Vaginoscope diagnostic system based on air bag self-adaptive expansion and double-light-path cooperative positioning

Abstract

The invention relates to the technical field of medical instruments. In order to solve the problem of dilatation discomfort in the prior art, the invention provides a colposcope diagnostic system based on air bag self-adaptive dilatation and dual-optical-path cooperative positioning. The system comprises a host, an air bag assembly, a dual-optical-path imaging assembly and a control module. The control module is connected with the air bag assembly, the double-light-path imaging assembly and the main machine and used for coordinating work of all the assemblies. The air bag assembly is used for realizing self-adaptive expansion of the vagina; the double-light-path imaging assembly is used for acquiring images in the vagina; and the host is used for processing, analyzing and displaying the image. According to the colposcope diagnostic system based on air bag self-adaptive expansion and double-light-path cooperative positioning, self-adaptive expansion of the vagina is achieved through the air bag assembly, and the comfort level and adaptability of a patient are improved; the dual-optical-path imaging assembly can synchronously obtain multi-dimensional images, and the lesion positioning and imaging definition is improved; the control module coordinates all the components to work efficiently, the host machine achieves comprehensive image processing, and the diagnosis accuracy and efficiency are remarkably improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a colposcope diagnosis system based on airbag self-adaptive expansion and double optical path cooperative positioning. BACKGROUND

[0002] The colposcope diagnosis system is a gynecological medical device that magnifies the epithelial tissue of the cervix, vagina and vulva through an optical magnification device, and combines with light source illumination to enable the doctor to clearly observe the tiny lesions that cannot be identified by the naked eye. It can locate and guide biopsy at suspicious sites, assist in the diagnosis of cervical lesions, vaginal inflammation and other diseases, and is an important tool for gynecological disease screening and diagnosis.

[0003] The existing colposcope diagnosis system has obvious limitations in clinical application: the expansion method is mainly mechanical rigid expansion, which causes discomfort and easily leads to patient discomfort and even tissue damage. SUMMARY

[0004] The present application provides a colposcope diagnosis system based on airbag self-adaptive expansion and double optical path cooperative positioning to solve the problem of discomfort in the prior art.

[0005] The technical scheme adopted by the present application is as follows: A colposcope diagnosis system based on airbag self-adaptive expansion and double optical path cooperative positioning, comprising a host computer, an airbag assembly, a double optical path imaging assembly and a control module; the control module is connected to the airbag assembly, the double optical path imaging assembly and the host computer respectively, and is used to coordinate the work of each component; the airbag assembly is used to realize self-adaptive expansion of the vagina; the double optical path imaging assembly is used to obtain images inside the vagina; and the host computer is used to process, analyze and display the images.

[0006] Further, the airbag assembly comprises an airbag body, an inflation device and a pressure sensor; the inflation device is connected to the airbag body through an inflation pipe and is used to inflate the airbag body; the airbag body is made of medical flexible material, has a ring structure and is sleeved outside the double optical path imaging assembly, and its inner wall comprises an inner ring wall that is attached to the outer peripheral surface of the double optical path imaging assembly and an outer ring wall that faces away from the double optical path imaging assembly; the pressure sensor is arranged on the inner ring wall of the airbag body and is uniformly distributed along the circumference of the ring structure, and is used to detect the pressure inside the airbag body and transmit the pressure signal to the control module.

[0007] Further, the double optical path imaging assembly comprises a first optical path module and a second optical path module; the first optical path module is used to obtain high-definition white light images inside the vagina; and the second optical path module is used to obtain fluorescence images inside the vagina.

[0008] Further, the first light path module comprises a first light source, a first objective lens and a first image sensor; the first light source is a white light source, and the first image sensor is configured to receive reflected light focused by the first objective lens and form a white light image.

[0009] The first light source is a white light source, a three-primary-color LED combined light source is adopted, the color temperature can be adjusted in a range of 4000K-6000K, and the illumination uniformity of the light source irradiated on the imaging area is greater than or equal to 90%; The numerical aperture of the first objective lens is 0.3-0.35, the working distance is adapted to the range of 8-25mm of the vaginal expansion, and the distortion rate is less than or equal to 2%; The first image sensor is a high-definition CMOS image sensor, the effective pixel is greater than or equal to 5 million, the pixel size is greater than or equal to 2μm, and the signal-to-noise ratio is greater than or equal to 42dB; and the first image sensor is linked with the airbag pressure sensor, when the pressure change is greater than or equal to 0.5kPa, the acquisition frame rate is automatically increased from 15fps to 30fps, and the original frame rate is restored after the pressure is stable.

