Oral thick paste production process
Through steps such as soaking enzymatic lysis, ultrasonic extraction, centrifugal separation, reverse osmosis concentration and pasteurization, the problems of large energy consumption and component damage of traditional paste are solved, efficient extraction and cost reduction are achieved, and the types of paste raw materials and product diversity are broadened.
Patent Information
- Application Number
- CN202510747184.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-05
- Publication Date
- 2025-08-19
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Traditional paste production methods consume a lot of energy and may damage the active ingredients, and have limited extraction effects, resulting in waste of medicinal materials and poor quality of finished products.
The steps of immersion enzymatic lysis, ultrasonic extraction, centrifugal separation, reverse osmosis concentration and pasteurization are adopted, combined with high-pressure extraction and boiling paste processing to improve the extraction rate of effective ingredients and reduce energy consumption.
Efficiently extract effective ingredients of Chinese medicinal materials, save raw materials and energy consumption, reduce costs, improve product quality, broaden the scope of application of raw materials, and develop more paste products.
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of traditional Chinese medicine paste preparation and production, in particular to a paste production process. Background Art
[0002] Paste is a traditional Chinese medicine formulation. It is a semi-fluid tonic made from traditional Chinese medicinal materials. It has the functions of nourishing and maintaining health, conditioning the body, and improving sub-health. Through the combination of traditional Chinese herbs, it provides comprehensive conditioning tailored to individual constitutions. It is commonly used to replenish qi and blood, benefit the liver and kidneys, and strengthen the spleen and stomach. It is suitable for people with long-term sub-health or those recovering from chronic illness.
[0003] Traditional methods for making ointments require repeated, prolonged boiling of raw medicinal materials to extract their active ingredients. This not only consumes significant energy but also has a high risk of damaging the active ingredients. Furthermore, boiling alone is often associated with limited extraction efficiency. These drawbacks ultimately impact the effectiveness of the finished ointment and result in waste of raw medicinal materials. Summary of the Invention
[0004] The technical problem to be solved by the present invention is to provide a cream production process to overcome the defects and shortcomings of the existing similar technologies and processes as described in the background technology.
[0005] The technical solution adopted by the present invention to solve the technical problem is: a cream production process, comprising the following processing steps: a. Pretreatment: soak and clean the various medicinal materials prepared according to the formula, remove impurities, chop and control the drying process; b. Soaking and enzymolysis: Soak the pretreated medicinal raw materials with pure water, and add appropriate amounts of cellulase, hemicellulase and pectinase to carry out enzymatic hydrolysis reaction. The soaking and enzymolysis time is 1h to 3h to obtain the enzymatic hydrolyzate of the medicinal raw materials; c. High-pressure extraction: The medicinal raw materials are transferred together with the enzymatic hydrolysate to the high-pressure extraction equipment. After the pressure is increased, maintained, and released, a crude extract of the medicinal raw materials with a high extraction rate is obtained; d. Ultrasonic extraction: The raw medicinal material and the crude extract are ultrasonically treated at an ultrasonic power of 200W to 300W, an ultrasonic frequency of 20kHz to 40kHz, and a treatment time of 20min to 30min to obtain a crude extract of the raw medicinal material with a higher extraction rate; e. Centrifugation: The crude extract obtained in step d was centrifuged, and the supernatant was taken as the refined extract after precipitation; f. Concentration and purification: The refined extract obtained in step e is concentrated and purified by reverse osmosis concentration (RO membrane) to obtain a concentrated extract of the medicinal material raw material; g. Boil the cream: add an appropriate amount of purified water to the concentrated extract obtained in step f and boil it. When the purified water is evaporated, add refined honey and an appropriate amount of rock sugar while stirring. The amount of refined honey added is 1 / 5 by weight of the concentrated extract. Continue to boil until the honey becomes a viscous paste. After the fire is stopped, wait for the honey to cool naturally to below 60 ℃ to obtain the finished paste. h. Sterilization and filling: The finished paste is sterilized by pasteurization, and the sterilized finished paste is bottled and filled by automatic filling equipment.
