Multi-mode percutaneous temperature control device and method for nursing in anesthesia recovery period
Through dynamic adjustment of flexible electronic patch array and central control center, the problems of low permeability and position adaptability of traditional percutaneous analgesic patches are solved, and intelligent drug release and position adaptive administration are achieved, improving patient comfort and nursing efficiency.
Patent Information
- Application Number
- CN202510800933.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-16
- Publication Date
- 2025-08-15
AI Technical Summary
Traditional percutaneous analgesic patches have low permeability and slow onset, so they cannot dynamically adjust the dosage area and dosage, and the patch has poor contact with the skin, so they cannot adapt to changes in the patient's position.
It adopts a flexible electronic patch array, integrates micro pressure sensors, temperature sensors, heating elements and drug reservoirs, dynamically adjusts the heating elements and drug release rate through the central control center, and combines electrocardiogram signals to adjust pain levels and position changes.
It has achieved intelligent release of drugs, improved permeability and dynamic adjustment capabilities, adapted to position changes, reduced the need for artificial examinations, and improved patient comfort and nursing efficiency.
Smart Images
Figure CN120478047A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of smart pain relief patches, and specifically to a multimodal transcutaneous temperature control device and method for anesthesia recovery period care. Background Art
[0002] A transdermal analgesic patch is a topical medication patch that delivers medication directly through the skin to relieve pain. The drug ingredients in the patch are slowly released through the skin, maintaining effective drug concentrations for extended periods of time and providing sustained analgesia. This eliminates the need for frequent oral or injection medications and improves patients' quality of life. Compared to oral medications, transdermal analgesic patches avoid irritation and damage to the gastrointestinal tract, making them suitable for patients with poor gastrointestinal function or those who cannot tolerate oral medications. However, traditional transdermal analgesic patches have low drug permeability, rely on passive diffusion, require large doses, and have a slow onset of action. They also have poor contact with the skin, leading to local detachment when the patient rolls over. Furthermore, traditional transdermal analgesic patches cannot dynamically adjust the drug delivery area and dosage, such as when the pain area shifts with a patient's position. Therefore, making transdermal analgesic patches more intelligent has become a key issue that needs to be addressed.
[0003] Therefore, how to overcome the above-mentioned technical problems and defects becomes a problem that needs to be solved in a key manner. Summary of the Invention
[0004] In order to overcome the above-mentioned problems existing in the prior art, the present application provides a multimodal transcutaneous temperature control device and method for anesthesia recovery period care, which adopts the following technical solutions:
[0005] In a first aspect, the present application provides a multimodal transcutaneous temperature control method for anesthesia recovery care, comprising:
[0006] A plurality of independent micro-patch units are provided based on a flexible electronic patch array, wherein each independent micro-patch unit is provided with a micro pressure sensor, a micro temperature sensor, a micro heating element and a drug reservoir;
[0007] The central control center obtains the pressure value of each independent micro-patch unit, judges the pressure value of each independent micro-patch unit, and sends an opening instruction to the micro-heating element in the numbered area whose pressure value meets the preset threshold. The micro-heating element in the corresponding numbered area receives the instruction and turns on. The micro-heating element heats the corresponding numbered area to a first preset temperature threshold to control the drug release rate of the drug reservoir;
[0008] Obtain the remaining amount of drugs in the drug reservoir, and when the remaining amount of drugs in the drug reservoir is lower than a preset threshold, send a replacement reminder to the relevant responsible personnel.
[0009] Furthermore, each independent micro patch unit is assigned unique numbering information, and the numbering information assigned to each independent micro patch unit is associated and bound with the micro pressure sensor, the micro temperature sensor, and the micro heating element.
[0010] Furthermore, several independent micro patch units are connected through flexible circuits.
[0011] Furthermore, the heating temperature range of the micro heating element is 40°C-42°C.
[0012] Furthermore, the micro temperature sensor obtains the temperature of the corresponding numbered area in real time. When the temperature exceeds the preset threshold, the flexible electronic patch array is powered off and an alarm message is sent to the relevant person in charge.
[0013] Furthermore, controlling the drug release rate of the drug reservoir also includes: obtaining an electrocardiogram signal of the target object, converting the electrocardiogram signal into a pain level of the target object, adjusting the temperature value output of the micro-heating element based on the pain level, and changing the drug release rate of the drug reservoir.
