Traditional Chinese medicine composition for treating urinary tract infection of cats in healthy manner and preparation method of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition for treating urinary tract infection in a healthy manner for cats and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials: dandelion, cape jasmine, coix seeds, white mulberry root-bark, sea-buckthorn and liquorice. The preparation method comprises the following steps: decocting and extracting with steam, combining filtrate and concentrating under reduced pressure to obtain traditional Chinese medicine extract; aiming at a clinical common frequently-occurring disease of cat urinary tract infection, the traditional Chinese medicine is mainly used for clearing heat, promoting diuresis and treating stranguria, has the effects of tonifying kidney, nourishing yin, tonifying qi and strengthening body resistance, and treats both symptoms and root causes, and is clinically proved to be capable of quickly relieving symptoms and improving the living quality of cats; the invention fills the blank of clearing heat and promoting diuresis and tonifying kidney and nourishing yin in the traditional Chinese medicine compound for treating urinary tract infection of cats, and the preparation ingeniously integrates the characteristics of Tibetan medicine, Mongolian medicine and Chinese and original traditional Chinese medicines, and embodies the application of multi-ethnic medicine wisdom in treating urinary tract infection diseases of cats.

Description

Technical Field

[0001] The present invention belongs to the technical field of pet medicine, and particularly relates to a traditional Chinese medicine composition for the treatment of urinary tract infection in cats and a preparation method thereof. Background Art

[0002] Traditional Chinese Medicine (TCM) theory categorizes urinary tract infections (UTIs) in cats as "gonadism," primarily caused by damp-heat accumulation in the lower abdomen, leading to bladder dysfunction and urinary obstruction. However, current treatments for UTIs in pets primarily rely on Western antibiotics, which pose a risk of drug resistance. Traditional Chinese veterinary prescriptions, on the other hand, focus on clearing heat and dampness, lacking comprehensive treatment options for combined kidney and qi-yin deficiency syndromes. Summary of the Invention

[0003] One of the purposes of the present invention is to provide a Chinese medicine composition for the treatment of urinary tract infection in cats; The second object of the present invention is to provide a method for preparing the Chinese medicine composition for treating urinary tract infection in cats.

[0004] In order to achieve the above object, the technical solution adopted by the present invention is: A traditional Chinese medicine composition for the treatment of urinary tract infection in cats is prepared from the following raw materials in parts by weight: 20-50 parts of dandelion, 10-30 parts of gardenia, 10-50 parts of coix seed, 50-100 parts of mulberry bark, 1-30 parts of sea buckthorn, and 1-30 parts of liquorice.

[0005] Preferably, the herb is prepared from the following raw materials in the following weight proportions: 30-50 parts of dandelion, 15-30 parts of gardenia, 25-50 parts of coix seed, 50-100 parts of mulberry bark, 10-30 parts of sea buckthorn and 9-30 parts of liquorice.

[0006] A traditional Chinese medicine composition for the treatment of urinary tract infection in cats is prepared from the following raw materials in parts by weight: 30-50 parts of dandelion, 10-30 parts of gardenia, 10-50 parts of coix seed, 50-100 parts of mulberry bark, 1-30 parts of sea buckthorn, 1-30 parts of liquorice, 1-30 parts of rhodiola rosea, 1-30 parts of polygonatum, and 10-30 parts of privet fruit.

[0007] Preferably, the medicine is made from the following raw materials in the following weight ratio: 40 parts of dandelion, 25 parts of gardenia, 30 parts of coix seed, 70 parts of mulberry bark, 10 parts of sea buckthorn, 10 parts of liquorice, 25 parts of rhodiola, 20 parts of polygonatum and 30 parts of privet fruit.

[0008] A method for preparing a Chinese medicine composition for treating urinary tract infection in cats, comprising the following steps: S1. Take the selected weight portions of raw materials and place them in a multifunctional extraction tank. Add 8-12 times the weight of water and soak for 30 minutes. Steam heat to boiling and maintain boiling state for the first decoction for 1 hour. S2. After the first decoction is completed, filter to obtain filtrate I, add 6-10 times the weight of water to the filter residue, steam heat to boiling, maintain boiling state and perform a second decoction for 1 hour; S3. After the second decoction is completed, filter to obtain filtrate II, and combine filtrate I and filtrate II; S4. Transfer the combined filtrate obtained in S3 to a vacuum concentration tank, and concentrate under reduced pressure at 60° C.-70° C. to obtain a Chinese medicine extract when the relative density reaches 1.15-1.25.

