An eye-care liquid for relieving eye fatigue and dryness and a preparation method thereof

Abstract

This invention discloses an eye drop for relieving eye fatigue and dryness, and its preparation method, specifically belonging to the technical field of eye care. The eye drop contains a composition for relieving eye fatigue and dryness, excipients, and a solvent. The composition contains the following components in parts by weight: 20-30 parts of Rhodiola rosea root extract, 10-20 parts of Buddleja officinalis extract, 0.1-0.4 parts of ginger flower extract, and 0.4-0.5 parts of palmarosa extract. The key active ingredients in the composition provided by this invention—Rhodiola rosea root extract, Buddleja officinalis extract, ginger flower extract, and palmarosa extract—can accelerate the improvement of ocular secretions and alleviate lesions of the cornea, iris, and conjunctiva. Furthermore, the combined use of Rhodiola rosea root extract, Buddleja officinalis extract, ginger flower extract, and palmarosa extract has a synergistic effect, achieving multi-dimensional and multi-pathway maintenance of eye health. The eye drop provided by this invention has significant effects in relieving eye fatigue and dryness and improving eye comfort.

Description

Technical Field

[0001] This invention belongs to the technical field of eye care, specifically relating to an eye care solution for relieving eye fatigue and dryness, and its preparation method. Background Technology

[0002] In today's society, with changing lifestyles and the widespread use of electronic devices, eye problems are becoming increasingly prominent, with eye fatigue and dryness becoming common phenomena. Prolonged exposure to computer screens, mobile phones, and other electronic devices keeps the ciliary muscles of the eyes in a state of tension, preventing the eyes from getting sufficient rest and leading to eye fatigue. Simultaneously, environmental factors, aging, and prolonged contact lens wear can reduce tear secretion or cause excessive evaporation, disrupting the stability of the tear film on the eye's surface and consequently causing dry eyes.

[0003] While various eye care products are available on the market to alleviate these problems, they often have limitations. For example, artificial tears only temporarily relieve dryness of the ocular surface and cannot improve ciliary muscle spasm fatigue; frequent use may also disrupt tear film homeostasis. Long-term use of anti-inflammatory drugs (such as cyclosporine A) carries the risk of increased intraocular pressure and corneal damage. Furthermore, many products are not ideal in relieving eye fatigue and dryness, failing to fundamentally address tear deficiency and eye muscle fatigue, thus failing to meet the growing demand for eye health care. Summary of the Invention

[0004] In view of the shortcomings of the prior art, the present invention aims to provide a composition, an eye care product and a method for preparing the same, which can effectively relieve eye fatigue and dryness.

[0005] To achieve the above objectives, the present invention discloses the following technical solutions:

[0006] In a first aspect, the present invention provides a composition for relieving eye fatigue and dryness, wherein the composition contains the following components in parts by weight:

[0007] 20-30 parts of Rhodiola rosea root extract;

[0008] 10-20 parts of Buddleja officinalis extract;

[0009] Ginger flower extract, 0.1-0.4 parts;

[0010] Rose geranium extract 0.4-0.5 parts.

[0011] Preferably, the preparation method of the Rhodiola rosea root extract includes the following steps:

[0012] Step 1-1. Take the dried Rhodiola rosea root, crush it, and sieve it to obtain Rhodiola rosea powder;

[0013] Step 1-2. Mix Rhodiola rosea powder with deionized water at a mass-volume ratio of 1:(15-20)g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation apparatus and distill for 3-4 hours. Select the distilled Rhodiola rosea root hydrosol to obtain the Rhodiola rosea root extract.

[0014] Preferably, the preparation method of the ginger flower extract includes the following steps:

[0015] Step 2-1. Place the dried ginger flower parts in a grinder, grind and sieve to obtain ginger flower powder;

[0016] Step 2-2. Mix ginger flower powder with deionized water at a mass-volume ratio of 1:(30-35)g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation apparatus and distill for 3-4 hours. Select the distilled ginger flower essential oil to obtain the ginger flower extract.

[0017] Preferably, the preparation method of the rosehip extract includes the following steps:

[0018] Step 3-1. Place the dried whole rose grass in a grinder, grind and sieve to obtain rose grass powder;

[0019] Step 3-2. Mix palmarosa powder with deionized water at a mass-volume ratio of 1:(30-35)g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation apparatus and distill for 3-4 hours. Select the distilled palmarosa essential oil to obtain the palmarosa extract.

