Traditional Chinese medicine composition for treating impotence and premature ejaculation as well as preparation method and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating impotence and premature ejaculation as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 130 parts of rhizoma curculiginis, 130 parts of herba epimedii, 180 parts of Chinese chive seeds, 250 parts of fructus lycii, 240 parts of rhizoma dioscoreae, 10 parts of mantis egg-case, 120 parts of semen cuscutae, 100 parts of fructus corni and 100 parts of herba cynomorii. In the formula, rhizoma curculiginis, herba epimedii and cynomorium songaricum are used as monarch drugs to greatly tonify kidney yang The semen cuscutae, the Chinese chive seeds and the mantis egg-case are used as ministerial drugs to help the monarch drugs to warm the kidney and also have the effects of securing essence and reducing urination; the fructus lycii and the pulp of dogwood fruit are used for nourishing yin and boosting essence, so that yang is assisted by yin and is endless; chinese yam can tonify spleen and induce astringency, and can nourish the congenital. The whole formula has the effects of invigorating kidney and strengthening Yang, boosting essence and securing essence, and strengthening spleen and inducing astringency.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine, and more particularly to a traditional Chinese medicine composition for treating impotence and premature ejaculation, and a preparation method and application thereof. BACKGROUND

[0002] Kidney yang deficiency is a common syndrome in traditional Chinese medicine, especially in young and middle-aged men, which is usually caused by overwork, kidney deficiency in the elderly, and long-term illness. The main clinical manifestations are sexual dysfunction (such as impotence, premature ejaculation, and spermatorrhea), soreness and cold pain in the waist and knees, aversion to cold and cold limbs, mental debilitation, clear urine or frequent nocturia, etc., which seriously affect the quality of life and physical and mental health of patients.

[0003] At present, traditional Chinese medicine decoction or Chinese patent medicine is commonly used to treat kidney yang deficiency. Although classical prescriptions such as Yougui Pill and Jinkui Shenqi Pill have certain effects, there are still some deficiencies: first, some prescriptions have a relatively severe medicinal property or are greasy, and long-term use may cause burden on the function of spleen and stomach; second, the common prescriptions need to be improved in terms of the specificity for the reproductive function problems caused by kidney deficiency; third, the traditional decoction is inconvenient to decoct and has poor taste, and the patient compliance is low.

[0004] In addition, the processing method of traditional Chinese medicinal materials is directly related to the exertion of medicinal effect and the reduction of toxic and side effects. For example, although Herba Rhizoma Typhonii has the function of tonifying kidney yang, improper processing may easily cause adverse reactions such as swelling of the mouth and tongue; through specific processing methods (such as oil frying and salt frying), medicinal materials such as Herba Epimedii and Semen Trichosanthis can be introduced into the meridian, significantly enhancing their effects of warming and tonifying kidney yang and astringing essence and restraining urine. However, there is a lack of a comprehensive scheme in the prior art for the systematic and standardized processing of multiple medicinal materials to maximize the synergistic effect and reduce toxicity, and to prepare a convenient preparation.

[0005] Therefore, it is an urgent problem for those skilled in the art to provide a traditional Chinese medicine composition for treating kidney yang deficiency, which has a reasonable prescription, a unique processing technology, significant efficacy, and is convenient to take. SUMMARY

[0006] In view of the above, the present application provides a traditional Chinese medicine composition for treating impotence and premature ejaculation, and a preparation method and application thereof.

[0007] In order to achieve the above-mentioned purpose, the present application adopts the following technical solutions: A traditional Chinese medicine composition for treating impotence and premature ejaculation comprises the following components in parts by weight: 130 parts of Herba Rhizoma Typhonii, 130 parts of Herba Epimedii, 180 parts of Semen Allii Tuberosi, 250 parts of Fructus Lycii, 240 parts of Rhizoma Dioscoreae, 10 parts of Armigeres leucocelaenus, 120 parts of Semen Trichosanthis, 100 parts of Fructus Corni, and 100 parts of Herba Cynomorii.

[0008] A preparation method of a traditional Chinese medicine composition for treating impotence and premature ejaculation comprises the following steps: S1 The processing of Curculigo orchioides: take clean Curculigo orchioides, soak it in the rice washing water of glutinous rice, replace it with fresh rice washing water every day, and soak it for 7 days. Take it out and dry it for standby; Glutinous rice itself has the effects of tonifying middle energizer and invigorating spleen and stomach. In the processing process, the characteristics of glutinous rice can interact with Curculigo orchioides, not only reducing toxicity, but also enhancing the kidney yang tonifying effect of Curculigo orchioides while taking into account the transportation and transformation function of the spleen and stomach, so that the human body can better absorb and utilize the medicinal effect of Curculigo orchioides, thereby improving the overall treatment effect on the basis of ensuring the safety of medication.