[0009] The principle and explanation of the prescription of the present invention: 1. Principle of formula: This formula cleverly combines the characteristics of Tibetan medicine, Mongolian medicine and traditional Chinese medicine from the Central Plains, reflecting the wisdom of using multi-ethnic medicine to treat cat-related urinary tract infections.

[0010] Seabuckthorn, a treasure of Tibetan medicine, is a unique medicinal and edible plant native to the Qinghai-Tibet Plateau. The Tibetan medical classic "Four Medical Classics" records that it "clears heat from the viscera and invigorates qi and blood." It is sour and astringent in taste, warm and neutral in nature, and enters the spleen, stomach, lung, and heart meridians. Seabuckthorn fruit is rich in vitamins, flavonoids, polyphenols and other active ingredients, and has the effects of diuresis, anti-inflammatory and antibacterial, spleen-strengthening and digestion-promoting, and blood circulation and blood stasis. The "Chinese Materia Medica" records that it can clear heat and relieve cough, clear the stomach and increase appetite, reduce adverse reactions and stop vomiting, dry dampness and eliminate phlegm, promote diuresis and dampness, soften the liver and reduce swelling, cool blood and lower blood pressure, and relieve asthma and calm the mind. Seabuckthorn has unique therapeutic effects on damp-heat or blood-related diseases, such as fever-induced cough, stomach heat, poor appetite, and dysuria. Rhodiola rosea, a sacred medicine for the plateau, is a traditional Tibetan anti-hypoxia medicine used by Mongolian medicine to restore vitality. It tastes sweet and bitter, is neutral in nature, and enters the lung and heart meridians. Rhodiola rosea mainly contains active ingredients such as salidroside, salidroside aglycone, and salidroside. It has multiple effects such as invigorating qi and promoting blood circulation, dredges meridians and relieves asthma, anti-fatigue, anti-hypoxia, anti-aging, anti-inflammatory, anti-tumor, anti-peroxidation, and antioxidant. Modern research has confirmed that Rhodiola rosea can exert its pharmacological effects by regulating cell signaling pathways and enhancing cellular energy metabolism. In particular, in terms of immune regulation, it can promote lymphocyte proliferation, enhance macrophage phagocytosis, and increase natural killer cell activity. Coix seed, known as the "Pearl of Coix" in Zhuang areas, is sweet, light, and cool in nature, entering the spleen, stomach, and lung meridians. Coix seed has the effects of promoting diuresis and dispelling dampness, strengthening the spleen and stopping diarrhea, removing numbness, draining pus, and detoxifying and dispersing nodules. Master of Traditional Chinese Medicine Zhang Qi, inspired by the formula of Yiyifuzibaijiangsan in the Synopsis of the Golden Chamber, believed that its pathogenesis was basically the same as that of chronic urinary tract infection, and used coix seed to treat chronic urinary tract infection with good results. Coix seed is sweet and light in nature, can dispel dampness, and its cold properties can clear heat. It is often used to treat symptoms such as edema, frequent urination, urgency, and pain caused by damp-heat. Polygonatum sibiricum is a traditional medicine used by the Tujia ethnic minority. Polygonatum multiflorum is recorded as "Dragon Cup Seven" in Tujia Medicine. It has a sweet taste and a neutral nature, and enters the spleen, lung, and kidney meridians. Polygonatum sibiricum has the effects of tonifying qi and nourishing yin, strengthening the spleen, moistening the lungs, and benefiting the kidneys. The Compendium of Materia Medica