Device for feeding drug to far end in coronary artery through targeted perfusion catheter

Abstract

The invention belongs to the technical field of medical instruments, and particularly relates to a device for feeding medicine into the coronary artery far-end of a catheter through targeted irrigation, which comprises a medicine feeder, a protective cylinder fixedly connected to the side surface of the medicine feeder, a pushing mechanism arranged in the medicine feeder and used for pushing liquid medicine, a medicine feeding mechanism connected to the bottom end of the medicine feeder, an auxiliary cylinder fixedly arranged in the protective cylinder, and a medicine feeding mechanism arranged in the auxiliary cylinder. An electric push rod is fixedly arranged in the protection cylinder, a compression block is arranged in the auxiliary cylinder, and a conveying pipe is arranged on the side face of the auxiliary cylinder. According to the device, the auxiliary cylinder is adopted, so that liquid medicine can be conveniently conveyed and treated, a conveying pipe is not sealed any more, an electric push rod works to drive a compression block to move, the liquid medicine can flow into the medicine feeding mechanism, the liquid medicine is continuously conveyed through the medicine feeding mechanism, and in this way, the working time can be shortened, and the working efficiency can be improved. The working efficiency is improved, the liquid medicine can be conveniently and rapidly replaced for conveying treatment, and the working efficiency of the device for feeding the medicine into the coronary artery far end through the targeted irrigation catheter is improved.

Description

Technical Field

[0001] The invention belongs to the technical field of medical appliances, in particular to a drug delivery device for the distal end of a coronary artery via targeted infusion. Background Art

[0002] The targeted intracoronary distal drug delivery device refers to a device that delivers drugs precisely to the distal vascular area of ​​the coronary artery through a catheter during interventional treatment. Its core function is to release drugs directly and locally to the target distal coronary artery area to achieve high local drug concentrations while lowering systemic drug exposure, thereby reducing systemic side effects. Local drug delivery can quickly relieve intraoperative or postoperative coronary spasm, pain, and discomfort, and reduce the risk of postoperative restenosis and improve vascular endothelial repair by locally releasing anti-inflammatory drugs, antiproliferative drugs, etc.

[0003] A Chinese patent with publication number CN115645677A discloses a remote intracoronary drug delivery device, including a drug delivery syringe, with a drug delivery adjustment mechanism installed at the bottom of the drug delivery syringe; due to the mutual meshing of the eccentric gear and the driven wheel, the driven gear drives the guide rod to rotate along the tangential direction of the eccentric gear driven by the micro motor, and the guide rod drives the movable baffle connected to the outer wall to rotate, and the movable baffle can limit or block the outflow of the drug from the discharge port of the fixed seat; the electric heating wire heats the surface of the heat absorption tube, thereby increasing the temperature of the drug solution, preventing the drug solution temperature from being too low, causing coronary artery contraction, and slowing down or even stagnating the remote infusion rate; because the two sides of the block are sleeved inside the slide groove of the limit frame, during the rotation of the threaded handle, the block does not rotate with the threaded handle. Under the limiting action of the slide groove, the block moves up and down and is stuck on the surface of the support frame and stabilizes the support frame and the indwelling needle on the outside to prevent slipping.

[0004] The existing drug delivery device for the distal end of the coronary artery through a targeted infusion catheter is not convenient for quickly changing the drug solution for delivery to the coronary artery. When delivering the drug solution to the distal end of the coronary artery, the drug solution is injected through a syringe. If the drug solution in the syringe is insufficient, it needs to be drawn again to replenish the drug solution before delivery. When changing to a different drug solution, the drug solution also needs to be drawn again for delivery, resulting in slow drug solution replacement, cumbersome operating steps, and pauses in the work process, which reduces on-site work efficiency and response flexibility.

[0005] To this end, the present invention provides a drug delivery device for the distal end of a coronary artery via targeted infusion. Summary of the Invention

[0006] In order to remedy the deficiencies of the prior art and solve the problem of unsatisfactory efficiency in drug replacement and delivery, the present invention proposes a drug delivery device for the distal end of a coronary artery via targeted infusion into a catheter.

[0007] The technical solution adopted by the present invention to solve its technical problems is: the present invention describes a device for delivering drug to the distal end of a coronary artery through targeted infusion into a catheter, comprising a drug dispenser, a protective tube fixedly connected to the side of the drug dispenser, a pushing mechanism for pushing the drug solution provided inside the drug dispenser, a drug delivery mechanism connected to the bottom end of the drug dispenser, a secondary tube fixedly provided inside the protective tube, an electric push rod fixedly provided inside the protective tube, a compression block provided inside the secondary tube, and a telescopic end of the electric push rod fixedly connected to the center position of the compression block, a liquid extraction tube connected to the bottom end of the secondary tube, a delivery tube provided on the side of the secondary tube, and one end of the delivery tube communicated with the drug dispenser, a closing assembly provided on the delivery tube, a limiting mechanism provided on the drug dispenser, a compression groove fixedly provided inside the protective tube, and a compression mechanism provided inside the compression groove.

