Portable mouse tissue experiment device

Abstract

The invention provides a portable mouse tissue experimental device, and particularly relates to the technical field of experimental equipment.The portable mouse tissue experimental device comprises a separating device, the separating device comprises a first annular component and a suture line, a plurality of circular holes are formed in the side wall of the first annular component, and the suture line is arranged in the circular holes; according to the invention, the mouse is separated and fixed by using the suture line, and the anesthetized mouse is matched with the suture line of different circular holes through different mice, so that the skin or muscle of all places of the mouse can be separated and fixed; and a target tissue area can be better, rapidly, completely and safely exposed.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of experimental equipment, in particular to a portable mouse tissue experimental device. BACKGROUND

[0002] It is of great significance to develop new models of low back pain to explore the mechanism of low back pain for clinical and basic research of low back pain. At present, the models of low back pain mainly include lumbar disc puncture and resection model, injection of inflammatory mediators in the tissue around the lumbar vertebrae model, and physical compression of the lumbar nerve root model.

[0003] However, no matter which model needs to completely expose the intervertebral disc, and the intervertebral disc surgery is performed by microsurgery. Since the intervertebral disc is located deep, it is easy to damage the internal organs and nerves during the exposure of the intervertebral disc. Therefore, how to expose the intervertebral disc completely, quickly and safely is very important, which is related to the success rate of the operation. SUMMARY

[0004] In order to solve the problem that the experimental device cannot expose the intervertebral disc quickly, safely and completely, the present application provides a portable mouse tissue experimental device.

[0005] The present application is realized by the following technical solutions: The present application provides a portable mouse tissue experimental device, which comprises a separation device, the separation device comprises a first annular member and a suture, a plurality of circular holes are arranged on the side wall of the first annular member, the suture passes through the circular holes and fixes and separates the experimental sample.

[0006] Further, it further comprises a magnifying and illuminating device, which is aligned with the separation device from the top of the separation device.

[0007] Further, the magnifying and illuminating device comprises a second annular member and a convex lens, the convex lens is arranged inside the second annular member and is fixedly connected with the second annular member.

[0008] Further, the magnifying and illuminating device further comprises a plurality of LED lamp modules, the plurality of LED lamp modules are arranged at the bottom edge of the convex lens and are fixed to the bottom of the second annular member.

[0009] Further, it further comprises an adjusting device, the adjusting device comprises a base, a stand is arranged on the base, a first knob slot and a second knob slot are arranged on the stand, and the first knob slot and the second knob slot are connected with a first horizontal rod and a second horizontal rod respectively.

[0010] Further, one end of the first horizontal rod is connected with the first annular member through a first connecting rod.

[0011] Further, the second ring-shaped member is connected with the second cross bar through a second connecting rod.

[0012] Advantages of the present application: (1) The portable mouse tissue experimental device separates and fixes the mouse by using sutures. After anesthesia, the mouse is separated and fixed by sutures with different circular holes, so that the skin or muscle of the mouse can be separated and fixed, and the target tissue area can be better exposed quickly, completely and safely.

[0013] (2) The portable mouse tissue experimental device uses a magnifying illumination device for magnifying illumination, avoiding the traditional observation of experimental samples under a microscope. The device is more compact, lightweight and convenient. BRIEF DESCRIPTION OF DRAWINGS

[0014] Fig. 1 is a structural diagram of the portable mouse tissue experimental device of the present application; Fig. 2 is a structural diagram of the separation device of the portable mouse tissue experimental device of the present application; Fig. 3 is a structural diagram of the magnifying illumination device of the portable mouse tissue experimental device of the present application; In the figure: separation device 1, first ring-shaped member 11, circular hole 12, suture 13, magnifying illumination device 2, second ring-shaped member 21, convex lens 22, LED lamp module 23, adjusting device 3, vertical rod 31, second cross bar 32, first cross bar 33, second knob clamping groove 34, first knob clamping groove 45, base 36, first connecting rod 37, second connecting rod 38, The purpose, functional characteristics and advantages of the present application will be further described with reference to the embodiments and the accompanying drawings. DETAILED DESCRIPTION

[0015] In order to more clearly and completely illustrate the technical solutions of the present application, the present application will be further described below with reference to the accompanying drawings.

[0016] Please refer to Figs. 1-3 The present application provides a portable mouse tissue experimental device including a separation device 1, the separation device 1 including a first ring-shaped member 11 and a suture 13, the sidewall of the first ring-shaped member 11 being provided with a plurality of circular holes 12, the circular holes 12 being used for passing through the suture 13, the suture 13 passing through the circular holes 12 and fixing and separating the experimental sample.

[0017] In the specific embodiment, the first annular member 11 is circular, and a plurality of annular holes are arranged on the side wall, and the suture 13 passes through the annular holes and passes through the skin or muscle of the mouse in the middle, so as to fix the mouse, facilitate the exposure of the intervertebral disc, peripheral afferent nerve and other positions of the mouse, and the suture 13 of the different circular holes 12 can be matched with the different mice after the mouse is anesthetized, so as to separate and fix the skin or muscle of all places of the mouse, and better expose the target tissue area quickly, completely and safely.