records that Polygonatum sibiricum can "tonify the five internal organs, calm the mind, grow muscles, replenish qi and blood, and strengthen tendons and bones." Polygonatum sibiricum complements Ligustrum lucidum fruit in tonifying qi and nourishing yin, jointly enhancing the kidney-tonifying and strengthening effects. It is suitable for patients with persistent urinary tract infections and insufficient vital energy. Ligustrum lucidum fruit, sweet and bitter in flavor, cool in nature, enters the liver and kidney meridians; it nourishes the liver and kidneys, improves eyesight and darkens hair, and clears away heat and detoxifies; Ligustrum lucidum fruit is often combined with Eclipta prostrata to form Erzhi Pills, which nourish the liver and kidneys, nourish yin and stop bleeding; the combination of the two can enhance the kidney-tonifying and yin-nourishing effects and is used to treat symptoms such as urinary tract infections with bleeding and kidney yin deficiency. Gardenia, bitter in taste and cold in nature, enters the Heart, Lung, and Triple Burner meridians. Gardenia has the effects of purging heat and relieving restlessness, clearing heat and removing dampness, cooling blood and detoxifying. The Compendium of Materia Medica states that Gardenia can "clear the triple burner fire, purge damp-heat, relieve stagnant heat, clear the stomach, and stop bleeding." Gardenia has significant heat-clearing and damp-removing effects and is often used to treat stranguria and dysuria caused by damp-heat. Dandelion, one of the three flowers of Mongolian medicine, is a core ingredient in the Mongolian medicine's "Three Flower Soup for Clearing Heat and Detoxifying," and is commonly used by grassland peoples as an anti-inflammatory. It has a sweet and bitter taste and a cold nature, entering the liver and stomach meridians. Dandelion has the effects of clearing heat and detoxifying, reducing swelling and dispersing stagnation, and acting as a diuretic and relieving stranguria. Modern research shows that dandelion contains multiple active ingredients with antibacterial and anti-inflammatory properties, including inhibitory effects on common urogenital pathogens such as Escherichia coli and Staphylococcus. Drinking dandelion tea can increase water intake, produce more urine, flush the bladder and urethra, and promote the excretion of inflammation. Morus alba bark, a specialty Miao medicine, is a common herbal remedy for damp-heat stranguria among the Miao people. It is sweet in flavor, cold in nature, and enters the lung and spleen meridians. It has the effects of purging the lungs and relieving asthma, promoting diuresis, and reducing swelling. The Compendium of Materia Medica states that mulberry bark can "drain lung fire and promote diuresis." Its diuretic and swelling-reducing effects can promote the excretion of excess water and improve symptoms of urinary dysfunction. Clinical studies have shown that mulberry bark has a stranguria-relieving effect when used to treat urinary system-related diseases such as polyuria and edema. Licorice root is sweet in taste and neutral in nature. It enters the heart, lung, spleen and stomach meridians. Licorice root has the effects of tonifying the spleen and replenishing qi, clearing away heat and detoxifying, removing phlegm and relieving cough, relieving acute pain and harmonizing various medicines. The Compendium of Materia Medica records that licorice root can "harmonize various medicines, detoxify and clear away heat". In prescriptions, licorice root mainly plays the role of harmonizing various medicines, relieving acute pain and also has certain heat-clearing and detoxifying effects.