[0008] By adopting the above scheme, the medicine is stored in the drug dispenser, which is connected to the patient's coronary artery through the drug delivery mechanism, so that the pushing mechanism moves, and the medicine inside the drug dispenser can be pushed. The drug delivery mechanism can make the medicine flow to the patient's coronary artery for drug delivery treatment. The medicine to be delivered can be stored in the sub-tube. After the medicine inside the drug dispenser is delivered, when different medicine needs to be injected, the limiting mechanism can be controlled to move before injecting the medicine inside the drug dispenser. When the drug dispenser injects the medicine, the limiting mechanism can block and limit the pushing mechanism, and then control the closing component to no longer seal the delivery tube. The electric push rod will drive the compression block to move, and the movement of the compression block will squeeze the medicine inside the sub-tube, and the medicine will flow into the inside of the drug dispenser through the delivery tube, and the medicine will flow into the inside of the drug delivery mechanism, and the medicine will continue to be delivered through the drug delivery mechanism. In this way, working time can be reduced, work efficiency can be improved, and it is convenient to quickly change the medicine for delivery treatment.

[0009] Preferably, the closing assembly includes a No. 1 ball valve plug, a No. 1 protective box and a No. 1 drive motor, the No. 1 protective box is fixedly arranged on the delivery pipe, the No. 1 ball valve plug is rotatably arranged inside the delivery pipe, the No. 1 drive motor is fixedly arranged inside the No. 1 protective box, and the output end of the No. 1 drive motor is fixedly connected to the No. 1 ball valve plug.

[0010] By adopting the above solution, the No. 1 driving motor can drive the No. 1 ball valve plug to rotate. After the No. 1 ball valve plug rotates, it can control the opening and closing state of the delivery pipe, thereby facilitating the delivery of liquid medicine or preventing the backflow of liquid medicine.

[0011] Preferably, the liquid extraction tube is rotatably arranged inside the No. 2 ball valve plug, a No. 2 protective box is fixedly arranged on the side of the liquid extraction tube, a No. 2 driving motor is fixedly arranged inside the No. 2 protective box, and the output end of the No. 2 driving motor is fixedly connected to the No. 2 ball valve plug.

[0012] By adopting the above solution, the No. 2 driving motor will drive the No. 2 ball valve plug to rotate. When the No. 2 ball valve plug rotates, the closing state of the liquid extraction tube can be adjusted. When the electric push rod works to pull the compression block to reset, the liquid extraction tube is no longer closed, and the medicine can be extracted and stored through the liquid extraction tube.

[0013] Preferably, the pushing mechanism includes a piston, a connecting rod and a disc, the piston is arranged inside the dispenser, one end of the connecting rod is fixedly connected to the center position of the piston, and the center position of the disc is fixedly connected to the other end of the connecting rod.

[0014] By adopting the above solution, the disc can push the connecting rod to move, and the movement of the connecting rod can push the piston to move. The movement of the piston squeezes and delivers the liquid medicine inside the drug delivery device, and the drug delivery mechanism can deliver the liquid medicine for treatment.

[0015] Preferably, the drug delivery mechanism includes a connecting tube, an infusion tube, a puncture needle, a support plate and a connecting head. The support plate is fixedly arranged at the bottom end of the drug delivery device, the connecting head is fixedly arranged at the center of the support plate, and one end of the connecting head is connected to the inside of the drug delivery device. The connecting tube is sleeved on the connecting head, one end of the infusion tube is fixedly connected to the connecting tube, and the other end of the infusion tube is fixedly connected to the puncture needle. Protective sleeves are provided on the drug delivery device and the protective tube, and blocks are symmetrically connected to the drug delivery device.

[0016] By adopting the above scheme, when the piston squeezes and pushes the medicine liquid inside the drug delivery device, the puncture needle is connected to the indwelling needle connected to the coronary blood vessel. Through the cooperation of the infusion tube and the puncture needle, the medicine liquid will flow into the indwelling needle, and then the medicine liquid can enter the coronary artery for drug delivery treatment.

[0017] Preferably, a controller is fixedly installed on the side of the protective tube, and a battery assembly is fixedly installed inside the protective tube.

