Biocompatible antibacterial and detoxicating water paint and preparation method thereof

Abstract

The invention relates to a biocompatible antibacterial and detoxicating water paint and a preparation method thereof, and belongs to the technical field of antibacterial and detoxicating materials. According to the formula, the antibacterial and detoxifying water paint is prepared from, by weight, 30-50 parts of waterborne polyurethane emulsion, 0.1-0.2 part of an antibacterial and detoxifying auxiliary, 0.3-0.5 part of panthenol, 0.2-0.3 part of citrus peel extract, 0.05-0.1 part of a pH regulator, 0.05-0.1 part of liquiritigenin and 50-60 parts of deionized water, zinc serves as an inner core of the antibacterial and detoxifying auxiliary, a zinc oxide shell layer is generated outwards in situ, then the zinc oxide shell layer is compounded with tea polyphenol, and the antibacterial and detoxifying water paint is prepared. And jointly loading on the activated Na-montmorillonite. The antibacterial and detoxicating water paint prepared by the invention has excellent biocompatibility and long-acting antibacterial and detoxicating effects.

Description

Technical Field

[0001] This invention belongs to the field of antibacterial and detoxifying materials technology, and relates to a biocompatible antibacterial and detoxifying water-based paint and its preparation method. Background Technology

[0002] With increasing public health awareness and growing public health and safety demands, the market demand for surface coating materials with antibacterial and antiviral functions has surged. These materials are widely used in home environments, medical facilities, public transportation, and educational institutions, aiming to reduce the risk of cross-contamination of microorganisms through surface treatment technology.

[0003] Currently, mainstream antibacterial and antiviral coatings on the market are mainly based on the following technologies, but all have limitations to varying degrees. For example, while silver and copper ion-based inorganic metal ion antibacterial coatings have long-lasting antibacterial properties, they face challenges in practical applications such as easy particle aggregation, potential safety risks, and limited functionality. Titanium dioxide photocatalytic antibacterial coatings typically require ultraviolet light to generate active oxygen to decompose microorganisms; however, the photocatalytic process may accelerate the aging of the coating itself, affecting its durability. Plant essential oil-based coatings, while less irritating, face problems such as limited antibacterial efficacy, complex and unstable composition, and inability to provide sustained antibacterial effects.

[0004] Therefore, there is an urgent need to develop an antibacterial and detoxifying water-based paint with excellent and long-lasting antibacterial and detoxifying effects, as well as excellent biocompatibility. Summary of the Invention

[0005] The purpose of this invention is to provide a biocompatible antibacterial and detoxifying water-based paint and its preparation method, which has excellent biocompatibility and antibacterial and detoxifying effects.

[0006] The objective of this invention can be achieved through the following technical solutions: A biocompatible antibacterial and detoxifying water-based paint, wherein the antibacterial and detoxifying water-based paint formulation is as follows (by weight): 30-50 parts water-based polyurethane emulsion, 0.1-0.2 parts antibacterial and detoxifying adjuvant, 0.3-0.5 parts panthenol, 0.2-0.3 parts citrus peel extract, 0.05-0.1 parts pH adjuster, 0.05-0.1 parts glycyrrhizin, and 50-60 parts deionized water. The preparation method of the antibacterial and detoxifying adjuvant is as follows: S1-1: Add zinc powder to zinc chloride solution, then heat to 80~100 ℃, add sodium hydroxide solution dropwise and stir continuously for 20~60 min, centrifuge, wash and dry the obtained solid product to obtain zinc core powder; S1-2: Add sodium montmorillonite to deionized water, sonicate for 15-30 min, add 1-5% dilute sulfuric acid, stir at 55-65 ℃ for 1-2 h, filter, wash with deionized water until pH is neutral, dry, pulverize and pass through a 200-mesh sieve to obtain pretreated sodium montmorillonite. S1-3: Mix zinc nucleus powder with tea polyphenols and add to deionized water. Stir for 30-60 min, add pretreated sodium montmorillonite, stir at 40-50 ℃ for 10-30 min, adjust pH to 8.5-9.5 with sodium hydroxide solution, raise temperature to 60-80 ℃ and continue stirring for 1-2 h, then freeze dry for 12 h to obtain the antibacterial and detoxifying adjuvant.

