A kit for acute kidney injury detection

Abstract

A kit for acute kidney injury detection belongs to the technical field of kidney injury detection. In order to solve the problems of complicated steps in batch detection of multiple patients, continuous exposure of reagents by manual operation, and safety hazards caused by possible pathogens in blood and urine samples, the application comprises a main box and a replacement mechanism. The replacement mechanism is arranged in the middle of the inner side of the main box. The replacement mechanism can complete the seamless connection of separation, replacement and next detection preparation after detection through one-step operation. Especially in batch detection, the operation is less troublesome, the problems of errors and mistakes caused by continuous manual operation are avoided, the risk of manual operation on exposed reagents is greatly reduced, the risk of infection caused by excessive contact or detection of exposed reagents is avoided, and the detection operation is safer.

Description

Technical Field

[0001] This invention relates to the field of kidney injury detection technology, specifically a kit for detecting acute kidney injury. Background Technology

[0002] Acute kidney injury is a common clinical syndrome, mainly characterized by a rapid decline in kidney function and the accumulation of metabolic waste. Its traditional diagnosis relies on parameters such as serum creatinine and urine. The patient's condition is determined by detecting the serum creatinine index in the patient's blood and the biochemical parameters in the urine. However, there are two existing detection methods: one is reagent kit detection, and the other is conventional medical equipment detection. Using reagent kit detection is currently the simplest and fastest detection method.

[0003] Current acute kidney injury detection kits often involve direct exposure of test strips or slabs. After one set of tests is completed, waste reagents need to be manually discarded, and new reagent packaging needs to be opened before the second set of tests can be performed. This process is quite cumbersome when testing multiple patients in batches. Furthermore, the constant contact with exposed reagents poses a safety risk, as blood and urine samples may carry pathogens.

[0004] To address the above issues, a kit for detecting acute kidney injury is proposed. Summary of the Invention

[0005] The purpose of this invention is to provide a reagent kit for the detection of acute kidney injury. Using this device, the problem of the above-mentioned direct exposure of test strips or test plates for detection is solved. When testing multiple patients in batches, the steps are cumbersome, and there are certain safety hazards due to the continuous manual contact with the exposed reagents and the possibility of pathogens in the blood and urine samples.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a reagent kit for detecting acute kidney injury, comprising a main body box and a replacement mechanism. The replacement mechanism for automatic detection and replacement is disposed in the inner middle of the main body box. The replacement mechanism includes a rotating disk, a rotating shaft, a first gear, a first fixed toothed plate, a connecting belt, a mating gear, a receiving seat, and a test reagent plate. The rotating shaft is installed in the middle of the upper and lower ends of the rotating disk, and the first gear is rotatably installed on both sides inside the rotating disk. The first fixed toothed plate meshes with the outside of the first gear. A connecting belt is connected to one side below the first gear, and a mating gear is installed on the other side of the connecting belt. A receiving seat is installed in the middle of the front end of the mating gear, and a test reagent plate is disposed in the middle of the surface of the receiving seat.

[0007] The lower surface of the rotating disk is fixed with two second fixed toothed plates on both sides, and a second gear meshes with the outer side of the second fixed toothed plates. An intermittent gear is provided on the rear side of the second gear, and a movable toothed rod is meshed with one side of the intermittent gear. A fixed sleeve is provided on the outer rear side of the movable toothed rod, and a compression spring is installed on the inner rear side of the fixed sleeve. A buffer spring is provided on the inner front side of the fixed sleeve. A pulling rod is fixedly connected to one side of the front end of the movable toothed rod, and a push plate is fixed to one side of the rear end of the pulling rod. A stacking rack is provided above the front end of the push plate, and a replacement reagent plate is provided inside the stacking rack.

[0008] Furthermore, the main body box includes a detection box, a mounting base, an observation plate, a detection port, and a sealing cover. The mounting base is fixedly installed on the upper surface of the detection box, and an observation plate is provided in the middle of the front side of the surface of the mounting base. A detection port is provided at the rear end of the surface of the observation plate, and sealing covers are installed on both sides of the upper end of the detection box.

[0009] Furthermore, the rotating disk is rotatably connected to the mounting base via a rotating shaft, and the first fixed toothed plate is fixedly connected to the mounting base. The first gear is driven by a connecting belt and a mating gear, and the mating gear is rotatably connected to the receiving base.