[0018] By adopting the above solution, the controller and the battery assembly are electrically connected to the electronic devices on the targeted intracoronary distal drug delivery device, which can control the operation of the targeted intracoronary distal drug delivery device.

[0019] Preferably, the limiting mechanism includes a receiving groove, a knob, a guide rod, a guide block, a threaded rod, a limiting block and a threaded barrel. The receiving groove is symmetrically arranged on the drug dispenser, and the receiving groove is communicated with the interior of the drug dispenser. The knob is rotatably arranged on the side of the receiving groove, the threaded rod is arranged inside the receiving groove, and one end of the threaded rod is fixedly connected to the center position of the knob. The guide rod is symmetrically arranged inside the receiving groove, the guide block is movably arranged on the guide rod, the limiting block is passed through the inside of the receiving groove, and the guide block is fixedly connected to the limiting block. The threaded barrel is fixedly arranged inside the limiting block, and the threaded rod is threadedly connected to the threaded barrel.

[0020] By adopting the above solution, turning the knob will drive the threaded rod to rotate, and the limit block will move through the threaded barrel. The cooperation of the guide rod and the guide block will make the limit block move smoothly, and then the limit block will move to the inside of the dispenser, which can block the piston and prevent the piston from moving down to seal the delivery tube.

[0021] Preferably, an annular groove is provided on the connecting head, an electric heating ring is fixedly provided inside the annular groove, and an adjusting mechanism is provided inside the connecting head.

[0022] By adopting the above solution, the heat generated by the electric heating ring can warm the connector. When the liquid medicine flows inside the connector, the temperature of the liquid medicine can be adjusted, effectively avoiding the discomfort of the patient caused by the temperature of the delivered liquid medicine being too low. The temperature of the electric heating ring is not higher than 40 degrees, and the liquid medicine can be heated to a temperature adapted to the human body, thereby improving comfort.

[0023] Preferably, the adjustment mechanism is provided with a mounting groove and an annular airbag, the mounting groove is provided inside the connector, and the annular airbag is fixedly provided inside the mounting groove.

[0024] By adopting the above solution, the connector provides installation space for the annular airbag through the installation groove. The expansion of the annular airbag volume can adjust the internal space of the connector, thereby controlling the flow rate of the drug solution, thereby improving the flexibility of the distal drug delivery device in the coronary artery through targeted infusion of the catheter.

[0025] Preferably, the compression mechanism includes an electric telescopic rod, a guide rod, a limit frame, a rubber block and an air pipe, the electric telescopic rod is fixedly arranged inside the compression groove, the rubber block is arranged inside the compression groove, and the telescopic end of the electric telescopic rod is fixedly connected to the center position of the rubber block, the limit frame is fixedly arranged inside the compression groove, the guide rod passes through the limit frame, and the bottom end of the guide rod is fixedly connected to the rubber block, one end of the air pipe is connected to the compression groove, and the other end of the air pipe is connected to the annular airbag.

[0026] By adopting the above solution, the electric telescopic rod can adjust the position of the rubber block. When the rubber block moves, it will drive the guide rod to move. The rubber block will be guided by the cooperation of the limit frame and the guide rod, so that the rubber block can move smoothly. The movement of the rubber block will compress the air inside the compression groove. The compressed air will flow into the inside of the annular airbag through the air supply pipe, and the volume of the annular airbag can be adjusted, thereby realizing the adjustment of the aperture of the inner ring of the connector for the flow of drug solution, thereby improving the flexibility of the distal drug delivery device for targeted infusion into the coronary artery of the catheter.

[0027] The beneficial effects of the present invention are as follows: 1. The drug delivery device for distal end of the coronary artery via targeted infusion catheter described in the present invention facilitates the delivery of drug solution for treatment by adopting a secondary cylinder, and the delivery tube is no longer sealed. The operation of the electric push rod will drive the compression block to move, and the movement of the compression block will squeeze the drug solution inside the secondary cylinder, and the drug solution will flow into the inside of the drug delivery device through the delivery tube, and the drug solution will flow into the inside of the drug delivery mechanism, and the drug solution will continue to be delivered through the drug delivery mechanism. In this way, working time can be reduced, working efficiency can be improved, and it is convenient to quickly replace the drug solution for delivery treatment, thereby improving the working efficiency of the drug delivery device for distal end of the coronary artery via targeted infusion catheter.

