Tissue positioning disc

Abstract

The application discloses a kind of tissue positioning disc, belong to medical instrument field, comprising: base;Press frame, with base detachable connection, press frame is provided with elastic film, press frame rotates to a closed position along a closed direction, and elastic film is abutted to closed surface, and the movement of tissue sample in closed direction in accommodating cavity is limited;Mobile support, with press frame sliding connection, mobile support is not less than two, and the sliding track of mobile support does not coincide, mobile support is through setting with stroke sliding slot one, and the stroke sliding slot one of adjacent mobile support constitutes center positioning channel;Moving block, with mobile support sliding connection, moving block is through setting with edge positioning channel;When press frame moves to closed position, the extension direction of center positioning channel and edge positioning channel is coincident with closed direction, so that center positioning channel and edge positioning channel form projection on elastic film along closed direction.

Description

Technical Field

[0001] This invention belongs to the field of medical device technology, specifically relating to a tissue positioning disc. Background Technology

[0002] In tumor pathology research, obtaining representative samples of adjacent normal tissue is crucial for clarifying tumor boundaries, assessing the degree of invasion, and developing subsequent treatment plans. However, due to the varying shapes and irregular boundaries of surgically removed tumor tissue blocks, accurately and efficiently obtaining adjacent normal samples remains a significant challenge. Currently, clinical practice largely relies on experienced physicians using sampling strategies such as the "five-point method," dividing the resection block spatially and determining sampling sites based on personal experience. While this method can achieve good results in experienced operators, its operational procedures heavily depend on the surgeon's subjective judgment and proficiency. Inexperienced physicians, however, often need to repeatedly select and mark sampling points, resulting in a lengthy operation and low sampling rates. Low sampling efficiency leads to delays in sample preparation and analysis, which in turn affects timely diagnosis and treatment decisions for patients.

[0003] Therefore, a sampling auxiliary device is designed to locate near-tumor tissue samples and mark the sampling point. This auxiliary device is specifically a tissue positioning disc. Summary of the Invention

[0004] To overcome the problems mentioned in the background art, a device is proposed that can conveniently mark any point on a tissue sample based on the fixed morphology of an irregularly shaped adjacent cancer tissue sample, so that researchers can quickly select and determine the sampling point. The specific technical solution adopted by this invention is as follows:

[0005] A tissue positioning disk includes: a base having a closed surface with a receiving cavity; a pressure frame detachably connected to the base, the pressure frame having an elastic membrane, wherein when the pressure frame rotates to a closed position along a closing direction, the elastic membrane abuts against the closed surface and restricts the movement of the tissue sample in the receiving cavity in the closing direction; a movable support slidably connected to the pressure frame, wherein there are at least two movable supports and the sliding trajectories of the movable supports do not overlap, each movable support having a travel groove, and adjacent movable supports having a central positioning channel along the closing direction when the pressure frame moves to the closed position; and a movable block slidably connected to the movable supports, the movable block having an edge positioning channel.

[0006] When the pressure frame moves to the closed position, the extension directions of the center positioning channel and the edge positioning channel coincide with the closing direction, so that the center positioning channel and the edge positioning channel form a projection on the elastic membrane along the closing direction.

[0007] Furthermore, the outer wall of the pressure frame is provided with several travel grooves, the number of which is at least two. The movable bracket is slidably connected to the travel grooves and slides along the extension direction of the travel grooves.

[0008] Furthermore, the movement trajectory of the movable support along the second stroke groove is a straight line segment, and adjacent second stroke grooves are not parallel to each other; each movable support is slidably connected with at least two movable blocks, so that the edge positioning channel of each movable block can project onto multiple positions of the elastic membrane along the closing direction when sliding along the moving movable support.

[0009] Furthermore, the movable support includes a crossbeam and legs that are fixedly connected, a first travel groove is provided on the crossbeam, and the end of the leg facing away from the crossbeam is slidably connected to the second travel groove.

