Temperature and humidity data monitoring and storing device for cold-chain transportation of in-vitro diagnostic reagent

Abstract

The invention relates to the field of medical instrument transportation, in particular to an in-vitro diagnostic reagent cold chain transportation temperature and humidity data monitoring and storing device. Comprising a protection box, an in-vitro diagnostic reagent storage assembly, an in-vitro diagnostic reagent limiting assembly, a temperature and humidity acquisition module, a communication module, a data storage module, a display module, a power supply module, a control module, a near field communication module, a man-machine interaction module, a refrigeration and heating module and a dehumidification and humidification module. According to the invention, cold chain monitoring temperature and humidity information in a specified time period can be rapidly obtained; information content obtained by scanning can be in butt joint with format data of various warehouse management platforms; a LoRa wireless technology with low power consumption is adopted, and a lithium battery is used for supplying power, so that the use cost and the maintenance workload are reduced; a high-precision temperature and humidity acquisition module and an electronic ink screen are used for displaying data in real time, so that the functions are rich and practical; the in-vitro diagnostic reagent storage assembly and the in-vitro diagnostic reagent limiting assembly are matched for use, and the stability of reagents in the transportation process is improved.

Description

Technical Field

[0001] The present invention relates to the field of medical device transportation, and in particular to a device for monitoring and storing temperature and humidity data during cold chain transportation of in vitro diagnostic reagents. Background Art

[0002] Cold chain transportation means that during the entire transportation process, whether it is loading and unloading, changing the mode of transportation, replacing packaging equipment, etc., the transported goods are always kept at a certain temperature. When in vitro diagnostic reagents are transported over long distances, it is necessary to ensure that the environment is in a cooling state and have strict temperature / humidity requirements to avoid loss of in vitro diagnostic reagents. Therefore, they are usually cooled and transported in protective boxes in cold chain transportation. Generally, a thermometer and hygrometer are installed in the protective box to monitor the process temperature.

[0003] After the protective box arrives at the destination, traditional thermometers and hygrometers print out temperature and humidity records during transportation. These records are generally printed on paper using a thermal printer. However, this paper version has many drawbacks, such as blurry printing, difficulty retaining and recording, inability to form traceability files, inability to link with information systems to form logistics process records, and the inability to customize printed content. Furthermore, it is impossible to register all necessary information in accordance with warehouse management requirements, making it difficult to meet the needs of modern cold chain transportation for temperature and humidity data monitoring and management of in vitro diagnostic reagents.

[0004] Therefore, those skilled in the art provide a device for monitoring and storing temperature and humidity data of cold chain transportation of in vitro diagnostic reagents to solve the problems raised in the above background technology. Summary of the Invention

[0005] In order to solve the above technical problems, the present invention provides a temperature and humidity data monitoring and storage device for the cold chain transportation of in vitro diagnostic reagents, so as to solve the problems of inconvenience of paper records, inability to connect with information systems, and single functions in the existing technology of temperature and humidity monitoring of in vitro diagnostic reagents in cold chain transportation, and realize convenient data acquisition, efficient information management and low-power long-term operation.

[0006] The protective box comprises a protective box, which is a hollow cavity with an opening on one side, a hinged door hinged on one side of the protective box, a sealing gasket connected between the hinged door and the protective box, an in vitro diagnostic reagent storage component connected to the inner top of the protective box, an in vitro diagnostic reagent limiting component connected to the inner bottom of the protective box, and a temperature and humidity acquisition module, a communication module, a data storage module, a display module, a power supply module, a control module, a near-field communication module, a human-computer interaction module, a cooling and heating module, and a dehumidification and humidification module are provided inside the protective box; the temperature and humidity acquisition module is used to collect temperature and humidity data in the protective box, the control module serves as the core control unit of the device, and is used to coordinate and control the operation of each module of the device; the power supply module supplies power to other modules.

[0007] Preferably, the control module receives the data collected by the temperature and humidity acquisition module, processes and analyzes the data, and controls each module to perform corresponding operations according to preset rules. At the same time, it manages the data storage and reading of the data storage module, and controls the communication module to transmit data; the power supply module uses a lithium battery to power the device, and uses low-power technology combined with intelligent sleep mode and smart screen mode to extend battery life.

