the first housing 10 may include a second restricting portion 14 (see Figure 11 ). The second restricting portion 14 may impose a restriction on the second housing 30. Specifically, the second restricting portion 14 may be configured to inhibit the movement of the second housing 30 toward the proximal end 101. After the relative movement between the first housing 10 and the second housing 30 releases the movement body 20, the second housing 30 may be restricted by the second restricting portion 14. In this case, the movement of the second housing 30 toward the proximal end 101 can be restricted by the second restricting portion 14, thereby inhibiting the operator from reusing the application device 100, and reducing the risk of the used puncturing member 40 that has not been disinfected again coming into contact with the host. In some examples, the second restricting portion 14 may be a convex structure formed on the inner wall of the first housing 10.

[0138] In some examples, the second housing 30 may include a second restricted portion 35 (see Figure 10 ). The second restricted portion 35 may be configured to interlock with the second restricting portion 14. Thus, the second housing 30 can be held in the first holding portion 12 through the cooperation between the second restricted portion 35 and the second restricting portion 14. Specifically, after the relative movement between the first housing 10 and the second housing 30 releases the holding of the movement body 20 by the first holding portion 12, the second restricted portion 35 may engage with the second restricting portion 14.

[0139] In some examples, when the movement body 20 is held in the first holding portion 12, the second restricted portion 35 is closer to the proximal end 101 than the second restricting portion 14; when the movement body 20 is in the released state, the second restricted portion 35 is closer to the distal end 102 than the second restricting portion 14. In some examples, the interlock between the second restricting portion 14 and the second restricted portion 35 may be achieved by at least one of a buckle, a hook, a latch, or a pin structure.

[0140] In some examples, the second restricting portion 14 may have a surface facing the distal end 102. In some examples, the second restricted portion 35 may have a surface facing the proximal end 101. When the second housing 30 is held, the surface of the second restricting portion 14 facing the distal end 102 and the surface of the second restricted portion 35 facing the proximal end 101 may be engaged with each other.

[0141] In some examples, the structure of the second limiting part 35 may be the same as that of the first limiting part 34. That is to say, the second limiting part 35 may also include an extension part 340 and a clamping part 341. In some examples, the first limiting part 34 and the second limiting part 35 may be the same structure. That is to say, in addition to cooperating with the first limiting part 13, the first limiting part 34 may also cooperate with the second limiting part 14 to hold the second housing 30. In other words, in some examples, the first limiting part 34 may be configured to cooperate with the second limiting part 14 to hold the second housing 30. Thus, it can help to simplify the structure of the applying device 100.

[0142] In some examples, the first limiting part 34 may form a structure similar to an H-shaped structure or an arch-shaped structure (see Figure 11 ). In this case, by overlapping the crossbar structure in the first limiting part 34 on the first limiting part 13 or the second limiting part 14, the second housing 30 can be limited by the first limiting part 13 or the second limiting part 14. In some examples, the extension part 340 and the clamping part 341 may cooperate to form a structure similar to an H-shaped structure or an arch-shaped structure. Among them, the extension part 340 may constitute the vertical structure in the H-shaped structure or the arch-shaped structure, and the clamping part 341 may constitute the crossbar structure in the H-shaped structure. In this case, on the one hand, the cooperation of the vertical structure helps to suppress the undesired rotation of the second housing in the first housing; on the other hand, compared with the L-shaped structure, the structure formed by the extension part 340 and the clamping part 341 is a single-layer structure in the same thickness direction, while the L-shaped structure is a double-layer structure. Therefore, setting the single-layer structure helps to reduce the required space in the same width direction of the applying device 100, so as to facilitate the cooperation with other components to form a compact structure and improve the utilization rate of the internal space of the first housing. In other examples, the extension part 340 and the clamping part 341 may also cooperate to form structures such as an L-shaped, J-shaped or Z-shaped structure.

[0143] In other examples, the extension part 340 may be an arm extending along the direction of the central axis CA (for the convenience of reading, this arm will be referred to as the second arm later) (see Figure 11 ). In some examples, the clamping part 341 may be provided on the extension part 340 (see Figure 11 ). In this case, it can help the extension part 340 and the clamping part 341 to cooperate to form a structure that can be coupled with the first limiting part 13 and the second limiting part 14. In some examples, the clamping part 341 and the extension part 340 may be integrally formed.

[0144] In some examples, the second arm can be elastic. In some examples, the second arm can be elastic in a direction substantially orthogonal to the central axis CA. In some examples, the second arm can tend to expand away from the central axis CA in the direction from the proximal end 101 to the distal end 102. That is, in the natural state (i.e., the state without external force), compared with the end of the second arm near the proximal end 101 and the end of the second arm near the distal end 102, the distance between the end of the second arm near the proximal end 101 and the central axis CA is closer. In some other examples, the second arm can also be substantially parallel to the central axis CA.

[0145] In some examples, when an action is applied to the second arm in a direction substantially orthogonal to the central axis CA, the second arm can pivot. For example, when an action is applied to the second arm in a direction substantially orthogonal to the central axis CA and towards the central axis CA, the second arm can deflect so that the end of the second arm near the distal end 102 moves towards the central axis CA. In this case, when the first housing 10 and the second housing 30 move relative to each other in a closer manner, the second arm can be deflected so that the engaging portion 341 of the second restricting portion 35 straddles the second restricting portion 14 and overlaps with the second restricting portion 14.

[0146] In some examples, the second arm can be formed on the side wall of the second housing 30. In some examples, the second arm can also be a part of the side wall of the second housing 30. When the engaging portion 341 of the second restricting portion 35 overlaps with the second restricting portion 14, the second housing 30 can be held.

[0147] In some examples, the second arm can expand in a direction away from the central axis CA in the direction from the proximal end 101 to the distal end 102, and the engaging portion 341 can protrude in a direction away from the central axis CA. In this case, by expanding the second restricting portion 35 as a whole outwards, an interlock can be formed with the second restricting portion 14 on the outside (away from the central axis CA).