[0006] The beneficial effects of the present invention are as follows: the paste production process of the present invention can very efficiently extract the effective ingredients in the Chinese medicinal material raw materials, and almost does not cause damage to the effective ingredients, thereby achieving the purpose of saving raw materials and energy consumption, reducing costs, and improving the quality of paste products, and achieving the purpose of broadening the range of raw material types, so that more types of Chinese medicinal material raw materials can be suitable for this production process, thereby developing more categories of paste products, thereby meeting people's needs while broadening the market and bringing greater economic benefits. DETAILED DESCRIPTION
[0007] The present invention will be further described below by way of examples. Example
[0008] A production process for a cream, comprising the following processing steps: a. Pretreatment: Immerse and clean the various medicinal materials prepared according to the formula, remove impurities, chop them, and control the drying process. Immersion cleaning can clean the plant materials more thoroughly and thoroughly, leaving no dead corners, and almost completely remove all residues on the plant surface and impurities mixed in the raw materials; b. Soaking and enzymolysis: Soak the pretreated medicinal raw materials in pure water, and add appropriate amounts of cellulase, hemicellulase, and pectinase to carry out enzymolysis reaction. The soaking and enzymolysis time is 1 hour to 3 hours to obtain an enzymatic hydrolyzate of the medicinal raw materials. Cellulase, hemicellulase, and pectinase can effectively break down plant cell walls, thereby helping to release the active ingredients in the cells and improving the clarity of the liquid. In addition, cellulase itself has the effects and functions of promoting digestion and absorption, promoting the balance of intestinal flora, improving digestive system function, regulating immune response, and reducing inflammatory response, which is beneficial to human health. c. High-pressure extraction: The medicinal raw materials are transferred together with the enzymatic hydrolysate to the high-pressure extraction equipment. After the pressure is increased, maintained, and released, a crude extract of the medicinal raw materials with a high extraction rate is obtained. During the pressure increase stage, the pressure is rapidly increased from normal pressure to several hundred MPa within a few minutes. An ultra-high pressure difference is formed inside and outside the solid tissue cells. The extraction solvent (water) quickly penetrates into the vascular bundles and glandular cells inside the plant under the ultra-high pressure. As the pressure rises rapidly, the cell volume is compressed. If the deformation limit is exceeded, the cell will rupture, and the substances inside the cell will come into contact with the solvent and dissolve. If the deformation limit of the cell is not exceeded, the extraction solvent enters the plant cell under the action of high pressure, and the active ingredients are dissolved in the extraction solvent. The pressure holding stage: The ultra-high pressure causes the volume of the system to change, which promotes the shift of chemical equilibrium. The penetration of the solvent and the dissolution of the solute quickly reach equilibrium. Therefore, the pressure holding stage is very short and can generally be completed within a few minutes. The pressure relief stage: The pressure relief is generally completed within two to three seconds. The pressure of the tissue cells is rapidly reduced from the ultra-high pressure of several hundred MPa to normal pressure. Under the action of reverse pressure, the volume of the fluid and drug matrix explodes and expands, exerting a strong impact on the cell wall, cell membrane, plasma membrane, nuclear membrane, vacuole, microtubules, etc., causing deformation. If the deformation exceeds its deformation limit, the cell structure will become loose, with holes, ruptures, and other structural changes. The active ingredient and the solvent will fully contact, and the solution containing the active ingredient will quickly diffuse out of the cell. If the deformation of the cell wall under the action of reverse pressure does not exceed its deformation limit (permeability increases under high pressure), the solvent that has dissolved the active ingredient inside the cell will quickly transfer to the outside of the cell under the high osmotic pressure difference, achieving the purpose of extraction. d. Ultrasonic extraction: Ultrasonic treatment is performed on the raw medicinal materials together with the crude extract. The ultrasonic power is 200W to 300W, the ultrasonic frequency is 20kHz to 40kHz, and the treatment time is 20min to 30min to obtain a crude extract of the raw medicinal materials with a higher extraction rate. The cavitation effect, mechanical effect, and thermal effect of ultrasound are used to accelerate the release, diffusion, and dissolution of effective substances in plant cells, thereby improving the extraction rate.
[0009] e. Centrifugation: The crude extract obtained in step e was centrifuged, and the supernatant was taken as the refined extract after precipitation; f. Concentration and Purification: The extract obtained in step f is concentrated and purified using reverse osmosis (RO) to obtain a concentrated extract of the medicinal material. Compared with traditional evaporation and concentration methods, reverse osmosis concentration minimizes damage to heat-sensitive components in the extract, preserving the active ingredients in the extract as much as possible. g. Boil the cream: add an appropriate amount of purified water to the concentrated extract obtained in step f and boil it. When the purified water is evaporated, add refined honey and an appropriate amount of rock sugar while stirring. The amount of refined honey added is 1 / 5 by weight of the concentrated extract. Continue to boil until the honey becomes a viscous paste. After the fire is stopped, wait for the honey to cool naturally to below 60 ℃ to obtain the finished paste. h. Sterilization and filling: The finished paste is sterilized by pasteurization, and the sterilized finished paste is bottled and filled by automatic filling equipment.
[0010] This paste production process can very efficiently extract the active ingredients from Chinese medicinal materials with almost no damage to the active ingredients, thus achieving the goals of saving raw materials and energy consumption, reducing costs and improving product quality.
[0011] The above embodiments are only used to illustrate the present invention, and are not intended to limit the protection of the present invention. Any non-substantial changes based on the essential solution of the present invention should fall within the scope of protection of the present invention.
Claims
1. A cream production process, characterized by: The processing steps include: a. Pretreatment: soak and clean the various medicinal materials prepared according to the formula, remove impurities, chop and control the drying process; b. Soaking and enzymolysis: Soak the pretreated medicinal raw materials with pure water, and add appropriate amounts of cellulase, hemicellulase and pectinase to carry out enzymatic hydrolysis reaction. The soaking and enzymolysis time is 1h to 3h to obtain the enzymatic hydrolyzate of the medicinal raw materials; c. High-pressure extraction: The medicinal raw materials are transferred together with the enzymatic hydrolysate to the high-pressure extraction equipment. After the pressure is increased, maintained, and released, a crude extract of the medicinal raw materials with a high extraction rate is obtained; d. Ultrasonic extraction: The raw medicinal material and the crude extract are ultrasonically treated at an ultrasonic power of 200W to 300W, an ultrasonic frequency of 20kHz to 40kHz, and a treatment time of 20min to 30min to obtain a crude extract of the raw medicinal material with a higher extraction rate; e. Centrifugation: The crude extract obtained in step d was centrifuged, and the supernatant was taken as the refined extract after precipitation; f. Concentration and purification: The refined extract obtained in step e was concentrated and purified by reverse osmosis concentration to obtain a concentrated extract of the medicinal material; g. Boil the cream: add an appropriate amount of purified water to the concentrated extract obtained in step f and boil it. When the purified water is evaporated, add refined honey and an appropriate amount of rock sugar while stirring. The amount of refined honey added is 1 / 5 by weight of the concentrated extract. Continue to boil until the honey becomes a viscous paste. After the fire is stopped, wait for the honey to cool naturally to below 60 ℃ to obtain the finished paste. h. Sterilization and filling: The finished paste is sterilized by pasteurization, and the sterilized finished paste is bottled and filled by automatic filling equipment.