Vacuum feeding device for drug sensitivity analysis system
The automated feeding and heated tube cutting technology using a vacuum feeding device solves the problems of low efficiency and large errors in traditional drug sensitivity analysis, enabling efficient and accurate feeding and separation of antibiotic solutions and improving the stability of analytical results.
Patent Information
- Application Number
- CN202311273579.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-09-28
- Publication Date
- 2026-02-06
AI Technical Summary
Traditional drug sensitivity analysis involves manual loading, which is inefficient and prone to errors, leading to biased analytical results.
The system employs a vacuum feeding device, which utilizes automated vacuum feeding and heated tube cutting technology to achieve automated feeding and separation of antibiotic solutions, reducing manpower consumption and improving efficiency.
It reduces errors from manual operation, improves material feeding efficiency, ensures the accuracy and stability of analysis results, and prevents harmful gases from posing a threat to the environment.
Smart Images
Figure CN121472004A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of drug sensitivity analysis, and particularly relates to a vacuum feeding device for a drug sensitivity analysis system. BACKGROUND
[0002] The drug sensitivity analysis system is a system for evaluating the sensitivity of different bacteria to antibiotics, and can detect the killing effect of different types of antibiotics on bacteria and evaluate the degree of drug resistance of bacteria to antibiotics according to microbiological standard operating procedures.
[0003] The core components of the drug sensitivity analysis system generally include culture medium, drug plates, bacterial blocks, and reading instruments. Generally, these systems have specific test cards and project settings for different types of bacteria and antibiotics, and the detection process is to place bacteria on culture medium containing different concentrations of antibiotics to determine whether they can grow and whether the antibiotics have a killing effect on the bacteria. In summary, the drug sensitivity analysis system can help doctors select appropriate antibiotics to treat bacterial infections, and based on the test results, a more reasonable plan can be made for the selection of different types of antibiotics, thereby effectively resisting drug resistance.
[0004] In the traditional drug sensitivity analysis operation, the antibiotic solution with a pre-prepared concentration needs to be directly applied to the culture medium or the drug sensitivity analysis special plate by manual operation. However, manual operation not only consumes manpower and is inefficient, but also is prone to errors in manual operation, thereby easily leading to large deviations in the analysis results. SUMMARY
[0005] In order to reduce the consumption of manpower, improve the feeding efficiency, and prevent errors in manual operation to reduce the situation that the analysis results have large deviations, the present application provides a vacuum feeding device for a drug sensitivity analysis system.
[0006] The vacuum feeding device for a drug sensitivity analysis system provided by the present application adopts the following technical scheme:
[0007] The vacuum feeding device for a drug sensitivity analysis system comprises a base, a vacuum box and a first moving mechanism are arranged on the base, a movable cover is arranged on the first moving mechanism, the movable cover is used for covering the vacuum box, an inner end of the movable cover is lap-jointed with a placing seat, the placing seat comprises a first placing position and a second placing position, a microplate is placed in the first placing position, a medicine tank is placed in the second placing position, and a feeding pipe is connected between the microplate and the medicine tank; a second moving mechanism is arranged on the vacuum box, a pipe cutting assembly is arranged on the second moving mechanism, the pipe cutting assembly comprises a heating wire, and the heating wire is used for cutting the feeding pipe.
[0008] Preferably, the first moving mechanism comprises a first motor, a screw rod assembly, a first guide assembly and a first moving seat, the first guide assembly is fixedly arranged on the base, the first moving seat is movably arranged on the first guide assembly, the first motor and the screw rod assembly are fixedly arranged on the base, the first motor is connected with the screw rod assembly and the screw rod assembly is connected with the first moving seat, the movable cover is arranged on one side of the first moving seat facing the vacuum box.
[0009] Preferably, the vacuum box is provided with a mounting plate, the second moving mechanism comprises a second motor, a synchronous assembly, a second guide assembly and a second moving seat, the second guide assembly is fixedly arranged on the mounting plate, the second moving seat is movably arranged on the second guide assembly, the second motor and the synchronous assembly are fixedly arranged on the mounting plate, the second motor is connected with the second moving seat through the synchronous assembly, and the pipe cutting assembly is arranged on the second moving seat.
[0010] Preferably, the placing seat comprises a first placing position for placing the micro-hole plate and a second placing position for placing the medicine tank, the first placing position is provided with a placing groove, the second placing position is provided with a placing hole, the placing groove of the first placing position is provided with a plate outlet, one end of the placing seat provided with the plate outlet is further provided with a vacuum limiting assembly, the vacuum limiting assembly comprises a gas tank and a limiting plate, the gas tank is fixedly arranged at the end of the placing seat, the limiting plate is provided with a plurality of telescopic rods at the bottom, the limiting plate is telescopically arranged at the top of the gas tank through the plurality of telescopic rods, the gas tank is filled with gas, the pressure of the gas in the gas tank is consistent with the pressure of the atmosphere, and in the normal pressure state, the top surface of the limiting plate is located at the same height as the bottom surface of the placing groove of the first placing position.