[0028] 2. The targeted intracoronary distal drug delivery device described in the present invention facilitates adjustment of the delivery aperture by the provided annular airbag, and adjusts the flow rate of the delivered drug solution through the targeted intracoronary distal drug delivery device. The electric telescopic rod can adjust the position of the rubber block. When the rubber block moves, it will drive the guide rod to move. The rubber block will be guided by the cooperation of the limit frame and the guide rod to make it move smoothly. The movement of the rubber block will compress the air inside the compression groove. The compressed air will flow into the annular airbag through the air supply pipe, and the volume of the annular airbag can be adjusted, thereby realizing the adjustment of the aperture of the inner ring of the connector for the flow of drug solution, which is convenient for controlling the flow rate of the drug solution and improving the flexibility of the targeted intracoronary distal drug delivery device.

[0029] 3. The device for delivering drug into the distal end of the coronary artery through a targeted infusion catheter described in the present invention facilitates temperature regulation of the delivered drug solution by means of an electric heating ring, thereby improving the patient's comfort. The heat generated by the electric heating ring can be controlled to heat the connector. When the drug solution flows inside the connector, the temperature of the drug solution can be regulated, effectively avoiding discomfort to the patient caused by the delivered drug solution being too low in temperature. The drug solution can be heated to a temperature adapted to the human body, thereby improving comfort. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] The present invention will be further described below with reference to the accompanying drawings.

[0031] Figure 1 This is a stereoscopic diagram of the device for delivering drug to the distal end of a coronary artery via targeted infusion into a catheter according to the present invention; Figure 2 It is a structural schematic diagram of the drug delivery device of the present invention; Figure 3 It is a structural schematic diagram of the protective tube in the present invention; Figure 4 It is a structural schematic diagram of the storage tank in the present invention; Figure 5 This invention Figure 2 A magnified schematic diagram of the structure A; Figure 6 It is a structural schematic diagram of the auxiliary cylinder in the present invention; Figure 7 It is a structural schematic diagram of the connector in the present invention; Figure 8 It is a structural schematic diagram of the compression groove in the present invention.

[0032] Figure: 1, applicator; 2, protective tube; 3, piston; 4, connecting rod; 5, disc; 7, connecting tube; 8, infusion tube; 9, puncture needle; 10, protective cover; 11, stopper; 12, controller; 13, storage slot; 14, knob; 15, guide rod; 16, guide block; 17, threaded rod; 18, limit block; 19, threaded tube; 20, battery assembly; 21, electric push rod; 22, auxiliary tube; 23, compression block; 24, extraction tube; 2 5. Delivery pipe; 26. Protection box No. 2; 27. Drive motor No. 2; 28. Ball valve plug No. 2; 29. ​​Ball valve plug No. 1; 30. Protection box No. 1; 31. Drive motor No. 1; 32. Support plate; 33. Connector; 34. Annular groove; 35. Electric heating ring; 36. Mounting groove; 37. Annular airbag; 38. Compression groove; 39. Electric telescopic rod; 40. Guide rod; 41. Limiting frame; 42. Rubber block; 43. Air pipe. DETAILED DESCRIPTION

[0033] In order to make the technical means, creative features, objectives and effects achieved by the present invention easier to understand, the present invention is further described below in conjunction with specific implementation methods.

[0034] like Figures 1 to 8 As shown, a drug delivery device for distal end of a coronary artery via targeted infusion of a catheter according to an embodiment of the present invention comprises a drug delivery device 1, a protective tube 2 is fixedly connected to the side of the drug delivery device 1, a pushing mechanism for pushing a drug solution is provided inside the drug delivery device 1, a drug delivery mechanism is connected to the bottom end of the drug delivery device 1, a secondary tube 22 is fixedly provided inside the protective tube 2, an electric push rod 21 is fixedly provided inside the protective tube 2, a compression block 23 is provided inside the secondary tube 22, and the telescopic end of the electric push rod 21 is fixedly connected to the center position of the compression block 23, a liquid extraction tube 24 is connected to the bottom end of the secondary tube 22, a delivery tube 25 is provided on the side of the secondary tube 22, and one end of the delivery tube 25 is connected to the drug delivery device 1, a closing component is provided on the delivery tube 25, a limiting mechanism is provided on the drug delivery device 1, a compression groove 38 is fixedly provided inside the protective tube 2, and a compression mechanism is provided inside the compression groove 38; When the drug delivery device at the distal end of the coronary artery of the targeted catheter is used to deliver drug to the patient's coronary artery, the drug delivery device 1 is used to store the drug solution, which is connected to the patient's coronary artery through the drug delivery mechanism. The pushing mechanism is moved to push the drug solution inside the drug delivery device 1, and the drug delivery mechanism allows the drug solution to flow to the patient's coronary artery for drug delivery. The drug solution to be delivered can be stored in the auxiliary cylinder 22. After the drug solution inside the drug delivery device 1 is delivered, when a different drug solution needs to be injected, the limit mechanism can be controlled to move before the drug solution inside the drug delivery device 1 is injected. When injecting liquid medicine, the limiting mechanism can block and limit the pushing mechanism, and then control the closing component to no longer seal the delivery tube 25. The operation of the electric push rod 21 will drive the compression block 23 to move. The movement of the compression block 23 will squeeze the liquid medicine inside the secondary cylinder 22, and the liquid medicine will flow into the inside of the drug delivery device 1 through the delivery tube 25, and the liquid medicine will flow into the inside of the drug delivery mechanism, and the liquid medicine will continue to be delivered through the drug delivery mechanism. In this way, working time can be reduced, working efficiency can be improved, and it is convenient to quickly replace the liquid medicine for delivery treatment.