[0011] 2. Explanation: Based on the theory of monarch, minister, assistant and envoy combined with the characteristics of ethnic minority medicine, the formula is deeply analyzed to highlight the compatibility logic for treating feline urinary tract infections: Dandelion and Gardenia are the main herbs in the prescription, which play the leading role in clearing away heat and dampness, detoxifying and relieving stranguria. Dandelion has outstanding heat-clearing and detoxifying effects, can directly reduce heat toxins, and clear away damp-heat in the lower abdomen. Modern pharmacological studies have shown that dandelion contains active ingredients such as taraxasterol and taraxacin, which have broad-spectrum antibacterial effects and have significant inhibitory effects on common urinary tract infection pathogens such as Escherichia coli and Staphylococcus aureus. In clinical practice, dandelion is often used to treat urinary tract infections such as hot stranguria and hematuria. Its heat-clearing and detoxifying effects can effectively relieve symptoms such as urinary pain and urgency; Gardenia is cold in nature and bitter in taste, and enters the heart, lung, and triple burner meridians, with the effects of purging fire and relieving restlessness, clearing heat and dampness, cooling blood and detoxifying; Gardenia can clear the triple burner fire, especially the damp heat in the lower burner, so that damp heat can be eliminated through urination; "Compendium of Materia Medica" records that Gardenia "clears the triple burner fire, purges damp heat, and relieves stagnant heat"; Gardenia and Taraxacum can be used together to enhance the effects of clearing heat and dampness, detoxifying and relieving stranguria, and together they play the role of the monarch drug; Coix seed, mulberry bark, sea buckthorn, and Ligustrum lucidum fruit are the assistant herbs in the prescription, assisting the main herbs in promoting diuresis, relieving stranguria, clearing heat and nourishing yin; Coix seed is cool in nature and sweet in taste, and enters the spleen, stomach, and lung meridians, and has the effects of promoting diuresis and eliminating dampness, strengthening the spleen and stopping diarrhea; Coix seed can both promote diuresis and strengthen the body in the treatment of chronic urinary tract infections, and complements the tonic effects of Polygonatum sibiricum and Ligustrum lucidum fruit; Coix seed, combined with dandelion and gardenia, can enhance the effects of clearing heat and dampness, relieving stranguria, while not damaging yin and blood; Morus alba is cold in nature and sweet in taste, and enters the lung and spleen meridians, and has the effects of purging the lungs and relieving asthma, promoting diuresis and reducing swelling The combination of mulberry bark and gardenia can enhance the effects of clearing heat and dampness, promoting diuresis and relieving stranguria, and promote the excretion of damp heat through urination; sea buckthorn is warm in nature, sour and astringent in taste, and enters the spleen, stomach, lung, and heart meridians, with diuretic and dampness-removing, anti-inflammatory and antibacterial effects; the combination of sea buckthorn and dandelion can enhance the effects of removing damp heat and anti-inflammatory, and also has the effect of strengthening the spleen and digestion; Ligustrum lucidum is cool in nature, sweet and bitter in taste, and enters the liver and kidney meridians, with the effects of nourishing the liver and kidney, improving eyesight and darkening hair; Ligustrum lucidum is used to treat urinary tract infections of the qi and yin deficiency type, can nourish the liver and kidney, enhance immunity, and prevent recurrence of the disease; Rhodiola rosea, Polygonatum sibiricum and Licorice are the adjuvants in the prescription, which play the role of replenishing Qi and activating blood circulation, nourishing Yin and replenishing Qi, and harmonizing various medicines; Rhodiola rosea is mild in nature, sweet and bitter in taste, and enters the lung and heart meridians, and has the effects of replenishing Qi and activating blood circulation, unblocking meridians and relieving asthma, resisting fatigue and resisting hypoxia; Rhodiola rosea can promote lymphocyte proliferation, enhance macrophage phagocytic function, and increase natural killer cell activity, and has an auxiliary improvement effect on the low immunity of patients with urinary tract infection; Rhodiola rosea and Polygonatum sibiricum are compatible, which can enhance the effect of replenishing Qi and nourishing Yin; Polygonatum sibiricum is mild in nature, sweet in taste, and enters the spleen, lung and kidney meridians, It has the effects of replenishing qi and nourishing yin, strengthening the spleen, moistening the lungs and benefiting the kidneys; Polygonatum sibiricum is used to treat urinary tract infection with dry stool, and has the effects of replenishing the kidney and activating blood circulation, moistening the intestines and relieving constipation; Polygonatum sibiricum is used in combination with Ligustrum lucidum fruit to enhance the effects of replenishing the kidney and nourishing yin, consolidating the foundation and nourishing the essence; Licorice is mild in nature and sweet in taste, and enters the heart, lung, spleen and stomach meridians. It has the effects of replenishing spleen and replenishing qi, clearing away heat and detoxifying, removing phlegm and relieving cough, relieving acute pain and harmonizing various medicines; Licorice is used in combination with the whole prescription medicine to alleviate the properties of the medicine, reduce the stimulation of cold medicines on the spleen and stomach, and at the same time has a certain heat-clearing and detoxifying effect.

