Pharmacological laboratory auxiliary device and method in pharmacy

Abstract

The invention discloses a pharmacological laboratory auxiliary device and method in pharmacy, and relates to the technical field of pharmacological research assistance. A pharmacological laboratory auxiliary device in pharmacy comprises a base and a groove body fixedly installed at the top of the base, and further comprises a driving frame arranged on the base and a grinding wheel hinged to the driving frame, and the driving frame drives the grinding wheel to rotate in the groove body; the pressure adjusting assembly is arranged on the base; dynamic accurate control over the grinding pressure is achieved through linkage of the pressure adjusting assembly and the pressure sensor, the downward pressure can be adjusted in a stepless mode according to the medicine hardness, the limitation that traditional equipment depends on hardware replacement is broken through, and the full-scene requirements of soft medicine to hard medicine are efficiently met; by means of a vortex tube cooling system driven by a transmission assembly, low-temperature airflow is guided into a spiral groove of the grinding wheel to dissipate heat in real time, the grinding temperature is stabilized at the grinding temperature needed by corresponding medicine, and the problem that components are damaged due to friction heat production of traditional equipment is solved.

Description

Technical Field

[0001] The invention belongs to the technical field of pharmacology research auxiliary equipment, and in particular relates to a pharmacology laboratory auxiliary device in pharmacy. Background Art

[0002] In pharmacological research in pharmacology laboratories, drug grinding is the primary link that determines the reliability of the experiment. Its quality directly affects the accuracy of the results of pharmacodynamics, pharmacokinetics and toxicology studies. Auxiliary devices such as grinding are needed to conduct experiments during the research process.

[0003] The problems existing in the existing grinding device are mainly reflected in the following aspects: First, the grinding force is difficult to control. Most traditional grinding devices use a fixed mechanical structure, which makes it difficult to flexibly adjust the grinding pressure according to the characteristics of different drugs and experimental requirements. As a result, some hard drugs cannot be fully ground, while softer drugs may be damaged by excessive pressure, affecting the accuracy of experimental data. Secondly, the problem of heat generation during the grinding process is prominent. Under long-term, high-intensity grinding operations, traditional devices will generate a large amount of heat due to mechanical friction. Some temperature-sensitive drugs (enzyme drugs, mint, etc.) will degrade, volatilize or change their chemical structure due to heat, which will seriously interfere with the experimental results and even lead to erroneous research conclusions.

[0004] Third, the grinding efficiency and uniformity are poor. The grinding parts of traditional grinding devices have a single movement mode, and the drugs are unevenly distributed in the grinding chamber, which is prone to local over-grinding and local under-grinding. This leads to large differences in the particle size of the final grinding product, which cannot meet the strict requirements of high-precision pharmacology experiments for the uniformity of drug samples.

[0005] In view of the above problems, a pharmacological laboratory auxiliary device is proposed. Summary of the Invention

[0006] The technical problem to be solved by the present invention is to overcome the deficiencies of the prior art and provide a pharmacology laboratory auxiliary device for pharmaceuticals that can overcome the above problems or at least partially solve the above problems.

[0007] In order to solve the above technical problems, the basic concept of the technical solution adopted by the present invention is: A pharmacology laboratory auxiliary device for pharmacy comprises a base and a trough body fixedly mounted on the top of the base, and further comprises: a driving frame arranged on the base and a grinding wheel hinged on the driving frame, wherein the driving frame drives the grinding wheel to rotate inside the trough body; a pressure regulating assembly arranged on the base, wherein the output end of the pressure regulating assembly is rotationally connected to the driving frame, and the pressure regulating assembly applies downward pressure to the driving frame when the driving frame rotates; a cooling air source assembly connected to the driving frame through a transmission assembly, wherein the transmission assembly cooperates with the base to generate rotational power to drive the cooling air source assembly to generate low-temperature air and transmit it to the inside of the grinding wheel to absorb heat generated during grinding and discharge it.

[0008] As a preferred embodiment of the present invention: a box door is slidably installed at the bottom of the trough body, a pressure sensor is fixedly installed at the bottom of the box door, the pressure sensor is used to detect the downward pressure of the passing grinding wheel, and a discharge box arranged at the bottom of the box door is fixedly installed on the base.

[0009] As a preferred embodiment of the present invention: the driving frame includes a first transmission gear rotatably set on the top of the base and a reduction motor fixedly installed on the base, and the output end of the reduction motor is fixedly installed with a second transmission gear meshing with the first transmission gear; it also includes a first mounting frame slidably mounted on the first transmission gear, and the bottom of both ends of the first mounting frame are fixedly mounted with wheel frames, the grinding wheel is rotatably set on the wheel frame, and the center of the top of the first mounting frame is hinged to the output end of the pressure regulating assembly.

