Noctilucent kinesio bandage as well as preparation method and application thereof
By combining nanomaterials and thermosensitive polymers, a luminescent kinesiology bandage was prepared, which solved the problems of limited antibacterial properties, lack of reusability and real-time monitoring, and realized the reusability of the bandage and real-time monitoring of muscle strain.
Patent Information
- Application Number
- CN202510801035.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-16
- Publication Date
- 2025-10-28
AI Technical Summary
Existing Kinesiology bandages have limited antibacterial properties, lack of reusability and lack of real-time monitoring function.
A bioluminescent dermal patch was developed by combining nanomaterials and thermosensitive polymers, integrating antibacterial, thermosensitive, and luminescent functions. The patch consists of a substrate, a thermosensitive adhesive layer, and a luminescent layer. The substrate is composed of polyester fiber, nano-silver fiber, and nano-titanium dioxide fiber. The thermosensitive adhesive layer is composed of poly(N-isopropylacrylamide) copolymer and modified nano-silica. The luminescent layer is composed of rare earth carbon quantum dots and poly(N-isopropylacrylamide) copolymer.
It achieves the reusability of bandages, reduces skin sensitivity through the antibacterial effect of nano-silver fibers, provides ultraviolet shielding with titanium dioxide, facilitates the separation of the temperature-sensitive adhesive layer, and provides intuitive data support for muscle strain through the temperature monitoring of the luminescent layer.
Smart Images
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Abstract
Description
Technical Field
[0001] This invention relates to the field of kinesiology technology, specifically to a luminous kinesiology bandage, its preparation method, and its application. Background Technology
[0002] Existing kinesiology tape bandages consist of waterproof elastic cotton fabric, acrylic hypoallergenic adhesive, and hydrophilic backing paper. After peeling, the adhesive layer easily retains sebum or dust, leading to a significant decrease in adhesion. Most are designed for single use. Furthermore, repeated stretching of the waterproof elastic cotton fabric can cause fabric deformation and a decrease in support. Functionally, existing kinesiology tape bandages primarily improve muscle function through mechanical support, but they have the following drawbacks: 1. Limited antibacterial properties: Sweat easily breeds bacteria, and traditional patches lack a long-lasting antibacterial mechanism; Second, lack of reusability: the data is collected from a single design, resulting in poor reusability. Third, lack of real-time monitoring: It is impossible to intuitively reflect muscle status or temperature changes.
[0003] Based on the monitoring of the above data, a luminous kinesiology patch bandage, its preparation method, and its application are proposed. Through the composite design of nanomaterials and thermosensitive polymers, it integrates antibacterial, thermosensitive, and luminous functions and has good reusability. Summary of the Invention
[0004] To address the shortcomings of existing technologies, this invention provides a luminescent kinesiology bandage, its preparation method, and its application, solving the problems of limited antibacterial properties, lack of reusability, and lack of real-time monitoring of existing kinesiology bandages.
[0005] To achieve the above objectives, the present invention provides the following technical solution: a luminous skin-perfecting bandage, comprising: The substrate material comprises, by weight, 65-75 parts of polyester fiber, 18-22 parts of nano silver fiber, and 6-14 parts of nano titanium dioxide fiber. A temperature-sensitive adhesive layer is adhered to one side of a substrate. The raw materials of the temperature-sensitive adhesive layer include, by weight, 10 parts of poly(N-isopropylacrylamide) copolymer and 7-15 parts of modified nano-silica. A luminescent layer is adhered to the other side of a substrate. The luminescent layer includes thermochromic luminescent dots, wherein the thermochromic luminescent dot raw materials include, by weight: 1-3 parts rare earth carbon quantum dots and 7-9 parts poly(N-isopropylacrylamide) copolymer.
[0006] The present invention is further configured such that the thickness ratio of the substrate, the temperature-sensitive adhesive layer and the luminescent layer is 3-5:1-2:0.5-1.
[0007] The present invention is further configured such that: the diameter of the polyester fiber is 8.9-10.3 μm, the diameter of the nano-silver fiber is 5-10 nm, and the diameter of the nano-titanium dioxide fiber is 20-30 nm.
[0008] The present invention is further configured such that: the rare earth carbon quantum dot raw material comprises, by molar ratio: rare earth nitrate: carbon source = 10: 5-12; The rare earth nitrate is europium nitrate; The carbon source is citric acid.