[0010] Furthermore, the movable support also includes an elastic element one, and the outer wall of the pressure frame is provided with a limiting groove. During the process of the movable support being inserted into the travel groove two along the closing direction, the elastic element one is squeezed and deformed against the outer wall of the pressure frame. After the movable support moves to a mating position, the elastic element one is inserted into the limiting groove towards the end of the pressure frame and elastically resets, thereby restricting the movement of the movable support along the closing direction or the opposite direction of the closing direction. The limiting groove and the travel groove two correspond one-to-one and are parallel to each other. The pressure frame has a top surface and a side surface, wherein the travel groove two is provided on the top surface of the pressure frame, and the limiting groove is provided on the side surface of the pressure frame. During the process of the movable support moving from a distance to the mating position along the closing direction, the elastic element one sequentially contacts and squeezes the top surface and the side surface and finally slides into the limiting groove. The elastic element is connected to the support leg. The end of the elastic element away from the support leg is provided with a protrusion. When the movable bracket moves to the mating position, the protrusion enters the limiting slide groove and abuts against the inner wall of the limiting slide groove closest to the top surface. This allows the movable bracket to maintain its position in the closing direction when it tends to move in the reverse closing direction under the drive of external force, so as to prevent the movable bracket from falling off the pressure frame and not affect its movement along the travel slide groove and the limiting slide groove.

[0011] Furthermore, the first elastic element is an elastic plate. When the first elastic element is not subjected to external force, its end away from the support leg does not contact the support leg. When the first elastic element contacts the pressure frame and they are pressed against each other, the first elastic element deforms and its end in contact with the pressure frame moves away from the support leg, so that when the first elastic element moves to the mating position, it moves toward the support leg and abuts against the outer wall of the pressure frame.

[0012] Furthermore, the movable block includes a block body with an edge positioning channel extending through it and two elastic elements. The elastic elements are fixedly connected to the block body. When the movable block is slidably connected to the movable support, the end of the elastic element away from the block body abuts against the end of the movable support away from the block body, thereby restricting the movement of the movable block in the closing direction or the opposite direction of the closing direction. A protrusion is provided at the end of the elastic element away from the block body, and the protrusion is configured to protrude towards the other side of the elastic element. When the pressure frame is in the closed position, the elastic element undergoes elastic deformation and elastic reset sequentially as the movable block approaches and connects to the movable support in the closing direction: when the protrusions on both sides contact and press against the movable support, they drive the elastic element to undergo elastic deformation, causing the end of the elastic element away from the block body to bend in the direction away from the movable support; when the block continues to move and abuts against the movable support, the protrusion passes over the movable support in the closing direction and abuts against the end of the crossbeam away from the block body, causing the elastic element to reset under its own elastic action and restricting the movement of the movable block in the closing direction.

[0013] Furthermore, the cavity wall of the receiving cavity is provided with several threaded holes, which open onto the outer wall of the base. Each threaded hole is connected to a positioning bolt. When the positioning bolt rotates around its own axis, the length of the portion of the positioning bolt extending into the receiving cavity changes. The central axes of adjacent positioning bolts are not parallel. After the pressure frame moves to the closed position, the movement of the tissue sample in the closed direction is restricted by the elastic membrane and the receiving cavity. By turning the positioning bolts, the position of their ends within the receiving cavity is changed, allowing the tissue sample to be squeezed from different directions, thereby completely restricting the movement of the tissue sample.

[0014] Furthermore, the pressure frame is provided with an operating area, which is aligned with the receiving cavity along the closing direction.

[0015] Furthermore, the elastic membrane is an elastic film with a thickness of less than 0.5 mm, and the elastic membrane is made of a transparent material.

[0016] Alternatively, unlike the above scheme, the movement trajectory of the movable support along the second travel groove is circular, allowing the movable support to slide along the second travel groove while rotating around an axis. The axis around which the movable support rotates extends in the closed direction and coincides with the center of the second travel groove. Each movable support is slidably connected to at least two movable blocks, allowing the edge positioning channel of each movable block to project onto multiple positions of the elastic membrane along the closed direction when sliding along the moving movable support. The second travel grooves are all located at the ends of the pressure frame away from the base. Adjacent second travel grooves are not connected to each other, have different circumferences, and coincide in center. Adjacent movable supports do not contact each other when moving along their corresponding second travel grooves.