[0011] Preferably, the second placing position is provided with a placing hole, the bottom of the placing hole of the second placing position is provided with a tank outlet, the bottom of the placing seat is provided with an inner-outer telescopic receiving plate, the receiving plate and the bottom of the placing seat are connected with a return spring, the receiving plate is compressed during the inward retraction and leaves the tank outlet, and the receiving plate is extended and moved to the tank outlet under the resetting action of the return spring; the receiving plate is connected with a control rod, the second moving seat is connected with a control plate, one side of the control plate is structured as an abutting inclined surface, the control plate is farther away from the vacuum box than the heating wire, and in the process that the heating wire cuts the pipe of the feeding pipe, the abutting inclined surface of the control plate is used to press the outer end of the control rod.
[0012] Preferably, the second moving seat is provided with an air cylinder, the two ends of the air cylinder are respectively an air inlet end and an air outlet end, a filter core is fixedly arranged in the air cylinder, and an exhaust fan is rotatably arranged in the air cylinder, a rotating shaft is rotatably arranged on the second moving seat, a bevel gear set is arranged between the rotating shaft and the exhaust fan, a gear is sleeved on the rotating shaft, and a rack is arranged on the placing seat, and during the cutting of the heating wire on the feeding pipe, the gear is engaged with the rack.
[0013] Preferably, the outer wall of the vacuum box is provided with a plurality of ribs.
[0014] Preferably, a sealing ring is arranged between the telescopic rod and the air tank, and the sealing ring between the telescopic rod and the air tank is a silica gel sealing ring.
[0015] Preferably, the bottom of the base is provided with a recycling box, and the recycling box is used for collecting the medicine tank falling down.
[0016] Preferably, a filter plate is arranged in the recycling box, and the filter plate divides the recycling box into upper and lower spaces.
[0017] The beneficial effects of the present application are:
[0018] 1. The vacuum feeding device of the drug sensitivity analysis system can reduce labor consumption, improve feeding efficiency, and prevent errors caused by manual operation, so as to reduce the deviation of the analysis result.
[0019] 2. When the vacuum limiting assembly is pushed into the vacuum box together with the placing seat and is in a negative pressure environment, the limiting plate is pushed out to rise under the pressure in the air tank, and the limiting plate after rising blocks the plate outlet of the first placing position, so that the limiting plate can limit the position of the microplate in the vacuum box, thereby improving the stability of the vacuum feeding of the microplate in the vacuum box.
[0020] 3. During the process of pulling the microplate and the medicine tank out of the vacuum box, the heating wire first cuts the feeding pipe between the microplate and the medicine tank, then the control plate abuts against the control rod, and pushes the control rod to move inward through the abutting slope, the control rod drives the receiving plate to retract inward synchronously, so that the medicine tank after cutting is automatically dropped, and in this way, the heating wire and the control plate cut the multiple feeding pipes and make the multiple medicine tanks automatically drop after cutting, so that the step of manually taking the tank is omitted, the labor consumption is further reduced, and the operation efficiency of the device is further improved.
