Pill particle grinding and forming device for medicine production and processing

Abstract

The invention relates to the technical field of medicine production, and particularly discloses a pill particle grinding and forming device for medicine production and processing. The grinding disc is arranged at the top end of the base; the number of the material boxes is two, and the two material boxes are placed on the front side and the rear side of the top end of the base correspondingly. The first motor is in screw connection with the top middle of the base; the first rotating rod is locked to the output end of the first motor through a coupler, and the top end of the first rotating rod rotationally extends out of the top end of the grinding disc. And the supporting frame fixedly sleeves the middle part of the outer wall of the first rotating rod. The device can prevent high temperature from being generated in the grinding process, avoid the adverse effect of the high temperature on heat-sensitive medicinal materials, accurately adjust the grinding strength, ensure the moderate granularity of medicine particles, cannot damage crystal structures or molecular arrangement of the medicine, cannot cause loss of effective components, improves the quality and stability of the medicine, and improves the quality of the medicine. And the curative effect and the safety of the medicine are also ensured.

Description

Technical Field

[0001] The invention relates to the technical field of pharmaceutical production, in particular to a pill particle grinding and forming device used in pharmaceutical production and processing. Background Art

[0002] In the field of pharmaceutical production and processing, the production of pill granules is a complex and delicate process, usually including key steps such as raw material preparation, mixing, granulation, drying, and subsequent grinding and molding. Among them, the grinding process is crucial to ensuring the quality, uniformity and efficacy of pill granules. This is because grinding can crush the raw materials to an appropriate particle size, which not only facilitates the uniform mixing of drug ingredients, but also promotes the dissolution and release of drugs in the body, thereby improving the drug's absorption rate and bioavailability. Especially for some Chinese herbal medicines, the active ingredients they contain, such as volatile oils, alkaloids, flavonoids, etc., may be difficult to fully release if they are not fully ground, which may affect the efficacy. Therefore, in pharmaceutical production and processing, it has become a common practice to use electric grinders to grind pill particles. Electric grinders use high-speed rotating grinding parts to apply mechanical force to the material particles, causing them to collide and rub against each other, thereby achieving the purpose of crushing. This method is highly efficient and can quickly grind pill particles to the required particle size. However, the electric grinders in the prior art have obvious limitations when running at high speeds. Due to the intense friction and collision between the material particles, a large amount of heat is generated, forming a high-temperature environment. This high temperature is particularly detrimental to heat-sensitive medicinal herbs. For example, Chinese medicinal materials containing volatile oils, such as mint, have volatile oil components that tend to evaporate quickly at high temperatures, causing the medicinal materials to lose some of their therapeutic effects. At the same time, high temperatures may also trigger enzymatic reactions in the Chinese medicinal materials, accelerating their degradation and further reducing their efficacy. More seriously, the medicinal properties of some Chinese medicines are closely related to their temperature. Excessively high temperatures may cause their medicinal properties to change dramatically and even produce toxic substances. For example, realgar can be oxidized into highly toxic arsenic after heating, which shows that temperature control is crucial to ensuring drug safety. In addition, the active ingredients of herbs such as ginseng and astragalus are saponins, which are sensitive to temperature and cannot withstand high temperatures. During the grinding process, if the heating time is too long or the temperature is too high, the saponins may be destroyed, thereby affecting the efficacy. On the other hand, electric grinders also have deficiencies in their control over grinding force. For certain drugs with specific structures, such as itraconazole, fluoxetine hydrochloride, norfloxacin, and carbamazepine, excessive grinding force may destroy their crystal structure or molecular arrangement, thereby affecting the solubility and stability of the drug. If the grinding force is too small, the pill particles cannot be effectively ground to the required particle size, which will also affect the quality of the drug. In addition, the grinding force directly affects the particle size distribution of the powder, which is one of the important factors determining the performance of the drug. If the particle size is too large, the particles of the medicinal material may not be fully mixed and released, affecting the absorption rate and bioavailability of the drug. Excessive grinding may lead to excessive loss of the active ingredients of the medicinal material. For example, active ingredients such as alkaloids and flavonoids are destroyed or volatilized during the grinding process, thereby reducing the efficacy of the drug. Summary of the Invention

[0003] The purpose of the present invention is to solve the shortcomings of the prior art that the temperature is too high and the grinding force cannot be controlled, and a pill particle grinding and molding device for pharmaceutical production and processing is proposed.