[0014] Furthermore, an electrocardiogram signal of the target subject is obtained, the electrocardiogram signal is converted into a pain level of the target subject, and the temperature value output of the micro-heating element is adjusted based on the pain level to change the drug release rate of the drug reservoir, including:
[0015] Obtaining the original ECG signal of the target object, removing high-frequency noise interference through a low-pass filter to obtain a first filtered signal; passing the first filtered signal through a notch filter to eliminate power frequency interference in a specific band, and obtaining a filtered pure ECG signal;
[0016] Extract pain-related feature parameters from pure ECG signals;
[0017] Based on the extracted characteristic parameters, the pain level is divided according to the pre-set standards;
[0018] Predetermine the transcutaneous temperature control values corresponding to different pain levels;
[0019] After determining the pain level, the central control center sends instructions to the micro-heating element based on the corresponding relationship, adjusts the input power of the micro-heating element, and increases or decreases the temperature.
[0020] In a second aspect, the present application further provides a multimodal transcutaneous temperature control device for anesthesia recovery care, comprising:
[0021] The flexible electronic patch array module is used to set up a number of independent micro patch units based on the flexible electronic patch array, wherein each independent micro patch unit is provided with a micro pressure sensor, a micro temperature sensor, a micro heating element and a drug reservoir.
[0022] The pressure value judgment module is used for the central control center to obtain the pressure value of each independent micro-patch unit, and judge the pressure value of each independent micro-patch unit, and send an open instruction to the micro-heating element in the numbered area whose pressure value meets the preset threshold. The micro-heating element in the corresponding numbered area receives the instruction and turns on. The micro-heating element heats the corresponding numbered area to a first preset temperature threshold to control the drug release rate of the drug reservoir.
[0023] The drug remaining quantity acquisition module is used to obtain the remaining quantity of drugs in the drug reservoir. When the remaining quantity of drugs in the drug reservoir is lower than a preset threshold, a replacement reminder is sent to the relevant responsible personnel.
[0024] In a third aspect, the present application provides an electronic device, comprising:
[0025] One or more processors; a memory; and one or more computer programs, wherein the one or more computer programs are stored in the memory, and the one or more computer programs include instructions that, when executed by the device, cause the device to perform the method as described in the first aspect.
[0026] In a fourth aspect, the present application provides a computer-readable storage medium, which stores a computer program. When the computer-readable storage medium is run on a computer, the computer executes the method described in the first aspect.
[0027] In a fifth aspect, the present application provides a computer program, which, when executed by a computer, is used to execute the method described in the first aspect.
[0028] In one possible design, the program in the fifth aspect may be stored in whole or in part on a storage medium packaged with the processor, or may be stored in whole or in part on a memory not packaged with the processor.
[0029] This application has the following beneficial effects:
[0030] 1. This application sets up several independent micro-patch units based on a flexible electronic patch array, wherein each independent micro-patch unit is provided with a micro-pressure sensor, a micro-temperature sensor, a micro-heating element and a drug reservoir. This application sets up a micro-pressure sensor, a micro-temperature sensor, a micro-heating element and a drug reservoir through a flexible electronic patch array, which can better fit the application position of the target object and ensure good contact with the skin.
[0031] 2. This application obtains the pressure value of each independent micro-patch unit through a central control center, and judges the pressure value of each independent micro-patch unit, and sends an open instruction to the micro-heating element in the numbered area whose pressure value meets the preset threshold. The micro-heating element in the corresponding numbered area receives the instruction and turns on. The micro-heating element heats the corresponding numbered area to a first preset temperature threshold to control the drug release rate of the drug reservoir. This application promotes the release rate of drugs in the drug reservoir through micro-heating elements, actively increases the diffusion rate of the drug, and can dynamically adjust the drug administration to different areas. That is, when the target subject's body position changes and the pain area shifts, the drug release rate of the drug reservoir can be dynamically activated in the shifted area, making the transdermal analgesic patch more intelligent.
