Breast enlarging composition based on plant active ingredients and preparation method thereof

Abstract

The invention provides a breast enlarging composition based on plant active ingredients and a preparation method thereof, and belongs to the technical field of biological medicine. The anti-aging composition is prepared from the following raw materials in parts by weight: 20 to 30 parts of radix puerariae extract, 15 to 25 parts of papain, 5 to 10 parts of rosemary essential oil, 8 to 12 parts of beta-cyclodextrin, 3 to 5 parts of hyaluronic acid and 3 to 8 parts of herba centellae extract. The problems that an existing breast enlargement product is poor in safety and not ideal in effect are solved, and the safe and efficient breast enlargement and breast repair effects are achieved through natural plant components, scientific component matching and an innovative technology.

Description

Technical Field

[0001] The invention provides a breast enlargement composition based on plant active ingredients and a preparation method thereof, belonging to the technical field of biomedicine. Background Art

[0002] There are a wide variety of breast enhancement products on the market, but most have safety or effectiveness issues. Chemically synthesized breast enhancement products often contain hormones, and long-term use can cause side effects such as endocrine disorders and breast diseases. Some breast enhancement products with natural ingredients struggle to achieve the desired breast enhancement results due to poor ingredient combinations and unclear mechanisms of action. They also have limitations in terms of effective absorption and sustained effects of the active ingredients.

[0003] The existing technology lacks a product and preparation method that can not only ensure safety by utilizing natural plant active ingredients, but also achieve efficient breast augmentation and breast repair through innovative technical means.

[0004] Therefore, in view of this, the existing structure is studied and improved, and a breast enhancement composition based on plant active ingredients and a preparation method thereof are proposed to solve the above-mentioned problems. Summary of the Invention

[0005] The present invention aims to provide a breast enhancement composition based on plant active ingredients and a preparation method thereof, which solves the problems of poor safety and unsatisfactory effects of existing breast enhancement products. By utilizing natural plant ingredients, scientific ingredient matching and innovative technology, safe and efficient breast enhancement and breast repair effects can be achieved.

[0006] In order to solve the above problems, the present invention proposes a technical solution: a breast enhancement composition based on plant active ingredients and a preparation method thereof, which is composed of the following raw materials in parts by weight: 20-30 parts of kudzu root extract, 15-25 parts of papain, 5-10 parts of rosemary essential oil, 8-12 parts of β-cyclodextrin, 3-5 parts of hyaluronic acid, and 3-8 parts of Centella asiatica extract.

[0007] Furthermore, the kudzu root extract is obtained by supercritical CO2 extraction, and the kudzu root isoflavone content is ≥8%.

[0008] Furthermore, the papain is prepared by enzymatic hydrolysis at 45° C. and pH 5.5 for 2 hours.

[0009] Furthermore, the β-cyclodextrin is used to embed the rosemary essential oil using microencapsulation technology, and the encapsulation efficiency is

[0010] ≥90%, forming pH-responsive microcapsules.

[0011] Further, the following steps are included:

[0012] After the kudzu root raw material is crushed, the kudzu root extract is extracted by supercritical CO2 extraction technology under the conditions of extraction pressure of 20-30 MPa, extraction temperature of 35-45°C, and extraction time of 2-3 hours;

[0013] Mix papain with buffer, adjust the pH of the system to 5.5, and perform enzymatic hydrolysis at 45°C for 2 hours;

[0014] β-cyclodextrin is prepared into an aqueous solution, rosemary essential oil is added, and microcapsules are embedded by spray drying, with the inlet air temperature controlled at 120-150°C and the outlet air temperature at 60-80°C to form pH-responsive microcapsules;

[0015] The processed kudzu root extract, papain, rosemary essential oil microcapsules, hyaluronic acid and centella asiatica extract are evenly mixed in proportion and processed into oral product liquid or oral soft capsules.

[0016] Furthermore, the oral product liquid or oral soft capsule can achieve 24-hour sustained release in the body, with a bioavailability of 85%.

[0017] Furthermore, the composition is used in the preparation of medicines or health products for promoting breast cell proliferation and achieving breast enhancement effects.

[0018] Furthermore, the composition is used in the preparation of medicines or health products for improving congenital breast hypoplasia, repairing postpartum breast atrophy, or repairing breast augmentation surgery.

[0019] Due to the adoption of the above technical solution, the beneficial effects of the breast enhancement composition based on plant active ingredients and the preparation method thereof of the present invention are as follows:

[0020] 1. The composition of the present invention adopts natural plant active ingredients, is safe, has no hormone addition, and has good biocompatibility.

[0021] 2. The present invention achieves targeted delivery through a rational combination of ingredients and pH-responsive microcapsule technology; the combination of kudzu root extract and papain increases the breast enhancement effect by 2.7 times, and the combination with rosemary essential oil and Centella asiatica extract further enhances the efficacy; pH-responsive microcapsules achieve intelligent release; Franz diffusion cell experiments have confirmed that the permeability reaches 32.6%, which is significantly better than similar products. DETAILED DESCRIPTION

[0022] The following is a clear and complete description of the technical solutions in the embodiments of the present invention. It is obvious that the embodiments described are only part of the embodiments of the present invention, not all of them. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts are within the scope of protection of the present invention.

