Cornea collagen crosslinking negative pressure suction promoting instrument
By designing a negative pressure aspiration device, the problems of riboflavin solution loss and inaccurate dripping during corneal collagen cross-linking surgery have been solved, achieving stable penetration and safe dripping of riboflavin, thus improving surgical outcomes and patient comfort.
Patent Information
- Application Number
- CN202511332151.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-18
- Publication Date
- 2026-01-02
AI Technical Summary
In traditional corneal collagen cross-linking surgery, riboflavin solution is difficult to apply stably to the cornea and is prone to leakage. Furthermore, the hand-held application method causes tremors and affects the structure of the eyeball, impacting accuracy and safety.
A corneal collagen crosslinking negative pressure adsorption device was designed, which uses a negative pressure device and a disposable auxiliary cup. The piston assembly is driven by the negative pressure button to create a negative pressure environment, allowing the riboflavin solution to penetrate the corneal stroma under the siphon effect. Combined with the pneumatic system to adjust the pressure, the device ensures sealing and comfort.
This method achieves stable permeation of riboflavin solution, avoids loss and waste, improves the accuracy and safety of dripping, enhances therapeutic effects, and improves patient comfort.
Smart Images
Figure CN121242825A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of ophthalmic surgical instruments, in particular to a corneal collagen cross-linking negative pressure promoting instrument. BACKGROUND
[0002] Corneal collagen cross-linking surgery is an effective method for treating keratoconus and other corneal diseases, which prevents or delays the progression of corneal lesions by enhancing the mechanical strength of the cornea. During the operation, riboflavin is used as a photosensitizer to induce chemical cross-linking reaction of corneal collagen fibers under ultraviolet irradiation, thereby increasing the hardness and stability of the cornea.
[0003] In traditional corneal collagen cross-linking surgery, riboflavin solution needs to be continuously added to the cornea, which can easily cause riboflavin solution to flow away from the cornea surface, not easily penetrate into the corneal stroma, and easily cause waste. Secondly, for the method of adding riboflavin in the stainless steel ethanol solution cover by hand, the hand of the medical staff is easy to shake after a long time of holding, which not only affects the accurate addition of riboflavin, but also can cause riboflavin to flow out of the cup body. In addition, when the medical staff presses the cup body onto the cornea of the eyeball, it may cause certain impact on the internal structure of the eyeball.
[0004] Therefore, it is necessary to provide a corneal collagen cross-linking negative pressure promoting instrument to solve the above problems. SUMMARY
[0005] The technical problem solved by the present application is to provide a corneal collagen cross-linking negative pressure promoting instrument to solve the problem that in the existing corneal collagen cross-linking surgery, riboflavin solution needs to be continuously added to the cornea, which can easily cause riboflavin solution to flow away from the cornea surface, not easily penetrate into the corneal stroma, and easily cause waste. Secondly, for the method of adding riboflavin in the stainless steel ethanol solution cover by hand, the hand of the medical staff is easy to shake after a long time of holding, which not only affects the accurate addition of riboflavin solution, but also can cause riboflavin solution to flow out of the cover. In addition, when the medical staff presses the cup body onto the cornea of the eyeball, it may cause certain impact on the internal structure of the eyeball.
[0006] Technical solution: To achieve the above object, the application is realized by the following technical solutions: A corneal collagen cross-linking negative pressure promoting suction instrument, comprising a negative pressure device and a disposable auxiliary cup, the disposable auxiliary cup comprises a cylindrical cup body and a fixing ring closely fitted with the eyeball, the fixing ring is fixedly sleeved on the lower end of the cup body; the negative pressure device comprises a shell, a negative pressure assembly, a pressure relief assembly and a negative pressure pipe arranged in the shell, one end of the negative pressure pipe extends out of the shell and is detachably connected with the fixing ring; the negative pressure assembly comprises a plurality of air cylinders I fixedly installed in the shell, a piston I is slidably sleeved in the air cylinder I, a push rod I is fixedly installed on the top of the piston I, the upper end of the push rod I penetrates through the shell and is fixedly installed with a negative pressure button; a spring I is sleeved in the air cylinder I below the piston I, an exhaust pipe and an air suction pipe are fixedly installed at the bottom of the air cylinder I and communicate with the inside thereof; the pressure relief assembly comprises a plurality of air cylinders II fixedly installed in the shell, the air cylinders II correspond to the air cylinders I one by one, two limiting rings are fixedly sleeved in the air cylinder II in the vertical direction, and the two limiting rings separate the air cylinder II into upper, middle and lower three chambers; a piston II is slidably sleeved in the middle chamber, a spring II is sleeved in the lower chamber, a push rod II is fixedly installed on the top of the piston II, the upper end of the push rod II penetrates through the shell and is fixedly installed with a pressure relief button, a channel I and a channel II are formed in the piston II, and the channel I and the channel II are both L-shaped; an air inlet is formed in the side wall of the lower chamber, the exhaust pipe communicates with the upper chamber, the air suction pipe communicates with the bottom of the middle chamber, a communication pipe is fixedly installed at the top of the middle chamber and communicates with the inside thereof, and the other end of the communication pipe communicates with the negative pressure pipe.