[0032] 3. This application obtains the remaining amount of drugs in the drug reservoir. When the remaining amount of drugs in the drug reservoir falls below a preset threshold, a replacement prompt is sent to the relevant responsible personnel. The relevant responsible personnel can replace the target object in a timely manner based on the prompt information, eliminating the need to frequently check the application position of the target object and solve the replacement problem of the flexible electronic patch array through manual judgment. This avoids the problem of not being able to pay attention to or forget to replace the patch when there is a shift change or when the nurse is busy, saving nurses' inspection and record time. BRIEF DESCRIPTION OF THE DRAWINGS
[0033] Figure 1 is an exemplary system architecture diagram to which the embodiments of the present application can be applied;
[0034] Figure 2 This is a schematic diagram of the working principle of the flexible electronic patch array according to an embodiment of the present application;
[0035] Figure 3 This is a flow chart of a multimodal transcutaneous temperature control method for anesthesia recovery care according to an embodiment of the present application;
[0036] Figure 4 This is a flow chart of drug release rate adjustment according to an embodiment of the present application;
[0037] Figure 5 This is a system flow chart of an embodiment of the present application;
[0038] Figure 6 It is a schematic diagram of a computer device according to an embodiment of the present application. DETAILED DESCRIPTION
[0039] Unless otherwise defined, all technical and scientific terms used herein have the same meanings as commonly understood by those skilled in the art to which this application belongs. The terms used in the specification of the application are for the purpose of describing specific embodiments only and are not intended to limit this application. The terms "including" and "having" and any variations thereof in the specification and claims of this application and the above-mentioned drawings are intended to cover non-exclusive inclusions. The terms "first", "second", etc. in the specification and claims of this application or the above-mentioned drawings are used to distinguish different objects, not to describe a specific order.
[0040] References herein to "embodiments" mean that a particular feature, structure, or characteristic described in connection with the embodiments may be included in at least one embodiment of the present application. The appearance of this phrase in various places in the specification does not necessarily refer to the same embodiment, nor does it constitute an independent or alternative embodiment that is mutually exclusive of other embodiments. It is understood, both explicitly and implicitly, by those skilled in the art that the embodiments described herein may be combined with other embodiments.
[0041] In order to enable those skilled in the art to better understand the solution of the present application, the technical solution in the embodiments of the present application will be clearly and completely described below in conjunction with the accompanying drawings.
[0042] like Figure 1 As shown, system architecture 100 may include terminal devices 101, 102, 103, a network 104, and a server 105. Network 104 is a medium for providing communication links between terminal devices 101, 102, 103 and server 105. Network 104 may include various connection types, such as wired or wireless communication links or fiber optic cables.
[0043] The target object can use the terminal devices 101, 102, and 103 to interact with the server 105 via the network 104 to receive or send messages, etc. Various communication client applications can be installed on the terminal devices 101, 102, and 103, such as web browser applications, shopping applications, search applications, instant messaging tools, email clients, social platform software, etc.
[0044] Terminal devices 101, 102, and 103 can be various electronic devices with display screens and support web browsing, including but not limited to smartphones, tablet computers, e-book readers, MP3 players (Moving Picture Experts Group Audio Layer III, Moving Picture Experts Group Audio Layer 3), MP4 (Moving Picture Experts Group Audio Layer IV, Moving Picture Experts Group Audio Layer 4) players, laptop computers, desktop computers, etc.
[0045] The server 105 may be a server that provides various services, such as a background server that provides support for web pages displayed on the terminal devices 101 , 102 , and 103 .
[0046] It should be noted that the multimodal transcutaneous temperature control method for anesthesia recovery care provided in the embodiment of the present application is generally executed by a server / terminal device. Accordingly, the multimodal transcutaneous temperature control device for anesthesia recovery care is generally set in the server / terminal device.
[0047] It should be understood that Figure 1 The number of terminal devices, networks and servers in the embodiment is merely illustrative. Any number of terminal devices, networks and servers may be provided as required.
[0048] The recovery period, a crucial stage in postoperative recovery, is the process by which the patient gradually recovers from anesthesia to normal consciousness. Pain can occur during recovery from anesthesia. Using a multimodal transcutaneous temperature patch on the patient's skin can help alleviate muscle or joint pain, reduce medication side effects, and enhance recovery.
[0049] This application provides a multimodal transcutaneous temperature control device and method for anesthesia recovery care. The multimodality is reflected in the dynamic control of drug release rate zones from a flexible electronic patch array based on changes in the target subject's posture. The device also incorporates a micro-heating element to control drug release, and the micro-heating element is controlled based on the target subject's electrocardiogram (ECG) signal to achieve temperature control in the corresponding zone, thereby controlling the drug release rate in that zone.
[0050] The target subject in this application refers to the target subject during the anesthesia recovery period.
[0051] Reference Figure 2 , Figure 2An optional flowchart of a multimodal transcutaneous temperature control method for anesthesia recovery care provided in an embodiment of the present disclosure. The multimodal transcutaneous temperature control method for anesthesia recovery care can be executed by a terminal, by a server, or by a terminal and a server in cooperation. The multimodal transcutaneous temperature control method for anesthesia recovery care includes but is not limited to the following steps 301 to 303.
