Trowel face layering repairing method

Abstract

The invention discloses a trowel face layered repair method, which comprises the following steps of: acquiring detailed structure, filler distribution and tissue activity information of each layer (epidermal layer, corium layer, subcutaneous fat layer and fascia layer) of the face by utilizing a multi-mode image fusion technology and combining high-resolution ultrasonic imaging and near infrared spectrum analysis; constructing a three-dimensional digital face model; according to a model analysis result, customizing an exclusive repair scheme of each level, the scheme comprising a repair agent with a level specific activation mechanism and a matched physical intervention means; according to the sequence of repairing from the epidermal layer to the deep layer in sequence, repairing parameters are monitored and adjusted based on real-time feedback after each layer is repaired, and the repairing interval of the adjacent layers is determined according to the healing process of the tissue of the previous layer. Therefore, by means of the hierarchical specific repairing agent, physical intervention and a dynamic adjustment mechanism, targeted repairing of all levels is achieved, and the accuracy and durability of the repairing effect are improved.

Description

Technical Field

[0001] The present invention relates to the technical field of mending facial wrinkles, and in particular to a multi-layered mending method for mending facial wrinkles. Background Art

[0002] In the field of medical aesthetics, the main techniques currently used to repair a chubby face include lytic enzyme injection, radiofrequency skin tightening, gold microneedles, Thermage, ultrasonic scalpel, face lift, and facial liposuction. Lytic enzyme injection can quickly dissolve excess fillers such as hyaluronic acid or collagen. Radiofrequency skin tightening, gold microneedles, Thermage, and ultrasonic scalpel can stimulate collagen contraction and regeneration to increase skin firmness. Face lifts use surgical procedures to lift and fix facial tissues. Facial liposuction uses negative pressure or ultrasound to suck out excess fat from the face. These techniques can improve the chubby face to a certain extent.

[0003] However, the existing technology has obvious defects, namely, it is difficult to achieve precise layered repair of the chubby face. The facial skin and subcutaneous tissue are divided into multiple layers. The causes of the chubby face are diverse, and different layers are affected differently. For example, the chubby face caused by factors such as excessive filling, improper filling layers, and migration of fillers manifests differently in different layers. However, the existing technical means often act on the face in a holistic and single manner, and cannot perform targeted repairs on specific problems at different layers, resulting in poor repair effects and difficulty in restoring the face to its natural state. Summary of the Invention

[0004] The present invention aims to solve one of the technical problems in the related art at least to a certain extent.

[0005] To this end, the purpose of the present invention is to propose a method for layered repair of crepey face, which accurately diagnoses the conditions of various facial layers through multimodal image fusion technology, customizes a layered repair plan containing layer-specific activation repair agents and supporting physical interventions, and combines real-time monitoring and dynamic adjustment of the crepey face layered repair technology plan; it solves the problem in the background technology that the existing technology is difficult to achieve accurate crepey face layered repair, realizes targeted repair from the epidermis to the fascia layer, and improves the accuracy and effectiveness of the repair effect.

[0006] To achieve the above objectives, the present invention proposes a layered repair method for a shriveled face, comprising the following steps: utilizing multimodal image fusion technology, combined with high-resolution ultrasound imaging and near-infrared spectroscopy analysis, to obtain detailed structural, filler distribution, and tissue activity information of each facial layer (epidermis, dermis, subcutaneous fat layer, and fascia layer), and constructing a three-dimensional digital facial model; based on the model analysis results, customizing a dedicated repair plan for each layer, which includes a repair agent with a layer-specific activation mechanism and supporting physical intervention measures; starting from the epidermis and proceeding to the deeper layers, the repair parameters are adjusted after each layer is repaired based on real-time feedback monitoring, and the repair interval between adjacent layers is determined according to the healing process of the previous layer of tissue.

[0007] The present invention proposes a layered repair method for smudged facial skin. Using multimodal image fusion, the method precisely locates fillers and structural abnormalities at each facial layer. A customized regimen containing layer-specific activating repair agents and accompanying physical interventions is then applied sequentially from the epidermis to the fascia. This approach, combined with real-time monitoring and dynamic adjustment, determines repair intervals based on tissue healing markers to achieve precise layered repair. This method addresses the limitations of existing technologies in achieving precise layered repair. By utilizing layer-specific repair agents, coordinated physical intervention, and a dynamic adjustment mechanism, it achieves targeted repair at each layer, improving the accuracy and durability of the repair effect.

[0008] Specifically, in the multimodal image fusion technology, the resolution of high-resolution ultrasound imaging reaches 0.05mm, which can clearly distinguish the details of tissue structure at each level; near-infrared spectral analysis can identify the characteristic spectra of various fillers such as hyaluronic acid, collagen, autologous fat, and accurately locate the distribution of fillers at different levels. The recognition accuracy rate is higher than 95%. Through the fusion of the two, the thickness of each level, the volume and position information of the filler can be accurately presented in the three-dimensional digital facial model, providing a basis for customized repair plans.

[0009] Specifically, the repair agent with a layer-specific activation mechanism uses a light-activated repair agent in the epidermal layer, which contains epidermal growth factor and antioxidants encapsulated in photosensitive liposomes. Under light of a specific wavelength (400-450nm), the liposomes rupture and release active ingredients, promoting epidermal cell proliferation and barrier repair; the dermis uses a pH-responsive repair agent, which contains hyaluronidase and collagen synthesis promoter loaded with pH-sensitive polymer microspheres. Under the pH value of the dermis (about 7.0-7.4), the microspheres degrade and release drugs, decompose excess fillers and stimulate collagen regeneration; the subcutaneous fat layer uses a temperature-sensitive repair agent, which encapsulates lipolysis enzymes with thermosensitive hydrogels. When the temperature reaches 37°C, the hydrogel swells and releases the enzyme, accurately decomposing excess fat cells; the fascia layer uses a mechanical-responsive repair agent, which is composed of fascia repair peptides carried by stretchable nanofiber carriers. When the fascia is stretched, the nanofiber structure changes and releases peptides, promoting fascia elasticity recovery.

[0010] Specifically, in the photoactivated repair agent of the epidermal layer, the particle size of the photosensitive liposome is 100-200nm, the encapsulation rate of epidermal growth factor is not less than 80%, and the antioxidant is ferulic acid with a mass fraction of 0.5% to 1.5%; in the pH-responsive repair agent of the dermis layer, the particle size of the pH-sensitive polymer microspheres is 50-100μm, the hyaluronidase loading amount is 5% to 10% of the microsphere mass, and the collagen synthesis promoter is proline with a mass fraction of 0.2% to 0.8%; in the temperature-sensitive repair agent of the subcutaneous fat layer, the lower critical solution temperature of the thermosensitive hydrogel is 37°C, the specific activity of the lipolytic enzyme is 500-1000U / mg, and the encapsulation rate is not less than 70%; in the mechanical-responsive repair agent of the fascia layer, the diameter of the stretchable nanofibers is 50-100nm, and the loading amount of the fascia repair peptide is 10-50μg per mg of nanofibers.