[0020] Preferably, the preparation method of the Buddleja officinalis extract includes the following steps:

[0021] Step 4-1. Take the dried Buddleja officinalis flower parts, put them into a pulverizer, pulverize and sieve them to obtain Buddleja officinalis powder;

[0022] Step 4-2. Mix the powder of Buddleja officinalis with deionized water at a mass-volume ratio of 1:(15-20)g / mL and soak for 1-1.5h. Then place the mixture in an essential oil distillation device and distill for 3-4h. Select the distilled Buddleja officinalis hydrosol to obtain the Buddleja officinalis extract.

[0023] In a second aspect, the present invention provides an eye care liquid to relieve eye fatigue and dryness, the eye care liquid containing the composition described in the first aspect;

[0024] The composition is added to the eye drops at an amount of 5-10%.

[0025] Preferably, the eye drops also contain excipients and solvents.

[0026] More preferably, the excipient is at least one selected from glycerin, 1,2-hexanediol, methylparaben, cassia gum, acrylate / VP copolymer, sodium hyaluronate, and taurine.

[0027] The solvent is deionized water.

[0028] Thirdly, the present invention provides a method for preparing the eye drops described in the second aspect, the method comprising the following steps:

[0029] Step 5-1. First, add ginger flower extract and rosehip extract to deionized water, add glycerin, and stir at 300-400 r / min for 10-15 min until well mixed. Then add Rhodiola rosea root extract, Buddleja officinalis extract, 1,2-hexanediol, and methylparaben, and stir at 1000-2000 r / min for 10-15 min to obtain mixed solution A.

[0030] Step 5-2. Heat deionized water to 70-80℃, add cassia gum and acrylate / VP copolymer, stir at 300-400 r / min for 20-30 min, cool to 50-60℃, add sodium hyaluronate, and continue stirring at 300-400 r / min for 20-30 min to obtain mixed solution B;

[0031] Step 5-3. Cool mixed solution B to 30-40℃, add mixed solution A and taurine, stir at 300-400r / min for 20-30min, and finally pass through a 300-400 mesh sieve to obtain eye protection solution.

[0032] Fourthly, the present invention provides the use of the composition described in the first aspect in the preparation of eye care products having the effect of relieving eye fatigue and / or relieving eye dryness.

[0033] In this invention:

[0034] Rhodiola rosea is a valuable medicinal plant with effects including enhancing immunity, combating fatigue, improving hypoxia, regulating blood pressure, and promoting blood circulation. This invention uses Rhodiola rosea root as raw material, obtaining Rhodiola rosea root hydrosol through distillation. This hydrosol is rich in flavonoids, terpenoids, sterols, and volatile oils, possessing antioxidant, antibacterial, and anti-inflammatory properties, promoting blood circulation, improving eye comfort, and reducing eye inflammation caused by excessive eye strain.

[0035] The extract of Buddleja officinalis provided by this invention is rich in active substances such as flavonoids, phenylethanol glycosides, and iridoids. It can significantly inhibit lacrimal gland cell apoptosis, promote mucin secretion, and repair the ocular surface mucus layer. At the same time, it can inhibit the release and expression of inflammatory factors, reduce eye itching and congestion, and achieve the effect of improving eyesight.

[0036] The ginger flower extract provided by this invention is rich in volatile active ingredients such as sesquiterpenes, monoterpenes, and oxidized terpenes. It can inhibit bacteria and inflammation, resist oxidative damage, promote blood circulation, and promote transdermal absorption. When combined with other ingredients provided by this invention, the absorption rate of active substances is improved.

[0037] The rosehip extract provided by this invention is rich in active substances such as geraniol, geraniyl acetate, linalool, ocimene, and β-caryophyllene, and has excellent antioxidant, anti-inflammatory, antibacterial, and transdermal permeability promoting properties.

[0038] The beneficial effects of this invention are:

[0039] 1. The composition provided by this invention, with Rhodiola rosea root extract, Buddleja officinalis extract, ginger flower extract and palmarosa extract as key active ingredients, can accelerate the improvement of rabbit eye secretions and reduce lesions of the cornea, iris and conjunctiva. Moreover, when Rhodiola rosea root extract, Buddleja officinalis extract, ginger flower extract and palmarosa extract are used in combination, they have a certain synergistic effect, realizing the maintenance of eye health in multiple dimensions and through multiple pathways.