[0004] To achieve the above-mentioned objectives, the present invention provides the following technical solutions: A pill particle grinding and forming device for pharmaceutical production and processing, comprising: a base; a grinding disc arranged at the top of the base; two material boxes, which are respectively placed on the front and rear sides of the top of the base; a first motor screwed to the middle of the top of the base; a first rotating rod locked to the output end of the first motor through a coupling, and the top of the first rotating rod can be rotatably extended out of the top of the grinding disc; a support frame fixedly sleeved on the middle of the outer wall of the first rotating rod; mixing mechanisms are respectively arranged on the outer walls of the support frame; and a grinding mechanism is arranged at the top of the first rotating rod.

[0005] Preferably, the grinding mechanism includes: a second support plate, the middle part of the bottom end of the second support plate is arranged at the top end of the first rotating rod; the number of first limit rods is four, and the four first limit rods are grouped in twos and divided into two groups, and the outer walls of the two groups of first limit rods are slidably adapted and inserted into the front and rear sides of the second support plate; the number of pressing plates is two, and the front and rear sides of the top ends of the two pressing plates are respectively arranged at the bottom ends of the four first limit rods; the number of second limit rods is four, and the outer walls of the four second limit rods are slidably adapted and inserted into the front and rear sides of the two pressing plates; the number of mounting racks is two, and the front and rear sides of the top ends of the two mounting racks are respectively arranged at the bottom ends of the four second limit rods; the front and rear ends of the pressure roller are rotatably arranged at the front and rear sides of the inner cavity of the mounting rack through bearings, and the pressure roller is located in the inner cavity of the grinding disc, and the bottom end of the pressure roller contacts the bottom end of the inner cavity of the grinding disc.

[0006] The top end of the fourth rotating rod is clamped on the top of the first supporting plate, and the top end of the fourth rotating rod is clamped on the top of the third motor.

[0007] Preferably, in order to stir the mixed material, the mixing mechanism includes: a first support plate, the number of the first support plates is two, and the two first support plates are respectively arranged on the left and right sides of the support frame; a connecting block is arranged on the outside of the bottom end of the first support plate; the number of sliders is eight, and the eight sliders are respectively arranged on the upper and lower ends of the front and rear sides of the two connecting blocks; the number of brushes is four, and the upper and lower ends of the inner sides of the four brushes are provided with slide grooves along the left and right directions, and the sliders can be slidably adapted and inserted into the inner cavity of the slide groove corresponding to their positions, and the four brushes are grouped in pairs and divided into two groups, and the two brushes in each group are staggered, and the bottom ends of the brushes are in contact with the bottom end of the inner cavity of the grinding disc; the left and right ends of the guide rod are respectively arranged on the left and right sides of the inner cavity of the slide groove, and the slider can be slidably sleeved on the outer wall of the guide rod.

[0008] The transmission gears are connected with the drive gear of the driving member, and the transmission gears are connected with the transmission gear of the driving member, and the transmission gears are connected with the transmission gear of the driving member.

[0009] Preferably, in order to turn over the material at the bottom end of the inner cavity of the grinding disk, the pill particle grinding and forming device for pharmaceutical production and processing also includes: a first connecting rod, the number of the first connecting rods is two, and the two first connecting rods are respectively arranged on the left and right sides of the bottom end of the support frame; the top end of the scraper is rotatably sleeved on the outer wall of the first connecting rod, and the bottom end of the scraper is in contact with the bottom end of the inner cavity of the grinding disk; the first torsion spring is sleeved on the middle part of the outer wall of the first connecting rod, one end of the first torsion spring is clamped on the outer wall of the scraper, and the other end of the first torsion spring is clamped on the outer wall of the support frame.

[0010] Preferably, in order to encourage the material to gather in the middle of the inner cavity of the grinding disc, the pill particle grinding and forming device for pharmaceutical production and processing also includes: a second connecting rod, the number of the second connecting rods is four, the four second connecting rods are grouped in twos, and are divided into two groups, and the top ends of the two groups of second connecting rods are respectively arranged on the front and rear sides of the bottom end of the support frame; the guide plate is rotatably sleeved on the outer wall of the second connecting rod, the two guide plates in each group are arranged opposite to each other, and the outer wall of the guide plate is in contact with the inner wall of the grinding disc; the number of baffles is two, and the two baffles are respectively arranged on the front and rear sides of the bottom end of the support frame; the second torsion spring is sleeved on the middle part of the outer wall of the second connecting rod, one end of the second torsion spring is clamped on the outer wall of the guide plate, and the other end of the second torsion spring is clamped on the outer wall of the baffle.

[0011] Preferably, a plurality of filter holes are provided at the bottom end of the inner cavity of the grinding disc.