[0148] In some examples, the second limiting portion 14 may have a surface facing the proximal end 101. In some examples, the latching portion 341 may have a surface facing the distal end 102. When the first housing 10 and the second housing 30 move relatively closer to each other, the surface of the latching portion 341 facing the distal end 102 first contacts the surface of the second limiting portion 14 facing the proximal end 101. During the continuous movement, the latching portion 341 is squeezed by the second limiting portion 14 and is deflected as a whole in the direction close to the central axis CA. When it moves to a position where the surface of the latching portion 341 facing the proximal end 101 is closer to the distal end 102 than the surface of the second limiting portion 14 facing the distal end 102, the latching portion 341 expands outward after being separated from the extrusion of the second limiting portion 14, so that the surface of the second limiting portion 14 facing the distal end 102 and the surface of the latching portion 341 facing the proximal end 101 are engaged with each other to hold the second housing 30.

[0149] In some examples, the surface of the second limiting portion 14 facing the proximal end 101 and / or the surface of the latching portion 341 facing the distal end 102 may be an inclined surface or a curved surface. In this case, when the two housings move relatively, it is convenient for the latching portion 341 to smoothly cross the surface of the second limiting portion 14 facing the proximal end 101 and overlap with the second limiting portion 14 under the extrusion of the second limiting portion 14.

[0150] In some examples, after the moving body 20 is released, the first restricted portion 34 may be separated from the first limiting portion 13. In some examples, after the moving body 20 is released, the second housing 30 may be held by the second restricted portion 35 on the second limiting portion 14.

[0151] In some examples, the structure of the first limiting portion 13 may be the same as that of the second limiting portion 14. In some examples, the first limiting portion 13 and the second limiting portion 14 may be arranged adjacent to each other in the direction along the central axis CA. In some examples, the first limiting portion 13 is closer to the proximal end 101 than the second limiting portion 14. In this case, before the moving body 20 is released, the second housing 30 can be restricted by the first housing 10 through the cooperation of the first restricted portion 34 and the first limiting portion 13. When the first housing 10 and the second housing 30 move relatively closer to each other to release the moving body 20, the second housing 30 can be restricted by the first housing 10 through the cooperation of the first restricted portion 34 and the second limiting portion 14.

[0152] In some examples, the number of first restricting portions 13 may be one or more. For example, the number of first restricting portions 13 may be one, two, three, or four. The number of first restricting portions 34 may be the same as the number of first restricting portions 13. In some examples, the number of second restricting portions 14 may be one or more. For example, the number of second restricting portions 14 may be one, two, three, or four.

[0153] Figure 11 1 is a schematic cross-sectional view showing that the first restricting portion 34 according to the example of the present disclosure is not engaged with the second restricting portion 14 . Figure 16 1 is a cross-sectional view showing the engagement of the first limiting portion 34 and the second limiting portion 14 according to the example of the present disclosure. Figure 17 and Figure 16 The figure mainly illustrates the cooperation among the first limiting portion 34, the first limiting portion 13 and the second limiting portion 14, and omits some lines that may cause obstruction or misunderstanding.

[0154] See below Figure 17 and Figure 16 , the cooperation between the first limiting portion 34, the first limiting portion 13 and the second limiting portion 14 is described in detail. As mentioned above, before the first triggering portion 33 actuates the first locking portion 23 (i.e., when the moving body 20 is kept in the standby state of the first holding portion 12), the first limiting portion 34 can engage with the first limiting portion 13, and the movement of the second housing 30 toward the proximal end 101 can be limited by the first limiting portion 13 (see Figure 17 ); When the two shells move relative to each other in the direction of the central axis CA, the first limiting portion 34 is squeezed inward by the second limiting portion 14, and the second arm and the clamping portion 341 gradually retract inward (i.e., move in the direction close to the central axis CA). When the surface of the clamping portion 341 facing the proximal end 101 is higher than the surface of the second limiting portion 14 facing the distal end 102, the clamping portion 341 is released from the squeezing of the second limiting portion 14 and expands outward, so that the surface of the second limiting portion 14 facing the distal end 102 and the surface of the clamping portion 341 facing the proximal end 101 engage with each other to hold the second shell 30 (see Figure 16 ).

[0155] In some examples, the second limiting portion 14 may not be provided. In this case, after the action that makes the first housing 10 and the second housing 30 move relative to each other is stopped, the second housing 30 and the first housing 10 can automatically return to the standby position for the next use. In an example of the reusable application device 100, the needle-like portion 41 and the support base 43 in the puncture member 40 can be configured to be detachably engaged. After one application action is completed, the needle-like portion 41 can be detached from the support base 43, a new sterilized needle-like portion 41 can be replaced, and a new monitoring device 800 can be assembled to the application device 100 for the next use.

[0156] In some examples, a male-female mechanical mating structure may be provided on the side wall of the second housing 30 and the side wall 22 of the moving body 20. In some examples, the second housing 30 may include a third engaging feature 38, and the moving body 20 may include a fourth engaging feature 28 (see Figure 17 and Figure 11 ). A male-female mechanical mating structure can be formed by the cooperation of the third engaging feature 38 and the fourth engaging feature 28. In some examples, the male-female mechanical mating structure may be a concave-convex mating structure. In some examples, the third engaging feature 38 may be one or more rib-like protrusions provided on the side wall of the second housing 30, and the fourth engaging feature 28 may be one or more rib-like grooves provided on the side wall 22 of the moving body 20 (see Figure 12 and Figure 11 ). In some examples, when the moving body 20 is assembled to the second housing 30, one or more rib-like protrusions of the second housing 30 can be respectively embedded into one or more rib-like grooves of the moving body 20. In this case, on the one hand, through the matching of the rib-like protrusions and the rib-like grooves, it is possible to facilitate the assembly of the second housing 30 and the moving body 20; on the other hand, the moving direction of the moving body 20 can also be guided by the rib-like protrusions and the rib-like grooves; in addition, the cooperation of the rib-like protrusions and the rib-like grooves can also help to suppress the unwanted rotation of the moving body 20.

[0157] In some examples, the plurality of rib-like protrusions provided on the side wall of the second housing 30 can be evenly or symmetrically distributed on the side wall of the second housing 30.