[0040] 2. The eye drops provided by this invention have significant effects in relieving eye fatigue, dryness, and improving eye comfort. Detailed Implementation

[0041] The technical solution of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0042] To further illustrate the present invention, the following embodiments are provided for detailed description. The raw materials used in the following embodiments and comparative examples of the present invention are all commercially available products.

[0043] Preparation of Rhodiola rosea root extract:

[0044] Step 1-1. Take the dried Rhodiola rosea root and grind it in a grinder through a 30-mesh sieve to obtain Rhodiola rosea powder;

[0045] Step 1-2. Mix Rhodiola crenulata powder with deionized water at a mass-volume ratio of 1:(15-20)g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation apparatus and distill for 3-4 hours. Select the Rhodiola crenulata root hydrosol that has been distilled out, which is the Rhodiola crenulata root extract.

[0046] Preparation of ginger flower extract:

[0047] Step 2-1. Take the dried ginger flower parts and put them into a grinder to grind them through a 30-mesh sieve to obtain ginger flower powder;

[0048] Step 2-2. Mix ginger flower powder with deionized water at a mass-volume ratio of 1:(30-35)g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation device and distill for 3-4 hours. Select the distilled ginger flower essential oil, which is the ginger flower (HEDYCHIUM CORONARIUM) extract.

[0049] Preparation of palmarosa extract:

[0050] Step 3-1. Place the dried whole rose geranium in a grinder and grind it through a 30-mesh sieve to obtain rose geranium powder;

[0051] Step 3-2. Mix palmarosa powder with deionized water at a mass-volume ratio of 1:(30-35)g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation apparatus and distill for 3-4 hours. Select the distilled palmarosa essential oil, which is the palmarosa (CYMBOPOGON MARTINI) extract.

[0052] Preparation of Buddleja officinalis extract:

[0053] Step 4-1. Take the dried Buddleja officinalis flower parts and put them into a pulverizer to grind them through a 30-mesh sieve to obtain Buddleja officinalis powder;

[0054] Step 4-2. Mix the powder of Buddleja officinalis with deionized water at a mass-volume ratio of 1:(15-20)g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation device and distill for 3-4 hours. Select the Buddleja officinalis hydrosol that has been distilled, which is the Buddleja officinalis extract.

[0055] Combination to relieve eye fatigue and dryness

[0056] The active ingredients were compounded according to the mass ratio in Table 1 to obtain a composition that relieves eye fatigue and dryness.

[0057] Table 1. Mass ratio of each component in the composition

[0058] Raw material name Composition 1 Composition 2 Composition 3 Composition 4 Rhodiola rosea root extract 20 25 25 30 Buddleja officinalis extract 20 15 15 10 Ginger flower extract 0.1 0.2 0.3 0.4 Rosehip extract 0.4 0.45 0.45 0.5

[0059] Eye drops 1-4

[0060] Preparation method of eye drops:

[0061] Step 5-1. First, add ginger flower extract and rosehip extract to deionized water, add glycerin, and stir at 300-400 r / min for 10-15 min until well mixed. Then add Rhodiola rosea root extract, Buddleja officinalis extract, 1,2-hexanediol, and methylparaben, and stir at 1000-2000 r / min for 10-15 min to obtain mixed solution A.

[0062] Step 5-2. Heat deionized water to 70-80℃, add cassia seed gum and acrylate / VP copolymer, stir at 300-400 r / min for 20-30 min, cool to 50-60℃, add sodium hyaluronate, and continue stirring at 300-400 r / min for 20-30 min to obtain mixed solution B;

[0063] Step 5-3. Cool mixed solution B to 30-40℃, add mixed solution A and taurine, stir at 300-400r / min for 20-30min, and finally pass through a 300-400 mesh sieve for bottling to obtain eye protection solution.

[0064] The specific percentage of each raw material by mass is shown in Table 2.

[0065] Table 2. Percentage of each ingredient in eye drops (by weight)

[0066]

[0067]

[0068] Note: " / " in the table indicates no addition.