[0009] S2 The processing of Herba Epimedii: take clean Herba Epimedii, and prepare 5g of mutton tail oil for every 25g of Herba Epimedii; heat the mutton tail oil to 50℃, and put it into Herba Epimedii. Stir-fry it at 50-60℃ for 3 minutes to make all the leaves evenly immersed in the oil, and then take it out and cool it down for standby; Herba Epimedii itself has the effects of tonifying kidney yang, strengthening bones and muscles, and dispelling wind and dampness. Mutton tail oil is a fatty oil obtained from the tail of sheep, which is warm in nature and has the effects of tonifying kidney and providing energy. Stir-frying Herba Epimedii with mutton tail oil can enhance the warm and tonifying effect of Herba Epimedii on kidney yang, and has a better therapeutic effect on impotence, premature ejaculation, soreness of waist and knees, cold limbs and other symptoms caused by deficiency of kidney yang.

[0010] S3 The processing of Allium tuberosum seeds: take clean Allium tuberosum seeds, put them in an oil-free iron pan, and stir-fry them at 120-150℃ for 10 minutes until they are cooked. Take them out and cool them down for standby; Stir-frying can change the nature of Allium tuberosum seeds, making their warm nature more gentle, persistent and more targeted. After stir-frying, the warm and tonifying effect of Allium tuberosum seeds on the kidney can be better exerted, and they can more accurately act on the pathological state of deficiency of kidney yang in the human body, enhancing the effect of warming the kidney and assisting yang.

[0011] S4 The processing of Astragalus testa: take clean Astragalus testa, put it in the remaining mutton tail oil from the stir-frying of Herba Epimedii in step S2, add 2g of edible salt, and stir-fry it at 50-80℃ until the surface is slightly yellow. Take it out and cool it down for standby; Salt is salty and cold in nature, and has the characteristic of entering the kidney. Astragalus testa itself has the effects of tonifying kidney and assisting yang, and astringing essence and reducing urine. It is mainly used for the treatment of premature ejaculation, frequent urination, leukorrhea and other symptoms caused by deficiency of the kidney. After salt frying, it can guide the drug downward, enhance the effect of Astragalus testa on the kidney, make its kidney tonifying effect more specific and significant, and more accurately act on the kidney, thereby better exerting the treatment of symptoms related to the kidney.

[0012] S5 The processing of Semen Leonuri: take clean Semen Leonuri, mix it with 2g of edible salt water, and soak it until the salt water is absorbed. Put it in a preheated frying container, heat it at 120-150℃, and take it out when it is slightly puffed, has a popping sound, and emits a fragrance. Cool it down for standby; The semen cuscutae can lead the medicine into the kidney and enhance the effects of tonifying kidney and benefiting essence, and the salt can enter the kidney channel, so the semen cuscutae processed with salt water can make the medicine enter the kidney channel, and the treatment effect on kidney deficiency diseases such as lumbago, impotence, spermatorrhea, frequent urination and incontinence is more obvious.

[0013] S6 Other medicinal material processing: take medlar, yam, dogwood meat, and cynomorium, clean and dry them for later use; S7 Mixing and grinding: mix all the medicinal materials processed in steps S1-S6 evenly, and use a cold water grinder to grind them at low temperature to obtain fine powder, and then pass the fine powder through an 80-120 mesh sieve to obtain the traditional Chinese medicine composition.

[0014] The purpose is to ensure the activity of the medicinal material components in the environment of the cold water grinder low-temperature grinding, so that the traditional Chinese medicine can better play its therapeutic effect in the subsequent use process and maintain the stability of the medicinal effect.

[0015] The application of a traditional Chinese medicine composition for treating impotence and premature ejaculation in the preparation of a medicine for treating kidney deficiency, wherein the symptoms of the kidney deficiency include impotence, premature ejaculation, spermatorrhea, decreased sexual function, lumbago and knee soreness, frequent nocturia, and lack of energy.

[0016] Further, the medicine includes traditional Chinese medicine water pills or traditional Chinese medicine honey pills. The raw materials of the traditional Chinese medicine honey pills are the traditional Chinese medicine composition powder and honey, and the mass ratio is 1:1-1.5.

[0017] According to the above technical solution, compared with the prior art, the beneficial effects of the present application are: The prescription is scientific, and the monarch, minister, assistant and guide are clear: in the prescription, the herba rhizomatis, epimedium and cynomorium are the monarch, which greatly tonifies kidney yang; the semen cuscutae, leek seeds and ground snail are the minister, which not only assists the monarch in warming the kidney, but also has the effect of astringing essence and shrinking urine; the medlar and dogwood meat are used as the assistant to nourish yin and essence, so that yang is assisted by yin and is endless in transformation; the yam strengthens the spleen and astringes, and takes care of the acquired constitution to nourish the congenital constitution. The whole prescription can tonify the kidney, strengthen yang, benefit essence and astringe essence, and strengthen the spleen and astringe.