[0009] The present invention is further configured such that the poly(N-isopropylacrylamide) copolymer raw material includes N-isopropylacrylamide and acrylic acid, wherein the molar ratio of N-isopropylacrylamide to acrylic acid is 7-9:1-3. By adjusting the molar ratio, the low critical solution temperature can be controlled. For example, when the molar ratio is 9:1, the low critical solution temperature is 37.5℃-39.5℃, and when the molar ratio is 4:1, the low critical solution temperature is 40℃-42℃.
[0010] This invention also discloses a method for preparing a luminous dermal patch, comprising the following steps: A1. Polyester fiber was plasma surface treated with 80W power for 60s, and nano-silver fiber and nano-titanium dioxide fiber were ultrasonically dispersed for 30min with ultrasonic power of 200W. A2. A template agent is added to polyester fiber, nano silver fiber and nano titanium dioxide fiber, and a crude substrate is obtained by electrospinning. The template is then removed by thermal phase separation, and a porous substrate is obtained after cleaning and drying. A3. Apply the temperature-sensitive adhesive layer to one side of the porous substrate; A4. Apply thermochromic luminescent dots to the other side of the porous substrate to complete the preparation of the luminescent skin-perfecting bandage.
[0011] The present invention is further configured such that: the method of applying the temperature-sensitive adhesive layer to one side of the porous substrate in step A3 includes: A31. Aminopropyltriethoxysilane was used to modify nano-silica with a grafting density ≥0.5 μmol / m 2 The modified nano-silica was obtained by centrifugation and washing at 4000 rpm for 15 min and then dispersed in anhydrous ethanol. A32. Disperse poly(N-isopropylacrylamide) copolymer and modified nano-silica in a dimethylformamide / water mixed solvent, and sonicate for 30 min to obtain the coating agent; A33. Spin-coat the agent to be sprayed onto one side of the porous substrate at 1500 rpm, and vacuum dry at 60°C for 2 hours. During the process, spray at 365 nm and 5 J / cm. 2 Perform ultraviolet cross-linking.
[0012] The present invention is further configured such that the method of applying thermochromic luminescent dots to the other side of the porous substrate in A4 includes: A41. Rare earth nitrates and carbon sources are added to a microwave reactor, heated with microwaves at 800W for 5 minutes, and then the pH is adjusted to 7 to obtain rare earth carbon quantum dots. A42. Rare earth carbon quantum dots are added to poly(N-isopropylacrylamide) copolymer, PVP binder is added, and spin-coated at 2000 rpm onto the other side of the porous substrate to obtain thermochromic luminescent dots.
[0013] The present invention is further configured such that the processing method of the poly-N-isopropylacrylamide copolymer includes: N-isopropylacrylamide and acrylic acid were weighed in a molar ratio of 7-9:1-3. The reaction was initiated with ammonium persulfate and carried out at 65°C for 8 hours. The mixture was then dialyzed for 48 hours using a dialysis bag with a molecular weight cutoff of 14 kDa. The resulting poly(N-isopropylacrylamide) copolymer was obtained by freeze drying, with a quantum efficiency greater than 45%.
[0014] The present invention also discloses the application of the luminous kinesiology bandage in joint protection, body surface temperature sensing and muscle strain detection for athletes.
[0015] This invention provides a luminescent kinesiology tape bandage, its preparation method, and its applications. It offers the following advantages: The invention uses a porous substrate to match muscle stretching and deformation, reducing the risk of sports injuries; it utilizes nano-silver fibers to increase antibacterial activity, reducing skin sensitivity caused by prolonged application and providing reliable support for bandage reuse; combined with titanium dioxide to shield ultraviolet rays, and with the assistance of a temperature-sensitive adhesive layer, it achieves convenient separation between the bandage and the skin, providing reliable adhesion support for bandage reuse; and through the luminescent layer, it can emit light of different intensities according to skin surface temperature, providing intuitive and reliable data support for sports-induced muscle strains. Detailed Implementation
[0016] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0017] The embodiments of the present invention provide the following technical solutions: Example 1: A luminous dermal patch bandage, comprising a substrate, a temperature-sensitive adhesive layer, and a luminous layer. The temperature-sensitive adhesive layer is adhered to one side of the substrate, and the luminous layer is adhered to the other side of the substrate. The thicknesses of the substrate, the temperature-sensitive adhesive layer, and the luminous layer are 0.5mm, 0.2mm, and 0.08mm, respectively. The luminous layer includes temperature-changing luminous dots distributed on the other side of the substrate, and the pattern can be designed as needed.
