Multi-chamber nicotine bag based on essence beads and pH regulator beads

Abstract

The invention relates to a multi-chamber nicotine bag based on essence beads and pH regulator beads, the nicotine bag comprises nicotine powder, beads and a bag, the beads comprise essence beads and pH regulator beads, and the nicotine powder and the beads are packaged in the bag. The pouch may include at least two chambers, and the nicotine powder and the beads are encapsulated in different chambers. Compared with an existing nicotine bag, the nicotine bag has the advantages that the liquid essence and the pH regulator are independently wrapped in the condensate beads, so that volatilization of the essence and chemical inactivation caused by direct contact of the pH regulator and nicotine powder are avoided, and the storage life can be prolonged; and the prominent problems of local over-thick stimulation and insufficient overall release caused by uneven saliva wetting of a traditional nicotine bag are solved.

Description

Technical Field

[0001] This patent belongs to the field of new tobacco, and specifically relates to a multi-chamber nicotine bag based on flavor beads and pH regulator beads. Background Art

[0002] With the continued advancement of global tobacco control policies and rising consumer health awareness, the market demand for new nicotine replacement products, nicotine pouches, has seen explosive growth. Currently, common nicotine pouch products generally use solid powder particle compounding technology. Their basic formula typically consists of nicotine salts, polysaccharide fillers, flavor powders, sweeteners, and pH adjusters. After granulation, the particles are formed and packaged in non-woven bags. This product can deliver nicotine through the oral mucosa, but it still has the following shortcomings:

[0003] 1. Flavor stability defects: Flavor ingredients are directly exposed to the solid powder system and are easily affected by changes in ambient temperature and humidity, as well as oxygen permeation. This accelerates the dissipation of volatile substances and significantly reduces the aroma intensity during the shelf life of the product.

[0004] 2. pH adjustment and slow nicotine release: In the traditional process, pH adjusters and nicotine are released simultaneously in the form of physically mixed powders. The pH value of the oral microenvironment caused by the local wettability of oral saliva does not reach the pH value of the nearest environment, resulting in a non-steady-state release defect of nicotine, which affects the stability and delivery efficiency of nicotine.

[0005] How to improve the edible effect of nicotine pouch products, reduce the loss of flavor, create an optimal pH microenvironment in the oral cavity before nicotine is released, and improve the nicotine release rate and effect are technical problems that need to be solved urgently by those skilled in the art. Summary of the Invention

[0006] To solve the above technical problems, this patent provides a nicotine bag, which includes nicotine powder, beads and a bag, wherein the beads include flavor beads and pH adjuster beads; wherein the nicotine powder and beads are encapsulated in the bag.

[0007] Furthermore, the bag includes at least two chambers, and the nicotine powder and the condensation beads are encapsulated in different chambers.

[0008] Furthermore, the chambers are separated along the thickness of the bag to form a laminated structure.

[0009] Furthermore, the chambers are separated along the length or width of the bag to form a segmented structure.

[0010] Furthermore, the segment structure includes a two-segment structure, a three-segment structure or a four-segment structure.

[0011] Furthermore, the section structure includes:

[0012] Nicotine powder area / bead area

[0013] Nicotine powder area / bead area / nicotine powder area, or

[0014] Bead area / nicotine powder area / bead area, or

[0015] pH regulator bead area / nicotine powder area / flavor bead area, or

[0016] Nicotine powder area / capsule area / nicotine powder area / capsule area, or

[0017] Nicotine powder area / flavor bead area / nicotine powder area / pH adjuster bead area, or

[0018] Nicotine powder area / pH adjuster bead area / nicotine powder area / flavor bead area.

[0019] Furthermore, the stacked structure includes a two-stacked structure, a three-stacked structure, or a four-stacked structure.

[0020] Furthermore, the laminated structure includes:

[0021] Nicotine powder layer / bead layer, or

[0022] Nicotine powder layer / bead layer / nicotine powder layer, or

[0023] Bead layer / nicotine powder layer / bead layer, or

[0024] pH regulator bead layer / nicotine powder layer / flavor bead layer, or

[0025] Nicotine powder layer / bead layer / nicotine powder layer / bead layer, or

[0026] Nicotine powder layer / flavor bead layer / nicotine powder layer / pH adjuster bead layer, or

[0027] Nicotine powder layer / pH adjuster bead layer / nicotine powder layer / flavor bead layer.

[0028] Furthermore, the nicotine powder includes a nicotine component and one or more of a filler, a sweetener, a binder, a humectant, a cooling agent, and a preservative.

[0029] Furthermore, the nicotine component includes one or more of nicotine and nicotine derivatives, the nicotine derivatives include one or more of nicotine salts, nicotine-ion exchange resins, nicotine complexes and non-covalently bound nicotine, and the nicotine salts include one or more of nicotine malate, nicotine citrate, nicotine tartrate, nicotine salicylate, nicotine benzoate and nicotine sulfate.

[0030] Furthermore, the filler includes one or more of cellulose and cellulose derivatives, starch, maltodextrin and cyclodextrin.