[0158] In some examples, the second housing 30 may include a third limiting portion 36 (see Figure 12)。The third restricting portion 36 can impose a restriction on the moving body 20. In some examples, the third restricting portion 36 can be at least partially located on the travel path of the moving body 20 moving toward the proximal end 101. In this case, when the moving body 20 moves toward the proximal end 101 to the third restricting portion 36, the moving body 20 can be restricted by the third restricting portion 36 to stop moving. On the one hand, the monitoring device 800 can be applied to a predetermined position, and on the other hand, the moving body 20 can be inhibited from detaching from the second housing 30. Thereby, the reliability of the applying device 100 can be improved.

[0159] In some examples, the moving body 20 can include a third restricted portion 24 (see Figure 11 )。The third restricted portion 24 can be coupled with the third restricting portion 36 to restrict the moving body 20 to the second housing 30. In some examples, the interlock between the third restricting portion 36 and the third restricted portion 24 can be achieved by at least one of structures such as a buckle, a hook, a latch, or a pin. In some examples, the third restricting portion 36 can be provided on the side wall of the second housing 30. In some examples, the third restricted portion 24 can be provided on the side wall 22 of the moving body 20.

[0160] In some examples, when the moving body 20 is held by the first holding portion 12, the third restricted portion 24 is closer to the distal end 102 than the third restricting portion 36. In some examples, the third restricting portion 36 can have a surface facing the distal end 102. In some examples, the third restricted portion 24 can have a surface facing the proximal end 101. When the moving body 20 moves toward the proximal end 101 until the third restricted portion 24 contacts the third restricting portion 36, the surface of the third restricting portion 36 facing the distal end 102 can engage with the surface of the third restricted portion 24 facing the proximal end 101.

[0161] In some examples, the third restricted portion 24 can include an arm 240 (hereinafter referred to as the third arm 240 for convenience of reading) extending substantially along the direction of the central axis CA, and a protrusion 241 (hereinafter referred to as the third protrusion 241 for convenience of reading) that is linked with the third arm 240 and protrudes away from the central axis CA along a direction substantially orthogonal to the central axis CA). In this case, when the third protrusion 241 of the third restricted portion 24 overlaps the third restricting portion 36, the moving body 20 can be restricted.

[0162] In some examples, the third arm 240 can be elastic. In some examples, the third arm 240 can be elastic in a direction substantially orthogonal to the central axis CA. In some examples, when an action is applied to the third arm 240 in a direction substantially orthogonal to the central axis CA, the third arm 240 can pivot. In this case, it is convenient to assemble the moving body 20 to the second housing 30. In some examples, the third arm 240 can tend to expand away from the central axis CA in the direction from the proximal end 101 to the distal end 102. In this case, after the moving body 20 and the second housing 30 are assembled in place, it can help the third protrusion 241 to be located above the third limiting portion 36, so that the third protrusion 241 can overlap with the third limiting portion 36 when the moving body 20 moves toward the proximal end 101 subsequently.

[0163] In some examples, the axis of the second housing 30 and the axis of the moving body 20 can be substantially parallel to the central axis CA. In some examples, the second housing 30 and the moving body 20 can be coaxially arranged. For example, in Figure 12 the axis of the second housing 30 and the axis of the moving body 20 can overlap with the central axis CA. In some examples, the second housing 30 and the moving body 20 can be arranged in an overlapping manner. Specifically, a hollowed-out portion 39 (see Figure 8 ) can be provided on the second housing 30, and some components of the moving body 20 (such as the first locking portion 23) can penetrate into the hollowed-out portion 39. In this case, the utilization rate of the internal space of the first housing 10 can be improved, which helps to miniaturize the application device 100. In some examples, the moving body 20 can be movably embedded in the second housing 30.

[0164] In some examples, the number of the third limiting portions 36 can be one or more. For example, the number of the third limiting portions 36 can be 1, 2, 3, or 4. The number of the third restricted portions 24 and the third limiting portions 36 can be the same.

[0165] In some examples, the moving body 20 can include a side wall and a first bottom 25 facing the proximal end 101 (see Figure 11 ). In some examples, the first driving portion 51 can be located between the first housing 10 and the moving body 20. Thus, it is convenient for the first driving portion 51 to apply an action to the moving body 20. For example, in some examples, the first driving portion 51 can be located between the first housing 10 and the first bottom 25 of the moving body 20. Again, for example, in some examples, the first driving portion 51 can be located between the first housing 10 and the top of the moving body 20.

[0166] In some examples, a first positioning portion 251 for positioning the first driving portion 51 may be provided on the first bottom 25. In this case, the position where the first driving portion 51 acts on the moving body 20 can be more stably defined by the first positioning portion 251.

[0167] In some examples, the first positioning portion 251 of the first bottom 25 may be a stepped structure protruding from the first bottom 25 along the central axis CA toward the distal end 102. The first driving portion 51 may be located in a groove-shaped space formed by the cooperation of the stepped structure and the side wall of the second housing 30. In some examples, the first driving portion 51 may be sleeved on the outer periphery of the side wall 22 of the moving body 20 and abutted against the first positioning portion 251.

[0168] In some examples, the first positioning portion 251 may be cylindrical. In some examples, the first positioning portion 251 may be a solid cylindrical shape, and the first driving portion 51 may be sleeved on the outer periphery of the first positioning portion 251. In other examples, the first positioning portion 251 may be a hollow cylindrical shape, and the first driving portion 51 may be either sleeved on the outer periphery of the first positioning portion 251 or embedded in the inner periphery of the first positioning portion 251.

[0169] In some examples, the first driving portion 51 may have an energy storage state and an energy release state. When the first driving portion 51 switches from the energy storage state to the energy release state, the first driving portion 51 can release energy and act on the moving body 20 in a direction toward the proximal end 101. When the moving body 20 is held, the first driving portion 51 may exist between the moving body 20 and the first housing 10 in the energy storage state. When the moving body 20 is released, the first driving portion 51 can switch from the energy storage state to the energy release state and act on the moving body 20 in a direction toward the proximal end 101.

[0170] In some examples, the first driving portion 51 may have a compressed state and an extended state. When the first driving portion 51 switches from the compressed state to the extended state, the first driving portion 51 can release energy. In some examples, the first driving portion 51 may be an elastic element. In some examples, both ends of the first driving portion 51 may respectively abut against the first housing 10 and the first bottom 25. When the moving body 20 is held by the first holding portion 12, the first driving portion 51 may be in the compressed state. In this case, when the moving body 20 is released, the first driving portion 51 in the compressed state can automatically apply a force to the moving body 20 to realize the automatic pushing of the moving body 20, which is convenient for the operator to use. In some examples, the first driving portion 51 may be a spring.