[0011] Specifically, the supporting physical intervention measures are designed in coordination with the needs of layer repair: the epidermis uses microcurrent introduction technology, combined with nano-microneedles to open the stratum corneum channel, with a microcurrent intensity of 0.1-0.5 mA to promote the penetration of light-activated repair agents, and at the same time uses low-energy red light irradiation (wavelength 630-660nm, energy density 5-10J / cm 2 ) to enhance the activity of epidermal cells; the dermis layer uses focused ultrasound (frequency 5-8MHz) to promote the uniform diffusion of pH-responsive repair agents without damaging surrounding tissues, and combines radiofrequency treatment (energy 15-30J / cm 2 ) to stimulate the contraction and reorganization of collagen fibers; the subcutaneous fat layer uses hydrodynamic-assisted liposuction technology, first injecting swelling fluid to separate fat cells, and then injecting temperature-sensitive repair agents, while coordinating with cryolipolysis (temperature -5℃--10℃, action time 20-30 minutes) to enhance the fat decomposition effect; the fascia layer is repaired with the assistance of an ultrasonic knife, with an ultrasonic frequency of 1.5-3.0MHz, to stimulate the firming of the fascia layer, and at the same time combined with absorbable thread lifting technology to lift and fix the loose fascia.

[0012] Specifically, the real-time feedback monitoring adopts a multi-parameter sensor array to monitor the changes of parameters such as tissue temperature, conductivity, and elastic modulus in real time during the repair process of each layer. When the tissue temperature rises abnormally (more than 1°C above normal body temperature), it indicates that there may be excessive repair or inflammatory response, and the injection dose of the repair agent or the intensity of physical intervention is adjusted immediately; if the conductivity changes by more than 10% of the normal range, it indicates that the tissue moisture content or ion concentration has changed, which may affect the diffusion of the repair agent, and the repair agent formula or administration method is adjusted accordingly; elastic modulus monitoring is used to evaluate the tissue repair effect. When the elastic modulus recovers to more than 80% of the normal range, it is determined that the repair of this level has basically met the standards and can enter the next level of repair.

[0013] Specifically, the interval between adjacent layer repairs is determined based on the test results of tissue healing markers at each layer. After the epidermis is repaired, when the keratinocyte proliferation rate recovers to more than 70% of the normal level and the epidermal barrier function index (transepidermal water loss value recovers to the normal range) meets the standard, the dermis is repaired, and the interval is usually 3 to 5 days; after the dermis is repaired, collagen synthesis is evaluated by detecting the hydroxyproline content. When the hydroxyproline content reaches more than 60% of the normal level and the elasticity of the dermis is restored to a certain extent (detected by a skin elasticity meter), the subcutaneous fat layer is repaired, and the interval is generally 7 to 10 days; after the subcutaneous fat layer is repaired, based on the recovery of fat cell metabolism markers (such as triglyceride levels) and subcutaneous tissue thickness, when the triglyceride level drops to within 1.5 times the normal range and the subcutaneous tissue thickness is close to normal, the fascia layer is repaired, and the interval is about 10 to 14 days.

[0014] Specifically, after each layer is repaired, a personalized maintenance plan is implemented. After the epidermis is repaired, a repair cream containing ceramide and squalane is used, applied 2 to 3 times a day for 1-2 weeks to promote epidermal barrier repair; after the dermis is repaired, a low-sensitivity collagen essence is used in combination with an introduction instrument for introduction treatment, 2 to 3 times a week for a total of 4-6 weeks to enhance the support of the dermis; after the subcutaneous fat layer is repaired, a moderate facial massage is performed (pressure 0.02-0.05MPa, 15 to 20 minutes each time, 3 to 4 times a week) to promote the excretion of fat metabolites, and combined with dietary adjustments (control high-fat food intake) for 1-2 months; after the fascia layer is repaired, avoid violent facial expressions for 1-2 weeks, and use a firming and lifting mask (containing peptides and other ingredients) 1 to 2 times a week to maintain the firming effect of the fascia layer.

[0015] Specifically, before restoration, a comprehensive facial function assessment is conducted on the patient, including facial expression muscle movement function, chewing function, speech function, etc. The changes in facial expression are recorded through three-dimensional motion capture technology, and the coordination of facial muscle movement is analyzed; the chewing function is detected using a bite force testing instrument; and the clarity and fluency of speech are evaluated through voice analysis software. According to the evaluation results, the focus of repair at each level is adjusted in a targeted manner in the restoration plan. For example, for patients with abnormal facial muscle movement, when repairing the dermis and fascia layers, the focus is on adjusting the mechanical balance between muscles and fascia to improve the naturalness of expression; for patients with affected chewing function, when repairing the subcutaneous fat layer and fascia layer, attention is paid to the repair of the masseter muscle attachment point and surrounding tissues to restore normal chewing function.

[0016] Specifically, a long-term follow-up mechanism is established after the repair. Through regular (1 month, 3 months, 6 months, and 1 year after the repair) facial imaging reviews (using the same multimodal image fusion technology as before the repair), skin physiological index testing (such as elasticity, moisture content, pigmentation), and patient subjective satisfaction surveys, the durability of the repair effect is comprehensively evaluated. If signs of diminished repair effect are found (such as skin sagging again, a small amount of filler recurrence, etc.), a secondary repair plan is formulated according to the follow-up data. The secondary repair plan is optimized based on the detailed records of the initial repair and new problems arising during the follow-up period, further improving the long-term effectiveness and stability of bun-shaped face repair.

[0017] Additional aspects and advantages of the present invention will be set forth in part in the description which follows and, in part, will be obvious from the description which follows, or may be learned through practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The above and / or additional aspects and advantages of the present invention will become apparent and readily understood from the following description of the embodiments in conjunction with the accompanying drawings, in which:

[0019] Figure 1 This is a schematic diagram of the functional evaluation process before restoration of the scalloped face layered restoration method of the present invention;

[0020] Figure 2 This is a flow chart of the imaging diagnosis and solution design process of the layered repair method for rounded face according to the present invention;

[0021] Figure 3 This is a schematic diagram of the epidermal layer repair and monitoring process of the layered repair method for scalloped face according to the present invention;

[0022] Figure 4 This is a schematic diagram of the dermis repair and monitoring process of the scalloped face layer repair method of the present invention;

[0023] Figure 5 This is a schematic diagram of the subcutaneous fat layer repair and monitoring process of the steamed face layer repair method of the present invention;

[0024] Figure 6 This is a schematic diagram of the fascia layer repair and monitoring process of the layered repair method for the scalloped face according to the present invention;

[0025] Figure 7 Schematic diagram of the maintenance process of each layer of the layered repair method for scalloped face according to the present invention;

[0026] Figure 8 Schematic diagram of the long-term follow-up and evaluation process of the layered repair method for the scalloped face according to the present invention. DETAILED DESCRIPTION

[0027] The embodiments of the present invention are described in detail below. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention and are not to be construed as limiting the present invention. On the contrary, the embodiments of the present invention include all variations, modifications, and equivalents that fall within the spirit and scope of the appended claims.