[0018] The processing technology is unique, and the efficacy is increased and the toxicity is reduced: the herba rhizomatis is soaked in water to remove its toxicity, the epimedium is fried with goat tail oil to enhance the effect of warming the kidney, the ground snail and semen cuscutae are salted to lead the medicine into the kidney channel, and the leek seeds are fried to moderate the drug property and enhance the warming and tonifying effect. The unique processing method greatly stimulates the efficacy of the medicinal materials and ensures the safety of the medicine.

[0019] The curative effect is remarkable: tonifying the kidney, strengthening yang, benefiting essence and astringing essence, and strengthening the spleen and astringing; treating warming and tonifying kidney yang, improving impotence, premature ejaculation, cold pain in the waist and knees, cold aversion, and low sexual function; nourishing yin and essence, tonifying liver and kidney, benefiting essence and filling marrow, improving essence deficiency, dizziness, tinnitus, fatigue, astringing essence and shrinking urine; reducing spermatorrhea, frequent urination, and improving the problem of urination; strengthening the muscles and bones, enhancing the body strength, improving the soreness of the waist and knees, and improving the energy and endurance; improving the immunity, resisting fatigue, and improving the sub-health state; As shown in the following examples, the present composition has a significant effect on improving the manifestations of kidney yang deficiency, such as impotence, premature ejaculation, spermatorrhea, decreased sexual function, soreness of the waist and knees, and lack of energy, especially on sexual function and reproductive problems, and has a relatively fast onset time.

[0020] Advanced dosage form, easy to take: using low-temperature crushing technology to make fine powder, which maximizes the retention of bioactive ingredients of medicinal materials, and is easy to carry and take, with high patient compliance. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present application will be described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application. Example 1

[0022] Preparation of the traditional Chinese medicine composition The raw materials are weighed as follows: 130g of Xianmao, 130g of Yinyanghe, 180g of Jiecaizi, 250g of Gouqizi, 240g of Shanyao, 10g of Tangkui, 120g of Tusizi, 100g of Shanyurou, and 100g of Suoyang.

[0023] Then, the following steps are taken for processing and processing: Processing Xianmao: Take 3 kg of rice washing water, and soak Xianmao in a basin. Place it in a cool place and replace it with fresh rice washing water every day for a total of 7 days. Take it out, rinse it with clean water, and dry it for use.

[0024] Processing Yinyanghe: Weigh 5g of mutton tail oil. Preheat the pot, add mutton tail oil, and heat to 55±5℃. Put in 25g of Yinyanghe, immediately turn to small fire, and quickly stir-fry for 3 minutes to ensure that all the leaves are soaked with mutton tail oil. Take out and spread to cool.

[0025] Processing Jiecaizi: Place Jiecaizi in a clean, oil-free iron pot, heat to 130±5℃ on a small fire, and stir-fry for 10 minutes until the aroma is released and the color of the seeds is deepened. Take out and cool for use.

[0026] Processing Tangkui: In the oil pot for processing Yinyanghe (remaining mutton tail oil), add 2g of edible salt, and immediately put in Tangkui. Heat to 60±5℃ and stir-fry for about 2-3 minutes until the surface color is slightly yellow. Take out and cool for use.

[0027] Processing Semen Momordicae: 2g of salt is dissolved in an appropriate amount of water to make a salt solution. Mix the salt solution with Semen Momordicae and soak for about 1-2 hours until the salt solution is completely absorbed. Preheat a pot, pour in Semen Momordicae, and heat on low heat to 130±5℃. Stir-fry until most of the seeds have slightly puffed up, with surface cracks, darkened to yellow-brown or brown, and a strong medicinal aroma. Most of the seeds will crackle and pop slightly, then remove from the pot and cool down to prevent burning.

[0028] Processing other medicinal materials: clean and dry the selected Fructus Lycii, Rhizoma Dioscoreae, Fructus Corni, and Herba Cynomorii, and remove impurities.

[0029] Mixing and grinding: mix all the processed medicinal materials evenly. Put them into a cold water grinder and grind in a low-temperature 5℃ environment. The obtained fine powder is sieved through a 100-mesh sieve and sealed for packaging, thus obtaining the finished product of the traditional Chinese medicine composition.