[0017] The beneficial effects of this invention are:

[0018] 1. The present invention is provided with a pressure frame and a base that can be closed, wherein the base is provided with a receiving cavity and a positioning bolt that can be spirally inserted into the receiving cavity, and an elastic membrane is provided at the end of the pressure frame facing the base. After the pressure frame is closed, the elastic membrane and the positioning bolt can effectively lock the movement state of tissue samples of various shapes in the receiving cavity.

[0019] 2. The present invention is provided with a movable support that is slidably connected to the pressure frame, and a movable block that is slidably connected to the movable support. The movable block and the overlapping movable support have an edge positioning channel and a center positioning channel respectively along the closing direction. The edge positioning channel and the center positioning channel can be projected at any position on the elastic membrane as the movable support and the movable block move, thereby enabling convenient marking of the sampling point.

[0020] 3. The present invention is provided with elastic element one and elastic element two. Elastic element one prevents the moving block from detaching from the crossbeam by clamping the moving bracket and locks the relative position of the moving block and the moving bracket when there is no external force driving it. Elastic element two prevents the moving bracket from detaching from the pressure frame by clamping the outer wall of the pressure frame and locks the relative position of the moving bracket and the pressure frame when there is no external force driving it. This allows the user to quickly adjust and fix the sampling point. Attached Figure Description

[0021] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Wherein:

[0022] Figure 1 This is a schematic diagram of the overall structure of the present invention when the pressure frame is in the closed position, as shown in Example 1.

[0023] Figure 2 This is a schematic diagram of the overall structure of the present invention when the pressure frame is disengaged from the closed position in Example 1;

[0024] Figure 3 for Figure 2 A schematic diagram of an overall structure when the intermediate pressure frame does not have an elastic membrane;

[0025] Figure 4 This is a schematic diagram of the structure of the present invention when the pressure frame separates from the base along the closing direction in Example 1;

[0026] Figure 5 for Figure 4 A schematic diagram of a cross-sectional structure;

[0027] Figure 6This is a schematic cross-sectional view of the present invention when the pressure frame moves along the closing direction to the mating position in Example 1;

[0028] Figure 7 A schematic diagram of a movable support structure;

[0029] Figure 8 This is a schematic diagram of the structure of the pressure frame in Embodiment 1 when the movable bracket is in the mating position;

[0030] Figure 9 This is a schematic diagram of an overall structure of the present invention when the positioning bolt is detached from the base in Example 2;

[0031] Figure 10 This is a schematic diagram of the overall structure of the present invention when the pressure frame detaches from the base in Example 2;

[0032] In the diagram, 1. Base; 11. Closed surface; 12. Receiving cavity; 13. Threaded hole; 14. Positioning bolt; 2. Pressure frame; 21. Elastic membrane; 22. Top surface; 221. Stroke groove two; 23. Side; 231. Limiting groove; 24. Operating area; 3. Moving bracket; 31. Crossbeam; 311. Stroke groove one; 312. Center positioning channel; 32. Support leg; 33. Elastic element one; 331. Protrusion one; 4. Moving block; 41. Block body; 411. Edge positioning channel; 42. Elastic element two; 421. Protrusion two. Detailed Implementation

[0033] The technical solutions of the embodiments of the present invention are clearly and completely described below through specific examples. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments. In the absence of conflict, the following embodiments and features in the embodiments can be combined with each other. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0034] Example 1

[0035] Tissue positioning disk, such as Figure 1-8 As shown, it includes: a base 1 with a closed surface 11, the closed surface 11 having a receiving cavity 12, the receiving cavity 12 being used to place the ex vivo tissue sample to be further sampled, the closed surface 11 serving as the top surface 22 of the receiving cavity 12 space when the pressure frame 2 is closed, which is beneficial for users to plan the volume of the three-dimensional tissue sample.