[0021] 4. When the microporous plate and medicine container are pulled out of the vacuum chamber, the second moving seat moves the heating wire closer to the feeding pipe, thereby cutting the feeding pipe. At the same time, the second moving seat moves the gear closer to the rack, so that the gear meshes with the rack. Then, as the microporous plate and medicine container are pulled out further, the rack will drive the gear to rotate. The gear will then drive the exhaust fan in the air cylinder to rotate through the bevel gear set, so that the air cylinder can absorb the harmful gases generated by the pipe cutting. The harmful gases are then preliminarily treated by the filter element in the air cylinder, thereby preventing the harmful gases from harming the workers in the same environment. Attached Figure Description
[0022] Figure 1 This is a schematic diagram of the overall structure of the vacuum feeding device in the embodiments of this application;
[0023] Figure 2 This is a schematic diagram of the vacuum chamber structure in an embodiment of this application;
[0024] Figure 3 This is an exploded view of the structure between the overlapping plate and the placement seat in an embodiment of this application;
[0025] Figure 4 This is a partial structural schematic diagram of the vacuum feeding device in the embodiments of this application;
[0026] Figure 5 This is a schematic diagram of the structure of the placement seat having an outlet on one side in an embodiment of this application;
[0027] Figure 6 This is a schematic diagram of the bottom structure of the placement base in an embodiment of this application;
[0028] Explanation of reference numerals in the attached drawings: 1. Base; 11. Recycling bin; 2. Vacuum box; 21. Fixed cover; 22. Movable cover; 221. Overlap plate; 23. Rib; 24. First air hole; 25. Second air hole; 26. Mounting plate; 31. First motor; 32. Screw; 33. Screw block; 34. First slide rail; 35. First slide block; 36. First movable seat; 4. Placement seat; 41. First placement position; 411. Discharge port; 42. Second placement position; 421. Can outlet; 43. Rack; 51. Medicine container; 52. 53. Feeding pipe; 53. Micro-perforated plate; 531. Small air hole; 532. Cavity; 61. Heating box; 62. Heating wire; 71. Second motor; 72. Synchronous pulley; 73. Synchronous belt; 74. Second slide rail; 75. Second slide block; 76. Second moving seat; 761. Control board; 762. Abutting inclined surface; 763. Air cylinder; 764. Rotating shaft; 765. Bevel gear set; 766. Gear; 81. Air box; 82. Telescopic rod; 83. Limiting plate; 91. Receiving plate; 92. Return spring; 93. Control rod. Detailed Implementation
[0029] The application will be further described below with reference to the accompanying drawings and embodiments. Figures 1-6 The application will be further described below with reference to the accompanying drawings and embodiments.
[0030] The embodiment discloses a vacuum feeding device for a drug sensitivity analysis system.
[0031] Referring to Figure 1 and Figure 2 The vacuum feeding device for the drug sensitivity analysis system comprises a vacuum box 2, the vacuum box 2 has a cavity, and opposite sides of the vacuum box 2 in the horizontal direction are respectively provided with openings, one of the openings is fixedly connected with a fixed cover 21, and the other opening is movably connected with a movable cover 22, the movable cover 22 is movable towards or away from the opening on one side of the vacuum box 2, the movable cover 22 can close the opening on one side of the vacuum box 2 by moving towards the vacuum box 2, the movable cover 22 can open the opening on one side of the vacuum box 2 by moving away from the vacuum box 2, and the vacuum box 2 is used for vacuumizing in a closed state when the movable cover 22 and the fixed cover 21 respectively close the openings on the two sides of the vacuum box 2. The bottom of the vacuum box 2 is connected with a base 1, and the vacuum box 2 is installed on the equipment of the drug sensitivity analysis system through the base 1.
[0032] Referring to Figure 2 The outer wall of the vacuum box 2 is provided with a plurality of rib strips 23, and the plurality of rib strips 23 are used for improving the strength of the vacuum box 2. One side of the vacuum box 2 is provided with a first air hole 24 and a second air hole 25, the vacuum box 2 is connected with a vacuum pump through the first air hole 24, and the vacuum pump is used for vacuumizing the vacuum box 2, and the second air hole 25 is used for adjusting the pressure in the vacuum box 2 in cooperation with the vacuum pump. When the negative pressure in the vacuum box 2 is too large, the air inlet through the adjustment of the second air hole 25 can timely adjust the pressure and the vacuum degree in the vacuum box 2, and the safety is ensured.
[0033] Referring to Figure 1 To realize the movement of the movable cover 22 relative to the opening on one side of the vacuum box 2, a first moving mechanism is arranged outside the opening on the side of the vacuum box 2, the first moving mechanism comprises a first motor 31, a screw rod assembly, a first guide assembly and a first moving seat 36, the first guide assembly is fixedly arranged on the base 1, the first moving seat 36 is movably arranged on the first guide assembly, the first guide assembly guides the moving direction of the first moving seat 36, so that the first moving seat 36 moves towards or away from the opening on one side of the vacuum box 2, the first motor 31 and the screw rod assembly are also fixedly arranged on the base 1, the first motor 31 is connected with the screw rod assembly, and the screw rod assembly is connected with the first moving seat 36, and the first motor 31 drives the first moving seat 36 to move through the screw rod assembly. The movable cover 22 is arranged on the side of the first moving seat 36 facing the vacuum box 2, and finally, the movement of the movable cover 22 relative to the opening on one side of the vacuum box 2 is realized through the arrangement of the first moving mechanism.