[0008] Preferably, the temperature and humidity acquisition module is equipped with a high-precision temperature and humidity sensor with a temperature acquisition range of -20°C-60°C, an acquisition accuracy of 0.2°C, a resolution of 0.1°C, and a humidity acquisition range of 0%-100%RH, an acquisition accuracy of ±2%, and a resolution of 0.5%RH. It is used to collect temperature and humidity data in the protective box during cold chain transportation of in vitro diagnostic reagents in real time and transmit the collected data to the control module;

[0009] Preferably, the temperature and humidity acquisition module further includes a temperature and humidity calibration unit, which regularly calibrates the high-precision temperature and humidity sensor through a built-in standard temperature and humidity source to ensure the accuracy of the collected data.

[0010] Preferably, the communication module adopts the standard LoRaWAN communication protocol, connects to a compatible standard LoRaWAN gateway through LoRa wireless technology, and builds an intelligent communication cloud network with the Internet of Things platform to achieve remote data monitoring and management;

[0011] Preferably, the data storage module is used to locally store the data collected by the temperature and humidity collection module, supports the network disconnection data retransmission function and threshold warning. When the device is in a network disconnection state, the collected data is temporarily stored in the data storage module. After the network is restored, the temporarily stored data is transmitted back to the Internet of Things platform; when the stored data exceeds the preset temperature and humidity threshold, an alarm signal is sent to the control module; the data storage module adopts a non-volatile memory and is provided with a data encryption module for encrypting the stored temperature and humidity data to ensure data security; the display module adopts an electronic ink screen, and the electronic ink screen is arranged on the outside of the protective box and connected to the control module.

[0012] Preferably, the near field communication module is configured with an NFC module to support the collection of NFC wireless configurations for achieving rapid data transmission and device configuration modification.

[0013] Preferably, the human-computer interaction module is provided with physical buttons and is arranged on the outside of the protective box, providing a custom template batch configuration function, and can be connected with various warehouse management system data modes.

[0014] Preferably, the cooling and heating module is used to adjust the temperature inside the protective box, and is composed of a semiconductor cooling plate, a cooling fan, a heating wire and a corresponding control circuit.

[0015] Preferably, the dehumidification and humidification module is used to adjust the humidity inside the protective box, and is composed of a condensing dehumidifier, an ultrasonic humidifier and a humidity control circuit.

[0016] Preferably, the in vitro diagnostic reagent storage assembly includes a rotating shaft rotatably connected to the inner bottom of the in vitro diagnostic reagent storage assembly, a rotating disk fixedly connected to the upper end of the rotating shaft, the upper end of the rotating disk is connected to three groups of reagent placement mechanisms, and the inner bottom of the protective box is connected to a disk limiting assembly for limiting the rotating disk.

[0017] Preferably, the reagent placement mechanism includes a sliding mounting groove opened at the upper end of the rotating disk, a sliding mounting block slidingly connected to the inside of the sliding mounting groove, and a reagent placement barrel fixedly connected to the upper end of the sliding mounting block. The upper end of the reagent placement barrel is provided with multiple groups of reagent placement grooves, and the inner walls of the multiple groups of reagent placement grooves are fixedly connected with rubber rings, and the inner bottoms of the multiple groups of reagent placement grooves are fixedly connected with pressure sensors.

[0018] Preferably, a limiting receiving groove is provided on the inner walls on both sides of the sliding mounting groove, and a first spring is fixedly connected to the inner walls of the two groups of the limiting receiving grooves, one end of the two groups of the first springs is fixedly connected to the limiting member, and one end of the two groups of the limiting members are slidably connected to the inside of the sliding mounting groove, and a limiting adjustment groove is provided on one side of the two groups of the limiting receiving grooves, and one side of the two groups of the limiting members is fixedly connected to the limiting adjustment member, and the limiting adjustment member is slidably connected to the inside of the limiting member.

[0019] Preferably, the disk limiting assembly includes a limiting outer cylinder fixedly connected to the inner bottom of the protective box, a limiting inner shaft slidably connected to the inside of the upper end of the limiting outer cylinder, a limiting disk fixedly connected to the upper end of the limiting inner shaft, and a limiting column fixedly connected to the upper end of the limiting disk, and a second spring is fixedly connected between the limiting disk and the inner bottom of the protective box, and multiple groups of limiting grooves are provided at the lower end of the rotating disk, and the limiting column is slidably connected to the inside of a group of the limiting grooves, and the number of the limiting grooves is the same as that of the reagent placement mechanism.