[0171] In some examples, one end of the first driving part 51 can be sleeved on the first positioning part 251 of the first bottom 25. In some examples, the first housing 10 can have a second positioning part 15 (see Figure 12 ). In some examples, the second positioning part 15 can be cylindrical. In this case, the other end of the first driving part 51 can be sleeved on the second positioning part 15. In some examples, the second positioning part 15 can be a hollow cylinder. In this case, the other end of the first driving part 51 can be sleeved or embedded in the second positioning part 15. In some examples, the second positioning part 15 can be composed of at least two arc-shaped columns. In this case, the other end of the first driving part 51 can be embedded between the arc-shaped columns.

[0172] In addition, the applying device 100 of the present embodiment is not limited to this. In some examples, the applying device 100 may not include the first driving part 51. In this case, when the moving body 20 is released, the moving body 20 can also be moved toward the proximal end 101 by manually applying an action to the moving body 20.

[0173] Figure 10 is an exploded schematic view of the first perspective of the moving body 20 and the puncturing member 40 involved in the example of the present disclosure; Figure 18 is an exploded schematic view of the second perspective of the moving body 20 and the puncturing member 40 involved in the example of the present disclosure; Figure 19 is a schematic cross-sectional view of the puncturing member 40 being held involved in the example of the present disclosure.

[0174] In some examples, the moving body 20 and the puncturing member 40 can be integrally and fixedly connected. In other examples, the moving body 20 and the puncturing member 40 can be detachably assembled and combined. In some examples, the puncturing member 40 can be releasably held by the moving body 20.

[0175] In some examples, the moving body 20 can include a hollow part 26 (see Figure 20 ). Specifically, the side wall 22 of the moving body 20 and the first bottom 25 of the moving body 20 facing the proximal end 101 can cooperate to form the hollow part 26. In some examples, the puncturing member 40 can be releasably arranged in the hollow part 26 of the moving body 20. In some examples, when the puncturing member 40 is released, it can move along the hollow part 26 of the moving body 20. In this case, by forming the hollow part 26 through the first bottom 25 and the side wall, arranging the storage part 21 on the first bottom 25, and arranging the puncturing member 40 in the hollow part 26, it is convenient for the puncturing member 40 to move relative to the storage part 21 when it is released. Thus, when the monitoring device 800 is applied to the host, the puncturing member 40 is released and moves relative to the storage part 21, so that the puncturing member 40 can leave the host.

[0176] In some examples, the moving body 20 may include a second through hole 260 that connects the accommodating portion 21 and the hollow portion 26 (see Figure 18 ). In some examples, the puncturing member 40 may contact the monitoring device 800 through the second through hole 260. Thereby, it is possible to facilitate the at least partial introduction of the monitoring device 800 into the subcutaneous tissue of the host through the puncturing member 40 during the application process.

[0177] In other examples, the puncturing member 40 may also be fixedly provided on the moving body 20. In this case, when the monitoring device 800 is applied to the host, the moving body 20 can be integrally separated from the host by means of human power, and thereby, the puncturing member 40 can also be separated from the host.

[0178] In some examples, the second driving portion 52 may be located between the moving body 20 and the puncturing member 40. In some examples, the second driving portion 52 may be located between the first bottom portion 25 and the puncturing member 40. The second driving portion 52 may be configured to act on the puncturing member 40 toward the distal end 102. When the puncturing member 40 is released, the second driving portion 52 may act on the puncturing member 40 toward the distal end 102 to cause the puncturing member 40 to leave the host. Thereby, it is possible to help more accurately control the timing of the puncturing member 40 leaving the host.

[0179] In some examples, the second driving portion 52 may have an energy storage state and an energy release state. When the second driving portion 52 switches from the energy storage state to the energy release state, the second driving portion 52 may release energy and act on the puncturing member 40 in a direction toward the distal end 102. When the puncturing member 40 is held, the second driving portion 52 may exist between the moving body 20 and the puncturing member 40 in the energy storage state. When the puncturing member 40 is released, the second driving portion 52 may switch from the energy storage state to the energy release state and act on the puncturing member 40 in a direction toward the distal end 102.

[0180] In some examples, the second driving part 52 can have a compressed state and an extended state. When the second driving part 52 switches from the compressed state to the extended state, the second driving part 52 can release energy. In some examples, the second driving part 52 can be an elastic element. In some examples, both ends of the second driving part 52 can respectively abut against the first bottom 25 and the puncturing member 40. That is to say, both ends of the second driving part 52 can respectively abut against the moving body 20 and the puncturing member 40. When the puncturing member 40 is held, the second driving part 52 can be in a compressed state. In this case, when the puncturing member 40 is released, the second driving part 52 in the compressed state can automatically apply a force to the puncturing member 40 so as to realize the automatic retraction of the puncturing member 40, thereby facilitating the use by the operator. In some examples, the second driving part 52 can be a spring.

[0181] In some examples, as described above, the puncturing member 40 can include a needle-like part 41 and a bearing part 42 connected to the needle-like part 41 (see ' ). In some examples, a groove extending along the length direction of the needle-like part 41 can be provided on the needle-like part 41. The sensor 8 can be at least partially disposed in the groove of the needle-like part 41. In this case, the sensor 8 can be received in the groove so as to facilitate placing the sensor 8 under the skin of the host along with the needle-like part 41.

[0182] In some examples, the puncturing member 40 can include a support seat 43 for supporting the needle-like part 41 (see Figure 19 ). The support seat 43 can support the needle-like part 41 via the bearing part 42.

[0183] In some examples, the support seat 43 can be disposed in the hollow part 26 of the moving body 20, and the bearing part 42 and / or the needle-like part 41 can pass through the second through hole 260. In this case, by setting the bearing part 42 and / or the needle-like part 41 to pass through the second through hole 260, the bearing part 42 and / or the needle-like part 41 can be engaged with the monitoring device 800 accommodated in the storage part 21, which can facilitate placing at least part of the monitoring device 800 under the skin of the host through the puncturing member 40.