[0069] Performance testing

[0070] Preparation of control group eye drops

[0071] The following compositions 5-8 are based on the formulation of composition 2 with default settings, in order to verify the role of each component in the formulation;

[0072] Table 3 shows the mass ratio of each component in compositions 5-8.

[0073] Raw material name Composition 5 Composition 6 Composition 7 Composition 8 Rhodiola rosea root extract / 40 25 25 Buddleja officinalis extract 40 / 15 15 Ginger flower extract 0.2 0.2 / 0.65 Rosehip extract 0.45 0.45 0.65 /

[0074] Note: " / " in the table indicates no addition.

[0075] The preparation method of the comparative group eye drops refers to the preparation method of the aforementioned eye drops 1-4, and the specific mass percentage of each raw material is as shown in Table 4;

[0076] Table 4 shows the mass percentage of each raw material in comparison groups 1-4.

[0077]

[0078]

[0079] Note: " / " in the table indicates no addition.

[0080] 1. Security Testing

[0081] 1.1 Laboratory animals and their handling

[0082] 1.1.1 Animal Selection and Preparation

[0083] Healthy adult New Zealand rabbits (weight ≥2kg) were selected and acclimatized to the animal facility environment for at least 3 days before the experiment to ensure that their eyes were free of abnormalities (such as redness, swelling, discharge, etc.). Each group used 4 rabbits, and each group was treated with eye drops 1-4 and control groups 1-4. The left eye of each rabbit was used as the test eye, and the right eye was used as the untreated self-control.

[0084] 1.1.2 Administration method

[0085] First, restrain the rabbit. Gently pull back the lower eyelid of the rabbit's test eye and use a micropipette to drop 0.1 mL of the test substance into the conjunctival sac. Passively close the eyelid for 1 second to prevent the test substance from escaping. Do not rinse the eyes within 24 hours. If the test substance is potentially highly irritating, it can be gently rinsed with physiological saline after 24 hours.

[0086] 1.1.3 Supplementary rinsing test (if irritating)

[0087] If the initial test results show that the test substance is irritating, four more rabbits will be used to verify the flushing effect: 30 seconds after the test substance is instilled, the ocular surface will be flushed with sufficient physiological saline at a flow rate of 10 mL / s for at least 30 seconds. Observe the changes in irritation reaction after flushing.

[0088] 1.2 Observation Indicators and Scoring

[0089] 1.2.1 Inspection Time Point

[0090] Eye examinations were performed at 1, 24, 48, and 72 hours after administration, and on days 4 and 7. The experiment could be terminated early if no irritation occurred within 72 hours (total score ≤1).

[0091] 1.2.2 Scoring Criteria

[0092] The cornea, iris, conjunctiva, edema, and secretions of each rabbit's test eye were scored, as shown in the table below:

[0093] Table 5 Stimulus Rating Criteria

[0094]

[0095]

[0096] The scores of the above five items are added together to obtain the total score of monocular stimulation for each rabbit. Finally, the average score of the four rabbits in each group is taken as the stimulation evaluation score for that group.

[0097] 1.2.3 Irritation Classification

[0098] 0-1 points: No irritation; 1-4 points: Mild irritation; 4-7 points: Moderate irritation; >7 points: Severe irritation.

[0099] 1.3 Irritating Results

[0100] In each group of four rabbits, no corneal, iris, or conjunctival lesions, hyperemia, edema, or discharge were observed during examinations at 1 hour, 24 hours, 48 ​​hours, and 72 hours. The total eye irritation score was zero. This indicates that the test substances in eye protection solutions 1-4 and control groups 1-4 are safe and non-irritating.

[0101] 2. Animal efficacy trials

[0102] 2.1 Rabbit model of ultraviolet (UV) eye damage

[0103] Forty-five adult New Zealand rabbits were divided into groups of five and secured with rabbit clips. A 254nm wavelength ultraviolet lamp was placed 40cm in front of the rabbits' eyes, with an irradiation intensity of 5000μW / cm². 2 On the first day, rabbits were irradiated for 3 hours in the morning and 1 hour in the afternoon. On the second and third days, they were irradiated for 2 hours in the morning and 2 hours in the afternoon, for a total of 12 hours, in order to establish a rabbit model of ultraviolet irradiation-induced eye damage.