[0012] The beneficial effects of the present invention compared to the prior art are: The present invention solves the acute damp-heat problem of urinary tract infection in cats through reasonable compatibility, and fundamentally regulates the cat's physique and prevents recurrence by nourishing the kidney and yin, replenishing qi and strengthening the body. Compared with the existing technology, the present invention has the following beneficial effects: 1. Combining attack and supplement, treating both the symptoms and the root cause: not only resolves the acute symptoms of damp-heat, but also strengthens the body's resistance and prevents recurrence by nourishing the kidney and yin, replenishing qi and strengthening the body's health; 2. Good palatability: specially designed for cats to easily accept the taste, improving compliance; 3. No drug resistance issues: Using natural plant ingredients avoids the risk of drug resistance and side effects caused by long-term use of antibiotics; 4. Scientific compatibility: Carefully combine the herbs according to their properties, flavors and meridian characteristics to ensure that the herbs can achieve the best synergistic effect and comprehensively enhance the therapeutic effect; The present invention provides a safe, effective and easily accepted traditional Chinese medicine solution for urinary tract infection in cats, and has significant clinical application value and market prospects.

[0013] This invention addresses urinary tract infections (UTIs) in cats, a common and frequently occurring clinical disease, by providing a compound preparation that primarily clears heat, promotes dampness removal, and relieves stranguria, while also tonifying the kidneys and nourishing yin, invigorating qi and strengthening the body's vital energy, achieving both a tackling effect and addressing both the underlying symptoms and the underlying cause. This invention fills a gap in traditional Chinese medicine formulas for treating urinary tract infections in cats that balance clearing heat, promoting dampness removal, and tonifying the kidneys and nourishing yin. This preparation cleverly integrates the characteristics of Tibetan, Mongolian, and traditional Chinese medicines from the Central Plains, embodying the application of multi-ethnic medical wisdom in the treatment of urinary tract infections in cats.

[0014] The Chinese medicine composition of the present invention is suitable for the following types of urinary tract infections: Acute damp-heat type: urinary frequency, urgency, pain, and burning sensation during urination. In this stage, the main treatment is to dispel pathogenic factors, clear away heat and dampness, and relieve stranguria. Chronic kidney deficiency with dampness type: urinary frequency, urgency, and repeated attacks, fatigue, and weakness. In this stage, the main treatment is to strengthen the body, tonify the kidney, nourish yin, and eliminate dampness. Qi and yin deficiency type: urinary frequency, urgency, pain, and dry mouth and tongue. In this stage, the main treatment is to invigorate qi and nourish yin, and clear away heat and eliminate dampness. Mixed deficiency and excess type: urinary symptoms include both damp-heat and kidney deficiency. In this stage, both attacking and tonifying are needed, with equal emphasis on clearing heat and dampness and tonifying the kidney and nourishing yin. Clinical applications have shown that the Chinese medicine composition of the present invention can not only quickly relieve symptoms but also improve the quality of life of cats.

[0015] The present invention comprises weighing Chinese herbs in proportion, decocting with water to extract the effective ingredients, filtering and concentrating the extract to form an extract, and then preparing an oral liquid with good palatability. The preparation has the effects of clearing away heat and dampness, relieving stranguria and detoxifying, tonifying the kidney and nourishing yin, and replenishing qi and strengthening the exterior. Clinical application has shown that it has significant therapeutic effects on cats with acute and chronic urinary tract infections, especially those with damp-heat combined with kidney deficiency and qi and yin deficiency. DETAILED DESCRIPTION

[0016] The present invention will be further described below in conjunction with specific embodiments.

[0017] Example 1 Dandelion 20g, Gardenia 10g, Coix seed 10g, Morus alba bark 50g, Sea buckthorn 1g and Licorice 1g.

[0018] Example 2 Dandelion 30g, Gardenia 15g, Coix seed 25g, Morus alba bark 50g, Sea buckthorn 10g and Licorice 9g.

[0019] Example 3 50g of dandelion, 30g of gardenia, 50g of coix seed, 100g of mulberry bark, 30g of sea buckthorn and 30g of licorice.

[0020] Example 4 50g of dandelion, 30g of gardenia, 25g of coix seed, 100g of mulberry bark, 10g of sea buckthorn and 30g of licorice.

[0021] Example 5 Dandelion 20g, Gardenia 15g, Coix seed 50g, Morus alba bark 50g, Sea buckthorn 30g and Licorice 9g.

[0022] Example 6 Dandelion 30g, Gardenia 10g, Coix seed 10g, Morus alba bark 50g, Sea buckthorn 1g, Licorice 1g, Rhodiola rosea 1g, Polygonatum 1g and Ligustrum lucidum fruit 10g.

[0023] Example 7 Dandelion 40g, Gardenia 25g, Coix seed 30g, Morus alba bark 70g, Sea buckthorn 10g, Licorice 10g, Rhodiola rosea 25g, Polygonatum 20g and Ligustrum lucidum fruit 30g.

[0024] Example 8 50g of dandelion, 30g of gardenia, 50g of coix seed, 100g of mulberry bark, 30g of sea buckthorn, 30g of licorice, 30g of rhodiola rosea, 30g of polygonatum and 30g of privet fruit.