[0007] As a preferred embodiment of the present invention, the pH adjuster is one or more of tannic acid, lactic acid, and citric acid.

[0008] As a preferred embodiment of the present invention, the molar ratio of zinc powder added in S1-1 to zinc element in zinc chloride solution is (0.5~1.5):1, and the molar ratio of sodium hydroxide to zinc chloride is (3~4):1.

[0009] As a preferred embodiment of the present invention, the ultrasonic power in S1-2 is 200~400 W.

[0010] As a preferred embodiment of the present invention, in step S1-3, zinc nucleus powder and tea polyphenols are mixed at a mass ratio of 1:(1~2).

[0011] As a preferred embodiment of the present invention, the mass ratio of sodium-based montmorillonite to zinc core powder in S1-3 is (3~5):1.

[0012] As a preferred embodiment of the present invention, the freeze-drying temperature in S1-3 is -30~-40 ℃.

[0013] A method for preparing a biocompatible antibacterial and detoxifying water-based paint, the specific steps of which are as follows: S8-1: Add deionized water to the material tank according to the formula ratio, add panthenol at a speed of 150~250 rpm, stir for 10~20 min, add antibacterial and detoxifying adjuvant powder, homogenize for 5~10 min, and then perform ultrasonic treatment for 10~15 min with an ultrasonic power of 200~300 W. S8-2: Adjust the rotation speed to 600~700 rpm, add citrus peel extract and glycyrrhizin to the material tank in sequence, continue stirring for 10~30 min, then add water-based polyurethane emulsion dropwise, keep stirring for 10~30 min, finally add pH adjuster, stir for 10~30 min, filter through 200~300 mesh filter cloth, and then let stand and mature in the dark for 10~16 h to obtain the biocompatible antibacterial and detoxifying water-based paint.

[0014] As a preferred embodiment of the present invention, the homogenization rotation speed in S8-1 is 8000~10000 rpm.

[0015] As a preferred embodiment of the present invention, in step S8-2, a pH adjuster is used to adjust the pH to 5.5~6.5.

[0016] Pretreatment of sodium-based montmorillonite with dilute sulfuric acid under ultrasonic assistance can exfoliate montmorillonite layers, increase its specific surface area, and generate some diatomaceous earth or amorphous silica structures with stronger adsorption activity. The activated montmorillonite has a strong adsorption and fixation capacity for bacterial endotoxins, heavy metal ions, virus particles, and odor molecules, achieving an organic combination of physical detoxification and chemical antibacterial properties.

[0017] Zinc cores and tea polyphenols are pre-assembled in solution. Pretreated montmorillonite, with its large specific surface area and ion exchange capacity, loads and anchors the zinc core-tea polyphenol complex onto its lamellar structure and surface through van der Waals forces, hydrogen bonds, and ionic bonds. The montmorillonite carrier effectively blocks direct contact between the nano-zinc core particles, solving the problems of easy aggregation and deactivation of nanomaterials and ensuring the stability of the product during storage. During action, the montmorillonite-loaded structure can slowly release the zinc core-tea polyphenol complex, avoiding a one-time burst release, thus providing long-lasting antibacterial protection. Compared with ordinary drying, freeze-drying can prevent the collapse and aggregation of nanostructures, maintain the porous structure and high specific surface area of ​​the material, and maximize its antibacterial adsorption activity.

[0018] The zinc nucleus powder combined with tea polyphenols forms an inorganic-organic synergistic antibacterial system. The zinc nucleus destroys bacterial cell membranes by releasing zinc ions and generating reactive oxygen species. Tea polyphenols then penetrate the damaged cell membranes, denature proteins, and disrupt microbial metabolism. This multi-target, continuous attack mode enables the adjuvant to have highly efficient and broad-spectrum inactivation capabilities against bacteria, fungi, and even enveloped viruses, significantly reducing the risk of microbial resistance.