[0184] In some examples, the moving body 20 can include a third positioning part 252 (see Figure 18 ). The third positioning part 252 can be used to position the second driving part 52. In this case, the position where the second driving part 52 acts on the puncturing member 40 can be more stably defined by the third positioning part 252. In some examples, the third positioning part 252 can be disposed on the first bottom 25.

[0185] In some examples, one end of the second driving part 52 can be sleeved on the third positioning part 252 of the first bottom part 25. In some examples, the third positioning part 252 can be cylindrical. In this case, one end of the first driving part 51 can be sleeved on the third positioning part 252. In some examples, the puncturing member 40 can have a fourth positioning part 44 (see Figure 18 ). In some examples, the fourth positioning part 44 can be a hollow cylindrical protrusion formed on the support seat 43. In this case, the end of the second driving part 52 in contact with the puncturing member 40 can be sleeved or embedded in the fourth positioning part 44. In some examples, the third positioning part 252 and / or the fourth positioning part 44 can be composed of at least two arc-shaped columns. In this case, the end of the first driving part 51 can be embedded between the arc-shaped columns.

[0186] In some examples, the needle part 41 and the support seat 43 can be integrally formed. In other examples, the needle part 41 and the support seat 43 can be configured to be detachably assembled and combined. Thereby, it is possible to facilitate separate sterilization of the needle part 41.

[0187] In some examples, a male-female mechanical fitting structure can be provided on the inner wall of the moving body 20 and the outer wall of the puncturing member 40. In some examples, the moving body 20 can include a fifth engaging feature 29, and the puncturing member 40 can include a sixth engaging feature 46 (see Figure 18 and Figure 19 ). The male-female mechanical fitting structure can be formed by the cooperation of the fifth engaging feature 29 and the sixth engaging feature 46. In some examples, the male-female mechanical fitting structure can be a concave-convex fitting structure. In some examples, the fifth engaging feature 29 can be one or more rib-shaped protrusions provided on the inner wall of the moving body 20, and the sixth engaging feature 46 can be one or more rib-shaped grooves provided on the outer wall of the puncturing member 40 (see Figure 18 and Figure 19 ). In some examples, when the puncturing member 40 is assembled to the moving body 20, one or more rib-shaped protrusions of the moving body 20 can be respectively embedded in one or more rib-shaped grooves of the puncturing member 40. In this case, on the one hand, through the matching of the rib-shaped protrusions and the rib-shaped grooves, it is possible to facilitate the assembly of the moving body 20 and the puncturing member 40; on the other hand, through the rib-shaped protrusions and the rib-shaped grooves, it is also possible to guide the direction when the puncturing member 40 and the moving body 20 move relative to each other; in addition, through the cooperation of the rib-shaped protrusions and the rib-shaped grooves, it is also possible to help prevent the puncturing member 40 from rotating undesirably. In some examples, the plurality of rib-shaped protrusions provided on the inner wall of the moving body 20 can be evenly or symmetrically distributed on the inner wall of the moving body 20.

[0188] In some examples, as described above, the piercing member 40 can be releasably held by the moving body 20. In some examples, the moving body 20 can include a second holding portion 27 (see Figure 18 ). The second holding portion 27 can be configured to releasably hold the piercing member 40. In some examples, the second holding portion 27 can be formed on the side wall 22 of the moving body 20. In some examples, the second holding portion 27 can be a notch formed on the side wall 22 of the moving body 20 (see Figure 19 ).

[0189] In some examples, the piercing member 40 can include a second locking portion 45. The second locking portion 45 can be configured to be releasably interlocked with the second holding portion 27. Thus, the piercing member 40 can be releasably held by the second holding portion 27 through the cooperation of the second locking portion 45 and the second holding portion 27. In some examples, the second locking portion 45 can be provided on the support base 43 of the piercing member 40.

[0190] In some examples, the second locking portion 45 can include an arm 450 (hereinafter referred to as the fourth arm 450) that extends substantially along the direction of the central axis CA, and a protrusion 451 (hereinafter referred to as the fourth protrusion 451) that is linked with the fourth arm 450 and protrudes substantially along a direction orthogonal to the central axis CA and away from the central axis CA. In this case, when the piercing member 40 is placed in the hollow portion 26 of the moving body 20, the second locking portion 45 is lapped with the notch of the moving body 20, so that the piercing member 40 can be held with a simplified structure.

[0191] In some examples, the fourth arm 450 can be elastic in a direction substantially orthogonal to the central axis CA. In some examples, when the piercing member 40 is held, the fourth protrusion 451 can pass through the notch. In this case, by lapping the fourth protrusion 451 with the notch of the moving body 20, the second locking portion 45 can be held with a simplified structure.

[0192] In some examples, the second holding portion 27 can include a first notch 271 and a second notch 272 that extend substantially along the central axis CA and are interconnected (see Figure 18 ). The first notch 271 can be close to the proximal end 101, and the second notch 272 can be close to the distal end 102. In some examples, the widths of the first notch 271 and the second notch 272 can be different. In some examples, the width of the first notch 271 can be greater than the width of the second notch 272.

[0193] In some examples, the first incision 271 may have a surface facing the proximal end 101. In some examples, the fourth protrusion 451 may have a surface facing the distal end 102. When the puncturing member 40 is held in the second holding portion 27, the surface of the fourth protrusion 451 facing the distal end 102 overlaps with the surface of the first incision 271 facing the proximal end 101.

[0194] In some examples, when an action is applied to the fourth arm 450 in a direction substantially orthogonal to the central axis CA, the fourth arm 450 may pivot. For example, when an action is applied to the fourth arm 450 in a direction substantially orthogonal to the central axis CA and toward the central axis CA, the fourth arm 450 may deflect so that one end of the fourth arm 450 near the distal end 102 moves in the direction of the central axis CA. When the fourth arm 450 deflects toward the central axis CA until the second locking portion 45 separates from the second holding portion 27, the puncturing member 40 may be released. Thus, the puncturing member 40 can be released with simple operation.