[0036] The pressure frame 2 is detachably connected to the base 1. The pressure frame 2 is equipped with a transparent elastic membrane 21, which is disposable and made of food-grade PE material. When the pressure frame 2 rotates to a closed position along a closing direction, the elastic membrane 21 abuts against the closed surface 11, restricting the movement of the tissue sample within the receiving cavity 12 in the closing direction. By providing the elastic membrane 21, even if the volume of the tissue sample to be sampled exceeds the closed surface 11 by 1-5 mm, the portion exceeding the closed surface 11 is tightened under the action of the elastic membrane 21, which helps to create a stable surface that facilitates puncture by the sampler. Furthermore, the thickness of the elastic membrane 21 is no more than 0.03 mm. The elastic membrane 21 can compress and restrict the movement of the tissue sample based on tension, while the sampling instrument can puncture the elastic membrane 21 without obstruction during the sampling operation after positioning.

[0037] The pressure frame 2 is provided with an operating area 24. Along the closing direction, the operating area 24 is aligned with the receiving cavity 12, which makes it easy for the user to observe the sample in the receiving cavity 12, and thus helps the user to determine the sampling point by combining the five-point sampling method or other sampling point determination methods.

[0038] The movable support 3 is slidably connected to the pressure frame 2. There are at least two movable supports 3, and their sliding trajectories do not overlap. Each movable support 3 is provided with a travel groove 311. When the pressure frame 2 moves to the closed position, the travel groove 311 of adjacent movable supports 3 has a central positioning channel 312 along the closing direction. The central axis of the central positioning channel 312 is perpendicular to the closed surface 11. Therefore, the vertical projection position of the central positioning channel 312 above the ex vivo tissue sample is the position where the sampling instrument first contacts the ex vivo tissue sample when it moves towards the receiving cavity 12 through the central positioning channel 312 and its extension direction.

[0039] The movable block 4 is slidably connected to the movable support 3, and the movable block 4 is provided with an edge positioning channel 411. When the pressure frame 2 moves to the closed position, the extension directions of the central positioning channel 312 and the edge positioning channel 411 are both coincident with the closing direction, so that the central positioning channel 312 and the edge positioning channel 411 form a projection on the elastic membrane 21 and the isolated tissue sample along the closing direction. The projection position formed on the isolated tissue sample is the sampling position after the sampler passes through the edge positioning channel 411. The sampler is specifically a puncture sampling device, whose outer diameter is smaller than the inner diameter of the central positioning channel 312 and the edge positioning channel 411. It can reciprocate along the central axis of the central positioning channel 312 or the edge positioning channel 411, and obtain a smaller volume tissue sample by cutting at the projection position after piercing the isolated tissue sample. In the actual operation of connecting each movable support 3 to two movable blocks 4, inexperienced physicians only need to adjust and control the positional relationship between the movable support 3 and the pressure frame 2, and the positional relationship between the movable block 4 and the movable support 3 under the guidance of the five-point method to successively construct a central positioning channel 312 and four edge positioning channels 411 aligned with the five sampling points. Moreover, the movable block 4 and the movable support 3 are self-locked by elastic element 1 33 and elastic element 2 42 respectively, which can prevent them from being accidentally moved after their positions are determined, significantly simplifying the positioning operation: the tissue sample is positioned by the base 1 connected with the positioning bolt 14. The user only needs to control the sliding of the movable support 3 and the movable block 4 to quickly change the spatial position of the positioning channel, so as to greatly shorten the preparation time before the sampling operation and reduce the operation time, thereby avoiding the delay in sample preparation and analysis, and ultimately achieving timely diagnosis and treatment decisions for the patient's condition.

[0040] A more preferred embodiment is, for example, Figure 1-8 As shown, the outer wall of the pressure frame 2 is provided with several travel grooves 221. The number of travel grooves 221 is at least two. The movable bracket 3 is slidably connected to the travel grooves 221 and slides along the extension direction of the travel grooves 221.

[0041] A more preferred embodiment is, for example, Figure 1-8 As shown, the movement trajectory of the movable support 3 along the travel groove 221 is a straight line segment, and adjacent travel grooves 221 are not parallel to each other. Each movable support 3 is slidably connected to at least two movable blocks 4, so that the edge positioning channel 411 of each movable block 4 can form projections on multiple positions of the elastic membrane 21 along the closing direction when sliding along the movable support 3. Specifically, the projections of the pressure frame 2 and the base 1 in the closing direction are polygons with no less than four sides and at least four travel grooves 221, and the travel grooves 221 exist in pairs symmetrically. Each pair of travel grooves 221 is connected to a movable support 3 to limit the movement stroke of the movable support 3.