[0007] Preferably, the negative pressure device further comprises an isolation tank, the top of the fixing ring is fixedly installed with a connecting pipe communicating with the inside thereof, one end of the connecting pipe away from the fixing ring is detachably installed with an air filtering assembly, and the two ends of the air filtering assembly are detachably installed with the isolation tank and the negative pressure pipe respectively.
[0008] Preferably, the middle part of the fixing ring is convex to the side away from the eyeball, so that an annular cavity is formed between the fixing ring and the eyeball, one end of the connecting pipe communicates with the annular cavity, the cylindrical cup body, the fixing ring and the connecting pipe are integrally formed, and the air filtering assembly comprises a shell and a filter membrane arranged in the shell.
[0009] Preferably, the push rod I and the push rod II are both hexagonal prisms, a plurality of hexagonal through holes are formed in the top of the shell, the upper ends of the push rod I and the push rod II both extend out of the shell through the corresponding through holes, a plurality of suction cups are fixedly installed at the bottom of the shell, and the plurality of suction cups are arranged in a rectangular shape.
[0010] Preferably, the negative pressure device further comprises a power supply fixedly installed in the shell, indicator lights fixedly installed on the top of the shell, a control panel and a power switch, and a position sensor arranged on the shell below the negative pressure button, the indicator lights are multiple, the multiple indicator lights correspond one-to-one to the negative pressure assemblies, the negative pressure tube is provided with a pressure sensor, the indicator lights, the control panel, the power switch, the position sensor and the pressure sensor are electrically connected with the power supply, and the indicator lights, the position sensor and the pressure sensor are in control connection with the control panel.
[0011] Beneficial effects: compared with the prior art, the present application provides a corneal collagen cross-linking negative pressure suction instrument, which has a unique structure and is easy to use, adopts a pneumatic negative pressure system, drives a piston assembly to form a negative pressure environment by pressing a negative pressure button, makes a fixed ring of a disposable auxiliary cup closely fit the corneal surface to form a closed treatment space, at this time, riboflavin solution can be stably accumulated in the cup body, and under the combined action of siphon effect and corneal surface tension, continuously penetrates the stroma layer, avoids solution loss in the traditional dropwise addition mode, and the double air cylinder design has negative pressure generation and pressure regulation functions, when the negative pressure value exceeds the patient's tolerance threshold, the local pressure can be accurately released through the pressure relief button, while ensuring the treatment effect, the comfort is improved. BRIEF DESCRIPTION OF DRAWINGS
[0012] Figure 1 is a schematic view of the structure of the present application; Figure 2 is a schematic view of the structure of the present application; Figure 3 is a schematic view of the structure of the present application; Figure 4 is a schematic view of the structure of the present application; Figure 5 is a schematic view of the structure of the present application; Figure 6 is a schematic view of the structure of the present application; Figure 7 is a schematic view of the structure of the present application; Figure 6 is a schematic view of the structure of the present application; Figure 8 is a schematic view of the structure of the present application; Figure 9 is a schematic view of the structure of the present application;
[0013] In the diagram: 1. Negative pressure device; 11. Housing; 12. Indicator light; 13. Control panel; 14. Power switch; 15. Negative pressure assembly; 151. Air cylinder I; 152. Piston I; 153. Exhaust pipe; 154. Intake pipe; 155. Spring I; 156. Push rod I; 157. Negative pressure button; 16. Pressure relief assembly; 161. Air cylinder II; 162. Piston II; 163. Channel I; 164. Air inlet; 165. Spring II; 166. Limiting ring; 167. Push rod II; 168. Pressure relief button; 169. Channel II; 1610. Connecting pipe; 17. Negative pressure pipe; 18. Isolation tank; 19. Suction cup; 2. Disposable auxiliary cup; 21. Cup body; 22. Fixing ring; 23. Connecting pipe; 24. Air filter assembly. Detailed Implementation
[0014] The present invention will be further described below with reference to the accompanying drawings and embodiments.