[0030] Example 2: Observation of clinical effects To verify the effects of the traditional Chinese medicine composition, 35 male patients who met the diagnostic criteria for kidney yang deficiency (main symptoms: impotence, premature ejaculation, spermatorrhea, low libido, soreness of the waist and knees, and frequent nocturia) were observed. The patients were aged 25-65 years, with an average age of 42 years. They took 9g of the fine powder prepared in Example 1 twice a day, and washed it down with warm water. After continuous use for one month, the results were as follows: Case 1: Kong, male, 25 years old. Due to high work pressure, he suffered from severe impotence and premature ejaculation, and the relationship with his wife was tense. He started taking the fine powder of the traditional Chinese medicine composition in June 2012. After one week, he felt that his energy had improved, and his morning erection had recovered. After three months of continuous use, his sexual function completely returned to normal.

[0031] Case 2: Feng, male, 38 years old. An electric welder, he suffered from impotence, premature ejaculation, and erectile dysfunction for two years. He started taking the product in March 2018, and after two weeks, his symptoms improved significantly. After more than two months of continuous use, his sexual function returned to normal, and he was highly satisfied.

[0032] Case 3: Shi, male, 56 years old. He had been suffering from perennial cold limbs, frequent nocturia (3-4 times a night), and impotence. He started taking the product in July 2015, and after one month, his symptoms of cold and nocturia were alleviated. After five months, all his symptoms had basically disappeared, and he had abundant energy.

[0033] Case 4: Wang, male, 40 years old. He was infertile due to low sperm viability. After taking the fine powder of the traditional Chinese medicine composition for five months in 2005, his sperm viability improved significantly. His wife later became pregnant, and they now have one son and one daughter.

[0034] Case 5: Liu, male, 62 years old. He was old and had kidney deficiency, soreness of the waist and knees, and frequent nocturia. After three months of treatment, his waist and knees were stronger, his nocturia frequency was reduced to 1-2 times, and his mental state improved significantly.

[0035] The above results show that the traditional Chinese medicine composition provided by the present application has the characteristics of accurate curative effect and comprehensive effect on kidney yang deficiency and various symptoms caused thereby, has high total effective rate, and has no obvious adverse reactions.

[0036] The above description of disclosed embodiments enables one of ordinary skill in the art to make or use the application. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein can be applied to other embodiments without departing from the spirit or scope of the application. Thus, the present application is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A traditional Chinese medicine composition for treating impotence and premature ejaculation, characterized in that, By weight parts, including the following components: 130 parts of Herba Rhizomatis, 130 parts of Herba Epimedii, 180 parts of Allium victorialis L. seed, 250 parts of Fructus Lycii, 240 parts of Rhizoma Dioscoreae, 10 parts of Pheretima, 120 parts of Semen Cannabis, 100 parts of Fructus Corni, 100 parts of Herba Cynomorii. ​ 2. The preparation method of the traditional Chinese medicine composition according to claim 1, characterized in that, Including the following steps: S1 processing of Herba Rhizomatis: take clean Herba Rhizomatis, soak in glutinous rice water, replace with fresh glutinous rice water every day, a total of 7 days, take out and dry for standby; S2 processing of Herba Epimedii: take clean Herba Epimedii, 5g of mutton tail oil for every 25g of Herba Epimedii; heat the mutton tail oil to 50℃, put in Herba Epimedii, stir-fry at 50-60℃ for 3 minutes, so that all the leaves are evenly immersed in the oil, take out and cool for standby; S3 processing of Allium victorialis L. seed: take clean Allium victorialis L. seed, put in an oil-free iron pan, stir-fry at 120-150℃ for 10 minutes until cooked, take out and cool for standby; S4 processing of Pheretima: take clean Pheretima, put in the remaining mutton tail oil from the step S2 of stir-frying Herba Epimedii, add 2g of edible salt, stir-fry at 50-80℃ until the surface is slightly yellow, take out and cool for standby; S5 processing of Semen Cannabis: take clean Semen Cannabis, mix with 2g of edible salt, soak until the salt water is absorbed, put in a preheated frying container, heat at 120-150℃, fry until slightly puffed, with a popping sound, and aromatic gas escaping, take out and cool for standby; S6 processing of other medicinal materials: take Fructus Lycii, Rhizoma Dioscoreae, Fructus Corni and Herba Cynomorii, dry for standby after cleaning; S7 mixing and grinding: mix all the medicinal materials processed in steps S1-S6 evenly, use a cold water grinder to grind at low temperature 0-10℃, get fine powder, pass through 80-120 mesh sieve, get the traditional Chinese medicine composition.

3. The application of the traditional Chinese medicine composition of claim 1 in the preparation of a medicine for treating kidney deficiency, the symptoms of kidney deficiency including impotence, premature ejaculation, spermatorrhea, decreased sexual function, soreness of the waist and knees, frequent nocturia and lack of energy.

4. Use according to claim 3, characterized in that, The medicine includes traditional Chinese medicine water pills or traditional Chinese medicine honey pills; The raw materials of the traditional Chinese medicine honey pills are the traditional Chinese medicine composition powder and honey, the mass ratio being 1:1-1.5.