[0010] As a preferred embodiment of the present invention: the grinding wheel includes a mounting shaft rotatably mounted on a wheel frame, a metal wheel body rotatably mounted on the mounting shaft, a stone outer ring fixedly mounted on the outer ring of the metal wheel body, a stone side plate covering the metal wheel body fixedly mounted on the mounting shaft, a spiral cooling groove is provided on the outer wall of the metal wheel body, a vent is provided on the mounting shaft, and a cavity connecting the spiral cooling groove and the vent is provided between the stone side plate and the metal wheel body.

[0011] As a preferred embodiment of the present invention: the pressure regulating assembly includes a hydraulic cylinder fixedly mounted on the bottom of the base, a connecting rod fixedly mounted on the output end of the hydraulic cylinder, two sets of ball bearings arranged upper and lower are fixedly mounted on the connecting rod, a connecting sleeve is fixedly mounted on the first mounting frame, and the two sets of ball bearings are respectively in contact with the upper and lower ends of the connecting sleeve.

[0012] As a preferred embodiment of the present invention: the transmission assembly includes a gear ring fixedly mounted on the base and a third mounting frame fixedly mounted on the first mounting frame, a gear regulator is fixedly mounted on the bottom of the third mounting frame, a third transmission gear meshing with the gear ring is fixedly mounted on the input end of the gear regulator, and a crankshaft is fixedly mounted on the output end of the top of the gear regulator.

[0013] As a preferred embodiment of the present invention: the cooling air source assembly includes a pressure regulating box fixedly mounted on the top of the third mounting bracket, a two-way air pump and a vortex tube fixedly mounted on the side wall of the pressure regulating box, the driving end of the two-way air pump is connected to the crankshaft through a connecting rod, the exhaust end of the two-way air pump is connected to the input end of the pressure regulating box through an air pipe, an air guide pipe is fixedly mounted on the first mounting bracket, the air guide pipe is connected to the air vent through a rotating joint, and the output end of the pressure regulating box is connected to the air guide pipe through an exhaust pipe.

[0014] As a preferred embodiment of the present invention: a fourth mounting bracket is fixedly mounted on the third mounting bracket, a rotor generator and a battery are fixedly mounted on the top of the fourth mounting bracket, the rotor of the rotor generator is fixedly connected to the crankshaft, and the electric energy generated by the rotor generator is stored in the battery.

[0015] As a preferred embodiment of the present invention: a second mounting bracket is fixedly mounted on the side wall of the first mounting bracket, an electric telescopic rod is fixedly mounted on the top of the second mounting bracket, a sliding rod is slidably mounted on the second mounting bracket, a brush is fixedly mounted on the bottom of the sliding rod, and the output end of the electric telescopic rod is fixedly connected to the top of the sliding rod; a baffle is fixedly mounted on the bottom of the first mounting bracket, and a slot for the brush and the grinding wheel to pass through is provided on the top of the baffle.

[0016] An auxiliary grinding method comprises the following steps: Step 1: Raise the first mounting frame to open the baffle and separate the grinding wheel from the tank; Step 2: Place the medicinal materials to be ground into the tank; Step 3: Move the grinding wheel to above the herbs above the pressure sensor and drive the first mounting frame to descend until the pressure detected by the pressure sensor meets the grinding threshold; Step 4: driving the grinding wheel to rotate and grind the medicine, while transmitting low-temperature gas to the grinding wheel to absorb the heat generated during grinding; Step 5: adjusting the pressure during the milling process according to the pressure detected by the pressure sensor to ensure that the pressure during the milling process is stable; Step 6: Open the box door, drive the brush down, and cooperate with the rotating first mounting frame to discharge the ground medicine powder out of the tank.

[0017] After adopting the above technical solution, the present invention has the following beneficial effects compared with the prior art: the present invention realizes dynamic and precise control of the grinding pressure through the linkage between the pressure regulating component and the pressure sensor, and can steplessly adjust the downward pressure according to the hardness of the drug, breaking through the limitation of traditional equipment relying on hardware replacement, and efficiently adapting to the full range of drug needs from soft to hard drugs; with the help of the vortex tube cooling system driven by the transmission component, the low-temperature airflow is introduced into the spiral groove of the grinding wheel for real-time heat dissipation, so that the grinding temperature is stabilized at the grinding temperature required for the corresponding drug, solving the problem of component destruction caused by frictional heat generation in traditional equipment, while allowing higher speed and pressure to operate continuously, significantly improving the grinding efficiency; in addition, the device also has the advantages of self-sufficient transmission energy supply, waste heat recovery and utilization, automatic cleaning and discharge, and miniaturization, which comprehensively improves the accuracy, efficiency and convenience of laboratory grinding operations.