[0028] The following describes a method for repairing a cherubic face in layers according to an embodiment of the present invention with reference to the accompanying drawings.

[0029] like Figures 1-8 As shown, the layered repair method for a piquant face according to an embodiment of the present invention includes the following steps: utilizing multimodal image fusion technology in combination with high-resolution ultrasound imaging and near-infrared spectral analysis to obtain detailed structural, filler distribution, and tissue activity information of each facial layer (epidermis, dermis, subcutaneous fat layer, and fascia layer), and constructing a three-dimensional digital facial model; based on the model analysis results, customizing an exclusive repair plan for each layer, the plan includes a repair agent with a layer-specific activation mechanism and supporting physical intervention measures; starting from the epidermis and repairing in sequence to the deeper layers, the repair parameters are adjusted based on real-time feedback monitoring after each layer is repaired, and the repair interval between adjacent layers is determined according to the healing process of the previous layer of tissue.

[0030] It should be noted that the multimodal image fusion technology described in this embodiment is not a simple superposition of two imaging methods, but rather a pixel-level fusion of ultrasonic structural imaging and near-infrared component analysis data through an algorithm, so that the three-dimensional model simultaneously has "morphology-composition-activity" three-dimensional information, solving the problem that a single image is difficult to take into account both structural details and component identification; the layered repair sequence follows the nutrient delivery direction of the skin's physiological structure, avoiding mechanical damage to shallow repaired tissues caused by deep repairs; the real-time feedback and interval adjustment mechanism form a dynamic closed loop, which can be flexibly adapted according to individual tissue healing differences to ensure the stability and safety of the repair effect.

[0031] Furthermore, in multimodal image fusion technology, the resolution of high-resolution ultrasound imaging reaches 0.05mm, which can clearly distinguish the details of tissue structure at each level; near-infrared spectral analysis can identify the characteristic spectra of various fillers such as hyaluronic acid, collagen, autologous fat, and accurately locate the distribution of fillers at different levels, with an identification accuracy rate of more than 95%. Through the fusion of the two, the thickness of each level, filler volume and position information can be accurately presented in the three-dimensional digital facial model, providing a basis for customized repair plans.

[0032] It should be noted that the 0.05mm ultrasound resolution described in this embodiment is designed based on the average thickness of each facial layer (epidermis about 0.05-0.1mm, dermis about 0.5-2mm), which can just capture the subtle structural changes at the junction of the epidermis and dermis; the 95% recognition accuracy of the near-infrared spectrum is achieved by establishing a filler spectral database of 1000+ clinical samples, which can effectively distinguish fillers with similar chemical structures (such as cross-linked and non-cross-linked hyaluronic acid); after the two are fused, the error rate of the three-dimensional model is controlled within 3%, providing a reference basis with millimeter-level accuracy for the calculation of the amount of repair agent and the setting of the physical intervention range.

[0033] Furthermore, the repair agent with a layer-specific activation mechanism uses a light-activated repair agent in the epidermal layer, which contains epidermal growth factor and antioxidants encapsulated in photosensitive liposomes. Under light of a specific wavelength (400-450nm), the liposomes rupture and release active ingredients, promoting epidermal cell proliferation and barrier repair; the dermis uses a pH-responsive repair agent, which contains hyaluronidase and collagen synthesis promoter loaded with pH-sensitive polymer microspheres. Under the pH value of the dermis (about 7.0-7.4), the microspheres degrade and release drugs, decomposing excess fillers and stimulating collagen regeneration; the subcutaneous fat layer uses a temperature-sensitive repair agent, which encapsulates lipolytic enzymes with thermosensitive hydrogels. When the temperature reaches 37°C, the hydrogel swells and releases the enzyme, accurately decomposing excess fat cells; the fascia layer uses a mechanical-responsive repair agent, which is composed of fascia repair peptides carried by stretchable nanofiber carriers. When the fascia is stretched, the nanofiber structure changes and releases peptides, promoting fascia elasticity recovery.

[0034] It should be noted that the layer-specific activation mechanism described in this embodiment is highly matched with the physiological environment of each layer: the epidermis is exposed to light on a daily basis, so the light activation mechanism can be used to precisely control the release timing through external light; the pH value of the dermis is relatively stable (7.0-7.4), and the pH-responsive microspheres can avoid premature release in the epidermis (pH is about 5.5); the core temperature of the subcutaneous fat layer is close to 37°C, and the temperature-sensitive hydrogel can reduce the impact on the low temperature environment of the epidermis; the fascia layer is continuously subjected to force with facial movement, and the mechanically responsive carrier can synchronously release repair peptides during facial expressions, realizing dynamic synergy of "movement-repair" and greatly improving targeting and utilization.

[0035] Furthermore, in the photoactivated repair agent of the epidermal layer, the particle size of the photosensitive liposome is 100-200nm, the encapsulation rate of epidermal growth factor is not less than 80%, and the antioxidant is ferulic acid with a mass fraction of 0.5% to 1.5%; in the pH-responsive repair agent of the dermis layer, the particle size of the pH-sensitive polymer microspheres is 50-100μm, and the hyaluronidase loading is 5% to 10% of the microsphere mass; in the temperature-sensitive repair agent of the subcutaneous fat layer, the lower critical solution temperature of the thermosensitive hydrogel is 37°C, the specific activity of the lipolytic enzyme is 500-1000U / mg, and the encapsulation rate is not less than 70%; in the mechanical-responsive repair agent of the fascia layer, the diameter of the stretchable nanofibers is 50-100nm, and the loading amount of the fascia repair peptide is 10-50μg per mg of nanofibers.

