Needle withdrawing zero point self-calibration method of replaceable radio frequency microneedle component

Abstract

The invention discloses a needle withdrawing zero point self-calibration method capable of replacing a radio frequency microneedle component, and belongs to the technical field of radio frequency beauty medical instruments. In order to solve the problem that a needle withdrawing zero point position is difficult to calibrate after a radio frequency microneedle part of a radio frequency operation hand tool of radio frequency equipment at present is replaced, the needle withdrawing zero point self-calibration method comprises the following steps: designing a zero point automatic detection calibration circuit in a hand tool main body provided with the microneedle part; after a conductive foil is pressed on the pinhole end face of the radio frequency microneedle component, a conductive flat plate is formed on the end face; the needle withdrawing zero point self-calibration method is realized by detecting the value of a displacement sensor for recording the position when a radio frequency microneedle is changed from an open circuit to a short circuit when a microneedle head touches a conductive flat plate in the needle withdrawing displacement process. By introducing a skin adsorption judgment function, the accuracy and safety of the microneedle surgery are improved. In the operation process, the adsorption state between the skin and the hand tool is monitored in real time, and it is ensured that the insertion depth and position of the microneedle are accurate and controllable.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of radio frequency cosmetic medical instruments, and particularly relates to a method for self-calibration of a needle-out zero point of a replaceable radio frequency microneedle component. BACKGROUND

[0002] The radio frequency microneedle is a point array type microneedle device widely used in medical and cosmetic fields, which is used to penetrate the microneedle into the subcutaneous dermis layer, control the depth with a precision of 0.1 mm, and release radio frequency energy at the depth. The calibration of the needle-out zero point of the microneedle is of great significance to ensure the accuracy and repeatability of the microneedle. However, in reality, it is difficult to ensure the consistency of the replaceable microneedle component during the production process, and there is a deviation in the needle-out zero point when the microneedle component is installed on the surgical hand tool. Therefore, the accuracy of the depth of the surgical microneedle penetrating into the skin must be ensured after zero point calibration. In the prior art, the calibration process of the needle-out zero point of the radio frequency microneedle is visually calibrated by using a caliper. This process is relatively professional and complicated, and requires a lot of time and manpower, which affects the use efficiency of the microneedle device and the smooth progress of the experiment. Moreover, the current radio frequency microneedle needle-out zero point calibration method is difficult for the operator of the actual device to master. Therefore, it is necessary to develop a method for automatic calibration of the needle-out zero point of the replaceable radio frequency microneedle component to improve the calibration efficiency and accuracy of the microneedle device and reduce the difficulty of using the device. SUMMARY

[0003] In view of the difficulty in calibrating the needle-out zero point position of the radio frequency surgical hand tool of the current radio frequency device after replacing the radio frequency microneedle component, the application provides a method for self-calibration of the needle-out zero point of the replaceable radio frequency microneedle component.

[0004] To solve the above technical problems, the application adopts the following technical scheme:

[0005] A method for self-calibration of the needle-out zero point of the replaceable radio frequency microneedle component, a zero point automatic detection and calibration circuit is designed in the hand tool main body for installing the microneedle component; a conductive foil is pressed against the end face of the needle hole of the radio frequency microneedle component to form a conductive flat plate on the end face; the method for self-calibration of the needle-out zero point is realized by detecting the displacement sensor value when the radio frequency microneedle is triggered to record the position when the radio frequency microneedle changes from open circuit to short circuit when touching the conductive flat plate during the needle-out displacement process.

[0006] Further, the zero point automatic detection and calibration circuit comprises a radio frequency current transformer, a radio frequency current signal conversion circuit, a voltage amplification circuit, a comparator, a 16-bit data latch, a 16-bit zero point data register, and a displacement sensor.

[0007] Further, the radio frequency current transformer is used to collect radio frequency current and realize electrical isolation between high-voltage radio frequency circuit and low-voltage automatic zero-point calibration circuit, so as to ensure that the low-voltage circuit part can work normally without damage; the current variable ratio of the radio frequency current transformer is between 10:1 and 100:1, and the use frequency range meets 200KHz~10MHz.