[0018] The specific embodiments of the present invention will be described in further detail below with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In the attached figure: Figure 1 Schematic diagram of the three-dimensional structure of a pharmacology laboratory auxiliary device proposed by the present invention Figure 1 ; Figure 2 Schematic diagram of the three-dimensional structure of a pharmacology laboratory auxiliary device proposed by the present invention Figure 2 ; Figure 3 Schematic diagram of the three-dimensional structure of a pharmacology laboratory auxiliary device proposed by the present invention Figure 3 ; Figure 4 This is a schematic structural diagram of a transmission assembly of a pharmacology laboratory auxiliary device proposed by the present invention; Figure 5 This is a schematic structural diagram of a pressure regulating assembly of a pharmacology laboratory auxiliary device proposed by the present invention; Figure 6 The invention proposes a pharmacological laboratory auxiliary device for pharmacy Figure 5 Schematic diagram of the structure at A in the middle; Figure 7 This is a schematic structural diagram of a grinding wheel of a pharmacology laboratory auxiliary device proposed by the present invention; Figure 8 This is a structural schematic diagram of a box door of a pharmacology laboratory auxiliary device proposed by the present invention.

[0020] In the figure: 1. Base; 11. Tank; 12. Box door; 13. Discharge box; 14. Pressure sensor; 2. Drive frame; 21. First transmission gear; 22. Reducer motor; 23. Second transmission gear; 24. Wheel frame; 25. First mounting frame; 3. Grinding wheel; 31. Mounting shaft; 32. Metal wheel body; 33. Stone outer ring; 34. Stone side plate; 35. Spiral cooling trough; 37. Ventilation hole; 38. Air guide tube; 4. Pressure regulating assembly; 41. Hydraulic cylinder; 42. Connecting rod; 43. Connecting sleeve; 44. Ball bearing; 5. Baffle; 51. Notch; 6. Second mounting bracket; 61. Slide rod; 62. Brush; 63. Electric telescopic rod; 7. Third mounting bracket; 71. Fourth mounting bracket; 8. Transmission assembly; 81. Gear ring; 82. Gear governor; 83. Third transmission gear; 84. Crankshaft; 9. Cooling air source assembly; 91. Two-way air pump; 92. Connecting rod; 93. Pressure regulating box; 94. Vortex tube; 95. Exhaust pipe; 10. Rotor generator; 101. Battery. DETAILED DESCRIPTION

[0021] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. The following embodiments are used to illustrate the present invention but are not used to limit the scope of the present invention.

[0022] Example: Refer to Figures 1-8 A pharmacology laboratory auxiliary device for pharmacy comprises a base 1 and a trough body 11 fixedly mounted on the top of the base 1, and further comprises: a driving frame 2 arranged on the base 1 and a grinding wheel 3 hinged on the driving frame 2, the driving frame 2 drives the grinding wheel 3 to rotate inside the trough body 11; a pressure regulating component 4 arranged on the base 1, the output end of the pressure regulating component 4 is rotatably connected to the driving frame 2, and the pressure regulating component 4 applies downward pressure to the driving frame 2 when the driving frame 2 rotates; a cooling air source component 9 connected to the driving frame 2 through a transmission component 8, the transmission component 8 cooperates with the base 1 to generate rotational power to drive the cooling air source component 9 to generate low-temperature air and transmit it to the inside of the grinding wheel 3 to absorb the heat generated during grinding and discharge it.

[0023] When in use, the medicine to be crushed (leaves, rhizomes, pearls, shells, dry bark, etc.) is first placed into the trough body 11, and then the driving frame 2 drives the grinding wheel 3 to rotate along the inner groove of the trough body 11. During this process, the pressure regulating component 4 and the driving frame 2 cooperate to drive the grinding wheel 3 downward. According to the grinding requirements, the downward pressure applied to the grinding wheel 3 can be adjusted by the pressure regulating component 4, and the medicine is ground in combination with the weight of the grinding wheel 3 until the medicine becomes powder.

[0024] During the grinding process, the low-temperature air generated by the cooling air source assembly 9 passes through the interior of the grinding wheel 3 to cool the grinding wheel 3 .

[0025] In summary, when the device is working, the grinding wheel 3 is cooled by low-temperature cooling air. On this basis, the device can allow the drive frame 2 to continue to operate at a higher speed or the pressure regulating component 4 to operate at a greater downward force while maintaining the stability of the drug components (to avoid high-temperature deterioration), thereby achieving a significant improvement in grinding efficiency. In short, low-temperature cooling air eliminates the negative impact of heat loss on the grinding process, providing the necessary conditions for high-speed, stable and efficient drug pulverization, and ultimately achieving the technical effect of accelerating the grinding speed.