[0042] A more preferred embodiment is, for example, Figure 1-8 As shown, the movable support 3 includes a crossbeam 31 and a support leg 32 that are fixedly connected. A first travel groove 311 is provided on the crossbeam 31, and the end of the support leg 32 facing away from the crossbeam 31 is slidably connected to a second travel groove 221.

[0043] A more preferred embodiment is, for example, Figure 1-8 As shown, the movable support 3 also includes an elastic element 33, and the outer wall of the pressure frame 2 is provided with a limiting groove 231. During the process of the movable support 3 inserting into the travel groove 221 in the closing direction, the elastic element 33 is squeezed and deformed against the outer wall of the pressure frame 2. After the movable support 3 moves to a mating position, the elastic element 33 inserts into the limiting groove 231 towards the end of the pressure frame 2 and elastically resets, thereby restricting the movement of the movable support 3 in the closing direction or the opposite direction of the closing direction. The limiting groove 231 corresponds to and is parallel to the travel groove 221. The pressure frame 2 has a top surface 22 and a side surface 23, wherein the travel groove 221 is provided on the top surface 22 of the pressure frame 2, and the limiting groove 231 is provided on the side surface 23 of the pressure frame 2. During the process of the movable support 3 moving from a distance to the mating position in the closing direction, the elastic element 33 sequentially contacts and squeezes the top surface 22 and the side surface 23 and finally slides into the limiting groove 231. The elastic element 33 is connected to the support leg 32. The end of the elastic element 33 facing away from the support leg 32 is provided with a protrusion 331. When the movable bracket 3 moves to the mating position, the protrusion 331 enters the limiting slide groove 231 and abuts against the inner wall of the limiting slide groove 231 closest to the top surface 22. This allows the movable bracket 3 to maintain its position in the closing direction when it tends to move in the opposite direction of closing under the drive of external force, so as to prevent the movable bracket 3 from falling off the pressure frame 2 and not affect its movement along the travel slide groove 221 and the limiting slide groove 231.

[0044] A more preferred embodiment is, for example, Figure 1-8 As shown, the elastic element 33 is an elastic plate. When the elastic element 33 is not subjected to external force, its end away from the support leg 32 does not contact the support leg 32. When the elastic element 33 contacts the pressure frame 2 and they are pressed against each other, the elastic element 33 deforms and its end in contact with the pressure frame 2 moves away from the support leg 32, so that when the elastic element 33 moves to the mating position, it moves toward the support leg 32 and abuts against the outer wall of the pressure frame 2.

[0045] A more preferred embodiment is, for example, Figure 1-8As shown, the movable block 4 includes a block body 41 through which an edge positioning channel 411 is provided and two elastic members 42. The elastic members 42 are fixedly connected to the block body 41. When the movable block 4 is slidably connected to the movable support 3, the end of the elastic member 42 away from the block body 41 abuts against the end of the movable support 3 away from the block body 41, so as to restrict the movable block 4 from moving in the closing direction or the opposite direction of the closing direction. The end of the elastic element 42 facing away from the block 41 is provided with a protrusion 421, and the protrusion 421 is configured to protrude towards the other side of the elastic element 42. When the pressure frame 2 is in the closed position, the elastic element 42 undergoes elastic deformation and elastic reset in sequence as the moving block 4 approaches and connects to the moving bracket 3 in the closing direction: when the protrusions 421 on both sides contact and squeeze the moving bracket 3, the elastic element 42 is driven to undergo elastic deformation, causing the end of the elastic element 42 facing away from the block 41 to bend in the direction away from the moving bracket 3; when the block 41 continues to move and abuts against the moving bracket 3, the protrusion 421 passes over the moving bracket 3 in the closing direction and abuts against the end of the crossbeam 31 facing away from the block 41, so that the elastic element 42 resets under its own elastic action and restricts the movement of the moving block 4 in the closing direction.

