Pig skin cream medicine for treating skin itch and preparation method thereof

Abstract

The invention relates to a pig skin cream medicine for treating skin itch and a preparation method thereof, the pig skin cream medicine is used for treating skin itch, and the medicine comprises 80-120g of fresh pigskin, 25-30g of white honey, 40-50g of polished round-grained rice powder, 12-15g of angelica sinensis, 8-10g of fructus cnidii, 5-10g of borneol, 250g of lard and 60g of disordered hair or chicken. The preparation method comprises the following steps: 1, decocting Chinese angelica and common cnidium fruit into traditional Chinese medicine soup; 2, frying with pig paste: mixing lard oil and hair into paste, decocting with soft fire, and removing slag to prepare the pig paste; 3, decoction of pig skin soup: adding the traditional Chinese medicine soup into fresh pig skin; 4, polished round-grained rice powder is added into the pig skin decoction for decoction, whitish honey is added for stirring, pig cream is added for boiling, powdered borneol is added for stirring, cooling is performed, and the pig skin cream is obtained.The cream is externally applied to the skin itch position, and the effects of nourishing yin, moistening dryness, dispelling wind, relieving itching and moistening skin are jointly achieved. The medicine is externally applied locally, so that the efficacy of the medicine can directly reach the affected area, the dry state of the skin is effectively improved, the skin barrier can be protected by moistening the skin, preventing epidermis moisture loss and increasing cuticle moisture, then the skin itch is relieved, and the effects of nourishing yin, moistening dryness, dispelling wind, relieving itching and moistening the skin are achieved.

Description

Technical Field

[0001] The invention relates to a traditional Chinese medicine formula and a preparation method, in particular to a pig skin ointment medicine for treating skin itching and a preparation method thereof. Technical Background

[0002] Itching is one of the most common skin symptoms and can be caused by a variety of factors, including high blood sugar, liver and gallbladder diseases, and skin diseases such as eczema, urticaria, and psoriasis. Dry skin or allergic reactions can also cause itching.

[0003] Itching can tempt patients to temporarily relieve itching by pinching, scratching, or rubbing their skin with objects. However, this vicious cycle of itching, scratching, and itching can exacerbate the deterioration of skin barrier function and the severity of itching. Furthermore, nocturnal itching can reduce sleep time, leading to sleep disorders, fatigue, anxiety, depression, and even self-harm and suicidal thoughts, severely impacting patients' quality of life and mental health.

[0004] While modern medicine treats pruritus based on the underlying cause, Traditional Chinese Medicine (TCM) employs a syndrome-based approach, achieving remarkable results. In addition to conventional treatments such as hypoglycemic measures, topical TCM therapies often moisturize the skin, prevent epidermal water loss, and increase stratum corneum moisture, thereby protecting the skin barrier and alleviating itching. Traditional Chinese medicine formulas, through their multi-targeted regulation (on glucose and lipid metabolism, neuroinflammation, and microcirculation), exhibit holistic regulatory properties in skin lesions. Recent clinical practice has demonstrated that stage-specific syndrome differentiation of pruritus (such as damp-heat accumulation in the skin and yin deficiency and wind-dryness) can improve barrier function by regulating transepidermal water loss (TEWL) and stratum corneum water content (SCH). Western medications primarily focus on topical applications, supplemented by intramuscular and oral vitamin therapy.

[0005] Traditional Chinese medicine believes that this disease belongs to the category of "wind pruritus". Its etiology and pathogenesis are mainly due to lack of nourishment to the skin or blood deficiency and wind dryness. Qi and Yin deficiency with blood stasis is one of its main syndromes. Therefore, treatment and care should focus on invigorating Qi and nourishing Yin, and removing blood stasis. Summary of the Invention

[0006] The invention adds cnidium monnieri and angelica to the original recipe of the traditional "Treatise on Febrile Diseases", which has the effects of sterilization, moisturizing and relieving itching. When combined with the pig paste decoction recipe in "Golden Chamber", the effects of both are better.

[0007] The traditional Chinese medicine formula adopted by the present invention to achieve the purpose of the invention is: the pig skin paste medicine is prepared from the following traditional Chinese medicines by weight: 80-120g of fresh pig skin, 25-30g of white honey, 40-50g of polished rice flour, 12-15g of angelica, 8-10g of cnidium monnieri, 5-10g of borneol, 250-300g of lard, and 45-60g of tangerine peel or chicken.