[0026] In addition, the device can dynamically control the downward pressure of the grinding wheel 3 through the pressure regulating component 4. Compared with the limitation of traditional grinding equipment that relies on the weight of the grinding wheel 3 or the increase in size to increase the pressure, when the device processes drugs such as pearls and shells that require high-pressure grinding, the traditional solution requires replacing the grinding wheel 3 with a larger diameter and heavier weight to increase the contact pressure. The pressure regulating component 4 of the present device can directly apply a controllable downward pressure to the drive frame 2 through the hydraulic system. After the pressure is superimposed on the weight of the grinding wheel 3 itself, it can be equivalent to or even exceed the grinding force of the large-sized grinding wheel 3. Moreover, since the output pressure of the pressure regulating component 4 can be adjusted by the pressure regulating component 4, the pressure can be adjusted by the pressure regulating component 4. The control system (or manual) makes real-time and precise adjustments without the need to replace or modify the mechanical structure of the grinding wheel 3 (such as the diameter of the stone outer ring 33 and the weight of the metal wheel body 32), thereby avoiding the tedious process of disassembling and installing large components and significantly improving the adaptability of the device to drugs of different hardness. Therefore, this active pressure compensation mechanism enables the same set of grinding wheels 3 to meet the gentle grinding of soft drugs such as leaves and dry skin, and to achieve efficient crushing of hard drugs through the pressure multiplication effect of the pressure regulating component 4, fundamentally eliminating the technical defect of traditional equipment that relies on hardware replacement to match different grinding pressure requirements.

[0027] Since the pressure of the device can be adjusted as needed, the overall proportion of the device can be reduced, achieving miniaturization and space optimization, making it more suitable for scenarios such as laboratories that are sensitive to equipment size.

[0028] Reference Figure 8 A box door 12 is slidably installed at the bottom of the trough body 11 (the box door 12 can be fixed to the trough body 11 by magnetic attraction and threaded locking structure), and a pressure sensor 14 is fixedly installed at the bottom of the box door 12. The pressure sensor 14 is used to detect the downward pressure of the passing grinding wheel 3, and a discharge box 13 arranged at the bottom of the box door 12 is fixedly installed on the base 1.

[0029] After adding the medicine into the trough body 11, the grinding wheel 3 is rotated to the top of the box door 12, and then pressed down. The pressure is detected by the pressure sensor 14 to ensure the accuracy of the pressure applied to the medicine. After the medicine is ground into fragments, the gaps between the medicines are reduced, resulting in the original pressure being insufficient to grind the medicine into the required fineness during grinding. At this time, the pressure sensor 14 can be used to collect the downward force of the grinding wheel 3 in real time. When it is detected that the pressure is continuously lower than the set threshold (due to the refinement of the drug particles and the reduction of the gaps, the actual effective pressure decreases under the same downward pressure), the control system can drive the pressure regulating component 4 to dynamically increase the downward force (such as gradient pressurization according to a preset algorithm, or real-time adjustment according to the pressure difference) to compensate for the pressure loss caused by the reduction of the gap, thereby ensuring that the grinding force always meets the fineness requirements.

[0030] Reference Figure 2 、 Figure 3 、 Figure 5 and Figure 6 The driving frame 2 includes a first transmission gear 21 rotatably set on the top of the base 1 and a reduction motor 22 fixedly installed on the base 1, and the output end of the reduction motor 22 is fixedly installed with a second transmission gear 23 engaged with the first transmission gear 21; it also includes a first mounting frame 25 slidably mounted on the first transmission gear 21, and the bottom of both ends of the first mounting frame 25 are fixedly mounted with wheel frames 24, and the grinding wheel 3 is rotatably set on the wheel frame 24. The center of the top of the first mounting frame 25 is hinged to the output end of the pressure regulating assembly 4.

[0031] When in use, start the reduction motor 22, the reduction motor 22 drives the second transmission gear 23 to rotate, the second transmission gear 23 drives the first transmission gear 21 to rotate, the first transmission gear 21 drives the first mounting frame 25 to rotate, and the first mounting frame 25 drives the grinding wheel 3 to rotate around the inner groove of the trough body 11 to grind the medicinal materials in the trough body 11.

[0032] Reference Figure 1 and Figure 7 The grinding wheel 3 includes a mounting shaft 31 rotatably mounted on the wheel frame 24, a metal wheel body 32 rotatably mounted on the mounting shaft 31, a stone outer ring 33 fixedly mounted on the outer ring of the metal wheel body 32, a stone side plate 34 covering the metal wheel body 32 fixedly mounted on the mounting shaft 31, a spiral cooling groove 35 is provided on the outer wall of the metal wheel body 32, a vent 37 is provided on the mounting shaft 31, and a cavity connecting the spiral cooling groove 35 and the vent 37 is provided between the stone side plate 34 and the metal wheel body 32.

