Injection needle blowing-off equipment and injection test system

Abstract

An example injection needle blow-off apparatus disclosed in the abstract includes a loading surface having a first side configured to contact a syringe and having a second side opposite the first side; and an adjustable blow-off spout adjacent to the second side of the loading surface, the adjustable blow-off spout comprising: a gas inlet configured to be coupled to a gas supply; and a gas outlet configured to direct gas from the gas inlet toward a position of a needle of the syringe, the gas outlet being adjustable to purge the needle over a range of distances from the second side of the loading surface.

Description

Technical Field

[0001] The present disclosure relates generally to injection device testing and, more particularly, to an injection needle blow-off apparatus and an injection testing system. Background Art

[0002] The injection testing system may test one or more aspects of an injection device (including an autoinjector), such as cap removal force, plunger actuation force, injection depth, needle retraction, and / or delivered dose. Summary of the Invention

[0003] There is disclosed an injection needle blow-off apparatus and an injection testing system, substantially as shown and described in conjunction with at least one of the accompanying drawings, as more fully set forth in the claims. BRIEF DESCRIPTION OF THE DRAWINGS

[0004] These and other features, aspects, and advantages of the present disclosure will be better understood when the following detailed description is read with reference to the accompanying drawings, in which like reference numerals represent like parts throughout, and in which:

[0005] Figure 1 is an example injection testing system for performing testing on an injection device according to aspects of the present disclosure.

[0006] Figure 2 is a block diagram of an example injection testing system including an injection needle blow-off apparatus according to aspects of the present disclosure.

[0007] Figure 3 yes Figure 2 A perspective view of an example embodiment of elements of an injection testing system.

[0008] Figure 4 yes Figure 3 A perspective view of an example injection needle blow-off device comprising a positioning plate and a blow-off nozzle.

[0009] Figure 5 yes Figure 3 Front view of an example injection needle blow-off device.

[0010] Figure 6 yes Figure 3 Bottom view of an example syringe needle blow-off device.

[0011] Figure 7A and Figure 7B yes Figure 3 An example of a stereoscopic view of a syringe needle blow-off device from different viewing angles.

[0012] Figure 8 yes Figure 3Front cross-sectional view of an example syringe needle blow-off device.

[0013] Figure 9A Another example embodiment of the blow-off nozzles is shown, wherein the blow-off nozzles each have an adjustable distance from the tip of the needle in a direction parallel to the needle.

[0014] Figure 9B Another example embodiment of the blow-off nozzles is shown, wherein the blow-off nozzles each have an adjustable angle to adjust the angle of the gas outlet relative to the bottom surface of the positioning plate.

[0015] The accompanying drawings are not necessarily drawn to scale. Where appropriate, similar or identical reference numbers are used to designate similar or identical components. DETAILED DESCRIPTION

[0016] A needle test device for measuring a dose delivered by an injection needle, particularly an autoinjector, includes a flask or other container positioned to capture and measure fluid expelled from the needle. In order to accurately measure the expelled fluid, the needle test device may include a blow-off method or other method to disengage a final amount of expelled fluid that may tend to remain attached to the needle through fluid attachment. While injection devices can have a wide range of geometries and sizes, conventional needle test devices have a limited range of testable needle lengths, at least in part due to the structure of the blow-off device. Changing the needle length to be tested may involve a relatively lengthy process of changing the blow-off.

[0017] The disclosed example injection needle blow-off apparatus and injection testing system provide a wider range of needle lengths that can be tested using the same blow-off apparatus. In some disclosed examples, the testable needle exposed length is 2 mm or greater, including the last drop of fluid expelled from the injection needle. In some examples, the position and / or orientation of one or more blow-off nozzles are adjustable relative to the needle position. By adjusting the position and / or orientation of the blow-off nozzles, the location of the gas delivered by the blow-off nozzles can be adjusted based on the needle length and the resulting position of the last drop of fluid expelled.

[0018] The disclosed example injection needle blow-off device includes: a loading surface having a first side configured to contact a syringe and having a second side opposite the first side; and an adjustable blow-off nozzle adjacent to the second side of the loading surface, the adjustable blow-off nozzle including: a gas inlet configured to be coupled to a gas supply; and a gas outlet configured to direct gas from the gas inlet toward the position of the syringe's needle, the gas outlet being adjustable to purge the needle within a certain distance range from the second side of the loading surface.