[0018] To ensure the elastic modulus of the bandage and adapt to muscle stretching, the substrate adopts a three-dimensional porous structure design. Its raw materials, by weight, include: 65 parts polyester fiber, 18 parts silver nanofiber, and 6 parts titanium dioxide nanofiber. The polyester fiber has a diameter of 8.9 μm, the silver nanofiber has a diameter of 5 nm, and the titanium dioxide nanofiber has a diameter of 20 nm. The preparation method of this three-dimensional porous substrate includes the following steps: A1. Polyester fiber was plasma surface treated with 80W power for 60s, and nano-silver fiber and nano-titanium dioxide fiber were ultrasonically dispersed for 30min with ultrasonic power of 200W. A2. Polyethylene glycol template agent is added to polyester fiber, nano silver fiber and nano titanium dioxide fiber. The mass ratio of polyethylene glycol is 12% of the total fiber mass. A crude substrate is obtained by electrospinning. The process parameters include: voltage 18kV, receiving distance 15cm and spinning rate 0.8ml / h. Template removal via thermally induced phase separation: The crude substrate was heated to 60℃ at a heating rate of 2℃ / min and held at that temperature for 2 hours. The substrate was then ultrasonically cleaned three times with anhydrous ethanol to remove residual template agent, and then vacuum dried at 60°C for 4 hours to obtain a porous substrate.
[0019] To facilitate easy separation of the temperature-sensitive adhesive layer from the skin, the raw materials for the temperature-sensitive adhesive layer include, by weight: 10 parts poly(N-isopropylacrylamide) copolymer and 7 parts modified nano-silica. The preparation method of the temperature-sensitive adhesive layer includes: A31. Amino-modified 20 nm silica nanoparticles with a specific surface area of 450 m² / g were modified with 3-aminopropyltriethoxysilane, with a grafting density ≥0.5 μmol / m². 2 The modified nano-silica was obtained by centrifugation and washing at 4000 rpm for 15 min and then dispersed in anhydrous ethanol. A32. Disperse poly(N-isopropylacrylamide) copolymer and modified nano-silica in a dimethylformamide / water mixed solvent, and sonicate for 30 min to obtain the coating agent; A33. Spin-coat the agent to be sprayed onto one side of the porous substrate at 1500 rpm, and vacuum dry at 60°C for 2 hours. During the process, spray at 365 nm and 5 J / cm. 2Perform ultraviolet cross-linking.
[0020] To further explain, the raw materials for the poly(N-isopropylacrylamide) copolymer include N-isopropylacrylamide and acrylic acid, with a molar ratio of N-isopropylacrylamide to acrylic acid of 9:1.
[0021] The processing methods for poly(N-isopropylacrylamide) copolymers include: N-Isopropylacrylamide and acrylic acid were mixed, and the mixture was initiated by ammonium persulfate. After reacting at 65°C for 8 hours, the mixture was dialyzed for 48 hours using a dialysis bag with a molecular weight cutoff of 14 kDa. The resulting poly(N-isopropylacrylamide) copolymer was obtained by freeze drying, with a quantum efficiency greater than 45%.
[0022] To achieve a direct perception of muscle stretching during exercise by incorporating skin temperature, the thermochromic luminescent material comprises, by weight: 1 part rare earth carbon quantum dots and 9 parts poly(N-isopropylacrylamide) copolymer. The preparation method of the thermochromic luminescent material includes: A41. Rare earth nitrates and carbon sources are added to a microwave reactor, heated with microwaves at 800W for 5 minutes, and then the pH is adjusted to 7 to obtain rare earth carbon quantum dots. A42. Rare earth carbon quantum dots are added to poly(N-isopropylacrylamide) copolymer, PVP binder is added, and spin-coated at 2000 rpm onto the other side of the porous substrate to obtain thermochromic luminescent dots.
[0023] The test results of the substrate, temperature-sensitive adhesive layer, and phosphorescent layer in this embodiment are shown in Table 1: Example 2: To analyze the effect of different fiber ratios in the substrate on the porosity, antibacterial rate, UV protection factor, and elastic modulus of the bandage, this example differs from Example 1 in that: The thicknesses of the substrate, the temperature-sensitive adhesive layer, and the luminescent layer are 0.3mm, 0.1mm, and 0.1mm, respectively. The base material comprises, by weight, 70 parts polyester fiber, 20 parts nano silver fiber, and 10 parts nano titanium dioxide fiber, wherein the diameter of the polyester fiber is 10.3 μm, the diameter of the nano silver fiber is 10 nm, and the diameter of the nano titanium dioxide fiber is 30 nm. The molar ratio of N-isopropylacrylamide to acrylic acid is 4:1.