[0036] It should be noted that the parameters of the repair agent described in this example were optimized through orthogonal experiments: The 100-200 nm particle size of the epidermal liposomes allows them to penetrate the stratum corneum but not the dermis, preventing waste of active ingredients; an encapsulation efficiency exceeding 80% ensures that epidermal growth factor is not enzymatically degraded during transport; a concentration of 0.5% to 1.5% ferulic acid provides antioxidant benefits without inhibiting cell proliferation. The 50-100 μm microspheres in the dermis can remain in the dermis for 7-10 days, matching the collagen synthesis cycle; and an enzyme loading of 5% to 10% balances degradation efficiency with microsphere stability. The specific enzyme activity of 500-1000 U / mg in the subcutaneous fat layer ensures that the degradation rate matches fat metabolism, and an encapsulation efficiency exceeding 70% minimizes enzyme inactivation during injection. The diameter of the nanofibers in the fascia layer is close to that of fascial collagen fibers (50-200 nm), enhancing biocompatibility. A loading of 10-50 μg / mg prevents excessive fascia contraction caused by excessive peptide dosage.

[0037] Furthermore, supporting physical intervention measures are designed in coordination with the needs of layer repair: the epidermis uses microcurrent introduction technology, combined with nano-microneedles to open the stratum corneum channel, with a microcurrent intensity of 0.1-0.5 mA to promote the penetration of light-activated repair agents, while low-energy red light irradiation (wavelength 630-660nm, energy density 5-10J / cm 2 ) to enhance the activity of epidermal cells; the dermis layer uses focused ultrasound (frequency 5-8MHz) to promote the uniform diffusion of pH-responsive repair agents without damaging surrounding tissues, and combines radiofrequency treatment (energy 15-30J / cm 2 ) to stimulate the contraction and reorganization of collagen fibers; the subcutaneous fat layer uses hydrodynamic-assisted liposuction technology, first injecting swelling fluid to separate fat cells, and then injecting temperature-sensitive repair agents, while coordinating with cryolipolysis (temperature -5℃--10℃, action time 20-30 minutes) to enhance the fat decomposition effect; the fascia layer is repaired with the assistance of an ultrasonic knife, with an ultrasonic frequency of 1.5-3.0MHz, to stimulate the firming of the fascia layer, and at the same time combined with absorbable thread lifting technology to lift and fix the loose fascia.

[0038] It should be noted that the physical intervention and the repair agent described in this embodiment form a synergistic effect of "1+1>2": the 0.1-0.5 mA microcurrent in the epidermis can enhance the penetration efficiency of liposomes through the electroporation effect, the 630-660 nm red light does not interfere with the 400-450 nm activation light of the photoactivated repair agent, and can also promote cell metabolism. The mechanical vibration of the 5-8 MHz focused ultrasound in the dermis can break the physical barrier of the dermal collagen fiber network and promote the uniform distribution of microspheres; 15-30 J / cm 2 Radiofrequency energy elevates the dermis to 38-40°C, enhancing the activity of collagen synthesis promoters. Hydrodynamic separation of the subcutaneous fat layer widens the gaps between adipocytes, increasing the contact area of ​​the repair agent by over 30%. Cryolipolysis at -5°C to 10°C disrupts the adipocyte membrane, enhancing the efficiency of lipolytic enzymes. 1.5-3.0MHz ultrasonic scalpel therapy stimulates the denaturation and contraction of fascial collagen, creating an immediate and long-term firming effect when combined with the mechanical lifting of absorbable sutures, complementing the sustained effect of mechanically responsive repair agents.

[0039] Furthermore, real-time feedback monitoring uses a multi-parameter sensor array to monitor changes in parameters such as tissue temperature, conductivity, and elastic modulus in real time during the repair process of each layer. When the tissue temperature rises abnormally (more than 1°C above normal body temperature), it indicates that there may be excessive repair or inflammatory response, and the injection dose of the repair agent or the intensity of physical intervention is adjusted immediately; if the conductivity change exceeds the normal range by 10%, it indicates that the tissue moisture content or ion concentration has changed, which may affect the diffusion of the repair agent, and the repair agent formula or administration method is adjusted accordingly; elastic modulus monitoring is used to evaluate the tissue repair effect. When the elastic modulus recovers to more than 80% of the normal range, it is determined that the repair at this level has basically met the standards and can enter the next level of repair.

[0040] It should be noted that the multi-parameter monitoring described in this embodiment forms a complementary verification system: tissue temperature monitoring can provide early warning of inflammation (local temperature rises by more than 1°C during inflammation), and avoid aggravating inflammation by reducing the intensity of physical intervention or reducing the dosage of repair agents (such as lipolytic enzymes). Changes in conductivity reflect changes in the tissue microenvironment (such as edema leading to increased conductivity). At this time, adjusting the osmotic pressure of the repair agent (such as increasing the concentration of hyaluronic acid) or using pulsed administration can improve the diffusion efficiency. The elastic modulus is a direct quantitative indicator of the repair effect. The 80% threshold value is set with reference to the elasticity data of various levels of the face of healthy people. It not only ensures a significant repair effect, but also reserves space for tissue adaptation for subsequent level repairs, avoiding the risk of over-repair due to the pursuit of 100% recovery.

[0041] Furthermore, the interval between adjacent layer repairs is determined based on the test results of tissue healing markers at each layer. After the epidermis is repaired, when the keratinocyte proliferation rate recovers to more than 70% of the normal level and the epidermal barrier function index (transepidermal water loss value recovers to the normal range) meets the standard, the dermis is repaired, and the interval is usually 3 to 5 days; after the dermis is repaired, collagen synthesis is evaluated by detecting the hydroxyproline content. When the hydroxyproline content reaches more than 60% of the normal level and the elasticity of the dermis is restored to a certain extent (detected by a skin elasticity meter), the subcutaneous fat layer is repaired, and the interval is generally 7 to 10 days; after the subcutaneous fat layer is repaired, based on the recovery of fat cell metabolism markers (such as triglyceride levels) and subcutaneous tissue thickness, when the triglyceride level drops to within 1.5 times the normal range and the subcutaneous tissue thickness is close to normal, the fascia layer is repaired, and the interval is about 10 to 14 days.

[0042] It should be noted that the repair interval described in this embodiment is highly matched with the tissue healing cycle: the 3-5 day interval of the epidermis corresponds to the migration cycle of keratinocytes (about 48-72 hours), and the 70% proliferation rate and normal transepidermal water loss value ensure that the epidermal barrier is firmly rebuilt, avoiding drug penetration and interference with the epidermis during dermal repair. The 7-10 day interval of the dermis matches the collagen synthesis cycle (hydroxyproline reaches a peak 7 days after repair), and the 60% hydroxyproline content ensures that the new collagen is sufficient to support subsequent operations. The 10-14 day interval of the subcutaneous fat layer is consistent with the fat metabolism cycle (the half-life of triglyceride metabolism is about 10 days), and the triglyceride level within 1.5 times avoids the accumulation of metabolites that affect fascia repair. Determining the interval by healing markers rather than fixed times can adapt to the individual differences of patients of different ages and skin conditions, thereby improving the universality of the solution.