[0019] In some example injection needle blow-off devices, the adjustable blow-off nozzle is configured to have an adjustable distance from the orifice along a plane of the second side of the loading surface. In some example injection needle blow-off devices, the gas outlet is configured to blow at an angle away from the second side of the loading surface, and the gas outlet is configured to purge the needle at the needle location based on a distance between the adjustable blow-off nozzle and the needle in a plane perpendicular to the needle.

[0020] In some example injection needle blow-off devices, the adjustable blow-off nozzle is configured to have an adjustable distance from the needle tip of the needle in a direction parallel to the needle. In some example injection needle blow-off devices, the loading surface includes a positioning plate having an orifice extending from a first side of the positioning plate to a second side of the positioning plate. In some example injection needle blow-off devices, the adjustable blow-off nozzle is positioned on the first side of the orifice and further includes a second adjustable blow-off nozzle positioned on the second side of the orifice. In some example injection needle blow-off devices, the second adjustable blow-off nozzle includes: a second gas inlet, the second gas inlet being configured to be coupled to the gas supply device; and a second gas outlet, the second gas outlet being configured to direct the gas toward the position of the needle, the second gas outlet being adjustable to purge the needle within the aforementioned distance range. In some example injection needle blow-off devices, at least one dimension of the orifice is smaller than a corresponding dimension of the body of the syringe.

[0021] In some example needle blow-off devices, the adjustable blow-off nozzle is configured to have an adjustable angle of the gas outlet. In some example needle blow-off devices, the adjustable blow-off nozzle includes a body that defines a passage between the gas inlet and the gas outlet, and the passage is configured to increase at least one of a flow rate of the gas or a pressure of the gas between the gas inlet and the gas outlet. Some example needle blow-off devices further include a control circuit system configured to automatically control a blow-off actuator to adjust the position of the blow-off nozzle.

[0022] Some disclosed syringe testing devices include: a gas supply; a needle blow-off device, the needle blow-off device including: a loading surface having a first side configured to contact a syringe and having a second side opposite the first side; an adjustable blow-off nozzle adjacent to the second side of the loading surface, the adjustable blow-off nozzle including: a gas inlet configured to couple to the gas supply; and a gas outlet configured to direct gas from the gas inlet toward a position of a needle of the syringe, the gas outlet being adjustable to purge the needle within a certain distance range from the second side of the loading surface; and a control circuit system configured to control the gas supply to output the gas to the adjustable blow-off nozzle.

[0023] Some example syringe testing devices further include a syringe positioner configured to position the syringe, wherein the control circuit system is configured to control the syringe positioner to position the syringe. In some example syringe testing devices, the syringe positioner is configured to move the body of the syringe into contact with the loading surface.

[0024] Some example syringe testing devices further include a syringe actuator configured to actuate the syringe to expel the contents of the syringe through the needle when the needle of the syringe is adjacent to the adjustable blow-off nozzle, wherein the control circuitry is configured to control the syringe actuator to actuate the syringe. In some example syringe testing devices, the syringe actuator is configured to actuate the syringe when the body of the syringe contacts the loading surface.

[0025] Some example syringe testing devices further include a collection container configured to collect the contents expelled from the syringe. In some example syringe testing devices, the loading surface includes a positioning plate having an orifice extending from a first side of the positioning plate to a second side of the positioning plate, and wherein the adjustable blow-off nozzle is configured to have an adjustable distance from the orifice along a plane of the second side of the positioning plate, the gas outlet is configured to purge at an angle away from the second side of the positioning plate, and the gas outlet is configured to purge the needle at the location based on a distance between the adjustable blow-off nozzles and a distance from the orifice in a direction parallel to the second side of the positioning plate.

[0026] In some example syringe testing devices, the adjustable blow-off nozzle is configured to have an adjustable distance from the needle tip in a direction parallel to the needle. Some example syringe testing devices further include a second adjustable blow-off nozzle configured to direct gas toward the needle. In some example syringe testing devices, the gas supply device includes a compressed gas source, a pneumatic pump, or a blower.

[0027] Figure 1 1 is an example injection testing system 100 for performing tests on an injection device, such as an autoinjector 102. The example injection testing system 100 can be configured, for example, to perform some or all tests to evaluate the requirements of the ISO 11608-5 standard. The example injection testing system 100 can be, for example, a general-purpose testing system configured for injection testing.