[0012] Compared with the prior art, the present invention has the following beneficial effects: (1) The present invention can place the material into the inner cavity of the grinding disc, and the second support plate and the support frame can be driven to rotate by the first motor and the first rotating rod. The rotation of the second support plate can drive the pressure roller to move circumferentially along the inner cavity of the grinding disc, so that the material in the inner cavity of the grinding disc can be squeezed, ground and crushed by the circumferentially moving pressure roller.

[0013] (2) The present invention can drive the fourth rotating rod to rotate by starting the third motor. The rotation of the fourth rotating rod can drive the first sprocket to drive the rotating drum to rotate through the second sprocket and the chain. The rotational force generated by the rotation can drive the screw to drive the pressure plate to move up and down, thereby adjusting the extrusion degree of the spring, and further adjusting the pressure applied by the pressure roller to the material.

[0014] (3) The present invention can drive the first support plate to rotate through the support frame, drive the scraper and the guide plate to move in the circumferential direction, and use the first torsion spring to ensure that the bottom end of the scraper is always in contact with the bottom end of the inner cavity of the grinding disc, so that the scraper can be used to turn over the material at the bottom end of the inner cavity of the grinding disc, and the second torsion spring can ensure that the guide plate is always in contact with the inner wall of the grinding disc, so that the guide plate can be used to gather the material in the inner cavity of the grinding disc to the middle, and then the pressure roller can be used to grind the material. The rotation of the first support plate can drive the brush to move in the circumferential direction, so that the brush can be used to stir and mix the material in the inner cavity of the grinding disc, ensuring the smooth operation of the material. The grinding effect can be ensured, and the second motor can be used to drive the sliding column to move circumferentially through the third rotating rod and the connecting plate, and then the sliding column moving along the circumferential direction can be used to cooperate with the driving plate to drive the rack located at the rear side to reciprocate left and right. The left and right reciprocating motion of the rack located at the rear side can be driven by the gear to move in the opposite direction to the rack located at the front side, so that the rack can be used to drive the brush to reciprocate left and right, thereby enhancing the stirring and mixing effect of the brush on the material, and under the stirring and mixing effect of the brush, the material with qualified particle size after grinding will be prompted to fall into the inner cavity of the material box through the filter hole for collection.

[0015] (4) This device can prevent the generation of high temperatures during the grinding process, thus avoiding the adverse effects of high temperatures on heat-sensitive medicinal materials. At the same time, it can precisely adjust the grinding force to ensure that the particle size of the drug particles is moderate, without destroying the crystal structure or molecular arrangement of the drug, nor causing the loss of active ingredients. This not only improves the quality and stability of the drug, but also ensures the efficacy and safety of the drug. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0017] Figure 1 It is a schematic diagram of the structure of the present invention; Figure 2 An exploded view of the present invention; Figure 3 is a structural diagram of the support frame; Figure 4 Schematic diagram of the structure of the grinding mechanism; Figure 5 This is the exploded view of the support frame; Figure 6 This is an exploded diagram of the hybrid mechanism; Figure 7 This is an exploded view of the grinding mechanism; Figure 8 for Figure 2 A magnified view of point A; Figure 9 for Figure 5 Enlarged view of point B; Figure 10 for Figure 5 Enlarged view of point C; Figure 11 for Figure 6 Enlarged view of point D.

[0018] The components represented by the reference numerals in the figure are as follows: 1. Base; 2. Grinding disc; 3. Filter hole; 4. Material box; 5. First motor; 6. First rotating rod; 7. Support frame; 8. Mixing mechanism; 81. First supporting plate; 82. Connecting block; 83. Slider; 84. Brush; 85. Slide; 86. Guide rod; 87. Rack; 88. Second rotating rod; 89. Gear; 810. Drive plate; 811. Second motor; 812. Third rotating rod; 813. Connecting plate; 814. Sliding column; 9. Grinding mechanism; 91. Second supporting plate; 92. Rotating drum; 93. Screw; 94. Pressing plate; 95. First limiting rod; 96. Second limiting rod; 97. Mounting frame; 98. Pressing roller; 99. Spring; 910. First sprocket; 911. Fourth rotating rod; 912. Second sprocket; 913. Third motor; 914. Chain; 10. First connecting rod; 11. Scraper; 12. First torsion spring; 13. Second connecting rod; 14. Guide plate; 15. Second torsion spring; 16. Baffle. DETAILED DESCRIPTION

[0019] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts shall fall within the scope of protection of the present invention.