[0010] Furthermore, the second gear is connected to the intermittent gear via a pulley, and the intermittent gear is rotatably connected to the stacking frame. The moving rack is elastically connected to the fixed sleeve via a compression spring and a buffer spring, respectively. One end of the compression spring is fixedly connected to one end of the inside of the fixed sleeve, and one end of the buffer spring is fixedly connected to the other end of the inside of the fixed sleeve. Moreover, the elastic force of the buffer spring is less than that of the compression spring. The front and rear ends of the moving rack are both provided with discs.

[0011] Furthermore, the replacement mechanism is provided with positioning mechanisms for automatic positioning on both sides of its interior. The positioning mechanism includes a fixed plate, a first rotating seat and a first rotating rod. The first rotating seat is fixedly installed on one side of the lower end of the fixed plate, and the first rotating rod is rotatably arranged in the middle of the first rotating seat.

[0012] Furthermore, the positioning mechanism also includes a fixing block, a first support spring, a contact plate, and a pressing rod. A fixing block is fixedly installed on one side of the upper part of the first rotating rod, and a first support spring is installed on one side of the fixing block. The front end of the first support spring is fixedly connected to the surface of the fixing plate. A contact plate is installed on one side of the upper end of the first rotating rod, and a pressing rod is installed below one side of the contact plate. The bottom of the pressing rod is fixedly connected to the inner surface of the rotating disk.

[0013] Furthermore, the positioning mechanism also includes a second rotating seat, a positioning pressure plate, and a second rotating rod. The second rotating seat is installed on one side of the lower end of the first rotating rod, and the positioning pressure plate is installed on the front end of the second rotating seat. The second rotating rod is provided on the upper side of the first rotating rod.

[0014] Furthermore, a recycling mechanism for waste storage is provided on the lower rear side of the replacement mechanism. The recycling mechanism includes a pull-out cover, a pull-out compartment, and a collection compartment. The pull-out compartment is installed at the center of the front end of the pull-out cover, and the collection compartment is installed at the center of the inner side of the pull-out compartment.

[0015] Furthermore, the recycling mechanism also includes a plug-in post and a second support spring. The plug-in post is fixedly installed on the lower sides of the bottom of the collection compartment, and the second support spring is installed on the lower outer side of the plug-in post. The bottom of the second support spring is fixedly connected to the inner surface of the pull-out compartment.

[0016] Furthermore, the recycling mechanism also includes a protrusion, an electrical contact, a lifting rod, and an indicator light. A protrusion is fixed to the lower center of the collection chamber, and an electrical contact is provided on the lower side of the protrusion. The electrical contact is fixedly connected to the pull-out cover. A lifting rod is fixed to the inner center of the collection chamber, and an indicator light is installed on one side of the outer surface of the pull-out cover.

[0017] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0018] 1. This invention, through a replacement mechanism, completes the positional exchange of the front and rear test reagent plates during the 180-degree clockwise rotation of the rotating disk. Simultaneously, it automatically adds replacement reagent plates and automatically separates used test reagent plates. This allows for a seamless transition between separation, replacement, and preparation for the next test in a single operation. Especially in batch testing, such as continuous screening of multiple patients, it reduces operational complexity and avoids the errors and inaccuracies that can easily occur with repeated manual operations. Furthermore, since the test reagent plates and replacement reagent plates are all processed within the rotating disk during testing, separation, and replacement, it significantly reduces the risk of direct manual handling of exposed reagents. This avoids excessive contact with pathogens that may be present in blood and urine samples, or the risk of needle pricks or sample spillage leading to infection due to exposed reagents, making the testing operation simpler and safer.

[0019] 2. The present invention, through a positioning mechanism, ensures the stability of the replacement reagent plate during subsequent rotation, adjustment, detection, and flipping processes. This prevents the replacement reagent plate from moving arbitrarily, causing positional changes or slippage that could affect the accuracy and safety of detection and adjustment. At the same time, it enables the replacement reagent plate to automatically separate, fall, and be retrieved. This improves the stability of the replacement reagent plate adjustment and avoids the inconvenience of manual separation or individual pauses.