[0028] Figure 1 The example injection testing system 100 includes: a positioning device (e.g., for positioning the autoinjector 102 in one or more positions and / or orientations for automatic testing); an actuator (e.g., for actuating components of the autoinjector 102, for actuating the positioning device, for positioning and / or orienting the test device, etc.); and / or sensors for measuring various aspects of the autoinjector 102 during testing (e.g., a load cell for measuring actuation force, an auditory sensor for detecting audible events), a mass scale for measuring an expelled dose, a displacement sensor and / or a position sensor for triggering a test step and / or for measuring displacement of components of the autoinjector 102, etc. The example injection testing system 100 further includes one or more user interface devices, such as displays 104a, 104b and an input device 106.

[0029] Figure 2 is a block diagram of an example injection test system 200 including an injection needle blow-off device. The example injection test system 200 may be used to implement Figure 1 Some or all components of the injection testing system 100.

[0030] The example injection testing system 200 includes a syringe positioner 202, a syringe actuator 204, a syringe collector 206, and a control circuit system 208. The syringe positioner 202 positions and / or orients a syringe 210 (e.g., an automatic syringe) for performing one or more tests in the injection testing system 200. For example, the syringe positioner 202 can grasp the syringe 210 and move and / or rotate the syringe 210 to perform the test. The position of the syringe positioner 202 and / or the syringe 210 can be measured by one or more displacement sensors 212, which provide displacement and / or position information to the control circuit system 208.

[0031] The syringe actuator 204 actuates one or more aspects of the syringe 210, such as the plunger or other injection mechanism of the syringe 210. The force applied by the syringe actuator 204 can be measured by a force sensor 214, which provides the force measurements to the control circuitry 208.

[0032] The syringe collector 206 includes a loading surface (e.g., a positioning plate 216), a blow-off nozzle 218, and a collection container 220. The collection container 220 and the syringe 210 are positioned so that when the syringe 210 is actuated to discharge the fluid contained in the syringe 210, the fluid is discharged into the collection container 220. The collection sensor 222 measures the mass and / or volume collected in the collection container 220 and provides the mass or volume measurement to the control circuit system 208.

[0033] The positioning plate 216 allows the needle 224 of the syringe 210 to extend through the positioning plate 216 toward the collection container 220. The positioning plate 216 can block the body 225 of the syringe 210 from extending through the positioning plate 216 using an orifice having an appropriate size for the needle 224 and body 225 of the syringe 210. To test the dispensing of the contained fluid, the syringe positioner 202 can position the syringe 210 in contact with or against the positioning plate 216 so that the needle 224 extends through the orifice of the positioning plate 216. When the syringe 210 is positioned, the syringe 210 can be actuated (e.g., manually or automatically via the syringe actuator 204) to expel the contents of the syringe 210 into the collection container 220.

[0034] While the examples disclosed herein use the positioning plate 216 as a loading surface, other examples may use different types of loading surfaces against which the syringe 210 can be actuated to expose the needle 224 and / or expel the contents of the syringe 210. For example, a rod or other structural member may be used that is positioned to contact the body of the syringe 210 on the top side of the loading surface and avoid obstructing the needle 224. In some such examples, the blow-off nozzle 218 may be coupled to another surface of the syringe collector 206 or otherwise adjustably supported within the syringe collector, adjacent to the bottom side of the loading surface and / or adjacent to the location of the needle 224.

[0035] When the actuation of the syringe 210 is completed, the blow-off nozzle 218 is controlled to blow the last drop of fluid from the needle tip or near the needle tip into the collection container 220. A gas supply 226 provides gas, such as nitrogen or air, to the blow-off nozzle 218. The gas supply 226 can be, for example, a compressed gas source, a pneumatic pump, or a blower. As disclosed in more detail below, the blow-off nozzle 218 can be positioned and / or oriented to adjust the position of the blow-off gas impacting the needle 224.