[0020] Reference Figures 1-11, a pill particle grinding and forming device for pharmaceutical production and processing, comprising: a base 1, a grinding disc 2, a filter hole 3, a material box 4, a first motor 5, a first rotating rod 6, a support frame 7, a mixing mechanism 8, a grinding mechanism 9, a first connecting rod 10, a scraper 11, a first torsion spring 12, a second connecting rod 13, a guide plate 14, a second torsion spring 15 and a baffle 16, the grinding disc 2 is arranged at the top of the base 1, and a plurality of filter holes 3 are opened at the bottom end of the inner cavity of the grinding disc 2. After grinding, the material with qualified particle size will pass through the filter holes 3 and fall into the inner cavity of the material box 4. There are two material boxes 4, which are respectively placed on the front and back sides of the top of the base 1. The material box 4 is used to store and collect the ground material. The first motor 5 is screwed to the middle of the top of the base 1. The machine 5 is of prior art. The first motor 5 is a servo motor. The first motor 5 is connected to a servo controller. No further details will be given here. The first motor 5 is used to drive the first rotating rod 6 to rotate. The first rotating rod 6 is locked at the output end of the first motor 5 through a coupling. The top of the first rotating rod 6 can rotatably extend out of the top of the grinding disc 2. The first rotating rod 6 is used to drive the support frame 7 and the second support plate 91 to rotate. The support frame 7 is fixedly sleeved on the middle of the outer wall of the first rotating rod 6. The support frame 7 is used to drive the scraper 11, the guide plate 14 and the first support plate 81 to move circumferentially. The mixing mechanisms 8 are respectively arranged on the outer walls of the support frame 7. The mixing mechanism 8 is used to stir and mix the materials in the inner cavity of the grinding disc 2. The grinding mechanism 9 is arranged on the top of the first rotating rod 6. The grinding mechanism 9 is used to grind the material in the inner cavity of the grinding disc 2. There are two first connecting rods 10. The two first connecting rods 10 are respectively arranged on the left and right sides of the bottom end of the support frame 7. The first connecting rod 10 is used to support the scraper 11. The top of the scraper 11 is rotatably sleeved on the outer wall of the first connecting rod 10. The bottom end of the scraper 11 contacts the bottom end of the inner cavity of the grinding disc 2. The scraper 11 is used to turn over the material at the bottom end of the inner cavity of the grinding disc 2. The first torsion spring 12 is sleeved on the middle part of the outer wall of the first connecting rod 10. One end of the first torsion spring 12 is clamped on the outer wall of the scraper 11, and the other end of the first torsion spring 12 is clamped on the outer wall of the support frame 7. The first torsion spring 12 is elastically deformed after being squeezed or stretched by external force, and returns to its initial state after the external force is removed. The torsion spring 12 is used here to urge the scraper 11 to always contact the bottom end of the inner cavity of the grinding disc 2. The number of the second connecting rods 13 is four, and the four second connecting rods 13 are grouped in twos, divided into two groups. The top ends of the two groups of second connecting rods 13 are respectively arranged on the front and rear sides of the bottom end of the support frame 7. The second connecting rod 13 is used to support the guide plate 14, and the guide plate 14 is rotatably sleeved on the outer wall of the second connecting rod 13. The two guide plates 14 in each group are arranged opposite to each other, and the outer wall of the guide plate 14 is in contact with the inner wall of the grinding disc 2. The guide plate 14 is used to bring the material in the inner cavity of the grinding disc 2 closer to the middle. The number of the baffles 16 is two, and the two baffles 16 are respectively arranged on the front and rear sides of the bottom end of the support frame 7. The second torsion spring 15 is sleeved on the middle part of the outer wall of the second connecting rod 13.One end of the second torsion spring 15 is clamped to the outer wall of the guide plate 14, and the other end of the second torsion spring 15 is clamped to the outer wall of the baffle 16. The second torsion spring 15 undergoes elastic deformation when squeezed or stretched by an external force, and returns to its original state after the external force is removed. The second torsion spring 15 is used to ensure that the guide plate 14 is always in contact with the inner wall of the grinding disc 2.