[0024] The test results of the substrate performance in this embodiment are shown in Table 2: In this embodiment, the increased content and diameter of the nano-silver fibers lead to an increased specific surface area and thus an increased release of silver ions, thereby improving the antibacterial rate. The increased content and diameter of the nano-titanium dioxide fibers form a denser photocatalytic network, improving the UV protection effect. The increased diameter of the polyester fibers enhances fiber rigidity. Although the porosity decreases, the elastic modulus is improved, achieving a balance between rigidity and breathability. As can be seen from Tables 1 and 2, compared with Example 1, the porosity decreases slightly, but the antibacterial rate, UV protection effect, and elastic modulus all show an upward trend. Considering the elastic modulus, the preparation of the substrate components is preferred in Example 2.
[0025] Example 3: To analyze the effect of different polymer and nanoparticle ratios in the temperature-sensitive adhesive layer on adhesion strength and peel strength, this example differs from Example 1 in that: The thicknesses of the substrate, the temperature-sensitive adhesive layer, and the luminescent layer are 0.4mm, 0.1mm, and 0.05mm, respectively. The temperature-sensitive adhesive layer raw materials include, by weight: 10 parts of poly(N-isopropylacrylamide) copolymer and 10 parts of modified nano-silica; The molar ratio of N-isopropylacrylamide to acrylic acid is 9:1. The performance test results of the temperature-sensitive adhesive layer in this embodiment are shown in Table 3. The increased content of modified nano-silica leads to denser physical cross-linking points, which increases the peel strength. However, the excessive nanoparticles hinder the movement of polymer chain segments, resulting in a decrease in adhesion strength. As shown in Tables 1 and 3, compared with Example 1, the adhesion strength decreases while the peel strength increases. Considering the stability of the bandage and the ease of removal, the preparation of the substrate components is preferably carried out in Example 1.
[0026] Example 4: To analyze the effect of different quantum dot and polymer ratios in the luminescent layer on luminescence intensity and temperature response range, this example differs from Example 1 in that: The thermochromic luminescent material comprises, by weight: 2 parts rare earth carbon quantum dots and 8 parts poly(N-isopropylacrylamide copolymer); The molar ratio of N-isopropylacrylamide to acrylic acid is 7:3.
[0027] The performance test results of the luminescent layer in this embodiment are shown in Table 4: In this embodiment, the concentration of rare earth carbon quantum dots exceeds the oxygen quenching threshold, resulting in a concentration quenching effect and a slight decrease in luminescence intensity. As can be seen from Tables 1 and 4, the luminescence intensity decreases compared to Example 1. Considering the luminescence intensity, the preparation of the substrate components is preferred in Example 1.
[0028] Simulation Experiment A luminous dermal patch was prepared with a substrate thickness of 0.5 mm, a temperature-sensitive adhesive layer of 0.2 mm, and a luminescent layer of 0.08 mm, according to the following component ratio: The base material comprises, by weight: 70 parts polyester fiber, 20 parts nano silver fiber, and 10 parts nano titanium dioxide fiber; the temperature-sensitive adhesive layer comprises, by weight: 10 parts poly(N-isopropylacrylamide) copolymer and 7 parts modified nano silica; the luminescent dot material comprises, by weight: 1 part rare earth carbon quantum dots and 9 parts poly(N-isopropylacrylamide) copolymer, and the molar ratio of N-isopropylacrylamide to acrylic acid is 9:1.
[0029] A number of luminescent kinesiology tapes were provided to 60 night runners, 30 men and 30 women. After wearing the luminescent kinesiology tapes provided by this invention, light intensity data generated during high-intensity night runs were collected. After processing the light intensity data and duration, and combining it with the runners' sensory feedback at the application site, it was found that muscle damage occurred after the light intensity data reached a certain level and lasted for a certain duration. Based on this, it can be determined that after wearing the luminescent kinesiology tapes, by monitoring the light intensity and duration emitted by the tapes, combined with the runners' subjective feelings, and establishing individual profiles, the occurrence of muscle damage can be predicted through the analysis of the light intensity and duration emitted by the tapes.
[0030] In summary, this invention not only has reusability, but also allows for complete detachment from the skin after use. Furthermore, the introduction of a bactericidal effect provides health protection for the reusability and long-term use of the bandage. By introducing luminous dots, not only can the appearance be improved by limiting the range of the luminous dots, but different luminous displays can also be made according to the skin temperature of the athlete, providing intuitive data support for muscle strains.
[0031] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.