[0036] The example control circuitry 208 can be a general-purpose computer, a laptop computer, a tablet computer, and / or any other type of processing system configured to communicate with the sensors and actuators of the injection test system 200. For example, the control circuitry 208 includes a processor 228, a memory 230, and a storage device 232. The example processor 228 can be any general-purpose central processing unit (CPU) from any manufacturer. In some other examples, the processor 228 can include one or more specialized processing units, such as a RISC processor with an ARM core, a graphics processing unit, a digital signal processor, and / or a system on a chip (SoC). The processor 228 executes machine-readable instructions 234, which can be stored locally at the processor (e.g., in an included cache or SoC), stored in memory (e.g., random access memory or other volatile memory, read-only memory, or other non-volatile memory such as flash memory), and / or stored in the storage device 232. The example storage device 232 can be a hard drive, a solid-state storage drive, a hybrid drive, a RAID array, and / or any other mass data storage device.

[0037] Figure 3 yes Figure 2 The syringe collector 206 includes a housing 302, a positioning plate 216, a blow-off nozzle 218, and a mass scale 304 (eg, Figure 2 The collection sensor 222) is located within the housing. Figure 4 yes Figure 3 FIG. 2 is a perspective view of an example needle blow-off device including a positioning plate 216 and a blow-off nozzle 218 . Figure 5 yes Figure 2 Front view of an example injection needle blow-off device.

[0038] The positioning plate 216 is positioned below the top portion of the housing 302 so that the top surface of the positioning plate 216 is accessible to the syringe 210 through the housing 302. The positioning plate 216 is coupled to the housing 302 and can be replaced with other positioning plates to test different types of syringes (e.g., syringes with different needle lengths, different body sizes). Although the blow-off nozzle 218 is adjustable as disclosed in more detail below, replacing the positioning plate 216 and the attached blow-off nozzle 218 can allow for more rapid changes to accommodate different testing procedures for different syringes.

[0039] The blow-off nozzle 218 is coupled to the bottom surface 308 of the positioning plate 216 on opposite sides of the aperture 306 in the positioning plate 216. The needle 224 of the syringe 210 extends through the aperture 306 and protrudes from the bottom side of the positioning plate 216. When the syringe 210 is actuated, fluid is discharged from the needle 224 into a collection container 220 (e.g., on a mass scale 304 positioned below the needle 224).

[0040] like Figure 5 As shown, at the end of fluid discharge, a final amount of fluid tends to adhere to the needle 224 in the form of droplets 502. After actuation is complete, the control circuitry 208 controls the gas supply 226 and / or the blow-off nozzle 218 (e.g., via a valve or other control device) to purge gas 504 toward the needle 224, thereby expelling the droplets 502 into the collection container 220.

[0041] Figure 6 yes Figure 2 Bottom view of an example syringe needle blow-off device. Figure 7A and Figure 7B yes Figure 3 Different perspective views of an example needle blow-off device including a positioning plate 216 and a blow-off nozzle 218 are shown.

[0042] The example blow-off nozzles 218 each include a gas inlet 702 that is coupled to the gas supply 226 via a hose or other connection. Figure 7A and Figure 7B As shown, the blow-off nozzle 218 also includes a gas outlet 704 that directs gas received via a corresponding gas inlet 702 toward the location of the needle 224 .

[0043] Figure 7A and Figure 7B The example gas outlet 704 directs gas at least partially away from the bottom surface of the positioning plate 316. The blow-off nozzle 218 is also adjustable so that the gas outlet 704 can be adjusted to direct the gas 504 toward the tip of the needle 224 for a range of needle lengths. Figures 4 to 7B In the example of FIG, the blow-off nozzles 218 have an adjustable distance (e.g., in a direction toward and away from the orifice 306 of the positioning plate 216) along the plane of the bottom surface 308 of the positioning plate 216 (e.g., parallel to the bottom surface of the positioning plate 216 and in a plane perpendicular to the needle 224). To this end, each blow-off nozzle 218 includes a slot 602, a screw 604, and a pin 606 to allow adjustment of the position of the blow-off nozzle 218 and to secure the blow-off nozzle 218 in a desired position.

[0044] The screw 604 extends through the slot 602 and into the threaded hole in the positioning plate 216. The slot 602 extends in the adjustment direction of the blow-off nozzle 218 so that when the screw 604 is loosened from the positioning plate 216, the blow-off nozzle 218 can slide toward and away from the orifice 306. When the blow-off nozzle 218 is positioned in the desired position, the screw 604 can be tightened to clamp the blow-off nozzle 218 to the positioning plate 216. The example screw 604 can be replaced with a pin extending from the positioning plate 216 into the slot 602 and a different clamping mechanism (such as a clamp or clip coupled to the positioning plate 216) to clamp or otherwise secure the blow-off nozzle 218 in the desired position.