[0033] Before carrying out the drug grinding operation, the cooling air source component 9 needs to be connected and debugged with the mounting shaft 31 of the grinding wheel 3 to ensure that the cooling air source component 9 can stably output low-temperature gas, and that the vent hole 37 is tightly connected to the pipe interface of the cooling air source component 9 to prevent leakage of low-temperature gas and ensure the normal operation of the cooling system. At the same time, check whether the connection between the stone outer ring 33, the stone side plate 34 and the metal wheel body 32 is firm to avoid loose components affecting the operation during the grinding process.

[0034] When in use, the low-temperature gas discharged from the cooling air source assembly 9 enters the spiral cooling groove 35 through the vent 37, then absorbs the heat generated when the stone outer ring 33 and the stone side plate 34 grind the medicinal materials, and then is discharged through the vent 37 at the other end. After the grinding operation is completed, the cooling air source assembly 9 is closed and the connection with the mounting shaft 31 is disconnected.

[0035] Clean the medicinal materials remaining on the surface of the stone outer ring 33 and the stone side plate 34. If the stone parts are worn, they can be replaced according to the situation.

[0036] At the same time, check whether the surface of the metal wheel body 32 is damaged and whether the vent hole 37 is blocked to ensure that the grinding wheel 3 is in good performance when used next time.

[0037] In summary, the design of the grinding wheel 3 and its cooperation with the cooling air source component 9 can achieve cooling of the grinding wheel 3, thereby solving the problems of the traditional grinding wheel 3 causing damage to the medicinal ingredients and reduced grinding efficiency due to frictional heat generation, and is particularly suitable for temperature-sensitive herbal medicines, animal medicines, etc.; the composite structure of metal and stone, combined with efficient heat dissipation, significantly improves the service life and stability of the grinding wheel 3; the entire cooling process cooperates with the grinding operation to achieve high-precision and high-quality drug grinding, providing reliable sample preparation guarantees for pharmacological experiments.

[0038] Reference Figure 5 The pressure regulating assembly 4 includes a hydraulic cylinder 41 fixedly mounted on the bottom of the base 1, a connecting rod 42 fixedly mounted on the output end of the hydraulic cylinder 41, two sets of ball bearings 44 set up upper and lower are fixedly mounted on the connecting rod 42, and a connecting sleeve 43 is fixedly mounted on the first mounting frame 25, and the two sets of ball bearings 44 are respectively connected to the upper and lower ends of the connecting sleeve 43.

[0039] While the driving frame 2 drives the grinding wheel 3 to rotate, the driving frame 2 can be lowered by the hydraulic cylinder 41, thereby lowering the grinding wheel 3. By continuously applying downward pressure to the first mounting frame 25, the grinding pressure of the grinding wheel 3 on the medicinal materials can be adjusted. While applying pressure, the balls inside the two sets of ball bearings 44 can reduce the friction between the ball bearings 44 and the connecting sleeve 43 when the first mounting frame 25 rotates, which not only ensures that the first mounting frame 25 can rotate smoothly and maintain a stable grinding trajectory of the grinding wheel 3, but also avoids energy loss and component wear caused by excessive friction resistance, thereby extending the service life of the equipment. At the same time, the rolling of the balls also ensures the consistency and accuracy of the pressure regulation, so that the pressure applied by the hydraulic cylinder 41 can be stably and efficiently transmitted to the grinding wheel 3.

[0040] Reference Figure 4 and Figure 6 The transmission assembly 8 includes a gear ring 81 fixedly mounted on the base 1 and a third mounting frame 7 fixedly mounted on the first mounting frame 25. A gear regulator 82 is fixedly mounted on the bottom of the third mounting frame 7. The input end of the gear regulator 82 is fixedly mounted with a third transmission gear 83 meshing with the gear ring 81. The output end of the top of the gear regulator 82 is fixedly mounted with a crankshaft 84. The cooling air source assembly 9 includes a pressure regulating box 93 fixedly mounted on the top of the third mounting frame 7. A two-way air pump 91 and a vortex tube 94 are fixedly mounted on the side wall of the pressure regulating box 93. The driving end of the two-way air pump 91 is connected to the crankshaft 84 through a connecting rod 92, and the exhaust end of the two-way air pump 91 is connected to the input end of the pressure regulating box 93 through an air pipe. An air guide pipe 38 is fixedly mounted on the first mounting frame 25. The air guide pipe 38 is connected to the vent hole 37 through a rotating joint, and the output end of the pressure regulating box 93 is connected to the air guide pipe 38 through an exhaust pipe 95.

[0041] When the driving frame 2 rotates, the first mounting frame 25 drives the third mounting frame 7 to rotate. During this process, the third transmission gear 83 rotates in cooperation with the fixed gear ring 81. The third transmission gear 83 drives the gear governor 82 (for amplifying the output torque) to rotate. The gear governor 82 drives the crankshaft 84 to rotate. The crankshaft 84 drives the driving end of the two-way air pump 91 to move back and forth through the connecting rod 92, thereby sucking external air into the pressure regulating box 93. The pressure of the gas entering the vortex tube 94 is controlled by the pressure regulating valve on the pressure regulating box 93. The air entering the vortex tube 94 is heat exchanged to generate low-temperature air and high-temperature air. The low-temperature air is sent to the air guide pipe 38 through the exhaust pipe 95, and then discharged into the grinding wheel 3 through the vent 37 to cool the grinding wheel 3.