[0020] Preferably, the in vitro diagnostic reagent limiting assembly includes a charging and discharging air pipe fixedly connected to the top of the protective box, a charging and discharging air pipe fixedly connected to the upper end of the protective box, a control valve fixedly connected to the outside of the charging and discharging air pipe, and a protective cover detachably connected to the outside of the charging and discharging air pipe. The lower end of the charging and discharging air pipe passes through the protective box and extends into the interior of the airbag body. The upper end of the protective box is provided with an internal thread groove, and the inner wall of the lower end of the protective cover is provided with an external thread. The protective cover is threadedly connected to the inside of the internal thread groove.

[0021] Technical effects and advantages of the present invention:

[0022] Easy data acquisition: By scanning the QR code generated by the device through a PDA or connecting with the device via NFC, you can quickly obtain the cold chain monitoring temperature and humidity information for a specified time period. Compared with traditional paper records, this is more convenient, faster, and less prone to errors.

[0023] Efficient information management: The information obtained by scanning can be connected to the format data of various warehouse management platforms, and the templates can be customized, realizing paperless registration of temperature and humidity monitoring information. It can be linked with the information system to form a complete logistics process record, which is convenient for traceability and management, and improves the efficiency and accuracy of cold chain transportation management.

[0024] Low power consumption and long battery life: Using low-power LoRa wireless technology and lithium battery power supply, combined with low-power solutions such as intelligent sleep mode and smart screen mode, the device can operate for a long time, reducing the frequency of battery replacement, reducing usage costs and maintenance workload;

[0025] Rich and practical functions: The high-precision temperature and humidity acquisition module ensures data accuracy; supports local storage, data retransmission after network disconnection, data feedback, threshold alarms, and other functions, improving data reliability and security; the electronic ink screen displays data in real time for easy viewing at any time; NFC wireless configuration and physical button operation make device configuration and use more convenient; the custom template batch configuration function enhances the device's compatibility with different warehouse management systems;

[0026] High transportation stability: The combined use of the in vitro diagnostic reagent storage component and the in vitro diagnostic reagent limiting component improves the safety and stability of in vitro diagnostic reagents during transportation. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 This is a schematic diagram of the external structure of a device for monitoring and storing temperature and humidity data of cold chain transportation of in vitro diagnostic reagents provided in an embodiment of the present application. Figure 1 ;

[0028] Figure 2 This is a schematic diagram of the external structure of a device for monitoring and storing temperature and humidity data of cold chain transportation of in vitro diagnostic reagents provided in an embodiment of the present application. Figure 2 ;

[0029] Figure 3 This is a schematic diagram of the internal structure of a device for monitoring and storing temperature and humidity data for cold chain transportation of in vitro diagnostic reagents provided in an embodiment of the present application;

[0030] Figure 4 This is a top-sectional view of a device for monitoring and storing temperature and humidity data for cold chain transportation of in vitro diagnostic reagents provided in an embodiment of the present application;

[0031] Figure 5 This is a side cross-sectional view of a device for monitoring and storing temperature and humidity data of cold chain transportation of in vitro diagnostic reagents provided in an embodiment of the present application. Figure 1 ;

[0032] Figure 6 This is a side view of a device for monitoring and storing temperature and humidity data of cold chain transportation of in vitro diagnostic reagents provided in an embodiment of the present application. Figure 2 ;

[0033] Figure 7 This is a schematic structural diagram of an in vitro diagnostic reagent limiting component in a device for monitoring and storing temperature and humidity data for cold chain transportation of in vitro diagnostic reagents provided in an embodiment of the present application;

[0034] Figure 8 This is a schematic structural diagram of an in vitro diagnostic reagent storage component in a device for monitoring and storing temperature and humidity data for cold chain transportation of in vitro diagnostic reagents provided in an embodiment of the present application;

[0035] Figure 9This is a side elevational view of an in vitro diagnostic reagent storage assembly in a device for monitoring and storing temperature and humidity data for cold chain transportation of in vitro diagnostic reagents provided in an embodiment of the present application;

[0036] In the picture:

[0037] 1. Protective box; 2. Hinged door; 3. In vitro diagnostic reagent storage assembly; 4. In vitro diagnostic reagent limit assembly; 5. Rotating shaft; 6. Rotating disk; 7. Reagent placement mechanism; 8. Disk limit assembly; 9. Sliding mounting groove; 10. Sliding mounting block; 11. Reagent placement barrel; 12. Reagent placement groove; 13. Rubber ring; 14. Limit storage groove; 15. First spring; 16. Limit member; 17. Limit adjustment groove; 18. Limit adjustment member; 19. Limit outer cylinder; 20. Limit inner shaft; 21. Limit disk; 22. Limit column; 23. Second spring; 24. Limit groove; 25. Airbag body; 26. Inflating and discharging air pipe; 27. Control valve; 28. Protective cover. DETAILED DESCRIPTION

[0038] The present invention will be described in further detail below with reference to the accompanying drawings and specific embodiments. The embodiments of the present invention are provided for purposes of illustration and description and are not intended to be exhaustive or to limit the invention to the disclosed forms. Many modifications and variations will be apparent to those skilled in the art. The embodiments are chosen and described to better illustrate the principles of the invention and its practical application, and to enable those skilled in the art to understand the invention and design various embodiments with various modifications suitable for specific applications.