[0045] The pin 606 extends from the blow-off nozzle 218 into a corresponding slot in the positioning plate 216. The slot in the positioning plate 216 extends parallel to the slot 602 in the blow-off nozzle 218 and limits the rotation of the blow-off nozzle 218 (e.g., to keep the gas outlet 704 oriented toward the needle 224). The pin 606 can be replaced with another rotation limiting device (such as a bracket) that is coupled to the positioning plate 216 adjacent to the blow-off nozzle 218 to limit the rotation of the blow-off nozzle 218 and / or guide the movement of the blow-off nozzle. In some examples, the blow-off nozzle 218 can be coupled to one or more corresponding worm gears, rack and pinion gears, and / or other gear transmission systems that can be actuated to adjust the positioning of the blow-off nozzle 218.

[0046] Figure 8 yes Figures 4 to 7B A front cross-sectional view of an example blow-off nozzle 218. Figure 8 As shown, the example blow-off nozzle 218 includes a passage 802 extending from the gas inlet 702 toward the gas outlet 704. The cross-sectional area of the passage 802 decreases from the gas inlet 702 to the gas outlet 704 to increase the velocity of the gas 504.

[0047] like Figure 8 As shown, as the gas 504 exits the gas outlet 704, the passage 802 directs the gas 504 at least partially away from the bottom surface 308 of the positioning plate 216. As the blow-off nozzle 218 and the gas outlet 704 are adjusted (e.g., via the screw 604 and the slot 602) closer to the needle 224, the distance between the bottom surface 308 and the location on the needle 224 decreases due to the angle of the passage 802 at the gas outlet 704. Conversely, as the blow-off nozzle 218 and the gas outlet 704 are adjusted further away from the needle 224, the distance between the bottom surface 308 and the location on the needle 224 increases.

[0048] The example blow-off nozzle 218 may be constructed using additive manufacturing or 3D printing and / or using conventional subtractive manufacturing techniques to form the passageway 802 .

[0049] Figure 9A Another example embodiment of the blow-off nozzles 218 is shown, wherein the blow-off nozzles 218 each have an adjustable distance from the tip of the needle 224 in a direction parallel to the needle 224 (e.g., an adjustable distance from the bottom surface 308 of the positioning plate 216). Figure 9A In the example of FIG. 2 , the blow-off nozzle 218 includes a gas inlet 702 and a gas outlet 704. Instead of or in addition to being adjustable in a direction parallel to the bottom surface 308 of the positioning plate 216, Figure 9A The blow-off nozzle 218 can be adjusted along a pin 902 that is parallel to the exemplary needle 224. When the blow-off nozzle 218 is adjusted to the desired position, a set screw 904 can secure the blow-off nozzle 218 to the desired distance from the bottom surface 308. By adjusting the position of the blow-off nozzle 218, the position at which the gas 504 collides with the needle 224 can be adjusted.

[0050] In some other examples, a screw or other support structure may be used instead of a pin to support the blow-off nozzle 218. The set screw 904 may also be replaced with a pin, clamp, or other fixing device.

[0051] Figure 9B Another example embodiment of the blow-off nozzles 218 is shown, wherein the blow-off nozzles 218 each have an adjustable angle to adjust the angle of the gas outlet 704 relative to the bottom surface of the positioning plate 216. Figure 9B In the example shown, the blow-off nozzle 218 includes a gas inlet 702 and a gas outlet 704 .

[0052] Figure 9B The blow-off nozzle 218 is coupled to the positioning plate 216 via a ball joint 906 or other rotating joint (e.g., a hinge). In some examples, the ball joint 906 can be controlled by a gear transmission or other means to set the blow-off nozzle 218 at a desired angle. The angle of the gas outlet 704 and the gas 504, and therefore the position on the needle 224 where the gas 504 collides with the needle 224, can be adjusted by adjusting the angle of the blow-off nozzle 218.

[0053] like Figure 5 and Figure 8 As shown, the thickness T of the positioning plate 216 is reduced in a region 506 around the orifice 306 compared to the rest of the positioning plate 216. By reducing the thickness of the region 506 and / or adjusting the position of the blow-off nozzle 218 relative to the orifice 306, the range of needle lengths that can be tested is increased. For example, the example positioning plate 216 and blow-off nozzle 218 can be used to perform testing on needle lengths as low as 2 mm (measuring the exposed length of the needle 224).