[0008] Further, the radio frequency current signal conversion circuit adopts a low-offset operational amplifier with a bandwidth higher than 50MHz to convert 200KHz~10MHz radio frequency alternating current into direct current voltage.

[0009] Further, the voltage amplification circuit adopts a high-voltage slew rate operational amplifier to amplify about 100mV voltage to 2V. The zero-point self-calibration radio frequency output power is very low, and in order to ensure that the micro-needle tip is not burned by the conductive foil short circuit, the voltage of the front-stage output of the micro-needle circuit changes about 100mV.

[0010] Further, the comparator adopts a high-speed comparator, and the zero-point calibration threshold voltage is 1.25V. When the output signal of the comparator produces a falling edge, the data of the stored displacement sensor is triggered.

[0011] Further, the 16bit data latch is used for the displacement value of the stored sensor; the 16bit zero-point data register is used for storing the displacement sensor value at the calibrated working displacement zero point, and the data of the data register does not lose after power failure.

[0012] Further, the displacement sensor adopts an absolute linear displacement sensor, which is connected to the displacement advancing mechanism of the micro-needle in structure; the range of the displacement sensor is 15mm, which is greater than the maximum displacement stroke 10mm of the micro-needle, the sensing accuracy is higher than the needle-out accuracy 0.1mm of the device, and 0.05mm is adopted; the linear displacement position feedback of the micro-needle is used.

[0013] Further, the material of the conductive foil used to form the conductive flat plate is aluminum foil; the thickness of the conductive flat plate is between 0.05mm and 0.2mm.

[0014] Further, the radio frequency of the radio frequency micro-needle part is 200KHz~10MHz.

[0015] The frequency and waveform of the radio frequency are completely consistent with the frequency and waveform of the actual working radio frequency of the device, and only the amplitude of the voltage is very small.

[0016] Principle: In the process of upward displacement of the radio frequency microneedle, the microneedle is open circuit when the needle tip does not touch the conductive flat plate, the input voltage of the comparator is much lower than 1.25V, and the output of the comparator is continuously high level; when the needle tip touches the conductive flat plate, the microneedle is short circuit, the input voltage of the comparator is higher than 1.25V, and the output voltage of the comparator reverses to low level immediately, at this time, the falling edge of the level triggers the displacement value of the displacement sensor at this time stored in the data latch.

[0017] Compared with the prior art, the present application has the following advantages:

[0018] By introducing the skin adsorption determination function, the accuracy and safety of the microneedle operation are improved. In the operation process, the adsorption state between the skin and the hand tool is monitored in real time, so that the depth and position of the microneedle insertion are accurately controllable. BRIEF DESCRIPTION OF DRAWINGS

[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.

[0020] Figure 1 The front end of the needle hole of the radio frequency microneedle component is attached to the conductive foil;

[0021] Figure 2 Zero point automatic detection calibration circuit. DETAILED DESCRIPTION

[0022] In order to understand the present application in depth, it will be described in detail. However, the present application has multiple implementation ways and is not limited to the specific examples listed in this paper. The presentation of these examples aims to deepen the overall understanding of the disclosure of the present application.

[0023] Embodiment 1

[0024] A method for out-of-needle zero point self-calibration of a replaceable radio frequency microneedle component, a zero point automatic detection calibration circuit is designed in the hand tool main body for installing the microneedle component; a conductive flat plate is formed on the end face of the radio frequency microneedle component needle hole after the conductive foil is pressed and attached to the end face; the out-of-needle zero point self-calibration method is realized by detecting the displacement of the microneedle needle head in the out-of-needle displacement process, when the needle head touches the conductive flat plate, the radio frequency microneedle changes from open circuit to short circuit, and the value of the displacement sensor at this time is recorded to realize the out-of-needle zero point self-calibration method, as shown in Figure 1 .