[0031] Furthermore, the sweetener includes one or more of white sugar, maltose, corn syrup, lactose, cyclamate, xylitol, aspartame, acesulfame potassium, saccharin, sucralose, mannose and erythritol.

[0032] Furthermore, the binder includes one or more of carboxymethyl cellulose, methyl cellulose, ethyl cellulose, acetyl cellulose, guar gum, gum arabic, agar, gelatin, xanthan gum, chitosan and locust bean gum.

[0033] Furthermore, the moisturizing agent includes one or more of glycerol and ethylene glycol.

[0034] Furthermore, the cooling agent includes one or more of menthol, WS-23, WS-3, menthone glycerol acetal and menthyl lactate.

[0035] Furthermore, the preservative includes one or more of benzoic acid, sodium benzoate, sorbic acid and potassium sorbate.

[0036] Furthermore, the flavor beads include a flavor core liquid and a wall material that wraps the flavor core liquid, wherein the wall material includes one or more of sodium alginate, edible glue or edible grade polyvinyl alcohol.

[0037] Furthermore, the flavor core liquid includes one or more of mint, iced coffee, iced watermelon, iced blueberry, iced orange, iced strawberry, iced honeydew melon, iced mango, bergamot, lemon, grape, peach, strawberry, cherry, and cinnamon flavors.

[0038] Furthermore, the number of essence beads in each chamber is 1 to 3, 3 to 6, or 6 to 9.

[0039] Furthermore, the pH regulator beads include a pH regulator core liquid and a wall material that wraps the pH regulator core liquid; wherein the wall material includes one or more of sodium alginate, edible glue or edible grade polyvinyl alcohol.

[0040] Furthermore, the pH regulator core liquid includes one or more of sodium carbonate, sodium bicarbonate, sodium carbonate + sodium bicarbonate and organic acid salts.

[0041] Furthermore, the number of pH regulator beads in each chamber is 1 to 3, 3 to 6, or 6 to 9.

[0042] Furthermore, the bag is a non-woven bag.

[0043] Compared with existing traditional nicotine bags, the nicotine bag of the present invention has the following effects:

[0044] (1) The components are more stable. The liquid flavor and pH adjuster are independently wrapped in the beads to avoid chemical inactivation caused by volatilization of the flavor and direct contact between the pH adjuster and nicotine powder, which can extend the storage period.

[0045] (2) Precise release: When the bead is bitten, the liquid component can be released instantly, avoiding the "lack of top flavor" problem caused by the slow release of flavors in traditional products. The liquid pH regulator is released first, quickly neutralizing the acidic environment of saliva and wetting the nicotine powder over a large area, so that the oral cavity quickly reaches a suitable weak alkaline environment. The rapid release uniformity is significantly better than that of traditional nicotine bag products. It solves the prominent problems of "local excessive stimulation" and "overall insufficient release" caused by uneven saliva wetting in traditional nicotine bags. BRIEF DESCRIPTION OF THE DRAWINGS

[0046] The above content of this patent and the following specific embodiments will be better understood when read in conjunction with the accompanying drawings. It should be noted that the drawings are only examples of the technical solutions claimed.

[0047] Figure 1 A nicotine pouch according to one embodiment of the present invention is schematically shown, wherein three chambers are separated along the length of the pouch to form a three-section structure, which are, from top to bottom, the condensation bead area / nicotine powder area / condensation bead area;

[0048] Figure 2 A nicotine pouch according to one embodiment of the present invention is schematically shown, wherein three chambers are separated along the thickness of the pouch to form a three-layer structure, which are, from top to bottom, a nicotine powder layer / a condensed bead layer / a nicotine powder layer;

[0049] Figure 3 A nicotine pouch according to one embodiment of the present invention is schematically shown, wherein three chambers are separated along the thickness of the pouch to form a three-layer structure, which are, from top to bottom, a condensation bead layer / nicotine powder layer / condensation bead layer;

[0050] Figure 4 A nicotine pouch according to one embodiment of the present invention is schematically shown, wherein four chambers are separated along the thickness of the pouch to form a four-layer structure, which, from top to bottom, are nicotine powder layer / gel bead layer / nicotine powder layer / gel bead layer;

[0051] Figure 5 A schematic diagram of a nicotine pouch according to one embodiment of the present invention shows four chambers separated along the thickness of the pouch to form a four-layer structure, which, from top to bottom, are: flavoring bead layer / nicotine powder layer / pH adjuster bead layer / nicotine powder layer;

[0052] Figure 6Schematically shows the equipment and process for preparing segmented nicotine pouches;

[0053] Figure 7 The apparatus and process for preparing a laminated nicotine bag are schematically shown. DETAILED DESCRIPTION

[0054] The detailed features and advantages of this patent are described in detail below in the specific implementation method. The content is sufficient to enable any technical personnel in this field to understand the technical content of this patent and implement it accordingly. Based on the description, claims and drawings disclosed in this specification, technical personnel in this field can easily understand the relevant purposes and advantages of this patent.