[0052] Step 301: A plurality of independent micro-patch units are provided based on a flexible electronic patch array, wherein each independent micro-patch unit is provided with a micro-pressure sensor, a micro-temperature sensor, a micro-heating element, and a drug reservoir.
[0053] In one possible implementation, several independent micro-patch units are connected via flexible circuits, and the flexible electronic patch array can be adhered to the curved surface of the skin, such as the back, joints, and other surfaces that require application.
[0054] In a possible implementation, each independent micro patch unit is assigned unique numbering information, and the numbering information assigned to each independent micro patch unit is associated and bound with the micro pressure sensor, the micro temperature sensor, and the micro heating element.
[0055] It should be noted that the micro pressure sensor is used to detect the pressure value of the independent micro patch unit in the corresponding numbered area, the micro temperature sensor is used to detect the temperature value of the independent micro patch unit in the corresponding numbered area, and the micro heating element heats and releases the drug reservoir in the corresponding numbered area by heating.
[0056] In one possible embodiment, the micro-heating element may be a graphene electric heating film, which, when heated to 40°C-42°C, can promote the fluidity of stratum corneum lipids and improve drug transdermal penetration.
[0057] In the embodiment of the present application, the flexible electronic patch array may be powered by a flexible battery, such as a zinc-manganese thin film battery, or wireless power supply, such as NFC near-field communication power supply.
[0058] In step 302, the central control center obtains the pressure value of each independent micro-patch unit, determines the pressure value of each independent micro-patch unit, and sends an open instruction to the micro-heating elements in the numbered areas whose pressure values meet the preset threshold. The micro-heating elements in the corresponding numbered areas receive the instruction and turn on. The micro-heating elements heat the corresponding numbered areas to a first preset temperature threshold to control the drug release rate of the drug reservoir.
[0059] It should be noted that the micro-heating element, drug reservoir and number signal are associated and bound. When the central control center determines that the pressure value of the area meets the preset threshold, it obtains the number of the area and sends an open command to the micro-heating element associated with the area number to achieve the drug release rate of the drug reservoir in the area.
[0060] It should be noted that the first preset temperature threshold in the embodiment of the present application is greater than 37°C and less than 40°C.
[0061] In the examples of the present application, it should be noted that the drug reservoir is loaded with lidocaine / fentanyl gel, and the release rate is controlled by the thermosensitive hydrogel. The present application heats the thermosensitive hydrogel by a micro-heating element to promote the release rate of the drug in the reservoir.
[0062] In a possible embodiment, the present application controls the drug reservoir by turning on the micro-heating elements in the numbered areas to facilitate the release of the drug in the drug reservoir.
[0063] In one possible implementation, a micro temperature sensor acquires the temperature of a corresponding numbered area in real time. When the temperature exceeds a preset threshold, the flexible electronic patch array is powered off and an alarm message is sent to the relevant person in charge.
[0064] In the embodiment of the present application, it should be noted that the preset temperature threshold is 43° C. When the temperature is overheated, that is, exceeds 43° C., the flexible electronic patch array is directly powered off.
[0065] In one possible implementation, a micro temperature sensor acquires the temperature of the corresponding numbered area in real time and uploads it to a central control center. The central control center determines whether the temperature exceeds a preset threshold. When the preset threshold is exceeded, the central control center sends a power-off instruction to the flexible electronic patch array. The flexible electronic patch array responds to the power-off operation, and the central control center sends an alarm message to the nurse workstation.
[0066] In one possible embodiment, controlling the drug release rate from the drug reservoir further includes: acquiring an electrocardiogram (ECG) signal of a target subject, converting the ECG signal into a pain level of the target subject, adjusting the temperature output of the micro-heating element based on the pain level, and changing the drug release rate from the drug reservoir.
[0067] In the embodiment of the present application, controlling the drug release rate of the drug reservoir further includes: obtaining an electrocardiogram signal of the target subject, converting the electrocardiogram signal into a pain level of the target subject, adjusting the temperature value output of the micro-heating element based on the pain level, and changing the drug release rate of the drug reservoir. Please refer to Figure 4 , specifically:
[0068] Step 41, obtain the original ECG signal of the target object, remove high-frequency noise interference through a low-pass filter, and obtain a first filtered signal; pass the first filtered signal through a notch filter to eliminate the power frequency interference in a specific band, and obtain a filtered pure ECG signal. The power frequency interference in a specific band here refers to the 50 / 60Hz power frequency interference. The 50 / 60Hz power frequency interference mainly comes from the power system. When the ECG patch collects the ECG signal, it is easily affected by the electromagnetic field generated by these surrounding electrical equipment, thereby introducing power frequency interference. The present application uses a notch filter to filter the 50 / 60Hz power frequency interference, which can accurately suppress the interference signal of this frequency and has little effect on the ECG signal components of other frequencies.