[0046] A more preferred embodiment is, for example, Figure 1-8 As shown, the cavity wall of the receiving cavity 12 is provided with several threaded holes 13, which open into the outer wall of the base 1. Each threaded hole 13 is connected to a positioning bolt 14. When the positioning bolt 14 rotates around its own axis, the length of the portion of the positioning bolt 14 extending into the receiving cavity 12 changes. The central axes of adjacent positioning bolts 14 are not parallel. After the pressure frame 2 moves to the closed position, the movement of the tissue sample in the closed direction is restricted by the elastic membrane 21 and the receiving cavity 12. By turning the positioning bolt 14, the position of its end within the receiving cavity 12 is changed, allowing the tissue sample to be squeezed from different directions, thereby completely restricting the movement of the tissue sample.

[0047] Example 2

[0048] Tissue positioning disk, such as Figure 1-8As shown, it includes: a base 1 having a closed surface 11, the closed surface 11 having a receiving cavity 12; a pressure frame 2 detachably connected to the base 1, the pressure frame 2 being provided with an elastic membrane 21, when the pressure frame 2 rotates in a closing direction to a closed position, the elastic membrane 21 abuts against the closed surface 11 and restricts the movement of the tissue sample in the receiving cavity 12 in the closing direction; the pressure frame 2 is provided with an operating area 24 through it, the operating area 24 being aligned with the receiving cavity 12 in the closing direction. The movable support 3 is slidably connected to the pressure frame 2. There are at least two movable supports 3, and the sliding trajectories of the movable supports 3 do not overlap. The movable support 3 is provided with a travel groove 311. When the pressure frame 2 moves to the closed position, the travel groove 311 of the adjacent movable supports 3 has a central positioning channel 312 along the closing direction. Specifically, the elastic membrane 21 is a disposable elastic film with a thickness of less than 0.5 mm. The elastic membrane 21 is made of transparent material, so it will not affect the user's observation of tissue samples. The elastic membrane 21 can compress and restrict the movement of tissue samples based on tension. At the same time, the sampling instrument can puncture the elastic membrane 21 without obstruction during the sampling operation after positioning. The movable block 4 is slidably connected to the movable support 3. The movable block 4 is provided with an edge positioning channel 411. When the pressure frame 2 moves to the closed position, the extension directions of the central positioning channel 312 and the edge positioning channel 411 are both coincident with the closing direction, so that the central positioning channel 312 and the edge positioning channel 411 form a projection on the elastic membrane 21 along the closing direction.

[0049] A more preferred embodiment is, for example, Figure 1-8 As shown, the outer wall of the pressure frame 2 is provided with several travel grooves 221. The number of travel grooves 221 is at least two. The movable bracket 3 is slidably connected to the travel grooves 221 and slides along the extension direction of the travel grooves 221.

[0050] A more preferred embodiment is, for example, Figure 1-10As shown, unlike Embodiment 1, the movement trajectory of the movable support 3 along the second travel groove 221 is circular, allowing the movable support 3 to slide along the second travel groove 221 while rotating around an axis. The axis around which the movable support 3 rotates extends in the closing direction and coincides with the center of the second travel groove 221. Each movable support 3 is slidably connected to at least two movable blocks 4, allowing the edge positioning channel 411 of each movable block 4 to project onto multiple positions of the elastic membrane 21 in the closing direction when sliding along the moving movable support 3. The second travel groove 221 is located at the end of the pressure frame 2 away from the base 1. Adjacent second travel grooves 221 are not connected to each other, and the circumferences of adjacent second travel grooves 221 are different but their centers coincide. Adjacent movable supports 3 do not contact each other when moving along the corresponding second travel groove 221. Specifically, the projections of the pressure frame 2 and the base 1 in the closing direction are circular, and there are at least two second travel grooves 221. Each second travel groove 221 is connected to a movable support 3 to limit the movement stroke of the movable support 3. In addition, in this embodiment, there are at least two limiting slide grooves 231, which are respectively set on the outer wall of the pressure frame 2 facing and away from the central axis of the operation area 24. When the moving bracket 3 slides the second slide groove 221, the elastic element 33 connected to it is respectively engaged in the limiting slide groove, and the elastic element 33 moves synchronously with the moving bracket 3.