[0010] Further, the second light path module comprises a second light source, a second objective lens and a second image sensor; the second light source is a fluorescence light source, configured to excite the diseased tissue to emit fluorescence; and the second image sensor is configured to receive fluorescence signals focused by the second objective lens and form a fluorescence image.

[0011] Further, the host is configured to realize image fusion, magnification and measurement functions.

[0012] Further, the inflation device is a miniature electric inflation pump, the pressure sensor is a high-precision thin film pressure sensor, the first light source is an LED white light source, the first image sensor is a high-definition CMOS image sensor, the second light source is a 405nm laser fluorescence light source, the second image sensor is a high-sensitivity CCD image sensor, and the control module adopts an STM32 series microcontroller.

[0013] Further, the host realizes the image fusion, magnification and measurement functions in the following specific manners: In terms of image fusion, after receiving the white light image and the fluorescence image transmitted by the control module, the host performs registration through preset calibration parameters, corrects image deviation caused by physical position difference of the two light paths, and then uses pixel-level fusion technology to superimpose anatomical structure details of the white light image and lesion identification information of the fluorescence image, to generate a fusion image with anatomical positioning and lesion display, thereby facilitating doctors to intuitively identify lesion positions.

[0014] The image zoom-in function is realized by the digital zoom technology of the host computer, pixel interpolation processing is performed on the received fusion image with anatomical positioning and lesion display, a local area can be zoomed in by 1-10 times, and meanwhile, the definition of the zoomed-in image is optimized through the image enhancement algorithm, details are avoided, and the needs of doctors for observing micro lesions are met.

[0015] The measurement function is that the host computer identifies feature points in the image based on the fused image through the SIFT algorithm, the doctor selects a measurement area through an operation interface, proportional conversion is performed according to the image resolution and the optical magnification, the length and area of the lesion are calculated, and the measurement result is marked on the image.

[0016] The beneficial effects of the present application are: The colposcope diagnosis system based on the adaptive expansion of the air bag and the cooperative positioning of the double optical paths disclosed in the present application realizes the adaptive expansion of the vagina through the air bag assembly, improves the comfort and adaptability of the patient, the double optical path imaging assembly can synchronously acquire multi-dimensional images, improves the lesion positioning and imaging definition, the control module coordinates the efficient work of each component, the host computer realizes image comprehensive processing, and the diagnosis accuracy and efficiency are significantly improved. BRIEF DESCRIPTION OF DRAWINGS

[0017] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the drawings needed to be used in the embodiments or the prior art description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.

[0018] Figure 1 It is a block diagram of the colposcope diagnosis system based on the adaptive expansion of the air bag and the cooperative positioning of the double optical paths. Figure 2 It is a structural diagram of the air bag assembly. Figure 3 It is a block diagram of the double optical path imaging assembly. DETAILED DESCRIPTION

[0019] In the description of the present application, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and therefore cannot be understood as indicating or implying that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application.

[0020] The following disclosure provides many different embodiments or examples for implementing different structures of the present invention. To simplify the disclosure of the present invention, the components and arrangements of specific examples are described below. Of course, these are merely examples and are not intended to limit the present invention.

[0021] The embodiments of the invention will now be described in detail with reference to the accompanying drawings.

[0022] like Figure 1 As shown, the colposcopy diagnostic system based on balloon adaptive expansion and dual-optical-path cooperative positioning disclosed in this embodiment includes a host 1, a balloon assembly 2, a dual-optical-path imaging assembly 3, and a control module 4.

[0023] The control module 4 is connected to the airbag assembly 2, the dual-beam imaging assembly 3 and the host 1 respectively, and is used to coordinate the work of each assembly; the airbag assembly 2 is used to realize the adaptive expansion of the vagina; the dual-beam imaging assembly 3 is used to acquire images inside the vagina; and the host 1 is used to process, analyze and display the images.

[0024] The beneficial effects of the above technical solution are as follows: the airbag assembly 2 enables vaginal adaptive expansion, improving patient comfort and fit; the dual-optical-path imaging assembly 3 can simultaneously acquire multi-dimensional images, improving lesion localization and imaging clarity; the control module 4 coordinates the efficient operation of each component, and the host computer performs comprehensive image processing, significantly improving diagnostic accuracy and efficiency.