[0021] Specifically, the grinding mechanism 9 includes: a second support plate 91, a rotating drum 92, a screw 93, a pressing plate 94, a first limiting rod 95, a second limiting rod 96, a mounting frame 97, a pressure roller 98, a spring 99, a first sprocket 910, a fourth rotating rod 911, a second sprocket 912, a third motor 913 and a chain 914. The middle part of the bottom end of the second support plate 91 is arranged at the top end of the first rotating rod 6. There are four first limiting rods 95, and the four first limiting rods 95 are grouped in pairs and divided into two groups. The outer walls of the two groups of first limiting rods 95 are respectively slidably adapted and plugged into the front and rear sides of the second support plate 91. There are two pressing plates 94, and the front and rear sides of the top ends of the two pressing plates 94 are respectively arranged at the bottom ends of the four first limiting rods 95. The pressure plate 94 is used to squeeze the spring 99 to produce elastic deformation. There are four second limit rods 96. The outer walls of the four second limit rods 96 are slidably adapted to be inserted into the front and rear sides of the two pressure plates 94. There are two mounting frames 97. The front and rear sides of the top ends of the two mounting frames 97 are respectively arranged at the bottom ends of the four second limit rods 96. The mounting frame 97 is used to install a pressure roller 98. The front and rear ends of the pressure roller 98 are respectively rotatably arranged on the front and rear sides of the inner cavity of the mounting frame 97 through bearings. The pressure roller 98 is located in the inner cavity of the grinding disc 2. The bottom end of the pressure roller 98 contacts the bottom end of the inner cavity of the grinding disc 2. The pressure roller 98 is used to squeeze the material in the inner cavity of the grinding disc 2. There are two rotating drums 92. The two rotating drums 92 are respectively rotatably arranged through bearings The rotation force generated by the rotation of the drum 92 on the front and rear sides of the top of the second support plate 91 can prompt the screw 93 to push the pressure plate 94 to move. The screw 93 is screwed to the inner cavity of the drum 92, and the bottom end of the screw 93 can slidably extend out of the bottom end of the second support plate 91. The bottom end of the screw 93 is set in the middle of the top of the pressure plate 94. The spring 99 is sleeved on the outer wall of the second limit rod 96. The bottom end of the spring 99 is clamped on the top of the mounting bracket 97. The top end of the spring 99 is clamped on the bottom end of the pressure plate 94. The spring 99 is a rotating spring. It undergoes elastic deformation after being squeezed or stretched by external force and returns to its initial state after the external force is removed. The spring 99 is used here to push the pressure roller 98 downward, thereby applying pressure to the material in the inner cavity of the grinding disc 2. The first sprocket 91 0 is sleeved on the outer wall of the rotating drum 92 and locked by a top screw. The bottom end of the fourth rotating rod 911 is rotatably arranged on the middle part of the left side of the top of the second support plate 91 through a bearing. The second sprocket 912 is sleeved on the outer wall of the fourth rotating rod 911 and locked by a top screw. The chain 914 is sleeved on the outer walls of the two first sprockets 910 and the second sprocket 912. The third motor 913 is screwed to the top of the second support plate 91. The top of the fourth rotating rod 911 is locked to the output end of the third motor 913 through a coupling. The third motor 913 is a prior art. The third motor 913 is a servo motor. The third motor 913 is connected to a servo controller. I will not go into details here. The third motor 913 is used here to drive the second sprocket 912 to rotate.

[0022] Specifically, the mixing mechanism 8 includes: a first support plate 81, a connecting block 82, a slider 83, a brush 84, a slide 85, a guide rod 86, a rack 87, a second rotating rod 88, a gear 89, a driving plate 810, a second motor 811, a third rotating rod 812, a connecting plate 813 and a slide column 814. There are two first support plates 81, which are respectively arranged on the left and right sides of the support frame 7. The connecting block 82 is arranged on the outer side of the bottom end of the first support plate 81. There are eight sliders 83, which are respectively arranged on the front and rear sides and the upper and lower ends of the two connecting blocks 82. The connection block 82 and the brush 84 can be moved by the cooperation between the slider 83 and the slide 85. The four brushes 84 are connected together, and the number of brushes 84 is four. The upper and lower ends of the inner sides of the four brushes 84 are provided with a slide groove 85 along the left and right directions. The slider 83 can be slidably adapted and inserted into the inner cavity of the slide groove 85 corresponding to its position. The four brushes 84 are grouped in pairs and divided into two groups. The two brushes 84 in each group are staggered. The bottom end of the brush 84 contacts the bottom end of the inner cavity of the grinding disc 2. The brush 84 is used to stir and mix the material in the inner cavity of the grinding disc 2. The left and right ends of the guide rod 86 are respectively arranged on the left and right sides of the inner cavity of the slide groove 85. The slider 83 can be slidably sleeved on the outer wall of the guide rod 86. The guide rod 86 can prevent the slider 83 from escaping from the inner cavity of the slide groove 85. The rack 87 is arranged on the brush At the top of 84, four racks 87 are grouped in pairs and divided into two groups. The two racks 87 in each group are arranged relative to each other and staggered. The racks 87 are used to drive the brush 84 to move. The bottom end of the second rotating rod 88 is rotatably set at the middle of the top of the connecting block 82 through a bearing. The gear 89 is sleeved on the outer wall of the second rotating rod 88 and locked by a top screw. The gear 89 and the rack 87 are engaged. There are two drive plates 810. The rear sides of the bottom ends of the two drive plates 810 are respectively set at the top ends of the two racks 87 located on the rear side. The second motor 811 is screwed to the top of the first support plate 81. The second motor 811 is a prior art and is a servo motor. The second motor 811 is connected to a servo controller, which will not be described in detail here. The second motor 811 is used to drive the connecting plate 813 to rotate. The top of the third rotating rod 812 is locked to the output end of the second motor 811 through a coupling. The bottom end of the third rotating rod 812 can be rotatably extended from the bottom end of the first support plate 81. The inner side of the top of the connecting plate 813 is arranged at the bottom end of the third rotating rod 812, and the sliding column 814 is arranged on the outer side of the bottom end of the connecting plate 813. The two sliding columns 814 can be slidably adapted and plugged into the middle of the inner cavity of the two driving plates 810 respectively. The cooperation between the sliding column 814 and the driving plate 810 can drive the rack 87 located on the rear side to perform reciprocating motion back and forth.