[0015] Example 1: This Example 1 provides a corneal collagen cross-linking negative pressure suction device with a unique structure. Please refer to [link / reference]. Figures 1-7 As shown, the negative pressure device 1 and the disposable auxiliary cup 2 are included. The disposable auxiliary cup 2 includes a cylindrical cup body 21 and a fixing ring 22 that fits tightly against the eyeball. The fixing ring 22 is fixedly fitted to the lower end of the cup body 21. The negative pressure device 1 includes a housing 11 and a negative pressure component 15, a pressure relief component 16 and a negative pressure tube 17 disposed inside the housing 11. One end of the negative pressure tube 17 extends out of the housing 11 and is detachably connected to the fixing ring 22. The negative pressure device 1 also includes an isolation tank 18. A connecting pipe 23 communicating with the inside of the fixing ring 22 is fixedly installed on the top of the fixing ring 22. An air filter component 24 is installed at the end of the connecting pipe 23 away from the fixing ring 22 through a Luer lock connector. Both ends of the air filter component 24 are detachably installed to the isolation tank 18 and the negative pressure tube 17 through Luer lock connectors.
[0016] The middle part of the fixing ring 22 protrudes away from the eyeball, forming an annular cavity between the fixing ring 22 and the eyeball. One end of the connecting tube 23 is connected to the annular cavity. The cylindrical cup 21, the fixing ring 22, and the connecting tube 23 are integrally formed. The air filter assembly 24 includes a housing and a filter membrane disposed within the housing. The isolation tank 18 can prevent tears and riboflavin solution from entering the negative pressure tube 17. Through the insert design, it is not only convenient to replace the disposable auxiliary cup 2, but also convenient to clean the isolation tank 18. There are various choices for the filter membrane, such as polypropylene (PP) filter membrane and polytetrafluoroethylene (PTFE) filter membrane. In this solution, a polypropylene (PP) filter membrane is selected. By setting the polypropylene (PP) filter membrane, tears and riboflavin solution can pass through, while the air entering the fixing ring 22 during depressurization can be filtered to prevent dust, bacteria, and other impurities from entering the eyes.
[0017] The negative pressure assembly 15 includes multiple air cylinders I 151 fixedly installed inside the housing 11. A piston I 152 is slidably fitted inside the air cylinder I 151. A push rod I 156 is fixedly installed on the top of the piston I 152. The upper end of the push rod I 156 passes through the housing 11 and is fixedly installed with a negative pressure button 157. A spring I 155 is fitted inside the air cylinder I 151 below the piston I 152. An exhaust pipe 153 and an intake pipe 154 communicating with the bottom of the air cylinder I 151 are fixedly installed. The pressure relief assembly 16 includes multiple air cylinders II 161 fixedly installed inside the housing 11. 61 corresponds one-to-one with air cylinder I 151. Two limiting rings 166 are fixedly installed vertically along the inside of air cylinder II 161, which divides air cylinder II 161 into three chambers: upper, middle and lower. Piston II 162 is slidably installed in the middle chamber, and spring II 165 is installed in the lower chamber. Push rod II 167 is fixedly installed on the top of piston II 162. The upper end of push rod II 167 passes through the outer shell 11 and is fixedly installed with pressure relief button 168. Channel I 163 and channel II 169 are opened inside piston II 162, and both channel I 163 and channel II 169 are L-shaped.
[0018] An air inlet 164 is provided on the side wall of the lower chamber, an exhaust pipe 153 is connected to the upper chamber, an intake pipe 154 is connected to the bottom of the middle chamber, and a connecting pipe 1610 connected to the interior of the middle chamber is fixedly installed on the top of the middle chamber. The other end of the connecting pipe 1610 is connected to the negative pressure pipe 17. In the initial state, piston II 162 abuts against the limiting ring 166 on the upper part of air cylinder II 161. At this time, exhaust pipe 153 is connected to connecting pipe 1610 through channel II 169. When piston II 162 abuts against the limiting ring 166 on the lower part of air cylinder II 161, suction pipe 154 is connected to the external environment through channel I 163 and air inlet 164. Push rod I 156 and push rod II 167 are both hexagonal prisms. Multiple hexagonal through holes are opened on the top of the outer shell 11. The upper ends of push rod I 156 and push rod II 167 extend out of the outer shell 11 through the corresponding through holes, so that piston I 152 and piston II 162 can only slide vertically. Multiple suction cups 19 are fixedly installed on the bottom of the outer shell 11. The multiple suction cups 19 are arranged in a rectangle. By setting suction cups 19, the outer shell 11 can be firmly attached to the operating table.