[0039] Example 1

[0040] See also Figures 1 to 9 In this embodiment, a device for monitoring and storing temperature and humidity data of cold chain transportation of in vitro diagnostic reagents is provided, comprising a protective box 1, wherein the protective box 1 is a hollow cavity with an opening on one side, a hinged door 2 is hingedly provided on one side of the protective box 1, a sealing gasket is provided between the hinged door 2 and the protective box 1, an in vitro diagnostic reagent storage component 3 is connected to the inner top of the protective box 1, an in vitro diagnostic reagent limiting component 4 is connected to the inner bottom of the protective box 1, and a temperature and humidity acquisition module, a communication module, a data storage module, a display module, a power supply module, a control module, a near-field communication module, a human-computer interaction module, a cooling and heating module, and a dehumidification and humidification module are provided inside the protective box 1;

[0041] The cooling and heating module is used to adjust the temperature inside the protective box 1;

[0042] The dehumidification and humidification module is used to adjust the humidity inside the protective box 1;

[0043] The temperature and humidity acquisition module is used to collect temperature and humidity data in the protective box 1;

[0044] The communication module uses the standard LoRaWAN communication protocol to achieve data transmission;

[0045] Near field communication module, used to achieve rapid data transmission and device configuration modification;

[0046] The human-computer interaction module provides batch configuration of custom templates and can be connected with the data models of various warehouse management systems;

[0047] The data storage module is used to locally store temperature and humidity data;

[0048] The display module is an electronic ink screen, which is arranged on the outside of the protective box 1;

[0049] The power supply module uses lithium batteries to power other modules;

[0050] The control module is used to control the operation of each module.

[0051] The control module serves as the core control unit of the device. It is used to coordinate and control the operation of each module of the device, receive data collected by the temperature and humidity acquisition module, process and analyze the data, and control each module to perform corresponding operations according to preset rules. At the same time, it manages the data storage and reading of the data storage module, and controls the communication module to transmit data.

[0052] The power supply module uses a lithium battery to power the device, providing stable power support for all modules of the device. It uses low-power technology combined with intelligent sleep mode and smart screen mode to extend battery life. Among them, the intelligent sleep mode can be customized to intelligently enable sleep mode at night or during idle time to reduce power consumption; in the smart screen mode, when the data change does not exceed the specified value, the screen stops refreshing and runs in the background, further extending battery life.

[0053] The temperature and humidity acquisition module is equipped with a high-precision temperature and humidity sensor with a temperature acquisition range of -20°C-60°C, an acquisition accuracy of 0.2°C (maximum ±0.4°C), and a resolution of 0.1°C; the humidity acquisition range is 0%-100%RH, an acquisition accuracy of ±2% (maximum ±3%), and a resolution of 0.5%RH. It is used to collect real-time temperature and humidity data in the protective box 1 during the cold chain transportation of in vitro diagnostic reagents and transmit the collected data to the control module;

[0054] The temperature and humidity acquisition module also includes a temperature and humidity calibration unit, which regularly calibrates the high-precision temperature and humidity sensor through a built-in standard temperature and humidity source to ensure the accuracy of the collected data.

[0055] The communication module adopts the standard LoRaWAN communication protocol with strong compatibility. It connects to a compatible standard LoRaWAN gateway through LoRa wireless technology, builds an intelligent communication cloud network with the IoT platform, realizes remote data monitoring and management, uploads the data processed by the control module to the IoT platform, and can also receive instructions issued by the IoT platform to realize remote data monitoring and management.

[0056] The data storage module is used to locally store the data collected by the temperature and humidity acquisition module. It supports network disconnection data retransmission and threshold warning. When the device is in a network disconnection state, the collected data is temporarily stored in the data storage module. After the network is restored, the temporarily stored data is returned to the IoT platform. When the stored data exceeds the preset temperature and humidity threshold, an alarm signal is sent to the control module.

[0057] The data storage module uses a non-volatile memory and is equipped with a data encryption module for encrypting the stored temperature and humidity data to ensure data security.