[0035] Furthermore, the closing assembly includes a No. 1 ball valve plug 29, a No. 1 protection box 30, and a No. 1 drive motor 31. The No. 1 protection box 30 is fixedly mounted on the delivery pipe 25. The No. 1 ball valve plug 29 is rotatably mounted inside the delivery pipe 25. The No. 1 drive motor 31 is fixedly mounted inside the No. 1 protection box 30, and the output end of the No. 1 drive motor 31 is fixedly connected to the No. 1 ball valve plug 29. When the closing component works to control the opening and closing of the delivery pipe 25, the No. 1 drive motor 31 drives the No. 1 ball valve plug 29 to rotate. After the No. 1 ball valve plug 29 rotates, it can control the opening and closing state of the delivery pipe 25, thereby facilitating the delivery of the liquid medicine or preventing the liquid medicine from flowing back.

[0036] Furthermore, a second ball valve plug 28 is rotatably mounted inside the liquid extraction tube 24, a second protection box 26 is fixedly mounted on the side of the liquid extraction tube 24, a second drive motor 27 is fixedly mounted inside the second protection box 26, and an output end of the second drive motor 27 is fixedly connected to the second ball valve plug 28; When the No. 2 driving motor 27 is working, it will drive the No. 2 spherical valve plug 28 to rotate. When the No. 2 spherical valve plug 28 rotates, the closing state of the liquid extraction tube 24 can be adjusted. When the electric push rod 21 works to pull the compression block 23 to reset, the liquid extraction tube 24 is no longer closed, and the liquid medicine can be extracted and stored through the liquid extraction tube 24.

[0037] Furthermore, the pushing mechanism includes a piston 3, a connecting rod 4 and a disc 5. The piston 3 is arranged inside the applicator 1. One end of the connecting rod 4 is fixedly connected to the center of the piston 3. The center of the disc 5 is fixedly connected to the other end of the connecting rod 4. When the drug delivery device 1 injects and delivers the drug solution, the disc 5 can push the connecting rod 4 to move, and the connecting rod 4 can push the piston 3 to move. The movement of the piston 3 squeezes and delivers the drug solution inside the drug delivery device 1, and the drug solution can be delivered for treatment through the drug delivery mechanism.

[0038] Furthermore, the drug delivery mechanism includes a connecting tube 7, an infusion tube 8, a puncture needle 9, a support disk 32 and a connector 33. The support disk 32 is fixedly arranged at the bottom end of the drug delivery device 1, and the connector 33 is fixedly arranged at the center of the support disk 32. One end of the connector 33 is connected to the inside of the drug delivery device 1. The connecting tube 7 is sleeved on the connector 33. One end of the infusion tube 8 is fixedly connected to the connecting tube 7, and the other end of the infusion tube 8 is fixedly connected to the puncture needle 9. A protective sleeve 10 is provided on the drug delivery device 1 and the protective tube 2, and a stopper 11 is symmetrically connected to the drug delivery device 1; The connecting tube 7 is connected to the connecting head 33. When the piston 3 squeezes and pushes the medicine inside the drug delivery device 1, the puncture needle 9 is connected to the indwelling needle connected to the coronary blood vessel. Through the cooperation of the infusion tube 8 and the puncture needle 9, the medicine will flow into the indwelling needle, and then the medicine can enter the coronary artery for drug delivery treatment.

[0039] Furthermore, a controller 12 is fixedly installed on the side of the protective tube 2, and a battery assembly 20 is fixedly installed inside the protective tube 2; The controller 12 and the battery assembly 20 are both electrically connected to the electronic devices on the device for delivering drug to the distal end of the coronary artery through targeted infusion catheterization, and can control the operation of the device for delivering drug to the distal end of the coronary artery through targeted infusion catheterization.