[0104] 2.2 Grouping and Dosing

[0105] Rabbits were randomly divided into nine groups: eye drops (groups 1-4), control groups (groups 1-4), and a blank control group. Each group was administered the test substance corresponding to the eye drops (groups 1-4), control groups (groups 1-4), and blank control group. Administration was performed immediately after the last irradiation. During administration, the rabbit's eyelids were lifted, and the drug was instilled into the conjunctival sac, held for at least 10 seconds, with the eyelids closed three times in between. One drop (0.05 mL) was instilled into each eye four times daily, with a 2-hour interval, for six consecutive days. The degree of eye damage and ocular secretions were observed before and on day 6 after UV irradiation, and evaluated according to the scoring criteria in Table 5.

[0106] 2.3 Statistical Methods

[0107] Statistical analysis was performed on the data using SPSS 19 software. Paired t-tests or paired rank-sum tests were used to compare the data before and after drug administration. If the data between groups conformed to a normal distribution, a t-test was used; otherwise, a rank-sum test was used. α = 0.05.

[0108] 2.3 Test Results

[0109] Table 6. Experimental Results

[0110] Group Sample quantity n Pre-drug score Post-drug score Eye drops 1 5 11.0±1.6 0.6±0.5*** Eye drops 2 5 10.8±1.3 0.4±0.5*** Eye drops 3 5 11.6±1.7 1.0±0.7*** Eye drops 4 5 11.4±1.7 0.8±0.8*** Comparison Group 1 5 11.0±0.7 3.6±0.5***### Comparison Group 2 5 11.2±1.8 4.0±1.0***### Comparison Group 3 5 10.2±1.5 4.6±1.5***### Comparison Group 4 5 11.2±0.8 5.0±1.0***### Blank group 5 10.2±1.3 9.6±1.5###

[0111] Note: In the table, "***" indicates a highly significant difference between before and after administration (P < 0.001); "###" indicates a highly significant difference compared to the eye drops group 2 (P < 0.001).

[0112] 2.4 Results Analysis

[0113] According to the results in Table 6, the average eye stimulation score of rabbits in the blank group on day 6 was 9.6, which was not significantly different from that before administration. After administration of eye drops 1-4 and control groups 1-4, the eyes of rabbits after UV damage were significantly improved compared with those before administration. This indicates that the key active ingredients of the composition provided by this invention, namely Rhodiola rosea root extract, Buddleja officinalis extract, ginger flower extract and palmarosa extract, can accelerate the improvement of rabbit eye secretions and reduce lesions of the cornea, iris and conjunctiva. Compared with control groups 1-4, eye drops 2 showed significantly better improvement than control groups, indicating that the combination of Rhodiola rosea root extract, Buddleja officinalis extract, ginger flower extract and palmarosa extract has a certain synergistic effect and maintains eye health in multiple dimensions and through multiple pathways.

[0114] 3. Human efficacy test

[0115] 3.1 Experimental Subjects

[0116] Thirty healthy volunteers (20 men and 10 women), aged between 20 and 40, all had symptoms of frequent eye strain (such as dry eyes, blurred vision, and fatigue).

[0117] 3.2 Test substance and grouping

[0118] The test substances were eye drops 2 and commercially available eye ointment.

[0119] Group 2 of eye drops: 15 volunteers used the eye drops prepared by the above method daily.

[0120] Control group: 15 volunteers used commercially available eye ointments (which claimed to relieve dry eyes and eye fatigue).

[0121] 3.3 Usage Method

[0122] Apply an appropriate amount of the test substance evenly around the eyes, including the upper and lower eyelids, with eyes closed. Use once in the morning and once in the evening, keeping the eyes closed for 10 minutes each time to allow for effective absorption.

[0123] 3.4 Evaluation Criteria

[0124] Eye fatigue: assessed using the Visual Acuity Scale (VAS, 0-10, with higher scores indicating greater fatigue);

[0125] Dry eye symptoms: The symptoms are assessed using the subjective assessment scale for dry eye (OSDI scale, with a severity of 0-10, where a higher score indicates greater dryness and discomfort).

[0126] Eye comfort: assessed using a subjective eye comfort rating scale (0-10, with higher scores indicating greater comfort);

[0127] Evaluation data were collected before and after the experiment, and changes in eye fatigue symptoms were recorded. The experimental data are shown in Table 7.