[0058] The display module uses an electronic ink screen and is connected to the control module to display environmental data in real time.

[0059] The near field communication module is configured with an NFC module, which supports collecting NFC wireless configurations and can complete configuration modifications without disassembling the device. It is used to achieve rapid data transmission and device configuration modifications through near field communication with devices with NFC functions such as PDAs.

[0060] The human-computer interaction module is equipped with physical buttons, which are set on the outside of the protective box 1. Core functions such as data viewing and device configuration can be achieved by simply operating the physical buttons. It provides a custom template batch configuration function and can be connected to various warehouse management system data modes, so that the information content obtained by scanning can be customized according to the warehouse management requirements, realizing paperless registration of temperature and humidity monitoring information.

[0061] The in vitro diagnostic reagent storage component 3 includes a rotating shaft 5 rotatably connected to the inner bottom of the in vitro diagnostic reagent storage component 3, a rotating disk 6 fixedly connected to the upper end of the rotating shaft 5, three groups of reagent placement mechanisms 7 are connected to the upper end of the rotating disk 6, and a disk body limiting component 8 for limiting the rotating disk 6 is connected to the inner bottom of the protective box 1.

[0062] The reagent placement mechanism 7 includes a sliding mounting groove 9 provided at the upper end of the rotating disk 6, a sliding mounting block 10 slidably connected to the inside of the sliding mounting groove 9, and a reagent placement barrel 11 fixedly connected to the upper end of the sliding mounting block 10. The upper end of the reagent placement barrel 11 is provided with multiple groups of reagent placement grooves 12, and the inner walls of the multiple groups of reagent placement grooves 12 are fixedly connected with rubber rings 13. The inner bottoms of the multiple groups of reagent placement grooves 12 are fixedly connected with pressure sensors, which monitor the pressure of the reagent on them in real time.

[0063] Limit receiving grooves 14 are provided on the inner walls of both sides of the sliding mounting groove 9, and first springs 15 are fixedly connected to the inner walls of the two groups of limit receiving grooves 14. One end of the two groups of first springs 15 is fixedly connected to the limit member 16, and one end of the two groups of limit members 16 are slidably connected to the inside of the sliding mounting groove 9. A limit adjustment groove 17 is provided on one side of the two groups of limit receiving grooves 14, and one side of the two groups of limit members 16 is fixedly connected to the limit adjustment member 18. The limit adjustment member 18 is slidably connected to the inside of the limit member 16 to limit the sliding mounting block 10.

[0064] The disk limiting assembly 8 includes a limiting outer cylinder 19 fixedly connected to the inner bottom of the protective box 1, a limiting inner shaft 20 slidably connected to the inner part of the upper end of the limiting outer cylinder 19, a limiting disk 21 fixedly connected to the upper end of the limiting inner shaft 20, and a limiting column 22 fixedly connected to the upper end of the limiting disk 21. A second spring 23 is fixedly connected between the limiting disk 21 and the inner bottom of the protective box 1. Multiple groups of limiting grooves 24 are provided at the lower end of the rotating disk 6. The limiting column 22 is slidably connected to the inside of a group of limiting grooves 24, and the number of limiting grooves 24 is the same as that of the reagent placement mechanism 7.

[0065] The in vitro diagnostic reagent limiting assembly 4 includes a charging and discharging air pipe 26 fixedly connected to the top of the protective box 1, a charging and discharging air pipe 26 fixedly connected to the upper end of the protective box 1, a control valve 27 fixedly connected to the outside of the charging and discharging air pipe 26, and a protective cover 28 detachably connected to the outside of the charging and discharging air pipe 26. The lower end of the charging and discharging air pipe 26 passes through the protective box 1 and extends into the interior of the airbag body 25. An internal thread groove is provided at the upper end of the protective box 1, and an external thread is provided on the inner wall of the lower end of the protective cover 28. The protective cover 28 is threadedly connected to the inside of the internal thread groove. The use of the protective cover protects the charging and discharging air pipe 26.

[0066] The cooling and heating module consists of a semiconductor cooler, a cooling fan, a heating wire, and corresponding control circuitry. The semiconductor cooler operates based on the Peltier effect. When current flows through it, one end cools and the other heats. The current direction and magnitude can be adjusted to achieve cooling or heating functions according to actual temperature requirements. The cooling fan assists in dissipating heat from the hot end of the semiconductor cooler, ensuring efficient cooling and heating. The heating wire activates when the temperature needs to be increased. The control circuit, based on temperature data fed back by a high-precision temperature and humidity sensor, precisely regulates the operating status of the semiconductor cooler and heating wire to maintain the temperature within the storage box within the set range.