[0055] " Scope " disclosed herein is limited in the form of lower limit and upper limit, and given range is limited by selecting a lower limit and an upper limit, and the selected lower limit and upper limit define the boundary of special range. The scope limited in this way can be to include end value or not include end value, and can be arbitrarily combined, that is, any lower limit can form a scope with any upper limit combination. For example, if the scope of 60-120 and 80-110 is listed for a particular parameter, it is understood that the scope of 60-110 and 80-120 is also expected. In addition, if the minimum range value 1 and 2 are listed, and if the maximum range value 3,4 and 5 are listed, then the following range can all be expected: 1-3, 1-4, 1-5, 2-3, 2-4 and 2-5. In this application, unless otherwise specified, the numerical range " ab " represents the abbreviation of any real number combination between a and b, wherein a and b are all real numbers. For example, a numerical range of "0-5" indicates that all real numbers between "0-5" are listed herein, and "0-5" is simply an abbreviation for these numerical combinations. Furthermore, when a parameter is expressed as an integer ≥ 2, this is equivalent to disclosing that the parameter is, for example, an integer of 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, etc.

[0056] The terms "include" or "have" have the same meaning as "contain", and also include other forms of the term, such as the gerund form and the singular form in English, meaning including but not limited to, and are not intended to exclude, for example, other elements, components, integers or steps.

[0057] In the description of this patent, it should be noted that the terms "upper", "lower", "left", "right", "inside", "outside", "bottom", "top", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, or the orientations or positional relationships in which the product is usually placed when in use. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, they cannot be understood as limitations on this application.

[0058] All other terms used herein that are not specifically defined in this patent are intended to have the general meanings understood by ordinary technicians in the field to which they belong, and in particular, ordinary technicians in the field can directly and unambiguously determine the meaning of how to implement the technical solution of this patent after reading the claims, description and drawings of this patent.

[0059] Ordinary technical personnel in the relevant field will give priority to reading the claims, description and drawings of this patent to reasonably interpret the terms; secondly, they will choose to refer to the relevant definitions in other documents published by the applicant before the application date to reasonably interpret the terms; thirdly, they will choose to reasonably interpret the terms by referring to the references cited in this patent; finally, they will choose to reasonably interpret the terms by combining the technical dictionaries, technical manuals, reference books, textbooks, national or industry technical standards, etc. commonly used by technical personnel in the relevant technical field.

[0060] This patent provides a nicotine bag, which includes nicotine powder, beads and a bag, wherein the beads include flavor beads and pH adjuster beads; wherein the nicotine powder and beads are encapsulated in the bag.

[0061] In some embodiments, the bag includes at least two chambers, and the nicotine powder and the beads are encapsulated in different chambers. For example, the bag may include two, three, four, five, six or more chambers. The volume of each chamber may be the same or different, for example, the volume of the chamber containing nicotine powder may be larger than the volume of the chamber containing the beads. The flavor beads and the pH adjuster beads may be encapsulated in the same chamber or in different chambers. A chamber may contain a certain proportion of flavor beads and pH adjuster beads, and different chambers may contain mixed beads in different proportions.

[0062] In some embodiments, the nicotine pouch according to the present invention may adopt a segment structure or a laminate structure. In some embodiments, the nicotine pouch according to the present invention may adopt a combination of a segment structure and a laminate structure.

[0063] Segment structure

[0064] In some embodiments, the compartments are separated along the length or width of the bag to form a segmented structure. The separations can be formed by any suitable method known in the art, such as heat sealing, cold sealing, or ultrasonic sealing, etc., preferably heat sealing.

[0065] As used herein, "pouch length or width" generally refers to the two dimensions within the package plane of the nicotine pouch. Typically, the dimension parallel to the horizontal seal is the width, while the dimension perpendicular to the seal is the length. The above definitions are general and should be considered on a case-by-case basis.

[0066] like Figure 1 As shown schematically, the nicotine pouch is divided into three chambers along its length, forming a three-segment structure: from top to bottom, the beading zone, the nicotine powder zone, and the beading zone. Both beading zones contain flavoring beads and pH adjuster beads. The nicotine powder zone is larger than the beading zone to accommodate the nicotine component and one or more of a filler, sweetener, binder, humectant, cooling agent, and preservative.

[0067] Apart from Figure 1 In addition to the structure shown in the figure, the nicotine bag section structure according to the present invention may also include:

[0068] Nicotine powder area / bead area

[0069] Nicotine powder area / bead area / nicotine powder area, or

[0070] pH regulator bead area / nicotine powder area / flavor bead area, or

[0071] Nicotine powder area / capsule area / nicotine powder area / capsule area, or

[0072] Nicotine powder area / flavor bead area / nicotine powder area / pH adjuster bead area, or

[0073] Nicotine powder area / pH adjuster bead area / nicotine powder area / flavor bead area.

[0074] It should be understood that, unless otherwise specified, the "bead zone" refers to the chamber containing both the pH adjuster beads and the fragrance beads.