[0032] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A luminous dermal patch bandage, characterized in that: include: The substrate material comprises, by weight, 65-75 parts of polyester fiber, 18-22 parts of nano silver fiber, and 6-14 parts of nano titanium dioxide fiber. A temperature-sensitive adhesive layer is adhered to one side of a substrate. The raw materials of the temperature-sensitive adhesive layer include, by weight, 10 parts of poly(N-isopropylacrylamide) copolymer and 7-15 parts of modified nano-silica. A luminescent layer is adhered to the other side of a substrate. The luminescent layer includes thermochromic luminescent dots, wherein the thermochromic luminescent dot raw materials include, by weight: 1-3 parts rare earth carbon quantum dots and 7-9 parts poly(N-isopropylacrylamide) copolymer.
2. The luminous dermal patch bandage according to claim 1, characterized in that: The thickness ratio of the substrate, the temperature-sensitive adhesive layer, and the luminescent layer includes: 3-5:1-2:0.5-1.
3. The luminous dermal patch bandage according to claim 1, characterized in that: The polyester fiber has a diameter of 8.9-10.3 μm, the nano-silver fiber has a diameter of 5-10 nm, and the nano-titanium dioxide fiber has a diameter of 20-30 nm.
4. The luminous dermal patch bandage according to claim 1, characterized in that: The rare earth carbon quantum dot raw material comprises, by molar ratio: rare earth nitrate: carbon source = 10:5-12; The rare earth nitrate is europium nitrate; The carbon source is citric acid.
5. The luminous dermal patch bandage according to claim 1, characterized in that: The raw material for the poly(N-isopropylacrylamide) copolymer includes N-isopropylacrylamide and acrylic acid, wherein the molar ratio of N-isopropylacrylamide to acrylic acid is 7-9:1-3.
6. A method for preparing a luminous dermal patch according to any one of claims 1-5, characterized in that: Includes the following steps: A1. Polyester fiber was plasma surface treated with 80W power for 60s, and nano-silver fiber and nano-titanium dioxide fiber were ultrasonically dispersed for 30min with ultrasonic power of 200W. A2. A template agent is added to polyester fiber, nano silver fiber and nano titanium dioxide fiber, and a crude substrate is obtained by electrospinning. The template is then removed by thermal phase separation, and a porous substrate is obtained after cleaning and drying. A3. Apply the temperature-sensitive adhesive layer to one side of the porous substrate; A4. Apply thermochromic luminescent dots to the other side of the porous substrate to complete the preparation of the luminescent skin-perfecting bandage.
7. The method for preparing a luminous dermal patch bandage according to claim 6, characterized in that: The method of applying the temperature-sensitive adhesive layer to one side of the porous substrate in A3 includes: A31. Aminopropyltriethoxysilane was used to modify nano-silica with a grafting density ≥0.5 μmol / m 2 The modified nano-silica was obtained by centrifugation and washing at 4000 rpm for 15 min and then dispersed in anhydrous ethanol. A32. Disperse poly(N-isopropylacrylamide) copolymer and modified nano-silica in a dimethylformamide / water mixed solvent, and sonicate for 30 min to obtain the coating agent; A33. Spin-coat the agent to be sprayed onto one side of the porous substrate at 1500 rpm, and vacuum dry at 60°C for 2 hours. During the process, spray at 365 nm and 5 J / cm. 2 Perform ultraviolet cross-linking.
8. The method for preparing a luminous dermal patch bandage according to claim 6, characterized in that: The method of applying thermochromic luminescent dots to the other side of the porous substrate in A4 includes: A41. Rare earth nitrates and carbon sources are added to a microwave reactor, heated with microwaves at 800W for 5 minutes, and then the pH is adjusted to 7 to obtain rare earth carbon quantum dots. A42. Rare earth carbon quantum dots are added to poly(N-isopropylacrylamide) copolymer, PVP binder is added, and spin-coated at 2000 rpm onto the other side of the porous substrate to obtain thermochromic luminescent dots.
9. The method for preparing a luminous dermal patch bandage according to claim 7, characterized in that: The processing methods for the poly-N-isopropylacrylamide copolymer include: N-isopropylacrylamide and acrylic acid were weighed in a molar ratio of 7-9:1-3. The reaction was initiated with ammonium persulfate and carried out at 65°C for 8 hours. The mixture was then dialyzed for 48 hours using a dialysis bag with a molecular weight cutoff of 14 kDa. The resulting poly(N-isopropylacrylamide) copolymer was obtained by freeze drying, with a quantum efficiency greater than 45%.
10. An application of a luminous dermal patch bandage, characterized in that: The application of this luminescent kinesiology tape in joint protection, body surface temperature sensing, and muscle strain detection for athletes.