[0069] Step 42: Extracting characteristic parameters related to pain from the pure ECG signal, wherein the characteristic parameters include average heart rate, time domain index of heart rate variability, and frequency domain index of heart rate variability.
[0070] It should be noted that the core of the application for calculating the average heart rate is based on the RR interval (i.e., the time interval between two adjacent QRS wave groups) in the electrocardiogram signal, and the average value of the heart rate is obtained by mathematical statistical methods, which will not be elaborated here. By calculating the average heart rate, the overall frequency of the heartbeat can be understood. Among them, the time domain indicators of heart rate variability are obtained, such as the standard deviation of adjacent RR intervals and the root mean square of the difference between adjacent RR intervals. The time domain indicators of heart rate variability are analyzed by analyzing the time series data of adjacent heartbeat cycles (RR intervals) to reflect the regulatory function of the autonomic nervous system on the heart. The time domain indicators of heart rate variability are obtained and will not be elaborated here. Among them, the frequency domain indicators of heart rate variability reveal the activity and balance relationship between the sympathetic and parasympathetic nerves in the autonomic nervous system by analyzing the frequency distribution of the RR interval sequence, such as low frequency power (LF), high frequency power (HF), LF / HF ratio, etc. These parameters can reflect the stress response of the autonomic nervous system to pain.
[0071] Step 43 , based on the extracted characteristic parameters and referring to pre-set standards, the pain level is classified. For example, the pain level is divided into four levels: Level 0 is no pain, corresponding to a normal heart rate and heart rate variability index; Level 1 is mild pain, with a slight increase in heart rate and a slight change in heart rate variability index; Level 2 is moderate pain, with a significantly increased heart rate and significant fluctuations in heart rate variability index; Level 3 is severe pain, with a significantly increased heart rate and a severely disturbed heart rate variability index.
[0072] Step 44 predetermines transcutaneous temperature control values corresponding to different pain levels. For example, at level 0, the transcutaneous temperature is maintained at 37°C to maintain a baseline state; at level 1, the temperature is raised to 38°C to promote slow drug release; at level 2, the temperature is set to 39°C to accelerate drug release; and at level 3, the temperature is raised to 40°C to maximize drug release and enhance the analgesic effect.
[0073] In step 45, after determining the pain level, the central control center sends instructions to the micro-heating element based on the corresponding relationship, adjusting the input power of the micro-heating element to increase or decrease the temperature. The micro-temperature sensor monitors the transcutaneous temperature control value in real time and provides feedback to the central control center to ensure that the actual temperature is consistent with the set temperature, forming a closed-loop control, accurately adjusting the transcutaneous temperature control value, and promoting drug release on demand.
[0074] The present application changes the drug release rate of the drug reservoir based on the pain level of the target object, involves collecting data of the target object, analyzing the data of the target object, and then outputting a suitable temperature value for the target object. It is a processing of the physiological parameters of the target object and can be processed by a computer.
[0075] In this embodiment, the temperature output of the micro-heating element is adjusted based on the pain level. Here, the temperature output is 40°C-42°C. When the temperature output reaches 40°C, the pore size of the thermosensitive hydrogel expands, and the drug release rate increases by 2 times. At higher temperatures, the pore size of the thermosensitive hydrogel expands further, and the drug release rate is even higher. However, the temperature cannot exceed 43°C.
[0076] In the embodiments of this application, it should be noted that the target subject's ECG signal can be obtained by using an ECG patch, i.e., a three-lead electrode array on the chest, to capture the heart's electrical activity and obtain the target subject's ECG signal. This application uses an ECG patch, which collects the target subject's ECG signal through close contact between the electrodes and the skin. The ECG patch has a built-in high-precision sensor that continuously collects electrical activity data generated by the heartbeat at a sampling frequency of no less than 250Hz.
[0077] Step 303: Obtain the remaining amount of the drug in the drug reservoir. When the remaining amount of the drug in the drug reservoir is lower than a preset threshold, a replacement reminder is sent to the relevant responsible personnel.