[0040] Furthermore, the limiting mechanism includes a receiving groove 13, a knob 14, a guide rod 15, a guide block 16, a threaded rod 17, a limiting block 18 and a threaded barrel 19. The receiving groove 13 is symmetrically arranged on the applicator 1, and the receiving groove 13 is communicated with the interior of the applicator 1. The knob 14 is rotatably arranged on the side of the receiving groove 13, the threaded rod 17 is arranged inside the receiving groove 13, and one end of the threaded rod 17 is fixedly connected to the center position of the knob 14. The guide rod 15 is symmetrically arranged inside the receiving groove 13, the guide block 16 is movably arranged on the guide rod 15, the limiting block 18 is passed through the inside of the receiving groove 13, and the guide block 16 is fixedly connected to the limiting block 18. The threaded barrel 19 is fixedly arranged inside the limiting block 18, and the threaded rod 17 is threadedly connected to the threaded barrel 19. The limiting mechanism limits the position of the piston 3 to prevent the piston 3 from blocking the end of the delivery tube 25 and causing sealing. When the knob 14 is turned, the threaded rod 17 will be driven to rotate, and the limit block 18 will be moved through the threaded cylinder 19. The guide rod 15 and the guide block 16 cooperate to make the limit block 18 move smoothly, and then the limit block 18 is moved to the inside of the drug dispenser 1, which can block the piston 3 and prevent the piston 3 from moving down to seal the delivery tube 25. A sealing ring is provided between the receiving groove 13 and the limit block 18, which can effectively prevent the drug solution from entering the inside of the receiving groove 13.

[0041] Furthermore, an annular groove 34 is provided on the connector 33, an electric heating ring 35 is fixedly provided inside the annular groove 34, and an adjustment mechanism is provided inside the connector 33; The heat generated by controlling the operation of the electric heating ring 35 can heat the connecting head 33. When the liquid medicine flows inside the connecting head 33, the temperature of the liquid medicine can be adjusted, effectively avoiding the discomfort of the patient caused by the temperature of the delivered liquid medicine being too low. The temperature of the electric heating ring 35 is not higher than 40 degrees, and the liquid medicine can be heated to a temperature adapted to the human body, thereby improving comfort.

[0042] Furthermore, the adjustment mechanism is provided with a mounting groove 36 and an annular airbag 37 . The mounting groove 36 is provided inside the connector 33 , and the annular airbag 37 is fixedly provided inside the mounting groove 36 . The connector 33 provides installation space for the annular airbag 37 through the installation groove 36. The volume expansion of the annular airbag 37 can adjust the internal space of the connector 33, thereby controlling the flow rate of the drug solution, thereby improving the flexibility of the distal drug delivery device in the coronary artery through targeted infusion of the catheter.

[0043] Furthermore, the compression mechanism includes an electric telescopic rod 39, a guide rod 40, a limiting frame 41, a rubber block 42 and an air pipe 43. The electric telescopic rod 39 is fixedly arranged inside the compression groove 38, the rubber block 42 is arranged inside the compression groove 38, and the telescopic end of the electric telescopic rod 39 is fixedly connected to the center position of the rubber block 42. The limiting frame 41 is fixedly arranged inside the compression groove 38. The guide rod 40 passes through the limiting frame 41, and the bottom end of the guide rod 40 is fixedly connected to the rubber block 42. One end of the air pipe 43 is connected to the compression groove 38, and the other end of the air pipe 43 is connected to the annular airbag 37. The electric telescopic rod 39 can adjust the position of the rubber block 42. When the rubber block 42 moves, it will drive the guide rod 40 to move. The rubber block 42 will be guided by the cooperation of the limit frame 41 and the guide rod 40, so that the rubber block 42 can move smoothly. The movement of the rubber block 42 will compress the air inside the compression groove 38. The compressed air will flow into the annular airbag 37 through the air supply pipe 43, and the volume of the annular airbag 37 can be adjusted, thereby realizing the adjustment of the aperture of the inner ring of the connector 33 for the flow of liquid medicine, thereby improving the flexibility of the distal drug delivery device for targeted infusion into the coronary artery of the catheter.