[0025] Example 9 A method for preparing a Chinese medicine composition for treating urinary tract infection in cats, comprising the following steps: S1. Take the raw materials in Example 4 in parts by weight and place them in a multifunctional extraction tank. Add 8 times the weight of water and soak for 30 minutes. Steam heat to boiling and maintain boiling for the first decoction for 1 hour. S2. After the first decoction is completed, filter to obtain filtrate I, add 6 times the weight of water to the filter residue, steam heat to boiling, maintain boiling state and perform the second decoction for 1 hour; S3, after the second decoction is completed, filter to obtain filtrate II, and combine filtrate I and filtrate II; S4. Transfer the combined filtrate obtained in S3 to a vacuum concentration tank, and concentrate under reduced pressure at 60° C. to obtain a Chinese medicine extract when the relative density reaches 1.15-1.25.

[0026] Example 10 A method for preparing a Chinese medicine composition for treating urinary tract infection in cats, comprising the following steps: S1. Take the raw materials in Example 5 in parts by weight and place them in a multifunctional extraction tank. Add 10 times the weight of water and soak for 30 minutes. Steam heat to boiling and maintain boiling for the first decoction for 1 hour. S2. After the first decoction is completed, filter to obtain filtrate I, add 6 times the weight of water to the filter residue, steam heat to boiling, maintain boiling state and perform the second decoction for 1 hour; S3, after the second decoction is completed, filter to obtain filtrate II, and combine filtrate I and filtrate II; S4. Transfer the combined filtrate obtained in S3 to a vacuum concentration tank, and concentrate under reduced pressure at 65° C. to obtain a Chinese medicine extract when the relative density reaches 1.15-1.25.

[0027] Example 11 A method for preparing a Chinese medicine composition for treating urinary tract infection in cats, comprising the following steps: S1. Take the raw materials in Example 7 in parts by weight and place them in a multifunctional extraction tank. Add 12 times the weight of water and soak for 30 minutes. Steam heat to boiling and maintain boiling for the first decoction for 1 hour. S2. After the first decoction is completed, filter to obtain filtrate I, add 10 times the weight of water to the filter residue, steam heat to boiling, and maintain boiling state for the second decoction, decoction for 1 hour; S3, after the second decoction is completed, filter to obtain filtrate II, and combine filtrate I and filtrate II; S4. Transfer the combined filtrate obtained in S3 to a vacuum concentration tank, and concentrate under reduced pressure at 70° C. to obtain a Chinese medicine extract when the relative density reaches 1.15-1.25.

[0028] Clinical trials: Directions for use and recommended dosage: Directly drip into the mouth, 0.5-1 ml / kg body weight, twice daily. Continuous use is recommended for no less than 2 weeks, and can be extended to 4-6 weeks in chronic cases.

[0029] Clinical Case 1 Breed British Shorthair, color gray and white, male, cat age 4 years old, weight 6kg; Clinical diagnosis: acute urinary tract infection.

[0030] The raw materials of the formula are prepared in the same weight ratio as in Example 4 and the preparation method is adopted as in Example 9.

[0031] Treatment: In the acute stage, the focus is on clearing heat, promoting dampness and relieving stranguria. Use drugs such as dandelion, gardenia, coix seed, mulberry bark, and sea buckthorn to quickly eliminate damp heat and relieve symptoms such as frequent urination, urgency, and pain. Administer 5 ml of the drug twice a day, directly into the mouth each time.

[0032] According to the above physical and chemical index results, it can be seen from Table 1 that the cat in this case suffered from acute urinary tract infection. After two weeks of treatment with the Chinese medicine composition, its creatinine and urea nitrogen levels were significantly reduced to normal levels as shown in Table 2.

[0033] Clinical Case 2 Breed: British Shorthair, color: silver, male, age: 4 years, weight: 6.8 kg; Clinical diagnosis: urinary retention, post-renal renal injury, and hyperkalemia 3 days prior. After treatment, the patient is in poor condition during the recovery period.

[0034] The raw materials of the formula are prepared in the same weight ratio as in Example 5 and the preparation method is adopted as in Example 10.

[0035] Treatment: In the chronic stage, the focus is on tonifying the kidney and nourishing yin, invigorating qi and strengthening the body, and heavy use of sea buckthorn and coix seed to enhance the body's immunity and reduce recurrence; and a small amount of dandelion, gardenia and other heat-clearing and dampness-removing drugs to prevent the retention of pathogens. The drug is given twice a day, 5.5 ml each time, and dripped directly into the mouth.