[0034] With reference to Figure 1 Specifically, the first guiding assembly includes a first sliding rail 34 and a first sliding seat 35. The first sliding rail 34 is fixedly arranged on the base 1, so that the first guiding assembly is fixedly arranged on the base 1 as a whole. The first sliding seat 35 is slidingly arranged on the first sliding rail 34. The first moving seat 36 is movably arranged on the first sliding rail 34 of the first guiding assembly by being fixedly connected with the first sliding seat 35. The screw rod assembly includes a screw rod 32 and a screw block 33. The screw rod 32 is rotatably arranged on the base 1. The axis of the screw rod 32 is parallel to the length direction of the first sliding rail 34. The screw block 33 is fixedly connected with the bottom of the first moving seat 36. The screw block 33 is threadedly connected with the screw rod 32. The output shaft of the first motor 31 is coaxially and fixedly connected with one end of the screw rod 32. Therefore, the process that the first motor 31 drives the first moving seat 36 is as follows: the first motor 31 drives the screw rod 32 to rotate first. Due to the guiding effect of the first guiding assembly on the first moving seat 36, the rotation of the screw block 33 fixedly connected with the bottom of the first moving seat 36 is limited. Thus, the screw block 33 moves along the axis direction of the screw rod 32, and finally drives the first moving seat 36 to move along the guiding direction of the first guiding assembly. In addition, the first moving seat 36 is L-shaped and has a vertical connection between a horizontal plate and a vertical plate. The first moving seat 36 is fixedly connected with the first sliding seat 35 and the screw block 33 through the horizontal plate. The first moving seat 36 is fixedly connected with the movable cover 22 through the vertical plate. The horizontal plate and the vertical plate of the first moving seat 36 are connected with a connecting plate, so as to improve the connection stability between the horizontal plate and the vertical plate of the first moving seat 36.
[0035] With reference to Figure 1 and Figure 3The inner side of the movable cover 22 is fixedly provided with a horizontal lap plate 221, and the lap plate 221 is lapped with a placing seat 4, which is used for placing a microplate 53 and a medicine tank 51, so that the movable cover 22 synchronously pushes the microplate 53 and the medicine tank 51 into the vacuum box 2 during the closing process, and the movable cover 22 synchronously pulls the microplate 53 and the medicine tank 51 out of the vacuum box 2 during the opening process. The microplate 53 is a culture medium for culturing bacteria in the application, and a plurality of small air holes 531 and a cavity 532 for accommodating bacteria and antibiotics are arranged in the microplate 53. The plurality of small air holes 531 are in communication with the cavity 532, and the plurality of small air holes 531 are arranged on the top of the microplate 53. In addition, the cavity 532 of the microplate 53 is exposed to one side surface of the microplate 53. In order to prevent the bacteria and the antibiotics from leaking from the surface, the microplate 53 is provided with a transparent plate on the side surface of the microplate 53, which is used for observing the growth of the bacteria in the subsequent process. The medicine tank 51 stores the antibiotic solution, and the medicine tank 51 is connected with the microplate 53 through a feeding pipe 52. The feeding pipe 52 connects the inside of the medicine tank 51 with the cavity 532 of the microplate 53, and a one-way valve is arranged in the microplate 53, which is used for preventing the antibiotic solution in the microplate 53 from flowing back to the medicine tank 51. Therefore, the feeding process of the antibiotic solution in the application is as follows: the microplate 53 and the medicine tank 51 are placed on the extracted placing seat 4 and connected through the feeding pipe 52, then the placing seat 4 is pushed into the vacuum box 2, and the vacuum environment is sealed. During the vacuum process, the antibiotic solution in the medicine tank 51 is automatically supplemented into the cavity 532 of the microplate 53 with the formation of the negative pressure state, so as to realize the vacuum feeding. Then the microplate 53 and the medicine tank 51 are pulled out of the vacuum box 2. Since the microplate 53 has the anti-backflow effect, the antibiotic solution in the microplate 53 can be prevented from flowing back to the medicine tank 51 due to the recovery of the air pressure.
[0036] Referring to Figure 3 A plurality of placing positions are arranged on the placing seat 4, so that a plurality of microplates 53 and a plurality of medicine tanks 51 can be placed on the placing seat 4. The number of the plurality of microplates 53 is consistent with the number of the plurality of medicine tanks 51. The plurality of microplates 53 and the plurality of medicine tanks 51 are connected through a plurality of feeding pipes 52 one by one, so that the vacuum feeding device of the drug sensitivity analysis system in the application can simultaneously realize the automatic feeding of the antibiotic solution in the plurality of microplates 53.