[0078] In one possible embodiment, the remaining amount of the drug in the drug reservoir is obtained, specifically as follows:
[0079] Obtain the initial total amount of drug in the drug reservoir, collect real-time temperature data based on a micro temperature sensor; integrate the real-time temperature data, accumulate the integral value from the start to the current time, calculate the cumulative amount of released drug based on a preset calibrated release coefficient, and obtain the remaining amount of drug by obtaining the difference between the initial total amount of drug and the cumulative amount of released drug.
[0080] For example, assuming that the real-time temperature data is T(t), the integral calculation of the real-time temperature data can be expressed as Where t is the current time, assuming the preset calibration coefficient is k, the cumulative amount of drug released can be expressed as: Q s (t) = k·S(t), assuming the initial total amount of drug is Q 总 , then the remaining amount of the drug can be expressed as: Q 剩余 (t) = Q 总 -Q s The preset calibration coefficient is k, which can be used to obtain the release amount per unit time through in vitro diffusion experiments, that is, to obtain the release rate of the drug at different temperatures, fit the temperature-release rate curve, determine the relationship between the release coefficient k and temperature, and then obtain the release coefficient k.
[0081] In an embodiment of the present application, when a replacement reminder is sent to the relevant responsible personnel, the entire flexible electronic patch array can be replaced, or the independent micro patch unit with the corresponding number can be replaced.
[0082] In an embodiment of the present application, during the ward rounds, the nurse can view the working status of the target object's flexible electronic patch array and the remaining drug information through the terminal device after obtaining the basic information of the target object.
[0083] Those skilled in the art will appreciate that all or part of the processes in the above-described method embodiments can be implemented by instructing the relevant hardware through a computer program. The computer program can be stored in a computer-readable storage medium. When the program is executed, it can include the processes in the above-described method embodiments. The aforementioned storage medium can be a non-volatile storage medium such as a magnetic disk, an optical disk, a read-only memory (ROM), or a random access memory (RAM).
[0084] It should be understood that although the steps in the flowcharts of the accompanying drawings are shown in sequence as indicated by the arrows, these steps are not necessarily executed in the order indicated by the arrows. Unless otherwise specified herein, there is no strict order restriction on the execution of these steps, and they can be executed in other orders. Moreover, at least some of the steps in the flowcharts of the accompanying drawings may include multiple sub-steps or multiple stages, and these sub-steps or stages are not necessarily executed at the same time, but can be executed at different times, and their execution order is not necessarily sequential, but can be executed in turn or alternately with other steps or at least a portion of the sub-steps or stages of other steps.
[0085] Continued reference Figure 5 , as a response to the above Figure 2 The present application provides an embodiment of a multi-modal transcutaneous temperature control device for anesthesia recovery period care. Figure 2 Corresponding to the method embodiment shown, the system can be specifically applied to various electronic devices, including: a flexible electronic patch array module 501, a pressure value determination module 502, and a drug remaining amount acquisition module 503, wherein:
[0086] The flexible electronic patch array module 501 is used to set up a number of independent micro patch units based on the flexible electronic patch array, wherein each independent micro patch unit is provided with a micro pressure sensor, a micro temperature sensor, a micro heating element and a drug reservoir.
[0087] The pressure value judgment module 502 is used for the central control center to obtain the pressure value of each independent micro-patch unit, judge the pressure value of each independent micro-patch unit, and send an open instruction to the micro-heating element in the numbered area whose pressure value meets the preset threshold. The micro-heating element in the corresponding numbered area receives the instruction and turns on. The micro-heating element heats the corresponding numbered area to a first preset temperature threshold to control the drug release rate of the drug reservoir.
[0088] The drug remaining amount acquisition module 503 is used to obtain the remaining amount of drugs in the drug storage, and when the remaining amount of drugs in the drug storage is lower than a preset threshold, a replacement reminder is sent to the relevant responsible personnel.
[0089] The present application sets up a number of independent micro-patch units based on a flexible electronic patch array, wherein each independent micro-patch unit is provided with a micro pressure sensor, a micro temperature sensor, a micro heating element and a drug reservoir. The central control center obtains the pressure value of each independent micro-patch unit, and judges the pressure value of each independent micro-patch unit, sends an opening instruction to the micro heating element of the numbered area whose pressure value meets the preset threshold, and the micro heating element of the corresponding numbered area receives the instruction to turn on, and the micro heating element heats the corresponding numbered area to the first preset temperature threshold to control the drug release rate of the drug reservoir. The remaining amount of the drug in the drug reservoir is obtained, and when the remaining amount of the drug in the drug reservoir is lower than the preset threshold, a replacement prompt is sent to the relevant responsible personnel. The present application can realize zoned temperature control and body position adaptive drug delivery.