[0128] 3.5 Test Results

[0129] Table 7 Results of changes in eye fatigue symptoms

[0130]

[0131] 3.5 Results Analysis

[0132] The experimental results show that both the eye drops provided by this invention and commercially available eye ointments have certain effects in improving eye fatigue and dryness. Among them, the eye drops provided by this invention show better efficacy compared to commercially available products.

[0133] In summary, the eye drops provided by this invention have significant effects in relieving eye fatigue, dryness, and improving eye comfort.

[0134] Finally, it should be noted that the above descriptions are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A composition for relieving eye fatigue and dryness, characterized in that, The composition contains the following components in parts by weight: 20-30 parts of Rhodiola rosea root extract; 10-20 parts of Buddleja officinalis extract; Ginger flower extract, 0.1-0.4 parts; Rose geranium extract 0.4-0.5 parts; The preparation method of the Rhodiola rosea root extract includes the following steps: Step 1-1. Take the dried Rhodiola rosea root, crush it, and sieve it to obtain Rhodiola rosea powder; Step 1-2. Mix Rhodiola rosea powder with deionized water at a mass-volume ratio of 1:(15-20) g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation device and distill for 3-4 hours. Select the Rhodiola rosea root hydrosol distilled from the distillate to obtain the Rhodiola rosea root extract. The preparation method of the ginger flower extract includes the following steps: Step 2-1. Place the dried ginger flower parts in a grinder, grind and sieve to obtain ginger flower powder; Step 2-2. Mix ginger flower powder with deionized water at a mass-volume ratio of 1:(30-35) g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation device and distill for 3-4 hours. Select the distilled ginger flower essential oil to obtain the ginger flower extract. The preparation method of the rosehip extract includes the following steps: Step 3-1. Place the dried whole rose grass in a grinder, grind and sieve to obtain rose grass powder; Step 3-2. Mix palmarosa powder with deionized water at a mass-volume ratio of 1:(30-35) g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation apparatus and distill for 3-4 hours. Select the distilled palmarosa essential oil to obtain the palmarosa extract. The preparation method of the Buddleja officinalis extract includes the following steps: Step 4-1. Take the dried Buddleja officinalis flower parts, put them into a pulverizer, pulverize and sieve them to obtain Buddleja officinalis powder; Step 4-2. Mix the powder of Buddleja officinalis with deionized water at a mass-volume ratio of 1:(15-20) g / mL and soak for 1-1.5 hours. Then place the mixture in an essential oil distillation device and distill for 3-4 hours. Select the distilled Buddleja officinalis hydrosol to obtain the Buddleja officinalis extract.

2. An eye drop for relieving eye fatigue and dryness, characterized in that, The eye drops contain the composition according to claim 1; The composition is added to the eye drops at an amount of 5-10%.

3. The eye drops according to claim 2, characterized in that, The eye drops also contain excipients and solvents.

4. The eye drops according to claim 3, characterized in that, The excipients are at least one of glycerin, 1,2-hexanediol, methylparaben, cassia gum, acrylate / VP copolymer, sodium hyaluronate and taurine; The solvent is deionized water.

5. The method for preparing the eye drops according to claim 4, characterized in that, The preparation method includes the following steps: Step 5-1. First, add ginger flower extract and rosehip extract to deionized water, add glycerin, and stir at 300-400 r / min for 10-15 min until well mixed. Then add Rhodiola rosea root extract, Buddleja officinalis extract, 1,2-hexanediol, and methylparaben, and stir at 1000-2000 r / min for 10-15 min to obtain mixed solution A. Step 5-2. Heat deionized water to 70-80℃, add cassia gum and acrylate / VP copolymer, stir at 300-400 r / min for 20-30 min, cool to 50-60℃, add sodium hyaluronate, and continue stirring at 300-400 r / min for 20-30 min to obtain mixed solution B; Step 5-3. Cool mixed solution B to 30-40℃, add mixed solution A and taurine, stir at 300-400r / min for 20-30min, and finally pass through a 300-400 mesh sieve to obtain eye protection solution.

6. The use of the composition of claim 1 in the preparation of an eye care product having the effect of relieving eye fatigue and / or relieving dry eyes.

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