[0042] In order to prevent the vortex tube 94 from making excessive noise, the outer wall of the vortex tube 94 may be covered with sound insulation cotton.

[0043] In order to improve energy utilization, a hot drying box can also be installed on the first mounting frame 25, and then hot air is introduced into the hot drying box and cooperated with the air supply system in the hot drying box to produce hot air of corresponding temperature to dry the medicinal materials that need to be hot-dried.

[0044] In this embodiment, the air supply system rotates together with the driving frame 2 , thereby avoiding the occurrence of phenomena such as air pipe entanglement, and improving the low-temperature stability provided by the cooling air source component 9 for the grinding wheel 3 .

[0045] Reference Figure 4 A fourth mounting bracket 71 is fixedly mounted on the third mounting bracket 7, and a rotor generator 10 and a battery 101 are fixedly mounted on the top of the fourth mounting bracket 71. The rotor of the rotor generator 10 is fixedly connected to the crankshaft 84, and the electric energy generated by the rotor generator 10 is stored in the battery 101.

[0046] When in use, the crankshaft 84 drives the rotor of the rotor generator 10 to rotate, thereby causing the rotor generator 10 to generate electricity. The electric energy generated by the rotor generator 10 is stored in the battery 101, and then powers the various electric control components on the first mounting bracket 25, reducing the occurrence of wire entanglement and other minor problems, and improving the stability of the auxiliary device during operation.

[0047] Reference Figure 2 A second mounting frame 6 is fixedly mounted on the side wall of the first mounting frame 25, an electric telescopic rod 63 is fixedly mounted on the top of the second mounting frame 6, a slide rod 61 is slidably mounted on the second mounting frame 6, a brush 62 is fixedly mounted on the bottom of the slide rod 61, and the output end of the electric telescopic rod 63 is fixedly connected to the top of the slide rod 61; a baffle 5 is fixedly mounted on the bottom of the first mounting frame 25, and a slot 51 is provided on the top of the baffle 5 for the brush 62 and the grinding wheel 3 to pass through.

[0048] When in use, the baffle 5 rotates along with the first mounting frame 25 . The baffle 5 is mainly used to prevent the medicinal materials from being separated from the trough body 11 during the high-speed grinding process.

[0049] After the grinding is completed, the electric telescopic rod 63 drives the slide bar 61 to descend, and the slide bar 61 drives the brush 62 to descend. Then, during the rotation of the first mounting frame 25, the brush 62 can scrape the powder to the discharge port of the trough body 11 for discharge.

[0050] In summary, the device realizes real-time cooling of the grinding wheel 3 by cooperating with the cooling air source component 9 and the spiral cooling groove 35 and the air vent 37 of the grinding wheel 3. The low-temperature air absorbs the friction heat of grinding, thereby preventing the drugs (such as plant leaves and animal medicinal materials) from being deteriorated due to high temperature. It is particularly suitable for temperature-sensitive ingredients (such as volatile oils and enzymes), ensuring the stability of the components of pharmacological experimental samples. In addition, the low-temperature environment can inhibit the growth of microorganisms, reduce the risk of drug contamination during the grinding process, and improve the safety of experimental samples. The heat absorption of the low-temperature gas can eliminate the limitations of heat loss on the equipment, allowing the drive frame 2 to work continuously at a higher speed and the pressure regulating component 4 to work at a greater downward force, thereby increasing the speed and pressure of the grinding wheel 3, and increasing the grinding pressure and grinding speed. For example, when processing hard drugs such as pearls and shells, there is no need to reduce the speed due to heat dissipation problems, and the crushing amount per unit time is significantly increased.

[0051] The device can steplessly adjust the downward pressure of the grinding wheel 3 through the pressure regulating component 4 (hydraulic cylinder 41 + ball bearing 44). After superposition with the grinding wheel 3, the equivalent pressure covers the full range of scenarios for soft (leafs, dry skin) to hard (pearls, shells) drugs. In addition, the above design can enable the device to abandon the cumbersome method of traditional equipment that relies on replacing large-sized grinding wheels 3. Through the active pressure compensation mechanism, the same set of grinding wheels 3 can adapt to drugs of different hardness, reducing hardware replacement costs and time losses. The grinding pressure is monitored in real time through the pressure sensor 14 at the bottom of the trough body 11. When the gap is reduced due to the refinement of the drug particles and the actual pressure drops, the control system automatically drives the hydraulic cylinder 41 to increase the pressure to ensure that the grinding fineness always meets the standard (such as adaptive adjustment from coarse crushing to 200 mesh ultrafine powder).