[0025] Further, the zero point automatic detection calibration circuit comprises a radio frequency current transformer, a radio frequency current signal conversion circuit, a voltage amplification circuit, a comparator, a 16 bit data latch, a 16 bit zero point data register, and a displacement sensor, as shown in Figure 2

[0026] Further, the radio frequency current transformer is used to collect radio frequency current and realize electrical isolation between the high voltage radio frequency circuit and the low voltage automatic zero point calibration circuit, so as to ensure that the low voltage circuit part can work normally without being damaged; the current transformation ratio of the radio frequency current transformer is between 10:1 and 100:1, and the use frequency range meets 200KHz~10MHz.

[0027] Further, the radio frequency current signal conversion circuit adopts a low offset operational amplifier with a bandwidth higher than 50MHz to convert the 200KHz~10MHz radio frequency alternating current into direct current voltage.

[0028] The radio frequency current signal conversion circuit comprises resistors R1, R2, R3, R4, R6 and R10, capacitors C1, C2 and C3, diodes D1 and D2, and a first operational amplifier; one end of the capacitor C2 and one end of the capacitor C1 are commonly connected to the radio frequency current transformer; the other end of the capacitor C2 is connected to one end of the resistor R1 and one end of the resistor R2, the other end of the capacitor C1 is connected to the other end of the resistor R1, one end of the resistor R10, one end of the capacitor C3, and port 3 of the first operational amplifier; the other end of the capacitor C3 and the other end of the resistor R10 are grounded (GND); the other end of the resistor R2 is connected to one end of the resistor R3, port 2 of the first operational amplifier, and one end of the resistor R6; the other end of the resistor R3 is connected to one end of the resistor R4 and the positive electrode of the diode D1; the other end of the resistor R6 is connected to the negative electrode of the diode D2, the negative electrode of the diode D1 is connected to port 1 of the first operational amplifier and the positive electrode of the diode D2.

[0029] Further, the voltage amplification circuit adopts a high voltage slew rate operational amplifier to amplify the voltage of about 100mV to 2V. The output power of the zero point self-calibration radio frequency is very low, in order to ensure that the micro-needle tip is not burned out by the conductive foil short circuit, the voltage of the front stage output of the micro-needle circuit changes at about 100mV.

[0030] ​The voltage amplification circuit comprises a resistor R5, a capacitor C5 and a second operational amplifier; one end of the resistor R5, one end of the capacitor C5 and port 6 of the second operational amplifier are connected with the other end of the resistor 4 (the radio frequency current signal conversion circuit); port 5 of the second operational amplifier is connected with the other end of the resistor R6 and the negative electrode of the diode D2; port 7 of the second operational amplifier is connected with the other end of the resistor R5, the other end of the capacitor C5 and one end of the resistor 8; the positive power port of the second operational amplifier is connected with VCC, and the negative power port is grounded (GND).

[0031] Further, the comparator adopts a high-speed comparator, and the zero-point calibration threshold voltage is 1.25V. When the output signal of the comparator generates a falling edge, the data of the stored displacement sensor is triggered.

[0032] The comparator comprises a resistor R8 and a third operational amplifier, the other end of the resistor R8 is connected with port 3 of the third operational amplifier, port 2 of the third operational amplifier is connected with 1.25V voltage, and port 1 of the third operational amplifier is connected with the radio frequency device, the 16bit data latch and the 16bit zero-point data register respectively.

[0033] Further, the 16bit data latch is used for storing the displacement value of the stored sensor; the 16bit zero-point data register is used for storing the displacement value of the displacement sensor at the working displacement zero point after calibration, and the data of the data register is not lost after power failure. The 16bit data latch and the 16bit zero-point data register are connected with the displacement sensor.

[0034] Further, the displacement sensor adopts an absolute linear displacement sensor, which is connected with the displacement advancing mechanism of the microneedle in structure; the range of the displacement sensor is 15mm, which is greater than the maximum displacement stroke 10mm of the microneedle, the sensing precision is higher than the use precision 0.1mm of the device, and 0.05mm is adopted; the linear displacement position feedback of the microneedle is used.

[0035] Further, the material of the conductive foil used for forming the conductive flat plate is aluminum foil; and the thickness of the conductive flat plate is between 0.05mm and 0.2mm.