[0075] The preparation of the segmented nicotine bag can be done by Figure 6 The nicotine bag manufacturing equipment 20 shown is carried out. The nicotine bag manufacturing equipment 20 includes: a packaging material roll 21, a packaging material 22, a feeding port 23, a tube forming mechanism 24, a first seaming mechanism 25 and a second seaming mechanism 26. The non-woven fabric packaging material roll 21 is unfolded into a strip of packaging material 22 and fed into the tube forming mechanism 24, thereby gradually forming a non-woven fabric tube with a tubular structure, and a longitudinal seam 14 is formed by the high-temperature roller on the first seaming mechanism 25 to shape it into a non-woven fabric tube. The feeding pipe 27a, the feeding pipe 27b, and the feeding pipe 27c are used for feeding nicotine powder, flavoring beads, and pH adjuster beads, respectively. Figure 1 Taking the nicotine pouch structure shown as an example, the three feeding pipes are activated sequentially according to the settings to feed the nonwoven fabric. After each feeding, the second seaming mechanism 26 is activated, using its high-temperature clamping block to form a new transverse seam at the upper end of the nonwoven fabric tube. Feeding and transverse sealing are performed alternately, and finally, the zigzag cutting mechanism 29 cuts the nonwoven fabric into segments, thus producing a nicotine pouch product with a segmented structure.

[0076] laminated structure

[0077] In other embodiments, the pouch is separated into chambers along its thickness to form a laminated structure. The separators between the layers can be made of the same material as the pouch, and the sealing locations between the layers can be the same as the transverse seals of the entire nicotine pouch, typically at both ends of the pouch. The sealing between the layers can be performed simultaneously with the transverse sealing of the entire nicotine pouch.

[0078] As used herein, "pouch thickness" generally refers to the dimension perpendicular to the plane of the nicotine pouch packaging. The above definition is only a general definition in the general sense, and the specific situation needs to be judged.

[0079] like Figure 2 As shown schematically, the nicotine pouch is divided into three chambers along the thickness of the pouch to form a three-layer structure, from top to bottom: nicotine powder layer / gel layer / nicotine powder layer. The middle gel layer contains flavoring gel beads and pH adjuster gel beads.

[0080] like Figure 3 As shown schematically, the nicotine bag is divided into three chambers along the thickness of the bag to form a three-layer structure, which are the condensation bead layer / nicotine powder layer / condensation bead layer from top to bottom. Figure 3 In the illustrated embodiment, both sides of the beading layer contain fragrance beads and pH adjuster beads. It is understood that in other embodiments, one side of the beading layer may contain only fragrance beads, while the other side of the beading layer may contain only pH adjuster beads. Alternatively, the ratios of fragrance beads to pH adjuster beads in the two beading layers may differ.

[0081] like Figure 4 As shown schematically, the nicotine pouch is divided into four chambers along its thickness, forming a four-layer structure: nicotine powder layer / gel layer / nicotine powder layer / gel layer, from top to bottom. The middle and side gel layers both contain flavoring beads and pH adjuster beads.

[0082] like Figure 5 As shown schematically, the nicotine bag is divided into four chambers along the thickness of the bag to form a four-layer structure, which are, from top to bottom, flavoring bead layer / nicotine powder layer / pH adjuster bead layer / nicotine powder layer. Figure 5 In a preferred embodiment of the present invention, the pH adjuster bead layer is located between two nicotine powder layers. During use, biting the pH adjuster bead allows the pH adjuster to quickly wet the nicotine powder, promoting stable and rapid nicotine release. The flavor bead layer is located on the outer layer, achieving chew-triggered instantaneous release, avoiding the "lack of upfront flavor" problem caused by the slow release of flavors in traditional products.

[0083] Apart from Figure 2-5 In addition to the structure shown in FIG. 1 , the nicotine bag laminate structure according to the present invention may further include:

[0084] Nicotine powder layer / bead layer, or

[0085] pH regulator bead layer / nicotine powder layer / flavor bead layer, or

[0086] Nicotine powder layer / bead layer / nicotine powder layer / bead layer, or

[0087] Nicotine powder layer / pH adjuster bead layer / nicotine powder layer / flavor bead layer.

[0088] It should be understood that, unless otherwise specified, the "beading layer" refers to the chamber containing both the pH adjuster beads and the fragrance beads.

[0089] The preparation of the laminated nicotine bag can be done by Figure 7 The nicotine bag manufacturing device 30 shown schematically is carried out. Figure 7 As shown, the nicotine bag manufacturing equipment 30 includes: three packaging material guide rollers (more packaging material guide rollers can be provided as needed), namely 31a, 31b and 31c, which are respectively used to guide three layers of non-woven fabrics 32a, 32b and 32c (more layers of non-woven fabrics can be provided as needed); condensed beads 16 and nicotine powder 15 are respectively placed on the non-woven fabrics 32a and 32b, and conveyed to the bottom of the hot pressing mold 34 by the conveyor belt 33; when it is detected that the material has moved to a specific position below the hot pressing mold, the conveyor belt is paused, and the hot pressing mold 34 is pressed down and heated. A circle of seal is formed on the multiple layers of non-woven fabrics around the material through molding and heating, and the material is pressed into a bag, which is then cut to form a laminated structure nicotine bag 10.