[0067] The dehumidification and humidification module consists of a condensing dehumidifier, an ultrasonic humidifier, and a humidity control circuit. The condensing dehumidifier dehumidifies by lowering the air temperature, causing water vapor to condense into droplets and be discharged. The ultrasonic humidifier uses ultrasonic vibrations to atomize water, increasing the air humidity. The humidity control circuit intelligently controls the operation of the condensing dehumidifier and ultrasonic humidifier based on humidity data collected by a high-precision temperature and humidity sensor to ensure that the humidity within the storage box meets the storage requirements for in vitro diagnostic reagents.

[0068] When this solution is used

[0069] First, open the hinged door 2;

[0070] The in vitro diagnostic reagent is placed inside the reagent placement groove 12, and the rubber ring 13 limits the reagent placement groove 12;

[0071] Push the sliding mounting block 10 into the interior of the sliding mounting groove 9, then pull the limit adjustment member 18, the limit adjustment member 18 squeezes the limit receiving groove 14 through the limit member 16 and drives the limit member 16 to move away from the interior of the sliding mounting groove 9, continue to push the sliding mounting block 10, release the pull on the limit adjustment member 18, under the action of the first spring 15, the limit member 16 enters the interior of the sliding mounting groove 9 to limit the sliding mounting block 10, and completes the installation of a set of reagent placement barrels 11;

[0072] Then, the limiting plate 21 is pressed downward, and the limiting plate 21 squeezes the second spring 23, driving the limiting post 22 to be removed from the inside of the limiting groove 24. The rotating disk 6 is rotated, and the pressure on the limiting plate 21 is released. When the next limiting groove 24 moves to the upper end of the limiting post 22, under the action of the second spring 23, the limiting post 22 enters the inside of the limiting groove 24 to limit the rotating disk 6, and the next group of reagent placement barrels 11 are installed. This process is repeated to complete the installation of all reagent placement barrels 11.

[0073] After installation, the protective cover 28 is unscrewed from the inside of the internal thread groove, the control valve 27 is opened, and air is filled into the air bag 25 through the air compressor. The pressure sensor monitors the downward pressure of the in vitro diagnostic reagent in real time. The pressure monitored by the pressure sensor is used to determine the fixation effect of the in vitro diagnostic reagent. The pressure is preset in advance. The preset pressure is such that the air bag has an squeezing effect on the in vitro diagnostic reagent, but the squeezing force does not damage the in vitro diagnostic reagent.

[0074] When the preset pressure is detected, the pressure sensor sends a signal to the controller, which issues an alarm, shuts down the air compressor and the control valve 27, and then installs the protective cover 28 inside the internal thread groove;

[0075] Close the hinged door 2 and fix the hinged door 2 to the opening of the protective box 1 through a mechanical lock (existing technology, which will not be described in detail in this solution) to complete the fixation of the equipment.

[0076] Device Installation

[0077] The temperature and humidity acquisition module, communication module, data storage module, display module, power supply module, control module, near field communication module, human-computer interaction module, cooling and heating module, and dehumidification and humidification module are installed and fixed in appropriate positions in the protective box (1) for cold chain transportation of in vitro diagnostic reagents, ensuring that the installation is firm;

[0078] The outer wall of the protective box (1) is provided with heat dissipation holes for auxiliary heat dissipation, which is common knowledge among people in this field and will not be described in detail in this solution.

[0079] Data collection and processing

[0080] The high-precision temperature and humidity sensor of the temperature and humidity acquisition module collects the temperature and humidity data in the protective box (1) in real time and transmits the collected data to the control module. The control module processes and analyzes the received data to determine whether the data exceeds the preset temperature and humidity threshold. If the threshold is exceeded, the control module controls the data storage module to record the alarm information and can send an alarm notification to relevant personnel through the communication module.

[0081] Data storage and transmission

[0082] The data storage module stores the collected temperature and humidity data locally. When the device is connected to the Internet, the control module controls the communication module to upload the data to the Internet of Things platform to achieve remote data monitoring and management. When the device is disconnected from the Internet, the data storage module temporarily stores the data, and when the network is restored, it automatically transmits the temporarily stored data back to the Internet of Things platform.