[0037] Since the microplate 53 and the medicine tank 51 are still connected through the feeding pipe 52 after being pulled out of the vacuum box 2, and only the microplate 53 is used for culturing and observing bacteria in the subsequent process, the microplate 53 and the medicine tank 51 need to be separated. For this purpose, referring to Figure 1 and Figure 4In the present application, the vacuum feeding device of the drug sensitivity analysis system further comprises a pipe cutting assembly, the pipe cutting assembly comprises a heating wire 62, and the pipe cutting assembly is connected with a second moving mechanism. During the process of pushing the microplate 53 and the medicine tank 51 into the vacuum box 2, the second moving mechanism controls the pipe cutting assembly to move away from the placing seat 4 to avoid the pushing process. During the process of pulling the microplate 53 and the medicine tank 51 out of the vacuum box 2, the second moving mechanism controls the pipe cutting assembly to move close to the placing seat 4, so that the heating wire 62 of the pipe cutting assembly is located on the pulling path of the plurality of feeding pipes 52, thereby causing the plurality of feeding pipes 52 to be fused and cut one by one during the pulling process, so as to realize the automatic separation between the microplate 53 and the medicine tank 51. Moreover, the advantage of fusing and cutting the feeding pipe 52 by using the heating wire 62 is that the high-temperature shrinkage at the fusion and cutting section can realize automatic sealing, thereby further preventing liquid leakage. Correspondingly, the feeding pipe 52 can be made of a material that is easy to be cut by high temperature, such as a plastic pipe.
[0038] With reference to Figure 1 and Figure 4 , the vacuum box 2 is provided with a mounting plate 26 at one end close to the movable cover 22, the second moving mechanism comprises a second motor 71, a synchronous assembly, a second guide assembly and a second moving seat 76. The second guide assembly is fixedly arranged on the mounting plate 26, the second moving seat 76 is movably arranged on the second guide assembly, the second guide assembly guides the movement of the second moving seat 76 close to or away from the placing table, the second motor 71 and the synchronous assembly are also fixedly arranged on the mounting plate 26, and the second motor 71 is connected with the second moving seat 76 through the synchronous assembly, thereby controlling the movement of the second moving seat 76. The pipe cutting assembly further comprises a heating box 61, the heating box 61 is fixedly arranged on the second moving seat 76, the heating box 61 is provided with a control circuit board and a heating element, and the heating wire 62 is extended from the heating box 61, thereby realizing the movement control of the heating wire 62 by the second moving mechanism.
[0039] With reference to Figure 4Specifically, the second guide assembly includes a second slide rail 74 and a second slide block 75. The second slide rail 74 is fixedly mounted on the mounting plate 26, so that the second guide assembly is entirely fixed on the mounting plate 26. The second slide block 75 is slidably mounted on the second slide rail 74. The second movable seat 76 is fixedly connected to the second slide block 75, so that the second movable seat 76 is movably mounted on the second guide assembly. Additionally, the synchronization assembly includes a timing belt 73 and two timing pulleys 72. The two timing belts 73 are rotatably mounted on the mounting plate 26. The rotation axes 764 of the two timing pulleys 72 are parallel. The timing belt 73 is tensioned between the two timing pulleys 72, and the timing belt 73 is fixedly connected to the second movable seat 76. The output shaft of the second motor 71 is coaxially and fixedly connected to one of the synchronous pulleys 72. Therefore, the process of the second moving mechanism driving the heating wire 62 to move is as follows: the second motor 71 drives one of the synchronous pulleys 72 to rotate, the two synchronous pulleys 72 then drive the synchronous belt 73 to move, and the synchronous belt 73 then drives the second moving seat 76 to move along the guiding direction of the second guide component, so that the second moving seat 76 drives the heating wire 62 to move closer to or away from the placement seat 4, so as to cut the tube or avoid it.
[0040] In summary, the vacuum loading device of the drug sensitivity analysis system of the present invention, through automated vacuum loading and automated heating tube cutting, can reduce manpower consumption, improve loading efficiency, and prevent errors caused by manual operation during the loading process of antibiotic solutions, thereby reducing the possibility of large deviations in analysis results.