[0020] 3. The present invention, through its recycling mechanism, can notify staff that the collection of waste test reagent strips has been completed, allowing staff to pull out the drawer using the pull-out cover and finally remove the collection chamber using the lifting rod to process the test reagent strips. This facilitates one-time processing by staff, avoiding the need for separate disposal of waste reagents and thus reducing work efficiency. Furthermore, the waste reagents enclosed in the drawer chamber also help reduce repeated contact with personnel and the infection and contamination problems caused by reagent exposure. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the overall external three-dimensional structure of the present invention;

[0022] Figure 2 This is a schematic diagram of the unfolded three-dimensional structure of the sealing cap of the present invention;

[0023] Figure 3 This is a bottom-view perspective view of the mounting base of the present invention.

[0024] Figure 4 This is a cross-sectional three-dimensional structural diagram of the rotating disk of the present invention;

[0025] Figure 5 This is a schematic diagram of the three-dimensional structure of the first gear of the present invention;

[0026] Figure 6 This is a cross-sectional three-dimensional structural diagram of the fixing sleeve of the present invention;

[0027] Figure 7 This is a three-dimensional structural diagram of the receiving seat of the present invention;

[0028] Figure 8 This is a three-dimensional structural diagram of the positioning mechanism of the present invention;

[0029] Figure 9 This is a three-dimensional structural diagram of the recycling mechanism of the present invention;

[0030] Figure 10 This is a cross-sectional three-dimensional structural diagram of the collection compartment of the present invention.

[0031] In the diagram: 1. Main body box; 101. Detection box; 102. Mounting base; 103. Observation plate; 104. Detection port; 105. Sealing cover; 2. Replacement mechanism; 201. Rotating disk; 202. Rotating shaft; 203. First gear; 204. First fixed gear plate; 205. Linkage belt; 206. Matching gear; 207. Receiver; 208. Detection reagent plate; 209. Second fixed gear plate; 210. Second gear; 211. Intermittent gear; 212. Moving rack; 213. Fixed sleeve; 214. Compression spring; 215. Pull rod; 216. Push plate; 217. Buffer 218. Stamping spring; 219. Stacking rack; 3. Replacement reagent plate; 3. Positioning mechanism; 301. Fixing plate; 302. First rotating seat; 303. First rotating rod; 304. Fixing block; 305. First support spring; 306. Contact plate; 307. Pressing rod; 308. Second rotating seat; 309. Positioning pressure plate; 310. Second rotating rod; 4. Recycling mechanism; 401. Pull-out cover; 402. Pull-out compartment; 403. Collection compartment; 404. Insertion post; 405. Second support spring; 406. Protrusion; 407. Electrical contact; 408. Lifting rod; 409. Indicator light. Detailed Implementation

[0032] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0033] To address the issue of directly exposed testing using test strips or plates, the process is cumbersome in batch testing of multiple patients. Furthermore, the constant human contact with exposed reagents poses safety risks, especially given that blood and urine samples may carry pathogens. Figures 1-6 As shown, the following preferred technical solutions are provided:

[0034] A reagent kit for detecting acute kidney injury includes a main body box 1 and a replacement mechanism 2. The replacement mechanism 2 for automatic detection and replacement is located in the middle of the inner side of the main body box 1. The main body box 1 includes a detection box 101 located in the middle of the upper part of the main body box 1. A mounting base 102 is fixedly installed on the upper surface of the detection box 101, and an observation plate 103 is provided in the middle of the front side of the surface of the mounting base 102. A detection port 104 is provided at the rear end of the surface of the observation plate 103. Sealing caps 105 are installed on both sides of the upper end of the detection box 101. The observation plate 103 is made of transparent plastic, and the detection port 104 is a drop-in port, which is directly below the sample addition end of the test reagent plate 208.

[0035] The replacement mechanism 2 includes a rotating disk 201 located in the middle of the mounting base 102. A rotating shaft 202 is installed in the middle of the upper and lower ends of the rotating disk 201. A first gear 203 is rotatably installed on both sides inside the rotating disk 201. A first fixed toothed plate 204 meshes with the outside of the first gear 203. A connecting belt 205 is connected to one side below the first gear 203. A mating gear 206 is installed on the other side of the connecting belt 205. A receiving seat 207 is installed in the middle of the front end of the mating gear 206. A test reagent plate 208 is provided in the middle of the surface of the receiving seat 207. The mating gear 206 consists of two sets of vertically meshing bevel gears. The rotational power of the first gear 203 can be transmitted through the connecting belt 205 to drive the receiving seat 207 to rotate. Two sets of test reagent plates 208 are provided on one side of the receiving seat 207, which are existing blood test strips and urine test strips, respectively.