[0025] Furthermore, such as Figure 2 As shown, the airbag assembly 2 includes an airbag body 21, an inflation device 22, and a pressure sensor 23; the inflation device 22 is connected to the airbag body 21 through an inflation tube and is used to inflate the airbag body 21. like Figure 1 As shown, the airbag body 21 is made of medical flexible material, has a ring structure and is sleeved on the outside of the dual-light path imaging component 3. Its inner wall includes an inner ring wall that fits against the outer peripheral surface of the dual-light path imaging component 3 and an outer ring wall that is away from the dual-light path imaging component 3. The pressure sensor 23 is set on the inner ring wall of the airbag body 21 and is evenly distributed along the circumference of the ring structure. It is used to detect the pressure inside the airbag body 21 and transmit the pressure signal to the control module.

[0026] Furthermore, such as Figure 3 As shown, the dual-optical-path imaging component 3 includes a first optical path module 31 and a second optical path module 32; the first optical path module 31 is used to acquire high-definition white light images inside the vagina; the second optical path module 32 is used to acquire fluorescence images inside the vagina.

[0027] The above scheme has remarkable beneficial effects: first, the high-definition white light image can clearly present the anatomical structure and morphological details of the intra-vaginal tissue, providing an intuitive physiological structure reference for the doctor; second, the fluorescent image can specifically display the lesion tissue such as abnormal hyperplastic cells, and accurately mark the lesion area through the fluorescent signal, making up for the deficiency of white light imaging in identifying early or occult lesions; third, the two image information is complementary, and after combination, the dual diagnostic basis of "structure positioning + functional marking" can be realized, which greatly improves the lesion detection rate and positioning accuracy, reduces the risk of missed diagnosis and misdiagnosis, and provides more reliable guidance for subsequent biopsy and treatment.

[0028] Further, the first light path module 31 comprises a first light source 311, a first objective lens 312 and a first image sensor 313; the first light source 311 is a white light source, and the first image sensor 313 is used to receive reflected light focused by the first objective lens 312 and form a white light image.

[0029] The first light source 311 is a white light source, which adopts a three-primary-color LED combined light source, and the color temperature can be adjusted in the range of 4000K-6000K, and the illumination uniformity of the light source irradiated on the imaging area is ≥90%; The numerical aperture of the first objective lens 312 is 0.3-0.35, and the working distance is adapted to the vaginal dilation range of 8-25mm, and the distortion rate is ≤2%; The first image sensor 313 is a high-definition CMOS image sensor, with effective pixels ≥5 million and pixel size ≥2μm, and signal-to-noise ratio ≥42dB; and the first image sensor 313 is linked with the airbag pressure sensor 23, and when the pressure change is ≥0.5kPa, the acquisition frame rate is automatically increased from 15fps to 30fps, and the original frame rate is restored after the pressure is stable, ensuring clear capture of the fine structure of the vagina during dynamic dilation.

[0030] The above technical scheme has the beneficial effects that: through the combination of the three-primary-color LED with adjustable color temperature and the high-pixel CMOS, the detail restoration degree of different vaginal tissues is improved.

[0031] Further, the second light path module 32 comprises a second light source 321, a second objective lens 322 and a second image sensor 323; the second light source 321 is a fluorescent light source, which is used to excite the lesion tissue to emit fluorescence; and the second image sensor 323 is used to receive the fluorescent signal focused by the second objective lens 322 and form a fluorescent image.

[0032] Further, the control module 4 can control the inflation amount of the inflation device 22 according to the pressure signal detected by the pressure sensor 23, so that the dilation degree of the airbag body 21 adapts to the physiological structure of the patient's vagina; at the same time, the control module 4 can also control the working state of the first light path module 31 and the second light path module 32, and transmit the obtained white light image and fluorescent image to the host computer 1.

[0033] Further, the host 1 is used to realize the fusion, magnification, and measurement functions of images.

[0034] Further, the inflation device 22 is a miniature electric inflation pump, and the pressure sensor 23 is a high-precision thin-film pressure sensor; the first light source 311 is an LED white light source, and the first image sensor 313 is a high-definition CMOS image sensor; the second light source 321 is a 405 nm laser fluorescence light source, and the second image sensor 323 is a high-sensitivity CCD image sensor; and the control module 4 adopts an STM32 series microcontroller.