[0008] The preparation method adopted by the present invention to achieve the purpose of the invention is: The preparation method comprises the following steps: Step 1. Take 12-15g of Chinese Angelica and 8-10g of Cnidium monnieri, add 1000ml of water each time, and boil the medicine until the concentration reaches 200ml per dose. Boil for 3 doses to obtain a total of 600ml of Chinese medicine decoction. Step 2. Decoction of lard paste: Soak loose hair in 0.9% saline and sterilize in boiling water. Combine 250g of lard, 60g of loose hair, and the paste, and simmer over medium-low heat for 2-2.5 hours. Remove the residue and make the lard paste. Step 3. Boil pig skin soup: 50g fresh pig skin, add 200ml of the Chinese medicine soup in step 1 each time, boil for 1.5h each time, boil for 3 doses, remove the residue and combine the pig skin soup decoction, continue to boil until concentrated to 400ml; Step 4. Add 20g of fried and sieved rice flour to the pig skin soup decoction in step 3 and continue to boil for half an hour. After it becomes a paste, add 40ml of white honey and stir evenly. Add the pig paste in step 2 and boil. Add 5g of powdered borneol and stir evenly to obtain pig skin soup. Cool to obtain pig skin paste.

[0009] The present invention has the beneficial effects of: applying the ointment to itchy skin areas, it nourishes yin and moisturizes dryness, eliminates wind and relieves itching, and moisturizes the skin. Topical application of the drug allows the drug to reach the affected area directly, effectively improving dry skin. By moisturizing the skin, preventing epidermal water loss, and increasing stratum corneum moisture, it protects the skin barrier, thereby relieving itching and achieving the effects of nourishing yin and moisturizing dryness, eliminating wind and relieving itching, and moisturizing the skin. DETAILED DESCRIPTION

[0010] A pig skin plaster for treating skin itching is prepared from the following Chinese medicinal materials by weight: 80-120g of fresh pig skin, 25-30g of white honey, 40-50g of polished rice flour, 12-15g of angelica sinensis, 8-10g of cnidium monnieri, 5-10g of borneol, 250-300g of lard, and 45-60g of linalool or chicken.

[0011] In the preferred embodiment of the present invention, the pig skin paste medicine is made from the following Chinese medicines by weight: 100g fresh pig skin, 25g white honey, 45g polished rice flour, 12g angelica, 8g cnidium monnieri, 5g borneol, 250g lard, and 60g of luanfa or chicken.

[0012] The main drug is fresh pig skin. Nature and flavor: sweet and cool, entering the lung, kidney and spleen meridians.

[0013] Total polyphenols>450mg / kg, scavenging efficiency of DPPH free radicals reaches 89%, antibacterial spectrum: against Staphylococcus aureus.

[0014] Adjuvant: Angelica sinensis. Nature and flavor: sweet, pungent and warm, enters the liver, heart and spleen meridians Traditional efficacy: Nourishes kidney yin and nourishes the skin (Compendium of Materia Medica: Pig skin moisturizes and relieves fever) Nourishing Yin, moistening dryness and relieving restlessness (treating Shaoyin diarrhea and sore throat in Treatise on Febrile Diseases) Modern pharmacology: Collagen peptides can activate TLR2 receptors to promote barrier repair and increase the expression of hyaluronic acid synthase (HAS2) by 2.8 times.

[0015] Assistant drug: white honey (sophora flower honey). Nature and flavor: sweet and mild, enters the lung, spleen, and large intestine meridians Core function: moisturizing, detoxifying, regulating epidermal flora (according to Benjing, it mainly treats evil spirits in the heart and abdomen) Promotes wound repair (combined wogonin content > 0.6%) Angelica sinensis: Polysaccharides promote angiogenesis. Ligustilide inhibits TRPV1 itch receptor.

[0016] Cnidium monnieri: Nature and flavor: Pungent, pungent and warm, enters the kidney meridian. Osthole has antihistamine activity.

[0017] Japonica rice: Nature and flavor: sweet, mild and neutral, enters the spleen and stomach meridians.

[0018] Functional analysis: Amylose forms a protective gel layer (swelling degree ≥ 300%) Oryzanol regulates sebaceous gland function (5α-reductase inhibition rate 62%).

[0019] Efficacy: Regulates the epidermal pH to 5.5-6.0 and enhances the barrier function Lard: In this formula, it primarily serves as a base, emollient, lipid supplement, carrier, and transdermal enhancer. Its core functions are to physically lock in moisture, replenish skin lipids to aid in barrier repair (combined with pigskin and glutinous rice), and act as an excipient to carry other drug ingredients and promote their transdermal absorption.