[0054] The example blow-off nozzle 218 disclosed herein can be adjusted manually or automatically. For example, the blow-off nozzle 218 can be coupled to a motor, a gear transmission system and / or other actuators to control the positioning and / or orientation of the blow-off nozzle 218. In some examples, the injection test system 200 may include a needle detection sensor, such as an image sensor 236, which determines the length of the needle 224 and / or the positioning of the needle tip of the needle 224. For example, the image sensor 236 can determine the position of the needle tip of the needle 224 by analyzing the image of the positioned needle 224. Based on the determined needle tip, the control circuit system 208 uses the blow-off actuator 238 coupled to the blow-off nozzle 218 to automatically control the position and / or orientation of the blow-off nozzle 218 to guide the gas 504 toward the position of the needle tip of the needle 224.

[0055] While the disclosed examples include two blow-off nozzles on opposite sides of the needle, other examples may include a single blow-off nozzle or three or more blow-off nozzles.

[0056] The present method and system can be implemented with hardware, software, and / or a combination of hardware and software. The present method and / or system can be implemented in a centralized manner in at least one computing system, or can be implemented in a distributed manner in several interconnected computing systems with different elements. Any type of computing system or other device adapted to perform the method described herein is suitable. A typical combination of hardware and software can include a general-purpose computing system with a program or other code, which controls the computing system when loaded and executed so that the computing system performs the method described herein. Another typical embodiment can include a dedicated integrated circuit or chip. Some embodiments can include non-transient machine-readable (e.g., computer-readable) media (e.g., flash drive, optical disc, magnetic storage disk, etc.), which stores one or more lines of code that can be executed by a machine, so that the machine performs a process as described herein. As used herein, the term "non-transient machine-readable medium" is defined as including all types of machine-readable storage media and excluding propagation signals.

[0057] As used herein, the terms "circuit" and "circuitry" refer to physical electronic components (i.e., hardware) and any software and / or firmware ("code") that can configure the hardware, be executed by the hardware, and / or otherwise be associated with the hardware. As used herein, for example, a specific processor and memory can constitute a first "circuit" when executing the first one or more lines of code, and can constitute a second "circuit" when executing the second one or more lines of code. As used herein, "and / or" refers to any one or more of the multiple items connected by "and / or" in a list. As an example, "x and / or y" refers to any element in the three-element set {(x), (y), (x, y)}. In other words, "x and / or y" refers to "one or both of x and y." As another example, "x, y and / or z" refers to any element in the seven-element set {(x), (y), (z), (x, y), (x, z), (y, z), (x, y, z)}. In other words, "x, y and / or z" refers to "one or more of x, y and z." As used herein, the term "exemplary" means serving as a non-limiting example, instance, or illustration. As used herein, the terms "e.g.," and "for example" introduce a list of one or more non-limiting examples, instances, or illustrations. As used herein, a circuit system is "operable" to perform a function when it includes the necessary hardware and code (if necessary) to perform the function, regardless of whether performance of the function is disabled or not enabled (e.g., by a user-configurable setting, a factory adjustment, etc.).

[0058] Although the present method and / or system has been described with reference to certain embodiments, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted without departing from the scope of the present method and / or system. For example, the frames and / or components of the disclosed examples may be combined, divided, rearranged and / or otherwise modified. Additionally, many modifications may be made to adapt specific circumstances or materials to the teachings of the present disclosure without departing from the scope of the present disclosure. Therefore, the present method and / or system is not limited to the specific embodiments disclosed. Rather, the present method and / or system will include all embodiments that fall within the scope of the appended claims, both literally and according to the doctrine of equivalents.

Claims

1. A syringe needle blow-off device, comprising: a loading surface having a first side configured to contact a syringe and having a second side opposite the first side; as well as an adjustable blow-off nozzle, the adjustable blow-off nozzle being adjacent to the second side of the loading surface, the adjustable blow-off nozzle comprising: a gas inlet configured to be coupled to a gas supply; as well as A gas outlet is configured to direct gas from the gas inlet toward a location of a needle of the syringe, the gas outlet being adjustable to purge the needle within a range of distances from a second side of the loading surface.