[0035] Further, the specific manner in which the host 1 realizes the fusion, magnification, and measurement functions of images is as follows: In terms of image fusion, after the host 1 receives the white light image and the fluorescence image transmitted by the control module 4, the host 1 performs registration through preset calibration parameters (determined based on the fixed installation pose of the dual-light-path imaging assembly 3), corrects the image offset caused by the physical position difference between the two light paths, and then uses pixel-level fusion technology to superimpose the anatomical structure details of the white light image and the lesion identification information of the fluorescence image, thereby generating a fusion image that combines anatomical positioning and lesion display, which facilitates the intuitive identification of the lesion position by the doctor.

[0036] The image magnification function is realized through the digital zoom technology of the host 1, which performs pixel interpolation processing on the received fusion image that combines anatomical positioning and lesion display, and can magnify the local area by 1-10 times, while optimizing the definition of the magnified image through image enhancement algorithms to avoid detail blur, thereby meeting the needs of the doctor for observing small lesions. The pixel interpolation processing is a digital image processing technology used to supplement new pixels when the image is enlarged, so as to improve the definition and integrity of the enlarged image. When the host 1 enlarges the image, the number of pixels in the original image is fixed, and direct enlargement will cause the picture to be blurred and jagged. Through pixel interpolation processing, the system will calculate and generate new pixels based on the color, brightness, and other information of the adjacent pixels in the original image, and fill them in the gaps, so that the enlarged image is smooth and the details are clearer, thereby allowing the doctor to clearly observe the details of the enlarged lesion.

[0037] The measurement function is that the host 1 identifies the feature points (such as the edges of the lesion) in the fused image based on the SIFT (Scale-Invariant Feature Transform) algorithm, and after the doctor selects the measurement area through the operation interface, the length and area of the lesion are calculated according to the image resolution and optical magnification, and the measurement results are marked on the image, with a measurement accuracy of 0.01 mm.

[0038] In the diagnosis using the colposcope diagnostic system based on the adaptive expansion of the air bag and the cooperative positioning of the double optical path, the double optical path imaging assembly 3 with the air bag body 21 is slowly put into the patient's vagina. Then, the control module 4 starts the inflation device 22 to inflate the air bag body 21. The pressure sensor 23 detects the pressure inside the air bag body 21 in real time and transmits the pressure signal to the control module 4. When the pressure reaches the preset initial threshold value, the control module 4 controls the inflation device 22 to stop inflating, at which time the air bag body 21 is preliminarily expanded, and the position of the double optical path imaging assembly 3 is fixed.

[0039] Then, the control module 4 controls the first light path module 31 and the second light path module 32 to work. The first light source 311 emits white light, which is focused by the first objective lens 312 and irradiated on the vaginal tissue. The reflected light is imaged on the first image sensor 313 by the first objective lens 312, forming a white light image and transmitting it to the host computer 1. At the same time, the second light source 321 emits fluorescence, which excites the lesion tissue to emit fluorescence. The fluorescence signal is focused by the second objective lens 322 and received by the second image sensor 323, forming a fluorescence image and transmitting it to the host computer 1.

[0040] The host computer 1 performs fusion processing on the white light image and the fluorescence image. The doctor can clearly identify the location, size and shape of the lesion site by observing the fused image. During the examination, if it is necessary to adjust the expansion degree of the air bag body 21, the doctor can send instructions to the control module 4 through the host computer 1. The control module 4 controls the inflation or deflation of the inflation device 22 according to the instructions, so that the pressure of the air bag body 21 is kept within a suitable range.

[0041] After the examination, the control module 4 controls the inflation device 22 to deflate, and the double optical path imaging assembly 3 is taken out of the patient's vagina, completing the diagnosis process.

Claims

1. A colposcope diagnostic system based on adaptive expansion of air bag and dual optical path cooperative positioning, characterized in that, The device comprises a host, an airbag assembly, a double optical path imaging assembly and a control module; the control module is connected with the airbag assembly, the double optical path imaging assembly and the host respectively, and is used for coordinating the work of each component; the airbag assembly is used for realizing self-adaptive expansion of the vagina; the double optical path imaging assembly is used for acquiring images in the vagina; and the host is used for processing, analyzing and displaying the images.