[0019] Waterborne polyurethane forms a dense, elastic film through molecular chain cross-linking, which can firmly adhere to the substrate surface, serving as a carrier for antibacterial and detoxifying ingredients, preventing rapid loss due to friction or rinsing, and prolonging the action time. Waterborne polyurethane uses water as the dispersion medium and contains no organic solvents, avoiding the cytotoxicity of traditional solvent-based polyurethanes and meeting safety requirements. When combined with antibacterial and detoxifying additives, the film layer can slowly release active ingredients, achieving sustained-release antibacterial effects; synergistically with panthenol and citrus peel extract, it enhances moisturizing effects. Panthenol has nourishing, repairing, and moisturizing properties, and can enhance the surface flexibility of materials.

[0020] Citrus peel extract possesses natural antibacterial and odor-regulating properties, while also improving the cleanliness of material surfaces. Containing active ingredients such as limonene and hesperidin, citrus peel extract achieves antibacterial effects by disrupting bacterial cell membranes and inhibiting energy metabolism, and is also effective against drug-resistant bacteria. The synergistic effect of citrus peel extract and tea polyphenols significantly enhances the inhibitory effect on mold on substrate surfaces. Limonene, as a natural solvent, can dissolve oil and adhesive stains on substrate surfaces without damaging the substrate. The natural citrus aroma masks the odors of other ingredients, improving the product's user experience, and its low volatility results in minimal residue.

[0021] Glycyrrhizin can inhibit the activity of inflammatory enzymes such as COX-2 and 5-LOX, reduce prostaglandin synthesis, and work synergistically with tea polyphenols and citrus peel extracts to target bacterial cell membranes, enhancing its inhibitory effect on Gram-positive bacteria. It is particularly effective for addressing odor problems on leather surfaces caused by bacterial growth. Glycyrrhizin is a flavonoid compound, chemically stable, does not react with the substrate, and can reduce UV-induced aging of plastics or fading of wood.

[0022] The beneficial effects of this invention are: In the preparation of the antibacterial and detoxifying adjuvant of this invention, sodium-based montmorillonite is first pretreated with dilute sulfuric acid using ultrasound to increase its specific surface area and generate a highly adsorbent active structure, achieving a combination of physical detoxification and chemical antibacterial action. Zinc cores and tea polyphenols are pre-assembled and anchored by the pretreated montmorillonite, solving the problem of nanomaterial aggregation and inactivation, ensuring storage stability, and providing long-lasting antibacterial protection through slow release. Freeze-drying preserves its antibacterial adsorption activity. The zinc core powder and tea polyphenols form an inorganic-organic synergistic antibacterial system, targeting multiple sites and continuously attacking bacteria, fungi, and enveloped viruses with high efficiency and broad-spectrum inactivation, significantly reducing the risk of microbial resistance. In the formulation, waterborne polyurethane emulsion serves as a carrier for the antibacterial components and enhances surface flexibility and gloss. Glycyrrhizin, citrus peel extract, and other ingredients further synergistically enhance antibacterial activity and improve biocompatibility, resulting in a final product with excellent and long-lasting antibacterial and detoxifying effects, as well as excellent biocompatibility. Detailed Implementation

[0023] To further illustrate the technical means and effects of the present invention in achieving its intended purpose, the following detailed description of the specific implementation methods, structures, features, and effects of the present invention, in conjunction with embodiments, is provided below.

[0024] It should be noted that, unless otherwise specified, the present invention does not specifically limit the source of the raw materials used in the following embodiments. Commercially available products or products prepared by conventional preparation methods that are well known to those skilled in the art can be used. Experimental methods that do not specify specific conditions are all conventional methods and conventional conditions well known in the art.