[0195] In some examples, when the puncturing member 40 is released, the arm of the second locking portion 45 may be squeezed toward the central axis CA. Thus, the second locking portion 45 can be released with simple operation. In some examples, the second holding portion 27 and the second locking portion 45 may be releasably interlocked by at least one of a buckle, a hook, a latch, or a pin. Thus, a releasable interlocking method can be provided.

[0196] In some examples, the second locking portion 45 of the puncturing member 40 may be formed as a shoulder structure (see in conjunction with Figure 18 、 Figure 18 and Figure 18 ). In some examples, along the central axis CA and in the direction toward the distal end 102, the fourth arm 450 may gradually move away from the central axis CA. In some examples, when projected along the central axis CA, the projection surface of the fourth protrusion 451 and the projection surface of the first incision 271 may wholly or partially coincide. In some examples, the number of the second locking portions 45 may be one or more, such as 1, 2, 3, or 4. In some examples, the number of the second locking portions 45 may be the same as the number of the second holding portions 27. In some examples, the width of the surface of the fourth protrusion 451 facing the distal end 102 may be smaller than the width of the first incision 271 and may be larger than the width of the second incision 272.

[0197] In some examples, the second housing 30 may include a second trigger portion 37 (see Figure 19 、 Figure 20 and Figure 11)。The second trigger portion 37 can be configured to enable the second holding portion 27 to be separated from the second locking portion 45 to release the puncturing member 40. Thus, the release of the moving body 20 can be facilitated by the second trigger portion 37. In some examples, the second trigger portion 37 can apply an action towards the central axis CA to the second locking portion 45 to squeeze the second locking portion 45 inward, so that the second locking portion 45 is separated from the second holding portion 27. In some examples, when the moving body 20 and the puncturing member 40 move towards the proximal end 101 to a predetermined position, the second locking portion 45 can be disengaged from the second holding portion 27, so that the puncturing member 40 is released. Thus, the release of the puncturing member 40 can be automatically triggered after the moving body 20 and the puncturing member 40 move to the predetermined position, which helps to more precisely control the timing of the puncturing member 40 leaving the host. Among them, the predetermined position can be the position where the monitoring device 800 has been applied to the surface of the host. In some examples, the predetermined position can also be the position where the implanting portion 81 of the sensor 8 has been introduced into the predetermined depth under the skin of the host by the puncturing member 40. That is, in some examples, the puncturing member 40 can be configured to be released after moving a predetermined distance relative to the second housing 30.

[0198] In some examples, the second trigger portion 37 can be formed on the inner wall of the second housing 30. In some examples, the second trigger portion 37 can be a protrusion (hereinafter referred to as the fifth protrusion) formed on the inner wall of the second housing 30 and protruding towards the central axis CA along a direction substantially orthogonal to the central axis CA. When the moving body 20 and the puncturing member 40 move relative to the second housing 30 (i.e., when the moving body 20 and the puncturing member 40 move towards the proximal end 101), the second locking portion 45 first moves to a position in contact with the second trigger portion 37. During the process of the moving body 20 and the puncturing member 40 continuing to move towards the proximal end 101, the fifth protrusion can abut against the fourth protrusion 451 and continuously apply an action towards the central axis CA to the fourth protrusion 451. When the moving body 20 and the puncturing member 40 move to the predetermined position, the fourth arm 450 retracts inward to separate the fourth protrusion 451 from the second holding portion 27, so that the puncturing member 40 is released.

[0199] Hereinafter, the cooperation of the second holding portion 27, the second locking portion 45 and the second trigger portion 37 will be described again. When the puncturing member 40 is held by the second holding portion 27, the second locking portion 45 is in contact with the second holding portion 27, and the second holding portion 27 can limit the movement of the second locking portion 45 towards the distal end 102 to hold the puncturing member 40 (see Figure 16) When the moving body 20 and the puncturing member 40 move toward the proximal end 101, the second locking portion 45 can first move to a position in contact with the second triggering portion 37. During the process that the moving body 20 and the puncturing member 40 continue to move toward the proximal end 101, the fifth protrusion can abut against the fourth protrusion 451 and continuously apply a force toward the central axis CA to the fourth protrusion 451. When the moving body 20 and the puncturing member 40 move to a predetermined position, the fourth arm 450 folds inward so that the fourth protrusion 451 is separated from the second holding portion 27, thereby releasing the puncturing member 40.

[0200] In some examples, after the puncturing member 40 is released by the moving body 20, the second driving portion 52 drives the puncturing member 40 toward the distal end 102 so that the puncturing member 40 leaves the host. In some examples, the retracted puncturing member 40 can be entirely located within the internal space of the first housing 10. In this case, it is possible to prevent the sharp needle portion 41 from being exposed outside the application device 100, improving the safety of the application device 100.

[0201] In some examples, as described above, the moving body 20 can include a receiving portion 21. In some examples, the receiving portion 21 can be provided at one end of the moving body 20 facing the proximal end 101, and the entrance of the receiving portion 21 can face the proximal end 101 (see Figure 20 ). In this case, it is convenient to install the monitoring device 800 into the receiving portion 21.

[0202] In some examples, the receiving portion 21 can include a constraining portion 210 for constraining the monitoring device 800 (see Figure 20 ). In this case, by constraining the monitoring device 800 accommodated in the receiving portion 21 through the constraining portion 210, the monitoring device 800 can be more firmly accommodated.

[0203] In some examples, the constraining portion 210 can include a constraining arm 211 and a protruding portion 212 that approaches the central axis CA along a direction substantially orthogonal to the central axis CA (see Figure 19 ). Among them, the constraining arm 211 can extend along the direction of the central axis CA. In some examples, the constraining arm 211 can be elastic. In some examples, the constraining arm 211 can approach the central axis CA. In this case, the constraining portion 210 can constrain the monitoring device 800 whose contour size is smaller than that of the receiving portion 21. For example, the electronic component 9 of the monitoring device 800 can be embedded inside the receiving portion 21, and an interference fit is formed between the constraining portion 210 and the outer shell 91 of the electronic component 9. In some examples, the number of the constraining portions 210 can be one or more, such as 1, 2, 3, or 4. In some examples, the constraining portions 210 can be evenly distributed along the outer periphery of the receiving portion 21.

[0204] Figure 19 It is a schematic diagram showing the sealing assembly 93 and the applicator cap 6 involved in the examples of the present disclosure.