[0043] Furthermore, after each layer is repaired, a personalized maintenance plan is implemented. After the epidermis is repaired, a repair cream containing ceramide and squalane is used, applied 2 to 3 times a day for 1-2 weeks to promote epidermal barrier repair; after the dermis is repaired, a low-sensitivity collagen essence is used in combination with an introduction instrument for introduction treatment, 2 to 3 times a week for a total of 4-6 weeks to enhance the support of the dermis; after the subcutaneous fat layer is repaired, a moderate facial massage (pressure 0.02-0.05MPa, 15 to 20 minutes each time, 3 to 4 times a week) is performed to promote the excretion of fat metabolites, and combined with dietary adjustments (control high-fat food intake) for 1-2 months; after the fascia layer is repaired, avoid violent facial expressions for 1-2 weeks, and use a firming and lifting mask (containing peptides and other ingredients) 1 to 2 times a week to maintain the firming effect of the fascia layer.

[0044] It should be noted that the personalized maintenance regimen described in this example extends and consolidates the repair process: ceramides and squalane in the epidermis replenish epidermal lipids, with their ratio (3:1) mimicking the composition of a healthy epidermal barrier. Continuous use for 1-2 weeks matches the epidermal renewal cycle (28 days), reducing the risk of post-repair sensitivity. The frequency of collagen serum application in the dermis (2-3 times per week) is synchronized with the rate of collagen fiber cross-linking, and a 4-6 week cycle covers the critical period of collagen remodeling (collagen structure stabilizes 4-6 weeks after repair). Massaging pressure (0.02-0.05 MPa) in the subcutaneous fat layer promotes lymphatic circulation without damaging adipocytes. A low-fat diet can reduce the formation of new adipocytes, and a 1-2 month cycle ensures complete excretion of metabolic products. Restricting facial expressions in the fascia for 1-2 weeks prevents excessive stress on the newly repaired fascia. Acetyl hexapeptide-8 in the peptide mask inhibits excessive fascia contraction, forming a long-lasting synergistic effect with the repair agent to maintain the firming effect.

[0045] Furthermore, before restoration, a comprehensive facial function assessment is conducted on the patient, including facial expression muscle movement function, chewing function, speech function, etc. The changes in facial expression are recorded by three-dimensional motion capture technology, and the coordination of facial muscle movement is analyzed; the chewing function is detected using a bite force testing instrument; and the clarity and fluency of speech are evaluated through voice analysis software. According to the evaluation results, the focus of each level of restoration is adjusted in a targeted manner in the restoration plan. For example, for patients with abnormal facial muscle movement, when repairing the dermis and fascia layers, the focus is on adjusting the mechanical balance between muscles and fascia to improve the naturalness of expression; for patients with affected chewing function, when repairing the subcutaneous fat layer and fascia layer, attention is paid to the repair of the masseter muscle attachment point and surrounding tissues to restore normal chewing function.

[0046] It should be noted that the facial function assessment described in this embodiment breaks through the limitations of traditional focus on appearance repair and incorporates functional restoration into the core goal: three-dimensional motion capture can quantify the range of motion of facial muscles (error <1mm), identify facial muscle synergia caused by excessive filling (such as asymmetric smile), and provide a mechanical adjustment basis for the repair of the dermis (attachment of facial muscles) and fascia (fulcrum of facial muscle movement). The bite force test (accuracy 0.1kg) can locate the functional abnormalities of the masseter and temporalis muscles, guide the operation depth during the repair of the subcutaneous fat layer (fat around the masseter muscle) and fascia layer (massage muscle fascia), and avoid excessive repair affecting the chewing strength. The speech function assessment analyzes the vibration frequency of facial tissue during vowel pronunciation (accuracy 1Hz), identifies speech disorders caused by filling and compressing the vocal cords or oral structures, and adjusts the amount of repair agent at the corresponding level. The linkage between functional assessment and repair plan ensures that the repair effect takes into account both "natural appearance" and "normal function".

[0047] Furthermore, a long-term follow-up mechanism is established after the repair. Through regular (1 month, 3 months, 6 months, and 1 year after the repair) facial imaging reviews (using the same multimodal image fusion technology as before the repair), skin physiological index testing (such as elasticity, moisture content, pigmentation), and patient subjective satisfaction surveys, the durability of the repair effect is comprehensively evaluated. If signs of diminished repair effect are found (such as skin sagging again, a small amount of filler recurrence, etc.), a secondary repair plan is formulated according to the follow-up data. The secondary repair plan is optimized based on the detailed records of the initial repair and new problems arising during the follow-up period, further improving the long-term effectiveness and stability of bun-shaped face repair.

[0048] It should be noted that the long-term follow-up mechanism described in this embodiment forms a closed loop of "repair-evaluation-optimization": 1-month follow-up evaluates the acute repair effect (such as the disappearance of inflammation), 3-month evaluation of collagen remodeling stability, 6-month and 1-year evaluation of long-term effects (fat metabolism, fascia elasticity maintenance), and time points are set to cover the key nodes of facial tissue repair. Multimodal imaging review and comparison of initial data can quantify the thickness changes of each layer (accuracy 0.01mm) and the residual volume rate of filler (error <5%) to avoid subjective evaluation bias. The secondary repair plan is not a simple repetition of the initial operation, but by analyzing the follow-up data to locate the cause of the decline (such as too rapid degradation of dermal collagen or insufficient fascia elasticity), and to adjust the type of repair agent (such as switching to a long-acting collagen promoter) or the intensity of physical intervention to achieve "precise repair". Long-term follow-up and secondary optimization mechanisms solve the problem of short-term repair effects of existing technologies and ensure the long-term stability of the repair effect of the bun-shaped face.

[0049] Example 1: Mild scalloped face repair (filler volume ≤ 2 ml, facial muscle coordination deviation 10% to 20%)

[0050] (1) Functional assessment before restoration

[0051] Facial expression muscle movement assessment: A three-dimensional motion capture system (accuracy 0.1mm) was used to record facial expressions such as smiling and frowning. Analysis showed that the movement range of the apple muscle area was stiff, and the coordination of the facial muscles deviated by 15% compared with the standard value of healthy women aged 25-35 years (based on 100 sample statistics) (normal deviation range ≤5%).

[0052] Evaluation of chewing function: The bite force test instrument (accuracy 0.1kg) showed that the maximum bite force was 35kg (the standard value for healthy women aged 25-35 years is 40±5kg), which was 10% lower than the standard value, and there was no chewing pain.

[0053] Speech function assessment: Speech analysis software (sampling rate 44.1kHz) showed that the speech intelligibility was 90% (normal ≥95%), the labiodental pronunciation delay was 0.2s (normal ≤0.1s), and the fluency score was 85 points (full score 100 points, normal ≥90 points).