[0025] Example 1 A biocompatible antibacterial and detoxifying water-based paint, the formulation of which is as follows (by weight): 40 parts waterborne polyurethane emulsion, 0.15 parts antibacterial and detoxifying additive, 0.4 parts panthenol, 0.25 parts citrus peel extract, 0.08 parts tannic acid, 0.08 parts glycyrrhizin, and 55 parts deionized water. The preparation method of the antibacterial and detoxifying adjuvant is as follows: S1-1: Add zinc powder to zinc chloride solution, then heat to 90 °C, add sodium hydroxide solution dropwise and stir continuously for 40 min. The molar ratio of zinc powder added to zinc element in zinc chloride solution is 1:1, and the molar ratio of sodium hydroxide to zinc chloride is 3.5:1. Centrifuge, wash and dry the obtained solid product to obtain zinc core powder. S1-2: Sodium-based montmorillonite was added to deionized water and ultrasonically treated for 20 min at an ultrasonic power of 300 W. 3% dilute sulfuric acid of equal volume to deionized water was added and stirred at 60 °C for 1.5 h. After filtration, it was washed with deionized water until the pH was neutral. After drying, it was crushed and passed through a 200-mesh sieve to obtain pretreated sodium-based montmorillonite. S1-3: Zinc core powder and tea polyphenols were mixed at a mass ratio of 1:1.5 and added to deionized water. The mixture was stirred for 45 min. Pretreated sodium montmorillonite was added, with a mass ratio of sodium montmorillonite to zinc core powder of 4:1. The mixture was stirred at 45 °C for 20 min. The pH was adjusted to 9 with sodium hydroxide solution, and the temperature was raised to 70 °C. The mixture was stirred for 1.5 h and then freeze-dried at -35 °C for 12 h to obtain the antibacterial and detoxifying adjuvant.

[0026] A method for preparing a biocompatible antibacterial and detoxifying water-based paint, the specific steps of which are as follows: S8-1: Add deionized water to the material tank according to the formula ratio, add panthenol at 200 rpm, stir for 15 min, add antibacterial and detoxifying adjuvant powder, homogenize for 8 min at 9000 rpm, and then perform ultrasonic treatment for 12 min at an ultrasonic power of 250 W. S8-2: Adjust the rotation speed to 650 rpm, add citrus peel extract and glycyrrhizin to the material tank in sequence, continue stirring for 20 min, then add water-based polyurethane emulsion dropwise, keep stirring for 20 min, finally add tannic acid to adjust the pH to 6, stir for 20 min, filter through a 250-mesh filter cloth, and then let it stand and mature in the dark for 13 h to obtain the biocompatible antibacterial and detoxifying water-based paint.

[0027] Example 2 A biocompatible antibacterial and detoxifying water-based paint, the formulation of which is as follows (by weight): 30 parts water-based polyurethane emulsion, 0.1 parts antibacterial and detoxifying additive, 0.3 parts panthenol, 0.2 parts citrus peel extract, 0.05 parts citric acid, 0.05 parts glycyrrhizin, and 50 parts deionized water. The preparation method of the antibacterial and detoxifying adjuvant is as follows: S1-1: Add zinc powder to zinc chloride solution, then heat to 80 °C, add sodium hydroxide solution dropwise and stir continuously for 20 min. The molar ratio of zinc powder added to zinc element in zinc chloride solution is 0.5:1, and the molar ratio of sodium hydroxide to zinc chloride is 3:1. Centrifuge, wash and dry the obtained solid product to obtain zinc core powder. S1-2: Sodium montmorillonite was added to deionized water and ultrasonically treated for 15 min at an ultrasonic power of 200 W. 1% dilute sulfuric acid of the same volume as deionized water was added and stirred at 55 °C for 1 h. After filtration, it was washed with deionized water until the pH was neutral. After drying, it was crushed and passed through a 200-mesh sieve to obtain pretreated sodium montmorillonite. S1-3: Zinc core powder and tea polyphenols are mixed at a mass ratio of 1:1 and added to deionized water. The mixture is stirred for 30 min, and then pretreated sodium montmorillonite is added. The mass ratio of sodium montmorillonite to zinc core powder is 3:1. The mixture is stirred at 40℃ for 10 min, and the pH is adjusted to 8.5 with sodium hydroxide solution. The temperature is then raised to 60℃ and stirred for 1 h. Finally, the mixture is freeze-dried at -30℃ for 12 h to obtain the antibacterial and detoxifying adjuvant.