[0023] Here's how it works: When in use, the squeezing force of the pressing roller 98 is adjusted according to the ground material, and the third motor 913 is started. The rotation of the output end of the third motor 913 can drive the second sprocket 912 to rotate through the fourth rotating rod 911. The rotation of the second sprocket 912 can drive the two first sprockets 910 to drive the rotating drum 92 to rotate through the chain 914. The rotational force generated by the rotation of the rotating drum 92 can drive the screw 93 to drive the pressure plate 94 to move up and down. The up and down movement of the pressure plate 94 can adjust the squeezing degree of the spring 99, and then the thrust applied by the spring 99 to the mounting frame 97 can be adjusted. , until the pressure plate 94 is adjusted to a suitable position, the material to be ground is poured into the inner cavity of the grinding disc 2, and the first motor 5 and the second motor 811 are started. The output end rotation of the first motor 5 can drive the support frame 7 and the second support plate 91 to rotate through the first rotating rod 6. The rotation of the support frame 7 can drive the scraper 11, the guide plate 14 and the first support plate 81 to rotate with the first rotating rod 6 as the center of the circle. The output end rotation of the second motor 811 can drive the connecting plate 813 to rotate through the third rotating rod 812. The rotation of the connecting plate 813 can drive the sliding column 814 to rotate with the first rotating rod 6 as the center of the circle. The third rotating rod 812 rotates as the center of the circle, and the sliding column 814 rotates with the third rotating rod 812 as the center of the circle, and can cooperate with the driving plate 810 to drive the rack 87 at the rear side to move back and forth left and right. The left and right reciprocating motion of the rack 87 at the rear side can cooperate with the gear 89 to drive the rack 87 at the front side to move in the opposite direction, so that the rack 87 can drive the brush 84 to move back and forth left and right. The rotation of the second support plate 91 can drive the pressure roller 98 to move circumferentially. The circumferential motion of the guide plate 14 can gather the material in the inner cavity of the grinding disc 2 to the middle, so as to The pressure roller 98 that performs circumferential motion can squeeze and grind the material in the inner cavity of the grinding disc 2, the scraper 11 that performs circumferential motion can turn over the material, and the brush 84 that performs reciprocating motion can stir and mix the material. As the brush 84 stirs and mixes the material, the material with a qualified particle size after grinding can be swept into the inner cavity of the filter hole 3 and dropped into the inner cavity of the material box 4 for collection. At the same time, as the pressure roller 98 squeezes and grinds the material for a longer time, the third motor 913 is started in time to adjust the grinding force applied by the pressure roller 98 to the material, thereby ensuring the grinding effect of the material.

[0024] In summary, this device can prevent the generation of high temperatures during the grinding process, avoiding the adverse effects of high temperatures on heat-sensitive medicinal materials. At the same time, it can accurately adjust the grinding force to ensure that the particle size of the drug particles is moderate, which will neither destroy the crystal structure or molecular arrangement of the drug nor cause the loss of active ingredients. This not only improves the quality and stability of the drug, but also ensures the efficacy and safety of the drug.