[0090] Nicotine ingredients

[0091] In the present invention, the nicotine component is the main functional component in the nicotine powder.

[0092] The nicotine component may include one or more of nicotine and nicotine derivatives.

[0093] As used herein, "nicotine", commonly known as nicotine, is an organic compound with the chemical formula C 10 H 14 N2, the structural formula is shown in Formula I. Nicotine belongs to the alkaloid class of compounds. Alkaloids are a class of nitrogen-containing alkaline organic molecules with alkaline-like chemical properties that can form salt solutes in water or react with acids. Nicotine contains pyridine and pyrrolidine rings, and its nitrogen atoms are easily receptive to protons (H +), is alkaline and can react with acids to form salt compounds. Free nicotine has a high pH (approximately 8.0-10.0) and can be highly irritating to the oral and throat mucosa. Nicotine salts significantly reduce irritation by lowering the pH (approximately 5.0-7.0), providing a gentler user experience.

[0094]

[0095] Nicotine derivatives include one or more of nicotine salts, nicotine-ion exchange resins, nicotine complexes, and non-covalently bound nicotine.

[0096] Nicotine salts include nicotine hydrochloride, nicotine phosphate, nicotine sulfate, nicotine pyruvate, nicotine formate, nicotine oxalate, nicotine ascorbate, nicotine glycolate, nicotine acetate, nicotine isovalerate, nicotine valerate, nicotine propionate, nicotine octanoate, nicotine lactate, nicotine levulinate, nicotine sorbate, nicotine malate, nicotine fumarate, nicotine salicylate, nicotine glycinate, nicotine tartrate, nicotine succinate, nicotine citrate, nicotine benzoate, nicotine oleate One or more of nicotine salts, nicotine aconitate, nicotine butyrate, nicotine cinnamate, nicotine decanoate, nicotine 3,7-dimethyl-6-octenoate, nicotine 1-glutamate, nicotine heptanoate, nicotine hexanoate, nicotine 3-hexenoate, nicotine trans-2-hexenoate, nicotine isobutyrate, nicotine laurate, nicotine 2-methylbutyrate, nicotine 2-methylvalerate, nicotine myristate, nicotine nonanoate, nicotine palmitate, nicotine 4-pentenoate, nicotine phenylacetate, and nicotine 3-phenylpropionate.

[0097] Based on the total weight of the nicotine powder, the weight percentage of the nicotine component may be 0.05% to 0.10%, 0.05% to 0.07%, 0.07% to 0.09%, 0.09% to 0.10%, 0.10% to 0.20%, 0.20% to 0.50%, 0.50% to 0.75%, 0.75% to 1% or 1% to 5%.

[0098] Other additives

[0099] In the present invention, in addition to the nicotine component, the nicotine powder may further include one or more additives, for example, fillers, sweeteners, binders, humectants, cooling agents, and preservatives.

[0100] The filler may include one or more of cellulose and cellulose derivatives, starch, maltodextrin, and cyclodextrin. For example, the filler is microcrystalline cellulose. The weight percentage of the filler, based on the total weight of the nicotine powder, may be 40% to 45%, 45% to 50%, 50% to 55%, 55% to 60%, 60% to 65%, 65% to 70%, 70% to 75%, 75% to 80%, or 80% to 85%.

[0101] The sweetener may include one or more of white sugar, maltose, corn syrup, lactose, sodium cyclamate, xylitol, aspartame, acesulfame potassium, saccharin, sucralose, mannose, and erythritol. Based on the total weight of the nicotine powder, the weight percentage of the sweetener may be 40% to 45%, 45% to 50%, 50% to 55%, 55% to 60%, 60% to 65%, 65% to 70%, 70% to 75%, 75% to 80%, or 80% to 85%.

[0102] The binder may include one or more of carboxymethyl cellulose, methyl cellulose, ethyl cellulose, acetyl cellulose, guar gum, gum arabic, agar, gelatin, xanthan gum, chitosan, and carob gum. The binder may be present in an amount of 0.5% to 1.0%, 1.0% to 1.5%, 0.5% to 2.0%, 2.0% to 3.0%, or 3.0% to 5.0% by weight based on the total weight of the nicotine powder.

[0103] The humectant may include one or more of glycerol and ethylene glycol. Based on the total weight of the nicotine powder, the weight percentage of the humectant may be 5% to 10%, 10% to 15%, 15% to 18%, 18% to 20%, 20% to 25% or 25% to 30%.