[0036] The lower surface of the rotating disk 201 is fixed with two sides of a second fixed toothed plate 209, and a second gear 210 is meshed on the outer side of the second fixed toothed plate 209. An intermittent gear 211 is provided on the rear side of the second gear 210, and a movable toothed rod 212 is meshed on one side of the intermittent gear 211. A fixed sleeve 213 is provided on the outer rear side of the movable toothed rod 212, and a compression spring 214 is installed on the inner rear side of the fixed sleeve 213. A buffer spring 217 is provided on the inner front side of the fixed sleeve 213. A pulling rod 215 is fixedly connected to one side of the front end of the movable toothed rod 212, and a push plate 216 is fixed on one side of the rear end of the pulling rod 215. A stacking rack 218 is provided above the front end of the push plate 216, and a replacement reagent plate 219 is provided inside the stacking rack 218. The second gear 210 is rotatably mounted on the lower surface of the mounting base 102.

[0037] The rotating disk 201 is rotatably connected to the mounting base 102 via the rotating shaft 202, and the first fixed toothed plate 204 is fixedly connected to the mounting base 102. The first gear 203 is driven by the connecting belt 205 and the mating gear 206, and the mating gear 206 is rotatably connected to the receiving base 207.

[0038] The second gear 210 is connected to the intermittent gear 211 via a pulley, and the intermittent gear 211 is rotatably connected to the stacking frame 218. The moving rack 212 is elastically connected to the fixed sleeve 213 via a compression spring 214 and a buffer spring 217, respectively. One end of the compression spring 214 is fixedly connected to one end of the inside of the fixed sleeve 213, and one end of the buffer spring 217 is fixedly connected to the other end of the inside of the fixed sleeve 213. Moreover, the elastic force of the buffer spring 217 is less than that of the compression spring 214. The front and rear ends of the moving rack 212 are both equipped with discs.

[0039] Through the detection port 104, blood and urine test samples from the external dropper can be vertically dripped into two sets of test reagent plates 208 corresponding to the existing technology principle. The color change of the blood and urine test reagent plates 208 is compared with the existing colorimetric card to detect the condition of kidney damage.

[0040] By rotating the rotating shaft 202 clockwise, the rotating disk 201 rotates clockwise within the mounting base 102. When the rotating disk 201 rotates together with the first gear 203, the first gear 203 on one side will mesh with the fixed first fixed tooth plate 204, causing the first gear 203 to rotate. Subsequently, the first gear 203 will drive the two sets of receiving seats 207 to rotate via the connecting belt 205 and the mating gear 206. When the first gear 203 rotates and separates from the first fixed tooth plate 204, it will have rotated exactly 180 degrees. The receiving seats 207 will also be driven to rotate exactly 180 degrees, allowing the positions of the front and rear sets of receiving seats 207 to be swapped. This moves the front detection to the rear and moves the unused replacement reagent plate 219 from the rear to the front. After the swap, the used test reagent plate 208 will flip downwards, and then the used test reagent plate 208 will fall downwards under its own gravity.

[0041] During the 180-degree clockwise rotation of the rotating disk 201, the second fixed toothed plate 209, driven by the rotating disk 201, causes the second gear 210 to rotate. At this time, the second gear 210, through the synchronous belt pulley, drives the intermittent gear 211 to rotate, causing the intermittent gear 211 to transmit rotational power to the convex toothed plate on the surface of the moving toothed rod 212. This causes the moving toothed rod 212 to move towards the compression spring 214. During the movement of the moving toothed rod 212, the pull rod 215 simultaneously pushes the push plate 216 forward. This moves the push plate 216, located inside and below the stacking rack 218 (i.e., the bottom of the replacement reagent plate 219), out of the stacking rack 218, causing the replacement reagent plate 219 to fall onto the push plate 216. At the front end, when the rotating disk 201 rotates exactly 180 degrees, causing the positions of the front and rear sets of receiving seats 207 to be interchanged, the intermittent gear 211 will just disengage from the moving rack 212. The moving rack 212 will then drive the pulling rod 215 and the push plate 216 to move forward quickly under the rebound action of the compression spring 214. This will cause the push plate 216 to push the replacement reagent plate 219 on the front side forward. The outlet of the replacement reagent plate 219 is directly opposite the upper entrance of the receiving seat 207. At this time, the replacement reagent plate 219 will be ejected into the upper end of the receiving seat 207. The buffer spring 217 can weaken the ejection force of the compression spring 214 and prevent the replacement reagent plate 219 from moving too fast and derailing.