[0054] (2) Imaging diagnosis and program design

[0055] Multimodal image fusion diagnosis:

[0056] High-resolution ultrasound imaging: resolution 0.05mm, showing epidermal thickness 0.08mm (normal 0.06-0.1mm), dermal thickness 1.2mm (normal 0.8-1.5mm), subcutaneous fat layer in the apple muscle area 6mm (normal 3-5mm), and complete continuity of the fascia layer.

[0057] Near-infrared spectroscopy analysis: 97% recognition accuracy, positioning of hyaluronic acid fillers in the apple muscles and temples (characteristic peak 1040cm -1 ), distributed in the dermis (0.8 ml) and the superficial layer of subcutaneous fat (0.7 ml), with a total volume of 1.5 ml.

[0058] Construct a 3D digital facial model: Generate a model by fusing image data, accurately mark the position of fillers (error ≤ 0.1mm) and the thickness deviation of each layer (such as a 20% thickening of the subcutaneous fat layer).

[0059] Customized layered repair solutions:

[0060] Preparation of layer-specific repair agents:

[0061] Epidermis: Light-activated repair agent, photosensitive liposomes (soy lecithin: cholesterol = 3:1, prepared by ultrasonic emulsification in a 40°C water bath for 15 minutes), particle size 120nm, epidermal growth factor (EGF) encapsulation efficiency 85% (detected by high-performance liquid chromatography), ferulic acid mass fraction 1%.

[0062] Dermis: pH-responsive repair agent, pH-sensitive polymer microspheres (polyethylene glycol-polyβ-amino ester copolymer, initiator dosage 2%), particle size 60 μm, hyaluronidase loading 6% (determined by UV spectrophotometry), proline mass fraction 0.3%.

[0063] Subcutaneous fat layer: temperature-sensitive repair agent, temperature-sensitive hydrogel (poly N-isopropylacrylamide, cross-linking agent dosage 1%), lower critical solution temperature 37°C, lipolytic enzyme specific activity 600 U / mg (determined by substrate method), encapsulation rate 75%.

[0064] Fascia layer: mechanically responsive repair agent, stretchable nanofiber (polycaprolactone, electrospinning voltage 15kV) with a diameter of 60nm, and a fascia repair peptide (sequence Gly-Pro-Hyp) loading of 20μg / mg (detected by amino acid analyzer).

[0065] Supporting physical intervention parameters: epidermal microcurrent 0.2mA + red light 640nm (5J / cm 2 ), dermal focused ultrasound 6MHz + radiofrequency 18J / cm 2 , hydrodynamic liposuction + cryolipolysis of subcutaneous fat layer (-8℃, 25 minutes), ultrasonic knife 2MHz + 3-0 absorbable thread (lifting angle 15°) on fascia layer.

[0066] (3) Epidermal repair and monitoring

[0067] Repair procedure: After the stratum corneum is opened with nano-microneedles (50 μm in diameter), a light-activated repair agent is introduced with a 0.2 mA microcurrent and irradiated with 440 nm blue light for 10 minutes (activation release efficiency 80%, verified by HPLC).

[0068] Real-time monitoring and adjustment:

[0069] The tissue temperature was maintained at 36.5±0.5°C (infrared thermometer), the conductivity was 45±5mS / cm (normal range 40-50mS / cm), and the elastic modulus (Cutometer MPA580) reached 18N / m (standard value for healthy women aged 25-35 years old 20±2N / m) after 7 days of repair, recovering to 85% of the normal range.

[0070] If the temperature rises to 37.5°C, immediately reduce the red light energy density by 10%; if the conductivity fluctuation exceeds 5mS / cm, increase the glycerol content in the repair agent by 0.5%.

[0071] Maintenance phase: Repair cream containing ceramide (3%) + squalane (2%) 3 times a day, after 1 week, the transepidermal water loss value (TEWL) is restored to 12g / (m 2 ·h)(normal range 10~15g / (m 2 ·h)).

[0072] (IV) Dermis repair and monitoring

[0073] Repair operation: After the epidermis is repaired to the standard, the pH-responsive repair agent is treated with 6MHz focused ultrasound (power 0.5W / cm 2 ) is introduced into the dermis, with a radiofrequency of 18J / cm 2 Act on the collagen layer (temperature reaches 42°C, lasts for 3 seconds).

[0074] Real-time monitoring and adjustment:

[0075] If the temperature rises to 38.5°C (normal ≤ 39°C) during radiofrequency treatment, immediately reduce the radiofrequency energy by 10% (to 16.2 J / cm 2 ), the temperature dropped to 37.8℃.

[0076] The elastic modulus reached 45 N / m after 7 days (the standard value for healthy women aged 25-35 is 55±5 N / m), recovering to 82%; the hydroxyproline content (HPLC method) reached 35 μg / mg (normal range 40-50 μg / mg).

[0077] Maintenance stage: Collagen essence (1%) was introduced twice a week. After 4 weeks, the thickness of the dermis was restored to 1.1mm (close to the normal 1.0mm).

[0078] (5) Repair and monitoring of the subcutaneous fat layer

[0079] Repair operation: After the dermis layer is repaired to the standard, hydrodynamic liposuction (0.03MPa) is performed to separate fat cells 7 days later. After injecting temperature-sensitive repair agent, cryolipolysis is performed (-8℃, 25 minutes).

[0080] Real-time monitoring and adjustment:

[0081] During the freezing process, the tissue temperature dropped to 32°C (safe range 30-34°C), and the elastic modulus reached 2.5kPa after 10 days (the standard value for healthy women aged 25-35 is 3.1±0.3kPa), recovering to 80%.

[0082] The triglyceride level (enzymatic assay) dropped to 1.2 mmol / L (normal range 0.5-1.7 mmol / L).

[0083] Maintenance stage: 0.03MPa massage (15 minutes / time) 3 times a week. After 1 month, the thickness of the subcutaneous fat layer dropped to 5mm (normal 4-5mm).

[0084] (6) Fascia layer repair and monitoring

[0085] Repair operation: After the subcutaneous fat layer is repaired to the standard, wait 10 days and use ultrasonic knife 2MHz (energy 0.8J / cm 2 ) acts on the fascia layer, 3-0 absorbable suture is pulled along the direction of the zygomatic arch ligament (angle 15°, tension 50g), and a mechanical responsive repair agent is injected.

[0086] Real-time monitoring and adjustment:

[0087] The elastic modulus (shear wave elastography) reached 8 kPa (standard value for healthy women aged 25-35 years: 9.5±1 kPa) 14 days after ultrasonic scalpel treatment, recovering to 85%.

[0088] Maintenance stage: Avoid intense facial expressions such as laughing for 1 week, and use a firming mask (containing 2% acetyl hexapeptide-8) once a week.