Claims

1. An organization positioning disk, characterized in that, include, The base has a closed surface, and the closed surface has a receiving cavity; The pressure frame is detachably connected to the base. The pressure frame is provided with an elastic membrane. When the pressure frame is rotated to a closed position in a closing direction, the elastic membrane abuts against the closed surface and restricts the movement of the tissue sample in the cavity in the closing direction. A movable bracket is slidably connected to the pressure frame. There are at least two movable brackets, and the sliding trajectories of the movable brackets do not overlap. The outer wall of the pressure frame is provided with several travel grooves, the number of which is at least two. The movable bracket is slidably connected to the travel grooves and slides along the extension direction of the travel grooves. The movement trajectory of the movable support along the second travel groove is a straight line segment, and adjacent second travel grooves are not parallel to each other; Alternatively, the movement trajectory of the movable support along the second travel groove is circular, so that the movable support slides along the second travel groove while rotating around an axis, and the axis around which the movable support rotates extends in the closed direction and coincides with the center of the second travel groove. The movable support is provided with a travel groove, and the travel groove of the adjacent movable support has a central positioning channel along the closing direction when the pressure frame moves to the closed position. A movable block is slidably connected to the movable support, and the movable block is provided with an edge positioning channel through it; When the pressure frame moves to the closed position, the extension directions of the center positioning channel and the edge positioning channel coincide with the closing direction, so that the center positioning channel and the edge positioning channel form a projection on the elastic membrane along the closing direction.

2. The tissue positioning disc according to claim 1, characterized in that, Each of the movable supports is slidably connected to at least two movable blocks, allowing the edge positioning channels of each movable block to project onto multiple locations of the elastic membrane along the closing direction as it slides along the moving movable support.

3. The tissue positioning disc according to claim 2, characterized in that, The movable support includes a crossbeam and legs that are fixedly connected. The first travel groove is provided on the crossbeam, and the end of the leg away from the crossbeam is slidably connected to the second travel groove.

4. The tissue positioning disc according to claim 3, characterized in that, The movable support also includes an elastic element one, and the outer wall of the pressure frame is provided with a limiting groove. During the process of the movable support being inserted into the travel groove two in the closing direction, the elastic element one is squeezed and deformed against the outer wall of the pressure frame. After the movable support moves to a mating position, the elastic element one is inserted into the limiting groove towards the end of the pressure frame and elastically resets, so as to restrict the movement of the movable support in the closing direction or the opposite direction of the closing direction. The limiting groove and the travel groove two correspond one-to-one and are parallel to each other.

5. The tissue positioning disc according to claim 4, characterized in that, The first elastic element is an elastic plate. When the first elastic element is not subjected to external force, its end away from the support leg does not contact the support leg. When the first elastic element contacts the pressure frame and they are pressed against each other, the first elastic element deforms and its end in contact with the pressure frame moves away from the support leg, so that when the first elastic element moves to the mating position, it moves toward the support leg and abuts against the outer wall of the pressure frame.

6. The tissue positioning disc according to claim 1, characterized in that, The movable block includes a block body with an edge positioning channel running through it and two elastic elements. The elastic elements are fixedly connected to the block body. When the movable block is slidably connected to the movable support, the end of the elastic element away from the block body abuts against the end of the movable support away from the block body to restrict the movable block from moving in the closing direction or the opposite direction of the closing direction.

7. The tissue positioning disc according to claim 1, characterized in that, The cavity wall of the receiving cavity is provided with several threaded holes, which open into the outer wall of the base; each threaded hole is connected to a positioning bolt, and when the positioning bolt rotates around its own axis, the length of the portion of the positioning bolt extending into the receiving cavity changes; the central axes of adjacent positioning bolts are not parallel to each other.

8. The tissue positioning disc according to claim 1, characterized in that, The pressure frame has an operating area that extends through it, and the operating area is aligned with the receiving cavity along the closing direction.

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