[0028] A method for preparing a biocompatible antibacterial and detoxifying water-based paint, the specific steps of which are as follows: S8-1: Add deionized water to the material tank according to the formula ratio, add panthenol at 150 rpm, stir for 10 min, add antibacterial and detoxifying adjuvant powder, homogenize for 5 min at 8000 rpm, and then perform ultrasonic treatment for 10 min at an ultrasonic power of 200 W. S8-2: Adjust the rotation speed to 600 rpm, add citrus peel extract and glycyrrhizin to the material tank in sequence, continue stirring for 10 min, then add water-based polyurethane emulsion dropwise, keep stirring for 10 min, finally add citric acid to adjust the pH to 5.5, stir for 10 min, filter through a 200-mesh filter cloth, and then let it stand and mature in the dark for 10 h to obtain the biocompatible antibacterial and detoxifying water-based paint.

[0029] Example 3 A biocompatible antibacterial and detoxifying water-based paint, the formulation of which is as follows (by weight): 50 parts water-based polyurethane emulsion, 0.2 parts antibacterial and detoxifying additive, 0.5 parts panthenol, 0.3 parts citrus peel extract, 0.1 parts citric acid, 0.1 parts glycyrrhizin, and 60 parts deionized water. The preparation method of the antibacterial and detoxifying adjuvant is as follows: S1-1: Add zinc powder to zinc chloride solution, then heat to 100 °C, add sodium hydroxide solution dropwise and stir continuously for 60 min. The molar ratio of zinc powder added to zinc element in zinc chloride solution is 1.5:1, and the molar ratio of sodium hydroxide to zinc chloride is 4:1. Centrifuge, wash and dry the obtained solid product to obtain zinc core powder. S1-2: Sodium montmorillonite was added to deionized water and ultrasonically treated for 30 min at an ultrasonic power of 400 W. 5% dilute sulfuric acid of equal volume to deionized water was added and stirred at 65 °C for 2 h. After filtration, it was washed with deionized water until the pH was neutral. After drying, it was crushed and passed through a 200-mesh sieve to obtain pretreated sodium montmorillonite. S1-3: Zinc core powder and tea polyphenols were mixed at a mass ratio of 1:2 and added to deionized water. The mixture was stirred for 60 min, and then pretreated sodium montmorillonite was added. The mass ratio of sodium montmorillonite to zinc core powder was 5:1. The mixture was stirred at 50 °C for 30 min, and the pH was adjusted to 9.5 with sodium hydroxide solution. The temperature was then raised to 80 °C and stirred for 2 h. Finally, the mixture was freeze-dried at -40 °C for 12 h to obtain the antibacterial and detoxifying adjuvant.

[0030] A method for preparing a biocompatible antibacterial and detoxifying water-based paint, the specific steps of which are as follows: S8-1: Add deionized water to the material tank according to the formula ratio, add panthenol at 250 rpm, stir for 20 min, add antibacterial and detoxifying adjuvant powder, homogenize for 10 min at 10000 rpm, and then perform ultrasonic treatment for 15 min at an ultrasonic power of 300 W. S8-2: Adjust the rotation speed to 700 rpm, add citrus peel extract and glycyrrhizin to the material tank in sequence, continue stirring for 30 min, then add water-based polyurethane emulsion dropwise, keep stirring for 30 min, finally add citric acid to adjust the pH to 6.5, stir for 30 min, filter through a 300-mesh filter cloth, and then let it stand and mature in the dark for 16 h to obtain the biocompatible antibacterial and detoxifying water-based paint.

[0031] Comparative Example 1 In the preparation of the antibacterial and detoxifying adjuvant, commercially available zinc oxide is used instead of zinc core powder, and the remaining steps are the same as in Example 1.

[0032] Comparative Example 2 The preparation of the antibacterial and detoxifying adjuvant does not involve pretreatment of sodium montmorillonite; the remaining steps are the same as in Example 1.

[0033] Comparative Example 3 The preparation of the antibacterial and detoxifying adjuvant does not involve the addition of tea polyphenols, and the remaining steps are the same as in Example 1.