[0025] The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. These preferred embodiments do not exhaustively describe all details, nor do they limit the present invention to specific embodiments. Obviously, many modifications and variations are possible based on the contents of this specification. These embodiments are selected and described in detail in this specification to better explain the principles and practical applications of the present invention, thereby enabling those skilled in the art to better understand and utilize the present invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A pill particle grinding and forming device for pharmaceutical production and processing, characterized in that: include: Base (1); A grinding disc (2), the grinding disc (2) being arranged on the top of the base (1); Material boxes (4), the number of the material boxes (4) is two, and the two material boxes (4) are respectively placed on the front and rear sides of the top of the base (1); A first motor (5), the first motor (5) being screw-connected to the middle of the top end of the base (1); a first rotating rod (6), the first rotating rod (6) being locked to the output end of the first motor (5) via a coupling, and the top end of the first rotating rod (6) being rotatably extended out of the top end of the grinding disc (2); A support frame (7), the support frame (7) being fixedly sleeved on the middle portion of the outer wall of the first rotating rod (6); Mixing mechanisms (8), the mixing mechanisms (8) being respectively arranged on the outer walls of the support frames (7); A grinding mechanism (9), wherein the grinding mechanism (9) is arranged at the top end of the first rotating rod (6).

2. The pill particle grinding and forming device for pharmaceutical production and processing according to claim 1, characterized in that: The grinding mechanism (9) comprises: a second support plate (91), wherein the middle portion of the bottom end of the second support plate (91) is arranged at the top end of the first rotating rod (6); First limiting rods (95), the number of the first limiting rods (95) is four, and the four first limiting rods (95) are grouped in pairs, divided into two groups, and the outer walls of the two groups of the first limiting rods (95) are respectively slidably adapted to be plugged into the front and rear sides of the second support plate (91); A pressure plate (94), wherein the number of the pressure plates (94) is two, and the front and rear sides of the top ends of the two pressure plates (94) are respectively arranged at the bottom ends of the four first limiting rods (95); Second limiting rods (96), the number of the second limiting rods (96) is four, and the outer walls of the four second limiting rods (96) are respectively slidably adapted to be plugged into the front and rear sides of the two pressing plates (94); A mounting frame (97), wherein the number of the mounting frames (97) is two, and the front and rear sides of the top ends of the two mounting frames (97) are respectively arranged at the bottom ends of the four second limiting rods (96); A pressure roller (98), wherein the front and rear ends of the pressure roller (98) are rotatably arranged on the front and rear sides of the inner cavity of the mounting frame (97) through bearings, respectively. The pressure roller (98) is located in the inner cavity of the grinding disc (2), and the bottom end of the pressure roller (98) is in contact with the bottom end of the inner cavity of the grinding disc (2).

3. The pill particle grinding and forming device for pharmaceutical production and processing according to claim 2, characterized in that: The grinding mechanism (9) further comprises: A rotating drum (92), wherein the number of the rotating drums (92) is two, and the two rotating drums (92) are rotatably arranged on the front and rear sides of the top end of the second support plate (91) via bearings; A screw rod (93), the screw rod (93) being screwed to the inner cavity of the rotating drum (92), the bottom end of the screw rod (93) being slidably extended out of the bottom end of the second support plate (91), and the bottom end of the screw rod (93) being arranged at the middle of the top end of the pressing plate (94); A spring (99), wherein the spring (99) is sleeved on the outer wall of the second limiting rod (96), the bottom end of the spring (99) is clamped on the top end of the mounting frame (97), and the top end of the spring (99) is clamped on the bottom end of the pressure plate (94); a first sprocket (910), the first sprocket (910) being sleeved on the outer wall of the rotating drum (92) and locked by a top screw; a fourth rotating rod (911), the bottom end of the fourth rotating rod (911) being rotatably disposed at the middle portion of the left side of the top end of the second supporting plate (91) via a bearing; A second sprocket (912), the second sprocket (912) is sleeved on the outer wall of the fourth rotating rod (911) and locked by a top screw; A chain (914), wherein the chain (914) is sleeved on the outer walls of the two first sprockets (910) and the second sprocket (912); A third motor (913) is screwed to the top of the second support plate (91), and the top of the fourth rotating rod (911) is locked to the output end of the third motor (913) through a coupling.