[0020] Medicinal Guide: Traditionally believed to guide the effects of various herbs downward (relieves sore throat) and into the kidneys, it also promotes blood circulation, removes stasis, and eliminates heat (echoing the pungent, pungent, warming, and dispersing properties of Cnidium monnieri). Decoction may provide a mixture of amino acids and trace elements, nourishing and regulating skin metabolism, and potentially affecting the viscosity of ointments. (If replaced with egg yolk, its effects shift to stronger yin-nourishing and moistening properties, providing bioactive compounds like lecithin, and emulsifying to improve the ointment's texture.)

[0021] The preparation method of a pig skin ointment medicine for treating skin itching of the present invention is: The preparation method comprises the following steps: Step 1. Take 12-15g of Chinese Angelica and 8-10g of Cnidium monnieri, add 1000ml of water each time, and boil the medicine until the concentration reaches 200ml per dose. Boil for 3 doses to obtain a total of 600ml of Chinese medicine decoction. Step 2. Decoction of lard paste: Soak loose hair in 0.9% saline and sterilize in boiling water. Combine 250g of lard, 60g of loose hair, and the paste, and simmer over medium-low heat for 2-2.5 hours. Remove the residue and make the lard paste. Step 3. Boil pig skin soup: 50g fresh pig skin, add 200ml of the Chinese medicine soup in step 1 each time, boil for 1.5h each time, boil for 3 doses, remove the residue and combine the pig skin soup decoction, continue to boil until concentrated to 400ml; Step 4. Add 20g of fried and sieved rice flour to the pig skin soup decoction in step 3 and continue to boil for half an hour. After it becomes a paste, add 40ml of white honey and stir evenly. Add the pig paste in step 2 and boil. Add 5g of powdered borneol and stir evenly to obtain pig skin soup. Cool to obtain pig skin paste.

[0022] The Chinese medicine external-use ointment of the present invention is formulated under the guidance of traditional Chinese medicine theory, and then concentrated into a paste through decoction, allowing it to fully act on the surface of the skin and mucous membranes and directly reach the affected area. It has the characteristics of high transmittance, high absorption rate, and controllable dosage. This study uses the original recipe of Zhufu Decoction from the traditional "Treatise on Febrile Diseases" and adds two herbs, Cnidium monnieri and Angelica sinensis, which have antibacterial, moisturizing and antipruritic effects. It is combined with the Zhugao decoction recipe from the "Golden Chamber Synopsis". The ancient recipe is concentrated into an ointment through a preparation process. The therapeutic effect on pruritus is observed, providing technical and data support for clinical application and promotion, and also enriching the content and coverage of Chinese medicine ointments for external application to treat pruritus.

[0023]

Claims

1. A pig skin ointment medicine for treating skin itching, characterized in that: The pig skin paste is prepared from the following Chinese medicines by weight: 80-120g of fresh pig skin, 25-30g of white honey, 40-50g of polished rice flour, 12-15g of angelica sinensis, 8-10g of cnidium monnieri, 5-10g of borneol, 250-300g of lard, and 45-60g of linalool or chicken.

2. A pig skin ointment medicine for treating skin itching according to claim 1, characterized in that: The pig skin paste is prepared from the following Chinese medicines by weight: 100g fresh pig skin, 25g white honey, 45g polished rice flour, 12g angelica, 8g cnidium monnieri, 5g borneol, 250g lard, and 60g rouge or chicken.

3. A method for preparing a pig skin ointment medicine for treating skin itching according to claim 1 or 2, characterized in that: The preparation method comprises the following steps: Step 1. Take 12-15g of Chinese Angelica and 8-10g of Cnidium monnieri, add 1000ml of water each time, and boil the medicine until the concentration reaches 200ml per dose. Boil for 3 doses to obtain a total of 600ml of Chinese medicine decoction. Step 2. Decoction of lard: Soak loose hair in 0.9% saline and sterilize in boiling water. Combine 250g of lard, 60g of loose hair, and the paste. Boil over medium-low heat for 2-2.5 hours. Remove the residue and make the lard paste. Step 3. Boil pig skin soup: 50g fresh pig skin, add 200ml of the Chinese medicine soup in step 1 each time, boil for 1.5h each time, boil for 3 doses, remove the residue and combine the pig skin soup decoction, continue to boil until concentrated to 400ml; Step 4. Add 20g of fried and sieved rice flour to the pig skin soup decoction in step 3 and continue to boil for half an hour. After it becomes a paste, add 40ml of white honey and stir evenly. Add the pig paste in step 2 and boil. Add 5g of powdered borneol and stir evenly to obtain pig skin soup. Cool to obtain pig skin paste.

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