[0036] Further, the radio frequency range of the radio frequency microneedle component is 200KHz-10MHz.

[0037] Embodiment 2

[0038] A method for self-calibration of the microneedle zero point of the replaceable radio frequency microneedle component, and the self-calibration process steps are as follows:

[0039] Step 1, the radio frequency device replaces a new radio frequency microneedle component;

[0040] Step 2, the device recognizes the new RF microneedle component initiates energy output and needle step out;

[0041] Step 3, RF micro energy continues to output;

[0042] Step 4, the RF microneedle is pushed out at a step rate of 0.05 mm / ms;

[0043] Step 5, when the microneedle touches the conductive plate, the latch displacement sensor value is triggered into the data latch;

[0044] Step 6, the stored displacement data value is stored into the zero point data register;

[0045] Step 7, the RF device is notified that the needle zero point calibration is complete.

[0046] The content not described in detail in the specification of the present application is the prior art known to those skilled in the art. Although the above describes the specific embodiments of the present application for the purpose of facilitating the understanding of the present application by those skilled in the art, it should be clear that the present application is not limited to the scope of the specific embodiments, and for those skilled in the art, it is obvious that various changes are within the spirit and scope of the present application defined and determined by the appended claims, and all the inventions utilizing the concept of the present application are within the scope of protection.

Claims

1. A method of needle-out zero self-calibration of a replaceable radio frequency microneedle component, characterized by, The zero point automatic detection calibration circuit is designed inside the hand tool body of the microneedle component; a conductive foil is pressed against the end face of the needle hole of the radio frequency microneedle component to form a conductive flat plate on the end face; the zero point self-calibration method of the needle is realized by detecting the displacement sensor value when the radio frequency microneedle is triggered to change from open circuit to short circuit when touching the conductive flat plate during the needle displacement process.

2. The method of claim 1, wherein, The zero point automatic detection calibration circuit comprises a radio frequency current transformer, a radio frequency current signal conversion circuit, a voltage amplification circuit, a comparator, a 16bit data latch, a 16bit zero point data register and a displacement sensor.

3. The method of claim 2, wherein, The radio frequency current transformer is used for collecting radio frequency current and realizing electrical isolation between the high-voltage radio frequency circuit and the low-voltage automatic zero point calibration circuit, so as to ensure that the low-voltage circuit part can work normally without being damaged; the current variable ratio of the radio frequency current transformer is between 10:1 and 100:1, and the use frequency range meets 200KHz~10MHz.

4. The method of claim 1, wherein, The radio frequency current signal conversion circuit adopts a low-offset operational amplifier with a bandwidth higher than 50MHz to convert the 200KHz~10MHz radio frequency alternating current into direct current voltage.

5. The method of claim 1, wherein, The voltage amplification circuit adopts a high-voltage slew rate operational amplifier to amplify the voltage of about 100mV to 2V.

6. The method of claim 1, wherein, The comparator adopts a high-speed comparator, and the zero point calibration threshold voltage is 1.25V. When the output signal of the comparator produces a falling edge, the stored displacement sensor data is triggered.

7. The method of claim 1, wherein, The 16bit data latch is used for the displacement value of the stored sensor; the 16bit zero point data register is used for storing the displacement sensor value at the working displacement zero point after calibration, and the data in the data register is not lost after power failure.

8. The method of claim 1, wherein, The displacement sensor adopts an absolute linear displacement sensor which is connected to the displacement advancing mechanism of the microneedle in structure; the range of the displacement sensor is 15mm which is greater than the maximum displacement stroke of 10mm of the microneedle, the sensing accuracy is higher than the needle ejection accuracy of 0.1mm of the device, and 0.05mm is adopted; the linear displacement position feedback of the microneedle is used.

9. The method of claim 1, wherein, The material of the conductive foil used for forming the conductive flat plate is aluminum foil; the thickness of the conductive flat plate is between 0.05mm and 0.2mm.

10. The method of claim 1, wherein, The radio frequency frequency range of the radio frequency microneedle component is 200KHz~10MHz.

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