[0044] Working principle: First, when using the drug delivery device at the distal end of the coronary artery of the targeted catheter for drug delivery treatment to the patient's coronary artery, the drug delivery device 1 is used to store the drug solution, which is connected to the patient's coronary artery through the drug delivery mechanism. The connecting rod 4 can be pushed to move by the disc 5. When the connecting rod 4 moves, the piston 3 can be pushed to move. The movement of the piston 3 squeezes and delivers the drug solution inside the drug delivery device 1, so that the puncture needle 9 is connected to the indwelling needle connected to the coronary blood vessel. The infusion tube 8 and the puncture needle 9 cooperate to make the drug solution flow into the indwelling needle, and then the drug solution can enter the coronary artery for drug delivery treatment. The drug solution to be delivered can be stored through the auxiliary cylinder 22. After the drug solution inside the drug delivery device 1 is delivered, it is necessary to When injecting different liquid medicines, before injecting the liquid medicine inside the drug delivery device 1, the movement of the limit mechanism can be controlled, and rotating the knob 14 will drive the threaded rod 17 to rotate, and the threaded barrel 19 will move the limit block 18, and the cooperation of the guide rod 15 and the guide block 16 will make the limit block 18 move smoothly, and then the limit block 18 moves to the inside of the drug delivery device 1, which can block the piston 3 to prevent the piston 3 from moving down and sealing the delivery tube 25. The No. 1 driving motor 31 can drive the No. 1 ball valve plug 29 to rotate. After the No. 1 ball valve plug 29 rotates, the opening and closing state of the delivery tube 25 can be controlled, thereby facilitating the delivery of liquid medicine, or preventing the liquid medicine from flowing back, and no longer sealing the delivery tube 25. The electric push The operation of the rod 21 will drive the compression block 23 to move, and the movement of the compression block 23 will squeeze the liquid medicine inside the sub-tube 22, and the liquid medicine will flow into the inside of the drug delivery device 1 through the delivery tube 25, and the liquid medicine will flow into the inside of the drug delivery mechanism, and the drug delivery mechanism will continue to deliver the liquid medicine. In this way, the working time can be reduced, the working efficiency can be improved, and it is convenient to quickly change the liquid medicine for delivery treatment. The heat generated by controlling the operation of the electric heating ring 35 can heat the connector 33. When the liquid medicine flows inside the connector 33, the temperature of the liquid medicine can be adjusted to effectively avoid the temperature of the delivered liquid medicine being too low and causing discomfort to the patient. The temperature of the electric heating ring 35 is not higher than 40 degrees, and the liquid medicine can be heated to The temperature adapted to the human body improves comfort. The electric telescopic rod 39 can adjust the position of the rubber block 42. When the rubber block 42 moves, it will drive the guide rod 40 to move. The rubber block 42 will be guided by the cooperation of the limit frame 41 and the guide rod 40, so that the rubber block 42 moves smoothly. The movement of the rubber block 42 will compress the air inside the compression groove 38. The compressed air will flow into the annular airbag 37 through the air supply pipe 43, and the volume of the annular airbag 37 can be adjusted, thereby realizing the adjustment of the aperture of the inner ring of the connector 33 for the flow of the drug solution, which is convenient for controlling the flow rate of the drug solution and improving the flexibility of the distal drug delivery device for targeted coronary artery catheterization.

[0045] The basic principles, main features, and advantages of the present invention are shown and described above. Those skilled in the art should understand that the present invention is not limited to the foregoing embodiments. The foregoing embodiments and descriptions are merely illustrative of the principles of the present invention. Various changes and modifications may be made to the present invention without departing from the spirit and scope of the present invention. Such changes and modifications are intended to fall within the scope of the present invention. The scope of protection claimed in the present invention is defined by the appended claims and their equivalents.

Claims

1. A drug delivery device for distal coronary artery delivery via targeted infusion catheter, characterized in that: The invention comprises a drug dispenser (1), wherein a protective tube (2) is fixedly connected to the side of the drug dispenser (1), a pushing mechanism for pushing a liquid medicine is provided inside the drug dispenser (1), a drug dispensing mechanism is connected to the bottom end of the drug dispenser (1), a secondary tube (22) is fixedly provided inside the protective tube (2), an electric push rod (21) is fixedly provided inside the protective tube (2), a compression block (23) is provided inside the secondary tube (22), and the telescopic end of the electric push rod (21) is fixedly connected to the center position of the compression block (23), a liquid extraction tube (24) is connected to the bottom end of the secondary tube (22), a delivery tube (25) is provided on the side of the secondary tube (22), and one end of the delivery tube (25) is connected to the drug dispenser (1), a closing component is provided on the delivery tube (25), a limiting mechanism is provided on the drug dispenser (1), a compression groove (38) is fixedly provided inside the protective tube (2), and a compression mechanism is provided inside the compression groove (38).

2. The device for delivering drug to the distal end of a coronary artery via targeted infusion catheter according to claim 1, characterized in that: The closing assembly comprises a No. 1 spherical valve plug (29), a No. 1 protection box (30) and a No. 1 driving motor (31), wherein the No. 1 protection box (30) is fixedly arranged on the delivery pipe (25), the No. 1 spherical valve plug (29) is rotatably arranged inside the delivery pipe (25), the No. 1 driving motor (31) is fixedly arranged inside the No. 1 protection box (30), and the output end of the No. 1 driving motor (31) is fixedly connected to the No. 1 spherical valve plug (29).