2. The colposcope diagnostic system based on adaptive expansion of the air bag and cooperative positioning of double light paths according to claim 1, characterized in that, The airbag assembly comprises an airbag body, an inflating device and a pressure sensor; the inflating device is connected with the airbag body through an inflating pipe and is used for inflating the airbag body; the airbag body is made of medical flexible material, has a ring structure and is sleeved outside the double optical path imaging assembly, and the inner wall thereof comprises an inner ring wall which is attached to the outer peripheral surface of the double optical path imaging assembly and an outer ring wall which is away from the double optical path imaging assembly; the pressure sensor is arranged on the inner ring wall of the airbag body and is uniformly distributed along the circumferential direction of the ring structure, and is used for detecting the pressure inside the airbag body and transmitting the pressure signal to the control module.

3. The colposcope diagnostic system based on adaptive expansion of the air bag and cooperative positioning of double light paths according to claim 2, characterized in that, The double optical path imaging assembly comprises a first optical path module and a second optical path module; the first optical path module is used for acquiring high-definition white light images in the vagina; and the second optical path module is used for acquiring fluorescence images in the vagina.

4. The colposcope diagnostic system based on adaptive expansion of the air bag and cooperative positioning of double light paths according to claim 3, characterized in that, The first optical path module comprises a first light source, a first objective lens and a first image sensor; the first light source is a white light source, and the first image sensor is used for receiving reflected light focused by the first objective lens and forming white light images; The first light source is a white light source, adopts a three-primary-color LED combined light source, the color temperature can be adjusted in the range of 4000K-6000K, and the illumination uniformity of the light source irradiated on the imaging area is greater than or equal to 90%; The numerical aperture of the first objective lens is 0.3-0.35, the working distance is adapted to the vagina expansion range of 8-25mm, and the distortion rate is less than or equal to 2%; The first image sensor is a high-definition CMOS image sensor, the effective pixel is greater than or equal to 5 million, the pixel size is greater than or equal to 2μm, and the signal-to-noise ratio is greater than or equal to 42dB; and the first image sensor is linked with the airbag pressure sensor, when the pressure change is greater than or equal to 0.5kPa, the acquisition frame rate is automatically increased from 15fps to 30fps, and the original frame rate is restored after the pressure is stable.

5. The colposcope diagnostic system based on adaptive expansion of the air bag and cooperative positioning of the double light path according to claim 4, characterized in that, The second optical path module comprises a second light source, a second objective lens and a second image sensor; the second light source is a fluorescence light source and is used for exciting the diseased tissue to emit fluorescence; and the second image sensor is used for receiving fluorescence signals focused by the second objective lens and forming fluorescence images.

6. The colposcope diagnostic system based on adaptive expansion of the air bag and cooperative positioning of double light paths according to any one of claims 1-5, characterized in that, The host is used for realizing the fusion, amplification and measurement functions of the images.

7. The colposcope diagnostic system based on adaptive expansion of the air bag and cooperative positioning of double light paths according to claim 4, characterized in that, The inflating device is a miniature electric inflating pump, the pressure sensor is a high-precision thin film pressure sensor, the first light source is an LED white light source, the first image sensor is a high-definition CMOS image sensor, the second light source is a 405nm laser fluorescence light source, the second image sensor is a high-sensitivity CCD image sensor, and the control module adopts an STM32 series microcontroller.

8. The colposcope diagnostic system based on adaptive expansion of the air bag and cooperative positioning of double light paths according to claim 6, characterized in that, The specific mode in which the host realizes the fusion, amplification and measurement functions of the images is as follows: In terms of image fusion, after the host receives the white light image and the fluorescent image transmitted by the control module, it performs registration through preset calibration parameters, corrects the image offset caused by the physical position difference of the two light paths, and then uses pixel-level fusion technology to superimpose the anatomical structure details of the white light image and the lesion identification information of the fluorescent image, generating a fusion image with both anatomical positioning and lesion display, which facilitates the doctor's intuitive identification of the lesion location. The image magnification function is realized through the digital zoom technology of the host. It performs pixel interpolation processing on the received fusion image with both anatomical positioning and lesion display, which can magnify the local area by 1-10 times. At the same time, through image enhancement algorithm, the clarity of the enlarged image is optimized to avoid detail blur, meeting the doctor's observation needs of small lesions. The measurement function is based on the fused image. The host identifies the feature points in the image through the SIFT algorithm. After the doctor selects the measurement area through the operation interface, the length and area of the lesion are calculated by proportion conversion according to the image resolution and optical magnification, and the measurement results are marked on the image.

Images