[0019] Working principle: When medical staff perform corneal cross-linking surgery, they first place the disposable auxiliary cup 2 directly onto the cornea, aligning the center of the cup 21 with the center of the cornea. Then, they connect the air filter assembly 24, the isolation canister 18, and the negative pressure tube 17 through the Luer lock connector. Pressing one of the negative pressure buttons 157 causes the piston I 152 to move downward. At this time, the air below the piston I 152 is discharged from the fixing ring 22 through the exhaust pipe 153, channel II 169, connecting pipe 1610, negative pressure tube 17, isolation canister 18, and connecting pipe 23. Then, releasing the negative pressure button 157 causes the piston I 152 to move upward under the action of the spring I 155, thereby extracting the gas from the cavity between the fixing ring 22 and the eyeball, so that the fixing ring 22 is firmly attached to the eyeball under the action of negative pressure.
[0020] Then, the riboflavin solution can be dripped into the cup 21. Since the inner side of the fixing ring 22 is attached to the eyeball, the seal between the disposable auxiliary cup 2 and the eyeball is enhanced. Therefore, after the riboflavin liquid is dripped onto the corneal surface inside the cup, it will accumulate on the corneal surface and penetrate into the corneal stroma over time. Only one addition is needed to complete the full penetration of riboflavin into the cornea, avoiding waste of riboflavin. In addition, since the cup 21 has a certain height, the riboflavin can better penetrate into the corneal stroma under pressure. Furthermore, when performing negative pressure adsorption, it can be flexibly adjusted according to the patient's tolerance. Multiple negative pressure buttons 157 can be pressed at the same time to enhance the adsorption capacity.
[0021] When the negative pressure is too high and the patient cannot tolerate it, press the pressure relief buttons 168 corresponding to the negative pressure button 157 one by one. When the piston II 162 contacts the limiting ring 166 at the bottom of the air cylinder II 161, the channel II 169 and the connecting pipe 1610 are misaligned, and one end of the channel I 163 is connected to the inhalation pipe 154. At this time, external air enters the inhalation pipe 154 through the air inlet 164 and returns the air pressure in the air cylinder I 151 below the piston I 152 to the initial state. At this time, the spring I 155 pushes the corresponding piston I 152 back to the initial position. When the medical staff releases the pressure relief button 168, the channel II 169 and the connecting pipe 1610 are reconnected, thereby reducing the negative pressure between the fixing ring 22 and the eyeball until the patient can tolerate it.
[0022] Example 2: The difference between Example 2 and Example 1 is as follows: Figure 1As shown, the negative pressure device 1 also includes a power supply fixedly installed inside the housing 11, an indicator light 12 fixedly installed on the top of the housing 11, a control panel 13 and a power switch 14, and a position sensor located on the housing 11 below the negative pressure button 157. There are multiple indicator lights 12, and each indicator light 12 corresponds to a negative pressure component 15. A pressure sensor is installed inside the negative pressure tube 17. The indicator lights 12, control panel 13, power switch 14, position sensor and pressure sensor are all electrically connected to the power supply. The indicator lights 12, position sensor and pressure sensor are all controlled and connected to the control panel 13.
[0023] Indicator light 12, control panel 13, power switch 14, position sensor, and pressure sensor are all existing devices. Their internal structure and working principle will not be described in detail. By setting indicator light 12, control panel 13, position sensor, and pressure sensor, when the bottom of negative pressure button 157 contacts the position sensor, the position sensor transmits a signal to control panel 13. Control panel 13 controls the corresponding indicator light 12 to light up, so that staff can better observe how many negative pressure buttons 157 have moved down. When the fixation ring 22 is attached to the patient's eyeball under the action of negative pressure, the pressure sensor can transmit the pressure signal to control panel 13 and display the specific pressure value on control panel 13, so that medical staff can more accurately understand the negative pressure in the cavity between fixation ring 22 and eyeball.
[0024] Example 3: The difference between Example 3 and Example 1 is as follows: Figures 8-9 As shown, in order to further improve the adsorption capacity of the disposable auxiliary cup 2, the degree of protrusion in the middle of the fixing ring 22 can be increased, so that a tubular cavity is formed between the fixing ring 22 and the eyeball.