[0089] Example 2: Repair of moderately swelled face (filler volume 2-4 ml, facial muscle coordination deviation 20%-40%)

[0090] (1) Functional assessment before restoration

[0091] The deviation of facial muscle coordination is 30% (standard value for healthy women aged 25-35 years), the maximum bite force is 32kg (standard value 40±5kg), and the speech clarity is 80% (normal ≥95%).

[0092] (2) Imaging diagnosis and program design

[0093] Multimodal imaging revealed a total filler volume of 3ml (2ml hyaluronic acid + 1ml autologous fat), uneven dermal thickness (1.2-1.5mm), and a maximum subcutaneous fat layer thickness of 8mm. Repair agent parameters: 1.2% ferulic acid in the epidermis, 8% hyaluronidase loading in the dermis, 700U / mg lipolysis enzyme specific activity in the subcutaneous fat layer, and 30μg / mg repair peptide loading in the fascia layer. Physical intervention: 8J / cm red light energy in the epidermis. 2 , dermal radiofrequency 22J / cm 2 The subcutaneous fat layer was frozen at -6℃ and the fascia layer was treated with an ultrasonic knife at 2.5MHz.

[0094] (3) Key repair data

[0095] Epidermis: Elastic modulus 17N / m (normal 20±2N / m) after 10 days of repair, TEWL 13g / (m 2 ·h).

[0096] Dermis: When the temperature rises to 39°C during radiofrequency treatment, the energy drops to 19.8 J / cm 2 (Decreased by 10%), hydroxyproline 38μg / mg after 10 days (normal 40-50μg / mg).

[0097] Subcutaneous fat layer: elastic modulus 2.3 kPa after 12 days (normal 3.1±0.3 kPa), triglyceride 1.4 mmol / L.

[0098] Long-term follow-up: After 3 months, the elasticity increased by 25% (the control group with single radiofrequency increased by 10%), and the filler residual rate was 0% (the control group had 8%).

[0099] Example 3: Severely rounded face repair (filler volume ≥ 4ml, facial muscle coordination deviation ≥ 40%)

[0100] (1) Functional assessment before restoration

[0101] The deviation of facial muscle coordination was 50%, the maximum bite force was 24 kg (standard value 40 ± 5 kg), and the speech clarity was 60% (normal ≥ 95%).

[0102] (2) Imaging diagnosis and program design

[0103] Multimodal imaging revealed a total filler volume of 5ml (3ml of hyaluronic acid, 1.5ml of autologous fat, and 0.5ml of an unidentified filler), a dermal layer thickness of 2mm, and a maximum subcutaneous fat layer thickness of 10mm. Repair agent parameters: 1.5% ferulic acid in the epidermis, 10% hyaluronidase loading in the dermis, 1000U / mg lipolysis enzyme specific activity in the subcutaneous fat layer, and 50μg / mg repair peptide loading in the fascia layer. Physical intervention: 10J / cm red light in the epidermis. 2 , dermal radiofrequency 30J / cm 2 , secondary freezing and lipolysis of the subcutaneous fat layer, and ultrasonic knife 3MHz+5-0 absorbable thread on the fascia layer.

[0104] (3) Key repair data

[0105] Dermis: When the RF temperature rises to 40°C, pause for 2 minutes and reduce the energy to 27J / cm 2 (Decreased by 10%), hydroxyproline 36μg / mg after 14 days (normal 40-50μg / mg).

[0106] Subcutaneous fat layer: elastic modulus after secondary repair 2.1kPa (normal 3.1±0.3kPa), triglyceride 1.5mmol / L.

[0107] Long-term follow-up: 6 months later, the elasticity retention rate was 85% (40% in the control group with single radiofrequency), and the collagen fiber arrangement order was 75% (normal ≥80%).

[0108] In summary, the layered repair method for swelled facial skin in the embodiments of the present invention uses multimodal image fusion to precisely locate fillers and structural abnormalities at each facial layer. A customized solution containing layer-specific activating repair agents and accompanying physical interventions is then applied sequentially from the epidermis to the fascia. This method, combined with real-time monitoring and dynamic adjustment, determines repair intervals based on tissue healing markers to achieve precise layered repair. This method addresses the prior art's inability to achieve precise layered repair. By utilizing layer-specific repair agents, coordinated physical interventions, and dynamic adjustment mechanisms, targeted repair is achieved at each layer, improving the accuracy and durability of the repair effect.

[0109] Although the embodiments of the present invention have been shown and described above, it will be understood that the above embodiments are exemplary and are not to be construed as limitations on the present invention. A person skilled in the art may change, modify, replace and deform the above embodiments within the scope of the present invention.

Claims

1. A method for repairing a rounded face by layers, characterized in that: The following steps are involved: Utilizing multimodal image fusion technology, combined with high-resolution ultrasound imaging and near-infrared spectral analysis, we obtain detailed structural, filler distribution, and tissue activity information of each facial layer (epidermis, dermis, subcutaneous fat, and fascia), and construct a three-dimensional digital facial model. Based on the model analysis results, we customize a repair plan for each layer, which includes a repair agent with a layer-specific activation mechanism and supporting physical intervention measures. Repair begins from the epidermis and progresses to the deeper layers. After each layer is repaired, the repair parameters are adjusted based on real-time feedback monitoring, and the repair interval between adjacent layers is determined according to the healing process of the previous layer of tissue.

2. The method according to claim 1, characterized in that In the multimodal image fusion technology, the resolution of high-resolution ultrasound imaging reaches 0.05mm, which can clearly distinguish the details of tissue structure at each level; near-infrared spectral analysis can identify the characteristic spectra of various fillers such as hyaluronic acid, collagen, autologous fat, and accurately locate the distribution of fillers at different levels. The recognition accuracy rate is higher than 95%. Through the fusion of the two, the thickness of each layer, the volume and position information of the filler can be accurately presented in the three-dimensional digital facial model, providing a basis for customized repair plans.

3. The method according to claim 1, characterized in that The repair agent with a layer-specific activation mechanism uses a light-activated repair agent in the epidermal layer, which contains epidermal growth factor and antioxidants encapsulated in photosensitive liposomes. Under light of a specific wavelength (400-450nm), the liposomes rupture and release active ingredients, promoting epidermal cell proliferation and barrier repair; the dermis uses a pH-responsive repair agent, which contains hyaluronidase and collagen synthesis promoter loaded with pH-sensitive polymer microspheres. Under the pH value of the dermis (about 7.0-7.4), the microspheres degrade and release drugs, decomposing excess fillers and stimulating collagen regeneration; the subcutaneous fat layer uses a temperature-sensitive repair agent, which encapsulates lipolytic enzymes with thermosensitive hydrogels. When the temperature reaches 37°C, the hydrogel swells and releases the enzyme, accurately decomposing excess fat cells; the fascia layer uses a mechanical-responsive repair agent, which is composed of fascia repair peptides carried by stretchable nanofiber carriers. When the fascia is stretched, the nanofiber structure changes and releases peptides, promoting fascia elasticity recovery.