4. The pill particle grinding and forming device for pharmaceutical production and processing according to claim 3, characterized in that: The mixing mechanism (8) comprises: A first support plate (81), wherein the number of the first support plates (81) is two, and the two first support plates (81) are respectively arranged on the left and right sides of the support frame (7); A connecting block (82), the connecting block (82) being arranged on the outer side of the bottom end of the first support plate (81); Slide blocks (83), the number of the slide blocks (83) is eight, and the eight slide blocks (83) are respectively arranged at the front and rear sides and the upper and lower ends of the two connecting blocks (82); Brushes (84), the number of the brushes (84) is four, the inner sides of the four brushes (84) are provided with slide grooves (85) along the left and right directions at both upper and lower ends, the sliders (83) are slidably adapted to be plugged into the inner cavity of the slide grooves (85) corresponding to their positions, the four brushes (84) are grouped in pairs, and are divided into two groups, the two brushes (84) in each group are staggered, and the bottom ends of the brushes (84) are in contact with the bottom end of the inner cavity of the grinding disc (2); A guide rod (86), wherein the left and right ends of the guide rod (86) are respectively arranged on the left and right sides of the inner cavity of the slide groove (85), and the slider (83) is slidably sleeved on the outer wall of the guide rod (86).

5. The pill particle grinding and forming device for pharmaceutical production and processing according to claim 4, characterized in that: The mixing mechanism (8) further comprises: Racks (87), the racks (87) are arranged at the top of the brush (84), and the four racks (87) are grouped in pairs, divided into two groups, and the two racks (87) in each group are arranged opposite to each other and staggered; a second rotating rod (88), the bottom end of the second rotating rod (88) being rotatably disposed at the middle portion of the top end of the connecting block (82) via a bearing; A gear (89), wherein the gear (89) is sleeved on the outer wall of the second rotating rod (88) and is locked by a top screw, and the gear (89) is meshed with the rack (87); A driving plate (810), wherein the number of the driving plates (810) is two, and the rear sides of the bottom ends of the two driving plates (810) are respectively arranged on the top ends of the two racks (87) located at the rear side; a second motor (811), the second motor (811) being screw-connected to the top end of the first support plate (81); a third rotating rod (812), the top end of the third rotating rod (812) being locked to the output end of the second motor (811) via a coupling, and the bottom end of the third rotating rod (812) being rotatably extended from the bottom end of the first support plate (81); a connecting plate (813), wherein the inner side of the top end of the connecting plate (813) is arranged at the bottom end of the third rotating rod (812); The sliding column (814) is arranged on the outer side of the bottom end of the connecting plate (813), and the two sliding columns (814) are respectively slidably adapted to be plugged into the middle of the inner cavity of the two driving plates (810).

6. The pill particle grinding and forming device for pharmaceutical production and processing according to claim 5, characterized in that: The pill particle grinding and forming device for pharmaceutical production and processing also includes: A first connecting rod (10), wherein the number of the first connecting rods (10) is two, and the two first connecting rods (10) are respectively arranged on the left and right sides of the bottom end of the support frame (7); A scraper (11), the top end of the scraper (11) is rotatably sleeved on the outer wall of the first connecting rod (10), and the bottom end of the scraper (11) is in contact with the bottom end of the inner cavity of the grinding disc (2); A first torsion spring (12), wherein the first torsion spring (12) is sleeved on the middle portion of the outer wall of the first connecting rod (10), one end of the first torsion spring (12) is clamped on the outer wall of the scraper (11), and the other end of the first torsion spring (12) is clamped on the outer wall of the support frame (7).

7. The pill particle grinding and forming device for pharmaceutical production and processing according to claim 6, characterized in that: The pill particle grinding and forming device for pharmaceutical production and processing also includes: Second connecting rods (13), the number of the second connecting rods (13) is four, and the four second connecting rods (13) are grouped in pairs, divided into two groups, and the top ends of the two groups of second connecting rods (13) are respectively arranged at the front and rear sides of the bottom end of the support frame (7); A guide plate (14), the guide plate (14) being rotatably sleeved on the outer wall of the second connecting rod (13), the two guide plates (14) in each group being arranged opposite to each other, and the outer wall of the guide plate (14) being in contact with the inner wall of the grinding disc (2); baffles (16), the number of the baffles (16) is two, and the two baffles (16) are respectively arranged at the front and rear sides of the bottom end of the support frame (7); A second torsion spring (15), wherein the second torsion spring (15) is sleeved on the middle portion of the outer wall of the second connecting rod (13), one end of the second torsion spring (15) is clamped on the outer wall of the guide plate (14), and the other end of the second torsion spring (15) is clamped on the outer wall of the baffle (16).

8. The pill particle grinding and forming device for pharmaceutical production and processing according to claim 7, characterized in that: A plurality of filter holes (3) are provided at the bottom end of the inner cavity of the grinding disc (2).

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