[0083] Data viewing and configuration

[0084] Users can operate the human-computer interaction module through physical buttons to realize core functions such as data viewing and device configuration. At the same time, by utilizing the NFC function of the near-field communication module, near-field communication can be carried out with the device through an NFC-enabled device (such as a PDA) to quickly obtain temperature and humidity information for a specified time period. The device can also be configured wirelessly. In addition, through the custom template batch configuration function, the device can be connected to the data mode of various warehouse management systems to realize paperless registration and customized management of temperature and humidity monitoring information.

[0085] The electrical components appearing in this article are all electrically connected to an external main controller, and the main controller can be a conventional known device that controls a computer, etc. The specific implementation method of this disclosure omits the detailed description of known functions and known components. To ensure the compatibility of the equipment, the operating methods used are consistent with the parameters of marketed equipment.

[0086] In the scheme, unless otherwise clearly stipulated and limited, the terms "install", "set", "connect", "fix", "screw" and the like should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integrated connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be the internal connection of two elements or the interaction relationship between two elements. Unless otherwise clearly defined, ordinary technicians in this field can understand the specific meanings of the above terms in this scheme according to the specific circumstances.

[0087] Obviously, the embodiments described are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field and related fields without making creative efforts should fall within the scope of protection of the present invention. Structures, devices, and operating methods not specifically described and explained in the present invention shall be implemented in accordance with conventional means in the field unless otherwise specified or limited.

Claims

1. A device for monitoring and storing temperature and humidity data of cold chain transportation of in vitro diagnostic reagents, comprising a protective box (1), wherein the protective box (1) is provided with a hollow cavity with an opening on one side, a hinged door (2) is hingedly provided on one side of the protective box (1), a sealing gasket is provided between the hinged door (2) and the protective box (1), an in vitro diagnostic reagent storage component (3) is connected to the inner top of the protective box (1), an in vitro diagnostic reagent limiting component (4) is connected to the inner bottom of the protective box (1), and a temperature and humidity acquisition module, a communication module, a data storage module, a display module, a power supply module, a control module, a near-field communication module, a human-computer interaction module, a cooling and heating module, and a dehumidification and humidification module are provided inside the protective box (1); the temperature and humidity acquisition module is used to collect temperature and humidity data inside the protective box (1), the control module serves as the core control unit of the device, and is used to coordinate and control the operation of each module of the device; and the power supply module supplies power to other modules.

2. The device for monitoring and storing temperature and humidity data during cold chain transportation of in vitro diagnostic reagents according to claim 1, characterized in that: The control module receives the data collected by the temperature and humidity acquisition module, processes and analyzes the data, and controls each module to perform corresponding operations according to preset rules. At the same time, it manages the data storage and reading of the data storage module, and controls the communication module to transmit data; the power supply module uses a lithium battery to power the device, and uses low-power technology combined with intelligent sleep mode and smart screen mode to extend battery life.

3. The device for monitoring and storing temperature and humidity data during cold chain transportation of in vitro diagnostic reagents according to claim 1, characterized in that: The temperature and humidity acquisition module is equipped with a high-precision temperature and humidity sensor with a temperature acquisition range of -20°C-60°C, an acquisition accuracy of 0.2°C (maximum ±0.4°C), and a resolution of 0.1°C; a humidity acquisition range of 0%-100%RH, an acquisition accuracy of ±2% (maximum ±3%), and a resolution of 0.5%RH. It is used to collect temperature and humidity data in the protective box (1) during the cold chain transportation of in vitro diagnostic reagents in real time and transmit the collected data to the control module; The temperature and humidity acquisition module also includes a temperature and humidity calibration unit, which regularly calibrates the high-precision temperature and humidity sensor through a built-in standard temperature and humidity source to ensure the accuracy of the collected data.

4. The device for monitoring and storing temperature and humidity data during cold chain transportation of in vitro diagnostic reagents according to claim 1, characterized in that: The communication module adopts the standard LoRaWAN communication protocol, connects to a compatible standard LoRaWAN gateway through LoRa wireless technology, and builds an intelligent communication cloud network with the Internet of Things platform to achieve remote data monitoring and management; The data storage module is used to locally store data collected by the temperature and humidity collection module, and supports the network disconnection data retransmission function and threshold warning. When the device is in a network disconnection state, the collected data is temporarily stored in the data storage module, and after the network is restored, the temporarily stored data is transmitted back to the Internet of Things platform; when the stored data exceeds the preset temperature and humidity threshold, an alarm signal is sent to the control module; the data storage module adopts a non-volatile memory and is provided with a data encryption module for encrypting the stored temperature and humidity data to ensure data security; the display module adopts an electronic ink screen, and the electronic ink screen is arranged on the outside of the protective box (1) and connected to the control module.