4. The method according to claim 3, characterized in that In the photoactivated repair agent of the epidermal layer, the particle size of the photosensitive liposome is 100-200nm, the encapsulation rate of epidermal growth factor is not less than 80%, and the antioxidant is ferulic acid with a mass fraction of 0.5% to 1.5%; in the pH-responsive repair agent of the dermis layer, the particle size of the pH-sensitive polymer microspheres is 50-100μm, the hyaluronidase loading amount is 5% to 10% of the microsphere mass, and the collagen synthesis promoter is proline with a mass fraction of 0.2% to 0.8%; in the temperature-sensitive repair agent of the subcutaneous fat layer, the lower critical solution temperature of the thermosensitive hydrogel is 37°C, the specific activity of the lipolytic enzyme is 500-1000U / mg, and the encapsulation rate is not less than 70%; in the mechanical-responsive repair agent of the fascia layer, the diameter of the stretchable nanofibers is 50-100nm, and the loading amount of the fascia repair peptide is 10-50μg per mg of nanofibers.

5. The method according to claim 1, wherein The supporting physical intervention measures are designed in coordination with the needs of layer repair: the epidermis uses microcurrent introduction technology, combined with nano-microneedles to open the stratum corneum channel, with a microcurrent intensity of 0.1-0.5 mA to promote the penetration of light-activated repair agents, and at the same time uses low-energy red light irradiation (wavelength 630-660nm, energy density 5-10J / cm 2 ) to enhance the activity of epidermal cells; the dermis layer uses focused ultrasound (frequency 5-8MHz) to promote the uniform diffusion of pH-responsive repair agents without damaging surrounding tissues, and combines radiofrequency treatment (energy 15-30J / cm 2 ) to stimulate the contraction and reorganization of collagen fibers; the subcutaneous fat layer uses hydrodynamic-assisted liposuction technology, first injecting swelling fluid to separate fat cells, and then injecting temperature-sensitive repair agents, while coordinating with cryolipolysis (temperature -5℃--10℃, action time 20-30 minutes) to enhance the fat decomposition effect; the fascia layer is repaired with the assistance of an ultrasonic knife, with an ultrasonic frequency of 1.5-3.0MHz, to stimulate the firming of the fascia layer, and at the same time combined with absorbable thread lifting technology to lift and fix the loose fascia.

6. The method according to claim 1, characterized in that The real-time feedback monitoring uses a multi-parameter sensor array to monitor changes in parameters such as tissue temperature, conductivity, and elastic modulus in real time during the repair process of each layer. When the tissue temperature rises abnormally (more than 1°C above normal body temperature), it indicates that there may be excessive repair or inflammatory response, and the injection dose of the repair agent or the intensity of physical intervention is adjusted immediately; if the conductivity change exceeds the normal range by 10%, it indicates that the tissue moisture content or ion concentration has changed, which may affect the diffusion of the repair agent, and the repair agent formula or administration method is adjusted accordingly; elastic modulus monitoring is used to evaluate the tissue repair effect. When the elastic modulus recovers to more than 80% of the normal range, it is determined that the repair of this level has basically met the standards and can enter the next level of repair.

7. The method according to claim 1, characterized in that The interval between adjacent layer repairs is determined based on the test results of tissue healing markers at each layer. After the epidermis is repaired, when the keratinocyte proliferation rate recovers to more than 70% of the normal level and the epidermal barrier function index (transepidermal water loss value returns to the normal range) meets the standard, the dermis is repaired, and the interval is usually 3 to 5 days; after the dermis is repaired, collagen synthesis is evaluated by testing the hydroxyproline content. When the hydroxyproline content reaches more than 60% of the normal level and the elasticity of the dermis is restored to a certain extent (detected by a skin elasticity meter), the subcutaneous fat layer is repaired, and the interval is generally 7 to 10 days; after the subcutaneous fat layer is repaired, based on the recovery of fat cell metabolism markers (such as triglyceride levels) and subcutaneous tissue thickness, when the triglyceride level drops to within 1.5 times the normal range and the subcutaneous tissue thickness is close to normal, the fascia layer is repaired, and the interval is about 10 to 14 days.

8. The method according to claim 1, characterized in that After each layer is repaired, a personalized maintenance plan is implemented. After the epidermis is repaired, a repair cream containing ceramide and squalane is used, applied 2 to 3 times a day for 1-2 weeks to promote epidermal barrier repair; after the dermis is repaired, a low-sensitivity collagen essence is used in combination with an introduction instrument for introduction treatment, 2 to 3 times a week for a total of 4-6 weeks to enhance the support of the dermis; after the subcutaneous fat layer is repaired, a moderate facial massage (pressure 0.02-0.05MPa, 15 to 20 minutes each time, 3 to 4 times a week) is performed to promote the excretion of fat metabolites, and combined with dietary adjustments (control high-fat food intake) for 1-2 months; after the fascia layer is repaired, avoid violent facial expressions for 1-2 weeks, and use a firming and lifting mask (containing peptides and other ingredients) 1 to 2 times a week to maintain the firming effect of the fascia layer.

9. The method according to claim 1, characterized in that Before restoration, a comprehensive facial function assessment is conducted on the patient, including facial expression muscle movement function, chewing function, speech function, etc. The changes in facial expression are recorded through three-dimensional motion capture technology, and the coordination of facial muscle movement is analyzed; the chewing function is detected using a bite force testing instrument; and the clarity and fluency of speech are evaluated through voice analysis software. According to the evaluation results, the focus of each level of restoration is adjusted in a targeted manner in the restoration plan. For example, for patients with abnormal facial muscle movement, when repairing the dermis and fascia layers, the focus is on adjusting the mechanical balance between muscles and fascia to improve the naturalness of expression; for patients with affected chewing function, when repairing the subcutaneous fat layer and fascia layer, attention is paid to the repair of the masseter muscle attachment point and surrounding tissues to restore normal chewing function.

10. The method according to claim 1, characterized in that After the repair, a long-term follow-up mechanism is established. Through regular facial imaging reviews (using the same multimodal image fusion technology as before the repair) (1 month, 3 months, 6 months, and 1 year after the repair), skin physiological index testing (such as elasticity, moisture content, pigmentation), and patient subjective satisfaction surveys, the durability of the repair effect is comprehensively evaluated. If signs of diminished repair effect are found (such as skin sagging again, a small amount of filler recurrence, etc.), a secondary repair plan is formulated according to the follow-up data. The secondary repair plan is optimized based on the detailed records of the initial repair and new problems arising during the follow-up period, further improving the long-term effectiveness and stability of bun-shaped face repair.

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