[0104] Cooling agents may include one or more of menthol, WS-23, WS-3, menthone glycerol acetal and menthyl lactate. Menthol: Especially L-menthol, is the most common cooling agent, but it has a strong odor and is irritating to the skin and mucous membranes. WS-23: Chemical name N,2,3-trimethyl-2-(1-methylethyl) butanamide, characterized by long-lasting cooling, no bitterness or irritation, high temperature resistance (200°C does not affect the effect), and is widely used in food, tobacco, etc. WS-3 (N-ethyl-p-menthyl-3-carboxamide): It can be mixed with peppermint oil to enhance the cooling effect. It is a white crystal. Menthone glycerol acetal (Frescolat MGA): It comes in two specifications, racemic and L-rotatory, and has a long-lasting cooling effect. Menthyl lactate: It is almost odorless, but can provide a long-lasting cooling sensation. Based on the total weight of the nicotine powder, the weight percentage of the cooling agent may be 0.10% to 0.20%, 0.20% to 0.50%, 0.50% to 0.75%, 0.75% to 1%, or 1% to 5%.

[0105] The preservative may include one or more of benzoic acid, sodium benzoate, sorbic acid, and potassium sorbate. Based on the total weight of the nicotine powder, the weight percentage of the preservative may be 0.05% to 0.10%, 0.05% to 0.07%, 0.07% to 0.09%, 0.09% to 0.10%, 0.10% to 0.20%, 0.20% to 0.50%, 0.50% to 0.75%, 0.75% to 1%, or 1% to 5%.

[0106] Gel beads

[0107] The "gel beads" according to the present invention include a core liquid (liquid) and a wall material (membrane) that wraps the core liquid.

[0108] The particle size of the beads according to the present invention may be 1.0 to 2.0 mm, 2.0 to 3.0 mm, 3.0 to 4.0 mm, 4.0 to 5.0 mm, 5.0 to 6.0 mm, or 6.0 to 8.0 mm.

[0109] The thickness of the wall material of the beads according to the present invention may be 0.01 to 0.05 mm, 0.05 to 0.10 mm, 0.10 to 0.20 mm, 0.20 to 0.50 mm, or 0.50 to 1.00 mm.

[0110] The wall material may include one or more of sodium alginate, edible gum (eg, carrageenan, guar gum, gelatin), or edible grade polyvinyl alcohol.

[0111] The essence condensation beads include essence core liquid and wall material wrapping the essence core liquid.

[0112] The flavor core liquid may include one or more of mint, iced coffee, iced watermelon, iced blueberry, iced sweet orange, iced strawberry, iced honeydew melon, iced mango, bergamot, lemon, grape, peach, strawberry, cherry, cinnamon, and blueberry flavors.

[0113] The number of essences can be 1 to 3, 3 to 6, or 6 to 9 per chamber.

[0114] The pH adjuster beads include a pH adjuster core liquid and a wall material that wraps the pH adjuster core liquid.

[0115] The pH adjuster core solution may include one or more of sodium carbonate, sodium bicarbonate, sodium carbonate + sodium bicarbonate, and organic acid salts (eg, acetate, lactate, glycinate, gluconate, and citrate).

[0116] The number of pH regulator beads can be 1 to 3, 3 to 6, or 6 to 9.

[0117] bag

[0118] The bag according to the present invention can be made of a woven material, a nonwoven material, and / or a composite material comprising a woven material and a nonwoven material, or tissue paper. The bag according to the present invention is a saliva-permeable bag. Preferably, the bag is a nonwoven bag. The bag can be prepared using methods known in the art, and the sealing can be performed by heat sealing, cold sealing, ultrasonic sealing, etc.

[0119] Example

[0120] Experimental materials and equipment

[0121] Nicotine salt in this experiment was provided by Hubei Xinye Tobacco Sheet Development Co., Ltd.; microcrystalline cellulose (Huzhou Linghu Xinwang Chemical Co., Ltd.); potassium sorbate (Maohesheng Zhongchen Biological Company); sucralose (Anhui Jinhe Industrial Co., Ltd.); acesulfame potassium (Anhui Jinhe Industrial Co., Ltd.); guar gum, xylitol, modified starch (Jiahe Food Industry Co., Ltd.); menthol (Hubei Xinye Tobacco Sheet Development Co., Ltd.); plant fibers (Canadian cyperus and Brazilian parrot); sodium bicarbonate and sodium carbonate (Guangdong Guangtai Food Technology Co., Ltd.); glycerin, propylene glycol, WS-23, and various flavors were provided by Wuhan Yellow Crane Tower Flavors and Fragrances Co., Ltd.; and non-woven fabrics (Shanghai Duquesne Flowers Co., Ltd.). Nicotine powder was mixed using a three-dimensional mixer (Shanghai Yuming Instrument Co., Ltd.); nicotine beads were prepared using a pulse dripping device (DDW-1000S) and packaged in a nicotine pouch packaging machine (Sidsaim, India).

[0122] Preparation method of gel beads

[0123] Step (1): uniformly stirring the selected essence liquid or pH regulator, and ultrasonically degassing at a power of 1000W for 10 minutes to obtain a bead core liquid;

[0124] Step (2): 5 parts of sodium alginate, 200 parts of agar, 150 parts of gellan gum, 100 parts of glycerin, and 10,000 parts of deionized water were mixed uniformly by high-speed stirring, and then stirred at 1,000 r / min for 20 minutes. After standing for 20 minutes, a bead wall material glue solution was prepared;

[0125] Step (3): Using a pulse dripping device, drip the core liquid of the beads through a nozzle into the glue of the bead wall material. The core liquid of the beads quickly solidifies in the glue of the bead wall material, forming tiny spherical capsules. The beads after dripping are placed in a cleaning device and cleaned with solvent ethanol. The cleaned beads are placed in a drying device and dried with hot air to remove moisture. The dried beads are placed in a constant temperature and humidity environment and allowed to stand for a period of time.