[0018] Further, the magnifying and illuminating device 2 is arranged on the top of the separating device 1.

[0019] In the specific embodiment, the magnifying and illuminating device 2 is used for magnifying and illuminating the experimental sample, so as to facilitate subsequent experimental operation.

[0020] Further, the magnifying and illuminating device 2 comprises a second annular member 21 and a convex lens 22, and the convex lens 22 is arranged in the second annular member 21 and is fixedly connected with the second annular member 21.

[0021] In the specific embodiment, the second annular member 21 is arranged above the first annular member 11 and is aligned with the first annular member 11, and the convex lens 22 is used for magnifying and observing the experimental sample.

[0022] Further, the magnifying and illuminating device 2 further comprises a plurality of LED lamp modules 23, and the plurality of LED lamp modules 23 are arranged at the bottom edge of the convex lens 22 and are fixed to the bottom of the second annular member 21.

[0023] In the specific embodiment, the LED lamp modules 23 are arranged around the convex lens 22 and are used for illuminating the experimental sample.

[0024] Further, the adjusting device 3 comprises a base 36, a vertical rod 31 arranged on the base 36, a first knob slot 45 and a second knob slot 34 arranged on the vertical rod 31, a first horizontal rod 33 and a second horizontal rod 32 connected with the first knob slot 45 and the second knob slot 34 respectively, a first connecting rod 37 connected between one end of the first horizontal rod 33 and the first annular member 11, and a second connecting rod 38 connected between the second annular member 21 and the second horizontal rod 32.

[0025] In the specific embodiment, the base 36 can be used for placing the experimental sample, the vertical rod 31 connected with the base 36 is used for adjusting the position between the magnifying and illuminating device 2 and the separating device 1, and the first knob slot 45 and the second knob slot 34 can be used for adjusting the height and length of the first horizontal rod 33 and the second horizontal rod 32, so as to change the position of the illuminating device and the separating device 1.

[0026] As shown above, when the mouse intervertebral disc exposure experiment is performed, due to the unique position of the intervertebral disc (back muscle and visceral tissue wrapping), it is easy to damage other tissues when exposing the intervertebral disc, and it may even cause the mouse to bleed a lot, so it is necessary to avoid tissue damage during the operation process. The mouse after anesthesia is placed on the base 36, and then the skin and muscle of the mouse abdomen are cut. Since the skin and muscle have resilience, they will block the exposure of the deep intervertebral disc, so the suture 13 is passed through the skin and muscle, and then it is tied on the circular hole 12, so that the skin and muscle can be stretched to expose the intervertebral disc tissue. The visceral tissue attached to the muscle around the intervertebral disc can also be pulled by the suture 13, which can well avoid tissue damage. At the same time, combined with the illumination magnifying device, the intervertebral disc position can be accurately and quickly exposed without damage, which is convenient for subsequent experimental operation. The same is true for the experiment of recording the signal of the afferent nerve. The suture 13 is passed through the skin and muscle, and the skin and muscle are stretched to expose the afferent nerve fiber. The nerve signal recording device is connected to the outside for nerve signal collection. During the collection of the nerve electrical signal, the stability of the mouse needs to be maintained, and the nerve fiber needs to be exposed sufficiently and cannot damage other tissues. The separation device 1 and the magnifying illumination device 2 can achieve this goal.

[0027] Of course, the present application can have other various embodiments. Based on the present embodiment, other embodiments obtained by those skilled in the art without any creative labor belong to the scope of protection of the present application.

Claims

1. A portable mouse tissue experiment device, characterized by, The device comprises a separation device, which comprises a first ring-shaped member and a suture, a plurality of circular holes are arranged on the sidewall of the first ring-shaped member, the suture passes through the circular holes and fixes and separates the experimental sample.

2. The portable mouse tissue lab device of claim 1, wherein, The device further comprises a magnifying illumination device, which is aligned with the separation device from the top of the separation device.

3. The portable mouse tissue lab device of claim 2, wherein, The magnifying illumination device comprises a second ring-shaped member and a convex lens, which is arranged inside the second ring-shaped member and fixedly connected with the second ring-shaped member.

4. The portable mouse tissue lab device of claim 3, wherein, The magnifying illumination device further comprises a plurality of LED lamp modules, which are arranged at the bottom edge of the convex lens and fixed to the bottom of the second ring-shaped member.

5. The portable mouse tissue lab device of claim 2, wherein, The device further comprises an adjusting device, which comprises a base, a vertical rod arranged on the base, a first knob slot and a second knob slot arranged on the vertical rod, and a first horizontal rod and a second horizontal rod connected with the first knob slot and the second knob slot respectively.

6. The portable mouse tissue lab device of claim 5, wherein, One end of the first horizontal rod is connected with the first ring-shaped member through a first connecting rod.

7. The portable mouse tissue lab device of claim 6, wherein, The second ring-shaped member is connected with the second horizontal rod through a second connecting rod.

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