3. The device for delivering drug to the distal end of a coronary artery via targeted infusion catheter according to claim 2, characterized in that: The liquid extraction pipe (24) is rotatably mounted inside a No. 2 ball valve plug (28), a No. 2 protection box (26) is fixedly mounted on the side of the liquid extraction pipe (24), a No. 2 drive motor (27) is fixedly mounted inside the No. 2 protection box (26), and an output end of the No. 2 drive motor (27) is fixedly connected to the No. 2 ball valve plug (28).

4. The device for delivering drug to the distal end of a coronary artery via targeted infusion catheter according to claim 3, characterized in that: The pushing mechanism comprises a piston (3), a connecting rod (4) and a disc (5); the piston (3) is arranged inside the dispenser (1); one end of the connecting rod (4) is fixedly connected to the center of the piston (3); and the center of the disc (5) is fixedly connected to the other end of the connecting rod (4).

5. The device for delivering drug to the distal end of a coronary artery via targeted infusion catheter according to claim 4, characterized in that: The drug delivery mechanism comprises a connecting tube (7), an infusion tube (8), a puncture needle (9), a support plate (32) and a connector (33), wherein the support plate (32) is fixedly arranged at the bottom end of the drug delivery device (1), the connector (33) is fixedly arranged at the center of the support plate (32), and one end of the connector (33) is connected to the inside of the drug delivery device (1), the connecting tube (7) is sleeved on the connector (33), one end of the infusion tube (8) is fixedly connected to the connecting tube (7), and the other end of the infusion tube (8) is fixedly connected to the puncture needle (9), the drug delivery device (1) and the protective tube (2) are both provided with a protective sleeve (10), and the drug delivery device (1) is symmetrically connected with a stopper (11).

6. The device for delivering drug to the distal end of a coronary artery via targeted infusion catheter according to claim 5, characterized in that: A controller (12) is fixedly provided on the side of the protective tube (2), and a battery assembly (20) is fixedly provided inside the protective tube (2).

7. The device for delivering drug to the distal end of a coronary artery via targeted infusion catheter according to claim 6, characterized in that: The limiting mechanism includes a receiving groove (13), a knob (14), a guide rod (15), a guide block (16), a threaded rod (17), a limiting block (18) and a threaded barrel (19), wherein the receiving groove (13) is symmetrically arranged on the drug dispenser (1), and the receiving groove (13) is connected to the inside of the drug dispenser (1), the knob (14) is rotatably arranged on the side of the receiving groove (13), the threaded rod (17) is arranged inside the receiving groove (13), and the threaded rod One end of (17) is fixedly connected to the center position of the knob (14), the guide rod (15) is symmetrically arranged inside the receiving groove (13), the guide block (16) is movably arranged on the guide rod (15), the limit block (18) is passed through the receiving groove (13), and the guide block (16) is fixedly connected to the limit block (18), the threaded barrel (19) is fixedly arranged inside the limit block (18), and the threaded rod (17) is threadedly connected to the threaded barrel (19).

8. The device for delivering drug to the distal end of a coronary artery via targeted infusion catheter according to claim 7, characterized in that: An annular groove (34) is provided on the connecting head (33), an electric heating ring (35) is fixedly provided inside the annular groove (34), and an adjusting mechanism is provided inside the connecting head (33).

9. The device for delivering drug to the distal end of a coronary artery via targeted infusion catheter according to claim 8, characterized in that: The adjustment mechanism is provided with a mounting groove (36) and an annular airbag (37), the mounting groove (36) is provided inside the connector (33), and the annular airbag (37) is fixedly provided inside the mounting groove (36).

10. The drug delivery device for distal end of a coronary artery via targeted infusion catheter according to claim 9, characterized in that: The compression mechanism comprises an electric telescopic rod (39), a guide rod (40), a limiting frame (41), a rubber block (42) and an air supply pipe (43). The electric telescopic rod (39) is fixedly arranged inside the compression groove (38), the rubber block (42) is arranged inside the compression groove (38), and the telescopic end of the electric telescopic rod (39) is fixedly connected to the center position of the rubber block (42). The limiting frame (41) is fixedly arranged inside the compression groove (38), the guide rod (40) passes through the limiting frame (41), and the bottom end of the guide rod (40) is fixedly connected to the rubber block (42). One end of the air supply pipe (43) is connected to the compression groove (38), and the other end of the air supply pipe (43) is connected to the annular airbag (37).

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