[0126] Nicotine powder preparation

[0127] Mix the ingredients shown in the table below to get nicotine powder

[0128] Table 1. Nicotine Powder A

[0129]

[0130]

[0131] Table 2. Nicotine Powder B

[0132] Component 2 Weight percentage Nicotine ingredients Nicotine tartrate 0.5％ Fillers microcrystalline cellulose 79.65％ sweeteners Acesulfame K 0.20％ Adhesives guar gum 2.00％ moisturizer Propylene glycol 15.00％ cooling agent Menthol 2.50％ preservative Potassium sorbate 0.15％

[0133] Table 3. Nicotine Powder C

[0134] Component 3 Weight percentage Nicotine ingredients Nicotine citrate 0.05％ Fillers plant fiber 79.10％ sweeteners Xylitol 0.50％ Adhesives modified starch 2.00％ moisturizer Propylene glycol 18.00％ cooling agent WS-3 0.20％ preservative Potassium sorbate 0.15％

[0135] Nicotine pouch preparation

[0136] Table 4. Composition of nicotine pouches

[0137] Components quantity Nicotine powder Nicotine Powder A 6g pH Adjuster Beads Sodium bicarbonate and sodium carbonate beads 2 pieces Fragrance beads Mint Essence Gel Beads 3 pieces

[0138] The above nicotine bag composition is used to prepare a nicotine bag using a nicotine bag packaging machine according to the following nicotine bag structure:

[0139] Table 5. Nicotine pouch structure

[0140] serial number structure Structural Description Comparative Example 1 Single chamber bag Nicotine pouches and pods are placed in the same chamber Example 1 Segment structure pH Regulator Beads / Nicotine Powder / Flavor Beads Example 2 Laminated structure Nicotine powder (3g) / flavor beads / nicotine powder (3g) / pH adjuster beads Example 3 Laminated structure Flavoring beads / nicotine powder (3g) / pH adjuster beads / nicotine powder (3g)

[0141] Artificial sensory evaluation experiment

[0142] The evaluation was conducted by 5 evaluators. During the experiment, each evaluator placed the nicotine bag sample on the upper lip and gums of the mouth and filled out a questionnaire on the cooling intensity, stimulation intensity and flavor taste.

[0143] Table 6. Manual sensory evaluation of nicotine pouch in Example 1 (10-point system)

[0144] Evaluators Cooling intensity Stimulus intensity Flavor and taste Person 1 8.9 7 8.5 Person 2 8.5 7.5 9 Person 3 9 7 9 Person 4 8.8 6.5 8.5 Person 5 9 7.5 8.5 average 8.8 7.1 8.7

[0145] Table 7. Manual sensory evaluation of nicotine pouch in Example 2 (10-point system)

[0146] Evaluators Cooling intensity Stimulus intensity Flavor and taste Person 1 8 8.5 8 Person 2 7.5 9 8.5 Person 3 8.5 9 8 Person 4 8 9 8 Person 5 7.5 9 7.5 average 7.9 8.9 8.0

[0147] Table 8. Manual sensory evaluation of nicotine pouch in Example 3 (10-point system)

[0148] Evaluators Cooling intensity Stimulus intensity Flavor and taste Person 1 9 8.5 9 Person 2 9 9 8.5 Person 3 8.5 8 8.5 Person 4 9 8 9 Person 5 9 8 9.5 average 8.9 8.3 8.9

[0149] Table 9. Human sensory evaluation of nicotine bag of comparative example 1 (10 points system)

[0150] Evaluators Cooling intensity Stimulus intensity Flavor and taste Person 1 6 7 7 Person 2 7 7.5 8 Person 3 8 7 8 Person 4 6.5 6.5 7.5 Person 5 6 7.5 7 average 6.7 7.1 7.5

[0151] The terms and expressions used in this specification are intended to be illustrative rather than restrictive, and in the use of these terms and expressions, there is no intention to exclude any equivalents of the features shown and described or portions thereof, but it should be recognized that various variations are possible within the scope of the protection claimed in this patent. It should therefore be understood that although this patent has been specifically disclosed through preferred embodiments, exemplary embodiments, and optional features, those skilled in the art may adopt variations or modifications of the concepts disclosed in this specification, and such variations and modifications are therefore considered to be within the scope of this patent as defined by the appended claims. The specific embodiments given in this specification are examples of useful embodiments of this patent, and it is obvious to those skilled in the art that many variations of the devices, device components, and method steps disclosed in this specification can be used to implement this patent.