[0205] In some examples, the application device 100 may include an applicator cap 6 (see Figure 19 ). In some examples, the applicator cap 6 may be detachably assembled to the first housing 10. When the applicator cap 6 is assembled to the first housing 10, the second housing 30 may be located in the sealed accommodation space formed by the applicator cap 6 and the first housing 10. In this case, a sealed space can be formed through the cooperation of the applicator cap 6 and the first housing 10 to protect the internal structure, and the second housing 30 located in the sealed space can inhibit the occurrence of unwanted accidental touches, improving the reliability of the application device 100.

[0206] In some examples, the applicator cap 6 can be removed from the first housing 10 to make the application device 100 in an applicable state. In some examples, as described above, the monitoring device 800 may include the sealing assembly 93 of the sealing sensor 8. In some examples, the applicator cap 6 can be removed from the first housing 10 and the sealing assembly 93 can be removed from the monitoring device 800 to make the application device 100 in an applicable state.

[0207] In some examples, the applicator cap 6 and the first housing 10 may be threadedly connected. Specifically, an external thread may be provided on the outer periphery of the end of the first housing 10 close to the host, and an internal thread matching the external thread may be provided on the inner wall of the applicator cap 6. Thereby, it is possible to facilitate the disassembly and assembly of the applicator cap 6 and the first housing 10. In some examples, the applicator cap 6 can be rotated in a predetermined direction to be removed from the first housing 10 and can be rotated in a direction opposite to the predetermined direction to be assembled to the first housing 10. In some examples, the predetermined direction may be the clockwise direction or the counterclockwise direction.

[0208] In some examples, the sealing assembly 93 may include a first engagement feature 930, and the applicator cap 6 may include a second engagement feature 61 (see Figure 21 ). The cooperation of the first engagement feature 930 and the second engagement feature 61 can make the sealing assembly 93 follow the rotation of the applicator cap 6 when the applicator cap 6 rotates in the first direction and the sealing assembly 93 does not move when the applicator cap 6 rotates in the second direction opposite to the first direction. In this case, it is possible to remove the sealing assembly 93 simultaneously while removing the applicator cap 6 by rotating the applicator cap 6 in the first direction, thus facilitating use; and during the assembly process of rotating the applicator cap 6 in the second direction to assemble the applicator cap 6 to the first housing 10, the sealing state of the sealing assembly 93 will not be affected, thus facilitating the factory assembly of the application device 100 and the monitoring device 800.

[0209] Figure 9 It is a schematic structural diagram of the inclined groove involved in the examples of the present disclosure. Among them, Figure 21 It is a schematic diagram projected along the direction of the central axis CA of the application device 100. In order to more clearly show the cooperation between the sealing component 93 and the applicator cap 6, some components and lines that may cause occlusion and misunderstanding are omitted.

[0210] In some examples, the first engagement feature 930 may be an inclined groove formed on the side wall of the sealing component 93 (see Figure 22 ). Among them, the inclined groove may have a limiting surface 931 and an inclined surface 932 that is transitionally connected to the side wall of the sealing component 93. The second engagement feature 61 may be a protrusion 62 (which may be referred to as the sixth protrusion 62) that matches the inclined groove (see Figure 22 and Figure 22 ). When the applicator cap 6 rotates in the first direction, the sixth protrusion 62 may abut against the limiting surface 931 to cause the sealing component 93 to rotate following the applicator cap 6; when the applicator cap 6 rotates in the second direction opposite to the first direction, the sixth protrusion 62 may slide along the inclined surface 932 and the outer periphery of the side wall of the sealing component 93. Thus, the cooperation between the first engagement feature 930 and the second engagement feature 61 can achieve the aforementioned preset function.

[0211] See Figure 21 , in the example of Figure 22 , the direction C1 schematically represents the clockwise direction, and the direction C2 schematically represents the counterclockwise direction (i.e., the direction opposite to the direction C1). When the applicator cap 6 rotates in the direction C1, the sixth protrusion 62 of the applicator cap 6 may abut against the limiting surface 931. When the applicator cap 6 rotates in the direction C2, the sixth protrusion 62 of the applicator cap 6 may slide along the inclined surface 932 and the outer periphery of the side wall of the sealing component 93.

[0212] In some examples, the applicator cap 6 may include a fourth limiting portion 63 (see Figure 22 Figure 22 Figure 21 ). The fourth limiting portion 63 may limit the position of the sealing component 93. In some examples, the fourth limiting portion 63 may limit the sealing component 93 in a manner of surrounding the outer periphery of the sealing component 93. Thus, it can help to inhibit the undesired shaking of the sealing component 93 and the monitoring device 800 in the first housing 10. In some examples, the sealing component 93 may also be referred to as a sensor cap.

[0213] In some examples, the fourth limiting portion 63 may include an arm (which may be referred to as the fifth arm) extending along the direction of the central axis CA. In some examples, the second engagement feature 61 may be formed on the fourth limiting portion 63. Thus, it can facilitate the engagement between the second engagement feature 61 and the first engagement feature 930 when the sealing component 93 is limited by the fourth limiting portion 63.

[0214] In some examples, after removing the applicator cap 6, the monitoring device 800 can be conveniently applied to the host by means of the applying device 100. In some examples, a desiccant can be provided in the sealed accommodation space formed by the applicator cap 6 and the first housing 10. Thereby, it can help to form a dry environment within the applying device 100, which is beneficial to the preservation of the monitoring device 800.

[0215] Now, the application process of the applying device 100 will be described again: Applying the monitoring device 800 to the host by means of the applying device 100 can include an application stage and a retraction stage. In the application stage, the applying device 100 can be applied to the host; in the retraction stage, the puncturing member 40 can leave the host.

[0216] First, remove the applicator cap 6 from the first housing 10 to make the applying device 100 enter the applicable state.