2. The injection needle blowing-off device according to claim 1, wherein: The adjustable blow-off nozzle is configured to have an adjustable distance from an orifice along a plane of the second side of the loading surface.

3. The injection needle blowing-off device according to claim 2, wherein: The gas outlet is configured to purge at an angle away from the second side of the loading surface and is configured to purge the needle at the position of the needle based on a distance between the adjustable blow-off nozzle and the needle in a plane perpendicular to the needle.

4. The injection needle blowing-off device according to claim 1, wherein: The adjustable blow-off nozzle is configured to have an adjustable distance from the tip of the needle in a direction parallel to the needle.

5. The injection needle blowing-off device according to claim 1, wherein: The loading surface includes a positioning plate having an aperture extending from a first side of the positioning plate to a second side of the positioning plate.

6. The injection needle blow-off device according to claim 5, wherein: The adjustable blow-off nozzle is positioned on a first side of the orifice, and further includes a second adjustable blow-off nozzle positioned on a second side of the orifice.

7. The injection needle blow-off device according to claim 6, wherein: The second adjustable blow-off nozzle comprises: a second gas inlet configured to be coupled to the gas supply; and A second gas outlet is configured to direct the gas toward the location of the needle, the second gas outlet being adjustable to purge the needle within the distance range.

8. The injection needle blow-off device according to claim 5, wherein: At least one dimension of the orifice is smaller than a corresponding dimension of the body of the syringe.

9. The injection needle blow-off device according to claim 1, wherein: The adjustable blow-off nozzle is configured to have an adjustable angle of the gas outlet.

10. The injection needle blow-off device according to claim 1, wherein: The adjustable blow-off nozzle includes a body defining a passage between the gas inlet and the gas outlet, the passage being configured to increase at least one of a flow rate of the gas or a pressure of the gas between the gas inlet and the gas outlet.

11. The injection needle blow-off device of claim 1 , further comprising a control circuit system configured to automatically control a blow-off actuator to adjust the position of the blow-off nozzle.

12. A syringe testing device comprising: Gas supply device; An injection needle blowing-off device, the injection needle blowing-off device comprising: a loading surface having a first side configured to contact a syringe and having a second side opposite the first side; an adjustable blow-off nozzle, the adjustable blow-off nozzle being adjacent to the second side of the loading surface, the adjustable blow-off nozzle comprising: a gas inlet configured to be coupled to the gas supply; and a gas outlet configured to direct gas from the gas inlet toward a location of a needle of the syringe, the gas outlet being adjustable to purge the needle within a range of distances from a second side of the loading surface; and A control circuit system is configured to control the gas supply device to output the gas to the adjustable blow-off nozzle.

13. The syringe testing device of claim 12, further comprising a syringe positioner configured to position the syringe, wherein The control circuitry is configured to control the syringe positioner to position the syringe.

14. The syringe testing device according to claim 13, wherein: The syringe positioner is configured to move the body of the syringe into contact with the loading surface.

15. The syringe testing device of claim 12, further comprising a syringe actuator configured to actuate the syringe to expel the contents of the syringe through the needle when the needle of the syringe is adjacent to the adjustable blow-off nozzle, wherein The control circuitry is configured to control the syringe actuator to actuate the syringe.

16. The syringe testing device according to claim 15, wherein: The syringe actuator is configured to actuate the syringe when the body of the syringe contacts the loading surface.

17. The syringe testing device of claim 12, further comprising a collection container configured to collect the contents expelled from the syringe.

18. The syringe testing device according to claim 11, wherein: The loading surface includes a positioning plate having an orifice extending from a first side of the positioning plate to a second side of the positioning plate, and wherein the adjustable blow-off nozzle is configured to have an adjustable distance from the orifice along a plane of the second side of the positioning plate, the gas outlet is configured to purge at a certain angle away from the second side of the positioning plate, and the gas outlet is configured to purge the needle at the position of the needle based on the distance between the adjustable blow-off nozzles and the distance from the orifice in a direction parallel to the second side of the positioning plate.

19. The syringe testing device of claim 11, further comprising a second adjustable blow-off nozzle configured to direct gas toward the needle.

20. The syringe testing device of claim 11, wherein: The gas supply device includes a compressed gas source, a pneumatic pump or a blower.

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