[0152] The foregoing description of the specific embodiments fully discloses the general features of this patent so that others can easily modify and / or adapt such specific embodiments for various applications by applying knowledge within the technical scope of the art without undue experimentation and without departing from the general concept of this patent. Therefore, based on the teachings and guidance given herein, it is intended that such adaptations and modifications be included within the meaning and range of equivalents of the disclosed embodiments. It should be understood that the words or terms used herein are for descriptive purposes only and are not intended to be limiting, and thus the words or terms of this specification will be interpreted by those skilled in the art based on the above teachings and guidance.

[0153] Additionally, the scope of this patent should not be limited by any of the above-described exemplary embodiments, but should be defined only in accordance with the following claims and their equivalents.

Claims

1. A nicotine bag, characterized in that: The nicotine bag includes nicotine powder, beads and a bag. Wherein, the gel beads include essence gel beads and pH regulator gel beads; The nicotine powder and the beads are packaged in the bag.

2. The nicotine bag according to claim 1, characterized in that The bag comprises at least two chambers, and the nicotine powder and the pods are encapsulated in different chambers.

3. The nicotine bag according to claim 2, characterized in that The chambers are divided along the length or width of the bag to form a segmented structure.

4. The nicotine bag according to claim 3, characterized in that The segment structure includes a two-segment structure, a three-segment structure or a four-segment structure; The segment structure includes: Nicotine powder area / bead area Nicotine powder area / bead area / nicotine powder area, or Bead area / nicotine powder area / bead area, or pH regulator bead area / nicotine powder area / flavor bead area, or Nicotine powder area / capsule area / nicotine powder area / capsule area, or Nicotine powder area / flavor bead area / nicotine powder area / pH adjuster bead area, or Nicotine powder area / pH adjuster bead area / nicotine powder area / flavor bead area.

5. The nicotine bag according to claim 2, characterized in that The chambers are separated along the thickness of the bag to form a laminate structure.

6. The nicotine bag according to claim 5, characterized in that The stacked structure includes a two-stacked structure, a three-stacked structure or a four-stacked structure; The laminated structure comprises: Nicotine powder layer / bead layer, or Nicotine powder layer / bead layer / nicotine powder layer, or Bead layer / nicotine powder layer / bead layer, or pH adjuster bead layer / nicotine powder layer / flavor bead layer, or Nicotine powder layer / bead layer / nicotine powder layer / bead layer, or Nicotine powder layer / flavor bead layer / nicotine powder layer / pH adjuster bead layer, or Nicotine powder layer / pH adjuster bead layer / nicotine powder layer / flavor bead layer.

7. The nicotine bag according to claim 1, characterized in that The nicotine powder comprises a nicotine component and one or more of a filler, a sweetener, a binder, a humectant, a cooling agent and a preservative; The nicotine component includes one or more of nicotine and nicotine derivatives, the nicotine derivatives include one or more of nicotine salts, nicotine-ion exchange resins, nicotine complexes and non-covalently bound nicotine, and the nicotine salts include one or more of nicotine malate, nicotine citrate, nicotine tartrate, nicotine salicylate, nicotine benzoate and nicotine sulfate; The filler comprises one or more of cellulose and cellulose derivatives, starch, maltodextrin and cyclodextrin; The sweetener includes one or more of white sugar, maltose, corn syrup, lactose, sodium cyclamate, xylitol, aspartame, acesulfame potassium, saccharin, sucralose, mannose and erythritol; The binder comprises one or more of carboxymethyl cellulose, methyl cellulose, ethyl cellulose, acetyl cellulose, guar gum, gum arabic, agar, gelatin, xanthan gum, chitosan and locust bean gum; The moisturizing agent includes one or more of glycerol and ethylene glycol; The cooling agent includes one or more of menthol, WS-23, WS-3, menthone glycerol acetal and menthyl lactate; The preservative includes one or more of benzoic acid, sodium benzoate, sorbic acid and potassium sorbate.

8. The nicotine bag according to claim 1, characterized in that The flavor beads include a flavor core liquid and a wall material that wraps the flavor core liquid, wherein the wall material includes one or more of sodium alginate, edible glue, or edible-grade polyvinyl alcohol; the flavor core liquid includes one or more of mint, iced coffee, iced watermelon, iced blueberry, iced orange, iced strawberry, iced honeydew melon, iced mango, bergamot, lemon, grape, peach, strawberry, cherry, and cinnamon flavors; the number of flavor beads in each chamber is 1 to 3, 3 to 6, or 6 to 9.

9. The nicotine bag according to claim 1, characterized in that The pH regulator beads include a pH regulator core liquid and a wall material that wraps the pH regulator core liquid; wherein the wall material includes one or more of sodium alginate, edible glue, or edible-grade polyvinyl alcohol; the pH regulator core liquid includes one or more of sodium carbonate, sodium bicarbonate, sodium carbonate + sodium bicarbonate, and organic acid salts; the number of pH regulator beads per chamber is 1 to 3, 3 to 6, or 6 to 9.

10. The nicotine bag according to claim 1, characterized in that The bag is a non-woven bag.

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