5. The device for monitoring and storing temperature and humidity data during cold chain transportation of in vitro diagnostic reagents according to claim 1, characterized in that: The near field communication module is configured with an NFC module to support the collection of NFC wireless configurations for rapid data transmission and device configuration modification; The human-computer interaction module is provided with physical buttons and is arranged on the outside of the protective box (1), providing a custom template batch configuration function and being able to interface with the data modes of various warehouse management systems; The cooling and heating module is used to adjust the temperature inside the protective box (1), and is composed of a semiconductor cooling sheet, a cooling fan, a heating wire and a corresponding control circuit; The dehumidification and humidification module is used to adjust the humidity inside the protection box (1), and is composed of a condensing dehumidifier, an ultrasonic humidifier and a humidity control circuit.

6. The device for monitoring and storing temperature and humidity data during cold chain transportation of in vitro diagnostic reagents according to claim 1, characterized in that: The in vitro diagnostic reagent storage assembly (3) comprises a rotating shaft (5) rotatably connected to the inner bottom of the in vitro diagnostic reagent storage assembly (3), a rotating disk (6) fixedly connected to the upper end of the rotating shaft (5), three groups of reagent placement mechanisms (7) connected to the upper end of the rotating disk (6), and a disk body limiting assembly (8) for limiting the rotating disk (6) connected to the inner bottom of the protective box (1).

7. The device for monitoring and storing temperature and humidity data during cold chain transportation of in vitro diagnostic reagents according to claim 6, characterized in that: The reagent placement mechanism (7) comprises a sliding mounting groove (9) provided at the upper end of the rotating disk (6), a sliding mounting block (10) slidably connected to the interior of the sliding mounting groove (9), and a reagent placement barrel (11) fixedly connected to the upper end of the sliding mounting block (10). The upper end of the reagent placement barrel (11) is provided with multiple groups of reagent placement grooves (12), the inner walls of the multiple groups of reagent placement grooves (12) are fixedly connected with rubber rings (13), the inner bottoms of the multiple groups of reagent placement grooves (12) are fixedly connected with pressure sensors, and the inner walls on both sides of the sliding mounting groove (9) are fixed with pressure sensors. A limit receiving groove (14) is provided, and a first spring (15) is fixedly connected to the inner wall of the two groups of the limit receiving grooves (14), one end of the two groups of the first springs (15) is fixedly connected to the limit member (16), one end of the two groups of the limit members (16) is slidably connected to the inside of the sliding installation groove (9), and a limit adjustment groove (17) is provided on one side of the two groups of the limit receiving grooves (14), and a limit adjustment member (18) is fixedly connected to one side of the two groups of the limit members (16), and the limit adjustment member (18) is slidably connected to the inside of the limit member (16).

8. The device for monitoring and storing temperature and humidity data during cold chain transportation of in vitro diagnostic reagents according to claim 6, characterized in that: The disk limiting assembly (8) includes a limiting outer cylinder (19) fixedly connected to the inner bottom of the protective box (1), a limiting inner shaft (20) slidably connected to the inner portion of the upper end of the limiting outer cylinder (19), a limiting disk (21) fixedly connected to the upper end of the limiting inner shaft (20), and a limiting column (22) fixedly connected to the upper end of the limiting disk (21), and a second spring (23) fixedly connected between the limiting disk (21) and the inner bottom of the protective box (1). The lower end of the rotating disk (6) is provided with multiple groups of limiting grooves (24), and the limiting column (22) is slidably connected to the inside of a group of the limiting grooves (24), and the number of the limiting grooves (24) is the same as that of the reagent placement mechanism (7).

9. The device for monitoring and storing temperature and humidity data during cold chain transportation of in vitro diagnostic reagents according to claim 1, characterized in that: The in vitro diagnostic reagent limiting assembly (4) includes a charging and discharging air pipe (26) fixedly connected to the top of the protective box (1), a charging and discharging air pipe (26) fixedly connected to the upper end of the protective box (1), a control valve (27) fixedly connected to the outside of the charging and discharging air pipe (26), and a protective cover (28) detachably connected to the outside of the charging and discharging air pipe (26). The lower end of the charging and discharging air pipe (26) passes through the protective box (1) and extends into the interior of the airbag body (25). The upper end of the protective box (1) is provided with an internal thread groove, and the inner wall of the lower end of the protective cover (28) is provided with an external thread. The protective cover (28) is threadedly connected to the inside of the internal thread groove.

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