[0217] In the application stage, by placing the applying device 100 on the body surface of the host, the proximal surface 31 of the second housing 30 is brought into contact with the body surface of the host, and then the first housing 10 is pressed towards the host. When the first trigger portion 33 moves to the first locking portion 23, the first trigger portion 33 actuates the first locking portion 23 to pivot in a direction towards the central axis CA, so that the first locking portion 23 is separated from the first holding portion 12, thereby releasing the moving body 20; then, the first driving portion 51 (or by means of human force) acts on the moving body 20 in a direction towards the proximal end 101, causing the moving body 20 and the puncturing member 40 to move together towards the proximal end 101. The monitoring device 800 located in the accommodating portion 21 can be pushed onto the body surface of the host, and under the action of the puncturing member 40, the sensor 8 is at least partially placed under the skin of the host.

[0218] In the retraction stage, as the moving body 20 and the puncturing member 40 move towards the proximal end 101, the second trigger portion 37 provided on the inner wall of the second housing 30 contacts the second locking portion 45 of the puncturing member 40. The second trigger portion 37 actuates the second locking portion 45 to deflect in a direction towards the central axis CA, so that the second locking portion 45 is separated from the second holding portion 27, thereby releasing the puncturing member 40; then, the second driving portion 52 (or by means of human force) acts on the puncturing member 40 in a direction towards the distal end 102, causing the puncturing member 40 to move towards the distal end 102 and leave the host.

[0219] In addition, it should be noted that in the retraction stage, the first driving part 51 (or with the help of human power) can still act on the moving body 20 towards the proximal end 101. In other words, for the first driving part 51 configured as an elastic component (for example, a spring), when the moving body 20 is driven towards the host and the monitoring device 800 accommodated in the receiving part 21 has been applied to the body surface of the host, the first driving part 51 can still be in an energy storage state. In this case, in the retraction stage, the monitoring device 800 is closely attached to the body surface of the host under the action of the first driving part 51, thereby effectively reducing the possibility that the monitoring device 800 is separated from the host due to the influence of the puncturing member 40 and the sensor 8 during the retraction stage.

[0220] In summary, according to the present disclosure, an application device 100 and an analyte monitoring system 1000 that are easy to operate and can accurately apply the monitoring device 800 to the host can be provided.

[0221] Although the present disclosure has been specifically described above in conjunction with the accompanying drawings and embodiments, it can be understood that the above description does not limit the present disclosure in any form. Those skilled in the art can make deformations and changes to the present disclosure as needed without departing from the essence and scope of the present disclosure, and these deformations and changes all fall within the scope of the present disclosure.

Claims

1. An application device for applying a monitoring device to a host, characterized in that: The application device includes a first housing, a second housing, a driving mechanism, a moving body, a puncture member provided on the moving body, and a proximal end close to the host and a distal end away from the host during operation. The first housing includes a first retaining portion for releasably retaining the moving body, and the second housing has a proximal surface that contacts the skin of the host during operation. The moving body includes a receiving portion for accommodating the monitoring device, and the puncture member is configured to at least partially introduce the monitoring device into the host's subcutaneous tissue. The first shell and the second shell move relative to each other in a manner of approaching each other to release the holding of the moving body by the first holding portion. After the moving body is released, it moves toward the proximal end together with the puncture member under the action of the driving mechanism to apply the monitoring device to the host and at least partially locate it under the host's skin.

2. The application device according to claim 1, characterized in that The moving body includes a first locking portion configured to be releasably interlocked with the first retaining portion, and the second housing includes a first triggering portion capable of separating the first retaining portion from the first locking portion to release the moving body.

3. The application device according to claim 2, characterized in that When the first housing and the second housing move relatively along the direction of the central axis of the applying device, the first triggering portion acts on the first locking portion to separate the first locking portion from the first retaining portion.

4. The application device according to claim 3, characterized in that The first retaining portion is a convex structure formed on the inner wall of the first shell. When the moving body is retained on the first retaining portion, the first locking portion engages with the convex structure; the first triggering portion deflects the first locking portion in a direction away from the first retaining portion to separate the first locking portion from the first retaining portion.

5. The application device according to claim 1 or 2, characterized in that The first housing includes a first restricting portion configured to inhibit the second housing from being detached from the first housing, and the second housing includes a first restricting portion coupled to the first restricting portion.

6. The application device according to claim 5, characterized in that The first shell includes a second limiting portion configured to inhibit the second shell from moving toward the proximal end. After the first shell and the second shell move relative to each other and release the moving body, the second shell is restricted by the second limiting portion.

7. The application device according to claim 6, characterized in that The first limiting portion and the second limiting portion are adjacently arranged in a direction along the central axis of the applying device, and the first limiting portion is configured to cooperate with the second limiting portion to hold the second shell.

8. The application device according to claim 1 or 2, characterized in that The driving mechanism includes a first driving part and a second driving part, and the moving body includes a second holding part that releasably holds the puncture member. After the moving body and the puncture member move toward the proximal end to a predetermined position under the action of the first driving part, the second holding part releases the puncture member, and the puncture member moves toward the distal end under the action of the second driving part.

9. The application device according to claim 8, characterized in that The first driving part is an elastic element, and two ends of the first driving part are respectively in contact with the first shell and the moving body. When the moving body is held by the first holding part, the first driving part is in a compressed state.

10. The application device according to claim 8, characterized in that The second driving part is an elastic element, and two ends of the second driving part are respectively in contact with the moving body and the puncture member. When the puncture member is held in the second holding part, the second driving part is in a compressed state.

11. The application device according to claim 1, characterized in that The application device includes an applicator cover detachably assembled to the first housing. When the applicator cover is assembled to the first housing, the second housing is located in a sealed accommodation space formed by the applicator cover and the first housing.

12. The application device according to claim 11, characterized in that The monitoring device includes a sensor that can be partially placed under the host's skin, an electronic component coupled to the sensor, and a sealing component that seals the sensor. The applicator cover is coupled to the sealing component. When the applicator cover is removed from the first shell, the sealing component is removed together with the applicator cover to enable the application device to be in an applicable state.

13. The application device according to claim 12, characterized in that The sealing assembly has a first engagement feature, and the applicator cover includes a second engagement feature. The first engagement feature cooperates with the second engagement feature so that the sealing assembly follows the applicator cover when the applicator cover rotates in a first direction, and the sealing assembly does not move when the applicator cover rotates in a second direction opposite to the first direction.

14. An analyte monitoring system, characterized in that The invention comprises the application device according to any one of claims 1 to 13, and a monitoring device.

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