[0036] Based on the above-mentioned physical and chemical indices, Tables 3 and 4 show that the cat in this case suffered from a series of urinary tract infections, including urinary retention, post-renal renal injury, and hyperkalemia. Catheterization and intravenous infusions were performed to restore water and electrolyte balance, promote urine production, and reduce the burden on the kidneys. Following treatment, the cat's physical and mental state remained poor during the recovery period, as shown in Table 4. After three weeks of treatment with the Chinese herbal composition of the present invention, blood glucose, creatinine, and urea nitrogen levels significantly decreased to normal levels, as shown in Table 5.

[0037] Clinical Case 3 The cat is a rural cat, black and white, neutered, 2 years old, and weighs 5 kg. Clinical diagnosis: urinary retention, poor condition after catheterization.

[0038] The raw materials of the formula are prepared in the weight proportions of Example 7 and the preparation method of Example 11 is adopted.

[0039] Treatment: For mixed deficiency and excess syndromes, a combined attack and tonification approach is needed to clear heat and dampness while tonifying the kidneys and nourishing yin, addressing both the symptoms and the root cause, improving efficacy. This prescription, composed of nine herbs: sea buckthorn, rhodiola rosea, coix seed, polygonatum, glossy privet fruit, gardenia, dandelion, mulberry bark, and liquorice, primarily focuses on clearing heat and dampness to relieve stranguria, while also tonifying the kidneys and nourishing yin, invigorating qi, and strengthening the body's balance. This formula combines attack and tonification, addressing both the symptoms and the root cause. Administer 3 ml twice daily, directly orally.

[0040] According to the above physical and chemical index results, it can be seen from Table 6 that the cat in this case suffered from urinary retention and was still in poor condition after catheterization. After four weeks of treatment with the Chinese medicine composition of the present invention, its blood sugar and alanine aminotransferase levels were significantly reduced, as can be seen from Table 7.

Claims

1. A Chinese medicine composition for treating urinary tract infection in cats, characterized in that: The invention is prepared from the following raw materials in proportions by weight: 20-50 parts of dandelion, 10-30 parts of gardenia, 10-50 parts of coix seed, 50-100 parts of mulberry bark, 1-30 parts of sea buckthorn and 1-30 parts of liquorice.

2. The Chinese medicine composition for treating urinary tract infection in cats according to claim 1, characterized in that: The invention is prepared from the following raw materials in proportion by weight: 30-50 parts of dandelion, 15-30 parts of gardenia, 25-50 parts of coix seed, 50-100 parts of mulberry bark, 10-30 parts of sea buckthorn and 9-30 parts of liquorice.

3. A Chinese medicine composition for treating urinary tract infection in cats, characterized in that: The invention is prepared from the following raw materials in proportions by weight: 30-50 parts of dandelion, 10-30 parts of gardenia, 10-50 parts of coix seed, 50-100 parts of mulberry bark, 1-30 parts of sea buckthorn, 1-30 parts of liquorice, 1-30 parts of rhodiola rosea, 1-30 parts of polygonatum and 10-30 parts of privet fruit.

4. The Chinese medicinal composition for treating urinary tract infection in cats according to claim 3, wherein The invention is prepared from the following raw materials in proportion by weight: 40 parts of dandelion, 25 parts of gardenia, 30 parts of coix seed, 70 parts of mulberry bark, 10 parts of sea buckthorn, 10 parts of liquorice, 25 parts of rhodiola, 20 parts of polygonatum and 30 parts of privet fruit.

5. A method for preparing the Chinese medicine composition according to any one of claims 1 to 4, characterized in that The steps include: S1. Take the selected weight portions of raw materials and place them in a multifunctional extraction tank. Add 8-12 times the weight of water and soak for 30 minutes. Steam heat to boiling and maintain boiling state for the first decoction for 1 hour. S2. After the first decoction is completed, filter to obtain filtrate I, add 6-10 times the weight of water to the filter residue, steam heat to boiling, maintain boiling state and perform a second decoction for 1 hour; S3, after the second decoction is completed, filter to obtain filtrate II, and combine filtrate I and filtrate II; S4. Transfer the combined filtrate obtained in S3 to a vacuum concentration tank, and concentrate under reduced pressure at 60° C.-70° C. to obtain a Chinese medicine extract when the relative density reaches 1.15-1.25.

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