[0052] The transmission assembly 8 in the device utilizes the rotational kinetic energy of the drive frame 2 to drive the two-way air pump 91 and the rotor generator 10 through the gear ring 81, the third transmission gear 83, and the gear speed regulator 82, thereby achieving self-sufficiency in cooling air source and power supply, thereby reducing dependence on external air sources and power lines, avoiding faults such as air pipe entanglement and wire dragging, and improving the stability of the device during operation.

[0053] During use, waste heat can also be recovered and expanded. The high-temperature air generated by the vortex tube 94 can be introduced into the hot drying box, and cooperated with the drying box's own air supply system to achieve pre-treatment and drying of medicinal materials, forming a multifunctional integration of grinding-cooling-drying, thereby improving space utilization (traditional drying equipment requires a separate heating system).

[0054] The device adjusts the efficient pressure output of the components so that the grinding wheel 3 does not need to rely on a large deadweight, thereby reducing the overall size of the device compared to traditional equipment, adapting to the narrow space of the laboratory (such as use in a fume hood), and making it more convenient to move and store.

[0055] Automatic cleaning and discharge The electric telescopic rod 63 drives the brush 62 to automatically clean the residual powder on the inner wall of the tank body 11. Cooperating with the bottom box door 12 and the discharge box 13, a one-button operation of grinding-collecting-cleaning is realized, which improves the convenience of taking out materials.

[0056] An auxiliary grinding method comprises the following steps: Step 1: Raise the first mounting frame 25 to open the baffle 5 and separate the grinding wheel 3 from the tank 11; Step 2: Lay the medicinal materials to be ground into the tank 11; Step 3: Move the grinding wheel 3 to the top of the herbs above the pressure sensor 14 and drive the first mounting frame 25 to descend until the pressure detected by the pressure sensor 14 meets the grinding threshold; Step 4: driving the grinding wheel 3 to rotate and grind the medicine, while transmitting low-temperature gas to the grinding wheel 3 to absorb the heat generated during grinding; Step 5: adjusting the pressure during the milling process according to the pressure detected by the pressure sensor 14 to ensure that the pressure during the milling process is stable; Step 6: Open the box door 12 and drive the brush 62 downward to cooperate with the rotating first mounting frame 25 to discharge the ground medicine powder out of the tank body 11.

[0057] The above description is merely a preferred embodiment of the present invention and does not constitute any form of limitation to the present invention. Although the present invention has been disclosed as above in terms of a preferred embodiment, it is not intended to limit the present invention. Any technician familiar with the present invention can make slight changes or modifications to equivalent embodiments using the above-mentioned technical contents without departing from the scope of the technical solution of the present invention. However, any simple modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the solution of the present invention.

Claims

1. A pharmacology laboratory auxiliary device for pharmacy, comprising a base (1) and a trough (11) fixedly mounted on the top of the base (1), characterized in that: Also includes: A driving frame (2) is provided on the base (1), and a grinding wheel (3) is hingedly connected to the driving frame (2), wherein the driving frame (2) drives the grinding wheel (3) to rotate inside the trough (11); a pressure regulating assembly (4) is provided on the base (1), wherein the output end of the pressure regulating assembly (4) is rotationally connected to the driving frame (2), and the pressure regulating assembly (4) applies downward pressure to the driving frame (2) when the driving frame (2) rotates; A cooling air source component (9) is connected to the drive frame (2) through a transmission component (8). The transmission component (8) cooperates with the base (1) to generate a rotating force to drive the cooling air source component (9) to generate low-temperature air, which is then transmitted to the interior of the grinding wheel (3) to absorb and discharge heat generated during grinding.

2. A pharmaceutical pharmacology laboratory auxiliary device according to claim 1, characterized in that: A box door (12) is slidably mounted on the bottom of the trough body (11), a pressure sensor (14) is fixedly mounted on the bottom of the box door (12), and the pressure sensor (14) is used to detect the downward pressure of the passing grinding wheel (3). A discharge box (13) arranged at the bottom of the box door (12) is fixedly mounted on the base (1).

3. A pharmaceutical pharmacology laboratory auxiliary device according to claim 1, characterized in that: The driving frame (2) comprises a first transmission gear (21) rotatably arranged on the top of the base (1) and a reduction motor (22) fixedly mounted on the base (1), wherein the output end of the reduction motor (22) is fixedly mounted with a second transmission gear (23) meshing with the first transmission gear (21); It also includes a first mounting frame (25) slidably mounted on the first transmission gear (21), with wheel frames (24) fixedly mounted at the bottoms of both ends of the first mounting frame (25), the grinding wheel (3) being rotatably mounted on the wheel frames (24), and the center of the top of the first mounting frame (25) being hinged to the output end of the pressure regulating assembly (4).