[0042] In this way, during the 180-degree clockwise rotation of the rotating disk 201, the positions of the front and rear test reagent plates 208 are switched, the replacement reagent plate 219 is automatically added, and the used test reagent plate 208 is automatically separated. This allows for a seamless transition between separation, replacement, and preparation for the next test with just one step. Especially in batch testing, such as continuous screening of multiple patients, it reduces the complexity of operations and avoids the errors and mistakes that are prone to occur with repeated manual operations. Furthermore, since the test reagent plate 208 and the replacement reagent plate 219 are all processed within the rotating disk 201 during the testing, separation, and replacement processes, the risk of direct manual handling of exposed reagents is greatly reduced. This avoids the risk of infection from excessive contact with pathogens that may be carried in blood and urine samples, or from exposed reagents that could lead to needle pricks or sample spillage. This makes the testing operation simpler and safer.

[0043] To address the technical problem of reagents easily slipping or even falling off during movement, adjustment, detection, and inversion, thus affecting the stability and safety of the detection, such as... Figure 4 and Figure 5 as well as Figure 7 and Figure 8 As shown, the following preferred technical solutions are provided:

[0044] The replacement mechanism 2 has a positioning mechanism 3 on both sides inside. The positioning mechanism 3 includes a fixing plate 301 fixed to the upper end of the slot on the side wall of the receiving seat 207. A first rotating seat 302 is fixedly installed on one side of the lower end of the fixing plate 301, and a first rotating rod 303 is rotatably arranged in the middle of the first rotating seat 302.

[0045] A fixing block 304 is fixedly installed on one side above the first rotating rod 303, and a first support spring 305 is provided on one side of the fixing block 304. The front end of the first support spring 305 is fixedly connected to the surface of the fixing plate 301. A contact plate 306 is installed on one side of the upper end of the first rotating rod 303, and a pressing rod 307 is provided below one side of the contact plate 306. The bottom of the pressing rod 307 is fixedly connected to the inner surface of the rotating disk 201.

[0046] A second rotating seat 308 is installed on one side of the lower end of the first rotating rod 303, and a positioning pressure plate 309 is installed at the front end of the second rotating seat 308. A second rotating rod 310 is provided on the upper side of the first rotating rod 303.

[0047] The second rotating rods 310 on both sides of the upper placement groove of the receiving seat 207 are pushed by the corresponding first support springs 305, causing the positioning pressure plate 309 corresponding to the second rotating rod 310 to press into the receiving seat 207. When the replacement reagent plate 219 springs into the upper placement groove of the receiving seat 207, the arc edge and the elastic impact cause the replacement reagent plate 219 to press the positioning pressure plate 309 corresponding to the second rotating rod 310. After it is in place, the positioning pressure plate 309 corresponding to the second rotating rod 310 can provide a certain squeezing force on the side of the replacement reagent plate 219. In this way, during the subsequent rotation, adjustment, detection and flipping of the replacement reagent plate 219, the stability of the replacement reagent plate 219 can be guaranteed, and the replacement reagent plate 219 can be prevented from moving at will, causing its position to change or slip, which would affect the accuracy and safety of detection and adjustment.

[0048] After the receiving seat 207 is flipped downwards by 180 degrees, the contact plate 306 corresponding to the first rotating rod 303 will be squeezed by the pressing rod 307, causing the upper end of the first rotating rod 303 to rotate and compress the first support spring 305. This causes the lower end of the first rotating rod 303 to drive the second rotating seat 308 and the positioning pressure plate 309 to move towards the side wall of the replacement reagent plate 219 that is separated from the receiving seat 207. At this time, the replacement reagent plate 219 loses the squeezing force of the positioning pressure plate 309, allowing the replacement reagent plate 219 to fall and be retracted automatically. This improves the stability of the adjustment of the replacement reagent plate 219 and avoids the trouble of manual or separate separation.