[0090] To solve the above technical problems, the present application also provides a computer device. Figure 6 , Figure 6 This is a basic structural block diagram of the computer device in this embodiment.
[0091] The computer device 6 includes a memory 6a, a processor 6b, and a network interface 6c that are interconnected through a system bus. It should be noted that the figure only shows a computer device 6 having components 6a-6c, but it should be understood that it is not required to implement all the components shown, and more or fewer components can be implemented instead. Among them, those skilled in the art will understand that the computer device here is a device that can automatically perform numerical calculations and / or information processing according to pre-set or stored instructions, and its hardware includes but is not limited to a microprocessor, an application-specific integrated circuit (ASIC), a field-programmable gate array (FPGA), a digital signal processor (DSP), an embedded device, etc.
[0092] The computer device may be a desktop computer, notebook computer, PDA, cloud server, etc. The computer device may interact with the target object through a keyboard, mouse, remote control, touchpad, or voice control device.
[0093] The memory 6a includes at least one type of readable storage medium, including flash memory, a hard disk, a multimedia card, a card-type memory (e.g., SD or DX memory), random access memory (RAM), static random access memory (SRAM), read-only memory (ROM), electrically erasable programmable read-only memory (EEPROM), programmable read-only memory (PROM), magnetic storage, a magnetic disk, an optical disk, etc. In some embodiments, the memory 6a can be an internal storage unit of the computer device 6, such as the hard disk or memory of the computer device 6. In other embodiments, the memory 6a can also be an external storage device of the computer device 6, such as a plug-in hard disk equipped on the computer device 6, a smart media card (SMC), a secure digital (SD) card, a flash card, etc. Of course, the memory 6a can also include both the internal storage unit of the computer device 6 and its external storage device. In this embodiment, the memory 6a is generally used to store the operating system and various application software installed on the computer device 6, such as the program code of the multimodal transcutaneous temperature control method for anesthesia recovery care. In addition, the memory 6a can also be used to temporarily store various types of data that have been output or are to be output.
[0094] In some embodiments, the processor 6b can be a central processing unit (CPU), a controller, a microcontroller, a microprocessor, or other data processing chip. The processor 6b is generally used to control the overall operation of the computer device 6. In this embodiment, the processor 6b is used to execute program code stored in the memory 6a or process data, such as executing the program code for the multimodal transcutaneous temperature control method for anesthesia recovery care.
[0095] The network interface 6c may include a wireless network interface or a wired network interface. The network interface 6c is generally used to establish a communication connection between the computer device 6 and other electronic devices.
[0096] The present application also provides another embodiment, namely, providing a non-volatile computer-readable storage medium, which stores a program of a multimodal transcutaneous temperature control method for anesthesia recovery care. The multimodal transcutaneous temperature control method for anesthesia recovery care can be executed by at least one processor to enable the at least one processor to perform the steps of the multimodal transcutaneous temperature control method for anesthesia recovery care as described above.
[0097] Through the description of the above implementation methods, those skilled in the art can clearly understand that the above-mentioned embodiment methods can be implemented by means of software plus the necessary general hardware platform, and of course can also be implemented by hardware, but in many cases the former is a better implementation method. Based on this understanding, the technical solution of the present application, or the part that contributes to the prior art, can be embodied in the form of a software product, which is stored in a storage medium (such as ROM / RAM, magnetic disk, optical disk), and includes a number of instructions for enabling a terminal device (which can be a mobile phone, computer, server, air conditioner, or network device, etc.) to execute the methods described in each embodiment of the present application.
[0098] Obviously, the embodiments described above are only some of the embodiments of the present application, rather than all of the embodiments. The preferred embodiments of the present application are given in the accompanying drawings, but they do not limit the patent scope of the present application. The present application can be implemented in many different forms. On the contrary, the purpose of providing these embodiments is to make the understanding of the disclosure of the present application more thorough and comprehensive. Although the present application has been described in detail with reference to the aforementioned embodiments, for those skilled in the art, it is still possible to modify the technical solutions described in the aforementioned specific embodiments, or to make equivalent replacements for some of the technical features therein. Any equivalent structure made using the contents of the present application specification and the accompanying drawings, directly or indirectly used in other related technical fields, is also within the scope of patent protection of the present application.