4. A pharmaceutical pharmacology laboratory auxiliary device according to claim 3, characterized in that: The grinding wheel (3) includes a mounting shaft (31) rotatably mounted on a wheel frame (24), a metal wheel body (32) rotatably mounted on the mounting shaft (31), a stone outer ring (33) fixedly mounted on the outer ring of the metal wheel body (32), a stone side plate (34) covering the metal wheel body (32) fixedly mounted on the mounting shaft (31), a spiral cooling groove (35) provided on the outer wall of the metal wheel body (32), a vent (37) provided on the mounting shaft (31), and a cavity communicating with the spiral cooling groove (35) and the vent (37) provided between the stone side plate (34) and the metal wheel body (32).

5. A pharmaceutical pharmacology laboratory auxiliary device according to claim 3, characterized in that: The pressure regulating assembly (4) comprises a hydraulic cylinder (41) fixedly mounted on the bottom of the base (1); a connecting rod (42) is fixedly mounted on the output end of the hydraulic cylinder (41); two sets of ball bearings (44) are fixedly mounted on the connecting rod (42) and arranged in an upper and lower manner; a connecting sleeve (43) is fixedly mounted on the first mounting frame (25); and the two sets of ball bearings (44) are respectively connected to the upper and lower ends of the connecting sleeve (43).

6. A pharmaceutical pharmacology laboratory auxiliary device according to claim 4, characterized in that: The transmission assembly (8) comprises a gear ring (81) fixedly mounted on a base (1) and a third mounting frame (7) fixedly mounted on a first mounting frame (25); a gear regulator (82) is fixedly mounted on the bottom of the third mounting frame (7); a third transmission gear (83) meshing with the gear ring (81) is fixedly mounted on the input end of the gear regulator (82); and a crankshaft (84) is fixedly mounted on the output end of the top of the gear regulator (82).

7. A pharmaceutical pharmacology laboratory auxiliary device according to claim 6, characterized in that: The cooling air source assembly (9) includes a pressure regulating box (93) fixedly mounted on the top of the third mounting frame (7), a two-way air pump (91) and a vortex tube (94) fixedly mounted on the side wall of the pressure regulating box (93), a driving end of the two-way air pump (91) is connected to the crankshaft (84) through a connecting rod (92), an exhaust end of the two-way air pump (91) is connected to the input end of the pressure regulating box (93) through an air pipe, an air guide pipe (38) is fixedly mounted on the first mounting frame (25), the air guide pipe (38) is connected to the vent (37) through a rotating joint, and the output end of the pressure regulating box (93) is connected to the air guide pipe (38) through an exhaust pipe (95).

8. A pharmaceutical pharmacology laboratory auxiliary device according to claim 6, characterized in that: A fourth mounting frame (71) is fixedly mounted on the third mounting frame (7), a rotor generator (10) and a battery (101) are fixedly mounted on the top of the fourth mounting frame (71), a rotor of the rotor generator (10) is fixedly connected to a crankshaft (84), and electrical energy generated by the rotor generator (10) is stored in the battery (101).

9. A pharmaceutical pharmacology laboratory auxiliary device according to claim 3, characterized in that: A second mounting frame (6) is fixedly mounted on the side wall of the first mounting frame (25), an electric telescopic rod (63) is fixedly mounted on the top of the second mounting frame (6), a slide rod (61) is slidably mounted on the second mounting frame (6), a brush (62) is fixedly mounted on the bottom of the slide rod (61), and an output end of the electric telescopic rod (63) is fixedly connected to the top of the slide rod (61); A baffle (5) is fixedly mounted on the bottom of the first mounting frame (25), and a slot (51) for a brush (62) and a grinding wheel (3) to pass through is provided on the top of the baffle (5).

10. An auxiliary milling method using the pharmaceutical pharmacology laboratory auxiliary device according to claim 9, characterized in that: The following steps are involved: Step 1: Raise the first mounting frame (25) to open the baffle (5) and separate the grinding wheel (3) from the tank (11); Step 2: placing the medicinal materials to be ground into the tank (11); Step 3: Move the grinding wheel (3) to the top of the herbs above the pressure sensor (14) and drive the first mounting frame (25) to descend until the pressure detected by the pressure sensor (14) meets the grinding threshold; Step 4: driving the grinding wheel (3) to rotate and grind the medicine, while transmitting low-temperature gas to the grinding wheel (3) to absorb the heat generated during grinding; Step 5: adjusting the pressure during the milling process according to the pressure detected by the pressure sensor (14) to ensure that the pressure during the milling process is stable; Step 6: Open the box door (12), drive the brush (62) downward, and cooperate with the rotating first mounting frame (25) to discharge the ground medicine powder out of the tank body (11).

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