[0034] Comparative Example 4 The preparation of the antibacterial and detoxifying water-based paint does not involve the addition of citrus peel extract, and the remaining steps are the same as in Example 1.

[0035] Comparative Example 5 The preparation of the antibacterial and detoxifying water-based paint does not involve the addition of glycyrrhizin, and the remaining steps are the same as in Example 1.

[0036] Antibacterial performance test The antibacterial properties of the products prepared according to the HG / T 3950-2007 standard examples and comparative examples were tested, with Escherichia coli and Staphylococcus aureus used as experimental bacteria, respectively.

[0037]

[0038] Antibacterial durability The antibacterial durability of the products prepared according to the HG / T 3950-2007 standard examples and comparative examples was tested. Escherichia coli was used as the experimental bacteria. The test conditions were as follows: a 30W ultraviolet lamp with a wavelength of 253.7nm was used, the lamp was 0.8m away from the sample, and the lamp was irradiated for 100h.

[0039]

[0040] Antiviral performance test The antiviral performance of the products prepared according to the T / CNCIA 01014-2020 standard test examples and comparative examples was evaluated, using influenza A virus H1N1 as the experimental virus.

[0041]

[0042] Purification Experiment of Gaseous Pollutants According to the QB / T 2761-2024 standard, test the formaldehyde removal rate of Example 1. Apply the sample evenly three times on 3 pieces of 1 m 2 base paper. After air drying naturally, place it in a 1.5m 3 test chamber for detection and calculate the formaldehyde removal rate.

[0043]

[0044] Guinea Pig Skin Sensitization Experiment Test substance: Take 0.5 g of the sample prepared in Example 1, apply it on two layers of gauze of 2.5 cm × 2.5 cm, and place it at room temperature to air dry naturally as the test substance.

[0045] Experimental animals: Albino guinea pigs, half male and half female, with a body weight range of 300 - 500 g, animal certificate number: 430730251100166185. The experimental animals are provided by Hunan Zhongke Gene Technology Co., Ltd. (production license number of experimental animals: SCXK(Xiang)2023 - 0011). Feeding environment: Temperature is 20 - 26 °C, relative humidity is 30 - 70%.

[0046] Test procedure: 1. Inductive contact: Depilate the left side of the back of the experimental animals 24 h before the test, with a depilation area of 3 cm × 3 cm. Take 2.5 cm × 2.5 cm of the test substance, directly apply it on the 3 cm × 3 cm depilated area on the left side of the test animals, cover it with two layers of gauze and one layer of non - irritating plastic film, and then seal and fix it with non - irritating tape for 6 h. After that, remove any closed - type tying fixatives and patches. Repeat this step continuously for 3 days in 1 week. Operate in the same way for 3 weeks.

[0047] 2. Eliciting contact: On the 14th day after the last induction, take 2.5 cm × 2.5 cm of the test substance, directly apply it on the 3 cm × 3 cm depilated area on the right side of the test animals, cover it with two layers of gauze and one layer of non - irritating plastic film, and then seal and fix it with non - irritating tape for 6 h. After that, remove any closed - type tying fixatives and patches.

[0048] 3. The treatment method of the negative control is the same as that of the test area. Do not make any treatment during inductive contact, and apply the test substance during eliciting contact. The positive control uses 2,4 - dinitrochlorobenzene as the test substance, and the treatment method is the same as that of the test area.

[0049] Results evaluation: After 24 hours of stimulation, the stimulation site and surrounding hair were shaved, thoroughly washed with warm water and dried for 2 hours, and scored according to the Magnusson and Kligman grading criteria. Scoring was performed again 48 hours after removal. Sensitization was considered when the control group grade was <1 and the test substance grade was >1.

[0050]

[0051] As can be seen from the above embodiments and comparative data, the water-based paint prepared by the present invention has excellent biocompatibility and long-lasting antibacterial and detoxifying effects.

[0052] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make some modifications or alterations to the above-disclosed technical content to create equivalent embodiments without departing from the scope of the present invention. Any simple modifications, equivalent changes and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention are still within the scope of the present invention.