[0049] To address the technical problem of increasing operational complexity and safety hazards caused by the need for multiple handling of discarded reagents, such as... Figure 1 and Figure 2 as well as Figure 9 and Figure 10 As shown, the following preferred technical solutions are provided:

[0050] A recycling mechanism 4 for waste storage is provided on the lower rear side of the replacement mechanism 2. The recycling mechanism 4 includes a pull-out cover 401 installed on the lower rear surface of the detection box 101. A pull-out compartment 402 is installed in the middle of the front end of the pull-out cover 401, and a collection compartment 403 is installed in the middle of the inner side of the pull-out compartment 402.

[0051] The bottom of the collection chamber 403 is fixedly provided with plug-in posts 404 on both sides below, and a second support spring 405 is provided on the lower outer side of the plug-in posts 404. The bottom of the second support spring 405 is fixedly connected to the inner surface of the pull-out chamber 402.

[0052] A protrusion 406 is fixed at the lower center of the collection compartment 403, and an electrical contact 407 is provided on the lower side of the protrusion 406. The electrical contact 407 is fixedly connected to the pull-out cover 401. A lifting rod 408 is fixed at the inner center of the collection compartment 403. An indicator light 409 is installed on one side of the outer surface of the pull-out cover 401. The indicator light 409 is powered by a button battery of existing principle installed inside the pull-out cover 401.

[0053] The pull-out compartment 402, located directly below the rear receiving seat 207, allows used test reagent plates 208 to fall into the collection compartment 403 for unified collection. As the number and weight of used test reagent plates 208 collected in the collection compartment 403 increase, the collection compartment 403 will press down on the second support spring 405. When it moves down to a certain extent, it will cause the protrusion 406 to press against the electrical contact 407. The electrical contact 407 is the switch for the indicator light 409. When the electrical contact 407 is activated, the indicator light 409 will turn on. It illuminates when powered on, indicating to staff that the waste test reagent plate 208 has been collected. Staff can then use the pull-out cover 401 to pull out the pull-out compartment 402, and finally use the lifting rod 408 to remove the collection compartment 403 to process the test reagent plate 208. This facilitates one-time processing by staff, avoiding the need for separate disposal of waste reagents, which would affect work efficiency. At the same time, the waste reagents enclosed in the pull-out compartment 402 also help reduce repeated contact with personnel and the infection and contamination problems caused by reagent exposure.

[0054] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also those inherent to such process, method, article, or apparatus.

[0055] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A kit for detecting acute kidney injury, comprising a main body (1) and a replacement mechanism (2), characterized in that: The replacement mechanism (2) for automatic detection and replacement is located in the middle of the inner side of the main body box (1). The replacement mechanism (2) includes a rotating disk (201), a rotating shaft (202), a first gear (203), a first fixed toothed plate (204), a connecting belt (205), a mating gear (206), a receiving seat (207), and a test reagent plate (208). The rotating shaft (202) is installed in the middle of the upper and lower ends of the rotating disk (201), and the first gear (203) is rotatably installed on both sides inside the rotating disk (201). The first fixed toothed plate (204) meshes with the outside of the first gear (203). The connecting belt (205) is connected to one side below the first gear (203), and the mating gear (206) is installed on the other side of the connecting belt (205). The receiving seat (207) is installed in the middle of the front end of the mating gear (206), and the test reagent plate (208) is provided in the middle of the surface of the receiving seat (207). The lower surface of the rotating disk (201) is fixed with two sides of a second fixed toothed plate (209), and a second gear (210) meshes with the outer side of the second fixed toothed plate (209). An intermittent gear (211) is provided on the rear side of the second gear (210), and a moving toothed rod (212) meshes with one side of the intermittent gear (211). A fixed sleeve (213) is provided on the outer rear side of the moving toothed rod (212), and a compression spring (214) is installed on the inner rear side of the fixed sleeve (213). A buffer spring (217) is provided on the inner front side of the fixed sleeve (213). A pulling rod (215) is fixedly connected to one side of the front end of the moving toothed rod (212), and a push plate (216) is fixed on one side of the rear end of the pulling rod (215). A stacking rack (218) is provided above the front end of the push plate (216), and a replacement reagent plate (219) is provided inside the stacking rack (218).