[0041] Reference Figure 5The placement seat 4 includes a first placement position 41 for placing the microporous plate 53 and a second placement position 42 for placing the medicine container 51. In this embodiment, to correspond to the shapes of the microporous plate 53 and the medicine container 51, the first placement position 41 has a placement groove, and the second placement position 42 has a placement hole. The placement groove of the first placement position 41 is open at one end away from the placement hole of the second placement position 42 to form a plate outlet 411. By opening the plate outlet 411, the microporous plate 53 can be pushed out of the placement seat 4 by the automated mechanism in the subsequent steps after vacuum feeding and hot melt tube cutting. Furthermore, a vacuum limiting component is also provided at one end of the placement seat 4 where the outlet 411 is provided. The vacuum limiting component includes an air box 81 and a limiting plate 83. The air box 81 is fixedly installed at the end of the placement seat 4. Multiple telescopic rods 82 are provided at the bottom of the limiting plate 83. The limiting plate 83 is extended and retracted vertically on the top of the air box 81 through the multiple telescopic rods 82. The length of the limiting plate 83 extends along the distribution direction of the first placement position 41. The air box 81 is filled with gas. The pressure of the gas in the air box 81 is the same as the pressure of atmospheric pressure. Under normal pressure, the top surface of the limiting plate 83 is at the same height as the bottom surface of the placement groove of the first placement position 41. When the vacuum limiting assembly is pushed into the vacuum chamber 2 along with the placement seat 4 and both are in a negative pressure environment, the limiting plate 83 is pushed outward by the greater pressure inside the gas chamber 81 to achieve upward movement. After rising, the limiting plate 83 blocks the outlet 411 of the first placement position 41, so that the limiting plate 83 can limit the position of the microporous plate 53 inside the vacuum chamber 2, thereby improving the stability of the microporous plate 53 during vacuum feeding inside the vacuum chamber 2. It should be noted that, in order to balance the sealing performance of the gas chamber 81 and the sliding performance of the telescopic rod 82, a sealing ring with a low coefficient of friction is provided between the telescopic rod 82 and the gas chamber 81. In this embodiment, the sealing ring between the telescopic rod 82 and the gas chamber 81 is a silicone sealing ring. In other embodiments, a polytetrafluoroethylene sealing ring can also be used, and a lubricant can be appropriately applied to the sealing contact surface.
[0042] After the cutting assembly cuts the feed pipe 52 between the microplate 53 and the drug container 51, if the drug container 51 still needs to be manually removed, there is a problem of inconvenience in removing the container. To solve this problem, the vacuum feeding device of the drug sensitivity analysis system of the present invention has been further improved. Specifically, refer to... Figure 6The bottoms of the placement holes in the multiple second placement positions 42 are open to form a can outlet 421. The size of the can outlet 421 must ensure that the medicine can 51 can be lowered as a whole. The bottom of the placement base 4 is provided with multiple retractable support plates 91. It should be noted that the process of the support plate 91 moving closer to the center of the bottom of the placement base 4 is the process of retracting inward, and the process of the support plate 91 moving away from the center of the bottom of the placement base 4 is the process of extending outward. The number of receiving plates 91 corresponds to the number of can outlets 421. A return spring 92 connects the receiving plate 91 to the bottom of the placement seat 4. When the receiving plate 91 retracts inward under external force, it compresses the return spring 92. After retracting inward, the receiving plate 91 can move away from the can outlet 421 of the second placement position 42. After the external force is removed, the receiving plate 91 extends outward under the return action of the return spring 92. After extending outward, the receiving plate 91 can move to the can outlet 421 of the second placement position 42, so that the receiving plate 91 can receive the bottom of the medicine can 51. Therefore, when the receiving plate 91 retracts, the medicine can 51 after the tube is cut can fall freely through the can outlet 421 to leave the second placement position 42 of the placement seat 4. When the receiving plate 91 extends, it can receive the medicine can 51 and place it in the second placement position 42 of the placement seat 4.
[0043] Furthermore, refer to Figure 1 , Figure 4 and Figure 6 Each receiving plate 91 is fixedly connected to a control rod 93. The control rod 93 moves synchronously with the receiving plate 91. When the receiving plate 91 extends outward, the outer end of the control rod 93 extends beyond the bottom of the placement seat 4. In addition, it is necessary to ensure that the control rod 93 avoids the can dropping from the can outlet 421 to prevent the control rod 93 from affecting the normal dropping of the medicine can 51. Correspondingly, the second moving seat 76, which controls the movement of the heating wire 62, is also fixedly connected to a control plate 761 downward. The control plate 761 is at the same height as the control rod 93. The side of the control plate 761 facing the control rod 93 is constructed as an abutment slope 762. The abutment slope 762 of the control plate 761 is used to press against the outer end of the control rod 93. The control plate 761 is further away from the vacuum box 2 than the heating wire 62. The purpose of setting up the control plate 761 and the control rod 93 is as follows: During the process of pulling the microporous plate 53 and the medicine canister 51 out of the vacuum chamber 2, the heating wire 62 first cuts the feeding pipe 52 between the microporous plate 53 and the medicine canister 51. Then, the control plate 761 abuts against the control rod 93 and pushes the control rod 93 inward by abutting the inclined surface 762. The control rod 93 then simultaneously drives the receiving plate 91 to retract inward, so that the medicine canister 51 automatically falls into the canister after the pipe is cut. In this way, the heating wire 62 and the control plate 761 cut multiple feeding pipes 52 in sequence and make multiple medicine canisters 51 automatically fall into the canister after the pipe is cut, eliminating the step of manually removing the canister, further reducing the consumption of manpower and further improving the operating efficiency of the device.