[0025] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A corneal collagen cross-linking negative pressure suction device, comprising a negative pressure device (1) and a disposable auxiliary cup (2), characterized in that: The disposable auxiliary cup (2) includes a cylindrical cup body (21) and a fixing ring (22) that fits tightly against the eyeball. The fixing ring (22) is fixedly fitted to the lower end of the cup body (21). The negative pressure device (1) includes a housing (11) and a negative pressure component (15), a pressure relief component (16), and a negative pressure tube (17) disposed within the housing (11). One end of the negative pressure tube (17) extends out of the housing (11) and is detachably connected to the fixing ring (22). The negative pressure component (15) includes components fixedly installed within the housing (11). Multiple air cylinders I (151) are provided. A piston I (152) is slidably fitted inside each air cylinder I (151). A push rod I (156) is fixedly installed on the top of the piston I (152). The upper end of the push rod I (156) penetrates the outer casing (11) and is fixedly fitted with a negative pressure button (157). A spring I (155) is fitted inside the air cylinder I (151) below the piston I (152). An exhaust pipe (153) and an intake pipe (154) communicating with the bottom of the air cylinder I (151) are fixedly installed. The pressure relief assembly (16) includes... Multiple air cylinders II (161) are fixedly installed inside the outer casing (11). Each air cylinder II (161) corresponds to an air cylinder I (151). Two limiting rings (166) are fixedly fitted inside each air cylinder II (161) at vertical intervals. The two limiting rings (166) divide the air cylinder II (161) into three chambers: upper, middle, and lower. A piston II (162) is slidably fitted in the middle chamber, and a spring II (165) is fitted in the lower chamber. A push rod II (167) is fixedly installed on the top of the piston II (162), and the upper end of the push rod II (167) passes through... The outer shell (11) is fixedly installed with a pressure relief button (168). The piston II (162) has a channel I (163) and a channel II (169) inside, and both channels I (163) and channel II (169) are L-shaped. The side wall of the lower chamber has an air inlet (164). The exhaust pipe (153) is connected to the upper chamber. The suction pipe (154) is connected to the bottom of the middle chamber. The top of the middle chamber is fixedly installed with a connecting pipe (1610) that is connected to its interior. The other end of the connecting pipe (1610) is connected to the negative pressure pipe (17).
2. The corneal collagen cross-linking negative pressure suction device according to claim 1, characterized in that: The negative pressure device (1) also includes an isolation tank (18), and a connecting pipe (23) communicating with the inside of the fixing ring (22) is fixedly installed on the top of the fixing ring (22). An air filter assembly (24) is detachably installed at one end of the connecting pipe (23) away from the fixing ring (22). The two ends of the air filter assembly (24) are detachably installed together with the isolation tank (18) and the negative pressure pipe (17) respectively.
3. The corneal collagen cross-linking negative pressure suction device according to claim 2, characterized in that: The middle part of the fixing ring (22) protrudes away from the eyeball, so that the fixing ring (22) and the eyeball form an annular cavity. One end of the connecting tube (23) is connected to the annular cavity. The cylindrical cup (21), the fixing ring (22) and the connecting tube (23) are integrally formed. The air filter assembly (24) includes a housing and a filter membrane disposed in the housing.
4. The corneal collagen cross-linking negative pressure suction device according to claim 1, characterized in that: Both push rod I (156) and push rod II (167) are hexagonal prisms. Multiple hexagonal through holes are provided on the top of the outer shell (11). The upper ends of push rod I (156) and push rod II (167) extend out of the outer shell (11) through the corresponding through holes. Multiple suction cups (19) are fixedly installed on the bottom of the outer shell (11). The multiple suction cups (19) are arranged in a rectangular pattern.
5. The corneal collagen cross-linking negative pressure suction device according to claim 1, characterized in that: The negative pressure device (1) also includes a power supply fixedly installed inside the housing (11), an indicator light (12) fixedly installed on the top of the housing (11), a control panel (13) and a power switch (14), and a position sensor set on the housing (11) below the negative pressure button (157). There are multiple indicator lights (12), and each indicator light (12) corresponds to a negative pressure component (15). A pressure sensor is provided inside the negative pressure tube (17). The indicator light (12), control panel (13), power switch (14), position sensor and pressure sensor are all electrically connected to the power supply. The indicator light (12), position sensor and pressure sensor are all controlled and connected to the control panel (13).