Claims
1. A multimodal transcutaneous temperature control method for anesthesia recovery period care, characterized in that: include: A plurality of independent micro-patch units are provided based on a flexible electronic patch array, wherein each independent micro-patch unit is provided with a micro pressure sensor, a micro temperature sensor, a micro heating element and a drug reservoir; The central control center obtains the pressure value of each independent micro-patch unit, judges the pressure value of each independent micro-patch unit, and sends an opening instruction to the micro-heating element in the numbered area whose pressure value meets the preset threshold. The micro-heating element in the corresponding numbered area receives the instruction and turns on. The micro-heating element heats the corresponding numbered area to a first preset temperature threshold to control the drug release rate of the drug reservoir; Obtain the remaining amount of drugs in the drug reservoir, and when the remaining amount of drugs in the drug reservoir is lower than a preset threshold, send a replacement reminder to the relevant responsible personnel.
2. The multimodal transcutaneous temperature control method for anesthesia recovery period nursing according to claim 1, characterized in that: Each independent micro patch unit is assigned unique number information, and the number information assigned to each independent micro patch unit is associated and bound with the micro pressure sensor, the micro temperature sensor, and the micro heating element.
3. The multimodal transcutaneous temperature control method for anesthesia recovery period nursing according to claim 1, characterized in that: Several independent micro-patch units are connected through flexible circuits.
4. The multimodal transcutaneous temperature control method for anesthesia recovery period nursing according to claim 1, characterized in that: The heating temperature range of the micro heating element is 40℃-42℃.
5. The multimodal transcutaneous temperature control method for anesthesia recovery period nursing according to claim 1, characterized in that: The micro temperature sensor obtains the temperature of the corresponding numbered area in real time. When the temperature exceeds the preset threshold, the flexible electronic patch array is powered off and an alarm message is sent to the relevant person in charge.
6. The multimodal transcutaneous temperature control method for anesthesia recovery period nursing according to claim 1, characterized in that: Controlling the drug release rate of the drug reservoir also includes: obtaining an electrocardiogram signal of the target object, converting the electrocardiogram signal into a pain level of the target object, adjusting the temperature value output of the micro-heating element based on the pain level, and changing the drug release rate of the drug reservoir.
7. The multimodal transcutaneous temperature control method for anesthesia recovery period nursing according to claim 6, characterized in that: Acquire the target subject's electrocardiogram signal, convert the electrocardiogram signal into the target subject's pain level, adjust the temperature value output of the micro-heating element based on the pain level, and change the drug release rate of the drug reservoir, including: Obtaining the original ECG signal of the target object, removing high-frequency noise interference through a low-pass filter to obtain a first filtered signal; passing the first filtered signal through a notch filter to eliminate power frequency interference in a specific band, and obtaining a filtered pure ECG signal; Extract pain-related feature parameters from pure ECG signals; Based on the extracted characteristic parameters, the pain level is divided according to the pre-set standards; Predetermine the transcutaneous temperature control values corresponding to different pain levels; After determining the pain level, the central control center sends instructions to the micro-heating element based on the corresponding relationship, adjusts the input power of the micro-heating element, and increases or decreases the temperature.
8. A multimodal transcutaneous temperature control device for anesthesia recovery period nursing, used to implement the multimodal transcutaneous temperature control method for anesthesia recovery period nursing according to claims 1-7, characterized in that: include: The flexible electronic patch array module is used to set up a number of independent micro patch units based on the flexible electronic patch array, wherein each independent micro patch unit is provided with a micro pressure sensor, a micro temperature sensor, a micro heating element and a drug reservoir. The pressure value judgment module is used for the central control center to obtain the pressure value of each independent micro-patch unit, and judge the pressure value of each independent micro-patch unit, and send an open instruction to the micro-heating element in the numbered area whose pressure value meets the preset threshold. The micro-heating element in the corresponding numbered area receives the instruction and turns on. The micro-heating element heats the corresponding numbered area to a first preset temperature threshold to control the drug release rate of the drug reservoir. The drug remaining quantity acquisition module is used to obtain the remaining quantity of drugs in the drug reservoir. When the remaining quantity of drugs in the drug reservoir is lower than a preset threshold, a replacement reminder is sent to the relevant responsible personnel.
9. An electronic device, characterized in that: include: one or more processors; a memory for storing one or more programs; When the one or more programs are executed by the one or more processors, the one or more processors implement the method according to any one of claims 1 to 7.
10. A computer-readable storage medium having computer instructions stored thereon, characterized in that: When the instruction is executed by a processor, the steps of the method according to any one of claims 1 to 7 are implemented.