Claims

1. A biocompatible antibacterial and detoxifying water-based paint, characterized in that, The antibacterial and detoxifying water-based paint formulation is as follows (by weight): 30-50 parts water-based polyurethane emulsion, 0.1-0.2 parts antibacterial and detoxifying additive, 0.3-0.5 parts panthenol, 0.2-0.3 parts citrus peel extract, 0.05-0.1 parts pH adjuster, 0.05-0.1 parts glycyrrhizin, and 50-60 parts deionized water. The preparation method of the antibacterial and detoxifying adjuvant is as follows: S1-1: Add zinc powder to zinc chloride solution, then heat to 80~100 ℃, add sodium hydroxide solution dropwise and stir continuously for 20~60 min, centrifuge, wash and dry the obtained solid product to obtain zinc core powder; S1-2: Add sodium montmorillonite to deionized water, sonicate for 15-30 min, add 1-5% dilute sulfuric acid, stir at 55-65 ℃ for 1-2 h, filter, wash with deionized water until pH is neutral, dry, pulverize and pass through a 200-mesh sieve to obtain pretreated sodium montmorillonite. S1-3: Mix zinc nucleus powder with tea polyphenols and add to deionized water. Stir for 30-60 min, add pretreated sodium montmorillonite, stir at 40-50 ℃ for 10-30 min, adjust pH to 8.5-9.5 with sodium hydroxide solution, raise temperature to 60-80 ℃ and continue stirring for 1-2 h, then freeze dry for 12 h to obtain the antibacterial and detoxifying adjuvant.

2. The biocompatible antibacterial and detoxifying water-based paint according to claim 1, characterized in that, The pH adjuster is one or more of tannic acid, lactic acid, and citric acid.

3. The biocompatible antibacterial and detoxifying water-based paint according to claim 1, characterized in that, The molar ratio of zinc powder added in S1-1 to zinc element in zinc chloride solution is (0.5~1.5):1, and the molar ratio of sodium hydroxide to zinc chloride is (3~4):

1.

4. The biocompatible antibacterial and detoxifying water-based paint according to claim 1, characterized in that, The ultrasonic power in S1-2 is 200~400 W.

5. The biocompatible antibacterial and detoxifying water-based paint according to claim 1, characterized in that, In step S1-3, zinc nucleus powder and tea polyphenols are mixed at a mass ratio of 1:(1~2).

6. The biocompatible antibacterial and detoxifying water-based paint according to claim 1, characterized in that, The mass ratio of sodium-based montmorillonite to zinc core powder in S1-3 is (3~5):

1.

7. The biocompatible antibacterial and detoxifying water-based paint according to claim 1, characterized in that, The freeze-drying temperature in S1-3 is -30~-40 ℃.

8. A method for preparing a biocompatible antibacterial and detoxifying water-based paint as described in any one of claims 1 to 7, characterized in that, The specific steps of the preparation method are as follows: S8-1: Add deionized water to the material tank according to the formula ratio, add panthenol at a speed of 150~250 rpm, stir for 10~20 min, add antibacterial and detoxifying adjuvant powder, homogenize for 5~10 min, and then perform ultrasonic treatment for 10~15 min with an ultrasonic power of 200~300 W. S8-2: Adjust the rotation speed to 600~700 rpm, add citrus peel extract and glycyrrhizin to the material tank in sequence, continue stirring for 10~30 min, then add water-based polyurethane emulsion dropwise, keep stirring for 10~30 min, finally add pH adjuster, stir for 10~30 min, filter through 200~300 mesh filter cloth, and then let stand and mature in the dark for 10~16 h to obtain the biocompatible antibacterial and detoxifying water-based paint.

9. The method for preparing a biocompatible antibacterial and detoxifying water-based paint according to claim 8, characterized in that, The homogenization rotation speed in S8-1 is 8000~10000 rpm.

10. The method for preparing a biocompatible antibacterial and detoxifying water-based paint according to claim 8, characterized in that, In S8-2, the pH is adjusted to 5.5~6.5 using a pH adjuster.

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