[0044] Reference Figure 1 and Figure 3 Both the overlapping plate 221 and the base 1 are equipped with corresponding structures to avoid the falling of the medicine canister 51, allowing it to fall smoothly under the base 1. To better collect the falling medicine canister 51, a collection box 11 is provided at the bottom of the base 1. The collection box 11 is used to collect the falling medicine canister 51 uniformly. Furthermore, a filter plate is provided inside the collection box 11, dividing it into upper and lower spaces. The filter plate intercepts the medicine canister 51, causing it to collect in the upper space of the collection box 11. When residual antibiotic solution in the medicine canister 51 leaks out due to factors such as canister breakage during falling, the antibiotic solution can drip through the filter plate into the lower space of the collection box 11, thereby separating the medicine canister 51 from the leaked antibiotic solution.
[0045] Because the heating wire 62 generates harmful gases during the high-temperature cutting of the feed pipe 52, if these harmful gases are released directly without preliminary treatment, they can easily harm workers in the same environment. Therefore, this invention further improves upon these improvements to address the aforementioned problems. Specifically, refer to... Figure 1 and Figure 4 The second movable seat 76, used to move the heating wire 62, is also equipped with an air cylinder 763. The two ends of the air cylinder 763 are an air inlet and an air outlet, respectively. In this embodiment, the end of the air cylinder 763 facing the placement seat 4 is the air inlet. A filter element is fixedly installed inside the air cylinder 763, and an exhaust fan is rotatably installed. The exhaust fan rotates to allow surrounding air to enter the air cylinder 763, be treated by the filter element, and then discharged. Furthermore, a rotating shaft 764 is rotatably installed on the second movable seat 76. A bevel gear set 765 is installed between the rotating shaft 764 and the exhaust fan. Additionally, a gear 766 is sleeved on the rotating shaft 764. A rack 43 is installed on the placement seat 4, with the length of the rack 43 parallel to the moving direction of the placement seat 4. During the process of the heating wire 62 cutting the feed tube 52, the gear 766 meshes with the rack 43. The purpose of the above structure is as follows: When the microporous plate 53 and the medicine tank 51 are pulled out of the vacuum box 2, the second moving seat 76 drives the heating wire 62 to approach the feeding pipe 52, thereby cutting the feeding pipe 52. At the same time, the second moving seat 76 drives the gear 766 to approach the rack 43, so that the gear 766 meshes with the rack 43. Then, as the microporous plate 53 and the medicine tank 51 are pulled out further, the rack 43 will drive the gear 766 to rotate. The gear 766 then drives the exhaust fan in the air cylinder 763 to rotate through the bevel gear set 765, so that the air cylinder 763 can absorb the harmful gases generated by the pipe cutting, and perform preliminary treatment of the harmful gases through the filter element in the air cylinder 763, thereby preventing the harmful gases from causing harm to the workers in the same environment.
[0046] The operation process of the vacuum loading device of the drug sensitivity analysis system of the present invention is as follows: First, multiple microplates 53 and drug containers 51 are placed on the placement seat 4, and the microplates 53 and the placement seat 4 are interconnected through the loading pipe 52; then, the microplates 53 and drug containers 51 are pushed into the vacuum chamber 2 for vacuum loading. During this process, the heating wire 62 avoids the pushing of the microplates 53 and drug containers 51; during the vacuum loading process, the vacuum limiting component on one side of the placement seat 4 limits the position of the microplates 53 to maintain the micropores. The positional stability of plate 53 during vacuum feeding; after vacuum feeding is completed, the movable cover 22 is opened slightly, and then the heating wire 62 is controlled to approach the placement seat 4 so that the heating wire 62 is located on the pull-out path of the feeding tube 52; then the microporous plate 53 and the medicine tank 51 are completely pulled out. During the pulling process, the heating wire 62 sequentially performs high-temperature tube cutting on multiple feeding tubes 52, and the receiving plate 91 retracts sequentially so that the medicine tank 51 after tube cutting automatically falls into the tank. The filter element in the air cylinder 763 performs preliminary treatment on the harmful gases generated by high-temperature tube cutting.
[0047] The above are all preferred embodiments of the present invention and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.
Claims
1. A vacuum feeding device for a drug sensitivity analysis system, characterized in that: The device includes a base (1), on which a vacuum chamber (2) and a first moving mechanism are provided. The first moving mechanism is provided with a movable cover (22), which is used to cover the vacuum chamber (2). The inner end of the movable cover (22) is connected to a placement seat (4). The placement seat (4) includes a first placement position (41) and a second placement position (42). The first placement position (41) is used to place a microporous plate (53), and the second placement position (42) is used to place a medicine container (51). A feeding tube (52) is connected between the microporous plate (53) and the medicine container (51). The vacuum chamber (2) is provided with a second moving mechanism, on which a tube cutting assembly is provided. The tube cutting assembly includes a heating wire (62), which is used to cut the feeding tube (52).