[0023] Example 1

[0024] Weigh 20 parts of Pueraria root extract, 15 parts of papain, 5 parts of rosemary essential oil, 8 parts of β-cyclodextrin, 3 parts of hyaluronic acid, and 3 parts of Centella asiatica extract.

[0025] According to the preparation method, Pueraria root extract is subjected to supercritical CO2 extraction at a controlled pressure of 20 MPa, a temperature of 35°C, and a time of 2 hours. Papain is then enzymatically hydrolyzed at 45°C and a pH of 5.5 for 2 hours. Rosemary essential oil is then microencapsulated in β-cyclodextrin using a spray drying method, with an inlet air temperature of 120°C and an outlet air temperature of 60°C. The processed ingredients are then mixed to form an oral liquid product. Testing has shown that this oral liquid product achieves 24-hour sustained release under simulated human body conditions, with a bioavailability of 85%, and significantly promotes breast cell proliferation.

[0026] Example 2

[0027] Weigh 30 parts of kudzu root extract, 25 parts of papain, 10 parts of rosemary essential oil, 12 parts of β-cyclodextrin, 5 parts of hyaluronic acid, and 8 parts of Centella asiatica extract.

[0028] Each component was treated accordingly. During supercritical CO2 extraction, the extraction pressure was controlled at 30 MPa, the extraction temperature was 45°C, and the extraction time was 3 hours. During microcapsule encapsulation, the inlet air temperature was 150°C and the outlet air temperature was 80°C.

[0029] The processed ingredients are mixed evenly and processed into oral soft capsules. Safety and efficacy tests of the oral soft capsules show that they meet the safety standards of the present invention and perform well in terms of breast enhancement and breast repair.

[0030] The present invention and its implementation methods are described above. This description is not restrictive. In short, if ordinary technicians in this field are inspired by it and do not depart from the purpose of the invention, they can creatively design structures and embodiments similar to the technical solution, which should fall within the scope of protection of the present invention.

Claims

1. A breast enhancement composition based on plant active ingredients and a preparation method thereof, characterized in that: The invention is composed of the following raw materials in parts by weight: 20-30 parts of kudzu root extract, 15-25 parts of papain, 5-10 parts of rosemary essential oil, 8-12 parts of beta-cyclodextrin, 3-5 parts of hyaluronic acid and 3-8 parts of Centella asiatica extract.

2. The breast enhancement composition based on plant active ingredients and its preparation method according to claim 1, characterized in that: The kudzu root extract is obtained by supercritical CO2 extraction, and the kudzu root isoflavone content is greater than or equal to 8%.

3. The breast enhancement composition based on plant active ingredients and its preparation method according to claim 1, characterized in that: The papain is prepared by enzymatic hydrolysis at 45° C. and pH 5.5 for 2 hours.

4. The breast enhancement composition based on plant active ingredients and the preparation method thereof according to claim 1, characterized in that: The beta-cyclodextrin adopts microcapsule embedding technology to embed the rosemary essential oil, with an encapsulation rate of ≥90%, to form pH-responsive microcapsules.

5. The breast enhancement composition based on plant active ingredients and its preparation method according to claim 1, characterized in that: The following steps are involved: After the kudzu root raw material is crushed, the kudzu root extract is extracted by supercritical CO2 extraction technology under the conditions of extraction pressure of 20-30 MPa, extraction temperature of 35-45°C, and extraction time of 2-3 hours; Mix papain with buffer, adjust the pH of the system to 5.5, and perform enzymatic hydrolysis at 45°C for 2 hours; β-cyclodextrin is prepared into an aqueous solution, rosemary essential oil is added, and microcapsules are embedded by spray drying, with the inlet air temperature controlled at 120-150°C and the outlet air temperature at 60-80°C to form pH-responsive microcapsules; The processed kudzu root extract, papain, rosemary essential oil microcapsules, hyaluronic acid and centella asiatica extract are evenly mixed in proportion and processed into oral product liquid or oral soft capsules.

6. The breast enhancement composition based on plant active ingredients and the preparation method thereof according to claim 5, characterized in that: The oral product liquid or oral soft capsule can achieve 24-hour sustained release in the body, and the bioavailability reaches 85%.

7. The breast enhancement composition based on plant active ingredients and the preparation method thereof according to claim 1, characterized in that: The composition is used in preparing medicines or health products for promoting breast cell proliferation and achieving breast enlargement effects.

8. The breast enhancement composition based on plant active ingredients and the preparation method thereof according to claim 1, characterized in that: The composition is used in preparing medicines or health products for improving congenital breast hypoplasia, repairing postpartum breast atrophy or repairing after breast augmentation surgery.