2. The kit for detecting acute kidney injury according to claim 1, characterized in that: The main body box (1) includes a detection box (101), a mounting base (102), an observation plate (103), a detection port (104), and a sealing cover (105). The mounting base (102) is fixedly installed on the upper surface of the detection box (101), and the observation plate (103) is provided in the middle of the front side of the surface of the mounting base (102). The detection port (104) is provided at the rear end of the surface of the observation plate (103), and the sealing cover (105) is installed on both sides of the upper end of the detection box (101).

3. The kit for detecting acute kidney injury according to claim 2, characterized in that: The rotating disk (201) is rotatably connected to the mounting base (102) via the rotating shaft (202), and the first fixed toothed plate (204) is fixedly connected to the mounting base (102). The first gear (203) is driven by the connecting belt (205) and the mating gear (206), and the mating gear (206) is rotatably connected to the receiving seat (207).

4. The kit for detecting acute kidney injury according to claim 1, characterized in that: The second gear (210) is connected to the intermittent gear (211) via a pulley, and the intermittent gear (211) is rotatably connected to the stacking rack (218). The moving rack (212) is elastically connected to the fixed sleeve (213) via a compression spring (214) and a buffer spring (217), respectively. One end of the compression spring (214) is fixedly connected to one end of the inside of the fixed sleeve (213), and one end of the buffer spring (217) is fixedly connected to the other end of the inside of the fixed sleeve (213). Moreover, the elastic force of the buffer spring (217) is less than that of the compression spring (214). The front and rear ends of the moving rack (212) are provided with discs.

5. A kit for detecting acute kidney injury according to claim 1, characterized in that: The replacement mechanism (2) has a positioning mechanism (3) for automatic positioning on both sides inside. The positioning mechanism (3) includes a fixed plate (301), a first rotating seat (302) and a first rotating rod (303). The first rotating seat (302) is fixedly installed on one side of the lower end of the fixed plate (301), and the first rotating rod (303) is rotatably installed in the middle of the first rotating seat (302).

6. A kit for detecting acute kidney injury according to claim 5, characterized in that: The positioning mechanism (3) further includes a fixing block (304), a first support spring (305), a contact plate (306), and a pressing rod (307). A fixing block (304) is fixedly installed on one side above the first rotating rod (303), and a first support spring (305) is installed on one side of the fixing block (304). The front end of the first support spring (305) is fixedly connected to the surface of the fixing plate (301). A contact plate (306) is installed on one side of the upper end of the first rotating rod (303), and a pressing rod (307) is installed below one side of the contact plate (306). The bottom of the pressing rod (307) is fixedly connected to the inner surface of the rotating disk (201).

7. A kit for detecting acute kidney injury according to claim 5, characterized in that: The positioning mechanism (3) further includes a second rotating seat (308), a positioning pressure plate (309), and a second rotating rod (310). The second rotating seat (308) is installed on one side of the lower end of the first rotating rod (303), and the positioning pressure plate (309) is installed at the front end of the second rotating seat (308). The second rotating rod (310) is provided on the upper side of the first rotating rod (303).

8. A kit for detecting acute kidney injury according to claim 1, characterized in that: The replacement mechanism (2) is provided with a recycling mechanism (4) for waste storage at the rear lower side. The recycling mechanism (4) includes a pull-out cover (401), a pull-out compartment (402) and a collection compartment (403). The pull-out compartment (402) is installed at the front middle of the pull-out cover (401), and the collection compartment (403) is installed at the inner middle of the pull-out compartment (402).

9. A kit for detecting acute kidney injury according to claim 8, characterized in that: The recycling mechanism (4) further includes a plug-in post (404) and a second support spring (405). The plug-in post (404) is fixedly installed on the lower sides of the bottom of the collection bin (403), and the second support spring (405) is installed on the lower outside of the plug-in post (404). The bottom of the second support spring (405) is fixedly connected to the inner surface of the pull-out bin (402).

10. A kit for detecting acute kidney injury according to claim 8, characterized in that: The recycling mechanism (4) also includes a protrusion (406), an electrical contact (407), a lifting rod (408), and an indicator light (409). The protrusion (406) is fixed in the lower center of the collection chamber (403), and an electrical contact (407) is provided on the lower side of the protrusion (406). The electrical contact (407) is fixedly connected to the pull-out cover (401). The lifting rod (408) is fixed in the inner center of the collection chamber (403), and an indicator light (409) is installed on one side of the outer surface of the pull-out cover (401).

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