2. The vacuum feeding device for a drug sensitivity analysis system according to claim 1, characterized in that: The first moving mechanism includes a first motor (31), a lead screw assembly, a first guide assembly, and a first moving seat (36). The first guide assembly is fixedly mounted on the base (1), and the first moving seat (36) is movably mounted on the first guide assembly. The first motor (31) and the lead screw assembly are fixedly mounted on the base (1). The first motor (31) is connected to the lead screw assembly, and the lead screw assembly is connected to the first moving seat (36). The movable cover (22) is located on the side of the first moving seat (36) facing the vacuum chamber (2).
3. The vacuum feeding device for a drug sensitivity analysis system according to claim 1, characterized in that: The vacuum chamber (2) is provided with a mounting plate (26). The second moving mechanism includes a second motor (71), a synchronization component, a second guide component, and a second moving seat (76). The second guide component is fixedly mounted on the mounting plate (26), and the second moving seat (76) is movably mounted on the second guide component. The second motor (71) and the synchronization component are fixedly mounted on the mounting plate (26). The second motor (71) is connected to the second moving seat (76) through the synchronization component. The tube cutting component is mounted on the second moving seat (76).
4. The vacuum feeding device for a drug sensitivity analysis system according to claim 1, characterized in that: The first placement position (41) is provided with a placement groove, and the placement groove of the first placement position (41) is provided with an outlet (411). The placement seat (4) is provided with a vacuum limiting component at one end of the outlet (411). The vacuum limiting component includes an air box (81) and a limiting plate (83). The air box (81) is fixedly installed at the end of the placement seat (4). The bottom of the limiting plate (83) is provided with multiple telescopic rods (82). The limiting plate (83) is telescopically installed on the top of the air box (81) through the multiple telescopic rods (82). The air box (81) is filled with gas. The pressure of the gas in the air box (81) is the same as the pressure of atmospheric pressure. Under normal pressure, the top surface of the limiting plate (83) and the bottom surface of the placement groove of the first placement position (41) are at the same height.
5. A vacuum feeding device for a drug sensitivity analysis system according to claim 3, characterized in that: The second placement position (42) has a placement hole, and the bottom of the placement hole of the second placement position (42) has a can outlet (421). The bottom of the placement seat (4) is provided with an inwardly and outwardly retractable support plate (91). A return spring (92) is connected between the support plate (91) and the bottom of the placement seat (4). When the support plate (91) retracts inward, it compresses the return spring (92) and moves away from the can outlet (421). Under the return action of the return spring (92), the support plate (91) moves forward. The rod extends and moves to the outlet (421); the receiving plate (91) is connected to the control rod (93), and the second moving seat (76) is connected to the control plate (761). One side of the control plate (761) is constructed as an abutting slope (762). The control plate (761) is further away from the vacuum box (2) than the heating wire (62). During the process of the heating wire (62) cutting the feed tube (52), the abutting slope (762) of the control plate (761) is used to press against the outer end of the control rod (93).
6. A vacuum feeding device for a drug sensitivity analysis system according to claim 3, characterized in that: The second movable seat (76) is provided with an air cylinder (763), the two ends of which are the air inlet and the air outlet, respectively. A filter element is fixedly installed inside the air cylinder (763) and an exhaust fan is rotatably installed. A rotating shaft (764) is rotatably installed on the second movable seat (76). A bevel gear set (765) is provided between the rotating shaft (764) and the exhaust fan. A gear (766) is sleeved on the rotating shaft (764). A rack (43) is provided on the placement seat (4). During the process of the heating wire (62) cutting the feed tube (52), the gear (766) meshes with the rack (43).
7. A vacuum feeding device for a drug sensitivity analysis system according to claim 1, characterized in that: The outer wall of the vacuum chamber (2) is provided with multiple ribs (23).
8. A vacuum feeding device for a drug sensitivity analysis system according to claim 4, characterized in that: A sealing ring is provided between the telescopic rod (82) and the air box (81), and the sealing ring between the telescopic rod (82) and the air box (81) is a silicone sealing ring.
9. A vacuum feeding device for a drug sensitivity analysis system according to claim 5, characterized in that: A recycling bin (11) is provided at the bottom of the base (1), and the recycling bin (11) is used to collect the fallen medicine canister (51).
10. A vacuum feeding device for a drug sensitivity analysis system according to claim 9, characterized in that: The recycling bin (11) is equipped with a filter plate, which divides the recycling bin (11) into upper and lower spaces.